Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Trp73

Z-value: 0.53

Motif logo

logo of

Transcription factors associated with Trp73

Gene Symbol Gene ID Gene Info

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tp73rn6_v1_chr5_-_171415354_1714153540.036.2e-01Click!

Activity profile of Trp73 motif

Sorted Z-values of Trp73 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_162385575 20.86 ENSRNOT00000016540
Thrsp
thyroid hormone responsive
chr8_-_62948720 14.28 ENSRNOT00000075476
Islr
immunoglobulin superfamily containing leucine-rich repeat
chr14_+_7618022 10.23 ENSRNOT00000088508
ENSRNOT00000002819
Slc10a6
solute carrier family 10 member 6
chr16_-_69132584 10.11 ENSRNOT00000017776
Adgra2
adhesion G protein-coupled receptor A2
chr13_+_100980574 9.70 ENSRNOT00000067005
ENSRNOT00000004649
Capn8
calpain 8
chr2_-_88314254 9.13 ENSRNOT00000038546
Car13
carbonic anhydrase 13
chr11_-_73678984 8.93 ENSRNOT00000002355
Fam43a
family with sequence similarity 43, member A
chr3_+_110734105 8.64 ENSRNOT00000073587
Chst14
carbohydrate sulfotransferase 14
chr9_-_61690956 8.12 ENSRNOT00000066589
Hspd1
heat shock protein family D member 1
chr10_+_88326337 7.52 ENSRNOT00000022029
ENSRNOT00000076461
Fkbp10
FK506 binding protein 10
chr10_+_88326080 7.15 ENSRNOT00000076475
Fkbp10
FK506 binding protein 10
chr11_-_81334120 6.69 ENSRNOT00000089988
Adipoq
adiponectin, C1Q and collagen domain containing
chr3_+_45683993 6.56 ENSRNOT00000038983
Tanc1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr5_+_119903507 6.37 ENSRNOT00000033933
Raver2
ribonucleoprotein, PTB-binding 2
chr3_+_110723481 5.88 ENSRNOT00000013878
Bahd1
bromo adjacent homology domain containing 1
chr15_+_120372 5.66 ENSRNOT00000007828
Dlg5
discs large MAGUK scaffold protein 5
chr10_+_103395511 5.66 ENSRNOT00000004256
Gprc5c
G protein-coupled receptor, class C, group 5, member C
chr1_-_213987053 5.36 ENSRNOT00000072774
LOC100911519
p53-induced protein with a death domain-like
chr8_-_115388266 4.72 ENSRNOT00000018122
Tex264
testis expressed 264
chr10_+_15241590 4.04 ENSRNOT00000037372
ENSRNOT00000037381
Mettl26
methyltransferase like 26
chr20_+_5933595 3.62 ENSRNOT00000000618
Mapk14
mitogen activated protein kinase 14
chr5_-_166924136 3.19 ENSRNOT00000085251
Spsb1
splA/ryanodine receptor domain and SOCS box containing 1
chr18_-_24823837 3.15 ENSRNOT00000021405
ENSRNOT00000090390
Myo7b
myosin VIIb
chr7_-_47928674 2.76 ENSRNOT00000038144
Mettl25
methyltransferase like 25
chr10_-_15590220 2.62 ENSRNOT00000048977
Hba-a2
hemoglobin alpha, adult chain 2
chr9_+_16647922 2.60 ENSRNOT00000031625
Klc4
kinesin light chain 4
chr8_+_117455262 2.60 ENSRNOT00000027520
Slc25a20
solute carrier family 25 member 20
chr15_+_34552410 2.52 ENSRNOT00000027802
Khnyn
KH and NYN domain containing
chr3_+_11921715 2.43 ENSRNOT00000021689
Fam129b
family with sequence similarity 129, member B
chrX_-_13116743 2.34 ENSRNOT00000004305
Mid1ip1
MID1 interacting protein 1
chr1_+_48008683 2.34 ENSRNOT00000018934
Acat2l1
acetyl-CoA acetyltransferase 2-like 1
chr11_+_60383431 2.17 ENSRNOT00000093295
Cd200
Cd200 molecule
chr9_-_16647458 2.10 ENSRNOT00000024380
Mrpl2
mitochondrial ribosomal protein L2
chr20_-_5455632 1.97 ENSRNOT00000000552
Wdr46
WD repeat domain 46
chr1_-_87777668 1.97 ENSRNOT00000037288
AABR07002870.1

chr2_-_250981623 1.93 ENSRNOT00000018435
Clca2
chloride channel accessory 2
chr8_+_106503504 1.84 ENSRNOT00000018755
Rbp2
retinol binding protein 2
chr10_+_52334240 1.76 ENSRNOT00000005518
Zfp18
zinc finger protein 18
chr1_+_77541359 1.73 ENSRNOT00000049028
LOC103690015
40S ribosomal protein S19-like
chr5_+_59008933 1.67 ENSRNOT00000023060
Car9
carbonic anhydrase 9
chr3_-_153114520 1.66 ENSRNOT00000008254
Dsn1
DSN1 homolog, MIS12 kinetochore complex component
chr5_+_59080765 1.63 ENSRNOT00000021888
ENSRNOT00000064419
Rgp1
RGP1 homolog, RAB6A GEF complex partner 1
chr9_+_16647598 1.56 ENSRNOT00000087413
Klc4
kinesin light chain 4
chr12_+_47218969 1.19 ENSRNOT00000081343
ENSRNOT00000038395
Unc119b
unc-119 lipid binding chaperone B
chr4_-_129846642 1.17 ENSRNOT00000010717
Frmd4b
FERM domain containing 4B
chr5_-_153924896 1.14 ENSRNOT00000065247
Grhl3
grainyhead-like transcription factor 3
chr18_+_57011575 1.14 ENSRNOT00000026679
Il17b
interleukin 17B
chr10_-_78219793 1.12 ENSRNOT00000003369
Tom1l1
target of myb1 like 1 membrane trafficking protein
chr10_+_85978691 1.02 ENSRNOT00000006359
Rpl19
ribosomal protein L19
chr10_+_55478298 0.84 ENSRNOT00000038454
Rnf222
ring finger protein 222
chr3_-_72113680 0.78 ENSRNOT00000009708
Zdhhc5
zinc finger, DHHC-type containing 5
chr20_-_43108198 0.74 ENSRNOT00000000742
Hdac2
histone deacetylase 2
chr1_-_167588630 0.23 ENSRNOT00000050707
Olr39
olfactory receptor 39
chr6_-_132797675 0.11 ENSRNOT00000006128
Wars
tryptophanyl-tRNA synthetase
chr7_+_47928060 0.04 ENSRNOT00000005740
Ccdc59
coiled-coil domain containing 59

Network of associatons between targets according to the STRING database.

First level regulatory network of Trp73

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.1 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
2.7 8.1 GO:0045041 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) protein import into mitochondrial intermembrane space(GO:0045041)
1.7 6.7 GO:0072312 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532)
1.4 5.7 GO:0071896 protein localization to adherens junction(GO:0071896)
1.1 8.6 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.9 3.6 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.8 20.9 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.6 2.6 GO:0015879 carnitine transport(GO:0015879)
0.6 3.2 GO:1904970 brush border assembly(GO:1904970)
0.4 5.9 GO:0031507 heterochromatin assembly(GO:0031507)
0.3 14.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.3 10.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.3 2.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.3 1.8 GO:0006776 vitamin A metabolic process(GO:0006776)
0.3 6.6 GO:0097062 dendritic spine maintenance(GO:0097062)
0.2 0.7 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.2 2.6 GO:0015671 oxygen transport(GO:0015671)
0.1 2.3 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 2.4 GO:0032274 gonadotropin secretion(GO:0032274)
0.1 1.1 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.1 1.1 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 0.8 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 9.7 GO:0007586 digestion(GO:0007586)
0.1 1.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 2.1 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 10.2 GO:0006814 sodium ion transport(GO:0006814)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.7 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 6.4 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 2.0 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.6 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 1.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.0 GO:0097421 liver regeneration(GO:0097421)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 8.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.7 2.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.7 5.9 GO:0005677 chromatin silencing complex(GO:0005677)
0.4 1.7 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.7 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 6.7 GO:0005581 collagen trimer(GO:0005581)
0.1 7.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 4.2 GO:0005871 kinesin complex(GO:0005871)
0.0 3.2 GO:0016459 myosin complex(GO:0016459)
0.0 9.1 GO:0043209 myelin sheath(GO:0043209)
0.0 2.1 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 6.6 GO:0043679 axon terminus(GO:0043679)
0.0 3.6 GO:0000922 spindle pole(GO:0000922)
0.0 1.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.8 GO:0000152 nuclear ubiquitin ligase complex(GO:0000152)
0.0 5.7 GO:0043235 receptor complex(GO:0043235)
0.0 15.5 GO:0005615 extracellular space(GO:0005615)
0.0 10.1 GO:0009986 cell surface(GO:0009986)
0.0 13.3 GO:0005794 Golgi apparatus(GO:0005794)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 8.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
1.4 8.6 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
1.1 14.7 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.9 2.6 GO:0031720 haptoglobin binding(GO:0031720)
0.9 2.6 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.8 10.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.5 6.7 GO:0033691 sialic acid binding(GO:0033691)
0.5 3.6 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273) NFAT protein binding(GO:0051525)
0.4 9.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 0.7 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.2 1.0 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 1.8 GO:0019841 retinol binding(GO:0019841)
0.1 1.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 10.2 GO:0015293 symporter activity(GO:0015293)
0.1 5.7 GO:0008013 beta-catenin binding(GO:0008013)
0.1 7.3 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 1.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.1 GO:0030276 clathrin binding(GO:0030276)
0.0 16.9 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 3.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 2.4 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 2.3 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 2.3 GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups(GO:0016747)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 3.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 6.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 10.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 3.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.2 8.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.2 8.6 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1 4.2 REACTOME KINESINS Genes involved in Kinesins
0.1 2.6 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 6.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation