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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Zbtb6

Z-value: 0.98

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Transcription factors associated with Zbtb6

Gene Symbol Gene ID Gene Info
Zbtb6
ENSRNOG00000009340 zinc finger and BTB domain containing 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zbtb6rn6_v1_chr3_-_21684132_216841320.276.2e-07Click!

Activity profile of Zbtb6 motif

Sorted Z-values of Zbtb6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_105279462 53.16 ENSRNOT00000010679
Scg5
secretogranin V
chr10_-_103816287 49.02 ENSRNOT00000004477
Grin2c
glutamate ionotropic receptor NMDA type subunit 2C
chr1_-_31122093 46.33 ENSRNOT00000016712
NEWGENE_1307525
SOGA family member 3
chr10_-_90999506 45.22 ENSRNOT00000034401
Gfap
glial fibrillary acidic protein
chr17_+_88215834 42.96 ENSRNOT00000034098
Gpr158
G protein-coupled receptor 158
chr10_-_27366665 42.37 ENSRNOT00000004725
Gabra1
gamma-aminobutyric acid type A receptor alpha1 subunit
chr2_+_174013288 29.51 ENSRNOT00000013904
Serpini1
serpin family I member 1
chr12_-_23925741 28.85 ENSRNOT00000001957
Srrm3
serine/arginine repetitive matrix 3
chr16_-_18937562 27.22 ENSRNOT00000080387
Nwd1
NACHT and WD repeat domain containing 1
chr7_+_78092037 26.93 ENSRNOT00000050753
Rims2
regulating synaptic membrane exocytosis 2
chr7_+_145117951 25.24 ENSRNOT00000055272
Pde1b
phosphodiesterase 1B
chr8_+_48382121 24.34 ENSRNOT00000008685
Thy1
Thy-1 cell surface antigen
chrX_+_114929029 24.08 ENSRNOT00000006459
Pak3
p21 (RAC1) activated kinase 3
chr10_-_51669297 23.78 ENSRNOT00000071595
Arhgap44
Rho GTPase activating protein 44
chr14_+_25589762 22.56 ENSRNOT00000043938
ENSRNOT00000067439
ENSRNOT00000002793
Epha5
EPH receptor A5
chr1_+_214927172 22.41 ENSRNOT00000027134
Brsk2
BR serine/threonine kinase 2
chr8_-_98738446 22.24 ENSRNOT00000019860
Zic1
Zic family member 1
chr18_+_30435119 21.80 ENSRNOT00000027190
Pcdhb8
protocadherin beta 8
chr10_-_89958805 21.38 ENSRNOT00000084266
Mpp3
membrane palmitoylated protein 3
chr3_-_94182714 21.17 ENSRNOT00000015073
LOC100362814
hypothetical protein LOC100362814
chrX_-_115764217 20.16 ENSRNOT00000009400
Trpc5
transient receptor potential cation channel, subfamily C, member 5
chr3_+_172374957 17.38 ENSRNOT00000035916
Gnas
GNAS complex locus
chr3_-_15278645 16.95 ENSRNOT00000032204
Ttll11
tubulin tyrosine ligase like11
chr13_+_51022681 16.94 ENSRNOT00000078599
Chi3l1
chitinase 3 like 1
chr20_-_53777159 16.65 ENSRNOT00000073994
AABR07045621.1

chr10_+_103308392 16.59 ENSRNOT00000004141
Kif19
kinesin family member 19
chr5_-_62621737 16.46 ENSRNOT00000011573
Gabbr2
gamma-aminobutyric acid type B receptor subunit 2
chr2_+_3400977 16.27 ENSRNOT00000093593
Mctp1
multiple C2 and transmembrane domain containing 1
chr11_+_87366621 15.93 ENSRNOT00000040978
Aifm3
apoptosis inducing factor, mitochondria associated 3
chr15_-_33576331 15.68 ENSRNOT00000021851
Slc22a17
solute carrier family 22, member 17
chr18_-_56331991 15.04 ENSRNOT00000085841
ENSRNOT00000091220
Slc6a7
solute carrier family 6 member 7
chr7_+_23403891 15.02 ENSRNOT00000037918
Syn3
synapsin III
chr13_+_71086745 14.80 ENSRNOT00000083366
Rgs8
regulator of G-protein signaling 8
chr14_-_114484127 14.79 ENSRNOT00000056706
Eml6
echinoderm microtubule associated protein like 6
chr17_-_48562838 14.27 ENSRNOT00000017102
ENSRNOT00000084702
Amph
amphiphysin
chrX_+_2435305 13.95 ENSRNOT00000005623
Slc9a7
solute carrier family 9 member A7
chr18_+_52917124 13.64 ENSRNOT00000021921
Slc12a2
solute carrier family 12 member 2
chr1_+_172752416 13.51 ENSRNOT00000087448
Olr268
olfactory receptor 268
chr1_+_221801524 13.37 ENSRNOT00000031227
Nrxn2
neurexin 2
chr1_-_220136470 12.29 ENSRNOT00000026812
Actn3
actinin alpha 3
chrX_-_22440187 12.25 ENSRNOT00000090731
Gpr173

chr3_-_175479395 12.16 ENSRNOT00000077308
Hrh3
histamine receptor H3
chr8_+_24369916 12.11 ENSRNOT00000033460
Bmper
BMP-binding endothelial regulator
chr19_-_58735173 11.98 ENSRNOT00000030077
Pcnx2
pecanex homolog 2 (Drosophila)
chr1_+_221792221 11.68 ENSRNOT00000054828
Nrxn2
neurexin 2
chr2_+_41911131 11.16 ENSRNOT00000016768
Plk2
polo-like kinase 2
chr3_+_92403582 11.08 ENSRNOT00000064282
Pamr1
peptidase domain containing associated with muscle regeneration 1
chr8_+_122003916 10.77 ENSRNOT00000091980
Clasp2
cytoplasmic linker associated protein 2
chr7_-_70480724 10.40 ENSRNOT00000090057
Dtx3
deltex E3 ubiquitin ligase 3
chr5_+_123905166 10.37 ENSRNOT00000082021
Dab1
DAB1, reelin adaptor protein
chr8_+_117620317 10.34 ENSRNOT00000084220
Celsr3
cadherin, EGF LAG seven-pass G-type receptor 3
chr7_-_134722215 10.26 ENSRNOT00000036750
Prickle1
prickle planar cell polarity protein 1
chr14_-_83741969 10.22 ENSRNOT00000026293
Inpp5j
inositol polyphosphate-5-phosphatase J
chr11_+_45888221 10.13 ENSRNOT00000071932
ENSRNOT00000066008
ENSRNOT00000060802
Lnp1
leukemia NUP98 fusion partner 1
chr2_+_187740531 10.11 ENSRNOT00000092653
Paqr6
progestin and adipoQ receptor family member 6
chr4_+_13405136 9.97 ENSRNOT00000091004
Gnai1
G protein subunit alpha i1
chr19_+_24329544 9.94 ENSRNOT00000080934
Tbc1d9
TBC1 domain family member 9
chr8_+_63379087 9.61 ENSRNOT00000012091
ENSRNOT00000012295
Nptn
neuroplastin
chr5_-_150949931 9.16 ENSRNOT00000067905
Smpdl3b
sphingomyelin phosphodiesterase, acid-like 3B
chr16_-_19308842 9.11 ENSRNOT00000019556
Fam32a
family with sequence similarity 32, member A
chr17_-_45154355 8.91 ENSRNOT00000084976
Zkscan4
zinc finger with KRAB and SCAN domains 4
chr15_-_28733513 8.80 ENSRNOT00000078180
Sall2
spalt-like transcription factor 2
chr8_+_116096458 8.20 ENSRNOT00000021188
RGD1307461
similar to RIKEN cDNA 6430571L13 gene; similar to g20 protein
chr1_+_162320730 8.12 ENSRNOT00000035743
Kctd21
potassium channel tetramerization domain containing 21
chr10_-_102576878 8.02 ENSRNOT00000091129
Sdk2
sidekick cell adhesion molecule 2
chr17_-_90218013 7.68 ENSRNOT00000072803
Impad1
inositol monophosphatase domain containing 1
chr5_+_156615886 7.51 ENSRNOT00000076439
Sh2d5
SH2 domain containing 5
chrX_-_70428364 7.41 ENSRNOT00000045907
P2ry4
pyrimidinergic receptor P2Y4
chr2_-_139528162 7.36 ENSRNOT00000014317
Slc7a11
solute carrier family 7 member 11
chr11_+_82194657 7.33 ENSRNOT00000002445
Etv5
ets variant 5
chr20_+_9791171 7.26 ENSRNOT00000078031
Abcg1
ATP binding cassette subfamily G member 1
chrX_-_71313513 7.09 ENSRNOT00000004972
ENSRNOT00000076008
ENSRNOT00000076042
Zmym3
zinc finger MYM-type containing 3
chr1_+_215609036 6.79 ENSRNOT00000076187
Tnni2
troponin I2, fast skeletal type
chr3_-_29996865 6.76 ENSRNOT00000080382
Zeb2
zinc finger E-box binding homeobox 2
chr11_+_86903122 6.59 ENSRNOT00000048063
Zdhhc8
zinc finger, DHHC-type containing 8
chr1_-_198233215 6.54 ENSRNOT00000087928
Aldoa
aldolase, fructose-bisphosphate A
chrX_+_40258493 6.46 ENSRNOT00000033010
Mbtps2
membrane-bound transcription factor peptidase, site 2
chr8_+_48472824 6.39 ENSRNOT00000010463
ENSRNOT00000090780
Mcam
melanoma cell adhesion molecule
chr3_-_125213607 6.03 ENSRNOT00000078070
Gpcpd1
glycerophosphocholine phosphodiesterase 1
chr9_-_81868086 5.74 ENSRNOT00000067080
Zfp142
zinc finger protein 142
chrX_-_152932953 5.72 ENSRNOT00000078929
Cetn2
centrin 2
chr18_+_17403407 5.72 ENSRNOT00000045150
RGD1562608
similar to KIAA1328 protein
chr20_+_4530342 5.60 ENSRNOT00000076352
ENSRNOT00000000478
ENSRNOT00000075925
Nelfe
negative elongation factor complex member E
chr10_-_70646495 5.38 ENSRNOT00000071218
Gas2l2
growth arrest-specific 2 like 2
chr11_+_83048636 5.36 ENSRNOT00000002408
RGD1562339
RGD1562339
chr7_+_2605719 5.32 ENSRNOT00000018737
Gls2
glutaminase 2
chr2_+_208749996 4.92 ENSRNOT00000086321
Chia
chitinase, acidic
chr17_-_90217786 4.86 ENSRNOT00000073534
Impad1
inositol monophosphatase domain containing 1
chr2_+_208750356 4.74 ENSRNOT00000041562
Chia
chitinase, acidic
chr14_+_78973364 4.67 ENSRNOT00000089759
Mrfap1
Morf4 family associated protein 1
chr4_+_145580799 4.60 ENSRNOT00000013727
Vhl
von Hippel-Lindau tumor suppressor
chr4_+_157511642 4.57 ENSRNOT00000065846
Pianp
PILR alpha associated neural protein
chr11_+_60613882 4.54 ENSRNOT00000002853
Slc35a5
solute carrier family 35, member A5
chr5_-_17663500 4.26 ENSRNOT00000033151
ENSRNOT00000034495
Impad1
inositol monophosphatase domain containing 1
chr7_-_116284587 4.23 ENSRNOT00000073179
LOC100910656
ly-6/neurotoxin-like protein 1-like
chrX_+_22313028 4.21 ENSRNOT00000082725
Kdm5c
lysine demethylase 5C
chr1_-_172943853 4.15 ENSRNOT00000047040
Olr278
olfactory receptor 278
chr6_-_33738825 4.11 ENSRNOT00000039492
Slc7a15
solute carrier family 7 (cationic amino acid transporter, y+ system), member 15
chr16_-_71319449 4.09 ENSRNOT00000029284
Fgfr1
Fibroblast growth factor receptor 1
chr2_+_189714754 4.05 ENSRNOT00000086285
Gatad2b
GATA zinc finger domain containing 2B
chr3_+_152402520 4.00 ENSRNOT00000027086
Cnbd2
cyclic nucleotide binding domain containing 2
chr9_-_37231291 3.96 ENSRNOT00000016237
Ptp4a1
protein tyrosine phosphatase type IVA, member 1
chr12_-_16126953 3.95 ENSRNOT00000001682
Lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr17_+_45078556 3.83 ENSRNOT00000088280
Zfp192
zinc finger protein 192
chr7_+_116980076 3.68 ENSRNOT00000012321
Zfp623
zinc finger protein 623
chr1_+_220137257 3.56 ENSRNOT00000026832
Zdhhc24
zinc finger, DHHC-type containing 24
chr4_+_170347410 3.48 ENSRNOT00000040508
LOC500350
LRRGT00139
chr4_+_123801174 3.43 ENSRNOT00000029055
RGD1560289
similar to chromosome 3 open reading frame 20
chr10_-_63491713 3.41 ENSRNOT00000063941
Tusc5
tumor suppressor candidate 5
chr1_-_163129641 3.32 ENSRNOT00000083055
Capn5
calpain 5
chr7_+_143882000 3.32 ENSRNOT00000017110
ENSRNOT00000091053
Mfsd5
major facilitator superfamily domain containing 5
chr7_-_12762341 3.29 ENSRNOT00000064886
Abca7
ATP binding cassette subfamily A member 7
chr1_+_255479261 3.20 ENSRNOT00000079808
Tnks2
tankyrase 2
chr10_+_78168715 3.18 ENSRNOT00000072294
Cox11
COX11 cytochrome c oxidase copper chaperone
chr1_-_169721758 3.09 ENSRNOT00000023213
LOC100910107
ubiquitin carboxyl-terminal hydrolase DUB-1-like
chr1_-_103380338 3.09 ENSRNOT00000019061
Mrgprx4
MAS related GPR family member X4
chr11_+_64761146 3.07 ENSRNOT00000051428
Poglut1
protein O-glucosyltransferase 1
chr1_-_241046249 3.02 ENSRNOT00000067796
ENSRNOT00000081866
Smc5
structural maintenance of chromosomes 5
chr7_-_140172448 2.96 ENSRNOT00000077672
LOC103692976
cyclin-T1-like
chr5_-_6186329 2.94 ENSRNOT00000012610
Sulf1
sulfatase 1
chr8_+_5522739 2.94 ENSRNOT00000011507
Mmp13
matrix metallopeptidase 13
chr16_-_71319052 2.87 ENSRNOT00000050980
Fgfr1
Fibroblast growth factor receptor 1
chr2_+_211078334 2.86 ENSRNOT00000049127
Sort1
sortilin 1
chr3_-_175479034 2.75 ENSRNOT00000086761
Hrh3
histamine receptor H3
chr2_+_202200797 2.68 ENSRNOT00000042263
ENSRNOT00000071938
Spag17
sperm associated antigen 17
chr6_-_144123596 2.64 ENSRNOT00000006144
ENSRNOT00000087845
Wdr60
WD repeat domain 60
chr15_-_82482009 2.62 ENSRNOT00000011926
Dach1
dachshund family transcription factor 1
chr3_-_67668772 2.53 ENSRNOT00000010247
Frzb
frizzled-related protein
chr1_+_170242846 2.47 ENSRNOT00000023751
Cnga4
cyclic nucleotide gated channel alpha 4
chr7_-_134602239 2.46 ENSRNOT00000006780
Zcrb1
zinc finger CCHC-type and RNA binding motif containing 1
chr1_+_257517242 2.45 ENSRNOT00000073502
ENSRNOT00000018668
ENSRNOT00000078738
ENSRNOT00000091663
ENSRNOT00000072002
LOC685933
hypothetical protein LOC685933
chr14_-_93042182 2.43 ENSRNOT00000005432
LOC100361025
protein arginine methyltransferase 1-like
chr8_+_70447040 2.43 ENSRNOT00000016798
Ints14
integrator complex subunit 14
chr3_-_164366684 2.41 ENSRNOT00000035048
LOC679539
similar to ubiquitin-conjugating enzyme E2 variant 1
chr10_+_17542374 2.33 ENSRNOT00000064079
Fbxw11
F-box and WD repeat domain containing 11
chr10_-_49196177 2.27 ENSRNOT00000084418
Zfp286a
zinc finger protein 286A
chr10_+_34185898 2.24 ENSRNOT00000003339
Trim7
tripartite motif-containing 7
chr1_+_172283255 2.24 ENSRNOT00000049260
Olr247
olfactory receptor 247
chr3_-_119075606 2.20 ENSRNOT00000041569
ENSRNOT00000086724
Hdc
histidine decarboxylase
chr3_+_147894558 2.10 ENSRNOT00000055415
LOC502684
hypothetical protein LOC502684
chr9_+_81868265 2.09 ENSRNOT00000022632
Bcs1l
BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone
chr10_+_47785033 1.90 ENSRNOT00000075073
ENSRNOT00000084944
B9d1
B9 domain containing 1
chr5_-_151029233 1.88 ENSRNOT00000089155
Ppp1r8
protein phosphatase 1, regulatory subunit 8
chr1_-_82088275 1.75 ENSRNOT00000072616
Dedd2
death effector domain containing 2
chr1_+_266451021 1.70 ENSRNOT00000027196
Borcs7
BLOC-1 related complex subunit 7
chr13_+_26172243 1.69 ENSRNOT00000003840
Phlpp1
PH domain and leucine rich repeat protein phosphatase 1
chr10_-_84847857 1.63 ENSRNOT00000071495
LOC102552549
migration and invasion enhancer 1-like
chr8_-_94368834 1.58 ENSRNOT00000078977
Me1
malic enzyme 1
chr1_-_219412816 1.56 ENSRNOT00000083204
ENSRNOT00000029580
Rps6kb2
ribosomal protein S6 kinase B2
chr1_+_172892134 1.47 ENSRNOT00000087918
Olr276
olfactory receptor 276
chr1_-_172395872 1.38 ENSRNOT00000055174
Olr252
olfactory receptor 252
chr1_-_90151405 1.38 ENSRNOT00000028688
RGD1308428
similar to RIKEN cDNA 4931406P16
chr4_+_87827582 1.35 ENSRNOT00000077211
LOC108348088
putative vomeronasal receptor-like protein 4
chr20_+_3823042 1.25 ENSRNOT00000041613
Rxrb
retinoid X receptor beta
chr1_+_172807389 1.22 ENSRNOT00000088537
Olr271
olfactory receptor 271
chr20_-_3822754 1.22 ENSRNOT00000000541
ENSRNOT00000077357
Slc39a7
solute carrier family 39 member 7
chr8_+_114916122 1.21 ENSRNOT00000074194
Tlr9
toll-like receptor 9
chr8_-_63350269 1.16 ENSRNOT00000042681
Cd276
Cd276 molecule
chr1_-_44474674 1.10 ENSRNOT00000078768
Tfb1m
transcription factor B1, mitochondrial
chr10_+_94988362 1.04 ENSRNOT00000066525
Cep95
centrosomal protein 95
chr1_+_213194827 1.01 ENSRNOT00000044878
Olr306
olfactory receptor 306
chr13_+_37400476 0.94 ENSRNOT00000003435
Ccdc93
coiled-coil domain containing 93
chr14_+_85142279 0.93 ENSRNOT00000011281
Thoc5
THO complex 5
chr19_+_53629779 0.89 ENSRNOT00000051352
Map1lc3b
microtubule-associated protein 1 light chain 3 beta
chr10_+_14689094 0.89 ENSRNOT00000036630
RGD1559662
similar to implantation serine proteinase 2
chr1_+_172792874 0.79 ENSRNOT00000077837
Olr270
olfactory receptor 270
chr10_-_86554478 0.79 ENSRNOT00000049621
Ormdl3
ORMDL sphingolipid biosynthesis regulator 3
chr10_-_82197520 0.78 ENSRNOT00000092024
Cacna1g
calcium voltage-gated channel subunit alpha1 G
chr16_+_7435634 0.75 ENSRNOT00000026323
Capn7
calpain 7
chr6_+_93740586 0.65 ENSRNOT00000011466
Dact1
dishevelled-binding antagonist of beta-catenin 1
chr1_-_172369515 0.63 ENSRNOT00000040363
Olr251
olfactory receptor 251
chr2_-_177924970 0.58 ENSRNOT00000029340
Rapgef2
Rap guanine nucleotide exchange factor 2
chr7_-_120919261 0.57 ENSRNOT00000019612
Josd1
Josephin domain containing 1
chr15_+_33555640 0.52 ENSRNOT00000021096
Pabpn1
poly(A) binding protein, nuclear 1
chr18_-_48720472 0.50 ENSRNOT00000023236
Cep120
centrosomal protein 120
chr12_-_11783232 0.44 ENSRNOT00000075888
Zfp498
zinc finger protein 498
chr19_+_37668693 0.42 ENSRNOT00000084970
Pard6a
par-6 family cell polarity regulator alpha
chr10_+_61071278 0.39 ENSRNOT00000073002
Olr1516
olfactory receptor 1516
chr1_-_172932507 0.34 ENSRNOT00000048478
RGD1564933
similar to olfactory receptor Olr271
chr9_-_99680979 0.33 ENSRNOT00000049347
Olr1345
olfactory receptor 1345
chr10_+_14722756 0.31 ENSRNOT00000025220
Tpsb2
tryptase beta 2
chr5_-_135994848 0.31 ENSRNOT00000067675
Btbd19
BTB domain containing 19
chr10_+_63677396 0.28 ENSRNOT00000005100
Slc43a2
solute carrier family 43 member 2
chr12_+_11433813 0.22 ENSRNOT00000031901
ENSRNOT00000084577
Smurf1
SMAD specific E3 ubiquitin protein ligase 1
chr16_+_80826681 0.21 ENSRNOT00000000123
Coprs
coordinator of PRMT5 and differentiation stimulator
chr10_-_50574539 0.19 ENSRNOT00000034261
Cox10
COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
chr3_-_73636542 0.15 ENSRNOT00000074870
LOC100909831
olfactory receptor 8K3-like
chr1_-_216274930 0.07 ENSRNOT00000040850
Trpm5
transient receptor potential cation channel, subfamily M, member 5
chr1_+_64480929 0.04 ENSRNOT00000087016
Olr1l
olfactory receptor 1-like
chr9_+_100885051 0.04 ENSRNOT00000082987
AC109427.1

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
16.3 49.0 GO:0033058 directional locomotion(GO:0033058)
8.1 24.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
7.5 45.2 GO:0010625 positive regulation of Schwann cell proliferation(GO:0010625) regulation of chaperone-mediated autophagy(GO:1904714)
5.9 23.8 GO:0098886 modification of dendritic spine(GO:0098886)
5.8 17.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
5.2 15.7 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
5.0 20.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
4.5 13.6 GO:0070634 transepithelial ammonium transport(GO:0070634)
4.2 25.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
4.1 12.3 GO:0033123 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) positive regulation of purine nucleotide catabolic process(GO:0033123)
3.5 10.4 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
3.1 43.2 GO:0071420 cellular response to histamine(GO:0071420)
2.7 53.2 GO:0016486 peptide hormone processing(GO:0016486)
2.5 14.9 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
2.4 9.6 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
2.3 32.5 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
2.3 6.8 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
2.2 6.5 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
2.1 25.2 GO:0036005 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
2.1 16.8 GO:0006021 inositol biosynthetic process(GO:0006021)
2.1 26.9 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
2.1 10.3 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
1.9 9.7 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
1.8 7.3 GO:0034436 glycoprotein transport(GO:0034436)
1.8 5.3 GO:0006543 glutamine catabolic process(GO:0006543)
1.7 12.2 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
1.7 17.0 GO:0018095 protein polyglutamylation(GO:0018095)
1.5 4.6 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
1.5 15.0 GO:0035524 proline transmembrane transport(GO:0035524)
1.5 7.3 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
1.3 9.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
1.2 7.4 GO:0030321 transepithelial chloride transport(GO:0030321)
1.1 10.3 GO:0051890 regulation of cardioblast differentiation(GO:0051890)
1.1 14.8 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
1.1 10.8 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.1 14.0 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
1.0 3.1 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
1.0 12.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
1.0 16.9 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
1.0 3.9 GO:0007386 compartment pattern specification(GO:0007386)
1.0 2.9 GO:0060686 esophagus smooth muscle contraction(GO:0014846) negative regulation of prostatic bud formation(GO:0060686)
0.8 2.5 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.8 11.7 GO:0032486 Rap protein signal transduction(GO:0032486)
0.8 3.3 GO:1902995 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.8 24.1 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.7 2.7 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.7 3.3 GO:0060014 granulosa cell differentiation(GO:0060014)
0.6 3.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.6 5.6 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.6 3.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.6 10.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.6 2.9 GO:0048227 plasma membrane to endosome transport(GO:0048227) negative regulation of lipoprotein lipase activity(GO:0051005)
0.6 1.7 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.6 2.2 GO:0001692 histamine metabolic process(GO:0001692)
0.5 6.0 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.5 16.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.5 3.0 GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.5 6.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.5 22.2 GO:0007628 adult walking behavior(GO:0007628)
0.4 2.6 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.4 7.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.4 4.7 GO:0006013 mannose metabolic process(GO:0006013)
0.4 22.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.4 2.4 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.4 1.2 GO:0032741 positive regulation of interleukin-18 production(GO:0032741)
0.4 1.2 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.3 22.4 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.3 8.0 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.3 14.3 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.3 0.8 GO:1900060 negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060)
0.3 1.5 GO:0099638 endosome to plasma membrane protein transport(GO:0099638)
0.2 2.9 GO:0001554 luteolysis(GO:0001554)
0.2 14.9 GO:0097194 execution phase of apoptosis(GO:0097194)
0.2 6.6 GO:0018345 protein palmitoylation(GO:0018345)
0.2 6.4 GO:0003094 glomerular filtration(GO:0003094)
0.2 12.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.2 0.8 GO:0010045 response to nickel cation(GO:0010045)
0.2 4.4 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.2 0.9 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.2 1.4 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.2 3.1 GO:0007635 chemosensory behavior(GO:0007635)
0.2 21.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 1.6 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.2 43.0 GO:0072659 protein localization to plasma membrane(GO:0072659)
0.1 6.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.8 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.7 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.1 15.0 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.1 27.6 GO:0010976 positive regulation of neuron projection development(GO:0010976)
0.1 0.9 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.4 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.1 2.3 GO:0042753 negative regulation of NF-kappaB import into nucleus(GO:0042347) positive regulation of circadian rhythm(GO:0042753)
0.1 2.4 GO:0006301 postreplication repair(GO:0006301)
0.1 0.5 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.1 5.7 GO:0006289 nucleotide-excision repair(GO:0006289)
0.1 0.8 GO:0097264 self proteolysis(GO:0097264)
0.1 1.1 GO:0031167 rRNA methylation(GO:0031167)
0.1 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.9 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.1 8.6 GO:0021915 neural tube development(GO:0021915)
0.1 1.3 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.0 0.8 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 1.9 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 1.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 6.1 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 2.6 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.5 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 1.9 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.2 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 2.5 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
11.3 45.2 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
5.5 16.5 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
2.9 49.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
1.9 5.7 GO:0071942 XPC complex(GO:0071942)
1.8 42.4 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
1.5 10.8 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
1.4 5.6 GO:0032021 NELF complex(GO:0032021)
1.4 24.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
1.1 36.5 GO:0060077 inhibitory synapse(GO:0060077)
0.7 27.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.7 2.6 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.6 3.0 GO:0035061 interchromatin granule(GO:0035061)
0.6 6.8 GO:0005861 troponin complex(GO:0005861)
0.5 2.7 GO:1990716 axonemal central apparatus(GO:1990716)
0.5 23.8 GO:0048786 presynaptic active zone(GO:0048786)
0.5 4.6 GO:0030891 VCB complex(GO:0030891)
0.4 14.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.3 29.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.3 20.9 GO:0034704 calcium channel complex(GO:0034704)
0.3 14.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.3 3.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 16.6 GO:0005871 kinesin complex(GO:0005871)
0.2 1.2 GO:0032009 early phagosome(GO:0032009)
0.2 2.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 6.5 GO:0031430 M band(GO:0031430)
0.2 0.8 GO:0035339 SPOTS complex(GO:0035339)
0.2 18.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 10.2 GO:0043198 dendritic shaft(GO:0043198)
0.1 3.3 GO:0001891 phagocytic cup(GO:0001891)
0.1 9.7 GO:0055037 recycling endosome(GO:0055037)
0.1 25.1 GO:0098793 presynapse(GO:0098793)
0.1 2.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 25.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 38.2 GO:0030141 secretory granule(GO:0030141)
0.1 16.5 GO:0005903 brush border(GO:0005903)
0.1 1.8 GO:0036038 MKS complex(GO:0036038)
0.1 0.9 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.9 GO:0044754 autolysosome(GO:0044754)
0.1 2.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 5.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 50.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 3.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 7.7 GO:0005814 centriole(GO:0005814)
0.1 7.5 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 9.0 GO:0043209 myelin sheath(GO:0043209)
0.1 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 27.7 GO:0043025 neuronal cell body(GO:0043025)
0.1 11.9 GO:0031965 nuclear membrane(GO:0031965)
0.0 8.1 GO:0031301 integral component of organelle membrane(GO:0031301)
0.0 16.7 GO:0005768 endosome(GO:0005768)
0.0 2.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.9 GO:0005795 Golgi stack(GO:0005795)
0.0 1.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.5 GO:0030659 cytoplasmic vesicle membrane(GO:0030659) cytoplasmic vesicle part(GO:0044433)
0.0 1.0 GO:0000922 spindle pole(GO:0000922)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.5 42.4 GO:0008503 benzodiazepine receptor activity(GO:0008503) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
6.3 25.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
6.1 49.0 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
5.6 16.8 GO:0008254 3'-nucleotidase activity(GO:0008254)
4.5 13.6 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
4.4 26.6 GO:0004568 chitinase activity(GO:0004568)
4.1 16.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
4.1 24.3 GO:0034235 GPI anchor binding(GO:0034235)
3.6 25.1 GO:0097109 neuroligin family protein binding(GO:0097109)
3.4 10.2 GO:0052743 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) inositol tetrakisphosphate phosphatase activity(GO:0052743)
3.0 14.9 GO:0004969 histamine receptor activity(GO:0004969)
2.9 17.4 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
2.9 2.9 GO:0010465 nerve growth factor receptor activity(GO:0010465)
2.5 7.4 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
2.5 7.4 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
2.4 7.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041) glycoprotein transporter activity(GO:0034437)
2.3 22.6 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
2.0 6.0 GO:2001070 starch binding(GO:2001070)
2.0 24.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
1.9 9.6 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
1.8 5.3 GO:0004359 glutaminase activity(GO:0004359)
1.7 22.4 GO:0050321 tau-protein kinase activity(GO:0050321)
1.7 10.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
1.5 15.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
1.4 20.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
1.4 14.0 GO:0015386 potassium:proton antiporter activity(GO:0015386)
1.3 9.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
1.1 5.7 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
1.1 5.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.0 16.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
1.0 3.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
1.0 6.8 GO:0031014 troponin T binding(GO:0031014)
0.9 6.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.9 12.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.9 7.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.7 2.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.6 11.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.5 3.3 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.5 10.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.5 1.6 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948)
0.5 50.1 GO:0051082 unfolded protein binding(GO:0051082)
0.5 23.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.5 1.8 GO:0008158 hedgehog receptor activity(GO:0008158)
0.4 10.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.4 2.4 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.4 14.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.4 1.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.4 2.6 GO:0045503 dynein light chain binding(GO:0045503)
0.4 40.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.4 1.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.3 2.6 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 10.2 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.3 29.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 16.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 1.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.2 1.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 4.7 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.2 1.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.2 33.0 GO:0044325 ion channel binding(GO:0044325)
0.2 0.8 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.2 3.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 2.9 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.2 4.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 6.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 21.9 GO:0030165 PDZ domain binding(GO:0030165)
0.1 3.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.8 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 6.0 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 4.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 3.3 GO:0030552 cAMP binding(GO:0030552)
0.1 2.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 9.3 GO:0005496 steroid binding(GO:0005496)
0.1 17.4 GO:0008514 organic anion transmembrane transporter activity(GO:0008514)
0.1 48.3 GO:0005509 calcium ion binding(GO:0005509)
0.1 0.7 GO:0070097 delta-catenin binding(GO:0070097)
0.1 14.8 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 3.2 GO:0005507 copper ion binding(GO:0005507)
0.1 2.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.8 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 4.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.1 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 15.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 4.5 GO:0008017 microtubule binding(GO:0008017)
0.0 3.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 24.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.7 10.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.4 24.1 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.4 15.0 PID EPHA FWDPATHWAY EPHA forward signaling
0.3 14.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.3 10.4 PID REELIN PATHWAY Reelin signaling pathway
0.3 29.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.3 4.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 7.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 7.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.2 12.9 PID LKB1 PATHWAY LKB1 signaling events
0.2 4.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 6.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 14.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.3 PID ATR PATHWAY ATR signaling pathway
0.0 1.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.8 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 2.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 2.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 49.0 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
2.5 10.0 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
2.5 42.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
1.6 20.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
1.0 25.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
1.0 15.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.8 45.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.7 16.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.7 17.4 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.7 15.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.7 7.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.6 10.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.5 7.0 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.4 5.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.4 6.5 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.4 14.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.3 32.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.3 10.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 4.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 1.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 3.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 5.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 19.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 3.1 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.1 1.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.6 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.1 6.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 2.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 2.3 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 5.0 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions