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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Tfcp2l1

Z-value: 0.53

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Transcription factors associated with Tfcp2l1

Gene Symbol Gene ID Gene Info
Tfcp2l1
ENSRNOG00000002414 transcription factor CP2-like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tfcp2l1rn6_v1_chr13_+_34610684_346106890.437.0e-16Click!

Activity profile of Tfcp2l1 motif

Sorted Z-values of Tfcp2l1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_105116916 16.18 ENSRNOT00000012373
Evpl
envoplakin
chr11_-_28527890 15.02 ENSRNOT00000002138
Cldn8
claudin 8
chr8_-_50231357 14.48 ENSRNOT00000081737
Tagln
transgelin
chr13_+_47454591 14.17 ENSRNOT00000005791
LOC498222
similar to specifically androgen-regulated protein
chr2_-_204254699 13.34 ENSRNOT00000021487
Mab21l3
mab-21 like 3
chr5_-_151824633 7.98 ENSRNOT00000043959
Sfn
stratifin
chr10_+_89251370 7.76 ENSRNOT00000076820
Aoc3
amine oxidase, copper containing 3
chr8_+_115151627 7.15 ENSRNOT00000064252
Abhd14b
abhydrolase domain containing 14b
chr7_-_139483997 6.64 ENSRNOT00000086062
Col2a1
collagen type II alpha 1 chain
chr2_-_195908037 6.42 ENSRNOT00000079776
Tuft1
tuftelin 1
chr20_+_5049496 6.42 ENSRNOT00000088251
ENSRNOT00000001118
Ddah2
dimethylarginine dimethylaminohydrolase 2
chr3_+_113319456 6.36 ENSRNOT00000051354
Ckmt1
creatine kinase, mitochondrial 1
chr1_+_264504591 5.78 ENSRNOT00000050076
Pax2
paired box 2
chr13_-_45318822 5.61 ENSRNOT00000091514
ENSRNOT00000005143
Cxcr4
C-X-C motif chemokine receptor 4
chr5_-_153924896 5.16 ENSRNOT00000065247
Grhl3
grainyhead-like transcription factor 3
chr10_+_63677396 4.98 ENSRNOT00000005100
Slc43a2
solute carrier family 43 member 2
chr8_+_85503224 4.98 ENSRNOT00000012348
Gsta4
glutathione S-transferase alpha 4
chr4_-_116278615 4.27 ENSRNOT00000020505
Cyp26b1
cytochrome P450, family 26, subfamily b, polypeptide 1
chr6_+_23757225 4.22 ENSRNOT00000005553
LOC298795
similar to 14-3-3 protein sigma
chr2_+_200572502 4.12 ENSRNOT00000074666
Zfp697
zinc finger protein 697
chr1_-_141481315 4.03 ENSRNOT00000020229
Pex11a
peroxisomal biogenesis factor 11 alpha
chr7_-_143228060 3.97 ENSRNOT00000088923
ENSRNOT00000012640
Krt75
keratin 75
chr11_+_39482408 3.79 ENSRNOT00000075126
Hmgn1
high mobility group nucleosome binding domain 1
chr17_+_30965942 3.54 ENSRNOT00000060143
Pxdc1
PX domain containing 1
chr3_+_170550314 3.48 ENSRNOT00000006991
Tfap2c
transcription factor AP-2 gamma
chr1_+_225129097 3.28 ENSRNOT00000026938
Eml3
echinoderm microtubule associated protein like 3
chr2_+_196334626 3.25 ENSRNOT00000050914
ENSRNOT00000028645
ENSRNOT00000090729
Sema6c
semaphorin 6C
chr8_-_21661259 3.22 ENSRNOT00000068308
Fbxl12
F-box and leucine-rich repeat protein 12
chr1_-_199037267 3.16 ENSRNOT00000078779
Ccdc189
coiled-coil domain containing 189
chr11_-_36479868 3.15 ENSRNOT00000075762
LOC100911295
non-histone chromosomal protein HMG-14-like
chr9_+_81518584 3.13 ENSRNOT00000084309
Arpc2
actin related protein 2/3 complex, subunit 2
chr9_+_81518176 3.07 ENSRNOT00000078317
ENSRNOT00000019265
ENSRNOT00000088246
ENSRNOT00000084682
Arpc2
actin related protein 2/3 complex, subunit 2
chr16_-_36080191 3.02 ENSRNOT00000017635
Hmgb2l1
high mobility group box 2-like 1
chr3_+_176691329 2.98 ENSRNOT00000017319
Ppdpf
pancreatic progenitor cell differentiation and proliferation factor
chr9_+_81672758 2.91 ENSRNOT00000020646
Ctdsp1
CTD small phosphatase 1
chr1_+_199323628 2.85 ENSRNOT00000036187
Zfp646
zinc finger protein 646
chr3_+_161236898 2.62 ENSRNOT00000082303
ENSRNOT00000020323
Ube2c
ubiquitin-conjugating enzyme E2C
chr7_-_61798729 2.48 ENSRNOT00000010283
Dyrk2
dual specificity tyrosine phosphorylation regulated kinase 2
chr10_-_57837602 2.41 ENSRNOT00000075185
Nlrp1b
NLR family, pyrin domain containing 1B
chr7_+_79138925 2.40 ENSRNOT00000047511
AABR07057586.1

chr1_+_44446765 2.35 ENSRNOT00000030132
Cldn20
claudin 20
chr5_-_58124681 2.23 ENSRNOT00000019795
Sigmar1
sigma non-opioid intracellular receptor 1
chr11_-_14741563 2.23 ENSRNOT00000002152
Nrip1
nuclear receptor interacting protein 1
chr13_+_52854031 2.19 ENSRNOT00000013738
ENSRNOT00000086004
Tmem9
transmembrane protein 9
chr20_+_3553455 2.13 ENSRNOT00000090080
Ddr1
discoidin domain receptor tyrosine kinase 1
chr10_-_64862268 2.06 ENSRNOT00000056234
Phf12
PHD finger protein 12
chr6_-_9459188 2.03 ENSRNOT00000019894
Srbd1
S1 RNA binding domain 1
chr11_+_36075709 2.01 ENSRNOT00000002247
Ets2
ETS proto-oncogene 2, transcription factor
chr4_+_145427367 1.94 ENSRNOT00000037788
Il17rc
interleukin 17 receptor C
chr3_+_120726906 1.93 ENSRNOT00000051069
Bcl2l11
BCL2 like 11
chr10_-_92476109 1.87 ENSRNOT00000089029
Kansl1
KAT8 regulatory NSL complex subunit 1
chr9_-_20195566 1.83 ENSRNOT00000015223
Adgrf5
adhesion G protein-coupled receptor F5
chr10_-_90265017 1.78 ENSRNOT00000064283
ENSRNOT00000048418
Ubtf
upstream binding transcription factor, RNA polymerase I
chr8_+_116754178 1.77 ENSRNOT00000068295
ENSRNOT00000084429
Uba7
ubiquitin-like modifier activating enzyme 7
chr6_+_42852683 1.76 ENSRNOT00000079185
Odc1
ornithine decarboxylase 1
chr1_-_225128740 1.74 ENSRNOT00000026897
Rom1
retinal outer segment membrane protein 1
chr10_+_59893067 1.62 ENSRNOT00000056443
Spata22
spermatogenesis associated 22
chr10_+_87759769 1.60 ENSRNOT00000017378
ENSRNOT00000046526
Krtap9-1
keratin associated protein 9-1
chr15_-_33285779 1.60 ENSRNOT00000036150
Cdh24
cadherin 24
chr2_+_199199845 1.56 ENSRNOT00000020932
LOC100909441
tubulin alpha-1C chain-like
chr14_-_91904433 1.53 ENSRNOT00000005857
Fignl1
fidgetin-like 1
chr19_+_32188267 1.45 ENSRNOT00000025079
Smad1
SMAD family member 1
chr10_+_106712127 1.27 ENSRNOT00000040629
Tnrc6c
trinucleotide repeat containing 6C
chr5_-_164747083 1.21 ENSRNOT00000010433
Plod1
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr11_+_74050166 1.20 ENSRNOT00000002348
Lrrc15
leucine rich repeat containing 15
chr3_-_8659102 1.08 ENSRNOT00000050908
Zdhhc12
zinc finger, DHHC-type containing 12
chr8_+_71719563 1.05 ENSRNOT00000022828
Ppib
peptidylprolyl isomerase B
chr20_-_12820466 1.03 ENSRNOT00000001699
Ftcd
formimidoyltransferase cyclodeaminase
chr5_-_152198813 1.01 ENSRNOT00000082953
Hmgn2
high mobility group nucleosomal binding domain 2
chr1_-_164205222 0.99 ENSRNOT00000035774
Mogat2
monoacylglycerol O-acyltransferase 2
chr14_+_108007724 0.87 ENSRNOT00000014062
Xpo1
exportin 1
chr9_+_47281961 0.85 ENSRNOT00000065234
Slc9a4
solute carrier family 9 member A4
chr11_-_28777603 0.81 ENSRNOT00000002132
Krtap14
keratin associated protein 14
chr11_-_82860977 0.79 ENSRNOT00000002382
Polr2h
RNA polymerase II subunit H
chr15_+_34552410 0.78 ENSRNOT00000027802
Khnyn
KH and NYN domain containing
chr10_+_66509107 0.73 ENSRNOT00000017230
RGD1565317
similar to ubiquitin-like/S30 ribosomal fusion protein
chr10_-_87510629 0.71 ENSRNOT00000084197
Krtap1-3
keratin associated protein 1-3
chr19_+_57650163 0.65 ENSRNOT00000038257
ENSRNOT00000083572
Sprtn
SprT-like N-terminal domain
chr10_-_110555629 0.64 ENSRNOT00000054918
ENSRNOT00000088474
Wdr45b
WD repeat domain 45B
chr3_+_150055749 0.63 ENSRNOT00000055335
Actl10
actin-like 10
chr16_-_32421005 0.62 ENSRNOT00000082712
Nek1
NIMA-related kinase 1
chr6_+_86131242 0.55 ENSRNOT00000039337
Fau
FAU, ubiquitin like and ribosomal protein S30 fusion
chr10_-_110101872 0.53 ENSRNOT00000071893
Ccdc57
coiled-coil domain containing 57
chr10_+_87788458 0.53 ENSRNOT00000042020
LOC100910814
keratin-associated protein 9-1-like
chr15_-_56970365 0.45 ENSRNOT00000047192
Lrch1
leucine rich repeats and calponin homology domain containing 1
chr4_+_130332076 0.43 ENSRNOT00000083127
Mitf
melanogenesis associated transcription factor
chr7_-_114590119 0.40 ENSRNOT00000079599
Ptk2
protein tyrosine kinase 2
chr1_-_65701867 0.35 ENSRNOT00000006118
Zfp128
zinc finger protein 128
chr6_-_142353308 0.29 ENSRNOT00000066416
AABR07065814.2

chr6_-_125812517 0.24 ENSRNOT00000007061
Trip11
thyroid hormone receptor interactor 11
chr10_+_87832743 0.24 ENSRNOT00000055286
Krtap31-1
keratin associated protein 31-1
chr20_+_3555135 0.16 ENSRNOT00000085380
Ddr1
discoidin domain receptor tyrosine kinase 1
chr10_-_87510360 0.00 ENSRNOT00000077126
Krtap1-3
keratin associated protein 1-3

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfcp2l1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0035566 regulation of metanephros size(GO:0035566)
1.6 6.2 GO:2000814 positive regulation of barbed-end actin filament capping(GO:2000814)
1.4 4.3 GO:1902809 cornification(GO:0070268) regulation of skeletal muscle fiber differentiation(GO:1902809)
1.4 5.6 GO:0035470 positive regulation of vascular wound healing(GO:0035470) response to ultrasound(GO:1990478)
1.3 4.0 GO:0044375 regulation of peroxisome size(GO:0044375)
1.3 8.0 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
1.3 3.8 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
1.1 6.6 GO:0071306 cellular response to vitamin E(GO:0071306)
0.7 2.2 GO:0001543 ovarian follicle rupture(GO:0001543)
0.7 2.6 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.6 1.8 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.6 3.5 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.5 2.0 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.5 6.4 GO:0006527 arginine catabolic process(GO:0006527)
0.5 1.9 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.4 7.8 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.4 1.2 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.4 16.2 GO:0018149 peptide cross-linking(GO:0018149)
0.4 2.5 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.4 1.8 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.3 1.0 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.3 5.2 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.3 1.0 GO:0015942 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) formamide metabolic process(GO:0043606)
0.3 1.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.3 5.0 GO:0009635 response to herbicide(GO:0009635)
0.3 1.8 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.3 3.0 GO:0006265 DNA topological change(GO:0006265)
0.2 2.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.2 1.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 1.6 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.2 2.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 1.8 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.2 1.2 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.1 1.9 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 0.9 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 5.0 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.1 0.4 GO:0007172 signal complex assembly(GO:0007172)
0.1 2.4 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.1 1.9 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.9 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 0.4 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 1.7 GO:0061298 camera-type eye photoreceptor cell differentiation(GO:0060219) retina vasculature development in camera-type eye(GO:0061298)
0.1 0.9 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 6.4 GO:0032091 negative regulation of protein binding(GO:0032091)
0.1 1.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 1.0 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.0 0.7 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 1.1 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.0 4.0 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 14.5 GO:0030855 epithelial cell differentiation(GO:0030855)
0.0 2.9 GO:0045665 negative regulation of neuron differentiation(GO:0045665)
0.0 1.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.2 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.6 15.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.6 16.2 GO:0001533 cornified envelope(GO:0001533)
0.6 6.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3 2.4 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.3 1.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 4.0 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2 1.0 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2 5.8 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.9 GO:0005642 annulate lamellae(GO:0005642)
0.1 2.1 GO:0016580 Sin3 complex(GO:0016580)
0.1 2.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 2.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.2 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 1.9 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 13.4 GO:0005769 early endosome(GO:0005769)
0.0 0.6 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 2.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 6.4 GO:0043204 perikaryon(GO:0043204)
0.0 1.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 11.0 GO:0000785 chromatin(GO:0000785)
0.0 2.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 2.2 GO:0005770 late endosome(GO:0005770)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 3.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 4.0 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 1.6 GO:0001650 fibrillar center(GO:0001650)
0.0 30.8 GO:0070062 extracellular exosome(GO:0070062)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0016403 dimethylargininase activity(GO:0016403)
1.4 4.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
1.1 6.6 GO:0042289 MHC class II protein binding(GO:0042289)
1.1 17.2 GO:0019215 intermediate filament binding(GO:0019215)
1.0 6.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.9 5.6 GO:0032027 myosin light chain binding(GO:0032027)
0.9 6.4 GO:0004111 creatine kinase activity(GO:0004111)
0.8 3.0 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.7 7.8 GO:0008131 primary amine oxidase activity(GO:0008131)
0.6 5.8 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.5 2.9 GO:0008420 CTD phosphatase activity(GO:0008420)
0.4 1.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.4 2.2 GO:0004985 opioid receptor activity(GO:0004985)
0.4 1.8 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.3 2.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.3 5.0 GO:0043295 glutathione binding(GO:0043295)
0.3 1.8 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.3 3.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 1.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 8.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 2.4 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.2 1.9 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.2 1.0 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.2 4.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 1.4 GO:0070878 primary miRNA binding(GO:0070878)
0.2 1.8 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.1 1.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 5.0 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 2.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 14.5 GO:0030674 protein binding, bridging(GO:0030674)
0.1 1.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.9 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 1.9 GO:0070840 dynein complex binding(GO:0070840)
0.1 8.0 GO:0051219 phosphoprotein binding(GO:0051219)
0.1 5.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 3.5 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 1.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 2.5 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.1 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 20.8 GO:0005198 structural molecule activity(GO:0005198)
0.0 1.0 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 3.5 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 3.3 GO:0008017 microtubule binding(GO:0008017)
0.0 0.4 GO:0070888 E-box binding(GO:0070888)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 19.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 6.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 7.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.2 2.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 20.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 1.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 1.4 PID ALK2 PATHWAY ALK2 signaling events
0.1 0.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 0.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 2.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 2.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 3.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.0 PID CMYB PATHWAY C-MYB transcription factor network
0.0 3.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID IL6 7 PATHWAY IL6-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.6 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.5 17.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 5.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 2.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.2 6.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 4.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 5.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 1.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 2.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.9 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 4.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex