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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Tcf7_Tcf7l2

Z-value: 0.86

Motif logo

Transcription factors associated with Tcf7_Tcf7l2

Gene Symbol Gene ID Gene Info
ENSRNOG00000005872 transcription factor 7 (T-cell specific, HMG-box)
ENSRNOG00000049232 transcription factor 7 like 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
AABR07007000.1rn6_v1_chr1_-_276012351_276012351-0.108.2e-02Click!
Tcf7rn6_v1_chr10_-_37645802_37645802-0.063.1e-01Click!

Activity profile of Tcf7_Tcf7l2 motif

Sorted Z-values of Tcf7_Tcf7l2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_78985990 35.96 ENSRNOT00000009248
alpha-1-microglobulin/bikunin precursor
chr13_-_56877611 34.55 ENSRNOT00000079040
ENSRNOT00000017195
complement factor H-related 1
chrX_+_143097525 32.32 ENSRNOT00000004559
coagulation factor IX
chr4_+_65110746 28.02 ENSRNOT00000017675
aldo-keto reductase family 1, member D1
chr10_-_109840047 27.27 ENSRNOT00000054947
NOTUM, palmitoleoyl-protein carboxylesterase
chr7_-_143538579 23.75 ENSRNOT00000081518
keratin 79
chr17_+_22619891 21.11 ENSRNOT00000060403
androgen-dependent TFPI-regulating protein
chr4_+_122244711 17.64 ENSRNOT00000038251
urocanate hydratase 1
chr9_+_9721105 17.05 ENSRNOT00000073042
ENSRNOT00000075494
complement C3
chr5_-_50193571 16.65 ENSRNOT00000051243
cilia and flagella associated protein 206
chr4_+_172119331 16.12 ENSRNOT00000010579
microsomal glutathione S-transferase 1
chr19_-_41686229 15.59 ENSRNOT00000022721
tyrosine aminotransferase
chr6_+_127743971 14.80 ENSRNOT00000013045
serpin family A member 4
chr4_+_99063181 13.99 ENSRNOT00000008840
fatty acid binding protein 1
chr17_+_72160735 13.29 ENSRNOT00000038817
inter-alpha-trypsin inhibitor heavy chain 2
chr7_+_117759083 13.22 ENSRNOT00000050556
glutamic--pyruvic transaminase
chr10_+_90085559 13.10 ENSRNOT00000028332
N-acetylglutamate synthase
chr3_-_2719513 12.90 ENSRNOT00000020997
lipocalin 12
chr3_-_2719135 12.75 ENSRNOT00000080257
lipocalin 12
chr6_+_127927650 12.27 ENSRNOT00000057271
serine protease inhibitor A3F-like
chr2_-_181905300 12.21 ENSRNOT00000035411
lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
chr8_-_50539331 12.19 ENSRNOT00000088997

chr17_+_8489266 11.98 ENSRNOT00000016252
leukocyte cell-derived chemotaxin 2
chr18_+_46148849 11.98 ENSRNOT00000026724
proline rich 16
chr7_-_70661891 11.38 ENSRNOT00000010240
inhibin beta C subunit
chr1_-_76722965 11.06 ENSRNOT00000052129
alcohol sulfotransferase-like
chr1_+_84304228 10.90 ENSRNOT00000024771
periaxin
chr6_+_129052503 10.81 ENSRNOT00000044152
similar to BC049975 protein
chr11_+_67555658 10.78 ENSRNOT00000039075
cystatin A (stefin A)
chr8_+_50537009 10.77 ENSRNOT00000080658
apolipoprotein A4
chr1_-_52894832 10.50 ENSRNOT00000016471
T brachyury transcription factor
chr15_-_47338976 10.18 ENSRNOT00000016562
similar to 4930578I06Rik protein
chr17_+_9736577 10.18 ENSRNOT00000066586
coagulation factor XII
chr3_-_14112851 10.03 ENSRNOT00000092736
complement C5
chr7_+_1206648 9.91 ENSRNOT00000073689
protein S (alpha)
chr5_-_140657745 9.77 ENSRNOT00000019080
major facilitator superfamily domain containing 2A
chr13_-_56958549 9.71 ENSRNOT00000017293
ENSRNOT00000083912
similar to complement factor H-related protein
chr12_+_35612896 9.57 ENSRNOT00000073223

chr10_-_98294522 9.49 ENSRNOT00000005489
ATP binding cassette subfamily A member 8
chr4_-_78759408 9.42 ENSRNOT00000050994
insulin-like growth factor 2 mRNA binding protein 3
chr10_-_82209459 9.35 ENSRNOT00000004377
spermatogenesis associated 20
chr10_+_53778662 9.27 ENSRNOT00000045718
myosin heavy chain 2
chr20_-_14193690 9.03 ENSRNOT00000058237
beta-ureidopropionase 1
chr1_-_52962388 8.51 ENSRNOT00000033685
brachyury 2
chr13_-_53870428 8.27 ENSRNOT00000000812
nuclear receptor subfamily 5, group A, member 2
chr2_+_221823687 8.24 ENSRNOT00000072735
dihydropyrimidine dehydrogenase
chr7_-_139872900 7.82 ENSRNOT00000046402
H1 histone family, member N, testis-specific
chr5_+_68908892 7.60 ENSRNOT00000007515
similar to RIKEN cDNA 4930547C10
chr7_-_123655896 7.59 ENSRNOT00000012413
cytochrome P450, family 2, subfamily d, polypeptide 2
chr12_-_19114399 7.58 ENSRNOT00000073099
cytochrome P450, family 3, subfamily a, polypeptide 9
chr20_+_13778178 7.55 ENSRNOT00000058314
glutathione S-transferase, theta 4
chr5_+_165415136 7.50 ENSRNOT00000016317
ENSRNOT00000079407
mannan-binding lectin serine peptidase 2
chr7_+_116655145 7.48 ENSRNOT00000009823
zinc finger protein 41
chr4_+_133540540 7.37 ENSRNOT00000073232

chr14_-_18839420 7.26 ENSRNOT00000034090
chemokine (C-X-C motif) ligand 3
chr6_+_108123816 7.23 ENSRNOT00000089242
ENSRNOT00000063900
basal body orientation factor 1
chr16_-_18643309 7.23 ENSRNOT00000031680
DPY30 domain containing 2
chr9_+_95256627 7.16 ENSRNOT00000025291
UDP glucuronosyltransferase family 1 member A5
chr1_+_229030233 7.07 ENSRNOT00000084503
glycine-N-acyltransferase-like 1
chr18_-_13183263 6.98 ENSRNOT00000050933
coiled-coil domain containing 178
chr13_+_27238767 6.81 ENSRNOT00000003495
serpin family B member 11
chr2_-_201678244 6.78 ENSRNOT00000071087

chr17_-_2827001 6.61 ENSRNOT00000047872
protease, serine, 47
chr1_+_264741911 6.61 ENSRNOT00000019956
semaphorin 4G
chr11_+_54137639 6.58 ENSRNOT00000066343
leukocyte surface antigen CD47-like
chr13_-_50499060 6.58 ENSRNOT00000065347
ENSRNOT00000076924
ethanolamine kinase 2
chr1_-_4550768 6.58 ENSRNOT00000061954
androglobin
chr8_-_112648880 6.53 ENSRNOT00000015265
atypical chemokine receptor 4
chr1_-_164142206 6.50 ENSRNOT00000081669
diacylglycerol O-acyltransferase 2
chr4_-_101156576 6.50 ENSRNOT00000020894
dynein, axonemal, heavy chain 6
chr1_+_128614138 6.48 ENSRNOT00000076227
ENSRNOT00000078707
tetratricopeptide repeat domain 23
chr2_-_98610368 6.48 ENSRNOT00000011641
zinc finger homeobox 4
chr2_-_208633945 6.48 ENSRNOT00000049155
primary cilia formation
chr17_-_43504604 6.44 ENSRNOT00000083829
ENSRNOT00000066313
solute carrier family 17 member 1
chr10_-_46593009 6.33 ENSRNOT00000047053
sterol regulatory element binding transcription factor 1
chr2_-_155176260 6.25 ENSRNOT00000071864

chr13_+_75177965 6.20 ENSRNOT00000007321
SEC16 homolog B, endoplasmic reticulum export factor
chr4_-_101393329 6.19 ENSRNOT00000007636
similar to RIKEN cDNA 4931417E11
chr2_+_93712992 5.95 ENSRNOT00000059326
fatty acid binding protein 12
chr9_+_76913639 5.90 ENSRNOT00000089203

chr1_+_257970345 5.88 ENSRNOT00000088853
cytochrome P450, subfamily 2, polypeptide 11
chr4_+_70755795 5.87 ENSRNOT00000043527
similar to Anionic trypsin II precursor (Pretrypsinogen II)
chr14_-_86190659 5.80 ENSRNOT00000086474
glucokinase
chr10_+_89285855 5.69 ENSRNOT00000028033
glucose-6-phosphatase, catalytic subunit
chr10_-_88009576 5.67 ENSRNOT00000018566
keratin 35
chr15_+_35032049 5.52 ENSRNOT00000091757
mast cell protease 2
chr2_+_188449210 5.52 ENSRNOT00000027700
pyruvate kinase, liver and RBC
chr3_+_148510779 5.47 ENSRNOT00000012156
XK related 7
chr14_+_13751231 5.17 ENSRNOT00000044244
glycerol kinase 2
chr12_+_24158766 5.08 ENSRNOT00000001963
C-C motif chemokine ligand 26
chr4_-_161278293 4.86 ENSRNOT00000050332

chr7_-_20070772 4.79 ENSRNOT00000071008
sperm motility kinase W-like
chr18_-_786674 4.76 ENSRNOT00000021955
centrin 1
chr8_+_2659865 4.72 ENSRNOT00000088553
ENSRNOT00000010243
caspase 12
chr9_+_95161157 4.72 ENSRNOT00000071200
UDP glucuronosyltransferase family 1 member A5
chr18_-_41899450 4.69 ENSRNOT00000057099
similar to hypothetical protein 4930474N05
chr10_-_74413745 4.62 ENSRNOT00000038296
proline rich 11
chr17_-_88095729 4.58 ENSRNOT00000025140
enkurin, TRPC channel interacting protein
chr1_-_248377093 4.58 ENSRNOT00000067612
glycine decarboxylase
chr20_+_8109635 4.54 ENSRNOT00000000609
armadillo repeat containing 12
chr10_+_58875826 4.53 ENSRNOT00000020071
F-box protein 39
chr4_-_69149520 4.42 ENSRNOT00000017611
protease, serine, 58
chr4_-_77489535 4.39 ENSRNOT00000008728
protein disulfide isomerase family A, member 4
chr10_-_105412627 4.38 ENSRNOT00000034817
glutamine rich 2
chr7_+_54859104 4.34 ENSRNOT00000087341
calcyphosine 2
chr1_-_82236179 4.31 ENSRNOT00000027845
cornifelin
chr10_-_88152064 4.29 ENSRNOT00000019477
keratin 16
chr1_-_101198801 4.24 ENSRNOT00000037998
coiled-coil domain containing 155
chr14_-_92495894 4.14 ENSRNOT00000064483
cordon-bleu WH2 repeat protein
chr4_+_7144669 4.01 ENSRNOT00000077682
ENSRNOT00000014998
IQ motif containing with AAA domain 1 like
chr13_-_36022197 3.97 ENSRNOT00000091280
cilia and flagella associated protein 221
chr17_-_389967 3.97 ENSRNOT00000023865
fructose-bisphosphatase 2
chr3_-_134406576 3.94 ENSRNOT00000081589
SEL1L2 ERAD E3 ligase adaptor subunit
chr19_+_21541742 3.83 ENSRNOT00000021095
ENSRNOT00000042077
ATP binding cassette subfamily C member 12
chr3_+_138974871 3.81 ENSRNOT00000012524
SCP2 sterol-binding domain containing 1
chr20_+_9313271 3.80 ENSRNOT00000071939
ENSRNOT00000000651
dynein, axonemal, heavy chain 8
chr12_-_52596076 3.74 ENSRNOT00000056639
checkpoint with forkhead and ring finger domains
chr1_+_80880856 3.71 ENSRNOT00000026060
carcinoembryonic antigen-related cell adhesion molecule 20
chr9_-_70450170 3.60 ENSRNOT00000017207
malate dehydrogenase 1B
chr12_-_30083824 3.59 ENSRNOT00000084968
tyrosylprotein sulfotransferase 1
chr6_-_140102325 3.57 ENSRNOT00000072238

chr11_-_61530567 3.56 ENSRNOT00000076277
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr16_-_81309954 3.56 ENSRNOT00000092361
similar to RIKEN cDNA 1700029H14
chr4_+_159410799 3.55 ENSRNOT00000079225
A-kinase anchoring protein 3
chr7_+_54859326 3.50 ENSRNOT00000039141
calcyphosine 2
chr18_-_40134504 3.49 ENSRNOT00000022294
tripartite motif-containing 36
chr9_-_82195722 3.45 ENSRNOT00000077085
ENSRNOT00000084276
cilia and flagella associated protein 65
chr10_+_38104558 3.44 ENSRNOT00000067809
follistatin-like 4
chr13_-_36174908 3.42 ENSRNOT00000072295
diazepam binding inhibitor, acyl-CoA binding protein
chr1_-_189238776 3.34 ENSRNOT00000020817
protein disulfide isomerase-like, testis expressed
chr3_-_149356160 3.33 ENSRNOT00000037589
ENSRNOT00000081775
Sad1 and UNC84 domain containing 5
chr16_+_3851270 3.30 ENSRNOT00000014964
placenta-specific 9
chr1_+_81474553 3.29 ENSRNOT00000083493
pleckstrin homology-like domain, family B, member 3
chr1_-_212021567 3.28 ENSRNOT00000029027
cilia and flagella associated protein 46
chr3_+_56766475 3.27 ENSRNOT00000078819
Sp5 transcription factor
chr8_-_27907911 3.26 ENSRNOT00000010045
galactosidase, beta 1-like 3
chr4_-_39711271 3.24 ENSRNOT00000029602
von Willebrand factor D and EGF domains
chr10_-_87232723 3.23 ENSRNOT00000015150
keratin 25
chr2_+_154921999 3.23 ENSRNOT00000057620
similar to GTPase activating protein testicular GAP1
chr19_-_38120578 3.22 ENSRNOT00000026873
epithelial splicing regulatory protein 2
chr10_-_91291774 3.19 ENSRNOT00000004356
rCG33642-like
chr10_-_87346062 3.17 ENSRNOT00000077397
keratin 20
chr9_-_70449796 3.15 ENSRNOT00000086391
malate dehydrogenase 1B
chr3_+_80021440 3.13 ENSRNOT00000018620
acid phosphatase 2, lysosomal
chr10_+_97212432 3.13 ENSRNOT00000088599
axin 2
chr6_-_138536162 3.11 ENSRNOT00000083031

chr10_-_37645802 3.11 ENSRNOT00000008022
transcription factor 7 (T-cell specific, HMG-box)
chr8_+_56451240 3.09 ENSRNOT00000085278
mitochondrial ribosomal protein L1-like
chr4_+_82370997 3.09 ENSRNOT00000072934
even-skipped homeobox 1
chr2_+_222021103 3.07 ENSRNOT00000086125
dihydropyrimidine dehydrogenase
chr1_-_101210675 3.07 ENSRNOT00000028082
dickkopf like acrosomal protein 1
chr10_-_93679974 3.06 ENSRNOT00000009316
membrane associated ring-CH-type finger 10
chr1_-_54854353 3.05 ENSRNOT00000072895
sperm motility kinase 2A
chr4_+_149908375 3.04 ENSRNOT00000019504
uncharacterized LOC100909657
chr5_+_160095427 3.02 ENSRNOT00000077609

chr2_+_237679792 3.02 ENSRNOT00000064628
GIMAP family P-loop NTPase domain containing 1
chr7_+_37812831 3.01 ENSRNOT00000005910
BTG anti-proliferation factor 1
chr7_-_49732764 3.00 ENSRNOT00000006453
myogenic factor 5
chrX_+_63897664 2.99 ENSRNOT00000089271
protein gar2-like
chr1_+_185863043 2.94 ENSRNOT00000079072
SRY box 6
chr6_+_26546924 2.94 ENSRNOT00000007763
eukaryotic translation initiation factor 2B subunit delta
chr8_+_118744229 2.93 ENSRNOT00000028364
kinesin family member 9
chr6_-_61405195 2.90 ENSRNOT00000008655
leucine rich repeat neuronal 3
chr17_-_43543172 2.87 ENSRNOT00000080684
ENSRNOT00000029626
ENSRNOT00000082719
solute carrier family 17 member 3
chr1_+_252409268 2.86 ENSRNOT00000026219
lipase, family member M
chr1_-_275882444 2.84 ENSRNOT00000083215
glycerol-3-phosphate acyltransferase, mitochondrial
chr2_+_188449718 2.80 ENSRNOT00000065791
pyruvate kinase, liver and RBC
chr2_-_90568486 2.80 ENSRNOT00000059380
uncharacterized LOC100910852
chr1_+_202432366 2.80 ENSRNOT00000027681
phospholipid phosphatase 4
chr6_+_1147012 2.79 ENSRNOT00000006360
vitrin
chr1_-_31936537 2.78 ENSRNOT00000060971
zinc finger, DHHC-type containing 11
chr18_+_16616937 2.77 ENSRNOT00000093641
molybdenum cofactor sulfurase
chr9_-_104700609 2.76 ENSRNOT00000081815
ENSRNOT00000018503
solute carrier organic anion transporter family, member 6c1
chr6_-_86223052 2.74 ENSRNOT00000046828
fibrous sheath CABYR binding protein
chr2_+_180936688 2.74 ENSRNOT00000016039
acid sensing ion channel subunit family member 5
chr6_-_138536321 2.71 ENSRNOT00000077743

chrX_+_62282212 2.70 ENSRNOT00000039568

chr2_+_187951344 2.70 ENSRNOT00000027123
signal sequence receptor, beta
chr14_-_18839595 2.67 ENSRNOT00000078746
chemokine (C-X-C motif) ligand 3
chr5_+_153976535 2.67 ENSRNOT00000030881
similar to RIKEN cDNA 1700029M20
chr1_+_203509731 2.66 ENSRNOT00000028007
H6 family homeobox 3
chr10_+_89286047 2.65 ENSRNOT00000085831
glucose-6-phosphatase, catalytic subunit
chr1_+_80973739 2.65 ENSRNOT00000026088
ENSRNOT00000081983

chr6_-_139973811 2.65 ENSRNOT00000082875
immunoglobulin heavy variable 5-2
chr16_-_12662336 2.64 ENSRNOT00000080161
similar to hypothetical protein 4930474N05
chr4_-_50200328 2.60 ENSRNOT00000060530
aminoadipate-semialdehyde synthase
chr5_+_74766636 2.60 ENSRNOT00000030913

chr4_+_149261044 2.60 ENSRNOT00000066670
C-X-C motif chemokine ligand 12
chr6_-_27512287 2.60 ENSRNOT00000085937
ENSRNOT00000081278
ENSRNOT00000081323
selenoprotein I
chr2_-_243475639 2.59 ENSRNOT00000089222
similar to hypothetical protein DKFZp434G072
chr11_-_61530830 2.57 ENSRNOT00000059666
ENSRNOT00000068345
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr7_+_143092511 2.55 ENSRNOT00000084223
similar to RIKEN cDNA 1700011A15
chr16_-_7406951 2.55 ENSRNOT00000066508
dynein, axonemal, heavy chain 1
chr13_-_90641772 2.53 ENSRNOT00000064601
ATPase Na+/K+ transporting subunit alpha 4
chrX_-_63999622 2.52 ENSRNOT00000090902
protein gar2-like
chr9_-_50820290 2.49 ENSRNOT00000050748
uncharacterized LOC102548013
chr14_+_9555264 2.49 ENSRNOT00000002928
NK6 homeobox 1
chr9_+_100137881 2.46 ENSRNOT00000036328
G protein-coupled receptor 35
chr10_+_87774552 2.45 ENSRNOT00000044342
keratin associated protein 9-1
chr4_+_1470716 2.45 ENSRNOT00000044223
olfactory receptor 1235

Network of associatons between targets according to the STRING database.

First level regulatory network of Tcf7_Tcf7l2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.9 23.8 GO:0051977 lysophospholipid transport(GO:0051977)
5.7 17.1 GO:0001905 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
5.1 20.3 GO:0019483 beta-alanine biosynthetic process(GO:0019483)
3.6 10.9 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
3.6 36.0 GO:0018298 protein-chromophore linkage(GO:0018298)
3.6 10.8 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) multicellular organism lipid catabolic process(GO:0044240)
3.5 17.6 GO:0006548 histidine catabolic process(GO:0006548)
3.4 10.2 GO:0002254 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353) activation of plasma proteins involved in acute inflammatory response(GO:0002541)
3.3 13.2 GO:0042853 L-alanine catabolic process(GO:0042853)
2.6 10.5 GO:0014028 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) notochord formation(GO:0014028)
2.6 13.1 GO:0006526 arginine biosynthetic process(GO:0006526)
2.6 15.6 GO:0006572 tyrosine catabolic process(GO:0006572)
2.5 28.0 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
2.3 27.3 GO:0042159 lipoprotein catabolic process(GO:0042159)
2.2 6.5 GO:0071400 cellular response to oleic acid(GO:0071400)
1.9 7.6 GO:0002933 lipid hydroxylation(GO:0002933) alkaloid catabolic process(GO:0009822)
1.7 5.2 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
1.7 10.0 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
1.7 8.3 GO:0061113 pancreas morphogenesis(GO:0061113)
1.5 12.2 GO:0006776 vitamin A metabolic process(GO:0006776)
1.5 5.9 GO:0016098 monoterpenoid metabolic process(GO:0016098)
1.4 4.2 GO:0090172 microtubule cytoskeleton organization involved in homologous chromosome segregation(GO:0090172)
1.4 5.6 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.4 5.5 GO:0046351 disaccharide biosynthetic process(GO:0046351)
1.3 11.9 GO:0052697 xenobiotic glucuronidation(GO:0052697)
1.2 3.6 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
1.2 5.8 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
1.1 7.8 GO:0007290 spermatid nucleus elongation(GO:0007290)
1.1 4.4 GO:1903334 positive regulation of protein folding(GO:1903334)
1.0 3.1 GO:0070602 regulation of mismatch repair(GO:0032423) regulation of chondrocyte development(GO:0061181) regulation of centromeric sister chromatid cohesion(GO:0070602) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
1.0 8.3 GO:0042866 pyruvate biosynthetic process(GO:0042866)
1.0 6.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
1.0 17.7 GO:0046415 urate metabolic process(GO:0046415)
0.9 2.6 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.9 3.4 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.8 4.1 GO:0001757 somite specification(GO:0001757)
0.8 4.7 GO:0034059 response to anoxia(GO:0034059)
0.8 3.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.7 7.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.7 9.3 GO:0001778 plasma membrane repair(GO:0001778)
0.7 6.3 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.7 14.6 GO:0033327 Leydig cell differentiation(GO:0033327)
0.7 10.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.7 6.2 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.7 2.0 GO:0060266 negative regulation of NAD(P)H oxidase activity(GO:0033861) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.6 2.6 GO:1990478 response to ultrasound(GO:1990478)
0.6 1.8 GO:0010157 response to chlorate(GO:0010157)
0.6 2.3 GO:0021633 optic nerve structural organization(GO:0021633)
0.6 6.7 GO:0006108 malate metabolic process(GO:0006108)
0.5 2.7 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.5 7.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.5 3.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.5 1.5 GO:0060974 cell migration involved in heart formation(GO:0060974) regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.5 2.5 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.5 2.9 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.5 1.9 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.5 12.0 GO:0045793 positive regulation of cell size(GO:0045793)
0.5 9.9 GO:0042730 fibrinolysis(GO:0042730)
0.5 1.9 GO:1902741 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.5 4.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.4 2.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.4 2.2 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.4 3.4 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.4 8.5 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.4 3.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.4 1.2 GO:0002780 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
0.4 26.8 GO:0003341 cilium movement(GO:0003341)
0.4 1.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.4 1.1 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.4 12.5 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.4 1.5 GO:0001834 trophectodermal cell proliferation(GO:0001834) Cajal body organization(GO:0030576)
0.3 13.8 GO:0018149 peptide cross-linking(GO:0018149)
0.3 1.0 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.3 4.3 GO:0051546 keratinocyte migration(GO:0051546)
0.3 2.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.3 22.9 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.3 2.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.3 1.0 GO:0048749 compound eye development(GO:0048749)
0.3 2.8 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.3 2.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.3 3.1 GO:0048102 autophagic cell death(GO:0048102)
0.3 1.2 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.3 1.2 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.3 2.2 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.3 1.6 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.3 1.9 GO:0030035 microspike assembly(GO:0030035)
0.3 6.4 GO:0045109 intermediate filament organization(GO:0045109)
0.3 2.1 GO:0014029 neural crest formation(GO:0014029)
0.3 0.8 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.3 2.8 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.3 1.5 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.2 1.0 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.2 3.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.2 28.7 GO:0031638 zymogen activation(GO:0031638)
0.2 1.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 0.7 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.2 1.5 GO:0098792 xenophagy(GO:0098792)
0.2 2.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.2 1.9 GO:1904424 regulation of GTP binding(GO:1904424)
0.2 1.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 0.6 GO:0035938 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.2 1.3 GO:0070417 cellular response to cold(GO:0070417)
0.2 0.6 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 1.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 2.5 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.2 1.2 GO:0071000 response to magnetism(GO:0071000)
0.2 43.2 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.2 2.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.2 1.7 GO:0030259 lipid glycosylation(GO:0030259)
0.2 4.6 GO:0007340 acrosome reaction(GO:0007340)
0.2 3.2 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 0.4 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.1 0.6 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 1.4 GO:0007379 segment specification(GO:0007379)
0.1 6.9 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 7.7 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.1 2.5 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 0.8 GO:0019695 choline metabolic process(GO:0019695)
0.1 2.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 2.0 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.1 1.1 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.1 1.6 GO:0006544 glycine metabolic process(GO:0006544)
0.1 1.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.1 1.8 GO:0001675 acrosome assembly(GO:0001675)
0.1 1.6 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.3 GO:0044726 protection of DNA demethylation of female pronucleus(GO:0044726)
0.1 1.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.5 GO:0033227 dsRNA transport(GO:0033227)
0.1 2.0 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.1 0.5 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 6.6 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1 0.4 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 1.0 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 1.6 GO:0031295 T cell costimulation(GO:0031295)
0.1 0.4 GO:0070827 chromatin maintenance(GO:0070827)
0.1 0.3 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.3 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 1.7 GO:0009584 detection of visible light(GO:0009584)
0.1 1.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 3.8 GO:0015914 phospholipid transport(GO:0015914)
0.1 1.9 GO:0001569 patterning of blood vessels(GO:0001569)
0.1 1.9 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 0.9 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 2.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 2.7 GO:0007566 embryo implantation(GO:0007566)
0.1 1.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 1.3 GO:0045103 intermediate filament-based process(GO:0045103)
0.1 0.8 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 10.0 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.3 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.6 GO:0042407 cristae formation(GO:0042407)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) negative regulation of platelet aggregation(GO:0090331)
0.0 0.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.2 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.1 GO:0019086 late viral transcription(GO:0019086)
0.0 1.1 GO:0007413 axonal fasciculation(GO:0007413)
0.0 1.8 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 5.4 GO:0016485 protein processing(GO:0016485)
0.0 1.1 GO:0060292 long term synaptic depression(GO:0060292)
0.0 1.1 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.4 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 2.4 GO:0060349 bone morphogenesis(GO:0060349)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 1.1 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 1.5 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.6 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.8 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 2.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.9 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 1.3 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.4 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.9 GO:0006414 translational elongation(GO:0006414)
0.0 0.4 GO:0007031 peroxisome organization(GO:0007031)
0.0 14.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 16.6 GO:0005879 axonemal microtubule(GO:0005879)
1.5 4.6 GO:0005960 glycine cleavage complex(GO:0005960)
1.4 10.0 GO:0005579 membrane attack complex(GO:0005579)
1.4 14.0 GO:0045179 apical cortex(GO:0045179)
1.2 4.9 GO:0036156 inner dynein arm(GO:0036156)
1.0 9.3 GO:0005826 actomyosin contractile ring(GO:0005826)
1.0 126.0 GO:0072562 blood microparticle(GO:0072562)
0.9 4.7 GO:0072557 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.9 6.5 GO:0005858 axonemal dynein complex(GO:0005858)
0.9 6.1 GO:0031415 NatA complex(GO:0031415)
0.7 17.4 GO:0001533 cornified envelope(GO:0001533)
0.6 4.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.6 4.1 GO:1990357 terminal web(GO:1990357)
0.5 15.9 GO:0097228 sperm principal piece(GO:0097228)
0.5 2.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.5 1.5 GO:1990826 nucleoplasmic periphery of the nuclear pore complex(GO:1990826)
0.5 2.9 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.5 8.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.4 30.0 GO:0045095 keratin filament(GO:0045095)
0.4 7.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.4 4.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.4 2.2 GO:0071547 piP-body(GO:0071547)
0.3 3.1 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.3 8.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.3 12.2 GO:0005771 multivesicular body(GO:0005771)
0.3 0.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3 1.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.3 0.8 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.3 1.3 GO:0070552 BRISC complex(GO:0070552)
0.3 3.1 GO:0043202 lysosomal lumen(GO:0043202)
0.3 18.7 GO:0005882 intermediate filament(GO:0005882)
0.2 3.5 GO:0045180 basal cortex(GO:0045180)
0.2 1.5 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.2 2.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 3.8 GO:0005614 interstitial matrix(GO:0005614)
0.2 12.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 0.5 GO:0061574 ASAP complex(GO:0061574)
0.2 3.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 1.5 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 2.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.1 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.4 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 1.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 2.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 12.6 GO:0036064 ciliary basal body(GO:0036064)
0.1 2.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 2.0 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.1 4.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 3.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 1.3 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.6 GO:0061617 MICOS complex(GO:0061617)
0.1 1.8 GO:0002080 acrosomal membrane(GO:0002080)
0.1 10.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 0.3 GO:0032044 DSIF complex(GO:0032044)
0.1 109.5 GO:0005615 extracellular space(GO:0005615)
0.1 0.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 3.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 2.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 1.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 5.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 2.0 GO:0002102 podosome(GO:0002102)
0.0 4.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.4 GO:0031597 proteasome regulatory particle, lid subcomplex(GO:0008541) cytosolic proteasome complex(GO:0031597)
0.0 0.7 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 1.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 2.8 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 2.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 2.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 5.4 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.0 GO:0016363 nuclear matrix(GO:0016363)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
9.3 28.0 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
9.0 27.1 GO:0031714 C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
7.2 36.0 GO:0019862 IgA binding(GO:0019862)
5.2 15.6 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
4.4 13.2 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
3.8 11.3 GO:0004159 dihydrouracil dehydrogenase (NAD+) activity(GO:0004159) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
3.3 13.1 GO:0034618 arginine binding(GO:0034618)
2.3 14.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
2.2 37.9 GO:0001972 retinoic acid binding(GO:0001972)
2.1 6.3 GO:0032810 sterol response element binding(GO:0032810)
2.1 8.3 GO:0004743 pyruvate kinase activity(GO:0004743)
1.7 5.2 GO:0004370 glycerol kinase activity(GO:0004370)
1.7 5.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
1.7 6.7 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
1.7 8.3 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
1.6 9.8 GO:0015245 fatty acid transporter activity(GO:0015245)
1.6 6.5 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
1.5 10.8 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
1.4 8.7 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
1.3 6.6 GO:0004103 choline kinase activity(GO:0004103)
1.3 3.8 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
1.2 3.6 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
1.1 3.4 GO:0030156 benzodiazepine receptor binding(GO:0030156)
1.0 5.8 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
1.0 4.8 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.9 16.1 GO:0043295 glutathione binding(GO:0043295)
0.8 11.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.8 9.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.7 2.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.7 2.8 GO:0008265 Mo-molybdopterin cofactor sulfurase activity(GO:0008265)
0.7 3.4 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.7 7.5 GO:0001846 opsonin binding(GO:0001846)
0.6 8.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.6 62.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.5 2.7 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.5 3.7 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.5 21.1 GO:0070330 aromatase activity(GO:0070330)
0.5 2.0 GO:0042806 fucose binding(GO:0042806)
0.5 2.0 GO:0036132 13-prostaglandin reductase activity(GO:0036132)
0.5 2.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.5 2.8 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.4 6.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.4 13.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.4 1.7 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.4 3.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.4 3.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.4 2.0 GO:0001155 TFIIIA-class transcription factor binding(GO:0001155)
0.4 1.2 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.4 1.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.4 10.0 GO:0004950 chemokine receptor activity(GO:0004950)
0.4 2.2 GO:0004568 chitinase activity(GO:0004568)
0.4 4.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.4 1.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.4 9.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.3 17.6 GO:0016836 hydro-lyase activity(GO:0016836)
0.3 3.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.3 7.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.3 2.2 GO:1901612 cardiolipin binding(GO:1901612)
0.3 68.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.3 4.0 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.3 1.5 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.3 0.9 GO:0004522 ribonuclease A activity(GO:0004522)
0.3 7.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.3 3.1 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.3 2.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.3 0.8 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.3 6.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3 0.8 GO:0004104 acetylcholinesterase activity(GO:0003990) cholinesterase activity(GO:0004104)
0.3 2.3 GO:0034056 estrogen response element binding(GO:0034056)
0.3 0.8 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.2 1.1 GO:0005042 netrin receptor activity(GO:0005042)
0.2 3.8 GO:0015248 sterol transporter activity(GO:0015248)
0.2 8.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 1.2 GO:0070878 primary miRNA binding(GO:0070878)
0.2 1.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.2 2.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 2.0 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.2 4.2 GO:0070840 dynein complex binding(GO:0070840)
0.2 9.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.2 1.0 GO:0070411 I-SMAD binding(GO:0070411)
0.2 9.4 GO:0019894 kinesin binding(GO:0019894)
0.2 14.8 GO:0003777 microtubule motor activity(GO:0003777)
0.2 3.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 2.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 4.6 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.2 10.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 2.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.7 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 1.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.2 GO:0071253 connexin binding(GO:0071253)
0.1 22.5 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.1 0.6 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 2.6 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 2.0 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 5.4 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 4.4 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 4.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 14.3 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 3.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.3 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.8 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.1 1.6 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.6 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 7.0 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.1 0.5 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 2.0 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 1.5 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 0.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 4.3 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.1 3.6 GO:0051018 protein kinase A binding(GO:0051018)
0.1 2.0 GO:0042923 neuropeptide binding(GO:0042923)
0.1 0.7 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 1.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 1.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 2.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.9 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 1.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 5.8 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 4.2 GO:0005179 hormone activity(GO:0005179)
0.0 20.2 GO:0005198 structural molecule activity(GO:0005198)
0.0 5.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.9 GO:0005518 collagen binding(GO:0005518)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.5 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.7 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 1.2 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 14.5 GO:0004984 olfactory receptor activity(GO:0004984)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 14.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.7 37.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.5 12.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.5 109.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3 6.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.3 11.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.2 5.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.2 12.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 4.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 8.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 2.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 5.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 42.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
2.3 28.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
1.6 20.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
1.3 17.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
1.1 11.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.9 1.8 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.8 17.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.7 13.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.6 24.9 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.6 11.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.6 10.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.5 16.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.5 6.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.3 9.6 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.3 10.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.2 12.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 5.7 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.2 31.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.2 1.3 REACTOME DEFENSINS Genes involved in Defensins
0.2 2.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 5.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 6.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 3.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 2.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 6.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 4.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1 1.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 2.1 REACTOME KINESINS Genes involved in Kinesins
0.1 7.3 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.1 2.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 7.5 REACTOME TRANSLATION Genes involved in Translation
0.0 2.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 7.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.2 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 2.0 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 2.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing