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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Vsx1_Uncx_Prrx2_Shox2_Noto

Z-value: 0.74

Motif logo

Transcription factors associated with Vsx1_Uncx_Prrx2_Shox2_Noto

Gene Symbol Gene ID Gene Info
ENSRNOG00000042220 visual system homeobox 1
ENSRNOG00000001284 UNC homeobox
ENSRNOG00000058329 paired related homeobox 2
ENSRNOG00000012478 short stature homeobox 2
ENSRNOG00000037863 notochord homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Vsx1rn6_v1_chr3_-_146491837_146491837-0.381.8e-12Click!
Prrx2rn6_v1_chr3_+_9681871_9681871-0.164.5e-03Click!
Notorn6_v1_chr4_+_117206355_1172063550.106.7e-02Click!
Shox2rn6_v1_chr2_-_164126783_1641267830.072.2e-01Click!
Uncxrn6_v1_chr12_-_17186679_171866790.019.1e-01Click!

Activity profile of Vsx1_Uncx_Prrx2_Shox2_Noto motif

Sorted Z-values of Vsx1_Uncx_Prrx2_Shox2_Noto motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_53740841 55.47 ENSRNOT00000004295
myosin heavy chain 2
chr7_-_49741540 37.08 ENSRNOT00000006523
myogenic factor 6
chr10_-_87232723 35.12 ENSRNOT00000015150
keratin 25
chr1_+_105284753 32.41 ENSRNOT00000041950
solute carrier family 6 member 5
chr16_+_10267482 29.21 ENSRNOT00000085255
growth differentiation factor 2
chr15_+_1054937 28.87 ENSRNOT00000008154

chr7_-_69982592 28.74 ENSRNOT00000040010
similar to developmental pluripotency associated 5
chr1_+_279633671 23.23 ENSRNOT00000036012
ENSRNOT00000091669
coiled-coil domain containing 172
chr1_+_107344904 21.14 ENSRNOT00000082582
growth arrest-specific 2
chr11_+_58624198 18.57 ENSRNOT00000002091
growth associated protein 43
chr4_-_55011415 18.32 ENSRNOT00000056996
glutamate metabotropic receptor 8
chr9_-_30844199 18.21 ENSRNOT00000017169
collagen type XIX alpha 1 chain
chr13_-_76049363 15.88 ENSRNOT00000075865
ENSRNOT00000007455
BMP/retinoic acid inducible neural specific 2
chr18_+_59748444 15.64 ENSRNOT00000024752
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr10_-_88670430 15.34 ENSRNOT00000025547
hypocretin neuropeptide precursor
chr1_-_173764246 15.27 ENSRNOT00000019690
ENSRNOT00000086944
LIM domain only 1
chr7_+_133856101 15.12 ENSRNOT00000038686
PDZ domain containing RING finger 4
chr10_-_87286387 14.62 ENSRNOT00000044206
keratin 28
chr10_-_87248572 14.49 ENSRNOT00000066637
ENSRNOT00000085677
keratin 26
chr7_-_49732764 13.43 ENSRNOT00000006453
myogenic factor 5
chr7_+_78558701 13.23 ENSRNOT00000006393
regulating synaptic membrane exocytosis 2
chr7_-_143353925 13.01 ENSRNOT00000068533
keratin 71
chr3_+_54253949 12.83 ENSRNOT00000010018
Beta-1,3-galactosyltransferase 1
chr7_-_143408276 12.28 ENSRNOT00000013122
ENSRNOT00000091540
keratin 73
chr8_-_39551700 11.96 ENSRNOT00000091894
ENSRNOT00000076025
PBX/knotted 1 homeobox 2
chr1_+_185863043 11.71 ENSRNOT00000079072
SRY box 6
chr2_+_145174876 11.53 ENSRNOT00000040631
mab-21 like 1
chr9_+_53013413 11.33 ENSRNOT00000005313
ankyrin and armadillo repeat containing
chr1_+_198383201 11.26 ENSRNOT00000037405
seizure related 6 homolog like 2
chr9_-_85243001 11.13 ENSRNOT00000020219
secretogranin II
chr1_+_59156251 11.13 ENSRNOT00000017442
limb and CNS expressed 1
chr13_+_49005405 10.82 ENSRNOT00000092560
ENSRNOT00000076457
LEM domain containing 1
chr8_+_5790034 10.59 ENSRNOT00000061887
matrix metallopeptidase 27
chr3_+_95715193 10.04 ENSRNOT00000089525
paired box 6
chr4_-_172063391 9.80 ENSRNOT00000010158
solute carrier family 15, member 5
chr3_-_165537940 9.57 ENSRNOT00000071119
ENSRNOT00000070964
spalt-like transcription factor 4
chr7_-_143967484 9.31 ENSRNOT00000081758
Sp7 transcription factor
chr12_-_2174131 9.25 ENSRNOT00000001313
Purkinje cell protein 2
chr3_+_47677720 9.08 ENSRNOT00000065340
T-box, brain, 1
chr4_-_80395502 8.61 ENSRNOT00000014437
neuropeptide VF precursor
chr8_+_33239139 8.54 ENSRNOT00000011589
Rho GTPase activating protein 32
chr7_-_143966863 8.35 ENSRNOT00000018828
Sp7 transcription factor
chr5_+_139790395 8.30 ENSRNOT00000015033
regulating synaptic membrane exocytosis 3
chr10_+_54352270 8.22 ENSRNOT00000036752
dehydrogenase/reductase 7C
chr11_+_28780446 8.22 ENSRNOT00000072546
keratin associated protein 15-1
chr10_-_74679858 8.01 ENSRNOT00000003859
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr17_+_11683862 7.74 ENSRNOT00000024766
msh homeobox 2
chr16_+_46731403 7.65 ENSRNOT00000017624
teneurin transmembrane protein 3
chr1_-_276228574 7.64 ENSRNOT00000021746
guanylate cyclase 2G
chr10_-_87521514 7.63 ENSRNOT00000084668
ENSRNOT00000071705
keratin associated protein 2-4-like
chrX_+_118197217 7.20 ENSRNOT00000090922
5-hydroxytryptamine receptor 2C
chr2_-_192027225 7.09 ENSRNOT00000016430
proline rich 9
chr18_-_13183263 6.74 ENSRNOT00000050933
coiled-coil domain containing 178
chr16_+_22361998 6.71 ENSRNOT00000016193
solute carrier family 18 member A1
chr14_+_96499520 6.64 ENSRNOT00000074692

chr2_+_196334626 6.49 ENSRNOT00000050914
ENSRNOT00000028645
ENSRNOT00000090729
semaphorin 6C
chr10_-_87468711 6.37 ENSRNOT00000039983
keratin associated protein 3-3
chr7_+_143122269 6.22 ENSRNOT00000082542
ENSRNOT00000045495
ENSRNOT00000081386
ENSRNOT00000067422
keratin 86
chr19_+_39229754 6.19 ENSRNOT00000050612
vacuolar protein sorting 4 homolog A
chr7_+_44009069 6.15 ENSRNOT00000005523
MGAT4 family, member C
chr14_-_2032593 6.08 ENSRNOT00000000037
fibroblast growth factor receptor-like 1
chr3_-_37803112 5.85 ENSRNOT00000059461
nebulin
chr14_+_42714315 5.74 ENSRNOT00000084095
ENSRNOT00000091449
paired-like homeobox 2b
chr8_+_49441106 5.63 ENSRNOT00000030152
sodium voltage-gated channel beta subunit 4
chr16_-_24951612 5.60 ENSRNOT00000018987
transketolase-like 2
chr9_-_53315915 5.50 ENSRNOT00000038093
myostatin
chr2_+_136993208 5.43 ENSRNOT00000040187
ENSRNOT00000066542
protocadherin 10
chr16_+_29674793 5.30 ENSRNOT00000059724
annexin A10
chr2_-_98610368 5.13 ENSRNOT00000011641
zinc finger homeobox 4
chr7_-_126382449 5.10 ENSRNOT00000085540
RIKEN cDNA 7530416G11 gene
chrX_-_23144324 5.09 ENSRNOT00000000178
ENSRNOT00000081239
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr3_-_15278645 5.03 ENSRNOT00000032204
tubulin tyrosine ligase like11
chr12_-_47142852 5.01 ENSRNOT00000001591
POP5 homolog, ribonuclease P/MRP subunit
chr6_-_23316962 4.82 ENSRNOT00000065421
CAP-GLY domain containing linker protein family, member 4
chr8_+_48718329 4.69 ENSRNOT00000089763
solute carrier family 37 member 4
chr3_-_52447622 4.66 ENSRNOT00000083552
sodium voltage-gated channel alpha subunit 1
chr9_+_25304876 4.65 ENSRNOT00000065053
transcription factor AP-2 delta
chr8_-_83280888 4.64 ENSRNOT00000052341
GDNF family receptor alpha like
chr6_+_28382962 4.60 ENSRNOT00000016976
proopiomelanocortin
chr17_-_39824299 4.59 ENSRNOT00000023412
prolactin
chr2_-_188559882 4.46 ENSRNOT00000088199
tripartite motif-containing 46
chr5_-_28131133 4.29 ENSRNOT00000067331
solute carrier family 26 member 7
chrX_-_110232179 4.26 ENSRNOT00000014739
serpin family A member 7
chr1_-_104973648 4.23 ENSRNOT00000019739
developing brain homeobox 1
chr10_-_88000423 4.21 ENSRNOT00000076787
ENSRNOT00000046751
ENSRNOT00000091394
keratin 32
chr11_+_80742467 4.19 ENSRNOT00000002507
mannan-binding lectin serine peptidase 1
chr17_-_79829511 4.19 ENSRNOT00000085909

chr6_-_67084234 4.16 ENSRNOT00000050372
NOVA alternative splicing regulator 1
chr16_+_2634603 4.16 ENSRNOT00000019113
HESX homeobox 1
chr5_-_28130803 4.15 ENSRNOT00000093186
solute carrier family 26 member 7
chr6_-_106971250 4.13 ENSRNOT00000010926
double PHD fingers 3
chr12_-_17186679 4.09 ENSRNOT00000001730
UNC homeobox
chr2_+_18354542 4.02 ENSRNOT00000042958
hyaluronan and proteoglycan link protein 1
chr8_-_14373894 4.00 ENSRNOT00000011883
melatonin receptor 1B
chr10_+_103395511 3.95 ENSRNOT00000004256
G protein-coupled receptor, class C, group 5, member C
chr7_+_136182224 3.85 ENSRNOT00000008159
transmembrane protein 117
chr13_+_90943255 3.78 ENSRNOT00000011539
V-set and immunoglobulin domain containing 8
chr3_+_61620192 3.76 ENSRNOT00000065426
homeo box D9
chr11_-_76888178 3.68 ENSRNOT00000049841
osteocrin
chr2_+_54466280 3.53 ENSRNOT00000033112
complement C6
chr15_-_27819376 3.51 ENSRNOT00000067400
RIKEN cDNA A930018M24 gene
chr14_+_23405717 3.50 ENSRNOT00000029805
transmembrane protease, serine 11C
chr11_-_28777603 3.50 ENSRNOT00000002132
keratin associated protein 14
chr3_-_44086006 3.48 ENSRNOT00000034449
ENSRNOT00000082604
ermin
chr4_-_41212072 3.48 ENSRNOT00000085596
protein phosphatase 1, regulatory subunit 3A
chr9_-_14550625 3.39 ENSRNOT00000078227
O-acyl-ADP-ribose deacylase 1
chr7_+_2752680 3.38 ENSRNOT00000033726
citrate synthase
chr9_+_73378057 3.36 ENSRNOT00000043627
ENSRNOT00000045766
ENSRNOT00000092445
ENSRNOT00000037974
microtubule-associated protein 2
chrX_+_131381134 3.33 ENSRNOT00000007474

chr2_-_139528162 3.26 ENSRNOT00000014317
solute carrier family 7 member 11
chr4_-_180234804 3.09 ENSRNOT00000070957
basic helix-loop-helix family, member e41
chr5_-_12526962 3.07 ENSRNOT00000092104
suppression of tumorigenicity 18
chr4_-_4473307 3.07 ENSRNOT00000045773
dipeptidyl peptidase like 6
chr10_+_91217079 3.05 ENSRNOT00000004218
hexamethylene bis-acetamide inducible 2
chr8_-_43304560 3.03 ENSRNOT00000060092
olfactory receptor 1307
chr14_+_23330933 3.02 ENSRNOT00000088552
transmembrane protease, serine 11d
chr17_-_45746753 2.96 ENSRNOT00000077475
similar to brain Zn-finger protein
chr1_+_184301493 2.96 ENSRNOT00000078096
inscuteable homolog (Drosophila)
chr6_-_36876805 2.92 ENSRNOT00000006482
mesogenin 1
chr10_-_87503591 2.87 ENSRNOT00000037980
keratin associated protein 1-1
chr19_-_49448072 2.87 ENSRNOT00000014997
C-x(9)-C motif containing 2
chr4_-_169036950 2.83 ENSRNOT00000011295
germ cell associated 1
chr7_-_145062956 2.79 ENSRNOT00000055274
similar to CDNA sequence BC048502
chr2_-_170301348 2.77 ENSRNOT00000088131
sucrase-isomaltase
chr3_+_5709236 2.76 ENSRNOT00000061201
ENSRNOT00000070887
dopamine beta-hydroxylase
chr4_-_58250798 2.68 ENSRNOT00000048436
Kruppel-like factor 14
chr9_+_73418607 2.64 ENSRNOT00000092547
microtubule-associated protein 2
chr16_-_9658484 2.61 ENSRNOT00000065216
mitogen-activated protein kinase 8
chr1_+_101599018 2.54 ENSRNOT00000028494
fucosyltransferase 1
chr3_-_11452529 2.53 ENSRNOT00000020206
solute carrier family 25 member 25
chr4_+_147832136 2.51 ENSRNOT00000064603
rhodopsin
chr11_-_29710849 2.47 ENSRNOT00000029345
keratin associated protein 11-1
chr4_+_57925323 2.46 ENSRNOT00000085798
carboxypeptidase A5
chr11_-_43022565 2.44 ENSRNOT00000002285
ribosomal oxygenase 2
chr1_+_140998240 2.38 ENSRNOT00000023506
ENSRNOT00000090897
abhydrolase domain containing 2
chr3_-_141411170 2.34 ENSRNOT00000017364
NK2 homeobox 2
chr5_-_136965191 2.32 ENSRNOT00000056842
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
chr2_-_45518502 2.28 ENSRNOT00000014627
heat shock protein family B (small) member 3
chr8_-_84506328 2.26 ENSRNOT00000064754
muscular LMNA-interacting protein
chr7_-_106653567 2.15 ENSRNOT00000042522
otoconin 90
chr8_+_40410604 2.14 ENSRNOT00000049392
olfactory receptor 1202
chr4_+_1671269 2.14 ENSRNOT00000071452
olfactory receptor 1251
chr4_+_180291389 2.13 ENSRNOT00000002465
sarcospan
chr10_-_93675991 2.12 ENSRNOT00000090662
membrane associated ring-CH-type finger 10
chr9_+_95398237 2.11 ENSRNOT00000025879
transient receptor potential cation channel, subfamily M, member 8
chr9_-_82146874 2.11 ENSRNOT00000024190
FEV, ETS transcription factor
chr8_+_122076759 2.08 ENSRNOT00000012545
cytoplasmic linker associated protein 2
chr2_+_144861455 2.02 ENSRNOT00000093284
ENSRNOT00000019748
ENSRNOT00000072110
doublecortin-like kinase 1
chr14_+_7630482 2.01 ENSRNOT00000091581
similar to hypothetical protein MGC26744
chr15_+_11298478 1.99 ENSRNOT00000007672
leucine rich repeat containing 3B
chr14_+_4362717 1.97 ENSRNOT00000002887
BarH-like homeobox 2
chr1_-_48033343 1.92 ENSRNOT00000019531
ENSRNOT00000076422
t-complex 1
chr4_+_2055615 1.91 ENSRNOT00000007646
ring finger protein 32
chr18_-_61057365 1.89 ENSRNOT00000042352
alpha-kinase 2
chr9_-_18371856 1.88 ENSRNOT00000027293
SPT3 homolog, SAGA and STAGA complex component
chr6_+_22696397 1.87 ENSRNOT00000011630
anaplastic lymphoma receptor tyrosine kinase
chrX_+_6273733 1.86 ENSRNOT00000074275
NDP, norrin cystine knot growth factor
chr1_-_167971151 1.86 ENSRNOT00000043023
olfactory receptor 53
chr2_+_189993262 1.84 ENSRNOT00000016034
S100 calcium binding protein A3
chr12_-_29743705 1.82 ENSRNOT00000001185
calneuron 1
chr13_-_36290531 1.82 ENSRNOT00000071388
STEAP3 metalloreductase
chr10_+_87782376 1.78 ENSRNOT00000017415
hypothetical protein LOC680396
chrX_-_16532089 1.75 ENSRNOT00000093156
diacylglycerol kinase kappa
chrX_-_156589907 1.75 ENSRNOT00000083147
opsin 1 (cone pigments), medium-wave-sensitive
chr15_+_12827707 1.72 ENSRNOT00000012452
Fez family zinc finger 2
chr3_+_9403840 1.72 ENSRNOT00000071380
pyroglutamylated RFamide peptide
chr10_+_16259728 1.69 ENSRNOT00000028115
biorientation of chromosomes in cell division 1
chr2_+_18392142 1.69 ENSRNOT00000043196
hyaluronan and proteoglycan link protein 1
chr5_+_135574172 1.68 ENSRNOT00000023416
testis-specific kinase 2
chr2_-_61692487 1.66 ENSRNOT00000078544
LRRGT00045
chr8_-_53223804 1.65 ENSRNOT00000008965
5-hydroxytryptamine receptor 3A
chr5_+_36566783 1.63 ENSRNOT00000077650
F-box and leucine-rich repeat protein 4
chr11_-_4397361 1.63 ENSRNOT00000046370
cell adhesion molecule 2
chr12_-_35979193 1.60 ENSRNOT00000071104
transmembrane protein 132B
chr4_+_108301129 1.59 ENSRNOT00000007993
leucine rich repeat transmembrane neuronal 1
chr20_-_30947484 1.58 ENSRNOT00000065614
phosphatase domain containing, paladin 1
chr6_+_49825469 1.53 ENSRNOT00000006921
family with sequence similarity 150, member B
chr2_-_173087648 1.49 ENSRNOT00000091079
IQ motif containing J
chr10_+_64930023 1.43 ENSRNOT00000071102

chr3_-_61636038 1.42 ENSRNOT00000086887

chr18_+_81694808 1.41 ENSRNOT00000020446
cytochrome b5 type A
chr3_-_10196626 1.40 ENSRNOT00000012234
PR/SET domain 12
chr13_+_91054974 1.40 ENSRNOT00000091089
C-reactive protein
chr8_+_41350182 1.40 ENSRNOT00000072823
olfactory receptor 143-like
chr3_-_77605962 1.39 ENSRNOT00000090062
olfactory receptor 665
chr1_-_230687157 1.39 ENSRNOT00000048193
olfactory receptor 380
chr14_-_21252538 1.38 ENSRNOT00000005003
ameloblastin
chr11_-_28900376 1.37 ENSRNOT00000061606
keratin associated protein 16-5
chr20_-_3728844 1.36 ENSRNOT00000074958
psoriasis susceptibility 1 candidate 2
chr9_-_79630452 1.35 ENSRNOT00000078125
ENSRNOT00000086044
ENSRNOT00000089283
peroxisomal trans-2-enoyl-CoA reductase
chr15_+_4064706 1.35 ENSRNOT00000011956
synaptopodin 2-like
chr4_+_68656928 1.35 ENSRNOT00000016232
taste receptor, type 2, member 108
chr1_+_80141630 1.32 ENSRNOT00000029552
optic atrophy 3
chr1_+_264741911 1.28 ENSRNOT00000019956
semaphorin 4G
chr5_-_168734296 1.28 ENSRNOT00000066120
calmodulin binding transcription activator 1
chr4_-_10995792 1.25 ENSRNOT00000078733

chr6_+_2216623 1.20 ENSRNOT00000008045
regulator of microtubule dynamics 2
chr10_-_87753668 1.18 ENSRNOT00000066758
ENSRNOT00000047104
keratin associated protein 4-3
chr15_-_26939911 1.18 ENSRNOT00000016683
olfactory receptor 1630
chr4_+_1658278 1.14 ENSRNOT00000073845
olfactory receptor 1250

Network of associatons between targets according to the STRING database.

First level regulatory network of Vsx1_Uncx_Prrx2_Shox2_Noto

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 32.4 GO:0036233 glycine import(GO:0036233)
6.3 50.5 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
5.2 15.6 GO:1990743 protein sialylation(GO:1990743)
4.3 55.5 GO:0001778 plasma membrane repair(GO:0001778)
3.8 15.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
3.3 10.0 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
2.9 5.7 GO:0021550 medulla oblongata development(GO:0021550)
2.8 14.1 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
2.6 7.7 GO:2001055 embryonic nail plate morphogenesis(GO:0035880) positive regulation of mesenchymal cell apoptotic process(GO:2001055)
2.4 19.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
2.4 7.2 GO:0031583 phospholipase D-activating G-protein coupled receptor signaling pathway(GO:0031583)
2.1 6.2 GO:1903774 multivesicular body assembly(GO:0036258) positive regulation of viral budding via host ESCRT complex(GO:1903774)
1.9 18.6 GO:0016198 axon choice point recognition(GO:0016198)
1.8 48.1 GO:0045109 intermediate filament organization(GO:0045109)
1.7 18.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
1.6 12.7 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
1.5 10.8 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.3 6.7 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.2 24.8 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
1.2 3.7 GO:1903860 negative regulation of dendrite extension(GO:1903860)
1.2 3.5 GO:0001905 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
1.1 4.2 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
1.0 13.2 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
1.0 11.2 GO:0097264 self proteolysis(GO:0097264)
0.9 2.8 GO:0006589 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.9 12.8 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.9 2.6 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.9 18.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.8 8.6 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.7 4.2 GO:0030916 otic vesicle formation(GO:0030916)
0.7 4.7 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.7 4.6 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.6 5.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.6 1.9 GO:0090648 response to environmental enrichment(GO:0090648)
0.6 1.8 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.5 8.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.5 3.2 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.5 10.0 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.5 4.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.5 6.1 GO:0060539 diaphragm development(GO:0060539)
0.5 5.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.5 9.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.5 8.4 GO:0019532 oxalate transport(GO:0019532) sulfate transmembrane transport(GO:1902358)
0.5 1.9 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.5 9.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.5 1.4 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.5 1.4 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.4 4.2 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.4 2.1 GO:0050955 thermoception(GO:0050955)
0.4 4.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.4 4.2 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.4 4.7 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3 1.0 GO:1901367 response to L-cysteine(GO:1901367)
0.3 5.6 GO:0086016 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.3 1.9 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.3 4.5 GO:0099612 protein localization to axon(GO:0099612)
0.3 3.1 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.3 2.5 GO:0015866 ADP transport(GO:0015866)
0.3 5.3 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.3 8.3 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.3 2.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 2.4 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.2 1.0 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.2 1.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 0.9 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.2 1.6 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.2 2.8 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.2 2.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 2.9 GO:0007379 segment specification(GO:0007379)
0.2 3.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.2 0.8 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.2 1.1 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.2 2.5 GO:0036065 fucosylation(GO:0036065)
0.2 6.0 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.2 2.7 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.2 0.5 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.2 1.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.2 3.4 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 3.0 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.1 2.3 GO:0097503 sialylation(GO:0097503)
0.1 10.6 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 3.0 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.1 2.8 GO:0007625 grooming behavior(GO:0007625)
0.1 0.5 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.1 3.8 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.1 1.0 GO:0014029 neural crest formation(GO:0014029)
0.1 2.4 GO:0048240 sperm capacitation(GO:0048240)
0.1 1.9 GO:0048665 neuron fate specification(GO:0048665)
0.1 0.6 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.1 1.7 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 1.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 2.3 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.1 3.1 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.9 GO:0001302 replicative cell aging(GO:0001302)
0.1 0.9 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.1 3.1 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 2.0 GO:0001709 cell fate determination(GO:0001709)
0.1 0.5 GO:0046836 glycolipid transport(GO:0046836)
0.1 5.0 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 2.1 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 0.3 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.2 GO:1900244 positive regulation of synaptic vesicle endocytosis(GO:1900244)
0.1 1.2 GO:0016578 histone deubiquitination(GO:0016578)
0.1 1.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.3 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 8.2 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 1.4 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 1.4 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.4 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 1.1 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.8 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 1.6 GO:0032414 positive regulation of ion transmembrane transporter activity(GO:0032414)
0.0 1.7 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.0 0.1 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 4.5 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.0 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.3 GO:1902745 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 17.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.4 GO:0031214 biomineral tissue development(GO:0031214)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.2 55.5 GO:0005826 actomyosin contractile ring(GO:0005826)
2.7 8.2 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
2.3 18.6 GO:0032584 growth cone membrane(GO:0032584)
1.5 10.6 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.9 4.5 GO:1990769 proximal neuron projection(GO:1990769)
0.9 6.2 GO:0090543 Flemming body(GO:0090543)
0.8 5.0 GO:0005655 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.8 121.6 GO:0005882 intermediate filament(GO:0005882)
0.7 11.1 GO:0031045 dense core granule(GO:0031045)
0.7 2.8 GO:0042584 secretory granule lumen(GO:0034774) chromaffin granule membrane(GO:0042584)
0.7 6.0 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.6 3.5 GO:0033269 internode region of axon(GO:0033269)
0.5 10.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.4 21.5 GO:0048786 presynaptic active zone(GO:0048786)
0.4 18.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.3 2.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.3 0.9 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.3 7.1 GO:0001533 cornified envelope(GO:0001533)
0.3 2.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.3 4.1 GO:0071565 nBAF complex(GO:0071565)
0.3 12.6 GO:0045171 intercellular bridge(GO:0045171)
0.2 2.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 16.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 12.0 GO:0042734 presynaptic membrane(GO:0042734)
0.1 1.9 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 0.4 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 1.9 GO:0030914 STAGA complex(GO:0030914)
0.1 1.0 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 9.9 GO:0000792 heterochromatin(GO:0000792)
0.1 0.5 GO:0071438 invadopodium membrane(GO:0071438)
0.1 6.1 GO:0044291 cell-cell contact zone(GO:0044291)
0.1 1.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.9 GO:0016235 aggresome(GO:0016235)
0.1 2.6 GO:0002102 podosome(GO:0002102)
0.1 1.8 GO:0005771 multivesicular body(GO:0005771)
0.1 3.0 GO:0030426 growth cone(GO:0030426)
0.1 1.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 6.9 GO:0001650 fibrillar center(GO:0001650)
0.0 1.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 1.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.4 GO:0060170 ciliary membrane(GO:0060170)
0.0 4.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 3.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.7 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 7.8 GO:0098793 presynapse(GO:0098793)
0.0 0.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 20.0 GO:0005730 nucleolus(GO:0005730)
0.0 2.3 GO:0016605 PML body(GO:0016605)
0.0 12.4 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.7 GO:0044438 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 5.1 GO:0044445 cytosolic part(GO:0044445)
0.0 1.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 5.7 GO:0016607 nuclear speck(GO:0016607)
0.0 3.9 GO:0043235 receptor complex(GO:0043235)
0.0 3.7 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.4 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.1 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 1.2 GO:0000922 spindle pole(GO:0000922)
0.0 3.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.8 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
11.9 35.7 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
5.2 15.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
4.8 19.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
4.6 18.3 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
2.6 12.8 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
2.2 6.7 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
1.3 4.0 GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding(GO:0071886)
1.1 4.6 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
1.1 14.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
1.0 10.0 GO:0003680 AT DNA binding(GO:0003680)
0.9 2.8 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.9 2.8 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.8 2.5 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.8 4.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.8 4.6 GO:0005148 prolactin receptor binding(GO:0005148)
0.8 6.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.7 5.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.7 5.6 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.7 3.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.7 4.7 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.6 18.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.6 2.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.6 8.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.6 30.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.5 4.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.5 4.6 GO:0009881 photoreceptor activity(GO:0009881)
0.5 5.0 GO:0004526 ribonuclease P activity(GO:0004526)
0.5 2.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.5 1.8 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.4 3.1 GO:0043426 MRF binding(GO:0043426)
0.4 3.0 GO:0097322 7SK snRNA binding(GO:0097322)
0.4 12.0 GO:0003785 actin monomer binding(GO:0003785)
0.4 6.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.4 8.0 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.4 8.1 GO:0002162 dystroglycan binding(GO:0002162)
0.3 1.4 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.3 1.4 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.3 39.9 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.3 2.6 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.3 1.0 GO:0003921 GMP synthase activity(GO:0003921) GMP synthase (glutamine-hydrolyzing) activity(GO:0003922)
0.3 3.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.3 7.8 GO:0042056 chemoattractant activity(GO:0042056)
0.3 1.1 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.3 2.5 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.2 6.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 4.7 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.2 1.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 1.0 GO:0043532 angiostatin binding(GO:0043532)
0.2 2.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.6 GO:0051378 serotonin binding(GO:0051378)
0.1 0.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.6 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.5 GO:0017089 glycolipid transporter activity(GO:0017089)
0.1 7.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 82.7 GO:0005198 structural molecule activity(GO:0005198)
0.1 6.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.5 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.1 4.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 2.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 30.4 GO:0003779 actin binding(GO:0003779)
0.1 12.0 GO:0044325 ion channel binding(GO:0044325)
0.1 21.1 GO:0008017 microtubule binding(GO:0008017)
0.1 5.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 3.4 GO:0019213 deacetylase activity(GO:0019213)
0.1 1.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 14.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 8.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 1.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 2.3 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.1 1.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.7 GO:0008527 taste receptor activity(GO:0008527)
0.0 1.3 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0 0.3 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 1.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 6.1 GO:0016758 transferase activity, transferring hexosyl groups(GO:0016758)
0.0 0.9 GO:0030145 manganese ion binding(GO:0030145)
0.0 4.8 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 15.3 GO:0044212 transcription regulatory region DNA binding(GO:0044212)
0.0 5.0 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.0 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 4.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.8 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 2.1 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 6.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 22.6 GO:0003723 RNA binding(GO:0003723)
0.0 2.1 GO:0016874 ligase activity(GO:0016874)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 17.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.7 GO:0051082 unfolded protein binding(GO:0051082)
0.0 7.6 GO:0008270 zinc ion binding(GO:0008270)
0.0 1.2 GO:0003713 transcription coactivator activity(GO:0003713)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 55.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.9 29.2 PID ALK1 PATHWAY ALK1 signaling events
0.5 21.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.4 18.2 NABA COLLAGENS Genes encoding collagen proteins
0.3 21.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.3 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.3 4.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.3 24.6 PID CMYB PATHWAY C-MYB transcription factor network
0.2 17.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.2 3.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 9.3 PID CDC42 PATHWAY CDC42 signaling events
0.1 6.0 PID LKB1 PATHWAY LKB1 signaling events
0.1 4.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 2.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 6.2 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 3.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.8 PID MYC PATHWAY C-MYC pathway
0.1 4.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 0.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 3.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 9.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 39.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
1.3 46.6 REACTOME MYOGENESIS Genes involved in Myogenesis
1.3 21.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.8 18.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.7 21.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.7 10.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.6 4.6 REACTOME OPSINS Genes involved in Opsins
0.5 5.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.5 5.1 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.5 2.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.3 18.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.3 4.0 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.3 4.0 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.3 6.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2 4.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 2.6 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.2 3.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 2.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 3.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 5.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 5.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 3.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.9 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 4.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 1.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 13.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 0.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.8 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.1 1.0 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.6 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 1.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 2.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events