Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Zbtb12

Z-value: 0.67

Motif logo

logo of

Transcription factors associated with Zbtb12

Gene Symbol Gene ID Gene Info
Zbtb12
ENSRNOG00000000418 zinc finger and BTB domain containing 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zbtb12rn6_v1_chr20_+_4572100_4572100-0.234.9e-05Click!

Activity profile of Zbtb12 motif

Sorted Z-values of Zbtb12 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_39164916 31.74 ENSRNOT00000011309
Acrv1
acrosomal vesicle protein 1
chr20_+_19325121 29.20 ENSRNOT00000058151
Phyhipl
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr1_+_213597478 28.94 ENSRNOT00000017562
Odf3
outer dense fiber of sperm tails 3
chr5_-_17399801 24.96 ENSRNOT00000011900
RGD1563405
similar to protein tyrosine phosphatase 4a2
chr20_+_5619012 23.36 ENSRNOT00000000577
Ggnbp1
gametogenetin binding protein 1
chr18_+_68983545 23.23 ENSRNOT00000085317
Stard6
StAR-related lipid transfer domain containing 6
chr10_+_88356615 21.95 ENSRNOT00000022687
Klhl10
kelch-like family member 10
chr16_-_7007051 19.25 ENSRNOT00000023984
Itih3
inter-alpha trypsin inhibitor, heavy chain 3
chr5_-_59165160 18.69 ENSRNOT00000029035
Fam221b
family with sequence similarity 221, member B
chr12_+_17614632 18.57 ENSRNOT00000031896
Prkar1b
protein kinase cAMP-dependent type 1 regulatory subunit beta
chr1_-_227486976 18.09 ENSRNOT00000035812
Ms4a14
membrane spanning 4-domains A14
chr8_+_119121669 17.27 ENSRNOT00000028479
Prss46
protease, serine, 46
chr15_-_37409668 17.20 ENSRNOT00000011742
Gjb6
gap junction protein, beta 6
chr17_-_56269242 17.00 ENSRNOT00000021901
Lyzl1
lysozyme-like 1
chr1_+_221443896 16.73 ENSRNOT00000073942
Tmem262
transmembrane protein 262
chr2_-_265300868 15.84 ENSRNOT00000066024
ENSRNOT00000016073
ENSRNOT00000033502
Lrrc7
leucine rich repeat containing 7
chr16_+_9907598 15.82 ENSRNOT00000027352
Ptpn20
protein tyrosine phosphatase, non-receptor type 20
chr19_+_26416818 15.38 ENSRNOT00000040473
AABR07043200.1

chr7_+_129595192 15.37 ENSRNOT00000071151
Zdhhc25
zinc finger, DHHC-type containing 25
chr1_-_225035687 15.26 ENSRNOT00000026539
Gng3
G protein subunit gamma 3
chr19_-_26946044 13.56 ENSRNOT00000090756
AABR07043271.1

chr1_-_266333105 12.60 ENSRNOT00000027093
Arl3
ADP ribosylation factor like GTPase 3
chr7_+_123482255 12.46 ENSRNOT00000064487
LOC688613
hypothetical protein LOC688613
chr13_-_79899479 12.40 ENSRNOT00000035815
RGD1309106
similar to hypothetical protein
chr10_+_90988732 11.86 ENSRNOT00000003892
FAM187A
family with sequence similarity 187, member A
chr13_+_100214353 11.79 ENSRNOT00000073693
LOC686031
hypothetical protein LOC686031
chr20_-_12820466 11.16 ENSRNOT00000001699
Ftcd
formimidoyltransferase cyclodeaminase
chr3_+_47677720 10.53 ENSRNOT00000065340
Tbr1
T-box, brain, 1
chr3_+_101899068 10.44 ENSRNOT00000079600
ENSRNOT00000006256
Muc15
mucin 15, cell surface associated
chr18_-_36513317 10.10 ENSRNOT00000025453
Plac8l1
PLAC8-like 1
chr15_-_33775109 9.72 ENSRNOT00000033722
Jph4
junctophilin 4
chr2_+_187977008 9.63 ENSRNOT00000081531
ENSRNOT00000092951
Arhgef2
Rho/Rac guanine nucleotide exchange factor 2
chr16_+_51748970 9.51 ENSRNOT00000059182
Adam26a
a disintegrin and metallopeptidase domain 26A
chr1_+_99762253 9.42 ENSRNOT00000065876
Klk6
kallikrein related-peptidase 6
chr1_-_141349881 9.26 ENSRNOT00000021109
Rhcg
Rh family, C glycoprotein
chr7_-_117440342 9.13 ENSRNOT00000018528
Tssk5
testis-specific serine kinase 5
chr2_-_236480502 9.06 ENSRNOT00000015020
Sgms2
sphingomyelin synthase 2
chr10_-_29026002 8.77 ENSRNOT00000005070
Pttg1
pituitary tumor-transforming 1
chr9_-_81565416 8.48 ENSRNOT00000083582
Aamp
angio-associated, migratory cell protein
chrX_-_156540733 8.33 ENSRNOT00000091029
LOC108348261
transketolase-like protein 1
chr1_+_166428761 7.97 ENSRNOT00000085555
Stard10
StAR-related lipid transfer domain containing 10
chr8_-_96985558 7.94 ENSRNOT00000018553
LOC501033
similar to UPF0258 protein KIAA1024
chr18_-_68983619 7.67 ENSRNOT00000014670
LOC361346
similar to chromosome 18 open reading frame 54
chr2_+_206314213 7.61 ENSRNOT00000056068
Bcl2l15
BCL2-like 15
chr10_-_88357025 7.49 ENSRNOT00000080006
Nt5c3b
5'-nucleotidase, cytosolic IIIB
chr15_-_39705208 7.49 ENSRNOT00000015412
Phf11
PHD finger protein 11
chr10_+_89459650 7.13 ENSRNOT00000028149
ENSRNOT00000077942
Nbr1
NBR1, autophagy cargo receptor
chr7_-_92996025 6.66 ENSRNOT00000076327
Samd12
sterile alpha motif domain containing 12
chr12_+_37829579 6.58 ENSRNOT00000084587
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr10_-_88356538 5.96 ENSRNOT00000022430
Nt5c3b
5'-nucleotidase, cytosolic IIIB
chr3_+_55886695 5.72 ENSRNOT00000009396
Bbs5
Bardet-Biedl syndrome 5
chr3_+_143109316 5.59 ENSRNOT00000006555
LOC257643
cystatin SC
chr1_-_146968689 5.51 ENSRNOT00000023181
LOC690082
similar to melanoma ubiquitous mutated protein
chrX_+_6430594 5.50 ENSRNOT00000044009
Maob
monoamine oxidase B
chr9_-_14550625 5.26 ENSRNOT00000078227
Oard1
O-acyl-ADP-ribose deacylase 1
chr2_+_113984824 5.21 ENSRNOT00000086399
Tnik
TRAF2 and NCK interacting kinase
chr1_-_216971183 5.21 ENSRNOT00000077911
Mrgpre
MAS related GPR family member E
chrX_+_152196129 4.57 ENSRNOT00000087679
Magea4
melanoma antigen, family A, 4
chr11_+_88699222 4.46 ENSRNOT00000084177
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr6_-_91518996 4.38 ENSRNOT00000005835
Pole2
DNA polymerase epsilon 2, accessory subunit
chr2_-_250862419 4.30 ENSRNOT00000017943
Clca4
chloride channel accessory 4
chr10_-_45579029 4.28 ENSRNOT00000080028
Arf1
ADP-ribosylation factor 1
chr13_+_90692666 4.23 ENSRNOT00000010028
Igsf8
immunoglobulin superfamily, member 8
chr6_-_125853461 4.12 ENSRNOT00000007505
Atxn3
ataxin 3
chr19_-_37819789 3.71 ENSRNOT00000036702
Cenpt
centromere protein T
chrX_-_112328642 3.52 ENSRNOT00000083150
Psmd10
proteasome 26S subunit, non-ATPase 10
chr14_+_32257805 3.40 ENSRNOT00000039626
AABR07014804.1

chrX_+_156909913 3.31 ENSRNOT00000084390
L1cam
L1 cell adhesion molecule
chr2_-_23909016 3.18 ENSRNOT00000084044
Scamp1
secretory carrier membrane protein 1
chr10_-_49009156 2.98 ENSRNOT00000072970
Mapk7
mitogen-activated protein kinase 7
chr15_-_28935269 2.96 ENSRNOT00000060427
Olr1645
olfactory receptor 1645
chr13_+_71656651 2.79 ENSRNOT00000050365
Zfp648
zinc finger protein 648
chr7_+_101069104 2.77 ENSRNOT00000056894
AABR07058124.2

chr1_-_226292480 2.54 ENSRNOT00000039133
Myrf
myelin regulatory factor
chr1_+_198409360 2.53 ENSRNOT00000013691
ENSRNOT00000091295
Cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr5_-_166926636 2.24 ENSRNOT00000023287
Spsb1
splA/ryanodine receptor domain and SOCS box containing 1
chr15_-_61772516 2.21 ENSRNOT00000015605
ENSRNOT00000093399
Wbp4
WW domain binding protein 4
chr6_+_22296128 2.12 ENSRNOT00000087805
Dpy30
dpy-30 histone methyltransferase complex regulatory subunit
chr1_+_59765835 2.02 ENSRNOT00000014842
Fpr1
formyl peptide receptor 1
chr8_-_73122740 1.93 ENSRNOT00000012026
Tln2
talin 2
chr12_-_24365324 1.90 ENSRNOT00000032250
Trim50
tripartite motif-containing 50
chr3_+_100787449 1.82 ENSRNOT00000078543
Bdnf
brain-derived neurotrophic factor
chr12_+_47074200 1.82 ENSRNOT00000014910
Dynll1
dynein light chain LC8-type 1
chr1_-_144601327 1.80 ENSRNOT00000029244
ENSRNOT00000078144
Saxo2
stabilizer of axonemal microtubules 2
chr6_+_9790422 1.77 ENSRNOT00000020959
Prkce
protein kinase C, epsilon
chr14_-_108412823 1.74 ENSRNOT00000081405
Pex13
peroxisomal biogenesis factor 13
chr6_+_129609074 1.72 ENSRNOT00000064957
Papola
poly (A) polymerase alpha
chr1_+_59704998 1.60 ENSRNOT00000014598
LOC688452
hypothetical protein LOC688452
chr3_-_23353425 1.49 ENSRNOT00000019703
Golga1
golgin A1
chr1_-_199320727 1.47 ENSRNOT00000022452
Zfp668
zinc finger protein 668
chr2_+_123734199 1.40 ENSRNOT00000038729
RGD1307100
similar to RIKEN cDNA D630029K19
chr7_-_12598370 1.40 ENSRNOT00000026708
Arid3a
AT-rich interaction domain 3A
chr6_+_145740035 1.39 ENSRNOT00000064868
Cdca7l
cell division cycle associated 7 like
chr1_+_85143789 1.39 ENSRNOT00000071691
Acp7
acid phosphatase 7, tartrate resistant
chr6_-_36940868 1.36 ENSRNOT00000006470
Gen1
GEN1 Holliday junction 5' flap endonuclease
chr3_+_100786862 1.30 ENSRNOT00000080190
Bdnf
brain-derived neurotrophic factor
chr10_-_55589978 0.87 ENSRNOT00000007087
LOC100912917
phosphoribosylformylglycinamidine synthase-like
chr12_-_19254527 0.87 ENSRNOT00000089349
AABR07035541.3

chr6_+_24377327 0.71 ENSRNOT00000043641
Lclat1
lysocardiolipin acyltransferase 1
chr7_-_120780641 0.69 ENSRNOT00000076164
Ddx17
DEAD-box helicase 17
chr7_-_140580783 0.54 ENSRNOT00000087327
Dhh
desert hedgehog
chr5_+_139385429 0.53 ENSRNOT00000078622
Scmh1
sex comb on midleg homolog 1 (Drosophila)
chr1_-_78626284 0.45 ENSRNOT00000052299
LOC108349752
carcinoembryonic antigen-related cell adhesion molecule 3-like
chr11_-_29710849 0.41 ENSRNOT00000029345
Krtap11-1
keratin associated protein 11-1
chr1_+_189328246 0.38 ENSRNOT00000084260
Acsm1
acyl-CoA synthetase medium-chain family member 1
chr1_-_224698514 0.29 ENSRNOT00000024234
Slc22a25
solute carrier family 22, member 25
chr10_+_86399827 0.25 ENSRNOT00000009299
Grb7
growth factor receptor bound protein 7
chr5_-_58106706 0.21 ENSRNOT00000019561
Dctn3
dynactin subunit 3
chr8_-_36720810 0.06 ENSRNOT00000089745
Gm1113
predicted gene 1113

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb12

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.2 GO:0015942 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) formamide metabolic process(GO:0043606)
3.7 22.0 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
3.1 9.3 GO:0070634 transepithelial ammonium transport(GO:0070634)
2.4 9.6 GO:0071802 negative regulation of podosome assembly(GO:0071802)
1.5 18.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
1.4 4.3 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
1.3 10.5 GO:0001661 conditioned taste aversion(GO:0001661)
1.3 9.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
1.2 3.5 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
1.0 8.0 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.9 4.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.8 3.3 GO:0097069 cellular response to thyroxine stimulus(GO:0097069)
0.7 5.5 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.6 4.5 GO:0030035 microspike assembly(GO:0030035)
0.6 9.7 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.6 19.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.5 23.4 GO:0000266 mitochondrial fission(GO:0000266)
0.4 1.8 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.4 2.5 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.4 3.1 GO:0061193 taste bud development(GO:0061193)
0.4 5.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.4 14.4 GO:0042073 intraciliary transport(GO:0042073)
0.3 4.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.3 9.4 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.3 8.8 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.3 3.7 GO:0051382 kinetochore assembly(GO:0051382)
0.3 1.7 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.3 0.5 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.3 2.5 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.2 2.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.2 2.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.2 1.9 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 1.4 GO:0090232 positive regulation of spindle checkpoint(GO:0090232) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.1 7.1 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 17.2 GO:0042471 ear morphogenesis(GO:0042471)
0.1 2.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 1.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 10.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 8.5 GO:0014909 smooth muscle cell migration(GO:0014909)
0.1 5.2 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 15.8 GO:0010976 positive regulation of neuron projection development(GO:0010976)
0.0 14.9 GO:0016311 dephosphorylation(GO:0016311)
0.0 7.6 GO:0007204 positive regulation of cytosolic calcium ion concentration(GO:0007204)
0.0 0.3 GO:0015747 urate transport(GO:0015747)
0.0 2.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 5.7 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 5.3 GO:0042278 purine nucleoside metabolic process(GO:0042278)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 11.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
2.1 18.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
1.5 28.9 GO:0001520 outer dense fiber(GO:0001520)
1.1 9.7 GO:0030314 junctional membrane complex(GO:0030314)
1.0 3.1 GO:0045203 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
0.9 4.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.8 17.2 GO:0005922 connexon complex(GO:0005922)
0.6 8.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.6 15.8 GO:0043194 axon initial segment(GO:0043194)
0.6 5.7 GO:0034464 BBSome(GO:0034464)
0.4 15.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.4 3.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.3 4.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.3 12.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.3 23.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.3 8.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.3 3.3 GO:0044294 dendritic growth cone(GO:0044294)
0.2 7.1 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.2 31.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 9.6 GO:0002102 podosome(GO:0002102)
0.2 4.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.2 3.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 12.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 2.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 3.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 5.9 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.9 GO:0005916 fascia adherens(GO:0005916)
0.1 1.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.9 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0010369 chromocenter(GO:0010369)
0.0 4.5 GO:0030027 lamellipodium(GO:0030027)
0.0 7.4 GO:0005874 microtubule(GO:0005874)
0.0 3.1 GO:0043204 perikaryon(GO:0043204)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 18.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
2.2 11.2 GO:0016841 ammonia-lyase activity(GO:0016841)
1.8 9.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
1.5 15.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
1.3 17.0 GO:0003796 lysozyme activity(GO:0003796)
0.8 13.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.7 4.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.5 23.2 GO:0015485 cholesterol binding(GO:0015485)
0.5 5.5 GO:0008131 primary amine oxidase activity(GO:0008131)
0.4 1.8 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.4 9.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.4 3.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.4 4.3 GO:0016004 phospholipase activator activity(GO:0016004)
0.3 2.0 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.3 10.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.3 2.5 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.3 8.0 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.2 3.3 GO:0033691 sialic acid binding(GO:0033691)
0.2 4.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 1.8 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.2 14.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 12.6 GO:0019003 GDP binding(GO:0019003)
0.2 19.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 5.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 4.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 10.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 5.3 GO:0019213 deacetylase activity(GO:0019213)
0.1 23.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.2 GO:0070064 proline-rich region binding(GO:0070064)
0.1 10.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 2.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 1.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 2.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.5 GO:0005113 patched binding(GO:0005113)
0.1 4.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 8.5 GO:0008201 heparin binding(GO:0008201)
0.0 0.4 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 5.2 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 8.5 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 15.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.3 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 9.1 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 3.7 GO:0042393 histone binding(GO:0042393)
0.0 1.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 22.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.4 4.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.4 14.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.3 9.6 PID REELIN PATHWAY Reelin signaling pathway
0.2 7.5 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 3.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 1.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 5.2 PID TNF PATHWAY TNF receptor signaling pathway
0.1 2.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 19.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.2 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 17.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.8 18.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.7 23.2 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.7 10.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.7 15.3 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.4 4.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.3 4.4 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.3 9.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 14.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.2 8.0 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 10.3 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 5.5 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.8 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.1 3.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 8.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 3.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 3.2 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 2.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events