Project
GSE53960: rat RNA-Seq transcriptomic Bodymap
Navigation
Downloads
Results for Trp63
Z-value: 0.35
Motif logo
Transcription factors associated with Trp63
| Gene Symbol | Gene ID | Gene Info |
|---|
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Tp63 | rn6_v1_chr11_-_78341349_78341349 | 0.22 | 5.6e-05 | Click! |
Top targets:  
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr17_-_80807181 Show fit | 17.65 |
ENSRNOT00000040052
ENSRNOT00000090064 |
cubilin |
|
| chr10_-_56465393 Show fit | 8.96 |
ENSRNOT00000056860
|
tyrosine kinase, non-receptor, 1 |
|
| chr16_-_69132584 Show fit | 7.64 |
ENSRNOT00000017776
|
adhesion G protein-coupled receptor A2 |
|
| chr16_-_50501716 Show fit | 7.02 |
ENSRNOT00000067486
|
FAT atypical cadherin 1 |
|
| chr12_-_23661009 Show fit | 6.98 |
ENSRNOT00000059451
|
uroplakin 3B-like |
|
| chr16_-_50501921 Show fit | 6.76 |
ENSRNOT00000081023
|
FAT atypical cadherin 1 |
|
| chr17_-_90627101 Show fit | 5.82 |
ENSRNOT00000003349
|
nidogen 1 |
|
| chr2_-_219097619 Show fit | 5.13 |
ENSRNOT00000078806
|
vascular cell adhesion molecule 1 |
|
| chr6_-_77848434 Show fit | 4.63 |
ENSRNOT00000034342
|
solute carrier family 25 member 21 |
|
| chr1_-_59347472 Show fit | 4.21 |
ENSRNOT00000017718
|
leucyl and cystinyl aminopeptidase |
Network of associatons between targets according to the STRING database.
First level regulatory network of Trp63
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.5 | 17.6 | GO:0015889 | cobalamin transport(GO:0015889) |
| 0.3 | 13.8 | GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197) |
| 0.1 | 9.0 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) |
| 2.5 | 7.6 | GO:0090210 | regulation of establishment of blood-brain barrier(GO:0090210) |
| 0.1 | 6.9 | GO:0032092 | positive regulation of protein binding(GO:0032092) |
| 0.4 | 5.8 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.5 | 5.1 | GO:0022614 | membrane to membrane docking(GO:0022614) |
| 1.4 | 4.2 | GO:0010813 | neuropeptide catabolic process(GO:0010813) |
| 0.2 | 3.8 | GO:0038166 | angiotensin-activated signaling pathway(GO:0038166) |
| 0.5 | 3.4 | GO:0099525 | positive regulation of synaptic vesicle priming(GO:0010808) presynaptic dense core granule exocytosis(GO:0099525) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 17.6 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.1 | 13.8 | GO:0030175 | filopodium(GO:0030175) |
| 0.1 | 9.0 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 1.2 | 6.9 | GO:0030478 | actin cap(GO:0030478) |
| 0.2 | 5.8 | GO:0005605 | basal lamina(GO:0005605) |
| 1.3 | 5.1 | GO:0071065 | alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065) |
| 0.0 | 4.6 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.3 | 4.2 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.4 | 3.4 | GO:0044305 | calyx of Held(GO:0044305) |
| 0.0 | 3.1 | GO:0005769 | early endosome(GO:0005769) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.5 | 17.6 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 0.0 | 13.8 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.1 | 9.0 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.1 | 6.9 | GO:0017022 | myosin binding(GO:0017022) |
| 0.7 | 5.8 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.5 | 5.1 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.6 | 4.2 | GO:0001595 | angiotensin receptor activity(GO:0001595) |
| 0.2 | 3.8 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.4 | 3.4 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.0 | 3.1 | GO:0016874 | ligase activity(GO:0016874) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.8 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.3 | 5.1 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.1 | 4.2 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.1 | 4.2 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.2 | 2.4 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 17.6 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.3 | 6.9 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 5.1 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 4.6 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 1.4 | 4.2 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.1 | 3.4 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.1 | 2.8 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.1 | 2.4 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.0 | 1.3 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |