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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Zbtb3

Z-value: 1.07

Motif logo

Transcription factors associated with Zbtb3

Gene Symbol Gene ID Gene Info
ENSRNOG00000019461 zinc finger and BTB domain containing 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zbtb3rn6_v1_chr1_+_224998172_2249981720.255.9e-06Click!

Activity profile of Zbtb3 motif

Sorted Z-values of Zbtb3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_84939323 107.43 ENSRNOT00000022742
myosin XVI
chr7_-_113937941 59.93 ENSRNOT00000012408
potassium two pore domain channel subfamily K member 9
chrX_+_65040934 48.69 ENSRNOT00000044006
zinc finger CCCH-type containing 12B
chr1_-_188713270 48.52 ENSRNOT00000082192
ENSRNOT00000065892
G protein-coupled receptor, class C, group 5, member B
chr3_-_176666282 48.28 ENSRNOT00000016947
eukaryotic translation elongation factor 1 alpha 2
chr16_+_26906716 47.42 ENSRNOT00000064297
carboxypeptidase E
chrX_+_65040775 45.61 ENSRNOT00000081354
zinc finger CCCH-type containing 12B
chr2_+_18392142 44.82 ENSRNOT00000043196
hyaluronan and proteoglycan link protein 1
chr20_-_13142856 41.91 ENSRNOT00000001743
S100 calcium binding protein B
chr2_-_26699333 41.39 ENSRNOT00000024459
synaptic vesicle glycoprotein 2c
chr2_-_147959567 39.04 ENSRNOT00000063986
profilin-2-like
chr3_+_71210301 38.00 ENSRNOT00000006504
family with sequence similarity 171, member B
chr1_+_80195532 37.21 ENSRNOT00000022528
reticulon 2
chr18_+_30435119 34.47 ENSRNOT00000027190
protocadherin beta 8
chr18_-_37096132 32.77 ENSRNOT00000041188
protein phosphatase 2, regulatory subunit B, beta
chr2_+_220298245 32.55 ENSRNOT00000022625
phospholipid phosphatase related 4
chr8_-_73194837 31.30 ENSRNOT00000024885
ENSRNOT00000081450
ENSRNOT00000064613
talin 2
chr6_+_29977797 31.18 ENSRNOT00000071784
FK506 binding protein 1B
chr1_-_89560719 29.46 ENSRNOT00000028653
sodium voltage-gated channel beta subunit 1
chr2_-_148050423 27.99 ENSRNOT00000064506
ENSRNOT00000023469
profilin-2-like
chr2_-_210943620 27.63 ENSRNOT00000026750
G protein-coupled receptor 61
chr1_+_226435979 27.53 ENSRNOT00000048704
ENSRNOT00000036232
ENSRNOT00000035576
ENSRNOT00000036180
ENSRNOT00000036168
ENSRNOT00000047964
ENSRNOT00000036283
ENSRNOT00000007429
synaptotagmin 7
chr15_+_5306459 27.15 ENSRNOT00000092079
CD99 antigen-like protein 2
chr11_+_69739384 24.98 ENSRNOT00000016340
kalirin, RhoGEF kinase
chr4_+_157726941 24.39 ENSRNOT00000025081
vesicle-associated membrane protein 1
chr12_-_5682608 24.26 ENSRNOT00000076483
FRY microtubule binding protein
chr3_+_48082935 23.28 ENSRNOT00000087711
ENSRNOT00000067545
solute carrier family 4 member 10
chr7_-_25743537 22.57 ENSRNOT00000083450
uncharacterized LOC100910996
chr2_+_218951451 21.10 ENSRNOT00000019190
exostosin-like glycosyltransferase 2
chr6_+_119519714 20.60 ENSRNOT00000004955
fibronectin leucine rich transmembrane protein 2
chr17_+_15966234 19.83 ENSRNOT00000084304
WNK lysine deficient protein kinase 2
chr5_+_139963002 18.09 ENSRNOT00000048506
collagen type IX alpha 2 chain
chr12_-_6740714 18.04 ENSRNOT00000001205
mesenteric estrogen-dependent adipogenesis
chr1_+_101427195 17.87 ENSRNOT00000028271
glycogen synthase 1
chr1_+_48077033 17.77 ENSRNOT00000020100
MAS1 proto-oncogene, G protein-coupled receptor
chr3_+_142739781 17.77 ENSRNOT00000006181
somatostatin receptor 4
chr7_+_139762614 17.54 ENSRNOT00000031157
coiled-coil domain containing 184
chrX_+_75792931 17.25 ENSRNOT00000037575
MAGE family member E2
chr20_+_28572242 16.99 ENSRNOT00000072485
SH3 domain containing ring finger 3
chr15_-_60752106 16.96 ENSRNOT00000058148
A-kinase anchoring protein 11
chr3_+_172692452 16.31 ENSRNOT00000077193
zinc finger protein 831
chr13_-_90641772 15.68 ENSRNOT00000064601
ATPase Na+/K+ transporting subunit alpha 4
chr3_+_161433410 15.60 ENSRNOT00000024657
solute carrier family 12 member 5
chr1_+_16478127 15.23 ENSRNOT00000019076
Abelson helper integration site 1
chr15_+_41448064 15.11 ENSRNOT00000019551
sacsin molecular chaperone
chr1_-_261333383 15.05 ENSRNOT00000037490
MORN repeat containing 4
chr14_+_79540235 14.31 ENSRNOT00000089334
sortilin-related VPS10 domain containing receptor 2
chr2_+_218951141 14.14 ENSRNOT00000091001
exostosin-like glycosyltransferase 2
chrX_+_92131209 14.09 ENSRNOT00000004462
poly A binding protein, cytoplasmic 5
chr1_+_67340809 13.11 ENSRNOT00000045266
mCG114696-like
chr7_+_143749221 12.29 ENSRNOT00000014807
insulin-like growth factor binding protein 6
chr2_+_44096061 11.54 ENSRNOT00000018438
ankyrin repeat domain 55
chr12_-_15996958 10.87 ENSRNOT00000039726
archaelysin family metallopeptidase 1
chr20_+_13067242 10.75 ENSRNOT00000083878
disco-interacting protein 2 homolog A
chr3_+_149802621 10.53 ENSRNOT00000071772
similar to Vomeromodulin
chr15_+_43582020 10.40 ENSRNOT00000013001
paraneoplastic Ma antigen 2
chr1_-_124039196 10.32 ENSRNOT00000051883
cholinergic receptor nicotinic alpha 7 subunit
chr4_+_70903253 10.21 ENSRNOT00000019720
Eph receptor B6
chr7_+_122979021 10.16 ENSRNOT00000085707
zinc finger CCCH-type containing 7B
chr1_+_273854248 9.44 ENSRNOT00000044827
ENSRNOT00000017600
ENSRNOT00000086496
adducin 3
chr17_-_88037034 9.39 ENSRNOT00000080193
ENSRNOT00000034907
phosphoribosyl transferase domain containing 1
chr18_-_29340403 8.93 ENSRNOT00000025157
heparin-binding EGF-like growth factor
chr2_+_180012414 8.76 ENSRNOT00000082273
platelet derived growth factor C
chr7_+_18510354 8.66 ENSRNOT00000060002
PML-RARA regulated adaptor molecule 1
chr12_-_47919400 8.54 ENSRNOT00000073774
mevalonate kinase
chr4_-_77706994 8.39 ENSRNOT00000038517
zinc finger protein 777
chr6_+_137967401 8.34 ENSRNOT00000029223
hypothetical protein LOC690422
chr4_-_98141482 8.27 ENSRNOT00000009883
interleukin 12 receptor subunit beta 2
chr1_+_80982358 8.21 ENSRNOT00000078462

chr15_+_39945095 7.92 ENSRNOT00000016826
shisa family member 2
chr3_-_76496283 7.74 ENSRNOT00000044305
olfactory receptor 611
chrX_-_17252877 7.49 ENSRNOT00000060213
retinitis pigmentosa 1-like 1 protein-like
chr2_+_72006099 7.44 ENSRNOT00000034044
cadherin 12
chr17_-_34945317 7.20 ENSRNOT00000090457
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr1_+_201256910 7.19 ENSRNOT00000090143
transforming, acidic coiled-coil containing protein 2
chr1_-_60088406 6.87 ENSRNOT00000091192
vomeronasal 1 receptor 7
chr3_-_44522930 6.85 ENSRNOT00000006963
activin A receptor type 1
chr3_+_67849966 6.82 ENSRNOT00000057826
dual specificity phosphatase 19
chr10_+_103934797 6.82 ENSRNOT00000035865
cerebellar degeneration-related protein 2-like
chr5_-_150723321 6.39 ENSRNOT00000018038
ATPase inhibitory factor 1
chr18_+_87580424 6.25 ENSRNOT00000070984
thioredoxin-related transmembrane protein 3
chr1_-_172322795 6.23 ENSRNOT00000075318
similar to olfactory receptor MOR204-14
chr5_+_128450680 6.14 ENSRNOT00000010700
thioredoxin domain containing 12
chr2_-_28799266 5.55 ENSRNOT00000089293
transmembrane protein 171
chr1_+_201055644 5.45 ENSRNOT00000054937
ENSRNOT00000047161
transforming, acidic coiled-coil containing protein 2
chr4_+_2711385 5.21 ENSRNOT00000035996
DnaJ heat shock protein family (Hsp40) member B6
chr9_+_16702460 5.14 ENSRNOT00000061432
protein tyrosine kinase 7
chr19_-_10358695 4.98 ENSRNOT00000019770
katanin regulatory subunit B1
chr11_-_71128299 4.76 ENSRNOT00000080568
forty-two-three domain containing 1
chr1_-_261446570 4.75 ENSRNOT00000020182
secreted frizzled-related protein 5
chr11_-_67702955 4.49 ENSRNOT00000084540
ENSRNOT00000078285
karyopherin subunit alpha 1
chr18_-_56870801 4.47 ENSRNOT00000087188
ENSRNOT00000032189
Rho guanine nucleotide exchange factor 37
chr8_+_44990014 4.25 ENSRNOT00000044608
heat shock protein family A (Hsp70) member 8
chr19_+_561727 4.13 ENSRNOT00000016259
ENSRNOT00000081547
RRAD, Ras related glycolysis inhibitor and calcium channel regulator
chr3_-_29996865 4.04 ENSRNOT00000080382
zinc finger E-box binding homeobox 2
chr6_-_1410339 4.00 ENSRNOT00000035905
HEAT repeat containing 5B
chr1_+_172807389 3.92 ENSRNOT00000088537
olfactory receptor 271
chr7_-_120636563 3.80 ENSRNOT00000091317
ENSRNOT00000031117
transmembrane protein 184B
chr8_-_128622314 3.79 ENSRNOT00000084950
ENSRNOT00000024408
golgi reassembly stacking protein 1
chr5_+_173340060 3.77 ENSRNOT00000067841
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr1_+_35067490 3.75 ENSRNOT00000022790
ADAM metallopeptidase with thrombospondin type 1 motif, 16
chr3_-_120373500 3.74 ENSRNOT00000067727
nephrocystin 1
chr14_+_86652365 3.60 ENSRNOT00000077428
zinc finger, MIZ-type containing 2
chr15_-_3773340 3.54 ENSRNOT00000063831
zinc finger SWIM domain-containing protein 8-like
chr2_-_86475096 3.39 ENSRNOT00000075247
ENSRNOT00000075062
zinc finger protein 43-like
chr18_+_60639860 3.24 ENSRNOT00000083363
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr10_+_45966926 3.23 ENSRNOT00000067584
olfactory receptor 225
chr19_+_9587653 3.22 ENSRNOT00000015956
glutamic-oxaloacetic transaminase 2
chr4_-_176026133 3.20 ENSRNOT00000043374
ENSRNOT00000046598
solute carrier organic anion transporter family, member 1a4
chr4_+_113247795 3.16 ENSRNOT00000007984
tachykinin receptor 1
chrX_-_124576133 3.14 ENSRNOT00000041904
reproductive homeobox on X chromosome 3
chr1_-_168082740 3.13 ENSRNOT00000070789
similar to olfactory receptor 555
chr4_-_146954159 3.05 ENSRNOT00000010397
TAM41 mitochondrial translocator assembly and maintenance homolog
chr8_+_31497639 2.87 ENSRNOT00000020041
sorting nexin 19
chr2_-_211235440 2.85 ENSRNOT00000033015
ENSRNOT00000091896
seryl-tRNA synthetase
chr1_+_266451021 2.67 ENSRNOT00000027196
BLOC-1 related complex subunit 7
chr18_-_16543992 2.66 ENSRNOT00000036306
solute carrier family 39 member 6
chr2_+_186980793 2.53 ENSRNOT00000091336
Rho guanine nucleotide exchange factor 11
chr2_-_144217600 2.51 ENSRNOT00000000101
regulatory factor X-associated protein-like 1
chr10_+_35343189 2.43 ENSRNOT00000083688
mitogen-activated protein kinase 9
chr7_-_18180705 2.42 ENSRNOT00000065954
zinc finger protein 494
chr5_+_173340487 2.36 ENSRNOT00000078306
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr5_-_62683964 2.35 ENSRNOT00000060005
ankyrin repeat and sterile alpha motif domain containing 6
chr4_-_100303047 2.34 ENSRNOT00000018170
ENSRNOT00000084782
methionine adenosyltransferase 2A
chr2_-_144007636 2.24 ENSRNOT00000092028
regulatory factor X-associated protein
chr5_+_69214948 2.14 ENSRNOT00000074807
olfactory receptor 844
chr6_+_1410507 2.11 ENSRNOT00000034919
G patch domain containing 11
chr8_-_22929294 1.97 ENSRNOT00000015609
RAB3D, member RAS oncogene family
chr6_+_64252020 1.95 ENSRNOT00000047296
ENSRNOT00000082105
patatin-like phospholipase domain containing 8
chr3_+_150188455 1.91 ENSRNOT00000072917

chr14_-_81426496 1.80 ENSRNOT00000018073
adducin 1
chr10_-_12818137 1.77 ENSRNOT00000060972
olfactory receptor 1382
chr2_-_210991509 1.72 ENSRNOT00000087329
cytochrome b561 family, member D1
chr1_+_265883355 1.31 ENSRNOT00000025938
ELOVL fatty acid elongase 3
chr5_-_131860637 1.25 ENSRNOT00000064569
ENSRNOT00000080242
solute carrier family 5 member 9
chr1_-_101426852 1.18 ENSRNOT00000028217
RuvB-like AAA ATPase 2
chr1_+_172792874 1.17 ENSRNOT00000077837
olfactory receptor 270
chr16_+_3817402 1.16 ENSRNOT00000015011
transmembrane protein 254
chr15_+_36565495 1.07 ENSRNOT00000028093
ATPase H+/K+ transporting non-gastric alpha2 subunit
chr9_+_93799278 1.01 ENSRNOT00000084590
DIS3-like 3'-5' exoribonuclease 2
chr7_-_122963299 1.00 ENSRNOT00000090208
RAN GTPase activating protein 1
chr15_+_31533675 0.99 ENSRNOT00000084141

chr9_+_100885051 0.95 ENSRNOT00000082987

chr5_-_166430254 0.79 ENSRNOT00000048914
nicotinamide nucleotide adenylyltransferase 1
chr5_+_166430400 0.70 ENSRNOT00000021822
leucine zipper and CTNNBIP1 domain containing
chr10_+_13915214 0.69 ENSRNOT00000015092
polycystin 1, transient receptor potential channel interacting
chr16_+_82184387 0.62 ENSRNOT00000089329
ENSRNOT00000068416
tubulin, gamma complex associated protein 3
chrX_-_75566481 0.59 ENSRNOT00000003714
zinc finger, DHHC-type containing 15
chr7_-_11783849 0.51 ENSRNOT00000026202
splicing factor 3a, subunit 2
chr1_-_204817080 0.51 ENSRNOT00000077956
family with sequence similarity 53, member B
chr4_-_51003117 0.36 ENSRNOT00000034936
taste receptor, type 2, member 118
chr13_+_49850189 0.25 ENSRNOT00000042125
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr3_+_73366155 0.04 ENSRNOT00000044979
olfactory receptor 473

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
11.7 35.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
9.5 47.4 GO:2000173 insulin processing(GO:0030070) negative regulation of branching morphogenesis of a nerve(GO:2000173)
9.2 27.5 GO:1990926 short-term synaptic potentiation(GO:1990926)
6.1 24.3 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
6.0 41.9 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
5.9 29.5 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
5.6 67.0 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
5.0 25.0 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
4.6 27.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
4.5 31.2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
3.8 15.2 GO:0039020 pronephric nephron tubule development(GO:0039020)
3.7 48.5 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
3.7 7.4 GO:0050893 sensory processing(GO:0050893)
3.1 9.4 GO:0006178 guanine salvage(GO:0006178) GMP catabolic process(GO:0046038) guanine biosynthetic process(GO:0046099)
3.0 17.8 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
2.8 8.5 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
2.8 31.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
2.6 10.2 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
2.4 4.7 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
2.2 8.9 GO:0051542 elastin biosynthetic process(GO:0051542)
2.2 32.8 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
1.8 20.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
1.7 15.6 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
1.7 5.0 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
1.6 6.4 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
1.5 107.4 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
1.5 23.3 GO:0021860 pyramidal neuron development(GO:0021860)
1.4 8.7 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
1.4 4.3 GO:0061740 protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740) regulation of lysosomal membrane permeability(GO:0097213) positive regulation of lysosomal membrane permeability(GO:0097214)
1.4 17.8 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
1.3 4.0 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
1.2 6.2 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
1.2 3.7 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
1.1 23.8 GO:0035493 SNARE complex assembly(GO:0035493)
1.1 3.2 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
1.1 3.2 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
1.0 16.7 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.9 19.8 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.9 12.6 GO:0030953 astral microtubule organization(GO:0030953)
0.8 32.6 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.8 3.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.7 48.3 GO:0006414 translational elongation(GO:0006414)
0.6 37.2 GO:0065002 intracellular protein transmembrane transport(GO:0065002)
0.6 1.2 GO:0071899 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.6 7.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.5 17.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.5 7.9 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.5 2.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.5 12.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.5 1.9 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.5 2.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.5 5.1 GO:0060484 establishment of epithelial cell apical/basal polarity(GO:0045198) lung-associated mesenchyme development(GO:0060484)
0.4 3.0 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.4 4.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.4 6.1 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.4 8.8 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.3 2.4 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.3 1.8 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.3 18.0 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.3 8.3 GO:0045622 regulation of T-helper cell differentiation(GO:0045622)
0.3 41.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3 0.8 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.3 1.3 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 4.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 2.7 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.2 0.7 GO:0072021 ascending thin limb development(GO:0072021) distal tubule morphogenesis(GO:0072156) metanephric ascending thin limb development(GO:0072218) metanephric proximal tubule development(GO:0072237)
0.2 3.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.2 3.8 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.2 41.4 GO:0006836 neurotransmitter transport(GO:0006836)
0.2 1.0 GO:0010587 miRNA catabolic process(GO:0010587)
0.2 7.9 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 1.0 GO:1904117 cellular response to vasopressin(GO:1904117)
0.1 27.3 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 0.6 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 3.7 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.1 42.4 GO:0001501 skeletal system development(GO:0001501)
0.1 0.6 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.1 2.8 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 2.5 GO:0001505 regulation of neurotransmitter levels(GO:0001505)
0.0 1.3 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 4.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 4.1 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 2.4 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 2.1 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 13.7 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.5 GO:0000245 spliceosomal complex assembly(GO:0000245)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
16.1 48.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
8.1 24.4 GO:0035577 azurophil granule membrane(GO:0035577) tertiary granule membrane(GO:0070821)
6.0 18.1 GO:0005594 collagen type IX trimer(GO:0005594)
4.7 75.0 GO:0031045 dense core granule(GO:0031045)
3.9 23.3 GO:0097441 basilar dendrite(GO:0097441)
1.8 12.3 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
1.6 31.3 GO:0005916 fascia adherens(GO:0005916)
1.6 107.4 GO:0016459 myosin complex(GO:0016459)
1.5 29.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
1.4 4.3 GO:1990836 lysosomal matrix(GO:1990836)
1.4 6.8 GO:0048179 activin receptor complex(GO:0048179)
1.3 15.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.2 37.2 GO:0098827 endoplasmic reticulum subcompartment(GO:0098827)
1.2 32.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
1.0 31.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.9 15.2 GO:0036038 MKS complex(GO:0036038)
0.8 2.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.6 7.4 GO:0032279 asymmetric synapse(GO:0032279)
0.5 59.9 GO:0008021 synaptic vesicle(GO:0008021)
0.5 67.0 GO:0043195 terminal bouton(GO:0043195)
0.5 41.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.4 15.6 GO:0032590 dendrite membrane(GO:0032590)
0.3 1.0 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.3 7.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.2 6.4 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.2 41.9 GO:0001726 ruffle(GO:0001726)
0.2 0.6 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.2 2.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 1.8 GO:0008290 F-actin capping protein complex(GO:0008290)
0.2 15.5 GO:0016234 inclusion body(GO:0016234)
0.2 1.2 GO:0097255 R2TP complex(GO:0097255)
0.2 29.2 GO:0030427 site of polarized growth(GO:0030427)
0.2 3.7 GO:0035869 ciliary transition zone(GO:0035869)
0.2 34.4 GO:0014069 postsynaptic density(GO:0014069)
0.1 20.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 2.0 GO:0042588 zymogen granule(GO:0042588)
0.1 6.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 15.7 GO:0043235 receptor complex(GO:0043235)
0.1 54.9 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 4.5 GO:0005643 nuclear pore(GO:0005643)
0.1 3.6 GO:0043596 nuclear replication fork(GO:0043596)
0.1 5.2 GO:0030018 Z disc(GO:0030018)
0.1 52.3 GO:0009986 cell surface(GO:0009986)
0.0 2.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.0 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 1.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 8.7 GO:0030054 cell junction(GO:0030054)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
11.7 35.2 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
6.7 67.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
5.9 29.5 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
4.7 41.9 GO:0050786 RAGE receptor binding(GO:0050786)
4.0 47.4 GO:0050897 cobalt ion binding(GO:0050897)
3.0 17.8 GO:0004994 somatostatin receptor activity(GO:0004994)
3.0 32.6 GO:0042577 lipid phosphatase activity(GO:0042577)
2.8 31.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
2.6 17.9 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
2.5 17.8 GO:0001595 angiotensin receptor activity(GO:0001595)
2.3 6.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
2.2 48.3 GO:0003746 translation elongation factor activity(GO:0003746)
2.1 6.4 GO:0016882 cyclo-ligase activity(GO:0016882)
1.6 44.8 GO:0005540 hyaluronic acid binding(GO:0005540)
1.6 6.2 GO:0016972 thiol oxidase activity(GO:0016972)
1.5 20.6 GO:0045499 chemorepellent activity(GO:0045499)
1.4 12.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
1.3 15.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
1.3 5.1 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
1.2 16.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
1.2 16.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
1.1 6.8 GO:0016361 activin receptor activity, type I(GO:0016361)
1.1 25.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
1.1 3.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
1.1 4.3 GO:0031686 A1 adenosine receptor binding(GO:0031686)
1.1 3.2 GO:0004995 tachykinin receptor activity(GO:0004995)
1.0 3.0 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.9 8.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.8 23.3 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.8 15.1 GO:0070628 proteasome binding(GO:0070628)
0.8 2.3 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.8 107.4 GO:0003774 motor activity(GO:0003774)
0.7 17.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.6 7.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.6 43.9 GO:0030295 protein kinase activator activity(GO:0030295)
0.6 24.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.6 59.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.5 3.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.5 10.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.5 32.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.4 6.1 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.4 27.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.4 8.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.3 5.0 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.3 31.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.3 5.2 GO:0001671 ATPase activator activity(GO:0001671)
0.3 0.8 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.2 1.9 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.2 2.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 1.8 GO:0042608 T cell receptor binding(GO:0042608)
0.2 8.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 3.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 1.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2 9.4 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.1 4.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 4.0 GO:0070412 R-SMAD binding(GO:0070412)
0.1 3.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 1.3 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 2.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 7.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 2.0 GO:0031489 myosin V binding(GO:0031489)
0.1 13.6 GO:0005516 calmodulin binding(GO:0005516)
0.1 12.6 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.1 6.9 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 2.8 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 1.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 1.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 12.0 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 4.8 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 37.7 GO:0046872 metal ion binding(GO:0046872)
0.0 4.3 GO:0005549 odorant binding(GO:0005549)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 25.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.9 47.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.8 34.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.7 32.8 PID ATR PATHWAY ATR signaling pathway
0.7 17.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.5 6.8 PID ALK2 PATHWAY ALK2 signaling events
0.5 8.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.4 18.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.3 33.7 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.2 4.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 2.5 ST GA13 PATHWAY G alpha 13 Pathway
0.1 3.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 8.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 35.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 1.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 4.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 6.6 PID CMYB PATHWAY C-MYB transcription factor network
0.1 3.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.2 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 59.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
3.0 41.9 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
1.6 24.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
1.4 35.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.8 29.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.7 8.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.6 7.4 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.4 4.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.4 27.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.4 18.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.4 8.9 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.4 8.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.3 16.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.3 7.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 21.1 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.2 2.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 4.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 2.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 15.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.9 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 1.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.6 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.2 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors