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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Tfcp2

Z-value: 0.81

Motif logo

Transcription factors associated with Tfcp2

Gene Symbol Gene ID Gene Info
ENSRNOG00000032395 transcription factor CP2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tfcp2rn6_v1_chr7_-_142180794_1421807940.556.7e-27Click!

Activity profile of Tfcp2 motif

Sorted Z-values of Tfcp2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_133896141 28.67 ENSRNOT00000011434
PDZK1 interacting protein 1
chr19_-_11308740 22.80 ENSRNOT00000067391
metallothionein 2A
chr2_-_225107283 21.24 ENSRNOT00000055711
solute carrier family 44, member 3
chr9_+_27402381 17.59 ENSRNOT00000077372
glutathione S-transferase alpha 3
chr7_-_145154131 15.99 ENSRNOT00000055271
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr20_+_20236151 15.02 ENSRNOT00000079630
ankyrin 3
chr5_-_33892462 14.80 ENSRNOT00000009334
ATPase H+ transporting V0 subunit D2
chr16_-_21348391 13.65 ENSRNOT00000083537
lysophosphatidic acid receptor 2
chr5_+_149077412 13.59 ENSRNOT00000014666
matrilin 1, cartilage matrix protein
chr4_-_148845267 13.57 ENSRNOT00000037397
transmembrane protein 72
chr15_+_38341089 13.22 ENSRNOT00000015367
fibroblast growth factor 9
chr10_+_3338808 12.59 ENSRNOT00000004384
ENSRNOT00000093444
MPV17 mitochondrial inner membrane protein like
chr9_-_75528644 11.79 ENSRNOT00000019283
erb-b2 receptor tyrosine kinase 4
chr20_+_48335540 11.77 ENSRNOT00000000352
CD24 molecule
chr8_+_13796021 11.75 ENSRNOT00000013927
V-set and transmembrane domain containing 5
chr10_+_56228043 11.28 ENSRNOT00000015769
spermidine/spermine N1-acetyltransferase family member 2
chr20_-_19637958 10.51 ENSRNOT00000074657
solute carrier family 16 (monocarboxylic acid transporters), member 9
chr3_+_56802714 10.27 ENSRNOT00000077551
glutamate-rich 2
chr7_+_144623555 10.25 ENSRNOT00000022217
homeo box C6
chr5_-_158439078 9.93 ENSRNOT00000025517
kelch domain containing 7A
chr2_+_179952227 9.66 ENSRNOT00000015081
platelet derived growth factor C
chr17_-_43504604 9.47 ENSRNOT00000083829
ENSRNOT00000066313
solute carrier family 17 member 1
chr7_-_126461658 9.36 ENSRNOT00000081032
wingless-type MMTV integration site family, member 7B
chr16_-_21338771 9.32 ENSRNOT00000014265
PBX homeobox 4
chr20_-_33323367 8.68 ENSRNOT00000080444
ROS proto-oncogene 1 , receptor tyrosine kinase
chr4_-_82177420 8.56 ENSRNOT00000074452
homeobox protein Hox-A6-like
chr6_+_50528823 8.43 ENSRNOT00000008321
laminin subunit beta 1
chr1_+_105285419 8.43 ENSRNOT00000089693
solute carrier family 6 member 5
chr4_+_163267450 8.24 ENSRNOT00000079337
transmembrane protein 52B
chr4_-_82263117 8.17 ENSRNOT00000008542
homeobox protein Hox-A6-like
chr17_+_30617382 8.06 ENSRNOT00000048923
enoyl-CoA delta isomerase 2
chrX_-_157172068 8.02 ENSRNOT00000087962
dual specificity phosphatase 9
chr20_-_44220702 7.97 ENSRNOT00000036853
family with sequence similarity 229, member B
chr17_-_69404323 7.92 ENSRNOT00000051342
ENSRNOT00000066282
aldo-keto reductase family 1, member C2
chr20_-_33322966 7.88 ENSRNOT00000000459
ROS proto-oncogene 1 , receptor tyrosine kinase
chr3_-_64095120 7.64 ENSRNOT00000016837
SEC14 and spectrin domain containing 1
chr2_+_185393441 7.14 ENSRNOT00000015802
SH3 domain containing 19
chr1_+_105284753 7.12 ENSRNOT00000041950
solute carrier family 6 member 5
chr17_-_32158538 7.04 ENSRNOT00000024141
NAD(P)H quinone dehydrogenase 2
chr19_-_601469 7.03 ENSRNOT00000016462
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr2_+_60169517 7.01 ENSRNOT00000080974
prolactin receptor
chr14_-_20920286 6.76 ENSRNOT00000004391
solute carrier family 4 member 4
chr4_-_16669368 6.74 ENSRNOT00000007608
piccolo (presynaptic cytomatrix protein)
chr10_-_36716601 6.52 ENSRNOT00000038838
similar to hypothetical protein 4930503F14
chr8_+_117268337 6.41 ENSRNOT00000072098
ENSRNOT00000083578
laminin subunit beta 2
chr4_+_66090681 6.30 ENSRNOT00000078066
tetratricopeptide repeat domain 26
chr4_-_117126822 6.23 ENSRNOT00000086720
RAB11 family interacting protein 5
chr2_+_186980992 6.14 ENSRNOT00000020717
Rho guanine nucleotide exchange factor 11
chr3_-_149905944 5.91 ENSRNOT00000021715
syntrophin, alpha 1
chr7_-_125795980 5.90 ENSRNOT00000017420
Rho GTPase activating protein 8
chr6_+_34028936 5.71 ENSRNOT00000085797
lysosomal protein transmembrane 4 alpha
chrX_+_110789269 5.70 ENSRNOT00000086014
ring finger protein 128, E3 ubiquitin protein ligase
chr7_+_130296897 5.61 ENSRNOT00000044854
adrenomedullin 2
chr14_+_9226125 5.58 ENSRNOT00000088047
WD repeat and FYVE domain containing 3
chr20_-_4879779 5.56 ENSRNOT00000081924
heat shock protein family A (Hsp70) member 1B
chr11_+_33812662 5.37 ENSRNOT00000085961
carbonyl reductase [NADPH] 1-like
chr7_-_142062870 5.29 ENSRNOT00000026531
solute carrier family 11 member 2
chr11_+_33812989 5.21 ENSRNOT00000042283
ENSRNOT00000075985
carbonyl reductase 1
chr11_-_36479868 5.14 ENSRNOT00000075762
non-histone chromosomal protein HMG-14-like
chr2_-_88135410 5.12 ENSRNOT00000014180
carbonic anhydrase 3
chr15_+_32894938 5.11 ENSRNOT00000012837
abhydrolase domain containing 4
chr2_+_186980793 5.10 ENSRNOT00000091336
Rho guanine nucleotide exchange factor 11
chr1_+_166433109 5.08 ENSRNOT00000026428
StAR-related lipid transfer domain containing 10
chr9_+_61655963 4.95 ENSRNOT00000040461
coenzyme Q10B
chr2_+_187697523 4.86 ENSRNOT00000026153
glycosylated lysosomal membrane protein
chr7_+_126028350 4.84 ENSRNOT00000042412
RIB43A domain with coiled-coils 2
chr8_-_116993193 4.78 ENSRNOT00000026327
dystroglycan 1
chr1_+_199196059 4.73 ENSRNOT00000090428
F-box and leucine-rich repeat protein 19
chr2_+_45668969 4.70 ENSRNOT00000014761
ENSRNOT00000071353
ADP-ribosylation factor like GTPase 15
chr10_+_63677396 4.67 ENSRNOT00000005100
solute carrier family 43 member 2
chr2_+_225570721 4.56 ENSRNOT00000017076
Rho GTPase activating protein 29
chr20_+_5050327 4.54 ENSRNOT00000083353
dimethylarginine dimethylaminohydrolase 2
chr1_+_214009784 4.52 ENSRNOT00000026079
CD151 antigen-like
chr18_+_30885789 4.44 ENSRNOT00000044434
protocadherin gamma subfamily A, 9
chr1_+_214446659 4.39 ENSRNOT00000072434
CD151 molecule (Raph blood group)
chr20_+_5049496 4.39 ENSRNOT00000088251
ENSRNOT00000001118
dimethylarginine dimethylaminohydrolase 2
chr5_+_4982348 4.36 ENSRNOT00000010369
lactamase, beta 2
chr1_+_214009986 4.27 ENSRNOT00000089241
CD151 antigen-like
chr4_-_82263302 4.25 ENSRNOT00000082933
homeobox protein Hox-A6-like
chr6_-_8344574 4.21 ENSRNOT00000009660
prolyl endopeptidase-like
chr9_+_65110330 4.12 ENSRNOT00000033068
ENSRNOT00000092868
aldehyde oxidase 4
chr10_+_92018562 4.07 ENSRNOT00000006483
ADP-ribosylation factor 2
chrX_-_104932508 4.05 ENSRNOT00000075325
NADPH oxidase 1
chr19_+_52217984 4.04 ENSRNOT00000079580
dynein, axonemal, assembly factor 1
chrX_-_72133692 4.00 ENSRNOT00000004263
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chr4_-_73174179 3.98 ENSRNOT00000048203
thiamin pyrophosphokinase 1
chr1_-_81127059 3.95 ENSRNOT00000026252
zinc finger protein 94
chr11_+_39482408 3.91 ENSRNOT00000075126
high mobility group nucleosome binding domain 1
chr7_+_97760134 3.83 ENSRNOT00000086792
TBC1 domain family, member 31
chr7_-_126028279 3.73 ENSRNOT00000044883
structural maintenance of chromosomes 1B
chr6_-_102047758 3.73 ENSRNOT00000012101
ATPase H+ transporting V1 subunit D
chr19_-_41161765 3.69 ENSRNOT00000023117
Hydin, axonemal central pair apparatus protein
chrX_+_118742313 3.68 ENSRNOT00000045110

chr1_-_250951697 3.67 ENSRNOT00000054761
sphingomyelin synthase 1
chr1_-_220938814 3.66 ENSRNOT00000028081
ovo like transcriptional repressor 1
chr5_+_157434481 3.64 ENSRNOT00000088556
transmembrane and coiled-coil domains 4
chr3_-_45169118 3.63 ENSRNOT00000086371
coiled-coil domain containing 148
chr11_+_61531416 3.63 ENSRNOT00000093263
ATPase H+ transporting V1 subunit A
chr2_-_195678848 3.62 ENSRNOT00000028303
ENSRNOT00000075569
ornithine decarboxylase antizyme 3
chr2_-_210473761 3.59 ENSRNOT00000066501
adenosylhomocysteinase-like 1
chr13_-_67206688 3.50 ENSRNOT00000003630
ENSRNOT00000090693
phospholipase A2 group IVA
chr10_+_37594578 3.48 ENSRNOT00000007676
S-phase kinase-associated protein 1
chr18_+_29960072 3.46 ENSRNOT00000071366

chr2_-_144467912 3.38 ENSRNOT00000040002
cyclin A1
chr11_-_31103520 3.38 ENSRNOT00000030279
similar to RIKEN cDNA 1110004E09
chr4_+_168832910 3.34 ENSRNOT00000011134
G protein-coupled receptor, class C, group 5, member A
chr3_+_11554457 3.26 ENSRNOT00000073087
family with sequence similarity 102, member A
chr6_-_8344897 3.19 ENSRNOT00000082353
prolyl endopeptidase-like
chr5_-_79570073 3.13 ENSRNOT00000011845
tumor necrosis factor superfamily member 15
chr12_-_29958050 3.13 ENSRNOT00000058725
transmembrane protein 248
chr19_+_37330930 3.12 ENSRNOT00000022439
pleckstrin homology and RhoGEF domain containing G4
chr3_+_103747654 2.91 ENSRNOT00000006887
NOP10 ribonucleoprotein
chr16_+_27399467 2.91 ENSRNOT00000065642
tolloid-like 1
chr15_+_108453147 2.90 ENSRNOT00000018486
translocase of inner mitochondrial membrane 8A2
chr9_+_88110731 2.88 ENSRNOT00000088677
rhomboid domain containing 1
chr9_-_71445739 2.85 ENSRNOT00000019698
frizzled class receptor 5
chr7_+_3630950 2.75 ENSRNOT00000074535
pre-mRNA-splicing factor CWC22 homolog
chr1_-_280233755 2.72 ENSRNOT00000064463
shootin 1
chr5_-_50193571 2.71 ENSRNOT00000051243
cilia and flagella associated protein 206
chr10_+_105500290 2.70 ENSRNOT00000079080
ENSRNOT00000083593
sphingosine kinase 1
chr5_+_146933592 2.66 ENSRNOT00000007851
alpha 1,3-galactosyltransferase 2
chr6_+_43234526 2.65 ENSRNOT00000086808
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr1_+_91663736 2.62 ENSRNOT00000089587
ENSRNOT00000031236
centrosomal protein 89
chr1_+_98627372 2.60 ENSRNOT00000030370
zinc finger protein 17
chrX_+_123404518 2.60 ENSRNOT00000015085
solute carrier family 25 member 5
chr1_-_188097374 2.56 ENSRNOT00000092246
synaptotagmin 17
chr1_-_71710374 2.53 ENSRNOT00000078556
ENSRNOT00000046152
NLR family, pyrin domain containing 4
chrX_-_143558521 2.51 ENSRNOT00000056598
hypothetical protein LOC688842
chr8_+_21611319 2.48 ENSRNOT00000068461
zinc finger protein 846
chr4_-_98735346 2.45 ENSRNOT00000008473
testis expressed 37
chr1_+_162419262 2.42 ENSRNOT00000016654
potassium channel tetramerization domain containing 14
chr3_-_162872831 2.38 ENSRNOT00000008478
sulfatase 2
chr1_+_264796812 2.37 ENSRNOT00000021171
sideroflexin 3
chr8_+_55279373 2.37 ENSRNOT00000064290
protein phosphatase 2 scaffold subunit A beta
chr9_-_23352668 2.34 ENSRNOT00000075279
methylmalonyl CoA mutase
chr7_-_70498992 2.29 ENSRNOT00000067774
ENSRNOT00000079327
phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
chr4_-_181477281 2.22 ENSRNOT00000055463
MANSC domain containing 4
chr7_-_140417530 2.19 ENSRNOT00000077884
FK506 binding protein 11
chr3_+_75906945 2.18 ENSRNOT00000047110
olfactory receptor 586
chr19_+_46761570 2.16 ENSRNOT00000058779
WW domain-containing oxidoreductase
chr3_-_57104030 2.14 ENSRNOT00000064203
tousled-like kinase 1
chr15_+_39779648 2.14 ENSRNOT00000084505
calcium binding protein 39-like
chr4_-_115453659 2.14 ENSRNOT00000065847
testis expressed 261
chr2_-_165600748 2.10 ENSRNOT00000013216
intraflagellar transport 80
chrX_+_145357553 2.10 ENSRNOT00000033723
MAGE family member C2
chr4_+_45567573 2.05 ENSRNOT00000089824
ankyrin repeat domain 7
chr3_-_123206828 2.02 ENSRNOT00000030192
DDRGK domain containing 1
chr10_+_3218466 2.02 ENSRNOT00000093629
ENSRNOT00000093338
ENSRNOT00000077695
N-terminal asparagine amidase
chr7_-_69982592 1.99 ENSRNOT00000040010
similar to developmental pluripotency associated 5
chr1_+_201117630 1.97 ENSRNOT00000077908
transforming, acidic coiled-coil containing protein 2
chr19_+_55880561 1.92 ENSRNOT00000047754
ENSRNOT00000091712
SPG7, paraplegin matrix AAA peptidase subunit
chr13_-_47154292 1.90 ENSRNOT00000005284
CD55 molecule, decay accelerating factor for complement
chr10_+_109533487 1.89 ENSRNOT00000054975
fascin actin-bundling protein 2, retinal
chr18_+_30435119 1.89 ENSRNOT00000027190
protocadherin beta 8
chr17_-_45154355 1.89 ENSRNOT00000084976
zinc finger with KRAB and SCAN domains 4
chr1_-_276228574 1.89 ENSRNOT00000021746
guanylate cyclase 2G
chr3_-_78066123 1.88 ENSRNOT00000073165
olfactory receptor 690
chr1_+_101152734 1.87 ENSRNOT00000028022
PIH1 domain containing 1
chr1_-_242440885 1.87 ENSRNOT00000076537
phosphatidylinositol-4-phosphate 5-kinase type 1 beta
chr1_+_168489077 1.85 ENSRNOT00000021191
olfactory receptor 96
chr4_+_113782206 1.84 ENSRNOT00000009701
meiosis 1 associated protein
chr2_-_148722263 1.81 ENSRNOT00000017868
stress-associated endoplasmic reticulum protein 1
chr7_-_142063212 1.80 ENSRNOT00000089912
solute carrier family 11 member 2
chrX_+_112311251 1.79 ENSRNOT00000086698

chrX_-_135342996 1.79 ENSRNOT00000084848
ENSRNOT00000008503
apoptosis inducing factor, mitochondria associated 1
chr4_-_51003117 1.76 ENSRNOT00000034936
taste receptor, type 2, member 118
chr3_-_91839009 1.75 ENSRNOT00000083703
low density lipoprotein receptor class A domain containing 3
chr5_+_155794229 1.75 ENSRNOT00000018127
hypothetical protein LOC690206
chr1_-_242441247 1.75 ENSRNOT00000068645
phosphatidylinositol-4-phosphate 5-kinase type 1 beta
chr18_+_30387937 1.73 ENSRNOT00000027210
protocadherin beta 4
chr1_+_69866069 1.72 ENSRNOT00000083609
zinc finger protein 419-like
chr14_-_84751886 1.72 ENSRNOT00000078838
myotubularin related protein 3
chr12_+_12859661 1.67 ENSRNOT00000001404
ubiquitin specific peptidase 42
chr16_-_70998575 1.59 ENSRNOT00000019935
potassium calcium-activated channel subfamily U member 1
chr8_-_50277797 1.57 ENSRNOT00000082508
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2
chr1_-_212021567 1.57 ENSRNOT00000029027
cilia and flagella associated protein 46
chr12_+_2170630 1.56 ENSRNOT00000071928
PET100 homolog
chr4_+_88048267 1.52 ENSRNOT00000044913
vomeronasal 1 receptor 81
chr1_-_91663467 1.52 ENSRNOT00000033396
Fanconi anemia core complex associated protein 24
chr5_+_159612762 1.52 ENSRNOT00000012147
spermatogenesis associated 21
chr1_+_101427195 1.49 ENSRNOT00000028271
glycogen synthase 1
chr5_+_155660553 1.46 ENSRNOT00000081893
wingless-type MMTV integration site family, member 4
chr1_+_169115981 1.45 ENSRNOT00000067478
olfactory receptor 135
chr6_-_10592454 1.36 ENSRNOT00000020600
phosphatidylinositol glycan anchor biosynthesis, class F
chr7_+_70335061 1.36 ENSRNOT00000072176
ENSRNOT00000084933
cytochrome P450, family 27, subfamily b, polypeptide 1
chr1_-_263845762 1.35 ENSRNOT00000017268
ER lipid raft associated 1
chr15_-_9086282 1.34 ENSRNOT00000008989
thyroid hormone receptor beta
chr3_+_11587941 1.32 ENSRNOT00000071505
dolichyl-phosphate mannosyltransferase subunit 2, regulatory
chr13_-_99531959 1.32 ENSRNOT00000005059
WD repeat domain 26
chr1_+_217039755 1.30 ENSRNOT00000091603
actin-like
chr7_-_9465527 1.29 ENSRNOT00000044882
olfactory receptor 1069
chr6_-_24201864 1.27 ENSRNOT00000080972

chr18_+_30880020 1.25 ENSRNOT00000060468
protocadherin gamma subfamily B, 5
chr7_-_59139910 1.22 ENSRNOT00000032374
RIKEN cDNA 4933416C03 gene
chr10_-_13892997 1.20 ENSRNOT00000004192
TNF receptor associated factor 7
chr4_-_146839397 1.19 ENSRNOT00000010338
vestigial-like family member 4
chr4_+_87353254 1.15 ENSRNOT00000073670
vomeronasal 1 receptor 67
chr1_-_103426467 1.08 ENSRNOT00000045792
MAS-related GPR, member B4
chr10_+_104582955 1.07 ENSRNOT00000009733
unkempt family zinc finger
chr3_+_76468294 1.04 ENSRNOT00000037779
olfactory receptor 619

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfcp2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 17.6 GO:0046223 toxin catabolic process(GO:0009407) mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) secondary metabolite catabolic process(GO:0090487) organic heteropentacyclic compound catabolic process(GO:1901377)
3.9 11.8 GO:0002840 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
3.8 15.0 GO:1900827 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
3.3 22.8 GO:0048143 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016) astrocyte activation(GO:0048143)
3.1 9.4 GO:0072054 renal outer medulla development(GO:0072054)
3.1 15.5 GO:0036233 glycine import(GO:0036233)
2.8 11.3 GO:0032919 spermine acetylation(GO:0032919)
2.8 8.4 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
2.8 16.6 GO:0010966 regulation of phosphate transport(GO:0010966)
2.6 7.9 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
2.6 10.3 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
2.4 7.1 GO:0015692 nickel cation transport(GO:0015675) vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) nickel cation transmembrane transport(GO:0035444)
1.9 13.6 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
1.9 5.6 GO:0031439 positive regulation of mRNA cleavage(GO:0031439) positive regulation of endoribonuclease activity(GO:1902380) positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904722)
1.7 11.8 GO:0007262 STAT protein import into nucleus(GO:0007262)
1.6 6.4 GO:0072249 metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
1.4 7.0 GO:0009758 carbohydrate utilization(GO:0009758)
1.3 4.0 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
1.3 13.2 GO:0060484 lung-associated mesenchyme development(GO:0060484)
1.3 3.9 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
1.3 5.2 GO:1901662 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
1.3 16.7 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
1.3 7.6 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
1.2 3.6 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
1.1 6.7 GO:0098928 synaptic vesicle targeting(GO:0016080) presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
1.1 5.6 GO:0035973 aggrephagy(GO:0035973)
1.1 20.0 GO:0046415 urate metabolic process(GO:0046415)
1.0 6.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
1.0 4.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726) oxygen metabolic process(GO:0072592)
1.0 4.0 GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
1.0 2.9 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
1.0 2.9 GO:0060061 Spemann organizer formation(GO:0060061)
0.9 1.9 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.9 3.7 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.9 2.7 GO:0042125 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.8 4.1 GO:0009115 xanthine catabolic process(GO:0009115)
0.8 2.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.7 5.1 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.7 8.9 GO:0006527 arginine catabolic process(GO:0006527)
0.7 2.7 GO:0070650 actin filament bundle distribution(GO:0070650)
0.7 1.4 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) vitamin D catabolic process(GO:0042369)
0.7 2.0 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.7 6.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.6 3.7 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.6 3.5 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.6 4.0 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.6 18.4 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.5 2.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.5 3.7 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.5 3.6 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.5 1.5 GO:0060748 female sex determination(GO:0030237) tertiary branching involved in mammary gland duct morphogenesis(GO:0060748) positive regulation of dermatome development(GO:0061184) regulation of testosterone biosynthetic process(GO:2000224)
0.5 1.9 GO:2000563 regulation of complement activation, classical pathway(GO:0030450) positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.5 2.4 GO:0006842 tricarboxylic acid transport(GO:0006842)
0.5 1.4 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.4 4.8 GO:0071679 cytoskeletal anchoring at plasma membrane(GO:0007016) commissural neuron axon guidance(GO:0071679)
0.4 13.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.4 7.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.4 7.0 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.4 1.8 GO:1904045 cellular response to aldosterone(GO:1904045)
0.3 2.6 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.3 5.0 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.3 0.6 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.3 3.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.3 0.9 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.3 1.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.3 1.8 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.3 2.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.3 0.8 GO:0010034 response to acetate(GO:0010034)
0.3 0.8 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.2 4.5 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.2 3.5 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.2 0.7 GO:0021508 floor plate formation(GO:0021508)
0.2 17.5 GO:0044042 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.2 5.7 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.2 6.8 GO:0015701 bicarbonate transport(GO:0015701)
0.2 0.6 GO:0009177 pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177) dUMP metabolic process(GO:0046078)
0.2 2.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.2 2.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.2 0.8 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.2 1.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.2 2.3 GO:0050667 homocysteine metabolic process(GO:0050667)
0.2 5.1 GO:0006730 one-carbon metabolic process(GO:0006730)
0.2 0.8 GO:2000327 positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.2 0.6 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.2 0.6 GO:0061107 seminal vesicle development(GO:0061107)
0.2 5.9 GO:0042073 intraciliary transport(GO:0042073)
0.1 0.7 GO:0034627 'de novo' NAD biosynthetic process(GO:0034627)
0.1 2.0 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 8.1 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 1.8 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 1.6 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.1 14.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 3.7 GO:0061512 protein localization to cilium(GO:0061512)
0.1 4.4 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 1.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.5 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 3.6 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 0.6 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 5.2 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.1 1.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.1 0.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.3 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 1.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 8.7 GO:0048706 embryonic skeletal system development(GO:0048706)
0.1 1.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 1.8 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 1.9 GO:0008089 anterograde axonal transport(GO:0008089)
0.1 1.9 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 2.7 GO:0035082 axoneme assembly(GO:0035082)
0.1 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.9 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.1 0.3 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 1.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.5 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 2.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 3.1 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 2.9 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 1.6 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.0 1.6 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.5 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.1 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.0 0.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.7 GO:0070613 regulation of protein processing(GO:0070613)
0.0 3.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 5.4 GO:0030522 intracellular receptor signaling pathway(GO:0030522)
0.0 0.8 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.1 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.1 GO:0070826 paraferritin complex(GO:0070826)
2.2 6.7 GO:0044317 rod spherule(GO:0044317)
2.1 8.4 GO:0043259 laminin-1 complex(GO:0005606) laminin-2 complex(GO:0005607) laminin-10 complex(GO:0043259)
1.5 15.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
1.4 5.6 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
1.3 6.4 GO:0005608 laminin-3 complex(GO:0005608)
1.1 14.8 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.7 3.7 GO:1990716 axonemal central apparatus(GO:1990716)
0.7 4.8 GO:0016011 dystroglycan complex(GO:0016011)
0.7 11.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.6 1.9 GO:0005745 m-AAA complex(GO:0005745)
0.6 3.5 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.6 4.1 GO:0071438 invadopodium membrane(GO:0071438)
0.5 3.7 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.5 9.3 GO:0001741 XY body(GO:0001741)
0.5 7.4 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.5 2.7 GO:0005879 axonemal microtubule(GO:0005879)
0.4 5.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.4 1.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.4 2.6 GO:0071817 MMXD complex(GO:0071817)
0.4 5.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.4 3.7 GO:0000138 Golgi trans cisterna(GO:0000138)
0.4 8.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.4 2.9 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.3 8.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.3 1.9 GO:0070761 pre-snoRNP complex(GO:0070761)
0.2 3.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 2.6 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 17.7 GO:0005604 basement membrane(GO:0005604)
0.2 0.8 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 9.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.6 GO:0031094 platelet dense tubular network(GO:0031094)
0.1 0.7 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 3.5 GO:0042588 zymogen granule(GO:0042588)
0.1 7.6 GO:0034704 calcium channel complex(GO:0034704)
0.1 11.8 GO:0005901 caveola(GO:0005901)
0.1 0.7 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 5.9 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 4.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 13.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 5.2 GO:1903293 phosphatase complex(GO:1903293)
0.1 0.6 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 1.0 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 2.7 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.8 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 3.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 5.7 GO:0005902 microvillus(GO:0005902)
0.1 1.6 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 16.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 0.5 GO:0005869 dynactin complex(GO:0005869)
0.1 9.5 GO:0030139 endocytic vesicle(GO:0030139)
0.1 0.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.9 GO:0032420 stereocilium(GO:0032420)
0.1 2.1 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 4.0 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 5.3 GO:0005770 late endosome(GO:0005770)
0.0 5.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 2.3 GO:0005776 autophagosome(GO:0005776)
0.0 3.5 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 24.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 5.5 GO:0016324 apical plasma membrane(GO:0016324)
0.0 36.3 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.6 GO:0010369 chromocenter(GO:0010369)
0.0 3.3 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 2.7 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.1 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.6 GO:0015030 Cajal body(GO:0015030)
0.0 4.3 GO:0031966 mitochondrial membrane(GO:0031966)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 15.5 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
3.1 9.4 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
3.0 8.9 GO:0016403 dimethylargininase activity(GO:0016403)
2.7 29.9 GO:0046870 cadmium ion binding(GO:0046870)
2.6 5.1 GO:0016151 nickel cation binding(GO:0016151)
2.3 7.0 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
2.3 7.0 GO:0004925 prolactin receptor activity(GO:0004925)
2.3 11.3 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
2.0 8.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
2.0 16.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
2.0 7.9 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
1.9 5.6 GO:0031249 denatured protein binding(GO:0031249)
1.4 5.6 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
1.3 11.8 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
1.2 3.6 GO:0015203 ornithine decarboxylase inhibitor activity(GO:0008073) polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
1.0 5.2 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
1.0 7.0 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.9 8.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.9 2.7 GO:0008481 sphinganine kinase activity(GO:0008481)
0.9 3.6 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.8 5.0 GO:0048039 ubiquinone binding(GO:0048039)
0.8 4.1 GO:0016726 aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.8 4.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.8 9.5 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.8 2.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.7 3.7 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.7 2.7 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.6 7.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.6 3.6 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.6 4.8 GO:0043237 laminin-1 binding(GO:0043237)
0.6 2.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.6 11.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.5 7.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.5 2.4 GO:0015142 tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.5 17.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.4 4.0 GO:0016778 diphosphotransferase activity(GO:0016778)
0.4 1.3 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.4 9.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.4 13.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.4 4.0 GO:0050693 LBD domain binding(GO:0050693)
0.4 1.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.4 1.6 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.4 3.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.4 6.7 GO:0005522 profilin binding(GO:0005522)
0.3 1.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.3 6.8 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.3 15.9 GO:0030507 spectrin binding(GO:0030507)
0.3 2.3 GO:0031419 cobalamin binding(GO:0031419)
0.3 2.6 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.3 7.1 GO:0070064 proline-rich region binding(GO:0070064)
0.3 16.6 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.3 0.8 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 1.9 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.2 13.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 1.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.2 0.6 GO:0004995 tachykinin receptor activity(GO:0004995)
0.2 3.5 GO:0097602 cullin family protein binding(GO:0097602)
0.2 1.8 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 6.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 1.1 GO:1990715 mRNA CDS binding(GO:1990715)
0.2 4.5 GO:0070840 dynein complex binding(GO:0070840)
0.2 3.1 GO:0005123 death receptor binding(GO:0005123)
0.2 3.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.2 2.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 24.1 GO:0030165 PDZ domain binding(GO:0030165)
0.2 14.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 0.6 GO:0032190 acrosin binding(GO:0032190)
0.1 1.8 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 1.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 4.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 11.3 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 3.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.9 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.6 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.5 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 3.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 1.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 5.7 GO:0005178 integrin binding(GO:0005178)
0.1 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.1 2.7 GO:0019894 kinesin binding(GO:0019894)
0.0 2.9 GO:0005518 collagen binding(GO:0005518)
0.0 2.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 2.2 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 1.5 GO:0005109 frizzled binding(GO:0005109)
0.0 1.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 2.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 3.7 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 1.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 8.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.6 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 1.4 GO:0015485 cholesterol binding(GO:0015485)
0.0 2.0 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 21.3 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 3.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.2 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 2.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 14.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.7 4.8 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.6 11.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.5 5.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.4 12.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.3 3.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3 21.8 PID AP1 PATHWAY AP-1 transcription factor network
0.2 9.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.2 11.2 ST GA13 PATHWAY G alpha 13 Pathway
0.2 13.3 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.2 3.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.2 2.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.2 7.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 5.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 3.7 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 3.5 PID ENDOTHELIN PATHWAY Endothelins
0.1 0.8 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 1.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 2.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 17.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 1.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 1.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 3.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 3.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 5.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.4 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 13.2 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
1.0 36.8 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.9 22.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.8 9.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.6 17.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.5 3.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.5 10.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.5 7.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.4 11.8 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.4 15.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 6.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.3 11.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 16.6 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.2 3.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.2 3.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 2.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 6.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 2.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 7.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 5.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 2.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 2.1 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 1.4 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 11.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 5.6 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 2.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 10.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 2.6 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 4.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 3.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 3.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 6.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 0.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 2.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.5 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 1.9 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.9 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events