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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Tgif2_Tgif2lx1_Tgif2lx2

Z-value: 0.94

Motif logo

Transcription factors associated with Tgif2_Tgif2lx1_Tgif2lx2

Gene Symbol Gene ID Gene Info
ENSRNOG00000042374 TGFB-induced factor homeobox 2
ENSRNOG00000029850 TGFB-induced factor homeobox 2-like, X-linked 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tgif2lx2rn6_v1_chrX_+_90588124_905881240.172.7e-03Click!
Tgif2rn6_v1_chr3_+_152909189_152909189-0.122.7e-02Click!

Activity profile of Tgif2_Tgif2lx1_Tgif2lx2 motif

Sorted Z-values of Tgif2_Tgif2lx1_Tgif2lx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_72219246 69.98 ENSRNOT00000009903
smoothelin-like 1
chr4_+_144382945 35.62 ENSRNOT00000007601
caveolin 3
chr1_+_80321585 35.34 ENSRNOT00000022895
creatine kinase, M-type
chr7_-_29152442 33.21 ENSRNOT00000079774
myosin binding protein C, slow type
chr5_+_154522119 31.71 ENSRNOT00000072618
E2F transcription factor 2
chr9_-_43116521 25.51 ENSRNOT00000039437
ankyrin repeat domain 23
chr13_+_52889737 23.00 ENSRNOT00000074366
calcium voltage-gated channel subunit alpha1 S
chr3_-_121822436 21.67 ENSRNOT00000039794
cytoskeleton associated protein 2-like
chr10_+_59529785 20.29 ENSRNOT00000064840
ENSRNOT00000065181
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr16_+_75572070 15.96 ENSRNOT00000043486
defensin beta 52
chr2_-_88135410 15.93 ENSRNOT00000014180
carbonic anhydrase 3
chr3_-_16753987 14.96 ENSRNOT00000091257

chr10_-_74413745 13.82 ENSRNOT00000038296
proline rich 11
chrX_-_138435391 13.56 ENSRNOT00000043258
muscleblind-like splicing regulator 3
chrX_+_136460215 12.76 ENSRNOT00000093538
Rho GTPase activating protein 36
chr1_-_145870912 12.36 ENSRNOT00000016289
interleukin 16
chr5_+_58393603 11.67 ENSRNOT00000080082
DnaJ heat shock protein family (Hsp40) member B5
chr14_-_80130139 11.56 ENSRNOT00000091652
ENSRNOT00000010482
actin binding LIM protein family, member 2
chr14_-_34115273 11.51 ENSRNOT00000032156
centrosomal protein 135
chr3_+_18315320 11.07 ENSRNOT00000006954

chr3_+_19772056 10.54 ENSRNOT00000044455

chr2_+_40000313 9.94 ENSRNOT00000014270
DEP domain containing 1B
chr1_-_100537377 9.78 ENSRNOT00000026599
Spi-B transcription factor
chr10_+_47412582 9.36 ENSRNOT00000003139
TNF receptor superfamily member 13B
chr8_-_39190457 9.09 ENSRNOT00000090161
STT3A, catalytic subunit of the oligosaccharyltransferase complex
chr8_-_48850671 9.06 ENSRNOT00000016580
C-X-C motif chemokine receptor 5
chr3_-_16750564 8.69 ENSRNOT00000084111

chr6_-_143702033 8.55 ENSRNOT00000051410

chr5_+_126670825 8.12 ENSRNOT00000012201
cytochrome b5 reductase-like
chr10_+_17486579 8.06 ENSRNOT00000080404
serine/threonine kinase 10
chr10_-_40489808 7.44 ENSRNOT00000037274
solute carrier family 36, member 3
chr4_+_145489869 7.44 ENSRNOT00000082618
Fanconi anemia, complementation group D2
chr4_-_60358562 7.06 ENSRNOT00000018001
coiled-coil-helix-coiled-coil-helix domain containing 3
chr6_-_138640187 7.03 ENSRNOT00000087983

chr6_+_139345486 6.52 ENSRNOT00000081540

chr1_+_140602542 6.47 ENSRNOT00000085570
interferon stimulated exonuclease gene 20
chr7_-_74938663 6.41 ENSRNOT00000014333
F-box protein 43
chr1_-_24604400 6.41 ENSRNOT00000081175
RIKEN cDNA 1700020N01 gene
chr2_+_198655437 6.33 ENSRNOT00000028781
hemochromatosis type 2 (juvenile)
chr9_+_16530074 6.24 ENSRNOT00000091565
pre T-cell antigen receptor alpha
chr9_-_114152716 5.94 ENSRNOT00000044153

chr9_+_25304876 5.92 ENSRNOT00000065053
transcription factor AP-2 delta
chr6_-_128727374 5.86 ENSRNOT00000082152
spectrin repeat containing, nuclear envelope family member 3
chr9_-_114282799 5.77 ENSRNOT00000090539
uncharacterized LOC102555328
chr3_+_72395218 5.76 ENSRNOT00000057616
proteoglycan 3, pro eosinophil major basic protein 2
chr16_-_19349080 5.69 ENSRNOT00000038494
hematopoietic SH2 domain containing
chr4_-_164211819 5.60 ENSRNOT00000084796
hypothetical protein LOC497796
chr15_+_5319916 5.51 ENSRNOT00000046644
disks large homolog 5-like
chr7_-_27136652 5.51 ENSRNOT00000086905
host cell factor C2
chr6_-_125317593 5.50 ENSRNOT00000074142
ovarian cancer G-protein coupled receptor 1-like
chr17_+_28504623 5.48 ENSRNOT00000021568
coagulation factor XIII A1 chain
chr10_+_4945911 5.48 ENSRNOT00000003420
protamine 1
chr4_-_103646906 5.45 ENSRNOT00000047620

chr9_+_42871950 5.38 ENSRNOT00000089673
AT-rich interaction domain 5A
chr2_+_122368265 5.38 ENSRNOT00000078321
ATPase phospholipid transporting 11B (putative)
chr6_+_52265930 5.23 ENSRNOT00000087513
ENSRNOT00000067849
synaptophysin-like 1
chr6_-_124876710 5.23 ENSRNOT00000073530
G protein-coupled receptor 68
chr14_-_21709084 5.22 ENSRNOT00000087477
submaxillary gland androgen regulated protein 3B
chr10_+_56591292 5.21 ENSRNOT00000023379
CTD nuclear envelope phosphatase 1
chr4_-_130659697 5.20 ENSRNOT00000072374
rCG56280-like
chr9_-_16820983 5.20 ENSRNOT00000083886
DMRT-like family C2
chr6_-_142676432 5.07 ENSRNOT00000074947

chr8_+_80662762 4.93 ENSRNOT00000057689
60S ribosomal protein L27-like
chr7_+_120202601 4.87 ENSRNOT00000082862

chr1_+_140601791 4.80 ENSRNOT00000091588
interferon stimulated exonuclease gene 20
chr3_+_16590244 4.72 ENSRNOT00000073229

chr1_+_81736335 4.47 ENSRNOT00000027242
doublesex- and mab-3-related transcription factor C2-like
chr12_+_25498198 4.45 ENSRNOT00000076916
neutrophil cytosolic factor 1
chr3_-_72895740 4.44 ENSRNOT00000012568
fatty acid desaturase 2-like 1
chr2_+_123790915 4.38 ENSRNOT00000023282
adenosine deaminase domain containing 1
chr15_+_57221292 4.33 ENSRNOT00000014502
lymphocyte cytosolic protein 1
chr5_+_156439633 4.31 ENSRNOT00000090232
eukaryotic translation initiation factor 4 gamma, 3
chr19_-_55423052 4.29 ENSRNOT00000019528
ENSRNOT00000079641
galactosamine (N-acetyl)-6-sulfatase
chr8_+_60760078 4.27 ENSRNOT00000063930
proline-serine-threonine phosphatase-interacting protein 1
chr5_+_155794229 4.27 ENSRNOT00000018127
hypothetical protein LOC690206
chr4_+_79868442 4.20 ENSRNOT00000089973
membrane palmitoylated protein 6
chr8_+_53411316 4.19 ENSRNOT00000011107
ENSRNOT00000086957
transmembrane protease, serine 5
chr4_-_68349273 4.18 ENSRNOT00000016251
protease, serine, 37
chr7_-_117259141 4.17 ENSRNOT00000040762
plectin
chr19_-_24875137 4.09 ENSRNOT00000006152
adhesion G protein-coupled receptor E5
chr10_-_103590607 4.07 ENSRNOT00000034741
Cd300 molecule-like family member E
chr11_+_64472072 4.06 ENSRNOT00000042756
similar to ribosomal protein L27
chr7_-_117259791 4.03 ENSRNOT00000086550
plectin
chr18_+_3565166 4.01 ENSRNOT00000039377
RIO kinase 3
chr12_-_2843772 3.97 ENSRNOT00000061750
CD209c molecule
chr3_-_7203420 3.92 ENSRNOT00000015236
growth factor independent 1B transcriptional repressor
chr12_+_37211316 3.85 ENSRNOT00000032739
coiled-coil domain containing 92
chr19_+_42097995 3.80 ENSRNOT00000020197
haptoglobin
chr10_+_110445797 3.80 ENSRNOT00000054920
nuclear prelamin A recognition factor
chr16_+_68586235 3.76 ENSRNOT00000039592
uncharacterized LOC103693984
chr6_-_143206772 3.75 ENSRNOT00000073713

chr19_-_23554594 3.74 ENSRNOT00000004590
interleukin 15
chr2_+_248219428 3.69 ENSRNOT00000037181
similar to guanylate binding protein family, member 6
chr9_+_10061978 3.53 ENSRNOT00000075180
alkaline ceramidase 1
chr2_-_27364906 3.50 ENSRNOT00000078639
DNA polymerase kappa
chr8_-_14373894 3.49 ENSRNOT00000011883
melatonin receptor 1B
chr1_-_48070536 3.49 ENSRNOT00000020070
MAS1 proto-oncogene like, G protein-coupled receptor
chr3_+_149144795 3.42 ENSRNOT00000015482
DNA methyltransferase 3 beta
chr2_+_210668403 3.37 ENSRNOT00000074806
EPS8-like 3
chr1_-_173180745 3.36 ENSRNOT00000043904
olfactory receptor 203
chr13_-_27653839 3.35 ENSRNOT00000071638
signal-regulatory protein alpha-like
chrX_-_14783792 3.29 ENSRNOT00000087609
similar to ferritin, heavy polypeptide-like 17
chr17_+_9639330 3.14 ENSRNOT00000018232
docking protein 3
chr20_+_4162055 3.13 ENSRNOT00000081236
butyrophilin-like 3
chr18_-_11906827 3.08 ENSRNOT00000078207
desmocollin 1
chr10_-_2229493 3.03 ENSRNOT00000047732
similar to 40S ribosomal protein S19
chr14_+_39368530 3.03 ENSRNOT00000084367
cytochrome c oxidase subunit 7B2
chr6_+_110749705 3.01 ENSRNOT00000084348
leucine rich repeat containing 74A
chr20_-_2734296 3.01 ENSRNOT00000082285
butyrophilin-like 5
chr7_-_122340943 3.00 ENSRNOT00000078345
megakaryoblastic leukemia (translocation) 1
chr1_+_212714179 3.00 ENSRNOT00000054880
ENSRNOT00000025680
olfactory receptor 292
chr4_-_132111079 2.96 ENSRNOT00000013719
eukaryotic translation initiation factor 4E family member 3
chr17_-_22863966 2.93 ENSRNOT00000046157
transmembrane protein 170B
chr5_+_33097654 2.89 ENSRNOT00000008087
cyclic nucleotide gated channel beta 3
chr10_+_103562725 2.88 ENSRNOT00000075199

chrX_-_77675487 2.85 ENSRNOT00000042799
cysteinyl leukotriene receptor 1
chrX_+_158351156 2.83 ENSRNOT00000080538
protein FAM122B-like
chr14_-_37763712 2.81 ENSRNOT00000030610
zygote arrest 1
chr3_+_33641616 2.80 ENSRNOT00000051953
enhancer of polycomb homolog 2
chr7_+_143092511 2.79 ENSRNOT00000084223
similar to RIKEN cDNA 1700011A15
chr9_-_14706557 2.79 ENSRNOT00000048975
triggering receptor expressed on myeloid cells-like 4
chr2_-_57600820 2.78 ENSRNOT00000083247
NIPBL, cohesin loading factor
chr1_-_266862842 2.76 ENSRNOT00000027496
up-regulated during skeletal muscle growth protein 5
chr2_+_80948658 2.74 ENSRNOT00000074689
dynein, axonemal, heavy chain 5
chr17_+_15194262 2.73 ENSRNOT00000073070

chr3_+_21555341 2.72 ENSRNOT00000030332

chr15_+_24141651 2.70 ENSRNOT00000082304
galectin 3
chr8_-_48762342 2.67 ENSRNOT00000049125
forkhead box R1
chr2_-_246737997 2.65 ENSRNOT00000021719
pyruvate dehydrogenase (lipoamide) alpha 2
chr15_+_30750093 2.64 ENSRNOT00000071830

chr4_+_95884743 2.63 ENSRNOT00000008585
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1`
chr8_-_76239995 2.61 ENSRNOT00000071321
60S ribosomal protein L27-like
chr19_-_20508711 2.58 ENSRNOT00000032408
hypothetical protein LOC680913
chr1_-_66645214 2.58 ENSRNOT00000084168
eukaryotic translation initiation factor 3, subunit 6 48kDa-like
chr14_+_16924960 2.58 ENSRNOT00000003009
coiled-coil domain containing 158
chr17_+_25228437 2.54 ENSRNOT00000072904

chr8_-_105088401 2.51 ENSRNOT00000073068
40S ribosomal protein S17-like
chr3_+_149466770 2.46 ENSRNOT00000065104
BPI fold containing family A, member 6
chr2_-_80293181 2.45 ENSRNOT00000016111
OTU deubiquitinase with linear linkage specificity
chr11_-_47122095 2.44 ENSRNOT00000002194
ribosomal protein L24
chr10_-_29196563 2.42 ENSRNOT00000005205
fatty acid binding protein 6
chr2_+_219628695 2.36 ENSRNOT00000067324
SAS-6 centriolar assembly protein
chr5_-_2803855 2.33 ENSRNOT00000009490
ribosomal protein S8-like
chr14_+_107767392 2.28 ENSRNOT00000012847
chaperonin containing TCP1 subunit 4
chrX_+_106230013 2.26 ENSRNOT00000067828

chr2_+_87418517 2.23 ENSRNOT00000048046
tyrosine-protein phosphatase non-receptor type substrate 1-like
chr3_+_172195844 2.22 ENSRNOT00000034915
aminopeptidase-like 1
chr20_-_7208292 2.21 ENSRNOT00000083169
nudix hydrolase 3
chr14_-_14390699 2.19 ENSRNOT00000046639
annexin A3
chr20_-_46215120 2.18 ENSRNOT00000000336
sphingomyelin phosphodiesterase 2
chr1_+_248195797 2.17 ENSRNOT00000066891
tumor protein D55-like
chr7_-_54823956 2.17 ENSRNOT00000073180
GLI pathogenesis-related 1 like 2
chr13_+_48455923 2.12 ENSRNOT00000009280
Rab7b, member RAS oncogene family
chr3_+_149221377 2.07 ENSRNOT00000016220
ENSRNOT00000087752
microtubule-associated protein, RP/EB family, member 1
chr16_+_9907598 2.07 ENSRNOT00000027352
protein tyrosine phosphatase, non-receptor type 20
chrX_-_123980357 2.03 ENSRNOT00000049435
reproductive homeobox 8
chr1_-_124803363 2.03 ENSRNOT00000066380
Kruppel-like factor 13
chr7_+_70612103 2.01 ENSRNOT00000057833
Rho GTPase activating protein 9
chr2_-_35532285 1.99 ENSRNOT00000090178
olfactory receptor 150-like
chr13_+_51218468 1.98 ENSRNOT00000033636
similar to UDP-N-acetylglucosamine:a-1,3-D-mannoside beta-1,4-N-acetylgluco
chr1_+_167539036 1.98 ENSRNOT00000093112
ribonucleotide reductase catalytic subunit M1
chrX_-_23187341 1.96 ENSRNOT00000000180
5'-aminolevulinate synthase 2
chr11_-_31805728 1.95 ENSRNOT00000032162
phosphoribosylglycinamide formyltransferase
chr3_+_159095876 1.94 ENSRNOT00000074363
seminal vesicle secretory protein 4
chrX_+_63520991 1.91 ENSRNOT00000071590
apolipoprotein O
chr3_-_149563476 1.88 ENSRNOT00000071869

chr2_+_155076464 1.88 ENSRNOT00000057619
similar to GTPase activating protein testicular GAP1
chr6_-_26318568 1.80 ENSRNOT00000072707
titin-like
chr13_+_77940454 1.80 ENSRNOT00000003460
mitochondrial ribosomal protein S14
chr16_-_54628458 1.73 ENSRNOT00000042587
ADAM metallopeptidase domain 24
chr2_-_202470399 1.72 ENSRNOT00000026726
WD repeat domain 3
chr20_-_2858205 1.71 ENSRNOT00000085662
butyrophilin-like 8
chr10_+_43067299 1.67 ENSRNOT00000003447
polypeptide N-acetylgalactosaminyltransferase 10
chr2_+_115225356 1.67 ENSRNOT00000073329
olfactory receptor 149-like
chr17_-_89163113 1.66 ENSRNOT00000050445
ribosomal protein S19-like
chr2_+_115092263 1.66 ENSRNOT00000064455
olfactory receptor 150-like
chr19_+_25123724 1.63 ENSRNOT00000007407
hypothetical protein LOC686013
chr10_-_15928169 1.62 ENSRNOT00000028069
neuron specific gene family member 2
chr1_-_173528943 1.62 ENSRNOT00000020393
NLR family, pyrin domain containing 10
chr1_-_7726401 1.61 ENSRNOT00000021524
peroxisomal biogenesis factor 3
chr16_+_6035926 1.59 ENSRNOT00000020284
selenoprotein K
chr19_-_41433346 1.58 ENSRNOT00000022952
cap methyltransferase 2
chr5_+_126511350 1.54 ENSRNOT00000011408
single stranded DNA binding protein 3
chr20_-_5927070 1.53 ENSRNOT00000059264
solute carrier family 26 member 8
chr15_-_46297243 1.51 ENSRNOT00000088793

chr5_+_78267248 1.50 ENSRNOT00000019910
pre-mRNA processing factor 4
chr8_-_130550388 1.50 ENSRNOT00000026355
cytochrome P450, family 8, subfamily b, polypeptide 1
chr4_-_179700130 1.49 ENSRNOT00000021306
lamin tail domain containing 1
chr7_-_130107437 1.48 ENSRNOT00000055865
histone deacetylase 10
chr1_+_61314070 1.47 ENSRNOT00000077642
zinc finger protein 54
chr1_+_167538744 1.46 ENSRNOT00000093070
ribonucleotide reductase catalytic subunit M1
chr5_+_173318479 1.42 ENSRNOT00000026725
integrator complex subunit 11
chr10_-_34439470 1.40 ENSRNOT00000072081
butyrophilin-like 9
chr12_+_660011 1.38 ENSRNOT00000040830
PDS5 cohesin associated factor B
chr17_+_66548818 1.34 ENSRNOT00000024361
anillin, actin binding protein-like 1
chr19_-_39646693 1.33 ENSRNOT00000019104
proteasome 26S subunit, non-ATPase 7
chr1_+_148862493 1.29 ENSRNOT00000073451
olfactory receptor 10A5-like
chr4_-_1752548 1.28 ENSRNOT00000071677
olfactory receptor 150-like
chr8_+_78872102 1.26 ENSRNOT00000090047
zinc finger protein 280D
chr4_-_176679815 1.26 ENSRNOT00000090122
glycogen synthase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Tgif2_Tgif2lx1_Tgif2lx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.9 35.6 GO:2001288 detection of muscle stretch(GO:0035995) positive regulation of caveolin-mediated endocytosis(GO:2001288)
5.3 31.7 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
3.8 23.0 GO:0002074 extraocular skeletal muscle development(GO:0002074)
3.8 11.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
3.7 33.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
2.8 25.5 GO:0060297 regulation of sarcomere organization(GO:0060297)
1.9 5.8 GO:0045575 basophil activation(GO:0045575)
1.7 5.2 GO:1900114 positive regulation of histone H3-K9 dimethylation(GO:1900111) positive regulation of histone H3-K9 trimethylation(GO:1900114)
1.5 4.5 GO:0070946 neutrophil mediated killing of gram-positive bacterium(GO:0070946)
1.3 70.9 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
1.3 5.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
1.3 9.1 GO:0043686 co-translational protein modification(GO:0043686)
1.3 3.8 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
1.2 3.7 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350) regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
1.2 3.5 GO:0030824 negative regulation of cGMP metabolic process(GO:0030824)
1.1 5.7 GO:1904180 negative regulation of membrane depolarization(GO:1904180)
1.1 3.4 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
1.1 7.4 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
1.0 4.0 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
1.0 11.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.9 7.4 GO:0015808 L-alanine transport(GO:0015808)
0.9 2.8 GO:0035261 external genitalia morphogenesis(GO:0035261) gall bladder development(GO:0061010)
0.9 2.7 GO:1903769 negative regulation of cell proliferation in bone marrow(GO:1903769)
0.9 3.5 GO:0010446 response to alkaline pH(GO:0010446)
0.9 4.3 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.8 2.5 GO:1990108 protein linear deubiquitination(GO:1990108)
0.7 5.9 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.7 2.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.7 2.1 GO:1904528 positive regulation of microtubule binding(GO:1904528)
0.7 5.5 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.7 15.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.7 12.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.6 38.2 GO:0042398 cellular modified amino acid biosynthetic process(GO:0042398)
0.6 2.4 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.6 3.5 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.6 2.3 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.6 9.0 GO:0042407 cristae formation(GO:0042407)
0.6 2.8 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.6 2.2 GO:1901907 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.5 6.4 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.5 1.6 GO:0036451 cap mRNA methylation(GO:0036451)
0.5 9.1 GO:0048535 lymph node development(GO:0048535)
0.5 2.0 GO:1901423 response to benzene(GO:1901423)
0.5 3.9 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
0.5 6.2 GO:0070244 negative regulation of thymocyte apoptotic process(GO:0070244)
0.5 9.5 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.4 1.7 GO:0060468 prevention of polyspermy(GO:0060468)
0.4 8.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.4 0.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.4 1.6 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.4 6.3 GO:0016540 protein autoprocessing(GO:0016540)
0.4 1.2 GO:0033986 response to methanol(GO:0033986)
0.4 9.4 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.4 3.0 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.3 1.6 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.3 9.8 GO:0030225 macrophage differentiation(GO:0030225)
0.3 7.8 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.3 4.3 GO:0051764 actin crosslink formation(GO:0051764)
0.3 3.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.3 1.5 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.3 3.3 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 9.6 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.2 2.6 GO:0070933 histone H4 deacetylation(GO:0070933)
0.2 2.6 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.2 2.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 2.7 GO:0021670 lateral ventricle development(GO:0021670)
0.2 0.7 GO:0090625 siRNA loading onto RISC involved in RNA interference(GO:0035087) mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.2 1.1 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.2 0.5 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.2 0.3 GO:0045959 negative regulation of complement activation, classical pathway(GO:0045959)
0.2 1.7 GO:0016266 O-glycan processing(GO:0016266)
0.2 3.0 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.2 5.5 GO:0030261 chromosome condensation(GO:0030261)
0.2 2.2 GO:0043312 neutrophil degranulation(GO:0043312)
0.2 4.4 GO:0045332 phospholipid translocation(GO:0045332)
0.1 2.6 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 4.2 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 0.4 GO:0036115 medium-chain fatty-acyl-CoA metabolic process(GO:0036112) fatty-acyl-CoA catabolic process(GO:0036115)
0.1 0.5 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 13.2 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.1 1.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 10.7 GO:0006986 response to unfolded protein(GO:0006986)
0.1 0.6 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.4 GO:2000669 neutrophil clearance(GO:0097350) negative regulation of dendritic cell apoptotic process(GO:2000669)
0.1 2.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.0 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.1 4.0 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 0.9 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 5.2 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.1 1.5 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 0.8 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1 1.5 GO:0019532 oxalate transport(GO:0019532) sulfate transmembrane transport(GO:1902358)
0.1 0.3 GO:1904937 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.1 2.4 GO:0007099 centriole replication(GO:0007099)
0.1 2.4 GO:0008206 bile acid metabolic process(GO:0008206)
0.1 5.9 GO:0030901 midbrain development(GO:0030901)
0.1 0.8 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.1 1.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 1.1 GO:0006020 inositol metabolic process(GO:0006020)
0.1 1.4 GO:0016180 snRNA processing(GO:0016180)
0.1 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.8 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.3 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 2.2 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 4.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.1 GO:0031050 dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918)
0.0 4.3 GO:0006413 translational initiation(GO:0006413)
0.0 0.3 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 3.9 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 1.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 1.3 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 3.8 GO:0007050 cell cycle arrest(GO:0007050)
0.0 4.4 GO:0007286 spermatid development(GO:0007286)
0.0 0.5 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.0 0.1 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
0.0 0.7 GO:0018149 peptide cross-linking(GO:0018149)
0.0 1.5 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 103.2 GO:0031430 M band(GO:0031430)
1.9 35.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
1.3 9.0 GO:0061617 MICOS complex(GO:0061617)
1.1 6.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
1.0 3.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.9 3.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.8 5.9 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.7 2.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.7 43.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.6 2.4 GO:0098536 deuterosome(GO:0098536)
0.5 9.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.5 9.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.5 5.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.5 1.5 GO:0071001 U4/U6 snRNP(GO:0071001)
0.5 2.5 GO:0071797 LUBAC complex(GO:0071797)
0.5 3.8 GO:0005638 lamin filament(GO:0005638)
0.5 4.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.5 2.7 GO:0036157 outer dynein arm(GO:0036157)
0.4 4.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.4 8.2 GO:0016528 sarcoplasm(GO:0016528)
0.4 25.5 GO:0014704 intercalated disc(GO:0014704)
0.3 2.6 GO:0033290 eukaryotic 43S preinitiation complex(GO:0016282) eukaryotic 48S preinitiation complex(GO:0033290)
0.3 2.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.3 1.7 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.3 5.2 GO:0001741 XY body(GO:0001741)
0.3 2.6 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.3 21.7 GO:0072686 mitotic spindle(GO:0072686)
0.2 11.9 GO:0015030 Cajal body(GO:0015030)
0.2 3.1 GO:0030057 desmosome(GO:0030057)
0.2 5.2 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 1.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2 2.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.2 3.0 GO:0045277 respiratory chain complex IV(GO:0045277)
0.2 4.3 GO:0001891 phagocytic cup(GO:0001891)
0.1 15.4 GO:0005814 centriole(GO:0005814)
0.1 2.2 GO:0042581 specific granule(GO:0042581)
0.1 0.7 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 2.7 GO:0097386 glial cell projection(GO:0097386)
0.1 0.9 GO:0042587 glycogen granule(GO:0042587)
0.1 1.6 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 3.0 GO:0035861 site of double-strand break(GO:0035861)
0.1 1.4 GO:0032039 integrator complex(GO:0032039)
0.1 32.2 GO:0005667 transcription factor complex(GO:0005667)
0.1 3.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 0.8 GO:0031045 dense core granule(GO:0031045)
0.1 3.7 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287)
0.1 5.5 GO:0000786 nucleosome(GO:0000786)
0.1 1.8 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 1.2 GO:0005682 U5 snRNP(GO:0005682)
0.1 1.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 16.4 GO:0016607 nuclear speck(GO:0016607)
0.0 2.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.9 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.8 GO:0044216 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 4.8 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 5.4 GO:0055037 recycling endosome(GO:0055037)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 3.5 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 9.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.2 GO:0005901 caveola(GO:0005901)
0.0 1.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 2.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.8 GO:0031902 late endosome membrane(GO:0031902)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 35.3 GO:0004111 creatine kinase activity(GO:0004111)
4.5 35.6 GO:0071253 connexin binding(GO:0071253)
3.9 70.0 GO:0005523 tropomyosin binding(GO:0005523)
2.6 33.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
2.3 11.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
2.0 15.9 GO:0016151 nickel cation binding(GO:0016151)
1.8 25.5 GO:0031432 titin binding(GO:0031432)
1.5 7.4 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
1.1 6.3 GO:0098821 BMP receptor activity(GO:0098821)
1.0 9.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.9 20.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.9 12.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.8 4.0 GO:0089720 caspase binding(GO:0089720)
0.7 3.5 GO:0008502 melatonin receptor activity(GO:0008502)
0.7 3.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.7 2.6 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.7 2.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.6 3.9 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.6 9.1 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.6 1.9 GO:0016882 cyclo-ligase activity(GO:0016882)
0.6 9.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.6 3.5 GO:0017040 ceramidase activity(GO:0017040)
0.6 2.9 GO:0004974 leukotriene receptor activity(GO:0004974)
0.6 2.8 GO:0036033 mediator complex binding(GO:0036033)
0.6 2.2 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.5 5.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.5 3.8 GO:0030492 hemoglobin binding(GO:0030492)
0.5 2.7 GO:0050785 advanced glycation end-product receptor activity(GO:0050785)
0.5 1.6 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.5 4.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.4 2.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.4 7.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.4 4.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.3 6.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 2.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.3 4.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.3 1.1 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.3 2.4 GO:0032052 bile acid binding(GO:0032052)
0.2 8.2 GO:0030506 structural constituent of muscle(GO:0008307) ankyrin binding(GO:0030506)
0.2 2.9 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.2 3.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 9.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 0.9 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.2 3.8 GO:0005521 lamin binding(GO:0005521)
0.2 5.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 4.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 1.5 GO:0030621 U6 snRNA binding(GO:0017070) U4 snRNA binding(GO:0030621)
0.2 1.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.2 11.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 3.3 GO:0008199 ferric iron binding(GO:0008199)
0.2 1.5 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 1.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 0.8 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.2 1.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 13.9 GO:0051082 unfolded protein binding(GO:0051082)
0.1 32.0 GO:0001047 core promoter binding(GO:0001047)
0.1 7.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 3.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.5 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 1.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 3.0 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 2.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 3.1 GO:0005158 insulin receptor binding(GO:0005158)
0.1 6.6 GO:0032947 protein complex scaffold(GO:0032947)
0.1 1.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.3 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.2 GO:0031013 troponin I binding(GO:0031013)
0.1 1.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 1.7 GO:0030515 snoRNA binding(GO:0030515)
0.0 1.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 2.2 GO:0030145 manganese ion binding(GO:0030145)
0.0 5.6 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.8 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 9.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 5.2 GO:0005179 hormone activity(GO:0005179)
0.0 3.8 GO:0004386 helicase activity(GO:0004386)
0.0 2.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 2.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.9 GO:0043621 protein self-association(GO:0043621)
0.0 1.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 3.8 GO:0005125 cytokine activity(GO:0005125)
0.0 3.0 GO:0051015 actin filament binding(GO:0051015)
0.0 1.5 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.0 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 2.0 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 1.0 GO:0043130 ubiquitin binding(GO:0043130)
0.0 1.2 GO:0001948 glycoprotein binding(GO:0001948)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 31.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.5 35.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.5 36.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.2 9.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 5.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 7.4 PID BARD1 PATHWAY BARD1 signaling events
0.1 6.3 PID BMP PATHWAY BMP receptor signaling
0.1 4.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.9 PID CONE PATHWAY Visual signal transduction: Cones
0.1 2.7 PID RAS PATHWAY Regulation of Ras family activation
0.1 4.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.8 PID RHOA PATHWAY RhoA signaling pathway
0.1 2.1 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 21.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 3.4 PID E2F PATHWAY E2F transcription factor network
0.0 2.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 2.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.9 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.5 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 31.7 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.9 16.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.9 33.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.7 7.4 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.5 22.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.4 4.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 8.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 1.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 3.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 2.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 2.9 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.2 2.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 3.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 13.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 11.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 9.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 1.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 2.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 22.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 26.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 6.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 2.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 7.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 4.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 9.1 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.1 3.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 0.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.1 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 0.6 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 2.7 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 0.8 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 1.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.3 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 4.0 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 1.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 2.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.3 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 1.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+