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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Tfap2a

Z-value: 0.98

Motif logo

Transcription factors associated with Tfap2a

Gene Symbol Gene ID Gene Info
ENSRNOG00000015522 transcription factor AP-2 alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tfap2arn6_v1_chr17_+_24654902_246549020.323.0e-09Click!

Activity profile of Tfap2a motif

Sorted Z-values of Tfap2a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_60276794 21.12 ENSRNOT00000048509
solute carrier family 34 member 2
chr17_+_22619891 20.92 ENSRNOT00000060403
androgen-dependent TFPI-regulating protein
chr2_+_60920257 18.84 ENSRNOT00000025170
C1q and tumor necrosis factor related protein 3
chr2_-_195935878 18.62 ENSRNOT00000028440
cingulin
chr1_-_84145916 18.45 ENSRNOT00000081796
latent transforming growth factor beta binding protein 4
chr1_-_80716143 18.19 ENSRNOT00000092048
ENSRNOT00000025829
Cbl proto-oncogene C
chr10_-_88060561 17.65 ENSRNOT00000019133
keratin 19
chr10_+_104368247 15.51 ENSRNOT00000006519
LLGL2, scribble cell polarity complex component
chr4_+_120133713 15.23 ENSRNOT00000017240
GATA binding protein 2
chr4_+_72718458 14.68 ENSRNOT00000044780
Rho guanine nucleotide exchange factor 5
chr13_-_80745347 13.92 ENSRNOT00000041908
flavin containing monooxygenase 1
chr8_-_72836159 13.88 ENSRNOT00000024617
tropomyosin 1, alpha
chr4_+_168832910 12.82 ENSRNOT00000011134
G protein-coupled receptor, class C, group 5, member A
chr5_+_152559577 12.44 ENSRNOT00000082245
solute carrier family 30 member 2
chr15_-_48670257 12.36 ENSRNOT00000071464
frizzled class receptor 3
chr11_-_57993548 12.27 ENSRNOT00000002957
nectin cell adhesion molecule 3
chr5_-_169331163 12.20 ENSRNOT00000042301
espin
chr11_+_46009322 12.09 ENSRNOT00000002233
transmembrane protein 45A
chr7_-_49250953 11.71 ENSRNOT00000066975
ENSRNOT00000082141
acyl-CoA synthetase short-chain family member 3
chr14_-_2032593 11.67 ENSRNOT00000000037
fibroblast growth factor receptor-like 1
chr1_-_199377035 11.51 ENSRNOT00000026572
protease, serine, 8
chr10_-_105668593 11.46 ENSRNOT00000016622
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr3_-_55822551 11.38 ENSRNOT00000082624
LDL receptor related protein 2
chr9_+_88357556 11.13 ENSRNOT00000020669
collagen type IV alpha 3 chain
chr2_+_242882306 11.04 ENSRNOT00000013661
DNA-damage-inducible transcript 4-like
chr1_+_219233750 10.92 ENSRNOT00000024112
aminoacylase 3
chr7_-_117679219 10.91 ENSRNOT00000071522
solute carrier family 39 member 4
chr1_+_178636544 10.85 ENSRNOT00000092099
spondin 1
chr2_+_188543137 10.82 ENSRNOT00000027850
mucin 1, cell surface associated
chr13_-_80775230 10.77 ENSRNOT00000091389
ENSRNOT00000004762
flavin containing monooxygenase 2
chr2_+_242634399 10.76 ENSRNOT00000035700
endomucin
chr1_-_72461547 10.45 ENSRNOT00000022480
scavenger receptor cysteine rich family member with 5 domains
chr9_+_98073038 10.32 ENSRNOT00000026795
melanophilin
chr20_+_41266566 10.18 ENSRNOT00000000653
fyn-related Src family tyrosine kinase
chr2_+_199162745 10.15 ENSRNOT00000023488
gap junction protein, alpha 5
chr8_+_54925607 10.04 ENSRNOT00000059210
placenta expressed transcript 1
chr11_-_38088753 9.83 ENSRNOT00000002713
transmembrane protease, serine 2
chr3_+_109862117 9.69 ENSRNOT00000083351
ENSRNOT00000070912
thrombospondin 1
chr19_-_25134055 9.50 ENSRNOT00000007519
MISP family member 3
chr6_-_147172022 9.31 ENSRNOT00000080675
integrin subunit beta 8
chr5_+_58855773 9.21 ENSRNOT00000072869
RUN and SH3 domain containing 2
chr1_+_78933372 9.18 ENSRNOT00000029810
coiled-coil domain containing 8
chr4_+_175431904 9.13 ENSRNOT00000032843
phosphodiesterase 3A
chr5_+_159967839 8.88 ENSRNOT00000051317
heat shock protein family B (small) member 7
chr5_+_2813131 8.87 ENSRNOT00000009530
somatomedin B and thrombospondin, type 1 domain containing
chr8_-_40078165 8.77 ENSRNOT00000014866
sperm autoantigenic protein 17
chr14_+_86922223 8.68 ENSRNOT00000086468
receptor activity modifying protein 3
chr9_+_119353840 8.67 ENSRNOT00000085362
myomesin 1
chr14_+_86101277 8.62 ENSRNOT00000018846
AE binding protein 1
chr7_+_141249044 8.58 ENSRNOT00000084911
aquaporin 5
chr19_+_52647070 8.57 ENSRNOT00000068389
ENSRNOT00000087857
cysteine-rich secretory protein LCCL domain containing 2
chr1_+_264504591 8.41 ENSRNOT00000050076
paired box 2
chr6_+_105364668 8.29 ENSRNOT00000009513
ENSRNOT00000087090
tetratricopeptide repeat domain 9
chr2_+_114423533 7.87 ENSRNOT00000091221
solute carrier family 2 member 2
chr9_+_99998275 7.74 ENSRNOT00000074395
glypican 1
chr8_-_50531423 7.67 ENSRNOT00000090985
ENSRNOT00000074942
apolipoprotein C3
chr1_+_166433109 7.67 ENSRNOT00000026428
StAR-related lipid transfer domain containing 10
chr9_+_111028824 7.58 ENSRNOT00000041418
ENSRNOT00000056457
peptidylglycine alpha-amidating monooxygenase
chr2_-_142885604 7.56 ENSRNOT00000031487
Fras1 related extracellular matrix protein 2
chr1_-_189960073 7.54 ENSRNOT00000088482
crystallin, mu
chr9_+_68414339 7.52 ENSRNOT00000040778
par-3 family cell polarity regulator beta
chr18_+_53609214 7.48 ENSRNOT00000077443
solute carrier family 27 member 6
chr8_-_47404010 7.39 ENSRNOT00000038647
transmembrane protein 136
chr17_+_11953552 7.29 ENSRNOT00000090782
receptor tyrosine kinase-like orphan receptor 2
chr8_+_22189600 7.23 ENSRNOT00000061100
phosphodiesterase 4A
chr10_-_39228090 7.21 ENSRNOT00000011340
ENSRNOT00000086644
up-regulator of carnitine transporter, OCTN2
chr7_+_126619196 7.17 ENSRNOT00000030082
peroxisome proliferator activated receptor alpha
chr5_-_168123030 7.10 ENSRNOT00000092747
period circadian clock 3
chr18_-_40716686 7.08 ENSRNOT00000000172
cysteine dioxygenase type 1
chrX_+_72684329 6.93 ENSRNOT00000057644
DMRT-like family C1c1
chr13_+_80125391 6.90 ENSRNOT00000044190
microRNA 199a-2
chr1_+_134699299 6.88 ENSRNOT00000068766
repulsive guidance molecule family member A
chr16_-_18757918 6.86 ENSRNOT00000084172
surfactant protein D
chr11_+_75434197 6.85 ENSRNOT00000032569
Mab-21 domain containing 2
chr6_+_2969333 6.84 ENSRNOT00000047356
MORN repeat containing 2
chr4_+_100166863 6.83 ENSRNOT00000014505
surfactant protein B
chr13_+_75175254 6.81 ENSRNOT00000044008
SEC16 homolog B, endoplasmic reticulum export factor
chr13_-_72890841 6.81 ENSRNOT00000093726
similar to 6820428L09 protein
chr15_-_88036354 6.80 ENSRNOT00000014747
endothelin receptor type B
chr1_+_245237736 6.76 ENSRNOT00000035814
very low density lipoprotein receptor
chr2_-_21437193 6.75 ENSRNOT00000084002
creatine kinase, mitochondrial 2
chrX_-_37705263 6.74 ENSRNOT00000043666
mitogen-activated protein kinase kinase kinase 15
chr7_-_120026755 6.70 ENSRNOT00000077677
caspase recruitment domain family, member 10
chr1_-_216920625 6.69 ENSRNOT00000028119
oxysterol binding protein-like 5
chr1_-_72632185 6.66 ENSRNOT00000066383
transmembrane protein 190
chr3_+_119015412 6.64 ENSRNOT00000013605
solute carrier family 27 member 2
chr16_+_19097391 6.61 ENSRNOT00000018018
calreticulin 3
chr1_+_80321585 6.59 ENSRNOT00000022895
creatine kinase, M-type
chr4_-_45332420 6.58 ENSRNOT00000083039
wingless-type MMTV integration site family member 2
chr6_-_65319527 6.58 ENSRNOT00000005618
syntaxin binding protein 6
chr9_-_115382445 6.56 ENSRNOT00000091316
protein tyrosine phosphatase, receptor type, M
chr7_-_120027026 6.54 ENSRNOT00000011215
caspase recruitment domain family, member 10
chr4_+_121612332 6.54 ENSRNOT00000077374
ENSRNOT00000084494
thioredoxin reductase 3
chr6_-_127127413 6.53 ENSRNOT00000011906
proline rich membrane anchor 1
chr11_+_34557679 6.53 ENSRNOT00000002289
ripply transcriptional repressor 3
chr3_-_156905892 6.51 ENSRNOT00000022424
elastin microfibril interfacer 3
chr3_-_120106697 6.48 ENSRNOT00000020354
prominin 2
chr5_-_77248563 6.44 ENSRNOT00000052243
alpha-2u globulin PGCL5
chr3_-_11417546 6.43 ENSRNOT00000018776
lipocalin 2
chr1_+_101704746 6.42 ENSRNOT00000028564
family with sequence similarity 83, member E
chr1_-_164307084 6.40 ENSRNOT00000086091
serpin family H member 1
chrX_+_152999016 6.38 ENSRNOT00000088234
zinc finger protein 185
chr17_-_56909992 6.31 ENSRNOT00000021801
BMP and activin membrane-bound inhibitor
chr6_-_25616995 6.29 ENSRNOT00000077894
FOS like 2, AP-1 transcription factor subunit
chr10_+_89578212 6.28 ENSRNOT00000028178
ADP-ribosylation factor like GTPase 4D
chr8_+_59278262 6.26 ENSRNOT00000017053
DnaJ heat shock protein family (Hsp40) member A4
chr10_+_59743544 6.21 ENSRNOT00000093497
ENSRNOT00000056460
Tax1 binding protein 3
chrX_+_152196129 6.16 ENSRNOT00000087679
melanoma antigen, family A, 4
chr10_+_65448950 6.13 ENSRNOT00000082348
ENSRNOT00000037016
RAB34, member RAS oncogene family
chr1_+_81456984 6.05 ENSRNOT00000027075
ETHE1, persulfide dioxygenase
chr3_+_143172686 6.00 ENSRNOT00000006869
cystatin 9-like
chr5_-_168123395 5.94 ENSRNOT00000024932
period circadian clock 3
chr2_-_188672226 5.93 ENSRNOT00000027970
ENSRNOT00000050868
ADAM metallopeptidase domain 15
chr1_-_7480825 5.92 ENSRNOT00000048754
phosphatase and actin regulator 2
chr1_-_90520012 5.89 ENSRNOT00000028698
potassium channel tetramerization domain containing 15
chr10_-_98018014 5.88 ENSRNOT00000005367
FAM20A, golgi associated secretory pathway pseudokinase
chr6_+_122920317 5.88 ENSRNOT00000068595
ENSRNOT00000082856
tetratricopeptide repeat domain 8
chr13_-_86671515 5.85 ENSRNOT00000082869

chr10_-_91186054 5.84 ENSRNOT00000004140
phospholipase C, delta 3
chr1_+_236031988 5.79 ENSRNOT00000016164
proprotein convertase subtilisin/kexin type 5
chr6_+_26797126 5.78 ENSRNOT00000010586
cell growth regulator with EF hand domain 1
chrX_+_15035569 5.70 ENSRNOT00000006491
ENSRNOT00000078392
porcupine homolog (Drosophila)
chr10_+_49231730 5.68 ENSRNOT00000065335
tripartite motif-containing 16
chr1_+_220446425 5.63 ENSRNOT00000027339
endosialin-like
chr20_+_28078500 5.61 ENSRNOT00000030005
coiled-coil domain containing 138
chr3_-_160891190 5.55 ENSRNOT00000019386
syndecan 4
chr12_+_40553741 5.51 ENSRNOT00000057396
rCG21419-like
chr18_-_11858744 5.49 ENSRNOT00000061417
ENSRNOT00000082891
desmocollin 2
chr19_+_23389375 5.49 ENSRNOT00000018629
spalt-like transcription factor 1
chr1_-_90520344 5.48 ENSRNOT00000078598
potassium channel tetramerization domain containing 15
chr6_-_108596446 5.47 ENSRNOT00000031331
ENSRNOT00000077458
ENSRNOT00000082792
latent transforming growth factor beta binding protein 2
chr18_+_47740328 5.46 ENSRNOT00000025119
synuclein, alpha interacting protein
chr7_+_27174882 5.42 ENSRNOT00000051181
glycosyltransferase 8 domain containing 2
chr19_-_11302938 5.40 ENSRNOT00000038212

chr4_-_120467932 5.40 ENSRNOT00000018454
Sec61 translocon alpha 1 subunit
chr1_+_220353356 5.39 ENSRNOT00000080189
CD248 molecule
chr2_+_251863069 5.37 ENSRNOT00000036282
synapse defective Rho GTPase homolog 2
chr1_-_198794947 5.36 ENSRNOT00000024639
zinc finger protein 768
chr6_+_26399950 5.32 ENSRNOT00000085424
intraflagellar transport 172
chr19_+_50246402 5.29 ENSRNOT00000018795
hydroxysteroid (17-beta) dehydrogenase 2
chr8_-_22625959 5.26 ENSRNOT00000012138
Yip1 domain family, member 2
chr18_+_56364620 5.24 ENSRNOT00000068535
ENSRNOT00000086033
platelet derived growth factor receptor beta
chr1_+_82419947 5.20 ENSRNOT00000027964
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr13_+_75059927 5.17 ENSRNOT00000080801
hypothetical protein LOC680254
chr7_+_144052061 5.14 ENSRNOT00000020103
ENSRNOT00000091378
anti-Mullerian hormone receptor type 2
chr4_+_130172727 5.12 ENSRNOT00000051121
melanogenesis associated transcription factor
chr16_-_19097329 5.12 ENSRNOT00000030617
similar to 1700030K09Rik protein
chr1_+_266530477 5.10 ENSRNOT00000054699
cyclin and CBS domain divalent metal cation transport mediator 2
chr7_-_63578490 5.09 ENSRNOT00000007295
Ras association domain family member 3
chr11_+_70967439 5.05 ENSRNOT00000032518
IQ motif containing G
chr3_-_94686989 5.04 ENSRNOT00000016677
DEP domain containing 7
chr5_-_172769421 5.03 ENSRNOT00000021285
protein kinase C, zeta
chr8_-_108777717 5.03 ENSRNOT00000034188
interleukin 20 receptor subunit beta
chr8_-_63350269 5.01 ENSRNOT00000042681
Cd276 molecule
chr6_+_43234526 5.01 ENSRNOT00000086808
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr19_-_58399816 5.00 ENSRNOT00000026843
signal-induced proliferation-associated 1 like 2
chr11_-_61748768 4.95 ENSRNOT00000078879
coiled-coil domain containing 191
chr7_+_12619774 4.94 ENSRNOT00000015257
mediator complex subunit 16
chr10_-_105771972 4.94 ENSRNOT00000074286
ENSRNOT00000066137
matrix remodeling associated 7
chr4_-_179700130 4.94 ENSRNOT00000021306
lamin tail domain containing 1
chr5_-_77492013 4.93 ENSRNOT00000012293
alpha-2u globulin PGCL5
chr7_-_51353068 4.90 ENSRNOT00000008222
pro-apoptotic WT1 regulator
chr1_+_128924966 4.89 ENSRNOT00000019267
insulin-like growth factor 1 receptor
chr11_-_61748583 4.86 ENSRNOT00000093431
coiled-coil domain containing 191
chr6_+_127766470 4.82 ENSRNOT00000013138
serpin family A member 5
chr15_+_23665202 4.80 ENSRNOT00000089226
sterile alpha motif domain containing 4A
chr13_-_81214494 4.77 ENSRNOT00000004950
ENSRNOT00000082385
paired related homeobox 1
chr10_+_36099263 4.75 ENSRNOT00000083568
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr3_+_95233874 4.74 ENSRNOT00000079743
hypothetical protein LOC691083
chr4_+_42202838 4.68 ENSRNOT00000082453
MyoD family inhibitor domain containing
chr2_-_186480278 4.68 ENSRNOT00000031743
kin of IRRE like (Drosophila)
chr6_-_7961207 4.67 ENSRNOT00000007174
ATP binding cassette subfamily G member 5
chr4_+_44597123 4.63 ENSRNOT00000078250
caveolin 1
chr8_-_65587658 4.61 ENSRNOT00000091982
leucine rich repeat containing 49
chr1_+_15642153 4.59 ENSRNOT00000079845
microtubule-associated protein 7
chr8_+_116332796 4.57 ENSRNOT00000021408
hyaluronoglucosaminidase 1
chr10_-_47857326 4.57 ENSRNOT00000085703
ENSRNOT00000091963
epsin 2
chr10_+_63662986 4.56 ENSRNOT00000088722
scavenger receptor class F, member 1
chr9_+_111649631 4.56 ENSRNOT00000056430
FER tyrosine kinase
chr19_+_26173771 4.55 ENSRNOT00000005581
F-box and WD repeat domain containing 9
chr6_+_137288810 4.52 ENSRNOT00000030246
centrosomal protein 170B
chr10_-_56403188 4.48 ENSRNOT00000019947
cholinergic receptor nicotinic beta 1 subunit
chr12_+_19599834 4.47 ENSRNOT00000092039
ENSRNOT00000042006
stromal antigen 3
chr5_-_77342299 4.44 ENSRNOT00000075994
similar to alpha-2u-globulin
chr8_+_28352772 4.42 ENSRNOT00000012391
immunoglobulin superfamily, member 9B
chr6_-_99870024 4.41 ENSRNOT00000010043
RAB15, member RAS oncogene family
chr10_+_55138633 4.35 ENSRNOT00000057223
major facilitator superfamily domain containing 6-like
chr1_-_222178725 4.35 ENSRNOT00000028697
estrogen related receptor, alpha
chr1_+_65576535 4.31 ENSRNOT00000026575
solute carrier family 27 member 5
chr18_-_31071371 4.29 ENSRNOT00000060432
diaphanous-related formin 1
chr1_-_143535583 4.29 ENSRNOT00000087785
homer scaffolding protein 2
chr1_+_83711251 4.25 ENSRNOT00000028237
ENSRNOT00000092008
cytochrome P450, family 2, subfamily a, polypeptide 1
chr2_+_188844073 4.24 ENSRNOT00000028117
potassium calcium-activated channel subfamily N member 3
chr13_-_75059326 4.20 ENSRNOT00000089062
RAS protein activator like 2
chr14_-_8432195 4.18 ENSRNOT00000089800
Rho GTPase activating protein 24
chr7_-_3342491 4.17 ENSRNOT00000081756
retinol dehydrogenase 5
chr2_+_203200427 4.13 ENSRNOT00000020566
V-set domain containing T cell activation inhibitor 1
chr5_-_137372993 4.11 ENSRNOT00000092823
transmembrane protein 125
chr9_-_15582556 4.10 ENSRNOT00000020516
similar to AI661453 protein
chr5_-_77433847 4.07 ENSRNOT00000076906
ENSRNOT00000043056
similar to alpha-2u globulin PGCL2
major urinary protein 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 15.2 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725)
4.6 13.9 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
3.9 15.5 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
3.6 10.9 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
3.4 10.2 GO:0010643 cell communication by chemical coupling(GO:0010643)
3.2 9.7 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of cGMP-mediated signaling(GO:0010752)
3.0 21.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
2.9 14.7 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
2.8 31.0 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
2.8 8.4 GO:0035566 regulation of metanephros size(GO:0035566)
2.7 13.7 GO:0050828 regulation of liquid surface tension(GO:0050828)
2.7 18.9 GO:0033278 cell proliferation in midbrain(GO:0033278)
2.7 10.8 GO:0072592 oxygen metabolic process(GO:0072592)
2.7 18.8 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
2.6 10.5 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
2.6 7.7 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
2.6 10.3 GO:0014826 vein smooth muscle contraction(GO:0014826)
2.6 7.7 GO:0010982 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) regulation of high-density lipoprotein particle clearance(GO:0010982)
2.4 2.4 GO:0071579 regulation of zinc ion transport(GO:0071579)
2.4 7.1 GO:0042412 taurine biosynthetic process(GO:0042412)
2.2 11.1 GO:0048550 negative regulation of pinocytosis(GO:0048550)
2.2 6.6 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
2.1 6.4 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
2.0 9.9 GO:0009758 carbohydrate utilization(GO:0009758)
2.0 5.9 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
1.9 3.9 GO:0007172 signal complex assembly(GO:0007172)
1.9 7.6 GO:0031179 peptide modification(GO:0031179)
1.8 5.5 GO:2000384 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
1.8 9.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
1.8 7.3 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
1.8 7.2 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
1.7 12.2 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
1.7 6.8 GO:0034436 glycoprotein transport(GO:0034436)
1.7 5.0 GO:0001807 regulation of type IV hypersensitivity(GO:0001807)
1.7 5.0 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
1.6 4.9 GO:0043133 hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134) positive regulation of neuronal action potential(GO:1904457)
1.6 4.9 GO:1904193 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
1.6 3.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
1.5 13.9 GO:0070995 NADPH oxidation(GO:0070995)
1.5 6.1 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
1.5 1.5 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
1.4 5.6 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887) positive regulation of extracellular exosome assembly(GO:1903553)
1.4 12.3 GO:1902414 protein localization to cell junction(GO:1902414)
1.4 4.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
1.4 10.8 GO:0090240 negative regulation of cell adhesion mediated by integrin(GO:0033629) positive regulation of histone H4 acetylation(GO:0090240)
1.3 4.0 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.3 5.2 GO:0072277 cell migration involved in vasculogenesis(GO:0035441) VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
1.3 3.8 GO:0046078 dUMP metabolic process(GO:0046078)
1.3 3.8 GO:0072156 distal tubule morphogenesis(GO:0072156)
1.2 8.7 GO:0002074 extraocular skeletal muscle development(GO:0002074)
1.2 8.6 GO:0015670 carbon dioxide transport(GO:0015670)
1.2 3.6 GO:0016107 sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
1.2 4.8 GO:0061107 seminal vesicle development(GO:0061107)
1.2 3.6 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
1.2 5.9 GO:0044691 tooth eruption(GO:0044691)
1.2 2.4 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
1.2 3.5 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
1.1 4.6 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
1.1 4.6 GO:0050904 Kit signaling pathway(GO:0038109) diapedesis(GO:0050904)
1.1 12.4 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
1.1 3.4 GO:0051695 actin filament uncapping(GO:0051695)
1.1 3.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
1.1 8.9 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
1.1 3.3 GO:1901873 regulation of post-translational protein modification(GO:1901873)
1.1 4.4 GO:1902606 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
1.1 5.4 GO:0039019 pronephric nephron development(GO:0039019)
1.1 4.3 GO:0046951 ketone body biosynthetic process(GO:0046951)
1.1 11.7 GO:0060539 diaphragm development(GO:0060539)
1.1 3.2 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
1.0 3.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
1.0 5.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
1.0 6.1 GO:0044351 macropinocytosis(GO:0044351)
1.0 5.0 GO:2000664 positive regulation of T-helper 2 cell cytokine production(GO:2000553) positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-10 secretion(GO:2001181)
1.0 3.0 GO:0006114 glycerol biosynthetic process(GO:0006114)
1.0 6.9 GO:0009804 coumarin metabolic process(GO:0009804)
1.0 5.8 GO:0002001 renin secretion into blood stream(GO:0002001)
0.9 4.7 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
0.9 5.7 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.9 11.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.9 9.8 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.9 5.1 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.8 2.5 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) response to methamphetamine hydrochloride(GO:1904313)
0.8 2.4 GO:0006083 acetate metabolic process(GO:0006083) propionate metabolic process(GO:0019541)
0.8 2.4 GO:0006574 valine catabolic process(GO:0006574)
0.8 4.0 GO:0033026 negative regulation of mast cell apoptotic process(GO:0033026) mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.8 6.4 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.8 1.6 GO:0002930 trabecular meshwork development(GO:0002930)
0.8 6.3 GO:0001661 conditioned taste aversion(GO:0001661)
0.8 5.5 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.8 9.4 GO:0086103 G-protein coupled receptor signaling pathway involved in heart process(GO:0086103)
0.8 13.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.8 3.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.8 3.8 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.8 2.3 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.8 6.8 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.8 2.3 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.7 11.5 GO:0070633 transepithelial transport(GO:0070633)
0.7 7.2 GO:0060033 anatomical structure regression(GO:0060033)
0.7 2.9 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.7 4.9 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.7 1.4 GO:0038183 bile acid signaling pathway(GO:0038183)
0.7 4.1 GO:0072602 interleukin-4 secretion(GO:0072602)
0.7 7.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.7 2.0 GO:0098749 cerebellar neuron development(GO:0098749)
0.7 10.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.7 11.4 GO:0045056 transcytosis(GO:0045056)
0.7 5.3 GO:0061525 hindgut development(GO:0061525)
0.7 9.3 GO:0001573 ganglioside metabolic process(GO:0001573)
0.7 7.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.7 2.0 GO:0051012 microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.6 2.6 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.6 8.9 GO:0015693 magnesium ion transport(GO:0015693)
0.6 6.3 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.6 8.8 GO:0051601 exocyst localization(GO:0051601)
0.6 3.7 GO:0072675 osteoclast fusion(GO:0072675)
0.6 6.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.6 5.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.6 1.7 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.5 1.1 GO:0046066 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
0.5 6.5 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.5 1.6 GO:0006788 heme oxidation(GO:0006788)
0.5 11.5 GO:0097503 sialylation(GO:0097503)
0.5 1.6 GO:1990401 regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling(GO:0060683) embryonic lung development(GO:1990401)
0.5 3.5 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.5 5.5 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.5 6.4 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.5 3.4 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.5 2.4 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.5 14.2 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313)
0.5 1.4 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.5 6.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.5 5.0 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.5 3.2 GO:0046959 habituation(GO:0046959)
0.5 3.2 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.4 4.5 GO:0035095 behavioral response to nicotine(GO:0035095)
0.4 1.3 GO:0006589 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.4 2.2 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.4 4.8 GO:0048664 neuron fate determination(GO:0048664)
0.4 10.3 GO:0032400 melanosome localization(GO:0032400)
0.4 2.5 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.4 3.3 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.4 14.2 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.4 0.8 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.4 1.9 GO:0001552 ovarian follicle atresia(GO:0001552)
0.4 1.1 GO:0046356 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.4 1.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.4 10.8 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.4 1.4 GO:0042374 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.3 14.5 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.3 5.8 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.3 2.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3 1.4 GO:1904975 response to bleomycin(GO:1904975)
0.3 8.4 GO:0010842 retina layer formation(GO:0010842)
0.3 2.3 GO:0000103 sulfate assimilation(GO:0000103)
0.3 1.3 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.3 1.0 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.3 1.6 GO:0001582 detection of chemical stimulus involved in sensory perception of sweet taste(GO:0001582)
0.3 4.3 GO:0071420 cellular response to histamine(GO:0071420)
0.3 1.4 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.3 3.2 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.3 3.4 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.3 1.7 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.3 4.4 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.3 6.5 GO:0060037 pharyngeal system development(GO:0060037)
0.3 1.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.3 2.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.3 3.4 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.3 1.6 GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.3 8.8 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.3 7.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.3 4.3 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.2 4.6 GO:0033327 Leydig cell differentiation(GO:0033327)
0.2 10.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.2 2.9 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.2 0.9 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.2 1.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 0.7 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.2 0.9 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.2 2.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2 4.8 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.2 0.6 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.2 3.9 GO:0006828 manganese ion transport(GO:0006828)
0.2 2.8 GO:0031507 heterochromatin assembly(GO:0031507)
0.2 1.8 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.2 1.0 GO:0006102 isocitrate metabolic process(GO:0006102)
0.2 3.9 GO:0002385 organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385)
0.2 4.3 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.2 2.1 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.2 1.6 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.2 0.4 GO:0030186 melatonin metabolic process(GO:0030186)
0.2 0.4 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.2 2.1 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.2 1.0 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.2 2.8 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.2 1.5 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.2 2.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.2 4.9 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.2 0.5 GO:2001034 histone H3-K36 dimethylation(GO:0097676) positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 1.7 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 3.2 GO:0097435 fibril organization(GO:0097435)
0.1 4.8 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.3 GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.1 1.6 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 5.3 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 3.5 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 1.4 GO:0033622 integrin activation(GO:0033622)
0.1 0.7 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 0.9 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 4.9 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.1 3.9 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 0.6 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 5.9 GO:0015914 phospholipid transport(GO:0015914)
0.1 4.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 7.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.6 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 2.2 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1 1.0 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 4.5 GO:0007129 synapsis(GO:0007129)
0.1 2.3 GO:0044030 regulation of DNA methylation(GO:0044030)
0.1 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 1.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 2.1 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.1 1.5 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 1.0 GO:0097264 self proteolysis(GO:0097264)
0.1 0.8 GO:0015732 prostaglandin transport(GO:0015732)
0.1 0.3 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.1 2.3 GO:1901998 toxin transport(GO:1901998)
0.1 1.0 GO:0045116 protein neddylation(GO:0045116)
0.1 0.1 GO:0060527 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.1 1.8 GO:0019730 antimicrobial humoral response(GO:0019730)
0.1 7.1 GO:0009408 response to heat(GO:0009408)
0.1 3.1 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 1.4 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 1.4 GO:0035864 response to potassium ion(GO:0035864)
0.1 2.0 GO:0007032 endosome organization(GO:0007032)
0.1 2.4 GO:0048662 negative regulation of smooth muscle cell proliferation(GO:0048662)
0.1 6.1 GO:0006457 protein folding(GO:0006457)
0.1 3.9 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973) regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0 4.1 GO:0006497 protein lipidation(GO:0006497)
0.0 3.9 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.4 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133)
0.0 3.9 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 1.3 GO:1904377 positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.7 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.0 0.6 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.7 GO:0009251 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 1.2 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 2.6 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 1.4 GO:0070206 protein trimerization(GO:0070206)
0.0 0.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 1.0 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.8 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.3 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.3 GO:0042574 retinal metabolic process(GO:0042574)
0.0 2.0 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.3 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 1.2 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.7 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.7 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 1.7 GO:0046546 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.5 GO:1902652 cholesterol metabolic process(GO:0008203) secondary alcohol metabolic process(GO:1902652)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.5 GO:0007422 peripheral nervous system development(GO:0007422)
0.0 0.0 GO:0051461 negative regulation of histone deacetylation(GO:0031064) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.3 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
2.5 7.6 GO:0000802 transverse filament(GO:0000802)
2.5 17.7 GO:1990357 terminal web(GO:1990357)
2.0 13.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
1.7 6.7 GO:0002079 inner acrosomal membrane(GO:0002079)
1.6 6.5 GO:0071914 microspike(GO:0044393) prominosome(GO:0071914)
1.5 9.2 GO:1990393 3M complex(GO:1990393)
1.5 4.6 GO:0036117 hyaluranon cable(GO:0036117)
1.4 11.1 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
1.3 7.7 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
1.2 4.9 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
1.2 9.7 GO:0005577 fibrinogen complex(GO:0005577)
1.2 16.5 GO:0032426 stereocilium tip(GO:0032426)
1.1 10.3 GO:0016461 unconventional myosin complex(GO:0016461)
1.1 21.1 GO:0031528 microvillus membrane(GO:0031528)
0.9 3.8 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.9 12.8 GO:0032433 filopodium tip(GO:0032433)
0.9 5.3 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.8 2.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.6 5.0 GO:0043203 axon hillock(GO:0043203)
0.6 6.2 GO:0034464 BBSome(GO:0034464)
0.6 8.7 GO:0043202 lysosomal lumen(GO:0043202)
0.6 7.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.6 2.9 GO:0045252 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) oxoglutarate dehydrogenase complex(GO:0045252)
0.6 8.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.6 6.4 GO:0002177 manchette(GO:0002177)
0.6 5.8 GO:1990635 proximal dendrite(GO:1990635)
0.6 5.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.6 3.9 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.5 6.8 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.5 6.8 GO:0097208 alveolar lamellar body(GO:0097208)
0.5 43.9 GO:0044291 cell-cell contact zone(GO:0044291)
0.4 8.0 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.4 2.8 GO:0031094 platelet dense tubular network(GO:0031094)
0.4 2.0 GO:0070695 FHF complex(GO:0070695)
0.4 8.7 GO:0031430 M band(GO:0031430)
0.4 17.4 GO:0016459 myosin complex(GO:0016459)
0.4 4.0 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.4 5.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.3 23.8 GO:0005581 collagen trimer(GO:0005581)
0.3 3.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.3 14.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 3.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.3 2.8 GO:0005677 chromatin silencing complex(GO:0005677)
0.3 1.6 GO:1903767 sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
0.3 18.3 GO:0031225 anchored component of membrane(GO:0031225)
0.3 1.2 GO:0072487 MSL complex(GO:0072487)
0.3 1.7 GO:0005608 laminin-3 complex(GO:0005608)
0.3 5.6 GO:0043034 costamere(GO:0043034)
0.3 12.9 GO:0009925 basal plasma membrane(GO:0009925)
0.3 19.3 GO:0031526 brush border membrane(GO:0031526)
0.3 3.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3 6.7 GO:0034451 centriolar satellite(GO:0034451)
0.3 0.8 GO:1902560 GMP reductase complex(GO:1902560)
0.3 6.6 GO:0000145 exocyst(GO:0000145)
0.3 12.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 1.7 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 3.9 GO:0030061 mitochondrial crista(GO:0030061)
0.2 6.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 2.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 2.7 GO:0030008 TRAPP complex(GO:0030008)
0.2 4.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 4.0 GO:0005614 interstitial matrix(GO:0005614)
0.2 0.6 GO:1990462 omegasome membrane(GO:1903349) omegasome(GO:1990462)
0.2 1.4 GO:0001651 dense fibrillar component(GO:0001651)
0.2 1.4 GO:0031105 septin complex(GO:0031105) sperm annulus(GO:0097227)
0.2 1.5 GO:0031931 TORC1 complex(GO:0031931)
0.2 2.0 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 50.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 0.7 GO:0000938 GARP complex(GO:0000938) EARP complex(GO:1990745)
0.2 1.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 2.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 9.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 6.1 GO:0045171 intercellular bridge(GO:0045171)
0.1 6.9 GO:0015030 Cajal body(GO:0015030)
0.1 3.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.6 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 5.6 GO:0016592 mediator complex(GO:0016592)
0.1 2.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 2.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 6.6 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 4.3 GO:0005903 brush border(GO:0005903)
0.1 3.2 GO:0035869 ciliary transition zone(GO:0035869)
0.1 0.4 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.5 GO:0033268 node of Ranvier(GO:0033268)
0.1 1.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.7 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 25.0 GO:0016324 apical plasma membrane(GO:0016324)
0.1 6.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 12.2 GO:0001650 fibrillar center(GO:0001650)
0.1 3.0 GO:0005902 microvillus(GO:0005902)
0.1 1.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 4.1 GO:0005884 actin filament(GO:0005884)
0.1 5.7 GO:0030018 Z disc(GO:0030018)
0.1 11.1 GO:0005770 late endosome(GO:0005770)
0.1 7.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 0.7 GO:0042555 MCM complex(GO:0042555)
0.1 1.4 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 0.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 3.1 GO:0030175 filopodium(GO:0030175)
0.0 7.4 GO:0031012 extracellular matrix(GO:0031012)
0.0 2.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 3.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 2.0 GO:0030016 myofibril(GO:0030016)
0.0 7.5 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 1.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 16.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 2.4 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 21.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
3.6 10.9 GO:0004046 aminoacylase activity(GO:0004046)
3.5 17.4 GO:0070052 collagen V binding(GO:0070052)
2.6 5.1 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
2.6 7.7 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
2.5 10.2 GO:0086077 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
2.3 6.8 GO:0034437 glycoprotein transporter activity(GO:0034437)
2.1 24.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
2.0 20.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
2.0 11.7 GO:0042954 lipoprotein transporter activity(GO:0042954)
1.9 7.6 GO:0016842 amidine-lyase activity(GO:0016842)
1.7 5.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
1.6 7.9 GO:0005550 pheromone binding(GO:0005550)
1.5 11.7 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
1.4 6.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.3 4.0 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
1.3 3.9 GO:0042015 interleukin-20 binding(GO:0042015)
1.2 8.6 GO:0004111 creatine kinase activity(GO:0004111)
1.2 3.6 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
1.2 4.8 GO:0032190 acrosin binding(GO:0032190)
1.2 3.6 GO:0035939 microsatellite binding(GO:0035939)
1.2 3.5 GO:0004956 prostaglandin D receptor activity(GO:0004956)
1.2 3.5 GO:0031708 endothelin B receptor binding(GO:0031708)
1.1 23.7 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
1.1 3.3 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
1.0 5.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
1.0 29.2 GO:0017147 Wnt-protein binding(GO:0017147)
1.0 5.0 GO:0004962 endothelin receptor activity(GO:0004962)
1.0 15.6 GO:0015026 coreceptor activity(GO:0015026)
0.9 7.9 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.8 3.3 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.8 23.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.8 2.3 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.8 2.3 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.8 13.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.8 5.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.7 2.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.7 2.2 GO:0016414 carnitine O-octanoyltransferase activity(GO:0008458) O-octanoyltransferase activity(GO:0016414)
0.7 6.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.7 6.5 GO:0043495 protein anchor(GO:0043495)
0.7 5.7 GO:0051525 NFAT protein binding(GO:0051525)
0.7 31.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.7 18.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.6 5.7 GO:0019966 interleukin-1 binding(GO:0019966)
0.6 7.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.6 6.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.6 3.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.6 8.6 GO:0015250 water channel activity(GO:0015250)
0.6 2.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.6 4.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.6 4.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.6 1.7 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.6 3.9 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.6 4.4 GO:0004966 galanin receptor activity(GO:0004966)
0.5 4.9 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.5 4.9 GO:0043559 insulin binding(GO:0043559)
0.5 1.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.5 3.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.5 3.7 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.5 4.7 GO:0030957 Tat protein binding(GO:0030957)
0.5 1.5 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.5 3.0 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.5 11.5 GO:0008373 sialyltransferase activity(GO:0008373)
0.5 16.0 GO:0001968 fibronectin binding(GO:0001968)
0.5 4.7 GO:0017127 cholesterol transporter activity(GO:0017127)
0.5 1.4 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.5 6.6 GO:0051787 misfolded protein binding(GO:0051787)
0.5 6.5 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.5 15.3 GO:0005109 frizzled binding(GO:0005109)
0.5 5.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.5 6.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.4 1.3 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.4 8.9 GO:0031005 filamin binding(GO:0031005)
0.4 10.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.4 2.4 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.4 3.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.4 1.6 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.4 8.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.4 6.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.4 1.5 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.4 1.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.4 3.9 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.4 4.6 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.4 4.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.3 1.4 GO:0005499 vitamin D binding(GO:0005499) bile acid receptor activity(GO:0038181) vitamin D response element binding(GO:0070644)
0.3 3.8 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.3 3.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.3 4.6 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.3 1.0 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.3 3.9 GO:0008432 JUN kinase binding(GO:0008432)
0.3 8.7 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.3 2.3 GO:0008430 selenium binding(GO:0008430)
0.3 13.2 GO:0015485 cholesterol binding(GO:0015485)
0.3 6.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3 2.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.3 2.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.3 12.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.3 5.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.3 1.4 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.3 1.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.3 4.8 GO:0005522 profilin binding(GO:0005522)
0.3 0.8 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.3 4.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.3 7.6 GO:0030371 translation repressor activity(GO:0030371)
0.3 6.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.3 4.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.3 2.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.3 1.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.2 3.0 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.2 3.0 GO:0004000 adenosine deaminase activity(GO:0004000)
0.2 6.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 3.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 3.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 4.0 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 1.4 GO:0030274 LIM domain binding(GO:0030274)
0.2 5.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.2 0.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.2 2.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.2 3.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 3.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 4.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.2 3.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 0.7 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 2.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 4.3 GO:0071837 HMG box domain binding(GO:0071837)
0.2 11.0 GO:0051082 unfolded protein binding(GO:0051082)
0.2 5.3 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.2 1.0 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 0.9 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2 1.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 2.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 1.2 GO:0050693 LBD domain binding(GO:0050693)
0.1 2.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 12.3 GO:0008013 beta-catenin binding(GO:0008013)
0.1 2.1 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.7 GO:0071253 connexin binding(GO:0071253)
0.1 1.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 2.5 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 6.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 3.9 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 1.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.9 GO:0016421 CoA carboxylase activity(GO:0016421)
0.1 10.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.7 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 1.6 GO:0016805 dipeptidase activity(GO:0016805)
0.1 1.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 18.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 8.1 GO:0002039 p53 binding(GO:0002039)
0.1 6.5 GO:0048029 monosaccharide binding(GO:0048029)
0.1 1.6 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 1.4 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 11.5 GO:0008201 heparin binding(GO:0008201)
0.1 0.7 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 2.4 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.3 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1 0.4 GO:0034452 dynactin binding(GO:0034452)
0.1 4.9 GO:0043621 protein self-association(GO:0043621)
0.1 1.6 GO:0008199 ferric iron binding(GO:0008199)
0.1 7.7 GO:0002020 protease binding(GO:0002020)
0.1 3.4 GO:0005496 steroid binding(GO:0005496)
0.1 3.9 GO:0043022 ribosome binding(GO:0043022)
0.1 3.4 GO:0051018 protein kinase A binding(GO:0051018)
0.1 2.6 GO:0070888 E-box binding(GO:0070888)
0.1 12.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.9 GO:0051378 serotonin binding(GO:0051378)
0.1 5.6 GO:0017124 SH3 domain binding(GO:0017124)
0.1 4.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 2.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.5 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 4.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 11.3 GO:0045296 cadherin binding(GO:0045296)
0.0 1.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.4 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 2.3 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.5 GO:0031402 sodium ion binding(GO:0031402)
0.0 1.1 GO:0030145 manganese ion binding(GO:0030145)
0.0 1.5 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 6.0 GO:0016757 transferase activity, transferring glycosyl groups(GO:0016757)
0.0 4.8 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.1 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 3.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 2.4 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 80.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.5 13.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.5 9.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.5 10.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.4 1.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.4 6.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.4 20.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.4 7.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.4 14.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.4 21.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.3 4.6 PID ALK2 PATHWAY ALK2 signaling events
0.3 64.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.3 9.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.3 3.9 PID EPO PATHWAY EPO signaling pathway
0.3 12.7 PID BMP PATHWAY BMP receptor signaling
0.3 4.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.3 14.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.3 21.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.3 11.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.2 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 6.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 56.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 2.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 1.6 ST JAK STAT PATHWAY Jak-STAT Pathway
0.2 10.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 8.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 4.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.2 2.3 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 7.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 3.0 PID ENDOTHELIN PATHWAY Endothelins
0.1 2.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 5.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 1.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 2.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 2.2 PID BARD1 PATHWAY BARD1 signaling events
0.1 0.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.0 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.6 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 23.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
1.0 5.8 REACTOME SIGNALLING BY NGF Genes involved in Signalling by NGF
0.9 10.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.9 17.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.9 16.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.8 11.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.7 8.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.7 5.4 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.6 10.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.6 15.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.6 10.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.5 4.6 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.5 22.8 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.5 11.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.5 28.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.5 7.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.5 6.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.5 13.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.4 4.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 2.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.4 2.9 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.3 4.0 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.3 1.3 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.3 3.9 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.3 23.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.3 4.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3 4.7 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.3 3.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.3 26.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.3 4.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.3 7.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 3.9 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.2 2.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 2.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 2.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 20.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 3.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 2.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 17.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 2.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 2.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.5 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 1.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 4.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 3.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 2.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 5.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 3.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 0.7 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 0.9 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 3.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 2.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 0.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 7.1 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.9 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.9 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 2.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.8 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.9 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 2.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 1.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation