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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Ubp1

Z-value: 0.88

Motif logo

Transcription factors associated with Ubp1

Gene Symbol Gene ID Gene Info
ENSRNOG00000009729 upstream binding protein 1 (LBP-1a)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ubp1rn6_v1_chr8_+_122197027_1221970270.262.7e-06Click!

Activity profile of Ubp1 motif

Sorted Z-values of Ubp1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_98457810 28.96 ENSRNOT00000074175

chr7_+_120153184 22.81 ENSRNOT00000013538
galectin 1
chr4_+_98370797 21.27 ENSRNOT00000031991

chr2_+_223029559 20.56 ENSRNOT00000045584

chr11_+_86092468 20.43 ENSRNOT00000057971
lambda-chain C1-region-like
chrX_+_28539158 19.16 ENSRNOT00000073535
toll-like receptor 8
chr3_+_19274273 18.19 ENSRNOT00000040102

chr4_+_106323089 17.38 ENSRNOT00000091402

chr1_-_227441442 17.12 ENSRNOT00000028433
membrane spanning 4-domains A1
chr3_-_2853272 16.62 ENSRNOT00000023022
ficolin A
chr6_-_138508753 16.41 ENSRNOT00000006888
immunoglobulin heavy constant mu
chr4_+_69403735 15.96 ENSRNOT00000082012
T cell receptor beta, variable 13-1
chr4_+_14151343 15.90 ENSRNOT00000061687
ENSRNOT00000076573
ENSRNOT00000077219
ENSRNOT00000008319
CD36 molecule
chr3_-_17081510 15.78 ENSRNOT00000063862

chr3_-_16752353 15.37 ENSRNOT00000046489

chr4_-_103258134 14.05 ENSRNOT00000086827

chr6_-_125723944 13.83 ENSRNOT00000007004
fibulin 5
chr3_+_17107861 13.56 ENSRNOT00000043097

chr15_+_57241968 13.39 ENSRNOT00000082191
lymphocyte cytosolic protein 1
chr10_+_45258887 13.36 ENSRNOT00000048642
butyrophilin like 10
chr4_+_70828894 12.73 ENSRNOT00000064892
T cell receptor beta, constant 2
chr6_-_142060032 12.62 ENSRNOT00000064717

chr5_+_173288447 12.24 ENSRNOT00000091205
ENSRNOT00000067252
matrix remodeling associated 8
chr3_+_17139670 12.16 ENSRNOT00000073316

chr4_-_98305173 11.71 ENSRNOT00000010151
interleukin 23 receptor
chr3_+_19174027 11.60 ENSRNOT00000074445

chr2_-_60683451 11.06 ENSRNOT00000046215
retinoic acid induced 14
chr8_+_49282460 11.05 ENSRNOT00000021488
CD3d molecule
chr1_+_199555722 10.90 ENSRNOT00000054983
integrin subunit alpha X
chr5_+_144308611 10.80 ENSRNOT00000014388
collagen type VIII alpha 2 chain
chr20_-_32353677 10.65 ENSRNOT00000035355
storkhead box 1
chr8_+_55603968 10.58 ENSRNOT00000066848
POU class 2 associating factor 1
chr3_+_20375699 10.58 ENSRNOT00000088492

chr6_-_143195143 10.53 ENSRNOT00000081337

chr6_-_125723732 10.43 ENSRNOT00000084815
fibulin 5
chr6_-_142993147 10.36 ENSRNOT00000044381
mCG1038839-like
chr1_-_73682247 10.23 ENSRNOT00000079498
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr3_+_17180411 10.20 ENSRNOT00000058260

chr7_-_18793289 10.11 ENSRNOT00000036375

chr8_-_125544427 10.02 ENSRNOT00000041548
ENSRNOT00000039904
ENSRNOT00000036642
RNA binding motif, single stranded interacting protein 3
chr3_-_14643897 9.92 ENSRNOT00000082008
ENSRNOT00000025983
glycoprotein, alpha-galactosyltransferase 1
chr3_-_110517163 9.70 ENSRNOT00000078037
phospholipase C, beta 2
chr5_-_79691258 9.56 ENSRNOT00000072920
tumor necrosis factor superfamily member 8
chr9_-_14668297 9.52 ENSRNOT00000042404
triggering receptor expressed on myeloid cells-like 2
chr6_-_141488290 9.31 ENSRNOT00000067336

chr12_+_19714324 9.30 ENSRNOT00000072303
similar to cell surface receptor FDFACT
chr19_-_10976396 9.25 ENSRNOT00000073239
NLR family, CARD domain containing 5
chr3_+_16817051 9.09 ENSRNOT00000071666

chr4_+_14109864 9.06 ENSRNOT00000076349
similar to fatty acid translocase/CD36
chr6_-_139997537 9.06 ENSRNOT00000073207

chr3_-_20695952 9.01 ENSRNOT00000072306

chr15_-_34603819 8.91 ENSRNOT00000067539
chymase 1
chr17_+_15814132 8.87 ENSRNOT00000032997
sushi domain containing 3
chr4_-_163227242 8.83 ENSRNOT00000091552
ENSRNOT00000077793
C-type lectin domain family 7, member A
chr3_-_20479999 8.81 ENSRNOT00000050573

chr12_-_20486276 8.80 ENSRNOT00000074057
similar to paired immunoglobin-like type 2 receptor beta
chr12_+_25498198 8.68 ENSRNOT00000076916
neutrophil cytosolic factor 1
chr10_-_56506446 8.53 ENSRNOT00000021357
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr3_+_19441604 8.48 ENSRNOT00000090581

chr4_+_90990088 8.39 ENSRNOT00000030320
multimerin 1
chr14_-_17225389 8.30 ENSRNOT00000052035
ADP-ribosyltransferase 3
chr4_+_144192989 8.22 ENSRNOT00000007523
LIM and cysteine-rich domains 1
chr3_+_16495748 8.19 ENSRNOT00000045492

chrX_-_1346181 8.19 ENSRNOT00000042736
60S ribosomal protein L12-like
chr12_+_48577905 8.17 ENSRNOT00000000888
selectin P ligand
chr6_-_142372031 8.09 ENSRNOT00000063929

chr9_+_92618352 8.02 ENSRNOT00000034603
SP140 nuclear body protein
chr4_-_70996395 8.00 ENSRNOT00000021485
Kell blood group, metallo-endopeptidase
chr6_-_140880070 7.99 ENSRNOT00000073779
uncharacterized LOC691828
chr8_-_63092009 7.97 ENSRNOT00000034300
lysyl oxidase-like 1
chr1_+_47231093 7.91 ENSRNOT00000024967
synaptotagmin-like 3
chr4_+_179398621 7.87 ENSRNOT00000049474
ENSRNOT00000067506
lymphoid-restricted membrane protein
chr1_-_101236065 7.86 ENSRNOT00000066834
CD37 molecule
chr6_-_140642221 7.86 ENSRNOT00000081996

chr3_-_20419417 7.84 ENSRNOT00000077772

chr10_-_63491279 7.65 ENSRNOT00000082301
tumor suppressor candidate 5
chr1_-_213650247 7.64 ENSRNOT00000019679
cytochrome c oxidase, subunit VIIIb
chr10_+_12046701 7.59 ENSRNOT00000011073
ENSRNOT00000084004
MEFV, pyrin innate immunity regulator
chr8_+_117694605 7.57 ENSRNOT00000027994
collagen type VII alpha 1 chain
chr5_+_133865331 7.56 ENSRNOT00000035409
TAL bHLH transcription factor 1, erythroid differentiation factor
chr15_-_34612432 7.53 ENSRNOT00000090206
mast cell protease 1-like 1
chr6_-_75874235 7.46 ENSRNOT00000009080
bromodomain adjacent to zinc finger domain, 1A
chr19_+_24456976 7.45 ENSRNOT00000004900
uncoupling protein 1
chr2_-_149325913 7.45 ENSRNOT00000036690
G protein-coupled receptor 171
chr4_+_101909389 7.43 ENSRNOT00000086458

chr7_-_29152442 7.42 ENSRNOT00000079774
myosin binding protein C, slow type
chr14_-_18849258 7.40 ENSRNOT00000033406
platelet factor 4
chr17_-_54808483 7.32 ENSRNOT00000075683

chr11_+_17538063 7.23 ENSRNOT00000031889
ENSRNOT00000090878
chondrolectin
chr16_-_48437223 7.17 ENSRNOT00000013005
ENSRNOT00000059401
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr8_-_133128290 7.15 ENSRNOT00000008783
chemokine (C-C motif) receptor 1-like 1
chr7_+_144623555 7.13 ENSRNOT00000022217
homeo box C6
chr4_-_145390447 6.96 ENSRNOT00000091965
ENSRNOT00000012136
cell death-inducing DFFA-like effector c
chrX_-_105390580 6.94 ENSRNOT00000077547
Bruton tyrosine kinase
chr6_-_141062581 6.94 ENSRNOT00000073446

chr6_-_143131118 6.90 ENSRNOT00000074930

chr1_+_168957460 6.87 ENSRNOT00000090745
hemoglobin subunit beta-2
chr10_+_45893018 6.79 ENSRNOT00000004280
ENSRNOT00000086710
NLR family, pyrin domain containing 3
chr4_-_156276304 6.78 ENSRNOT00000078725
C-type lectin domain family 4, member E
chr6_-_140485913 6.76 ENSRNOT00000048463

chr19_-_39267928 6.68 ENSRNOT00000027686
transmembrane p24 trafficking protein 6
chr10_-_75171774 6.64 ENSRNOT00000011735
eosinophil peroxidase
chr15_+_32817343 6.64 ENSRNOT00000073853

chr12_-_21362205 6.52 ENSRNOT00000064787
paired immunoglobulin-like type 2 receptor beta-2
chr4_+_44597123 6.49 ENSRNOT00000078250
caveolin 1
chr9_+_67774150 6.48 ENSRNOT00000091060
inducible T-cell co-stimulator
chr4_+_78694447 6.44 ENSRNOT00000011945
glycoprotein nmb
chr12_-_21670269 6.43 ENSRNOT00000074863
paired immunoglobulin-like type 2 receptor alpha-like
chr14_-_72122158 6.33 ENSRNOT00000064495
C1q and tumor necrosis factor related protein 7
chr7_-_12424367 6.32 ENSRNOT00000060698
midnolin
chr20_-_3374344 6.30 ENSRNOT00000082999
protein phosphatase 1, regulatory subunit 18
chr10_+_88326337 6.30 ENSRNOT00000022029
ENSRNOT00000076461
FK506 binding protein 10
chr6_-_138640187 6.28 ENSRNOT00000087983

chr15_+_57221292 6.26 ENSRNOT00000014502
lymphocyte cytosolic protein 1
chr4_+_69457472 6.26 ENSRNOT00000067597
T cell receptor beta, variable 19
chr4_+_14070553 6.25 ENSRNOT00000077505
CD36 molecule
chrX_+_71174699 6.20 ENSRNOT00000076957
ENSRNOT00000090192
ENSRNOT00000040334
mediator complex subunit 12
chr10_-_87067456 6.20 ENSRNOT00000014163
C-C motif chemokine receptor 7
chr1_-_175796040 6.10 ENSRNOT00000024060
murine retrovirus integration site 1 homolog
chr6_-_122239614 6.04 ENSRNOT00000005015
galactosylceramidase
chr18_-_55859333 6.02 ENSRNOT00000025989
myozenin 3
chr6_-_138772736 6.01 ENSRNOT00000071492

chr1_+_84304228 5.90 ENSRNOT00000024771
periaxin
chr8_+_67753279 5.89 ENSRNOT00000009716
calmodulin-like 4
chr1_-_127337882 5.88 ENSRNOT00000085158
aldehyde dehydrogenase 1 family, member A3
chr10_+_75087892 5.76 ENSRNOT00000065910
myeloperoxidase
chr1_-_89045586 5.75 ENSRNOT00000063808
zinc finger and BTB domain containing 32
chr12_-_16126953 5.72 ENSRNOT00000001682
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr20_+_5040337 5.71 ENSRNOT00000068435
chloride intracellular channel 1
chr2_-_186515135 5.61 ENSRNOT00000077375
kin of IRRE like (Drosophila)
chr3_-_166994286 5.60 ENSRNOT00000081593
zinc finger protein 217
chr6_-_33738825 5.57 ENSRNOT00000039492
solute carrier family 7 (cationic amino acid transporter, y+ system), member 15
chr7_+_143060597 5.57 ENSRNOT00000087481
keratin 7
chrX_+_75382598 5.54 ENSRNOT00000033494
uracil phosphoribosyltransferase homolog
chr2_+_208749996 5.54 ENSRNOT00000086321
chitinase, acidic
chr6_-_141008427 5.52 ENSRNOT00000074472

chrX_-_157331204 5.50 ENSRNOT00000085201
biglycan
chr17_-_79676499 5.45 ENSRNOT00000022711
integrin subunit alpha 8
chrX_-_138435391 5.43 ENSRNOT00000043258
muscleblind-like splicing regulator 3
chr6_+_93281408 5.41 ENSRNOT00000009610
FERM domain containing 6
chr17_-_43614844 5.32 ENSRNOT00000023054
histone cluster 1 H1 family member a
chr1_-_174495258 5.31 ENSRNOT00000052377
ENSRNOT00000086349
signal peptide, CUB domain and EGF like domain containing 2
chr4_-_165192647 5.31 ENSRNOT00000086461
killer cell lectin-like receptor, subfamily A, member 5
chr19_+_61332351 5.29 ENSRNOT00000014492
neuropilin 1
chr1_-_8751198 5.23 ENSRNOT00000030511
adhesion G protein-coupled receptor G6
chr1_-_47307488 5.23 ENSRNOT00000090033
ezrin
chr3_-_146470293 5.17 ENSRNOT00000009627
acyl-CoA synthetase short-chain family member 1
chr6_-_140418831 5.16 ENSRNOT00000086301

chr17_+_90696019 5.11 ENSRNOT00000003438
G protein-coupled receptor 137B
chr4_-_78342863 5.11 ENSRNOT00000049038
GTPase, IMAP family member 6
chr3_-_119611136 5.03 ENSRNOT00000016157
non-SMC condensin I complex, subunit H
chr17_-_9762813 4.97 ENSRNOT00000033749
solute carrier family 34 member 1
chr1_+_81230612 4.96 ENSRNOT00000026489
potassium calcium-activated channel subfamily N member 4
chr12_+_19680712 4.93 ENSRNOT00000081310

chr6_-_140266507 4.92 ENSRNOT00000082865

chr6_+_24163026 4.92 ENSRNOT00000061284
limb bud and heart development
chr3_+_112242270 4.92 ENSRNOT00000080533
ENSRNOT00000082876
calpain 3
chr1_-_169534896 4.92 ENSRNOT00000082645
tripartite motif-containing 30C
chr3_+_18787606 4.90 ENSRNOT00000090508

chr20_-_5227620 4.87 ENSRNOT00000086240
RT1 class II, locus DMb
chr11_+_60383431 4.86 ENSRNOT00000093295
Cd200 molecule
chr8_-_116045954 4.84 ENSRNOT00000020065
mitogen-activated protein kinase-activated protein kinase 3
chr8_+_118392773 4.82 ENSRNOT00000066305
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4-like
chr1_+_32221636 4.82 ENSRNOT00000022346
ENSRNOT00000089941
solute carrier family 6 member 18
chr13_+_89826254 4.81 ENSRNOT00000006141
F11 receptor
chr1_+_140601791 4.78 ENSRNOT00000091588
interferon stimulated exonuclease gene 20
chr4_-_123713319 4.78 ENSRNOT00000012875
ENSRNOT00000086982
solute carrier family 6 member 6
chr19_-_37448067 4.75 ENSRNOT00000092844
zinc finger, DHHC-type containing 1
chr19_-_55300403 4.74 ENSRNOT00000018591
ring finger protein 166
chr1_+_216293087 4.74 ENSRNOT00000027875
ENSRNOT00000087153
potassium voltage-gated channel subfamily Q member 1
chr7_+_114997103 4.73 ENSRNOT00000010224
protein tyrosine phosphatase type IVA, member 3
chr6_-_142299996 4.73 ENSRNOT00000086580
immunoglobulin heavy variable V8-2
chr5_+_118541979 4.69 ENSRNOT00000013089
EF-hand calcium binding domain 7
chr2_+_198388809 4.68 ENSRNOT00000083087
histone cluster 2, H2aa3
chr4_-_149988295 4.62 ENSRNOT00000019649
FXYD domain-containing ion transport regulator 4
chr17_-_89163113 4.61 ENSRNOT00000050445
ribosomal protein S19-like
chr10_+_56193856 4.59 ENSRNOT00000080584
ENSRNOT00000091216
ENSRNOT00000083458
tumor protein p53
chr10_+_29165577 4.57 ENSRNOT00000078415
cyclin J-like
chr10_-_4257868 4.56 ENSRNOT00000035886
TNF receptor superfamily member 17
chr13_+_50103189 4.56 ENSRNOT00000004078
ATPase plasma membrane Ca2+ transporting 4
chr13_+_88995316 4.56 ENSRNOT00000004117
olfactomedin-like 2B
chr3_-_20050486 4.55 ENSRNOT00000088887

chr12_-_6879154 4.51 ENSRNOT00000001207
arachidonate 5-lipoxygenase activating protein
chr1_-_101086198 4.45 ENSRNOT00000027917
reticulocalbin 3
chr12_-_9990284 4.43 ENSRNOT00000001264
RAS-like family 11 member A
chr16_-_47207487 4.41 ENSRNOT00000059459
dCMP deaminase
chr5_-_118541928 4.40 ENSRNOT00000012947
integrin subunit beta 3 binding protein
chr3_+_148541909 4.39 ENSRNOT00000012187
CCM2 like scaffolding protein
chr8_-_112884062 4.37 ENSRNOT00000016222
ENSRNOT00000085585
acid phosphatase, prostate
chr11_-_64853692 4.34 ENSRNOT00000002089
Cd80 molecule
chr20_+_1809078 4.34 ENSRNOT00000084853
olfactory receptor 1739
chr10_-_89088993 4.34 ENSRNOT00000027458
C-C motif chemokine receptor 10
chr6_-_30187337 4.28 ENSRNOT00000074150
intersectin 2
chr11_-_38088753 4.28 ENSRNOT00000002713
transmembrane protease, serine 2
chr5_+_104698040 4.27 ENSRNOT00000009127
ADAMTS-like 1
chr1_+_157701089 4.24 ENSRNOT00000014271
prolylcarboxypeptidase
chr8_-_132189388 4.22 ENSRNOT00000005817
zinc finger, DHHC-type containing 3
chr6_+_50528823 4.21 ENSRNOT00000008321
laminin subunit beta 1
chr10_+_17261541 4.21 ENSRNOT00000005478
SH3 and PX domains 2B
chr17_+_78879058 4.20 ENSRNOT00000022043
oleoyl-ACP hydrolase

Network of associatons between targets according to the STRING database.

First level regulatory network of Ubp1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.4 19.2 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
4.3 21.6 GO:0002317 plasma cell differentiation(GO:0002317)
4.2 16.6 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
3.9 15.8 GO:0071226 cellular response to molecule of fungal origin(GO:0071226)
3.7 22.2 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
3.7 11.0 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
3.4 3.4 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
3.3 9.9 GO:0042125 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
3.2 9.6 GO:0070946 neutrophil mediated killing of gram-positive bacterium(GO:0070946)
3.1 12.2 GO:0060857 establishment of glial blood-brain barrier(GO:0060857)
2.5 7.6 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
2.4 24.3 GO:0048251 elastic fiber assembly(GO:0048251)
2.3 9.2 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
2.2 6.5 GO:2000286 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) regulation of inward rectifier potassium channel activity(GO:1901979) positive regulation of gap junction assembly(GO:1903598) receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
2.1 6.2 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
2.0 5.9 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
2.0 7.9 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
2.0 5.9 GO:0060166 olfactory pit development(GO:0060166)
1.9 5.8 GO:0002148 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
1.9 7.6 GO:0071640 regulation of macrophage inflammatory protein 1 alpha production(GO:0071640)
1.8 7.4 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
1.8 5.4 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
1.8 5.4 GO:0002215 defense response to nematode(GO:0002215)
1.8 3.5 GO:1903849 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
1.8 5.3 GO:1904835 vestibulocochlear nerve structural organization(GO:0021649) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) renal artery morphogenesis(GO:0061441) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
1.7 5.2 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
1.7 5.2 GO:0019541 acetate metabolic process(GO:0006083) propionate metabolic process(GO:0019541)
1.7 6.8 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713) positive regulation of T-helper 17 type immune response(GO:2000318)
1.7 5.0 GO:2000118 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
1.6 4.9 GO:1990091 sodium-dependent self proteolysis(GO:1990091)
1.6 4.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.5 3.1 GO:0032752 regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
1.5 10.6 GO:0071500 cellular response to nitrosative stress(GO:0071500)
1.5 4.6 GO:0045763 regulation of arginine metabolic process(GO:0000821) negative regulation of cellular amino acid metabolic process(GO:0045763)
1.5 4.4 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
1.5 4.4 GO:0060167 regulation of adenosine receptor signaling pathway(GO:0060167)
1.4 5.7 GO:0007386 compartment pattern specification(GO:0007386)
1.4 4.2 GO:0002353 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
1.4 4.2 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
1.4 4.1 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
1.3 4.0 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
1.3 8.0 GO:0031133 cellular magnesium ion homeostasis(GO:0010961) regulation of axon diameter(GO:0031133)
1.3 6.3 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
1.3 3.8 GO:0042891 antibiotic transport(GO:0042891)
1.2 9.9 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
1.2 4.9 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
1.2 6.0 GO:0006681 galactosylceramide metabolic process(GO:0006681)
1.2 3.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
1.1 4.6 GO:1904024 negative regulation of fermentation(GO:1901003) negative regulation of NAD metabolic process(GO:1902689) negative regulation of glucose catabolic process to lactate via pyruvate(GO:1904024)
1.1 4.5 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
1.1 6.7 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
1.1 5.5 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
1.1 4.4 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.1 23.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
1.1 5.3 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
1.1 3.2 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
1.0 5.0 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.9 2.8 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.9 5.4 GO:0003383 apical constriction(GO:0003383)
0.9 2.6 GO:0006649 phospholipid transfer to membrane(GO:0006649)
0.8 4.2 GO:1904179 positive regulation of adipose tissue development(GO:1904179)
0.8 11.7 GO:0002827 positive regulation of T-helper 1 type immune response(GO:0002827)
0.8 3.3 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.8 4.9 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.8 11.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.8 9.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.8 5.5 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.8 4.7 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.8 11.0 GO:0045059 positive thymic T cell selection(GO:0045059)
0.8 2.3 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.7 7.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.7 2.2 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.7 2.9 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.7 7.2 GO:0019695 choline metabolic process(GO:0019695)
0.7 9.9 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.7 8.4 GO:0046541 saliva secretion(GO:0046541)
0.7 5.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.6 10.8 GO:0031295 T cell costimulation(GO:0031295)
0.6 2.5 GO:0031179 peptide modification(GO:0031179)
0.6 2.5 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.6 3.8 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.6 7.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.6 6.1 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.6 4.8 GO:0044351 macropinocytosis(GO:0044351)
0.6 3.0 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.6 4.2 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.6 6.6 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.6 1.8 GO:0040009 regulation of growth rate(GO:0040009)
0.6 2.3 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.6 7.4 GO:0002024 diet induced thermogenesis(GO:0002024)
0.5 4.9 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.5 2.6 GO:1901656 glycoside transport(GO:1901656)
0.5 1.5 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.5 3.6 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.5 2.0 GO:0009597 detection of virus(GO:0009597)
0.5 5.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.5 1.5 GO:0032218 riboflavin transport(GO:0032218)
0.5 2.9 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.5 1.0 GO:0001807 regulation of type IV hypersensitivity(GO:0001807)
0.5 3.9 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.5 2.4 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.5 3.9 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.5 4.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.5 1.4 GO:0002333 transitional stage B cell differentiation(GO:0002332) transitional one stage B cell differentiation(GO:0002333) positive regulation of actin filament binding(GO:1904531) positive regulation of actin binding(GO:1904618)
0.5 1.9 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) protein K29-linked ubiquitination(GO:0035519)
0.5 7.0 GO:0034389 lipid particle organization(GO:0034389)
0.5 2.3 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.5 6.9 GO:0015671 oxygen transport(GO:0015671)
0.5 1.4 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.4 3.5 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.4 3.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.4 1.7 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.4 7.2 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.4 0.4 GO:0043132 NAD transport(GO:0043132)
0.4 5.8 GO:0060347 heart trabecula formation(GO:0060347)
0.4 6.9 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.4 1.2 GO:0018343 protein farnesylation(GO:0018343)
0.4 2.4 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.4 2.0 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.4 9.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.4 3.5 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.4 1.9 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.4 5.7 GO:0043486 histone exchange(GO:0043486)
0.4 4.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.4 1.8 GO:1904717 regulation of AMPA glutamate receptor clustering(GO:1904717)
0.4 2.6 GO:0043615 astrocyte cell migration(GO:0043615)
0.4 2.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.4 1.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.4 3.2 GO:0099638 endosome to plasma membrane protein transport(GO:0099638)
0.4 2.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.3 9.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.3 1.3 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.3 1.0 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.3 1.6 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.3 1.0 GO:0046380 N-acetylglucosamine biosynthetic process(GO:0006045) N-acetylneuraminate biosynthetic process(GO:0046380)
0.3 2.2 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.3 1.9 GO:0015074 DNA integration(GO:0015074)
0.3 1.5 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.3 1.8 GO:0034059 response to anoxia(GO:0034059)
0.3 1.5 GO:0010819 regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820)
0.3 1.2 GO:0010446 response to alkaline pH(GO:0010446)
0.3 11.6 GO:0050798 activated T cell proliferation(GO:0050798)
0.3 1.9 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.3 6.6 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.3 0.8 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.3 2.2 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.3 9.0 GO:0018345 protein palmitoylation(GO:0018345)
0.3 2.4 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.3 1.8 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.3 6.4 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.3 3.8 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
0.3 1.0 GO:0060468 prevention of polyspermy(GO:0060468)
0.2 1.0 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.2 0.7 GO:0032910 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916)
0.2 1.9 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 2.7 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.2 1.3 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.2 2.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 2.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 3.3 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.2 0.8 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.2 1.4 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2 3.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.2 4.4 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.2 0.6 GO:1901367 response to L-cysteine(GO:1901367)
0.2 9.3 GO:0035904 aorta development(GO:0035904)
0.2 5.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 0.2 GO:0036334 epidermal stem cell homeostasis(GO:0036334)
0.2 2.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 1.1 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.2 1.4 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.2 1.6 GO:2000210 positive regulation of anoikis(GO:2000210)
0.2 1.0 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.2 2.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 7.6 GO:0035987 endodermal cell differentiation(GO:0035987)
0.2 2.9 GO:0048266 behavioral response to pain(GO:0048266)
0.2 1.3 GO:0001927 exocyst assembly(GO:0001927)
0.2 4.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 2.9 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.2 2.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 0.6 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 6.5 GO:0015804 neutral amino acid transport(GO:0015804)
0.2 6.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 2.2 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 0.4 GO:0071221 response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.1 0.3 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.1 2.4 GO:0006152 purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.1 3.2 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 1.0 GO:0060346 bone trabecula formation(GO:0060346)
0.1 2.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 5.1 GO:0030101 natural killer cell activation(GO:0030101)
0.1 1.5 GO:0002507 tolerance induction(GO:0002507)
0.1 3.1 GO:0048240 sperm capacitation(GO:0048240)
0.1 0.2 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 3.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 2.9 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 1.9 GO:0019236 response to pheromone(GO:0019236)
0.1 3.6 GO:0006220 pyrimidine nucleotide metabolic process(GO:0006220)
0.1 3.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.5 GO:0071926 endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 1.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 1.3 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.9 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 0.4 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.1 3.2 GO:0006972 hyperosmotic response(GO:0006972)
0.1 1.1 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1 0.6 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.1 1.2 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.1 0.6 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 1.7 GO:0060037 pharyngeal system development(GO:0060037)
0.1 1.6 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1 10.5 GO:0045727 positive regulation of translation(GO:0045727)
0.1 2.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.3 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.1 3.0 GO:0030199 collagen fibril organization(GO:0030199)
0.1 4.6 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.1 0.6 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.1 4.3 GO:0007004 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.1 4.1 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 0.7 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.8 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.1 1.0 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 3.3 GO:1901998 toxin transport(GO:1901998)
0.1 1.9 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 2.1 GO:0015701 bicarbonate transport(GO:0015701)
0.1 5.8 GO:0042098 T cell proliferation(GO:0042098)
0.1 0.5 GO:0071680 response to indole-3-methanol(GO:0071680)
0.1 2.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.8 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 3.5 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 1.3 GO:0001556 oocyte maturation(GO:0001556)
0.1 3.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 3.1 GO:0006284 base-excision repair(GO:0006284)
0.1 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 7.5 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.1 0.3 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 0.8 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 3.3 GO:0033045 regulation of sister chromatid segregation(GO:0033045)
0.1 2.6 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 1.0 GO:0001675 acrosome assembly(GO:0001675)
0.1 2.1 GO:0060074 synapse maturation(GO:0060074)
0.1 0.9 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 7.7 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 2.0 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 1.1 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.6 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.4 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.5 GO:0060028 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) convergent extension involved in axis elongation(GO:0060028) convergent extension involved in organogenesis(GO:0060029)
0.1 2.7 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.1 2.0 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 5.0 GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process(GO:1903052)
0.1 1.1 GO:0014002 astrocyte development(GO:0014002)
0.1 3.9 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.1 1.4 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 0.7 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.1 1.6 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.0 2.0 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 1.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.3 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 2.8 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 2.0 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 1.2 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 4.2 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 2.8 GO:0006342 chromatin silencing(GO:0006342)
0.0 3.3 GO:0007127 meiosis I(GO:0007127)
0.0 1.9 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 1.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 2.8 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0007398 ectoderm development(GO:0007398)
0.0 0.3 GO:0090169 regulation of spindle assembly(GO:0090169) regulation of mitotic spindle assembly(GO:1901673)
0.0 2.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:0006308 DNA catabolic process(GO:0006308)
0.0 1.2 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.9 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.7 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.4 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.5 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 1.7 GO:0042110 T cell activation(GO:0042110) T cell aggregation(GO:0070489)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 24.3 GO:0071953 elastic fiber(GO:0071953)
3.2 9.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
1.4 16.6 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
1.4 11.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
1.3 5.2 GO:0036398 TCR signalosome(GO:0036398) microspike(GO:0044393)
1.2 8.6 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
1.1 4.2 GO:0005607 laminin-1 complex(GO:0005606) laminin-2 complex(GO:0005607) laminin-10 complex(GO:0043259)
1.0 9.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.9 11.5 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.8 19.7 GO:0001891 phagocytic cup(GO:0001891)
0.7 6.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.7 2.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.7 7.5 GO:0031010 ISWI-type complex(GO:0031010)
0.6 5.1 GO:0097443 sorting endosome(GO:0097443)
0.6 5.0 GO:0000796 condensin complex(GO:0000796)
0.6 6.9 GO:0005833 hemoglobin complex(GO:0005833)
0.6 7.4 GO:0005859 muscle myosin complex(GO:0005859)
0.6 2.9 GO:0043293 apoptosome(GO:0043293)
0.5 20.7 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.5 3.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.5 1.5 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.5 3.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.5 2.0 GO:0097427 microtubule bundle(GO:0097427)
0.5 4.8 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.5 2.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.4 3.1 GO:0036128 CatSper complex(GO:0036128)
0.4 36.5 GO:0031526 brush border membrane(GO:0031526)
0.4 3.6 GO:0032437 cuticular plate(GO:0032437)
0.3 5.8 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.3 7.4 GO:0031091 platelet alpha granule(GO:0031091)
0.3 1.2 GO:0044299 C-fiber(GO:0044299)
0.3 3.3 GO:0005915 zonula adherens(GO:0005915)
0.3 4.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 2.4 GO:0032584 growth cone membrane(GO:0032584)
0.3 1.1 GO:0071203 WASH complex(GO:0071203)
0.3 4.7 GO:0042589 zymogen granule membrane(GO:0042589)
0.3 7.2 GO:0042629 mast cell granule(GO:0042629)
0.3 2.2 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.3 0.8 GO:0044609 DBIRD complex(GO:0044609)
0.3 1.3 GO:1990130 Iml1 complex(GO:1990130)
0.2 0.7 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.2 17.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 1.6 GO:0033010 paranodal junction(GO:0033010)
0.2 4.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 2.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 34.1 GO:0001650 fibrillar center(GO:0001650)
0.2 2.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 1.7 GO:0031931 TORC1 complex(GO:0031931)
0.2 0.4 GO:0032807 DNA ligase IV complex(GO:0032807)
0.2 5.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.2 2.5 GO:0000812 Swr1 complex(GO:0000812)
0.2 15.2 GO:0005581 collagen trimer(GO:0005581)
0.2 1.4 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.2 1.4 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.2 17.5 GO:0031985 Golgi cisterna(GO:0031985)
0.2 15.5 GO:0005604 basement membrane(GO:0005604)
0.2 0.9 GO:0035061 interchromatin granule(GO:0035061)
0.2 10.6 GO:0005876 spindle microtubule(GO:0005876)
0.2 2.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 1.4 GO:0031209 SCAR complex(GO:0031209)
0.2 6.8 GO:0002102 podosome(GO:0002102)
0.2 7.2 GO:0016592 mediator complex(GO:0016592)
0.2 3.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 2.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.4 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 3.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 5.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.1 GO:0097452 CRD-mediated mRNA stability complex(GO:0070937) GAIT complex(GO:0097452)
0.1 4.6 GO:0005669 transcription factor TFIID complex(GO:0005669) site of double-strand break(GO:0035861)
0.1 11.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 1.3 GO:0043034 costamere(GO:0043034)
0.1 1.1 GO:0005796 Golgi lumen(GO:0005796)
0.1 3.9 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.5 GO:0032426 stereocilium tip(GO:0032426)
0.1 7.7 GO:0045178 basal part of cell(GO:0045178)
0.1 0.5 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 29.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 3.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 4.8 GO:0015030 Cajal body(GO:0015030)
0.1 1.1 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 5.7 GO:0034707 chloride channel complex(GO:0034707)
0.1 7.0 GO:0005811 lipid particle(GO:0005811)
0.1 1.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 5.6 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 4.4 GO:0016235 aggresome(GO:0016235)
0.1 14.1 GO:0001726 ruffle(GO:0001726)
0.1 2.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 1.4 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 5.6 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 5.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 2.9 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.3 GO:0000145 exocyst(GO:0000145)
0.1 2.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 3.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 5.2 GO:0030018 Z disc(GO:0030018)
0.1 7.6 GO:0042383 sarcolemma(GO:0042383)
0.1 0.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 5.8 GO:0098802 plasma membrane receptor complex(GO:0098802)
0.1 1.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 2.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.2 GO:0030686 90S preribosome(GO:0030686)
0.0 4.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 2.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 9.6 GO:0005840 ribosome(GO:0005840)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 1.7 GO:0005657 replication fork(GO:0005657)
0.0 1.7 GO:0045095 keratin filament(GO:0045095)
0.0 1.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 9.5 GO:0000228 nuclear chromosome(GO:0000228)
0.0 0.9 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)
0.0 3.4 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 6.5 GO:0005813 centrosome(GO:0005813)
0.0 9.4 GO:0005730 nucleolus(GO:0005730)
0.0 2.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.5 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 22.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
3.8 22.8 GO:0048030 disaccharide binding(GO:0048030)
2.9 11.7 GO:0005143 interleukin-12 receptor binding(GO:0005143)
2.5 9.9 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
2.2 6.7 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
2.0 25.5 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
1.9 7.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
1.8 11.0 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.6 4.8 GO:0030977 taurine binding(GO:0030977)
1.5 7.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.4 13.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.4 4.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
1.3 5.3 GO:0097108 hedgehog family protein binding(GO:0097108)
1.3 5.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
1.3 19.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
1.3 3.8 GO:0042895 antibiotic transporter activity(GO:0042895)
1.2 31.0 GO:0042288 MHC class I protein binding(GO:0042288)
1.2 9.7 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
1.2 4.7 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
1.1 5.5 GO:0004849 uridine kinase activity(GO:0004849)
1.0 22.0 GO:0023026 MHC class II protein complex binding(GO:0023026)
1.0 5.0 GO:0044547 DNA topoisomerase binding(GO:0044547)
1.0 5.0 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
1.0 2.9 GO:0016882 cyclo-ligase activity(GO:0016882)
1.0 4.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.9 5.5 GO:0004568 chitinase activity(GO:0004568)
0.9 3.5 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.8 6.4 GO:0045545 syndecan binding(GO:0045545)
0.8 3.1 GO:0019863 IgE binding(GO:0019863)
0.8 3.9 GO:0042731 PH domain binding(GO:0042731)
0.8 3.8 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
0.7 7.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.7 5.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.7 7.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.7 5.3 GO:0038085 vascular endothelial growth factor-activated receptor activity(GO:0005021) vascular endothelial growth factor binding(GO:0038085)
0.7 5.9 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.6 3.9 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.6 1.9 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.6 3.7 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.6 7.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.6 4.8 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.6 3.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.6 7.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.6 3.9 GO:0003896 DNA primase activity(GO:0003896)
0.6 3.9 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.5 2.6 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.5 2.6 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.5 2.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.5 4.6 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.5 3.5 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.5 1.5 GO:0032217 riboflavin transporter activity(GO:0032217)
0.5 2.0 GO:0042610 CD8 receptor binding(GO:0042610)
0.5 6.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.5 3.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.5 4.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.5 6.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.4 4.9 GO:0031432 titin binding(GO:0031432)
0.4 4.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.4 4.4 GO:0033265 choline binding(GO:0033265)
0.4 2.5 GO:0003840 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.4 2.1 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.4 2.4 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.4 4.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.4 2.7 GO:0016936 galactoside binding(GO:0016936)
0.4 1.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.4 5.1 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.4 1.1 GO:0000827 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827)
0.4 7.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.4 2.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 5.2 GO:0044548 S100 protein binding(GO:0044548)
0.3 8.0 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.3 3.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 16.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.3 7.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3 16.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3 0.6 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.3 2.8 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.3 3.0 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.3 3.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.3 4.1 GO:0045499 chemorepellent activity(GO:0045499)
0.3 3.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 2.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.3 1.7 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.3 2.6 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.3 11.2 GO:0004601 peroxidase activity(GO:0004601)
0.3 1.4 GO:0031404 chloride ion binding(GO:0031404)
0.3 4.2 GO:0004312 fatty acid synthase activity(GO:0004312)
0.3 21.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.3 2.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.3 2.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.3 14.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 1.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.3 0.8 GO:0016509 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.3 3.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.3 2.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.3 1.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.3 1.5 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.2 0.7 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.2 1.0 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 3.2 GO:0042301 phosphate ion binding(GO:0042301)
0.2 3.4 GO:0015250 water channel activity(GO:0015250)
0.2 0.7 GO:1990763 arrestin family protein binding(GO:1990763)
0.2 20.5 GO:0005178 integrin binding(GO:0005178)
0.2 3.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 7.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 2.9 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 1.5 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.2 3.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 8.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 16.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2 0.8 GO:0032190 acrosin binding(GO:0032190)
0.2 1.2 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.2 1.2 GO:0017040 ceramidase activity(GO:0017040)
0.2 0.8 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 0.8 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.2 0.6 GO:0003921 GMP synthase activity(GO:0003921) GMP synthase (glutamine-hydrolyzing) activity(GO:0003922)
0.2 2.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 1.5 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 4.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 4.4 GO:0019239 deaminase activity(GO:0019239)
0.2 1.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2 4.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.2 2.4 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.2 1.9 GO:0008097 5S rRNA binding(GO:0008097)
0.2 0.6 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.2 1.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 3.8 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 2.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 3.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 3.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 2.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 4.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 7.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 2.5 GO:0042169 SH2 domain binding(GO:0042169)
0.1 6.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.9 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 5.7 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.1 2.7 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.1 1.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 4.7 GO:0019843 rRNA binding(GO:0019843)
0.1 0.8 GO:0004445 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1 1.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 2.2 GO:0031489 myosin V binding(GO:0031489)
0.1 1.6 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.1 1.1 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.4 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 12.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 0.4 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.2 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.1 2.0 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 3.7 GO:0017022 myosin binding(GO:0017022)
0.1 2.8 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 2.1 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.1 8.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 7.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 3.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 5.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 2.7 GO:0015485 cholesterol binding(GO:0015485)
0.1 1.9 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.1 6.9 GO:0030165 PDZ domain binding(GO:0030165)
0.1 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 1.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 2.3 GO:0051119 sugar transmembrane transporter activity(GO:0051119)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.6 GO:0019213 deacetylase activity(GO:0019213)
0.0 1.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 1.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.0 6.0 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 2.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 7.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 2.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 2.9 GO:0070035 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 2.4 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 4.7 GO:0003712 transcription cofactor activity(GO:0003712)
0.0 0.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 9.6 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 1.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.9 GO:0004519 endonuclease activity(GO:0004519)
0.0 3.6 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 1.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.3 GO:0019902 phosphatase binding(GO:0019902)
0.0 4.7 GO:0051020 GTPase binding(GO:0051020)
0.0 10.5 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.2 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 1.5 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 17.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.5 17.5 PID IL23 PATHWAY IL23-mediated signaling events
0.5 9.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.5 5.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.5 7.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.5 17.9 PID RAS PATHWAY Regulation of Ras family activation
0.5 15.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.4 6.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.4 14.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.4 8.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 4.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.3 16.4 NABA COLLAGENS Genes encoding collagen proteins
0.3 11.0 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.3 9.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.3 15.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.3 4.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 5.6 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.2 3.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.2 32.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 5.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.2 6.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.2 0.7 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.2 2.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 1.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.2 5.1 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 3.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 3.2 PID EPO PATHWAY EPO signaling pathway
0.1 4.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 5.8 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 3.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 4.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 6.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 5.0 PID AURORA B PATHWAY Aurora B signaling
0.1 3.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 4.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 1.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 1.8 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 2.1 PID RHOA PATHWAY RhoA signaling pathway
0.1 2.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 2.8 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 1.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 2.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 0.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 2.4 PID PLK1 PATHWAY PLK1 signaling events
0.1 0.6 PID IL3 PATHWAY IL3-mediated signaling events
0.1 9.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.0 PID ATM PATHWAY ATM pathway
0.1 3.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.2 PID MYC PATHWAY C-MYC pathway
0.0 1.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 2.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.6 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 19.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
1.4 11.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.2 14.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
1.0 9.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.6 5.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.6 5.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.6 28.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.5 5.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.5 6.8 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.4 5.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.4 6.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.4 2.8 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.4 28.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.3 2.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.3 6.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.3 19.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.3 4.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 12.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 28.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.3 4.4 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.3 10.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.3 5.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.3 3.8 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.3 3.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 3.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.3 6.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.3 6.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 6.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 1.4 REACTOME DEFENSINS Genes involved in Defensins
0.2 4.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 2.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 2.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 4.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 3.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 11.5 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.2 5.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 5.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.2 7.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 4.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.2 2.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 6.5 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.2 0.5 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.2 2.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 2.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 3.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 2.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 3.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.1 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 2.1 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 5.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 4.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 2.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 0.4 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 2.3 REACTOME KINESINS Genes involved in Kinesins
0.1 1.8 REACTOME INTERFERON SIGNALING Genes involved in Interferon Signaling
0.1 6.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 2.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 0.7 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 1.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 0.4 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.1 1.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 0.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.3 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 1.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.9 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 1.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.8 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation