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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Tfap2b

Z-value: 0.75

Motif logo

Transcription factors associated with Tfap2b

Gene Symbol Gene ID Gene Info
ENSRNOG00000011823 transcription factor AP-2 beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tfap2brn6_v1_chr9_+_25410669_25410717-0.106.7e-02Click!

Activity profile of Tfap2b motif

Sorted Z-values of Tfap2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_197858016 32.99 ENSRNOT00000074778
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr2_+_189629297 24.24 ENSRNOT00000049810
DENN domain containing 4B
chr7_-_116781766 23.01 ENSRNOT00000010084
MAF bZIP transcription factor A
chr17_+_70684539 15.39 ENSRNOT00000025700
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr7_+_144577465 15.17 ENSRNOT00000021647
homeo box C10
chr17_+_70684134 15.05 ENSRNOT00000025731
ENSRNOT00000068354
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr17_+_70684340 14.87 ENSRNOT00000051067
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr2_-_238068694 12.69 ENSRNOT00000079479
ENSRNOT00000078608
ENSRNOT00000090834
nephronectin
chr1_+_82480195 12.64 ENSRNOT00000028051
transforming growth factor, beta 1
chr1_+_87045796 12.43 ENSRNOT00000027620
galectin 7
chr4_-_157252104 12.35 ENSRNOT00000082739
protein tyrosine phosphatase, non-receptor type 6
chr10_+_4957326 12.22 ENSRNOT00000003458
suppressor of cytokine signaling 1
chr10_+_86340940 11.37 ENSRNOT00000073486
phenylethanolamine-N-methyltransferase
chr6_-_99783047 10.93 ENSRNOT00000009028
spectrin, beta, erythrocytic
chr5_-_157199441 10.40 ENSRNOT00000022559
phospholipase A2, group IIF
chr1_+_273563441 10.36 ENSRNOT00000048691
similar to 60S ribosomal protein L8
chr1_-_142183884 10.06 ENSRNOT00000016032
FES proto-oncogene, tyrosine kinase
chr20_+_4355175 10.06 ENSRNOT00000000510
G-protein signaling modulator 3
chr19_+_37568113 9.79 ENSRNOT00000023710
family with sequence similarity 65, member A
chr10_+_84167331 9.67 ENSRNOT00000010965
homeo box B4
chr6_+_10533151 9.66 ENSRNOT00000020822
ras homolog family member Q
chr14_+_86101277 9.64 ENSRNOT00000018846
AE binding protein 1
chr6_+_93281408 9.35 ENSRNOT00000009610
FERM domain containing 6
chr1_-_264975132 9.31 ENSRNOT00000021748
ladybird homeobox 1
chr3_-_57913999 9.22 ENSRNOT00000090426
solute carrier family 25 member 12
chr1_-_59347472 9.20 ENSRNOT00000017718
leucyl and cystinyl aminopeptidase
chr7_-_77162148 9.20 ENSRNOT00000008350
Kruppel-like factor 10
chr19_-_55490426 9.06 ENSRNOT00000081800
CBFA2/RUNX1 translocation partner 3
chr7_-_140546908 8.96 ENSRNOT00000077502
lysine methyltransferase 2D
chr8_-_72841496 8.70 ENSRNOT00000057641
ENSRNOT00000040808
ENSRNOT00000085894
ENSRNOT00000024575
ENSRNOT00000048044
ENSRNOT00000024493
tropomyosin 1, alpha
chr19_-_59502161 8.43 ENSRNOT00000075292
interferon regulatory factor 2 binding protein 2
chr1_+_68436917 8.33 ENSRNOT00000088586
leucyl-cystinyl aminopeptidase
chr1_+_68436593 8.00 ENSRNOT00000080325
leucyl-cystinyl aminopeptidase
chr3_-_162581610 7.83 ENSRNOT00000079324
zinc finger, MYND-type containing 8
chr7_-_14303055 7.82 ENSRNOT00000008963
bromodomain containing 4
chr11_+_85992696 7.78 ENSRNOT00000084433

chr20_+_3990820 7.69 ENSRNOT00000000528
proteasome subunit beta 8
chr2_+_189169877 7.58 ENSRNOT00000028225
Src homology 2 domain containing E
chr3_+_3389612 7.30 ENSRNOT00000041984
ribosomal protein L8
chr3_-_80933283 7.29 ENSRNOT00000007771
cAMP responsive element binding protein 3-like 1
chr9_+_17086475 7.24 ENSRNOT00000025660
tight junction associated protein 1
chr3_-_172537877 7.03 ENSRNOT00000072069
cathepsin Z
chr5_-_152198813 7.03 ENSRNOT00000082953
high mobility group nucleosomal binding domain 2
chr11_+_82466071 6.99 ENSRNOT00000036958
insulin-like growth factor 2 mRNA binding protein 2
chr9_-_20621051 6.98 ENSRNOT00000015918
TNF receptor superfamily member 21
chrX_-_38196060 6.86 ENSRNOT00000006741
ENSRNOT00000006438
SH3 domain-containing kinase-binding protein 1
chr1_+_213991620 6.83 ENSRNOT00000038691
ribosomal protein lateral stalk subunit P2
chr1_-_48891130 6.75 ENSRNOT00000083884

chr10_-_56864005 6.74 ENSRNOT00000033098
ENSRNOT00000091131
arachidonate 12-lipoxygenase, 12S type
chr4_-_115354795 6.73 ENSRNOT00000017691
CD207 molecule
chr10_+_39109522 6.61 ENSRNOT00000010968
interferon regulatory factor 1
chr20_+_3827367 6.51 ENSRNOT00000079967
retinoid X receptor beta
chr12_+_49761120 6.49 ENSRNOT00000070961
myosin XVIIIb
chr7_-_63578490 6.47 ENSRNOT00000007295
Ras association domain family member 3
chrX_-_114232939 6.45 ENSRNOT00000042639
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr10_+_17421075 6.43 ENSRNOT00000047011
serine/threonine kinase 10
chr5_+_151436464 6.26 ENSRNOT00000012463
mitogen-activated protein kinase kinase kinase 6
chr13_+_51795867 6.23 ENSRNOT00000006747
ubiquitin-conjugating enzyme E2T
chr20_+_6973398 6.20 ENSRNOT00000041665
FYVE, RhoGEF and PH domain containing 2
chr9_+_93545396 5.96 ENSRNOT00000025093
hypothetical protein LOC100359583
chr1_+_87045335 5.92 ENSRNOT00000084393
galectin 7
chr19_+_52647070 5.77 ENSRNOT00000068389
ENSRNOT00000087857
cysteine-rich secretory protein LCCL domain containing 2
chr10_+_30833914 5.76 ENSRNOT00000035346
ENSRNOT00000079437
clathrin interactor 1
chr10_+_13145099 5.68 ENSRNOT00000091287
serine/arginine repetitive matrix 2
chr14_+_7618022 5.68 ENSRNOT00000088508
ENSRNOT00000002819
solute carrier family 10 member 6
chr7_-_11777503 5.60 ENSRNOT00000026220
anti-Mullerian hormone
chr1_+_101687855 5.59 ENSRNOT00000028546
ENSRNOT00000091597
D-box binding PAR bZIP transcription factor
chr9_+_54212767 5.56 ENSRNOT00000078073
ENSRNOT00000090026
glutaminase
chr10_-_62287189 5.54 ENSRNOT00000004365
WD repeat domain 81
chr17_-_90627101 5.50 ENSRNOT00000003349
nidogen 1
chr3_+_172385672 5.35 ENSRNOT00000090989
GNAS complex locus
chr1_+_153589471 5.31 ENSRNOT00000023205
frizzled class receptor 4
chr1_-_82580007 5.19 ENSRNOT00000078668
Axl receptor tyrosine kinase
chr3_+_155160481 5.18 ENSRNOT00000021133
protein phosphatase 1, regulatory subunit 16B
chr7_+_27221152 5.16 ENSRNOT00000031297
hypothetical protein LOC691921
chr20_-_31072469 5.15 ENSRNOT00000082448
eukaryotic translation initiation factor 4E binding protein 2
chr1_-_222242644 5.13 ENSRNOT00000050891
vascular endothelial growth factor B
chr1_-_219422268 5.06 ENSRNOT00000025092
carnosine synthase 1
chr19_-_55423052 5.05 ENSRNOT00000019528
ENSRNOT00000079641
galactosamine (N-acetyl)-6-sulfatase
chr5_-_155381732 5.04 ENSRNOT00000033670
zinc finger and BTB domain containing 40
chr13_+_48513008 4.97 ENSRNOT00000009742
solute carrier family 26 member 9
chr7_-_143552588 4.97 ENSRNOT00000086317
ENSRNOT00000092619
ENSRNOT00000092138
keratin 78
chr19_-_57614558 4.91 ENSRNOT00000025948
similar to RIKEN cDNA 0610039J04
chr5_+_63781801 4.89 ENSRNOT00000008302
nuclear receptor subfamily 4, group A, member 3
chr20_-_29511382 4.68 ENSRNOT00000085026
DNA-damage-inducible transcript 4
chr15_+_19690194 4.63 ENSRNOT00000010612
serine/threonine/tyrosine interacting protein
chrX_+_120859968 4.59 ENSRNOT00000085185
WD repeat domain 44
chr8_+_118821729 4.44 ENSRNOT00000028409
SET domain containing 2
chr5_+_59348639 4.35 ENSRNOT00000084031
ENSRNOT00000060264
reversion-inducing-cysteine-rich protein with kazal motifs
chr6_-_110904288 4.34 ENSRNOT00000014645
interferon regulatory factor 2 binding protein-like
chr4_+_7662019 4.33 ENSRNOT00000014023
family with sequence similarity 126, member A
chr10_-_85684138 4.32 ENSRNOT00000017989
phosphatidylinositol-5-phosphate 4-kinase type 2 beta
chr8_+_48805684 4.26 ENSRNOT00000064041
B-cell CLL/lymphoma 9-like
chr5_-_159293673 3.98 ENSRNOT00000009081
peptidyl arginine deiminase 4
chr1_+_177764445 3.94 ENSRNOT00000037185
Ras association domain family member 10
chr18_-_40518988 3.93 ENSRNOT00000004784
fem-1 homolog C
chr1_-_127599257 3.85 ENSRNOT00000018436
ankyrin repeat and SOCS box-containing 7
chr3_-_52998650 3.54 ENSRNOT00000009988
similar to 40S ribosomal protein S3
chr20_+_6049286 3.50 ENSRNOT00000042143
ENSRNOT00000092566
bromodomain and PHD finger containing, 3
chr16_+_55834458 3.47 ENSRNOT00000086141

chr13_-_49169918 3.45 ENSRNOT00000000036
transmembrane and coiled-coil domain family 2
chr4_+_157523770 3.44 ENSRNOT00000055985
ENSRNOT00000023240
zinc finger protein 384
chr10_-_73787083 3.42 ENSRNOT00000035280
mediator complex subunit 13
chr10_-_35800120 3.39 ENSRNOT00000004361
mastermind-like transcriptional coactivator 1
chr6_+_26566494 3.39 ENSRNOT00000079292
general transcription factor IIIC subunit 2
chr13_-_60496511 3.39 ENSRNOT00000004495
cell division cycle 73
chr19_+_37252843 3.33 ENSRNOT00000021145
E2F transcription factor 4
chr4_-_152835182 3.33 ENSRNOT00000036721
beta-1,4-N-acetyl-galactosaminyl transferase 3
chr9_+_46270122 2.97 ENSRNOT00000031352
CCR4-NOT transcription complex, subunit 11
chr8_+_128087345 2.96 ENSRNOT00000019777
activin A receptor type 2B
chr1_+_47942800 2.95 ENSRNOT00000079312
Wilms tumor 1 associated protein
chrX_+_14498283 2.94 ENSRNOT00000092143
X-linked Kx blood group
chr3_-_123702732 2.93 ENSRNOT00000028859
similar to RIKEN cDNA 1700037H04
chr5_+_140692779 2.90 ENSRNOT00000019101
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr15_+_44411865 2.81 ENSRNOT00000017566
potassium channel tetramerization domain containing 9
chr1_+_154377447 2.78 ENSRNOT00000084268
ENSRNOT00000092086
ENSRNOT00000091470
ENSRNOT00000025415
phosphatidylinositol binding clathrin assembly protein
chr19_+_57614628 2.75 ENSRNOT00000026617
glyceronephosphate O-acyltransferase
chr20_+_3823596 2.68 ENSRNOT00000087670
retinoid X receptor beta
chr12_-_37682964 2.59 ENSRNOT00000001421
similar to hypothetical protein FLJ38663
chr14_-_85398532 2.54 ENSRNOT00000057361
EMI domain containing 1
chr1_+_78933372 2.45 ENSRNOT00000029810
coiled-coil domain containing 8
chr2_-_243224883 2.38 ENSRNOT00000014139
dual adaptor of phosphotyrosine and 3-phosphoinositides 1
chr2_+_116028781 2.38 ENSRNOT00000089477
polyhomeotic homolog 3
chr16_-_61091169 2.37 ENSRNOT00000016328
dual specificity phosphatase 4
chr3_+_46286712 2.29 ENSRNOT00000085563
membrane associated ring-CH-type finger 7
chr1_+_47942500 2.22 ENSRNOT00000025936
Wilms tumor 1 associated protein
chr12_-_30501860 2.17 ENSRNOT00000001227
chaperonin containing TCP1 subunit 6A
chr17_-_14828329 2.15 ENSRNOT00000022830
BARX homeobox 1
chr5_+_150833819 2.12 ENSRNOT00000056170
EYA transcriptional coactivator and phosphatase 3
chr4_+_157647082 2.07 ENSRNOT00000024938
NOP2 nucleolar protein
chr17_-_35037076 2.01 ENSRNOT00000090946
dual specificity phosphatase 22
chr8_-_56696968 2.00 ENSRNOT00000016637
zinc finger CCCH type containing 12C
chr3_-_51297852 1.99 ENSRNOT00000001607
cordon-bleu WH2 repeat protein-like 1
chrX_+_68782872 1.94 ENSRNOT00000075995
StAR-related lipid transfer domain containing 8
chr7_+_141237768 1.91 ENSRNOT00000091717
aquaporin 2
chr10_+_110469290 1.90 ENSRNOT00000054919
forkhead box K2
chr19_+_46761570 1.81 ENSRNOT00000058779
WW domain-containing oxidoreductase
chr2_+_119197239 1.79 ENSRNOT00000048030
ubiquitin specific peptidase 13
chr10_+_84119884 1.68 ENSRNOT00000009951
homeo box B9
chr4_-_150616895 1.44 ENSRNOT00000073562
ankyrin repeat domain 26
chr8_-_37126809 1.41 ENSRNOT00000040783
prostate and testis expressed protein 2-like
chr15_-_34322115 1.38 ENSRNOT00000026734
transmembrane 9 superfamily member 1
chr7_+_130498199 1.29 ENSRNOT00000092684
ENSRNOT00000092431
SH3 and multiple ankyrin repeat domains 3
chr1_+_154377247 1.27 ENSRNOT00000092945
phosphatidylinositol binding clathrin assembly protein
chr3_-_3594475 1.20 ENSRNOT00000064861
RGD1564379
chr1_+_85324079 1.19 ENSRNOT00000093693
sterile alpha motif domain containing 4B
chr17_+_10676943 1.09 ENSRNOT00000000116
THO complex 3
chr12_+_19335841 1.07 ENSRNOT00000001831
metallo-beta-lactamase domain containing 1
chr14_-_85982794 1.05 ENSRNOT00000076874
upregulator of cell proliferation
chr6_+_136042059 1.03 ENSRNOT00000088784
microtubule affinity regulating kinase 3
chr7_-_141424225 1.02 ENSRNOT00000080109
ENSRNOT00000084292
ceramide synthase 5
chr1_-_142164007 1.01 ENSRNOT00000078982
mannosidase, alpha, class 2A, member 2
chr1_-_142164263 0.98 ENSRNOT00000016281
mannosidase, alpha, class 2A, member 2
chr15_-_28611946 0.96 ENSRNOT00000016288
SPT16 homolog, facilitates chromatin remodeling subunit
chr8_-_131899023 0.90 ENSRNOT00000034690
zinc finger protein 445
chr7_-_26984400 0.89 ENSRNOT00000013613
thioredoxin reductase 1
chr2_+_203200427 0.86 ENSRNOT00000020566
V-set domain containing T cell activation inhibitor 1
chr7_-_119185238 0.72 ENSRNOT00000007598
FAD-dependent oxidoreductase domain containing 2
chr1_+_221735517 0.70 ENSRNOT00000028628
ENSRNOT00000044866
splicing factor 1
chr3_+_126335863 0.68 ENSRNOT00000028904
bone morphogenetic protein 2
chr8_+_79606789 0.64 ENSRNOT00000087114
pygopus family PHD finger 1
chr8_+_62298358 0.63 ENSRNOT00000025525
cytochrome c oxidase subunit 5A
chr14_-_86297623 0.62 ENSRNOT00000067162
ENSRNOT00000081607
ENSRNOT00000085265
calcium/calmodulin-dependent protein kinase II beta
chr13_-_72869396 0.51 ENSRNOT00000093563
similar to 6820428L09 protein
chr11_-_83926524 0.48 ENSRNOT00000041777
ENSRNOT00000040029
eukaryotic translation initiation factor 4 gamma, 1
chr1_+_264504591 0.48 ENSRNOT00000050076
paired box 2
chr20_+_3556560 0.47 ENSRNOT00000085635
discoidin domain receptor tyrosine kinase 1
chr3_-_147966097 0.46 ENSRNOT00000009913
defensin beta 22
chr2_+_52301798 0.45 ENSRNOT00000091387
poly(A) binding protein interacting protein 1
chr12_-_30810964 0.42 ENSRNOT00000001235
ENSRNOT00000093237
ENSRNOT00000077977
splicing factor SWAP homolog
chr1_+_222519615 0.33 ENSRNOT00000083585
REST corepressor 2
chr1_-_242373764 0.32 ENSRNOT00000076544
family with sequence similarity 122A
chr14_+_64686793 0.31 ENSRNOT00000005894
ENSRNOT00000036646
adhesion G protein-coupled receptor A3
chr4_+_140092352 0.23 ENSRNOT00000008892
SET domain and mariner transposase fusion gene
chr4_-_147592699 0.05 ENSRNOT00000013831
Raf-1 proto-oncogene, serine/threonine kinase
chr1_-_198900375 0.02 ENSRNOT00000024969
zinc finger protein 689

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
11.0 33.0 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470)
4.2 12.7 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
4.2 12.6 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
3.5 24.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
3.2 45.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
3.1 12.4 GO:0033277 abortive mitotic cell cycle(GO:0033277)
3.1 9.2 GO:0010813 neuropeptide catabolic process(GO:0010813)
2.9 8.7 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
2.4 4.9 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
2.3 9.2 GO:0043490 malate-aspartate shuttle(GO:0043490) L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
2.0 7.8 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
1.9 11.4 GO:0042414 epinephrine metabolic process(GO:0042414)
1.9 5.6 GO:0001546 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
1.9 5.6 GO:0006543 glutamine catabolic process(GO:0006543)
1.8 9.0 GO:0001555 oocyte growth(GO:0001555)
1.8 5.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
1.7 7.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
1.7 5.2 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
1.7 8.4 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
1.6 9.4 GO:0003383 apical constriction(GO:0003383)
1.6 6.2 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
1.5 4.4 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
1.4 9.7 GO:0048539 bone marrow development(GO:0048539)
1.4 6.8 GO:1904401 cellular response to Thyroid stimulating hormone(GO:1904401)
1.3 6.7 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
1.3 6.6 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
1.3 5.2 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
1.3 5.1 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
1.2 7.3 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
1.2 7.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
1.1 13.7 GO:0045820 negative regulation of glycolytic process(GO:0045820)
1.1 3.4 GO:0003162 atrioventricular node development(GO:0003162)
1.1 5.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426) progesterone secretion(GO:0042701)
1.0 16.3 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
1.0 12.2 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.9 23.0 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.9 7.8 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.8 4.0 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.8 9.3 GO:0048664 neuron fate determination(GO:0048664)
0.8 10.1 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.7 12.5 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.6 1.9 GO:0042631 cellular response to water deprivation(GO:0042631)
0.6 7.0 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.6 2.9 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.6 5.2 GO:0080009 mRNA methylation(GO:0080009)
0.5 6.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.5 2.1 GO:0070475 rRNA base methylation(GO:0070475)
0.5 2.9 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.5 10.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.4 1.8 GO:1904378 protein K29-linked deubiquitination(GO:0035523) maintenance of unfolded protein(GO:0036506) protein K6-linked deubiquitination(GO:0044313) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.4 9.7 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.4 4.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.4 5.5 GO:0032836 glomerular basement membrane development(GO:0032836)
0.4 1.2 GO:0098749 cerebellar neuron development(GO:0098749)
0.4 2.8 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.4 4.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.4 5.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.3 10.9 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.3 0.7 GO:0003134 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) cell-cell signaling involved in cell fate commitment(GO:0045168) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.3 2.0 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.3 3.0 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.3 1.3 GO:0097117 guanylate kinase-associated protein clustering(GO:0097117)
0.3 9.2 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.3 18.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.3 5.0 GO:0019532 oxalate transport(GO:0019532) sulfate transmembrane transport(GO:1902358)
0.3 0.6 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.3 3.4 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.3 0.9 GO:0072602 interleukin-4 secretion(GO:0072602)
0.3 2.2 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.3 5.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.3 7.2 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.3 3.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2 0.5 GO:0035566 regulation of metanephros size(GO:0035566)
0.2 2.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 12.7 GO:0042130 negative regulation of T cell proliferation(GO:0042130)
0.2 2.0 GO:0006013 mannose metabolic process(GO:0006013)
0.2 2.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 6.4 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.1 2.6 GO:0006415 translational termination(GO:0006415)
0.1 1.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 5.6 GO:0060325 face morphogenesis(GO:0060325)
0.1 2.0 GO:0051639 actin filament network formation(GO:0051639)
0.1 7.3 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 0.9 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.1 1.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 6.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 3.4 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.1 6.2 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.1 0.5 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 4.6 GO:0006611 protein export from nucleus(GO:0006611)
0.1 3.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.2 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.1 7.7 GO:0019882 antigen processing and presentation(GO:0019882)
0.1 1.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1 5.1 GO:1901607 alpha-amino acid biosynthetic process(GO:1901607)
0.1 0.7 GO:0030238 male sex determination(GO:0030238)
0.1 1.0 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 4.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 2.1 GO:0048536 spleen development(GO:0048536)
0.1 0.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 3.5 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 4.8 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 3.0 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 6.7 GO:0051607 defense response to virus(GO:0051607)
0.0 4.3 GO:0042552 myelination(GO:0042552)
0.0 4.3 GO:0007030 Golgi organization(GO:0007030)
0.0 9.6 GO:0016485 protein processing(GO:0016485)
0.0 2.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.6 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 5.6 GO:0001889 liver development(GO:0001889)
0.0 1.0 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 1.7 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 2.9 GO:0006913 nucleocytoplasmic transport(GO:0006913)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 12.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
1.7 15.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
1.5 12.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
1.3 7.7 GO:1990111 spermatoproteasome complex(GO:1990111)
1.2 8.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
1.1 10.9 GO:0014731 spectrin(GO:0008091) spectrin-associated cytoskeleton(GO:0014731)
1.0 33.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.9 7.8 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.9 5.2 GO:0036396 MIS complex(GO:0036396)
0.8 3.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.7 9.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.7 9.0 GO:0044666 MLL3/4 complex(GO:0044666)
0.5 10.0 GO:0043196 varicosity(GO:0043196)
0.5 3.4 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.5 3.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.4 2.4 GO:1990393 3M complex(GO:1990393)
0.4 4.0 GO:0097418 neurofibrillary tangle(GO:0097418)
0.3 3.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.3 1.0 GO:0035101 FACT complex(GO:0035101)
0.2 5.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 2.3 GO:0033643 host cell part(GO:0033643)
0.2 7.0 GO:0099738 cell cortex region(GO:0099738)
0.2 6.5 GO:0031941 filamentous actin(GO:0031941)
0.2 4.9 GO:0042629 mast cell granule(GO:0042629)
0.2 5.5 GO:0005605 basal lamina(GO:0005605)
0.2 2.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.2 2.4 GO:0035102 PRC1 complex(GO:0035102)
0.2 3.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.2 4.9 GO:0005694 chromosome(GO:0005694)
0.1 14.5 GO:0005902 microvillus(GO:0005902)
0.1 11.1 GO:0005884 actin filament(GO:0005884)
0.1 14.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 13.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 5.7 GO:0015030 Cajal body(GO:0015030)
0.1 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 7.8 GO:0043198 dendritic shaft(GO:0043198)
0.1 9.2 GO:0043209 myelin sheath(GO:0043209)
0.1 3.4 GO:0016592 mediator complex(GO:0016592)
0.1 5.0 GO:0045095 keratin filament(GO:0045095)
0.1 0.5 GO:0030312 external encapsulating structure(GO:0030312)
0.1 5.7 GO:0005776 autophagosome(GO:0005776)
0.1 6.7 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 13.6 GO:0000785 chromatin(GO:0000785)
0.1 5.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 6.2 GO:0001726 ruffle(GO:0001726)
0.0 2.8 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 5.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 6.9 GO:0005925 focal adhesion(GO:0005925)
0.0 12.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 75.2 GO:0005654 nucleoplasm(GO:0005654)
0.0 10.3 GO:0031012 extracellular matrix(GO:0031012)
0.0 4.6 GO:0005874 microtubule(GO:0005874)
0.0 0.2 GO:0035861 site of double-strand break(GO:0035861)
0.0 5.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 59.5 GO:0005634 nucleus(GO:0005634)
0.0 4.1 GO:0043235 receptor complex(GO:0043235)
0.0 0.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 3.6 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 33.0 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
4.1 45.3 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
3.2 9.7 GO:0032427 GBD domain binding(GO:0032427)
2.6 7.8 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
2.5 12.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
1.9 5.6 GO:0004359 glutaminase activity(GO:0004359)
1.8 9.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
1.7 6.7 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
1.5 7.3 GO:1990932 5.8S rRNA binding(GO:1990932)
1.4 4.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
1.4 12.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
1.3 9.2 GO:0001595 angiotensin receptor activity(GO:0001595)
1.2 7.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
1.0 4.0 GO:0034618 arginine binding(GO:0034618)
0.9 5.4 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.8 10.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.8 2.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.7 2.1 GO:0008169 C-methyltransferase activity(GO:0008169)
0.7 5.5 GO:0043237 laminin-1 binding(GO:0043237)
0.6 12.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.6 5.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.5 4.7 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.5 22.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.5 10.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.5 5.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.5 5.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.5 7.3 GO:0035497 cAMP response element binding(GO:0035497)
0.4 4.0 GO:0098748 clathrin heavy chain binding(GO:0032050) clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.4 1.8 GO:1904288 BAT3 complex binding(GO:1904288)
0.4 2.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.4 3.0 GO:0034711 inhibin binding(GO:0034711)
0.4 16.7 GO:0004180 carboxypeptidase activity(GO:0004180)
0.4 1.9 GO:0015166 polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168)
0.4 5.1 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.4 7.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.3 2.8 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.3 7.0 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.3 5.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 10.4 GO:0004623 phospholipase A2 activity(GO:0004623)
0.3 5.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 6.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.3 7.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.3 7.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3 7.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 6.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 5.1 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.2 7.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 2.6 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 8.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 6.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 4.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 1.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 4.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 8.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 4.8 GO:0030506 ankyrin binding(GO:0030506)
0.2 2.8 GO:0097602 cullin family protein binding(GO:0097602)
0.2 3.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 3.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 1.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 11.4 GO:0008170 N-methyltransferase activity(GO:0008170)
0.1 6.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.9 GO:0045340 mercury ion binding(GO:0045340)
0.1 37.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 3.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 12.7 GO:0005178 integrin binding(GO:0005178)
0.1 2.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 2.0 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 8.3 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.1 5.8 GO:0030276 clathrin binding(GO:0030276)
0.1 10.3 GO:0017124 SH3 domain binding(GO:0017124)
0.1 9.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 3.4 GO:0042605 peptide antigen binding(GO:0042605)
0.1 23.7 GO:0030246 carbohydrate binding(GO:0030246)
0.1 2.0 GO:0003785 actin monomer binding(GO:0003785)
0.1 6.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 9.0 GO:0044212 regulatory region DNA binding(GO:0000975) transcription regulatory region DNA binding(GO:0044212)
0.1 4.3 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 6.4 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.1 1.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 1.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 1.0 GO:0031491 nucleosome binding(GO:0031491)
0.0 3.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.6 GO:0043274 phospholipase binding(GO:0043274)
0.0 27.5 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 10.1 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 6.8 GO:0005506 iron ion binding(GO:0005506)
0.0 0.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 2.9 GO:0008201 heparin binding(GO:0008201)
0.0 0.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 4.3 GO:0004866 endopeptidase inhibitor activity(GO:0004866)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 12.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.6 18.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.6 45.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.5 5.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.5 19.4 PID IFNG PATHWAY IFN-gamma pathway
0.5 5.6 PID ALK2 PATHWAY ALK2 signaling events
0.4 7.9 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.4 18.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.3 22.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.3 10.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.3 7.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.3 6.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.2 7.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.2 3.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 6.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.2 5.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 3.0 PID ALK1 PATHWAY ALK1 signaling events
0.1 6.2 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 5.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 18.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 15.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 4.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 3.4 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 6.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
1.7 31.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
1.4 24.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
1.2 45.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.9 23.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.7 12.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.7 10.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.6 10.0 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.6 10.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.5 5.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.5 9.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.4 5.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.4 3.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.3 5.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.3 8.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 6.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.3 7.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.3 6.9 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.3 14.4 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.3 2.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.3 6.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.2 5.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 12.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 3.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2 1.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 11.0 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.1 14.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 3.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 3.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 4.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 2.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 17.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 7.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 0.5 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 1.8 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 1.0 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 3.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.7 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways