ISMARA results: Tfcp2

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Tfcp2

Z-value: 0.81

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Transcription factors associated with Tfcp2

Gene Symbol	Gene ID	Gene Info
Tfcp2 NCBI RGD Ensembl	ENSRNOG00000032395	transcription factor CP2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Tfcp2	rn6_v1_chr7_-_142180794_142180794	0.55	6.7e-27	Click!

Activity profile of Tfcp2 motif

Sorted Z-values of Tfcp2 motif

Top targets:

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr5_+_133896141 Show fit	28.67	ENSRNOT00000011434	Pdzk1ip1 NCBI RGD Ensembl Show fit	PDZK1 interacting protein 1
chr19_-_11308740 Show fit	22.80	ENSRNOT00000067391	Mt2A NCBI RGD Ensembl Show fit	metallothionein 2A
chr2_-_225107283 Show fit	21.24	ENSRNOT00000055711	Slc44a3 NCBI RGD Ensembl Show fit	solute carrier family 44, member 3
chr9_+_27402381 Show fit	17.59	ENSRNOT00000077372	Gsta3 NCBI RGD Ensembl Show fit	glutathione S-transferase alpha 3
chr7_-_145154131 Show fit	15.99	ENSRNOT00000055271	Ppp1r1a NCBI RGD Ensembl Show fit	protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr20_+_20236151 Show fit	15.02	ENSRNOT00000079630	Ank3 NCBI RGD Ensembl Show fit	ankyrin 3
chr5_-_33892462 Show fit	14.80	ENSRNOT00000009334	Atp6v0d2 NCBI RGD Ensembl Show fit	ATPase H+ transporting V0 subunit D2
chr16_-_21348391 Show fit	13.65	ENSRNOT00000083537	Lpar2 NCBI RGD Ensembl Show fit	lysophosphatidic acid receptor 2
chr5_+_149077412 Show fit	13.59	ENSRNOT00000014666	Matn1 NCBI RGD Ensembl Show fit	matrilin 1, cartilage matrix protein
chr4_-_148845267 Show fit	13.57	ENSRNOT00000037397	Tmem72 NCBI RGD Ensembl Show fit	transmembrane protein 72

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfcp2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
3.3	22.8	GO:0048143	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016) astrocyte activation(GO:0048143)
1.1	20.0	GO:0046415	urate metabolic process(GO:0046415)
0.6	18.4	GO:0015991	ATP hydrolysis coupled proton transport(GO:0015991)
5.9	17.6	GO:0046223	toxin catabolic process(GO:0009407) mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) secondary metabolite catabolic process(GO:0090487) organic heteropentacyclic compound catabolic process(GO:1901377)
0.2	17.5	GO:0044042	glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
1.3	16.7	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
2.8	16.6	GO:0010966	regulation of phosphate transport(GO:0010966)
3.1	15.5	GO:0036233	glycine import(GO:0036233)
3.8	15.0	GO:1900827	positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1	14.4	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)

Showing 1 to 10 of 130 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	36.3	GO:0005887	integral component of plasma membrane(GO:0005887)
0.0	24.2	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.2	17.7	GO:0005604	basement membrane(GO:0005604)
0.1	16.5	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
1.5	15.0	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
1.1	14.8	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1	13.2	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.7	11.8	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.1	11.8	GO:0005901	caveola(GO:0005901)
0.1	9.9	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)

Showing 1 to 10 of 77 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
2.7	29.9	GO:0046870	cadmium ion binding(GO:0046870)
0.2	24.1	GO:0030165	PDZ domain binding(GO:0030165)
0.0	21.3	GO:0043565	sequence-specific DNA binding(GO:0043565)
0.5	17.6	GO:0004364	glutathione transferase activity(GO:0004364)
0.3	16.6	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
2.0	16.0	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3	15.9	GO:0030507	spectrin binding(GO:0030507)
5.2	15.5	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.2	14.4	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2	13.6	GO:0005201	extracellular matrix structural constituent(GO:0005201)

Showing 1 to 10 of 105 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	21.8	PID AP1 PATHWAY	AP-1 transcription factor network
0.1	17.2	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.9	14.9	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.2	13.3	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.4	12.2	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.6	11.8	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.2	11.2	ST GA13 PATHWAY	G alpha 13 Pathway
0.2	9.2	PID ERBB4 PATHWAY	ErbB4 signaling events
0.2	7.1	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.5	5.9	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta

Showing 1 to 10 of 32 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.0	36.8	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.9	22.2	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.6	17.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.2	16.6	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.4	15.0	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
1.0	13.2	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.4	11.8	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	11.6	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.3	11.2	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.5	10.5	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling

Showing 1 to 10 of 45 entries

Results for Tfcp2

Z-value: 0.81

Motif logo

Transcription factors associated with Tfcp2

Activity-expression correlation:

Activity profile of Tfcp2 motif

Sorted Z-values of Tfcp2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfcp2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: