ISMARA results: Tcf4

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Tcf4_Mesp1

Z-value: 2.15

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Transcription factors associated with Tcf4_Mesp1

Gene Symbol	Gene ID	Gene Info
Tcf4 NCBI RGD Ensembl	ENSRNOG00000012405	transcription factor 4
Mesp1 NCBI RGD Ensembl	ENSRNOG00000014951	mesoderm posterior bHLH transcription factor 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Tcf4	rn6_v1_chr18_+_65155685_65155685	-0.45	5.2e-17	Click!
Mesp1	rn6_v1_chr1_-_141533908_141533908	0.20	3.5e-04	Click!

Activity profile of Tcf4_Mesp1 motif

Sorted Z-values of Tcf4_Mesp1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr10_-_31359699 Show fit	99.07	ENSRNOT00000081280	Cyfip2 NCBI RGD Ensembl Show fit	cytoplasmic FMR1 interacting protein 2
chr3_-_7141522 Show fit	67.80	ENSRNOT00000014572	Cel NCBI RGD Ensembl Show fit	carboxyl ester lipase
chr2_-_105089659 Show fit	65.57	ENSRNOT00000043381	Cpb1 NCBI RGD Ensembl Show fit	carboxypeptidase B1
chr9_+_82053581 Show fit	60.71	ENSRNOT00000086375	Wnt10a NCBI RGD Ensembl Show fit	wingless-type MMTV integration site family, member 10A
chr1_-_227441442 Show fit	58.01	ENSRNOT00000028433	Ms4a1 NCBI RGD Ensembl Show fit	membrane spanning 4-domains A1
chr16_+_54765325 Show fit	55.17	ENSRNOT00000065327 ENSRNOT00000086899	Mtmr7 NCBI RGD Ensembl Show fit	myotubularin related protein 7
chr19_-_37907714 Show fit	53.03	ENSRNOT00000026361	Ctrl NCBI RGD Ensembl Show fit	chymotrypsin-like
chr1_+_100199057 Show fit	50.47	ENSRNOT00000025831	Klk1 NCBI RGD Ensembl Show fit	kallikrein 1
chr10_-_31419235 Show fit	48.43	ENSRNOT00000059496	Cyfip2 NCBI RGD Ensembl Show fit	cytoplasmic FMR1 interacting protein 2
chr5_+_154522119 Show fit	48.35	ENSRNOT00000072618	E2f2 NCBI RGD Ensembl Show fit	E2F transcription factor 2
chr3_-_16999720 Show fit	48.24	ENSRNOT00000074382	RGD1563231 NCBI RGD Ensembl Show fit	similar to immunoglobulin kappa-chain VK-1
chr6_-_140407307 Show fit	45.28	ENSRNOT00000079087	AABR07065768.3 NCBI RGD Ensembl Show fit
chr6_-_141488290 Show fit	44.71	ENSRNOT00000067336	AABR07065792.1 NCBI RGD Ensembl Show fit
chr9_-_14668297 Show fit	43.92	ENSRNOT00000042404	Treml2 NCBI RGD Ensembl Show fit	triggering receptor expressed on myeloid cells-like 2
chr18_+_70427007 Show fit	42.09	ENSRNOT00000087959 ENSRNOT00000019512	Myo5b NCBI RGD Ensembl Show fit	myosin Vb
chr15_-_37383277 Show fit	42.05	ENSRNOT00000011711	Gjb2 NCBI RGD Ensembl Show fit	gap junction protein, beta 2
chr4_+_70755795 Show fit	41.20	ENSRNOT00000043527	LOC683849 NCBI RGD Ensembl Show fit	similar to Anionic trypsin II precursor (Pretrypsinogen II)
chr4_+_98370797 Show fit	40.94	ENSRNOT00000031991	AABR07060872.1 NCBI RGD Ensembl Show fit
chr7_-_107634287 Show fit	40.50	ENSRNOT00000093672 ENSRNOT00000087116	Sla NCBI RGD Ensembl Show fit	src-like adaptor
chr10_+_87774552 Show fit	40.04	ENSRNOT00000044342	Krtap9-1 NCBI RGD Ensembl Show fit	keratin associated protein 9-1
chr4_+_70689737 Show fit	40.03	ENSRNOT00000018852	Prss2 NCBI RGD Ensembl Show fit	protease, serine, 2
chr6_-_138508753 Show fit	38.74	ENSRNOT00000006888	Ighm NCBI RGD Ensembl Show fit	immunoglobulin heavy constant mu
chr7_-_11330278 Show fit	38.68	ENSRNOT00000027730	Matk NCBI RGD Ensembl Show fit	megakaryocyte-associated tyrosine kinase
chr17_-_8619737 Show fit	37.87	ENSRNOT00000065217	RGD1562024 NCBI RGD Ensembl Show fit	RGD1562024
chr9_-_54457753 Show fit	36.64	ENSRNOT00000020032	Stat1 NCBI RGD Ensembl Show fit	signal transducer and activator of transcription 1
chr6_-_138679665 Show fit	36.55	ENSRNOT00000086777	AABR07065651.4 NCBI RGD Ensembl Show fit
chr15_-_37410848 Show fit	35.57	ENSRNOT00000081757	Gjb6 NCBI RGD Ensembl Show fit	gap junction protein, beta 6
chr3_+_16846412 Show fit	35.40	ENSRNOT00000074266	AABR07051551.1 NCBI RGD Ensembl Show fit
chr6_-_139041812 Show fit	35.26	ENSRNOT00000074510	AABR07065656.1 NCBI RGD Ensembl Show fit
chr4_+_56981283 Show fit	35.01	ENSRNOT00000010989	Tspan33 NCBI RGD Ensembl Show fit	tetraspanin 33
chr1_-_214202853 Show fit	34.76	ENSRNOT00000022954	Lmntd2 NCBI RGD Ensembl Show fit	lamin tail domain containing 2
chr10_+_84309430 Show fit	34.07	ENSRNOT00000030159	Skap1 NCBI RGD Ensembl Show fit	src kinase associated phosphoprotein 1
chr16_+_74865516 Show fit	33.74	ENSRNOT00000058072	Atp7b NCBI RGD Ensembl Show fit	ATPase copper transporting beta
chr8_+_55603968 Show fit	33.47	ENSRNOT00000066848	Pou2af1 NCBI RGD Ensembl Show fit	POU class 2 associating factor 1
chr6_+_139158334 Show fit	33.37	ENSRNOT00000089227	AABR07065673.1 NCBI RGD Ensembl Show fit
chr10_+_87759769 Show fit	32.75	ENSRNOT00000017378 ENSRNOT00000046526	Krtap9-1 NCBI RGD Ensembl Show fit	keratin associated protein 9-1
chr6_-_138909105 Show fit	32.61	ENSRNOT00000087855	AABR07065656.9 NCBI RGD Ensembl Show fit
chr6_-_139041654 Show fit	32.56	ENSRNOT00000075664	AABR07065656.1 NCBI RGD Ensembl Show fit
chr6_-_138772736 Show fit	32.40	ENSRNOT00000071492	AABR07065651.1 NCBI RGD Ensembl Show fit
chr6_-_140572023 Show fit	31.70	ENSRNOT00000072338	AABR07065772.1 NCBI RGD Ensembl Show fit
chr16_-_39970532 Show fit	31.59	ENSRNOT00000071331	Spata4 NCBI RGD Ensembl Show fit	spermatogenesis associated 4
chr11_+_88424414 Show fit	30.90	ENSRNOT00000022328	Spag6l NCBI RGD Ensembl Show fit	sperm associated antigen 6-like
chr1_-_197821936 Show fit	30.86	ENSRNOT00000055027	Cd19 NCBI RGD Ensembl Show fit	CD19 molecule
chr1_-_53087474 Show fit	30.81	ENSRNOT00000017302	Ccr6 NCBI RGD Ensembl Show fit	C-C motif chemokine receptor 6
chr4_-_69268336 Show fit	30.75	ENSRNOT00000018042	Prss3b NCBI RGD Ensembl Show fit	protease, serine, 3B
chr1_-_165680176 Show fit	30.62	ENSRNOT00000025245 ENSRNOT00000082697	Plekhb1 NCBI RGD Ensembl Show fit	pleckstrin homology domain containing B1
chr12_-_32740732 Show fit	30.50	ENSRNOT00000064526	Glt1d1 NCBI RGD Ensembl Show fit	glycosyltransferase 1 domain containing 1
chr6_+_72359791 Show fit	30.46	ENSRNOT00000007365	Coch NCBI RGD Ensembl Show fit	cochlin
chr3_-_16441030 Show fit	30.45	ENSRNOT00000047784	AABR07051532.1 NCBI RGD Ensembl Show fit
chr6_-_138536162 Show fit	30.31	ENSRNOT00000083031	AABR07065643.1 NCBI RGD Ensembl Show fit
chr6_-_138093643 Show fit	30.13	ENSRNOT00000045874	Igh-6 NCBI RGD Ensembl Show fit	immunoglobulin heavy chain 6
chr6_+_139551751 Show fit	29.98	ENSRNOT00000081684	AABR07065699.2 NCBI RGD Ensembl Show fit
chr10_-_70220558 Show fit	29.29	ENSRNOT00000041389 ENSRNOT00000076398 ENSRNOT00000076596	Rffl NCBI RGD Ensembl Show fit	ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr2_+_174013288 Show fit	29.20	ENSRNOT00000013904	Serpini1 NCBI RGD Ensembl Show fit	serpin family I member 1
chr19_-_43596801 Show fit	28.79	ENSRNOT00000025625	Fa2h NCBI RGD Ensembl Show fit	fatty acid 2-hydroxylase
chr1_+_279798187 Show fit	28.69	ENSRNOT00000024065	Pnlip NCBI RGD Ensembl Show fit	pancreatic lipase
chr6_-_142635763 Show fit	28.66	ENSRNOT00000048908	AABR07065815.2 NCBI RGD Ensembl Show fit
chr6_-_138565404 Show fit	28.31	ENSRNOT00000079420	AABR07065645.2 NCBI RGD Ensembl Show fit
chr17_-_417480 Show fit	28.12	ENSRNOT00000023685	Fbp1 NCBI RGD Ensembl Show fit	fructose-bisphosphatase 1
chr3_+_141927400 Show fit	27.97	ENSRNOT00000066588	AABR07054117.1 NCBI RGD Ensembl Show fit
chr4_-_70628470 Show fit	27.69	ENSRNOT00000029319	Try5 NCBI RGD Ensembl Show fit	trypsin 5
chr1_+_154377447 Show fit	27.46	ENSRNOT00000084268 ENSRNOT00000092086 ENSRNOT00000091470 ENSRNOT00000025415	Picalm NCBI RGD Ensembl Show fit	phosphatidylinositol binding clathrin assembly protein
chr3_-_16537433 Show fit	26.79	ENSRNOT00000048523	AABR07051533.2 NCBI RGD Ensembl Show fit
chr13_+_111870121 Show fit	26.78	ENSRNOT00000007333	Irf6 NCBI RGD Ensembl Show fit	interferon regulatory factor 6
chr4_-_67206426 Show fit	26.70	ENSRNOT00000013124	Mkrn1 NCBI RGD Ensembl Show fit	makorin ring finger protein 1
chr6_-_138948583 Show fit	26.50	ENSRNOT00000084614	AABR07065656.2 NCBI RGD Ensembl Show fit
chr6_-_141291347 Show fit	26.43	ENSRNOT00000008333	AABR07065789.1 NCBI RGD Ensembl Show fit
chr10_+_11912543 Show fit	26.34	ENSRNOT00000045192	Zfp597 NCBI RGD Ensembl Show fit	zinc finger protein 597
chr16_+_6078122 Show fit	26.21	ENSRNOT00000021407	Chdh NCBI RGD Ensembl Show fit	choline dehydrogenase
chr2_-_164684985 Show fit	26.13	ENSRNOT00000057504	Rarres1 NCBI RGD Ensembl Show fit	retinoic acid receptor responder 1
chr3_+_16610086 Show fit	26.09	ENSRNOT00000046231	LOC100361009 NCBI RGD Ensembl Show fit	rCG64257-like
chr10_+_14122878 Show fit	26.08	ENSRNOT00000052008	Hs3st6 NCBI RGD Ensembl Show fit	heparan sulfate-glucosamine 3-sulfotransferase 6
chr1_-_87155118 Show fit	25.89	ENSRNOT00000072441	AABR07002854.1 NCBI RGD Ensembl Show fit
chr6_-_138536321 Show fit	25.48	ENSRNOT00000077743	AABR07065643.1 NCBI RGD Ensembl Show fit
chr6_+_139523495 Show fit	25.38	ENSRNOT00000075467	AABR07065699.4 NCBI RGD Ensembl Show fit
chr6_-_138948424 Show fit	25.23	ENSRNOT00000072566	AABR07065656.2 NCBI RGD Ensembl Show fit
chr6_-_102196138 Show fit	25.04	ENSRNOT00000014132	Tmem229b NCBI RGD Ensembl Show fit	transmembrane protein 229B
chr8_-_62616828 Show fit	24.85	ENSRNOT00000068340	Arid3b NCBI RGD Ensembl Show fit	AT-rich interaction domain 3B
chr6_-_139719323 Show fit	24.81	ENSRNOT00000090133	AABR07065705.4 NCBI RGD Ensembl Show fit
chr13_-_42263024 Show fit	24.79	ENSRNOT00000004741	Lypd1 NCBI RGD Ensembl Show fit	Ly6/Plaur domain containing 1
chr1_-_20155960 Show fit	24.60	ENSRNOT00000061389	Samd3 NCBI RGD Ensembl Show fit	sterile alpha motif domain containing 3
chr9_-_85445939 Show fit	24.56	ENSRNOT00000072160	Ap1s3 NCBI RGD Ensembl Show fit	adaptor-related protein complex 1, sigma 3 subunit
chr4_+_57952982 Show fit	24.51	ENSRNOT00000014465	Cpa1 NCBI RGD Ensembl Show fit	carboxypeptidase A1
chr6_-_139747737 Show fit	24.47	ENSRNOT00000090626	AABR07065705.3 NCBI RGD Ensembl Show fit
chr6_-_139997537 Show fit	24.36	ENSRNOT00000073207	AABR07065740.1 NCBI RGD Ensembl Show fit
chr6_-_138679506 Show fit	24.24	ENSRNOT00000075376	AABR07065651.4 NCBI RGD Ensembl Show fit
chr3_+_16413080 Show fit	24.22	ENSRNOT00000040386	LOC100912707 NCBI RGD Ensembl Show fit	Ig kappa chain V19-17-like
chrX_+_157150655 Show fit	24.03	ENSRNOT00000090795	Pnck NCBI RGD Ensembl Show fit	pregnancy up-regulated nonubiquitous CaM kinase
chr9_+_40972089 Show fit	23.95	ENSRNOT00000067928	Ptpn18 NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, non-receptor type 18
chr6_-_140418831 Show fit	23.93	ENSRNOT00000086301	AABR07065768.2 NCBI RGD Ensembl Show fit
chr4_+_127164453 Show fit	23.61	ENSRNOT00000017889	Kbtbd8 NCBI RGD Ensembl Show fit	kelch repeat and BTB domain containing 8
chr10_+_87782376 Show fit	23.16	ENSRNOT00000017415	LOC680396 NCBI RGD Ensembl Show fit	hypothetical protein LOC680396
chr1_+_207654487 Show fit	22.92	ENSRNOT00000025569	Foxi2 NCBI RGD Ensembl Show fit	forkhead box I2
chr5_-_153924896 Show fit	22.86	ENSRNOT00000065247	Grhl3 NCBI RGD Ensembl Show fit	grainyhead-like transcription factor 3
chr6_+_139209936 Show fit	22.60	ENSRNOT00000087620	AABR07065680.1 NCBI RGD Ensembl Show fit
chr6_-_138744480 Show fit	22.56	ENSRNOT00000089387	AABR07065651.5 NCBI RGD Ensembl Show fit
chr4_+_33638709 Show fit	22.53	ENSRNOT00000009888 ENSRNOT00000034719 ENSRNOT00000052333	Tac1 NCBI RGD Ensembl Show fit	tachykinin, precursor 1
chr3_+_111545007 Show fit	22.49	ENSRNOT00000007247	Itpka NCBI RGD Ensembl Show fit	inositol-trisphosphate 3-kinase A
chr1_-_98501249 Show fit	22.45	ENSRNOT00000023858	Lim2 NCBI RGD Ensembl Show fit	lens intrinsic membrane protein 2
chr6_-_139654508 Show fit	22.08	ENSRNOT00000082576	AABR07065705.5 NCBI RGD Ensembl Show fit
chr19_-_462559 Show fit	22.01	ENSRNOT00000046676	AABR07042633.1 NCBI RGD Ensembl Show fit
chr9_-_9985358 Show fit	21.97	ENSRNOT00000080856	Crb3 NCBI RGD Ensembl Show fit	crumbs 3, cell polarity complex component
chr7_-_122963299 Show fit	21.91	ENSRNOT00000090208	Rangap1 NCBI RGD Ensembl Show fit	RAN GTPase activating protein 1
chr13_-_44345735 Show fit	21.90	ENSRNOT00000005006	Tmem163 NCBI RGD Ensembl Show fit	transmembrane protein 163
chr8_-_49280901 Show fit	21.77	ENSRNOT00000021390	Cd3g NCBI RGD Ensembl Show fit	CD3g molecule
chr2_-_30577218 Show fit	21.73	ENSRNOT00000024674	Ocln NCBI RGD Ensembl Show fit	occludin
chr16_-_15798974 Show fit	21.69	ENSRNOT00000046842 ENSRNOT00000065946	Nrg3 NCBI RGD Ensembl Show fit	neuregulin 3
chr5_+_114940053 Show fit	21.28	ENSRNOT00000012396	Hook1 NCBI RGD Ensembl Show fit	hook microtubule-tethering protein 1
chr6_-_99783047 Show fit	21.25	ENSRNOT00000009028	Sptb NCBI RGD Ensembl Show fit	spectrin, beta, erythrocytic
chr6_-_138852571 Show fit	21.20	ENSRNOT00000081803	AABR07065656.8 NCBI RGD Ensembl Show fit
chr2_-_30576591 Show fit	20.59	ENSRNOT00000084667	Ocln NCBI RGD Ensembl Show fit	occludin
chr6_+_139523337 Show fit	20.42	ENSRNOT00000090711	AABR07065699.4 NCBI RGD Ensembl Show fit
chr6_-_125027553 Show fit	20.41	ENSRNOT00000005908	Ccdc88c NCBI RGD Ensembl Show fit	coiled-coil domain containing 88C
chr20_+_40618128 Show fit	20.34	ENSRNOT00000001075 ENSRNOT00000057364	Pkib NCBI RGD Ensembl Show fit	cAMP-dependent protein kinase inhibitor beta
chr4_-_122237754 Show fit	20.27	ENSRNOT00000029915	Chst13 NCBI RGD Ensembl Show fit	carbohydrate sulfotransferase 13
chr19_+_24545318 Show fit	20.15	ENSRNOT00000005071	Clgn NCBI RGD Ensembl Show fit	calmegin
chr8_-_13513337 Show fit	20.14	ENSRNOT00000071532	LOC108348070 NCBI RGD Ensembl Show fit	lysine-specific demethylase 4D
chr1_-_280233929 Show fit	20.11	ENSRNOT00000085778	Shtn1 NCBI RGD Ensembl Show fit	shootin 1
chr13_-_51076165 Show fit	20.03	ENSRNOT00000004602	Adora1 NCBI RGD Ensembl Show fit	adenosine A1 receptor
chr10_+_91254058 Show fit	19.92	ENSRNOT00000087218 ENSRNOT00000065373	Fmnl1 NCBI RGD Ensembl Show fit	formin-like 1
chr7_-_143317674 Show fit	19.87	ENSRNOT00000080010	Krt5 NCBI RGD Ensembl Show fit	keratin 5
chr6_-_140715174 Show fit	19.75	ENSRNOT00000085345	AABR07065773.1 NCBI RGD Ensembl Show fit
chr19_+_38768467 Show fit	19.71	ENSRNOT00000027346	Cdh1 NCBI RGD Ensembl Show fit	cadherin 1
chr14_-_18853315 Show fit	19.67	ENSRNOT00000003794	Ppbp NCBI RGD Ensembl Show fit	pro-platelet basic protein
chr6_+_139412169 Show fit	19.65	ENSRNOT00000080187	AABR07065693.1 NCBI RGD Ensembl Show fit
chr4_-_70747226 Show fit	19.60	ENSRNOT00000044960	LOC102554637 NCBI RGD Ensembl Show fit	anionic trypsin-2-like
chr3_-_168033457 Show fit	19.51	ENSRNOT00000055111	Bcas1 NCBI RGD Ensembl Show fit	breast carcinoma amplified sequence 1
chr1_-_37726151 Show fit	19.50	ENSRNOT00000071842	RGD1308544 NCBI RGD Ensembl Show fit	LOC361192
chr8_-_50539331 Show fit	19.48	ENSRNOT00000088997	AABR07073400.1 NCBI RGD Ensembl Show fit
chr5_-_58987760 Show fit	19.45	ENSRNOT00000035040	Sit1 NCBI RGD Ensembl Show fit	signaling threshold regulating transmembrane adaptor 1
chr15_-_80713153 Show fit	19.17	ENSRNOT00000063800	Klhl1 NCBI RGD Ensembl Show fit	kelch-like family member 1
chr1_-_222118459 Show fit	19.08	ENSRNOT00000067217	Ccdc88b NCBI RGD Ensembl Show fit	coiled-coil domain containing 88B
chr4_+_99185885 Show fit	19.03	ENSRNOT00000009392	Cd8b NCBI RGD Ensembl Show fit	CD8b molecule
chr15_-_42947656 Show fit	19.03	ENSRNOT00000030007	Ptk2b NCBI RGD Ensembl Show fit	protein tyrosine kinase 2 beta
chr2_-_202816562 Show fit	18.98	ENSRNOT00000020401	Fam46c NCBI RGD Ensembl Show fit	family with sequence similarity 46, member C
chr4_+_98481520 Show fit	18.94	ENSRNOT00000078381 ENSRNOT00000048493	AABR07060886.1 NCBI RGD Ensembl Show fit
chr4_-_95970666 Show fit	18.93	ENSRNOT00000008826	Hpgds NCBI RGD Ensembl Show fit	hematopoietic prostaglandin D synthase
chr4_-_68597586 Show fit	18.89	ENSRNOT00000015921	RGD1563986 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA E330009J07 gene
chr9_+_10172832 Show fit	18.89	ENSRNOT00000074555	Acsbg2 NCBI RGD Ensembl Show fit	acyl-CoA synthetase bubblegum family member 2
chr18_+_60392376 Show fit	18.88	ENSRNOT00000023890	Nedd4l NCBI RGD Ensembl Show fit	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr18_+_25962855 Show fit	18.79	ENSRNOT00000078822	Camk4 NCBI RGD Ensembl Show fit	calcium/calmodulin-dependent protein kinase IV
chr5_+_48274477 Show fit	18.74	ENSRNOT00000075992 ENSRNOT00000041271	Ube2j1 NCBI RGD Ensembl Show fit	ubiquitin-conjugating enzyme E2, J1
chr1_+_255040426 Show fit	18.71	ENSRNOT00000092151	Pcgf5 NCBI RGD Ensembl Show fit	polycomb group ring finger 5
chr6_-_138565245 Show fit	18.70	ENSRNOT00000070980	AABR07065645.2 NCBI RGD Ensembl Show fit
chr6_+_139177200 Show fit	18.68	ENSRNOT00000084131	AABR07065676.1 NCBI RGD Ensembl Show fit
chr17_+_44556039 Show fit	18.68	ENSRNOT00000086540	Prss16 NCBI RGD Ensembl Show fit	protease, serine 16
chr1_-_197770669 Show fit	18.65	ENSRNOT00000023563	Lat NCBI RGD Ensembl Show fit	linker for activation of T cells
chr10_-_90312386 Show fit	18.61	ENSRNOT00000028445	Slc4a1 NCBI RGD Ensembl Show fit	solute carrier family 4 member 1
chr16_+_20027348 Show fit	18.57	ENSRNOT00000034589	Fam129c NCBI RGD Ensembl Show fit	family with sequence similarity 129, member C
chr1_-_142020525 Show fit	18.53	ENSRNOT00000042558	Cib1 NCBI RGD Ensembl Show fit	calcium and integrin binding 1
chr3_-_12415073 Show fit	18.49	ENSRNOT00000022755	Ralgps1 NCBI RGD Ensembl Show fit	Ral GEF with PH domain and SH3 binding motif 1
chr2_-_139528162 Show fit	18.23	ENSRNOT00000014317	Slc7a11 NCBI RGD Ensembl Show fit	solute carrier family 7 member 11
chr17_+_85382116 Show fit	18.15	ENSRNOT00000002513	Spag6 NCBI RGD Ensembl Show fit	sperm associated antigen 6
chr6_-_138640187 Show fit	18.13	ENSRNOT00000087983	AABR07065651.6 NCBI RGD Ensembl Show fit
chr3_+_92640752 Show fit	17.87	ENSRNOT00000007604	Slc1a2 NCBI RGD Ensembl Show fit	solute carrier family 1 member 2
chr19_-_58735173 Show fit	17.79	ENSRNOT00000030077	Pcnx2 NCBI RGD Ensembl Show fit	pecanex homolog 2 (Drosophila)
chr5_-_127273656 Show fit	17.77	ENSRNOT00000057341	Dmrtb1 NCBI RGD Ensembl Show fit	DMRT-like family B with proline-rich C-terminal, 1
chr4_-_69163881 Show fit	17.74	ENSRNOT00000048779	Tryx5 NCBI RGD Ensembl Show fit	trypsin X5
chr6_-_138772894 Show fit	17.68	ENSRNOT00000080779	AABR07065651.1 NCBI RGD Ensembl Show fit
chr18_+_31094965 Show fit	17.59	ENSRNOT00000026526	Rell2 NCBI RGD Ensembl Show fit	RELT-like 2
chr10_-_70735742 Show fit	17.44	ENSRNOT00000077035	Heatr9 NCBI RGD Ensembl Show fit	HEAT repeat containing 9
chr1_+_193424812 Show fit	17.36	ENSRNOT00000019939	Aqp8 NCBI RGD Ensembl Show fit	aquaporin 8
chr4_-_122741110 Show fit	17.32	ENSRNOT00000008888	Nup210 NCBI RGD Ensembl Show fit	nucleoporin 210
chr7_-_119768082 Show fit	17.29	ENSRNOT00000009612	Sstr3 NCBI RGD Ensembl Show fit	somatostatin receptor 3
chr6_+_139486775 Show fit	17.29	ENSRNOT00000077771	AABR07065699.3 NCBI RGD Ensembl Show fit
chr19_-_26053762 Show fit	17.23	ENSRNOT00000004646	MAST1 NCBI RGD Ensembl Show fit	microtubule associated serine/threonine kinase 1
chr13_-_76049363 Show fit	17.21	ENSRNOT00000075865 ENSRNOT00000007455	Brinp2 NCBI RGD Ensembl Show fit	BMP/retinoic acid inducible neural specific 2
chr6_-_131914028 Show fit	17.14	ENSRNOT00000007602	Bcl11b NCBI RGD Ensembl Show fit	B-cell CLL/lymphoma 11B
chr11_+_66878658 Show fit	17.04	ENSRNOT00000003208	Eaf2 NCBI RGD Ensembl Show fit	ELL associated factor 2
chr20_-_50564987 Show fit	16.96	ENSRNOT00000034485 ENSRNOT00000064466	Lin28b NCBI RGD Ensembl Show fit	lin-28 homolog B
chr10_-_87564327 Show fit	16.90	ENSRNOT00000064760 ENSRNOT00000068237	LOC680160 NCBI RGD Ensembl Show fit	similar to keratin associated protein 4-7
chr4_+_176994129 Show fit	16.88	ENSRNOT00000018734	Cmas NCBI RGD Ensembl Show fit	cytidine monophosphate N-acetylneuraminic acid synthetase
chr20_-_4863011 Show fit	16.83	ENSRNOT00000079503	Ltb NCBI RGD Ensembl Show fit	lymphotoxin beta
chr1_-_101741441 Show fit	16.81	ENSRNOT00000028570	Sult2b1 NCBI RGD Ensembl Show fit	sulfotransferase family 2B member 1
chr1_-_88920291 Show fit	16.81	ENSRNOT00000028306	Kirrel2 NCBI RGD Ensembl Show fit	kin of IRRE like 2 (Drosophila)
chr6_-_138632159 Show fit	16.77	ENSRNOT00000082921 ENSRNOT00000040702	Ighm NCBI RGD Ensembl Show fit	immunoglobulin heavy constant mu
chr10_+_66942398 Show fit	16.75	ENSRNOT00000018986	Rab11fip4 NCBI RGD Ensembl Show fit	RAB11 family interacting protein 4
chr12_+_2134022 Show fit	16.74	ENSRNOT00000001305	Camsap3 NCBI RGD Ensembl Show fit	calmodulin regulated spectrin-associated protein family, member 3
chr19_+_3325893 Show fit	16.65	ENSRNOT00000048879	RGD1565617 NCBI RGD Ensembl Show fit	similar to Ig variable region, light chain
chr5_-_160405050 Show fit	16.58	ENSRNOT00000081899	Ctrc NCBI RGD Ensembl Show fit	chymotrypsin C
chr10_-_91291774 Show fit	16.48	ENSRNOT00000004356	LOC100361655 NCBI RGD Ensembl Show fit	rCG33642-like
chr3_-_148312420 Show fit	16.37	ENSRNOT00000047416 ENSRNOT00000081272	Bcl2l1 NCBI RGD Ensembl Show fit	Bcl2-like 1
chr4_-_132171153 Show fit	16.37	ENSRNOT00000015058 ENSRNOT00000015075	Prok2 NCBI RGD Ensembl Show fit	prokineticin 2
chr1_-_169344306 Show fit	16.32	ENSRNOT00000022852	Ubqlnl NCBI RGD Ensembl Show fit	ubiquilin-like
chr6_+_139405966 Show fit	16.19	ENSRNOT00000088974	AABR07065693.3 NCBI RGD Ensembl Show fit
chr2_-_88113029 Show fit	16.16	ENSRNOT00000013354	Car2 NCBI RGD Ensembl Show fit	carbonic anhydrase 2
chr1_+_15093599 Show fit	16.16	ENSRNOT00000016354	Il22ra2 NCBI RGD Ensembl Show fit	interleukin 22 receptor subunit alpha 2
chr2_+_252263386 Show fit	16.15	ENSRNOT00000092913 ENSRNOT00000084034 ENSRNOT00000041186 ENSRNOT00000092931	Ssx2ip NCBI RGD Ensembl Show fit	SSX family member 2 interacting protein
chrX_-_156155014 Show fit	16.09	ENSRNOT00000088637	LOC102552182 NCBI RGD Ensembl Show fit	L antigen family member 3-like
chr4_+_109497962 Show fit	15.97	ENSRNOT00000057869	Reg1a NCBI RGD Ensembl Show fit	regenerating family member 1 alpha
chr3_+_119015412 Show fit	15.96	ENSRNOT00000013605	Slc27a2 NCBI RGD Ensembl Show fit	solute carrier family 27 member 2
chr7_+_38945836 Show fit	15.91	ENSRNOT00000006455	Ccer1 NCBI RGD Ensembl Show fit	coiled-coil glutamate-rich protein 1
chr8_-_49308806 Show fit	15.81	ENSRNOT00000047291	Cd3e NCBI RGD Ensembl Show fit	CD3e molecule
chr7_+_130296897 Show fit	15.74	ENSRNOT00000044854	Adm2 NCBI RGD Ensembl Show fit	adrenomedullin 2
chr7_-_102298522 Show fit	15.69	ENSRNOT00000006273	A1bg NCBI RGD Ensembl Show fit	alpha-1-B glycoprotein
chr2_-_112831476 Show fit	15.67	ENSRNOT00000018055	Ect2 NCBI RGD Ensembl Show fit	epithelial cell transforming 2
chrX_+_78196300 Show fit	15.66	ENSRNOT00000048695	P2ry10 NCBI RGD Ensembl Show fit	purinergic receptor P2Y10
chr6_-_138736203 Show fit	15.61	ENSRNOT00000052021	LOC100360169 NCBI RGD Ensembl Show fit	rCG21044-like
chr3_-_2853272 Show fit	15.60	ENSRNOT00000023022	Fcna NCBI RGD Ensembl Show fit	ficolin A
chr2_+_116416507 Show fit	15.57	ENSRNOT00000030700	Actrt3 NCBI RGD Ensembl Show fit	actin-related protein T3

Network of associatons between targets according to the STRING database.

First level regulatory network of Tcf4_Mesp1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
18.4	147.4	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
15.5	15.5	GO:1990379	lipid transport across blood brain barrier(GO:1990379)
11.2	33.7	GO:0015680	intracellular copper ion transport(GO:0015680)
10.8	32.3	GO:1905245	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
9.2	36.6	GO:0034240	negative regulation of macrophage fusion(GO:0034240)
8.3	33.0	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
8.2	32.9	GO:2000852	regulation of corticosterone secretion(GO:2000852)
7.7	30.8	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
7.4	36.8	GO:0032849	positive regulation of cellular pH reduction(GO:0032849)
7.2	43.1	GO:0032439	endosome localization(GO:0032439)
7.1	21.2	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
7.0	28.1	GO:0046351	disaccharide biosynthetic process(GO:0046351)
6.7	20.0	GO:0032242	regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) negative regulation of long term synaptic depression(GO:1900453)
6.6	13.3	GO:0071661	granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
6.6	39.5	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
6.3	19.0	GO:0010752	regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
6.2	18.5	GO:0038163	thrombopoietin-mediated signaling pathway(GO:0038163)
6.0	24.0	GO:0060066	oviduct development(GO:0060066)
5.9	23.7	GO:0035625	receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
5.9	88.8	GO:0048733	sebaceous gland development(GO:0048733)
5.9	29.4	GO:0060327	cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
5.8	34.7	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
5.5	22.2	GO:0021842	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
5.5	16.4	GO:1905218	cellular response to astaxanthin(GO:1905218)
5.4	10.8	GO:0042977	regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
5.3	16.0	GO:1990868	response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
5.2	73.0	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
5.0	15.1	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
4.9	14.7	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
4.7	42.3	GO:0070673	response to interleukin-18(GO:0070673)
4.7	18.7	GO:0070495	regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
4.6	23.1	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664)
4.6	13.8	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
4.5	22.7	GO:0030070	insulin processing(GO:0030070)
4.5	17.9	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
4.4	13.3	GO:0030719	oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
4.4	61.2	GO:0044752	response to human chorionic gonadotropin(GO:0044752)
4.4	34.8	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
4.3	13.0	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
4.2	16.9	GO:0051311	meiotic metaphase plate congression(GO:0051311)
4.2	12.6	GO:0007066	female meiosis sister chromatid cohesion(GO:0007066)
4.2	20.9	GO:0045218	zonula adherens maintenance(GO:0045218)
4.1	12.2	GO:0002380	immunoglobulin secretion involved in immune response(GO:0002380)
4.1	8.1	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
3.9	3.9	GO:0010716	negative regulation of extracellular matrix disassembly(GO:0010716)
3.9	19.3	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
3.8	7.6	GO:0032423	regulation of mismatch repair(GO:0032423)
3.8	18.9	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
3.7	18.6	GO:0010037	response to carbon dioxide(GO:0010037)
3.7	11.0	GO:0010034	response to acetate(GO:0010034)
3.6	10.9	GO:1990743	protein sialylation(GO:1990743)
3.6	14.5	GO:0070543	response to linoleic acid(GO:0070543)
3.6	10.9	GO:1902226	regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
3.5	14.2	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
3.5	35.2	GO:0032782	bile acid secretion(GO:0032782)
3.5	17.5	GO:0040038	polar body extrusion after meiotic divisions(GO:0040038)
3.4	10.3	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
3.3	33.3	GO:0061365	positive regulation of triglyceride lipase activity(GO:0061365)
3.3	13.3	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
3.3	16.5	GO:0090274	positive regulation of somatostatin secretion(GO:0090274)
3.3	19.6	GO:0010587	miRNA catabolic process(GO:0010587)
3.2	12.7	GO:0035986	senescence-associated heterochromatin focus assembly(GO:0035986)
3.2	12.7	GO:0071226	cellular response to molecule of fungal origin(GO:0071226)
3.1	9.4	GO:0042509	regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
3.1	21.8	GO:0010529	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
3.1	3.1	GO:0021730	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
3.0	33.5	GO:0070862	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
3.0	9.1	GO:0002232	leukocyte chemotaxis involved in inflammatory response(GO:0002232) myeloid dendritic cell activation involved in immune response(GO:0002277)
3.0	12.1	GO:0070839	divalent metal ion export(GO:0070839)
3.0	21.0	GO:0035879	plasma membrane lactate transport(GO:0035879)
2.9	8.8	GO:1900368	regulation of RNA interference(GO:1900368)
2.9	2.9	GO:0044725	chromatin reprogramming in the zygote(GO:0044725)
2.9	14.6	GO:0061727	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
2.9	11.6	GO:1904616	regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
2.9	17.5	GO:0021633	optic nerve structural organization(GO:0021633)
2.9	8.7	GO:0006667	sphinganine metabolic process(GO:0006667)
2.9	23.2	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
2.9	8.6	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
2.9	42.8	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
2.9	11.4	GO:0018992	germ-line sex determination(GO:0018992)
2.8	11.2	GO:0034436	glycoprotein transport(GO:0034436)
2.8	2.8	GO:0006649	phospholipid transfer to membrane(GO:0006649)
2.7	2.7	GO:0010899	regulation of phosphatidylcholine catabolic process(GO:0010899)
2.7	41.0	GO:0007288	sperm axoneme assembly(GO:0007288)
2.7	13.7	GO:0051594	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
2.7	5.5	GO:0045819	positive regulation of glycogen catabolic process(GO:0045819)
2.7	21.6	GO:0045348	positive regulation of MHC class II biosynthetic process(GO:0045348)
2.7	16.2	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
2.7	13.4	GO:0016191	synaptic vesicle uncoating(GO:0016191)
2.7	10.6	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
2.6	10.6	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
2.6	15.9	GO:0007198	adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
2.6	15.8	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
2.6	7.9	GO:0034769	basement membrane disassembly(GO:0034769)
2.6	7.9	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
2.6	18.2	GO:1904117	cellular response to vasopressin(GO:1904117)
2.6	7.8	GO:0043606	histidine catabolic process to glutamate and formamide(GO:0019556) formamide metabolic process(GO:0043606)
2.6	18.1	GO:0010216	maintenance of DNA methylation(GO:0010216)
2.6	7.8	GO:0034486	vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741)
2.6	10.3	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
2.6	12.9	GO:0090168	Golgi reassembly(GO:0090168)
2.6	30.9	GO:0006968	cellular defense response(GO:0006968)
2.5	20.4	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
2.5	5.1	GO:1903977	positive regulation of glial cell migration(GO:1903977)
2.5	12.7	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
2.5	7.5	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
2.5	10.0	GO:0071802	negative regulation of podosome assembly(GO:0071802)
2.5	7.5	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
2.5	2.5	GO:0046544	development of secondary male sexual characteristics(GO:0046544)
2.4	17.0	GO:0019482	beta-alanine metabolic process(GO:0019482)
2.4	14.5	GO:0002568	somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
2.4	7.1	GO:0030824	negative regulation of cGMP metabolic process(GO:0030824)
2.4	16.6	GO:0033572	transferrin transport(GO:0033572)
2.4	7.1	GO:0045082	positive regulation of interleukin-10 biosynthetic process(GO:0045082)
2.3	20.9	GO:0010572	positive regulation of platelet activation(GO:0010572)
2.3	2.3	GO:0097212	lysosomal membrane organization(GO:0097212)
2.3	9.2	GO:0014028	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) notochord formation(GO:0014028)
2.3	4.5	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
2.3	11.4	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
2.3	6.8	GO:2000620	positive regulation of histone H4-K16 acetylation(GO:2000620)
2.2	6.7	GO:0071395	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
2.2	13.4	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
2.2	15.5	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
2.2	4.4	GO:0033206	meiotic cytokinesis(GO:0033206)
2.2	8.8	GO:0060431	primary lung bud formation(GO:0060431)
2.1	8.6	GO:0097026	dendritic cell dendrite assembly(GO:0097026)
2.1	2.1	GO:1902995	regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
2.1	16.6	GO:0006751	glutathione catabolic process(GO:0006751)
2.1	10.3	GO:0002036	regulation of L-glutamate transport(GO:0002036)
2.0	8.2	GO:0006564	L-serine biosynthetic process(GO:0006564)
2.0	12.2	GO:0046874	quinolinate metabolic process(GO:0046874)
2.0	46.5	GO:0030574	collagen catabolic process(GO:0030574)
2.0	8.1	GO:1904781	positive regulation of protein localization to centrosome(GO:1904781)
2.0	8.1	GO:0040009	regulation of growth rate(GO:0040009)
2.0	14.1	GO:0000103	sulfate assimilation(GO:0000103)
2.0	10.0	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
2.0	8.0	GO:0032701	negative regulation of interleukin-18 production(GO:0032701)
2.0	13.9	GO:0051126	negative regulation of actin nucleation(GO:0051126)
2.0	11.8	GO:0071386	cellular response to corticosterone stimulus(GO:0071386)
2.0	7.9	GO:0050893	sensory processing(GO:0050893)
2.0	5.9	GO:0016539	intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
1.9	15.5	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
1.9	5.8	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
1.9	3.9	GO:0060545	positive regulation of necroptotic process(GO:0060545)
1.9	36.2	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
1.9	7.6	GO:0061083	regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
1.9	17.0	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
1.9	3.8	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
1.9	1.9	GO:0038183	bile acid signaling pathway(GO:0038183)
1.9	16.8	GO:0042159	lipoprotein catabolic process(GO:0042159)
1.9	5.6	GO:0060086	circadian temperature homeostasis(GO:0060086)
1.9	16.8	GO:0070314	G1 to G0 transition(GO:0070314)
1.9	16.7	GO:0070091	glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
1.8	9.2	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
1.8	7.3	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
1.8	10.9	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
1.8	5.5	GO:0046061	dATP catabolic process(GO:0046061)
1.8	7.3	GO:0015888	thiamine transport(GO:0015888)
1.8	10.9	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
1.8	7.1	GO:1901837	negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
1.8	7.1	GO:0097401	synaptic vesicle lumen acidification(GO:0097401)
1.8	8.8	GO:0019323	pentose catabolic process(GO:0019323)
1.8	12.3	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
1.8	22.9	GO:0034587	piRNA metabolic process(GO:0034587)
1.8	5.3	GO:0018094	protein polyglycylation(GO:0018094)
1.7	3.5	GO:0014045	establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009) renal outer medulla development(GO:0072054)
1.7	22.5	GO:1904667	negative regulation of ubiquitin protein ligase activity(GO:1904667)
1.7	5.2	GO:1990108	protein linear deubiquitination(GO:1990108)
1.7	5.2	GO:0060369	positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
1.7	3.4	GO:0097477	lateral motor column neuron migration(GO:0097477)
1.7	8.5	GO:0071500	cellular response to nitrosative stress(GO:0071500)
1.7	33.5	GO:0006910	phagocytosis, recognition(GO:0006910)
1.6	24.7	GO:0006020	inositol metabolic process(GO:0006020)
1.6	19.7	GO:2000650	negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
1.6	13.1	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
1.6	8.2	GO:0006563	L-serine metabolic process(GO:0006563)
1.6	22.9	GO:0061029	eyelid development in camera-type eye(GO:0061029)
1.6	45.4	GO:1905144	acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
1.6	11.3	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
1.6	6.4	GO:0070368	positive regulation of hepatocyte differentiation(GO:0070368)
1.6	4.8	GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
1.6	3.2	GO:0045959	negative regulation of complement activation, classical pathway(GO:0045959)
1.6	4.7	GO:0090467	L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
1.5	23.2	GO:0043312	neutrophil degranulation(GO:0043312)
1.5	16.9	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
1.5	12.3	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
1.5	19.8	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
1.5	18.2	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
1.5	13.4	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
1.5	4.4	GO:0098971	anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
1.5	11.8	GO:0014054	positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
1.5	5.9	GO:0080154	regulation of fertilization(GO:0080154)
1.5	2.9	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
1.5	7.3	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
1.5	2.9	GO:0071454	cellular response to anoxia(GO:0071454)
1.4	8.7	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
1.4	4.3	GO:1902269	positive regulation of polyamine transmembrane transport(GO:1902269)
1.4	4.3	GO:1904444	regulation of establishment of Sertoli cell barrier(GO:1904444)
1.4	4.3	GO:0015891	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.4	4.3	GO:1904373	response to kainic acid(GO:1904373)
1.4	12.8	GO:0021796	cerebral cortex regionalization(GO:0021796)
1.4	21.3	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
1.4	5.7	GO:0001923	B-1 B cell differentiation(GO:0001923)
1.4	41.0	GO:0002675	positive regulation of acute inflammatory response(GO:0002675)
1.4	4.2	GO:0016267	O-glycan processing, core 1(GO:0016267)
1.4	4.2	GO:0003051	angiotensin-mediated drinking behavior(GO:0003051)
1.4	7.0	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
1.4	27.5	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
1.4	85.0	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
1.4	4.1	GO:0032383	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
1.3	10.8	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
1.3	5.4	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
1.3	9.2	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
1.3	15.7	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
1.3	6.5	GO:0045590	negative regulation of regulatory T cell differentiation(GO:0045590)
1.3	3.9	GO:1904685	regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) positive regulation of metalloendopeptidase activity(GO:1904685)
1.3	3.9	GO:0042489	negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
1.3	2.6	GO:0090427	activation of meiosis(GO:0090427)
1.3	5.1	GO:0034653	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
1.3	1.3	GO:2000195	negative regulation of female gonad development(GO:2000195)
1.3	13.9	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
1.2	3.7	GO:0021997	neural plate axis specification(GO:0021997)
1.2	41.7	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
1.2	13.4	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
1.2	24.4	GO:0048240	sperm capacitation(GO:0048240)
1.2	3.6	GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
1.2	14.4	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
1.2	21.5	GO:0043496	regulation of protein homodimerization activity(GO:0043496)
1.2	13.1	GO:2000018	regulation of male gonad development(GO:2000018)
1.2	5.9	GO:0015755	carbohydrate utilization(GO:0009758) fructose transport(GO:0015755)
1.2	4.7	GO:1903576	response to L-arginine(GO:1903576)
1.2	10.7	GO:0050957	equilibrioception(GO:0050957)
1.2	9.4	GO:0016056	rhodopsin mediated signaling pathway(GO:0016056)
1.2	9.4	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
1.2	16.4	GO:0015693	magnesium ion transport(GO:0015693) magnesium ion transmembrane transport(GO:1903830)
1.2	5.9	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
1.2	3.5	GO:1904152	regulation of retrograde protein transport, ER to cytosol(GO:1904152)
1.2	11.7	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655)
1.2	5.8	GO:0051754	male meiosis chromosome segregation(GO:0007060) meiotic sister chromatid cohesion, centromeric(GO:0051754)
1.2	7.0	GO:0038169	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
1.2	10.4	GO:0006735	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
1.2	4.6	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
1.1	3.4	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
1.1	16.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
1.1	14.6	GO:0042832	defense response to protozoan(GO:0042832)
1.1	17.9	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
1.1	11.1	GO:0030225	macrophage differentiation(GO:0030225)
1.1	3.3	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
1.1	10.0	GO:0030223	neutrophil differentiation(GO:0030223)
1.1	2.2	GO:0031394	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
1.1	3.3	GO:0021586	pons maturation(GO:0021586) olefin metabolic process(GO:1900673)
1.1	6.5	GO:0045113	regulation of integrin biosynthetic process(GO:0045113)
1.1	3.2	GO:0048936	neurofilament bundle assembly(GO:0033693) peripheral nervous system neuron axonogenesis(GO:0048936)
1.1	8.5	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
1.1	18.9	GO:0001516	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
1.0	4.2	GO:0043046	DNA methylation involved in gamete generation(GO:0043046)
1.0	2.1	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
1.0	10.4	GO:0070327	thyroid hormone transport(GO:0070327)
1.0	3.1	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
1.0	9.3	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
1.0	14.4	GO:0045581	negative regulation of T cell differentiation(GO:0045581)
1.0	3.0	GO:1904211	membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
1.0	52.6	GO:0002260	lymphocyte homeostasis(GO:0002260)
1.0	3.0	GO:2000851	positive regulation of cortisol secretion(GO:0051464) positive regulation of glucocorticoid secretion(GO:2000851)
1.0	7.0	GO:0046600	negative regulation of centriole replication(GO:0046600)
1.0	7.0	GO:0046655	folic acid metabolic process(GO:0046655)
1.0	9.9	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
1.0	2.9	GO:2000211	negative regulation of cellular amino acid metabolic process(GO:0045763) regulation of glutamate metabolic process(GO:2000211)
1.0	3.8	GO:0051958	methotrexate transport(GO:0051958)
1.0	1.9	GO:0045919	positive regulation of cytolysis(GO:0045919)
0.9	3.8	GO:0030321	transepithelial chloride transport(GO:0030321)
0.9	3.8	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.9	8.4	GO:0015732	prostaglandin transport(GO:0015732)
0.9	3.6	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.9	2.7	GO:0071469	cellular response to alkaline pH(GO:0071469)
0.9	5.3	GO:2000402	negative regulation of lymphocyte migration(GO:2000402)
0.9	5.3	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.9	2.6	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.9	3.5	GO:0021871	forebrain regionalization(GO:0021871)
0.9	6.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.9	7.0	GO:0043102	amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.9	8.7	GO:0070995	NADPH oxidation(GO:0070995)
0.9	4.3	GO:0050925	negative regulation of negative chemotaxis(GO:0050925)
0.9	5.2	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.9	3.4	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.9	6.9	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.8	6.8	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.8	1.7	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406)
0.8	22.7	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.8	7.6	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.8	1.7	GO:0031448	regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.8	6.7	GO:0019372	lipoxygenase pathway(GO:0019372)
0.8	3.3	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.8	9.7	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.8	4.8	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.8	4.8	GO:0097116	gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.8	8.7	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.8	21.4	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.8	3.2	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
0.8	43.1	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.8	7.0	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.8	5.5	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.8	22.5	GO:0070228	regulation of lymphocyte apoptotic process(GO:0070228)
0.8	4.6	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.8	3.1	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.8	3.8	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.8	8.4	GO:0006228	UTP biosynthetic process(GO:0006228)
0.8	2.3	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.8	9.0	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.8	15.0	GO:0010447	response to acidic pH(GO:0010447)
0.7	5.2	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.7	4.4	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.7	4.4	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.7	3.6	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.7	0.7	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904)
0.7	10.8	GO:0046337	phosphatidylethanolamine metabolic process(GO:0046337)
0.7	3.6	GO:0003157	endocardium development(GO:0003157)
0.7	2.9	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.7	2.9	GO:0018211	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.7	9.1	GO:0051014	actin filament severing(GO:0051014)
0.7	3.5	GO:2000773	negative regulation of cellular senescence(GO:2000773)
0.7	3.4	GO:1901678	iron coordination entity transport(GO:1901678)
0.7	12.3	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.7	2.0	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798) telencephalon regionalization(GO:0021978)
0.7	2.7	GO:0035494	SNARE complex disassembly(GO:0035494)
0.7	20.7	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779)
0.7	2.7	GO:0044107	cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
0.7	2.6	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.7	6.6	GO:0000733	DNA strand renaturation(GO:0000733)
0.7	13.1	GO:0060037	pharyngeal system development(GO:0060037)
0.7	6.5	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.6	2.6	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.6	0.6	GO:2000777	positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.6	1.9	GO:0042350	GDP-L-fucose biosynthetic process(GO:0042350)
0.6	1.3	GO:0044268	multicellular organismal protein metabolic process(GO:0044268)
0.6	2.6	GO:1904816	positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.6	1.3	GO:0071718	sodium-independent icosanoid transport(GO:0071718)
0.6	7.6	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.6	3.8	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.6	1.9	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.6	8.7	GO:0016578	histone deubiquitination(GO:0016578)
0.6	1.2	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.6	1.8	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.6	1.8	GO:0018916	nitrobenzene metabolic process(GO:0018916)
0.6	10.4	GO:0006895	Golgi to endosome transport(GO:0006895)
0.6	9.2	GO:0044364	killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.6	0.6	GO:1904000	positive regulation of eating behavior(GO:1904000)
0.6	4.2	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.6	3.0	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.6	9.6	GO:0045671	negative regulation of osteoclast differentiation(GO:0045671)
0.6	12.0	GO:0044818	mitotic G2/M transition checkpoint(GO:0044818)
0.6	5.9	GO:0035524	proline transmembrane transport(GO:0035524)
0.6	2.3	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
0.6	1.7	GO:1901994	negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.6	15.7	GO:0030261	chromosome condensation(GO:0030261)
0.6	6.8	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.6	5.7	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.6	5.6	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.6	1.7	GO:0051005	regulation of lipoprotein lipase activity(GO:0051004) negative regulation of lipoprotein lipase activity(GO:0051005)
0.6	15.1	GO:0048536	spleen development(GO:0048536)
0.6	11.2	GO:0050482	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.6	4.5	GO:0046710	GDP metabolic process(GO:0046710)
0.6	4.4	GO:0097264	self proteolysis(GO:0097264)
0.6	3.9	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.6	5.0	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.5	1.1	GO:0060157	urinary bladder development(GO:0060157)
0.5	1.6	GO:0033026	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) negative regulation of mast cell apoptotic process(GO:0033026) mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.5	3.8	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
0.5	4.8	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.5	16.9	GO:0031648	protein destabilization(GO:0031648)
0.5	3.7	GO:2001275	positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.5	2.6	GO:0048664	neuron fate determination(GO:0048664)
0.5	3.1	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.5	2.1	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.5	4.1	GO:0014022	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.5	5.7	GO:0046548	retinal rod cell development(GO:0046548)
0.5	7.7	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.5	4.6	GO:0030432	peristalsis(GO:0030432)
0.5	6.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.5	3.0	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.5	8.5	GO:0007602	phototransduction(GO:0007602)
0.5	11.9	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.5	1.5	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.5	3.4	GO:0016559	peroxisome fission(GO:0016559)
0.5	5.4	GO:0044821	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.5	2.9	GO:0046836	glycolipid transport(GO:0046836)
0.5	3.4	GO:0018095	protein polyglutamylation(GO:0018095)
0.5	44.4	GO:0007586	digestion(GO:0007586)
0.5	1.4	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.5	1.4	GO:0071038	nuclear mRNA surveillance of mRNA 3'-end processing(GO:0071031) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription(GO:0071049)
0.5	1.9	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.5	2.4	GO:0010273	detoxification of copper ion(GO:0010273) response to chromate(GO:0046687) stress response to copper ion(GO:1990169)
0.5	2.4	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.5	1.8	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.5	2.3	GO:0043615	astrocyte cell migration(GO:0043615)
0.5	0.5	GO:0008078	mesodermal cell migration(GO:0008078)
0.5	6.4	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.5	12.7	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.4	2.7	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.4	4.5	GO:0060081	membrane hyperpolarization(GO:0060081)
0.4	0.4	GO:0002525	acute inflammatory response to non-antigenic stimulus(GO:0002525)
0.4	1.7	GO:0031133	regulation of axon diameter(GO:0031133)
0.4	1.3	GO:0090344	negative regulation of cell aging(GO:0090344)
0.4	1.3	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.4	2.1	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.4	4.7	GO:0002347	response to tumor cell(GO:0002347)
0.4	15.3	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.4	11.2	GO:0009649	entrainment of circadian clock(GO:0009649)
0.4	1.6	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.4	15.1	GO:0007628	adult walking behavior(GO:0007628)
0.4	7.9	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.4	2.0	GO:0003374	dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.4	7.3	GO:0042403	thyroid hormone metabolic process(GO:0042403)
0.4	1.9	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.4	1.9	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.4	1.9	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.4	1.8	GO:0060405	regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406)
0.4	2.6	GO:0051661	maintenance of centrosome location(GO:0051661)
0.4	2.9	GO:0097119	postsynaptic density protein 95 clustering(GO:0097119)
0.4	1.1	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.4	1.4	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.4	0.7	GO:0016078	tRNA catabolic process(GO:0016078)
0.4	1.8	GO:0046015	regulation of transcription by glucose(GO:0046015)
0.4	7.1	GO:0055069	zinc ion homeostasis(GO:0055069)
0.4	4.2	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.3	1.0	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.3	1.4	GO:0001771	immunological synapse formation(GO:0001771)
0.3	7.6	GO:0019432	triglyceride biosynthetic process(GO:0019432)
0.3	3.1	GO:0051013	microtubule severing(GO:0051013)
0.3	0.7	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350) spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.3	0.3	GO:0072076	nephrogenic mesenchyme development(GO:0072076)
0.3	8.1	GO:0072678	T cell migration(GO:0072678)
0.3	1.6	GO:0060613	fat pad development(GO:0060613)
0.3	4.2	GO:0051292	nuclear pore complex assembly(GO:0051292)
0.3	6.2	GO:0034508	centromere complex assembly(GO:0034508)
0.3	2.6	GO:0098703	calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.3	1.6	GO:0097012	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.3	3.8	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.3	2.2	GO:0043686	co-translational protein modification(GO:0043686)
0.3	18.9	GO:0051028	mRNA transport(GO:0051028)
0.3	3.7	GO:0036065	fucosylation(GO:0036065)
0.3	7.0	GO:0010458	exit from mitosis(GO:0010458)
0.3	5.1	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.3	3.3	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.3	2.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.3	3.3	GO:0048671	negative regulation of collateral sprouting(GO:0048671)
0.3	2.9	GO:0061436	establishment of skin barrier(GO:0061436)
0.3	1.1	GO:0036015	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.3	1.4	GO:0035063	nuclear speck organization(GO:0035063)
0.3	1.4	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.3	2.5	GO:1900016	negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.3	10.9	GO:0006611	protein export from nucleus(GO:0006611)
0.3	1.9	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.3	11.8	GO:0003382	epithelial cell morphogenesis(GO:0003382)
0.3	0.5	GO:0060594	mammary gland specification(GO:0060594)
0.3	0.8	GO:0098953	receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.3	2.7	GO:0090070	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.3	3.2	GO:0034063	stress granule assembly(GO:0034063)
0.3	3.3	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.3	2.5	GO:0050718	regulation of interleukin-1 beta secretion(GO:0050706) positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.3	1.3	GO:0071630	nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.2	2.7	GO:2000291	regulation of myoblast proliferation(GO:2000291)
0.2	4.4	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.2	2.2	GO:0007638	mechanosensory behavior(GO:0007638)
0.2	2.2	GO:0048745	smooth muscle tissue development(GO:0048745)
0.2	4.4	GO:0019835	cytolysis(GO:0019835)
0.2	3.9	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.2	2.7	GO:0000338	protein deneddylation(GO:0000338)
0.2	0.5	GO:0061535	glutamate secretion, neurotransmission(GO:0061535)
0.2	0.5	GO:0003430	growth plate cartilage chondrocyte growth(GO:0003430)
0.2	3.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.2	7.5	GO:0043616	keratinocyte proliferation(GO:0043616)
0.2	0.7	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.2	4.8	GO:0045839	negative regulation of mitotic nuclear division(GO:0045839)
0.2	1.6	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.2	1.8	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.2	1.8	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.2	0.4	GO:0070268	cornification(GO:0070268)
0.2	4.6	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.2	6.2	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.2	2.8	GO:0007140	male meiosis(GO:0007140)
0.2	0.6	GO:0060023	soft palate development(GO:0060023)
0.2	1.0	GO:0035188	blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.2	2.2	GO:0035067	negative regulation of histone acetylation(GO:0035067)
0.2	6.9	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2	3.5	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.2	10.8	GO:0018107	peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.2	3.0	GO:0007035	vacuolar acidification(GO:0007035)
0.2	0.8	GO:0045901	positive regulation of translational elongation(GO:0045901)
0.2	4.5	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.2	0.8	GO:0097384	cellular lipid biosynthetic process(GO:0097384)
0.2	1.1	GO:0070914	UV-damage excision repair(GO:0070914)
0.2	4.6	GO:0035428	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.2	2.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.2	63.4	GO:0007283	spermatogenesis(GO:0007283)
0.2	1.7	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2	0.3	GO:1900108	negative regulation of nodal signaling pathway(GO:1900108)
0.2	1.9	GO:0045475	locomotor rhythm(GO:0045475)
0.2	1.0	GO:1901725	regulation of histone deacetylase activity(GO:1901725) positive regulation of histone deacetylase activity(GO:1901727)
0.2	3.8	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.2	0.5	GO:0033578	protein glycosylation in Golgi(GO:0033578) regulation of protein glycosylation in Golgi(GO:0090283)
0.2	4.2	GO:0002548	monocyte chemotaxis(GO:0002548)
0.2	0.5	GO:1901533	negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.2	3.4	GO:0030318	melanocyte differentiation(GO:0030318)
0.2	0.3	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
0.2	3.6	GO:0016925	protein sumoylation(GO:0016925)
0.2	2.7	GO:0043968	histone H2A acetylation(GO:0043968)
0.2	2.1	GO:0030262	apoptotic nuclear changes(GO:0030262)
0.2	1.8	GO:0006336	DNA replication-independent nucleosome assembly(GO:0006336)
0.1	2.9	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.1	0.3	GO:0032074	negative regulation of nuclease activity(GO:0032074)
0.1	0.5	GO:1902993	positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.1	1.8	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.1	1.6	GO:0036159	inner dynein arm assembly(GO:0036159)
0.1	1.0	GO:0051294	establishment of spindle orientation(GO:0051294)
0.1	1.5	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.1	3.3	GO:0097502	mannosylation(GO:0097502)
0.1	0.2	GO:0014908	myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.1	0.8	GO:0044030	regulation of DNA methylation(GO:0044030)
0.1	1.4	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592)
0.1	0.6	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1	0.8	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.1	1.1	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.1	1.3	GO:0002717	positive regulation of natural killer cell mediated immunity(GO:0002717)
0.1	2.5	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.1	14.4	GO:0007059	chromosome segregation(GO:0007059)
0.1	1.6	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.1	0.7	GO:0032596	protein transport into membrane raft(GO:0032596)
0.1	1.3	GO:0019433	triglyceride catabolic process(GO:0019433)
0.1	0.4	GO:0042256	mature ribosome assembly(GO:0042256)
0.1	0.6	GO:0035881	amacrine cell differentiation(GO:0035881)
0.1	2.1	GO:0042491	auditory receptor cell differentiation(GO:0042491)
0.1	0.4	GO:0009405	pathogenesis(GO:0009405)
0.1	0.9	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	9.0	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.1	2.3	GO:0030166	proteoglycan biosynthetic process(GO:0030166)
0.1	1.4	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1	1.3	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.3	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.1	3.2	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.1	6.9	GO:0006413	translational initiation(GO:0006413)
0.1	0.4	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1	2.6	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1	0.3	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	3.5	GO:0006414	translational elongation(GO:0006414)
0.1	0.2	GO:0038172	negative regulation of T-helper 1 type immune response(GO:0002826) interleukin-33-mediated signaling pathway(GO:0038172)
0.1	0.2	GO:0080120	CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1	0.8	GO:0007616	long-term memory(GO:0007616)
0.1	0.1	GO:0035315	hair cell differentiation(GO:0035315)
0.1	0.6	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1	0.5	GO:0070129	regulation of mitochondrial translation(GO:0070129)
0.1	0.3	GO:0002446	neutrophil mediated immunity(GO:0002446)
0.1	1.9	GO:0032092	positive regulation of protein binding(GO:0032092)
0.1	2.0	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	1.0	GO:0060669	embryonic placenta morphogenesis(GO:0060669) labyrinthine layer morphogenesis(GO:0060713)
0.0	1.7	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0	0.1	GO:1990253	positive regulation of TORC1 signaling(GO:1904263) cellular response to leucine starvation(GO:1990253)
0.0	0.3	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.9	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.7	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	1.1	GO:0042073	intraciliary transport(GO:0042073)
0.0	1.0	GO:0071361	cellular response to ethanol(GO:0071361)
0.0	0.2	GO:0050917	sensory perception of umami taste(GO:0050917)
0.0	0.5	GO:0048821	erythrocyte development(GO:0048821)
0.0	0.2	GO:0006586	tryptophan metabolic process(GO:0006568) indolalkylamine metabolic process(GO:0006586)
0.0	3.3	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
0.0	0.5	GO:0045116	protein neddylation(GO:0045116)
0.0	0.1	GO:0036451	cap mRNA methylation(GO:0036451)
0.0	0.4	GO:1903432	regulation of TORC1 signaling(GO:1903432)
0.0	0.5	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.9	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.1	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.8	GO:0016575	histone deacetylation(GO:0016575)
0.0	0.2	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0	0.6	GO:0006338	chromatin remodeling(GO:0006338)
0.0	0.2	GO:0045682	regulation of epidermis development(GO:0045682)
0.0	0.2	GO:0045047	protein targeting to ER(GO:0045047)
0.0	0.1	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.0	0.7	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.9	39.5	GO:0002947	tumor necrosis factor receptor superfamily complex(GO:0002947)
7.5	30.1	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
7.3	21.9	GO:1990723	cytoplasmic periphery of the nuclear pore complex(GO:1990723)
6.9	55.3	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
6.2	30.9	GO:1990716	axonemal central apparatus(GO:1990716)
5.8	17.4	GO:0046691	intracellular canaliculus(GO:0046691)
5.6	16.7	GO:0032173	septin collar(GO:0032173)
5.3	21.3	GO:0097149	centralspindlin complex(GO:0097149)
4.9	34.3	GO:0097524	sperm plasma membrane(GO:0097524)
4.9	48.8	GO:0045179	apical cortex(GO:0045179)
4.1	41.3	GO:0042101	T cell receptor complex(GO:0042101)
3.8	18.8	GO:0070695	FHF complex(GO:0070695)
3.7	33.3	GO:0071546	pi-body(GO:0071546)
3.3	9.9	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
3.3	69.3	GO:0005922	connexon complex(GO:0005922)
3.0	29.7	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
3.0	8.9	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
2.7	19.1	GO:0036128	CatSper complex(GO:0036128)
2.7	29.8	GO:0097418	neurofibrillary tangle(GO:0097418)
2.7	13.4	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
2.6	15.9	GO:0036449	microtubule minus-end(GO:0036449)
2.6	7.8	GO:0005760	gamma DNA polymerase complex(GO:0005760)
2.6	15.5	GO:0005726	perichromatin fibrils(GO:0005726)
2.5	12.7	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
2.5	24.5	GO:0043219	lateral loop(GO:0043219)
2.4	33.2	GO:0072687	meiotic spindle(GO:0072687)
2.4	30.8	GO:0033391	chromatoid body(GO:0033391)
2.4	9.4	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
2.3	16.4	GO:0097136	Bcl-2 family protein complex(GO:0097136)
2.3	9.0	GO:0033269	internode region of axon(GO:0033269)
2.2	6.6	GO:0033165	interphotoreceptor matrix(GO:0033165)
2.1	65.4	GO:0042588	zymogen granule(GO:0042588)
2.1	10.3	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
2.0	29.4	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
2.0	5.9	GO:0044307	dendritic branch(GO:0044307)
1.9	26.4	GO:0044224	juxtaparanode region of axon(GO:0044224)
1.7	10.4	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
1.7	8.5	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
1.7	6.8	GO:0031436	BRCA1-BARD1 complex(GO:0031436)
1.7	9.9	GO:0043203	axon hillock(GO:0043203)
1.5	4.4	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
1.5	5.8	GO:0031092	platelet alpha granule membrane(GO:0031092)
1.4	7.2	GO:0035749	myelin sheath adaxonal region(GO:0035749)
1.4	2.8	GO:1990923	PET complex(GO:1990923)
1.4	46.8	GO:0001772	immunological synapse(GO:0001772)
1.4	4.2	GO:0044611	nuclear pore inner ring(GO:0044611)
1.3	6.5	GO:0043625	delta DNA polymerase complex(GO:0043625)
1.3	7.8	GO:0002081	outer acrosomal membrane(GO:0002081)
1.3	7.5	GO:0005785	signal recognition particle receptor complex(GO:0005785)
1.2	3.7	GO:0070821	tertiary granule membrane(GO:0070821)
1.2	20.8	GO:0031011	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
1.2	88.3	GO:0045095	keratin filament(GO:0045095)
1.2	7.1	GO:0097598	outer dynein arm(GO:0036157) sperm cytoplasmic droplet(GO:0097598)
1.2	10.6	GO:0098576	lumenal side of membrane(GO:0098576)
1.1	6.6	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
1.0	30.4	GO:0034451	centriolar satellite(GO:0034451)
1.0	3.0	GO:0032389	MutLalpha complex(GO:0032389)
1.0	21.7	GO:0001673	male germ cell nucleus(GO:0001673)
1.0	9.8	GO:0002177	manchette(GO:0002177)
1.0	9.8	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
1.0	3.9	GO:0044194	cytolytic granule(GO:0044194)
1.0	22.1	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.0	11.5	GO:0000801	central element(GO:0000801)
0.9	8.5	GO:0005921	gap junction(GO:0005921)
0.9	34.1	GO:0044295	axonal growth cone(GO:0044295)
0.9	17.1	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.9	2.7	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.9	10.6	GO:0035253	ciliary rootlet(GO:0035253)
0.8	3.3	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.8	15.3	GO:0032279	asymmetric synapse(GO:0032279)
0.8	11.2	GO:0032433	filopodium tip(GO:0032433)
0.8	3.2	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.8	94.1	GO:0072562	blood microparticle(GO:0072562)
0.8	21.6	GO:0000788	nuclear nucleosome(GO:0000788)
0.8	9.2	GO:0042575	DNA polymerase complex(GO:0042575)
0.7	8.9	GO:0032426	stereocilium tip(GO:0032426)
0.7	3.7	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.7	5.0	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.7	2.1	GO:0009328	phenylalanine-tRNA ligase complex(GO:0009328)
0.7	3.4	GO:0031085	BLOC-3 complex(GO:0031085)
0.7	5.4	GO:0005826	actomyosin contractile ring(GO:0005826)
0.7	2.7	GO:0030478	actin cap(GO:0030478)
0.7	3.3	GO:0001652	granular component(GO:0001652)
0.6	7.1	GO:0031010	ISWI-type complex(GO:0031010)
0.6	7.4	GO:0042581	specific granule(GO:0042581)
0.6	5.0	GO:0000242	pericentriolar material(GO:0000242)
0.6	5.6	GO:0001940	male pronucleus(GO:0001940)
0.6	6.7	GO:0042555	MCM complex(GO:0042555)
0.6	9.6	GO:0001520	outer dense fiber(GO:0001520)
0.6	3.6	GO:0097539	ciliary transition fiber(GO:0097539)
0.6	7.0	GO:0097431	mitotic spindle pole(GO:0097431)
0.6	8.7	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.6	10.9	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.6	2.3	GO:0000322	storage vacuole(GO:0000322)
0.6	2.8	GO:0061689	tricellular tight junction(GO:0061689)
0.6	11.8	GO:0000152	nuclear ubiquitin ligase complex(GO:0000152)
0.6	3.3	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.6	3.3	GO:0005787	signal peptidase complex(GO:0005787)
0.5	9.9	GO:0045277	respiratory chain complex IV(GO:0045277)
0.5	7.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.5	5.5	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.5	18.5	GO:0055038	recycling endosome membrane(GO:0055038)
0.5	2.1	GO:0031592	centrosomal corona(GO:0031592)
0.5	7.5	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.5	2.7	GO:0070195	growth hormone receptor complex(GO:0070195)
0.5	14.2	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.5	5.2	GO:0070652	HAUS complex(GO:0070652)
0.5	33.0	GO:0031901	early endosome membrane(GO:0031901)
0.5	13.8	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.5	2.5	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.5	10.7	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.5	56.6	GO:0030139	endocytic vesicle(GO:0030139)
0.5	1.5	GO:0032398	MHC class Ib protein complex(GO:0032398)
0.5	4.4	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.5	57.4	GO:0001669	acrosomal vesicle(GO:0001669)
0.5	1.4	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
0.5	8.1	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.5	23.5	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.5	1.9	GO:0097451	glial limiting end-foot(GO:0097451)
0.5	3.3	GO:0033263	CORVET complex(GO:0033263)
0.5	3.3	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.5	4.7	GO:0000800	lateral element(GO:0000800)
0.5	28.8	GO:0000786	nucleosome(GO:0000786)
0.5	32.4	GO:0043198	dendritic shaft(GO:0043198)
0.5	3.6	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.5	135.9	GO:0009897	external side of plasma membrane(GO:0009897)
0.5	23.6	GO:0031519	PcG protein complex(GO:0031519)
0.4	1.8	GO:0033553	rDNA heterochromatin(GO:0033553)
0.4	3.9	GO:0000439	core TFIIH complex(GO:0000439)
0.4	4.7	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.4	5.2	GO:0097542	ciliary tip(GO:0097542)
0.4	4.3	GO:0000346	transcription export complex(GO:0000346)
0.4	41.1	GO:0016605	PML body(GO:0016605)
0.4	4.5	GO:0042613	MHC class II protein complex(GO:0042613)
0.4	2.9	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.4	7.7	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.4	1.6	GO:0072487	MSL complex(GO:0072487)
0.4	0.8	GO:0099522	region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.4	18.7	GO:0005637	nuclear inner membrane(GO:0005637)
0.4	2.7	GO:0043202	lysosomal lumen(GO:0043202)
0.4	3.5	GO:0043020	NADPH oxidase complex(GO:0043020)
0.4	9.5	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.4	22.4	GO:0005643	nuclear pore(GO:0005643)
0.4	2.6	GO:0005915	zonula adherens(GO:0005915)
0.4	2.5	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.4	1.8	GO:0070461	SAGA-type complex(GO:0070461)
0.4	14.1	GO:0036064	ciliary basal body(GO:0036064)
0.4	29.3	GO:0005814	centriole(GO:0005814)
0.4	16.0	GO:0030286	dynein complex(GO:0030286)
0.4	1.1	GO:0005668	RNA polymerase transcription factor SL1 complex(GO:0005668)
0.4	4.9	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.4	6.4	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.4	23.2	GO:0005875	microtubule associated complex(GO:0005875)
0.3	1.6	GO:0044530	supraspliceosomal complex(GO:0044530)
0.3	1.2	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.3	15.2	GO:0034707	chloride channel complex(GO:0034707)
0.3	16.4	GO:0016234	inclusion body(GO:0016234)
0.3	5.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.3	1.5	GO:0048179	activin receptor complex(GO:0048179)
0.3	3.8	GO:0030914	STAGA complex(GO:0030914)
0.3	14.9	GO:0008023	transcription elongation factor complex(GO:0008023)
0.3	4.3	GO:0031528	microvillus membrane(GO:0031528)
0.3	1.1	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.3	0.5	GO:1990590	ATF1-ATF4 transcription factor complex(GO:1990590)
0.3	1.6	GO:0090568	nuclear transcriptional repressor complex(GO:0090568)
0.3	1.6	GO:0000124	SAGA complex(GO:0000124)
0.3	2.6	GO:0033270	paranode region of axon(GO:0033270)
0.3	5.2	GO:0042629	mast cell granule(GO:0042629)
0.3	21.9	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.3	3.3	GO:0044666	MLL3/4 complex(GO:0044666)
0.2	0.7	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.2	0.7	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.2	2.7	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.2	5.9	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.2	1.8	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.2	1.1	GO:0030891	VCB complex(GO:0030891)
0.2	3.7	GO:0030904	retromer complex(GO:0030904)
0.2	0.6	GO:0005592	collagen type XI trimer(GO:0005592)
0.2	13.0	GO:0000776	kinetochore(GO:0000776)
0.2	25.6	GO:0044798	nuclear transcription factor complex(GO:0044798)
0.2	13.9	GO:0016363	nuclear matrix(GO:0016363)
0.2	8.7	GO:0005657	replication fork(GO:0005657)
0.2	9.4	GO:0000118	histone deacetylase complex(GO:0000118)
0.2	4.6	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287)
0.2	2.6	GO:0051233	spindle midzone(GO:0051233)
0.2	4.7	GO:0060077	inhibitory synapse(GO:0060077)
0.2	2.5	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2	9.0	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.2	3.8	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2	3.0	GO:0032839	dendrite cytoplasm(GO:0032839)
0.2	49.9	GO:0005813	centrosome(GO:0005813)
0.2	1.7	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.2	1.4	GO:0031209	SCAR complex(GO:0031209)
0.2	0.7	GO:0005652	lamin filament(GO:0005638) nuclear lamina(GO:0005652)
0.2	0.3	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.2	29.2	GO:0000790	nuclear chromatin(GO:0000790)
0.2	2.1	GO:0001891	phagocytic cup(GO:0001891)
0.1	8.9	GO:0030496	midbody(GO:0030496)
0.1	1.4	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.1	1.1	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1	2.3	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1	0.8	GO:0031083	BLOC-1 complex(GO:0031083)
0.1	0.7	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.1	0.4	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.1	12.5	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1	13.2	GO:0005802	trans-Golgi network(GO:0005802)
0.1	3.6	GO:0030136	clathrin-coated vesicle(GO:0030136)
0.1	1.0	GO:0035631	CD40 receptor complex(GO:0035631)
0.1	0.3	GO:0097427	microtubule bundle(GO:0097427)
0.1	3.5	GO:0097014	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1	0.6	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.7	GO:0016272	prefoldin complex(GO:0016272)
0.1	3.4	GO:0005776	autophagosome(GO:0005776)
0.1	0.9	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.1	0.4	GO:0071817	MMXD complex(GO:0071817) CIA complex(GO:0097361)
0.1	0.5	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1	0.2	GO:0005594	collagen type IX trimer(GO:0005594)
0.1	3.7	GO:0031514	motile cilium(GO:0031514)
0.1	2.5	GO:0034708	methyltransferase complex(GO:0034708)
0.1	0.6	GO:0008385	IkappaB kinase complex(GO:0008385)
0.1	1.1	GO:0000145	exocyst(GO:0000145)
0.1	0.8	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	1.0	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	3.0	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	0.5	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	0.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.4	GO:0019028	viral capsid(GO:0019028)
0.0	0.8	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
22.3	66.8	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
7.9	23.7	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
6.7	33.7	GO:0004008	copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
6.4	32.0	GO:0043120	tumor necrosis factor binding(GO:0043120)
5.6	16.8	GO:0050294	steroid sulfotransferase activity(GO:0050294)
5.3	21.0	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
5.0	15.1	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
5.0	20.0	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
4.8	14.5	GO:0004040	amidase activity(GO:0004040)
4.8	48.0	GO:0051959	dynein light intermediate chain binding(GO:0051959)
4.4	26.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
4.3	17.2	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
4.1	49.2	GO:0015245	fatty acid transporter activity(GO:0015245)
4.0	16.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
3.9	11.8	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
3.9	23.5	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
3.9	11.7	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
3.9	11.6	GO:0031893	vasopressin receptor binding(GO:0031893)
3.8	7.6	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
3.8	15.1	GO:0061665	SUMO ligase activity(GO:0061665)
3.7	11.2	GO:0034040	lipid-transporting ATPase activity(GO:0034040) sterol-transporting ATPase activity(GO:0034041) glycoprotein transporter activity(GO:0034437)
3.7	18.5	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
3.6	32.6	GO:0032050	clathrin heavy chain binding(GO:0032050)
3.6	14.5	GO:0045159	myosin II binding(GO:0045159)
3.6	17.9	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
3.3	36.6	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
3.3	13.3	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
3.3	9.9	GO:0042498	diacyl lipopeptide binding(GO:0042498)
3.2	44.9	GO:0005243	gap junction channel activity(GO:0005243)
3.2	18.9	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
3.0	8.9	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
2.9	29.3	GO:0019957	C-C chemokine binding(GO:0019957)
2.9	11.7	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
2.9	14.6	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
2.9	8.7	GO:0070401	NADP+ binding(GO:0070401)
2.9	8.6	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
2.8	8.5	GO:0098603	selenol Se-methyltransferase activity(GO:0098603)
2.8	16.9	GO:0070567	cytidylyltransferase activity(GO:0070567)
2.7	16.4	GO:0051434	BH3 domain binding(GO:0051434)
2.7	8.2	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
2.7	19.0	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
2.7	56.5	GO:0023026	MHC class II protein complex binding(GO:0023026)
2.7	18.6	GO:1903136	cuprous ion binding(GO:1903136)
2.6	31.5	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
2.6	18.2	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
2.6	70.2	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
2.5	7.4	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
2.5	9.9	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
2.4	7.2	GO:0001716	L-amino-acid oxidase activity(GO:0001716)
2.4	16.7	GO:0004064	arylesterase activity(GO:0004064)
2.4	18.9	GO:0019871	sodium channel inhibitor activity(GO:0019871)
2.3	16.2	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
2.3	9.2	GO:0001635	calcitonin gene-related peptide receptor activity(GO:0001635)
2.3	31.6	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
2.2	71.7	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
2.2	10.9	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
2.2	8.7	GO:0001642	group III metabotropic glutamate receptor activity(GO:0001642)
2.2	26.0	GO:0034987	immunoglobulin receptor binding(GO:0034987)
2.1	32.2	GO:0045295	gamma-catenin binding(GO:0045295)
2.1	8.5	GO:0010997	anaphase-promoting complex binding(GO:0010997)
2.0	16.3	GO:0004966	galanin receptor activity(GO:0004966)
2.0	27.7	GO:0016208	AMP binding(GO:0016208)
2.0	4.0	GO:0009378	four-way junction helicase activity(GO:0009378)
2.0	41.2	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
2.0	9.8	GO:0004920	interleukin-10 receptor activity(GO:0004920)
1.9	105.2	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
1.9	9.6	GO:0005550	pheromone binding(GO:0005550)
1.9	11.3	GO:0004126	cytidine deaminase activity(GO:0004126)
1.9	54.7	GO:0052866	phosphatidylinositol phosphate phosphatase activity(GO:0052866)
1.9	3.8	GO:0070012	oligopeptidase activity(GO:0070012)
1.8	14.6	GO:0046870	cadmium ion binding(GO:0046870)
1.8	30.7	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
1.8	10.8	GO:0003840	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
1.8	14.2	GO:0005000	vasopressin receptor activity(GO:0005000)
1.8	8.8	GO:0004351	glutamate decarboxylase activity(GO:0004351)
1.8	5.3	GO:0070735	protein-glycine ligase activity(GO:0070735)
1.8	8.8	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
1.7	387.4	GO:0004252	serine-type endopeptidase activity(GO:0004252)
1.7	10.4	GO:0070051	fibrinogen binding(GO:0070051)
1.7	17.3	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
1.7	5.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
1.7	5.1	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
1.7	6.7	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
1.6	6.5	GO:0004967	glucagon receptor activity(GO:0004967)
1.6	4.9	GO:0015234	thiamine transmembrane transporter activity(GO:0015234) uptake transmembrane transporter activity(GO:0015563)
1.6	8.1	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
1.6	22.2	GO:0045499	chemorepellent activity(GO:0045499)
1.6	7.8	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
1.6	4.7	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
1.6	4.7	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
1.5	12.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
1.5	16.4	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
1.5	10.4	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
1.5	14.8	GO:0003680	AT DNA binding(GO:0003680)
1.5	13.2	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
1.5	5.9	GO:0016428	tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
1.4	4.3	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
1.4	13.0	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
1.4	8.6	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.4	14.4	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
1.4	5.7	GO:0003839	gamma-glutamylcyclotransferase activity(GO:0003839)
1.4	18.5	GO:0047372	acylglycerol lipase activity(GO:0047372)
1.4	7.1	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
1.4	7.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
1.4	4.2	GO:0016263	glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
1.4	16.9	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
1.4	5.6	GO:0016492	G-protein coupled neurotensin receptor activity(GO:0016492)
1.4	8.2	GO:0034647	histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
1.3	5.4	GO:0034584	piRNA binding(GO:0034584)
1.3	14.7	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
1.3	2.7	GO:0005131	growth hormone receptor binding(GO:0005131)
1.3	47.1	GO:0042169	SH2 domain binding(GO:0042169)
1.3	14.4	GO:0051011	microtubule minus-end binding(GO:0051011)
1.3	10.4	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
1.3	52.5	GO:0005109	frizzled binding(GO:0005109)
1.2	2.5	GO:0004963	follicle-stimulating hormone receptor activity(GO:0004963)
1.2	16.2	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
1.2	13.4	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
1.2	16.9	GO:0043274	phospholipase binding(GO:0043274)
1.2	8.5	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
1.2	4.8	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
1.2	3.5	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
1.2	16.4	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
1.2	7.0	GO:0004994	somatostatin receptor activity(GO:0004994)
1.2	11.6	GO:0036310	annealing helicase activity(GO:0036310)
1.2	8.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
1.2	3.5	GO:0009384	N-acylmannosamine kinase activity(GO:0009384)
1.2	5.8	GO:0008503	benzodiazepine receptor activity(GO:0008503)
1.1	21.6	GO:0017056	structural constituent of nuclear pore(GO:0017056)
1.1	15.9	GO:0051378	serotonin binding(GO:0051378)
1.1	7.9	GO:0071532	ankyrin repeat binding(GO:0071532)
1.1	68.2	GO:0019894	kinesin binding(GO:0019894)
1.1	8.9	GO:0016936	galactoside binding(GO:0016936)
1.1	5.6	GO:0032554	purine deoxyribonucleotide binding(GO:0032554)
1.1	4.4	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.1	6.5	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
1.1	6.5	GO:0032051	clathrin light chain binding(GO:0032051)
1.1	22.6	GO:0005212	structural constituent of eye lens(GO:0005212)
1.1	3.2	GO:0004874	aryl hydrocarbon receptor activity(GO:0004874)
1.1	14.7	GO:0015250	water channel activity(GO:0015250)
1.1	2.1	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
1.0	3.1	GO:0004586	ornithine decarboxylase activity(GO:0004586)
1.0	6.2	GO:0008865	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
1.0	12.4	GO:0019911	structural constituent of myelin sheath(GO:0019911)
1.0	3.1	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
1.0	5.9	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
1.0	17.4	GO:0005522	profilin binding(GO:0005522)
1.0	3.8	GO:0015350	methotrexate transporter activity(GO:0015350)
0.9	5.5	GO:0033142	progesterone receptor binding(GO:0033142)
0.9	35.0	GO:0004364	glutathione transferase activity(GO:0004364)
0.9	2.7	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.9	8.8	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.9	4.4	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.9	7.0	GO:0008172	S-methyltransferase activity(GO:0008172)
0.9	5.2	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.8	6.8	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.8	1.7	GO:0097677	STAT family protein binding(GO:0097677)
0.8	3.3	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
0.8	27.2	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.8	32.7	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.8	3.3	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733)
0.8	16.3	GO:0008236	serine-type peptidase activity(GO:0008236)
0.8	22.5	GO:0008536	Ran GTPase binding(GO:0008536)
0.8	17.5	GO:0004623	phospholipase A2 activity(GO:0004623)
0.8	11.8	GO:0004806	triglyceride lipase activity(GO:0004806)
0.8	7.0	GO:0042285	xylosyltransferase activity(GO:0042285)
0.8	22.7	GO:0008392	arachidonic acid epoxygenase activity(GO:0008392)
0.7	11.7	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.7	2.9	GO:0017089	glycolipid transporter activity(GO:0017089)
0.7	2.9	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.7	2.9	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.7	2.2	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.7	2.9	GO:1990254	keratin filament binding(GO:1990254)
0.7	13.7	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.7	2.2	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.7	10.7	GO:0043522	leucine zipper domain binding(GO:0043522)
0.7	14.7	GO:0042288	MHC class I protein binding(GO:0042288)
0.7	3.5	GO:0005111	type 1 fibroblast growth factor receptor binding(GO:0005105) type 2 fibroblast growth factor receptor binding(GO:0005111)
0.7	2.1	GO:1990460	leptin receptor binding(GO:1990460)
0.7	7.5	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.7	2.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.7	2.7	GO:0052794	exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.7	4.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.7	7.4	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.7	4.0	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.7	13.9	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.7	5.9	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.7	7.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.7	5.9	GO:0005113	patched binding(GO:0005113)
0.6	11.0	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.6	7.6	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.6	3.8	GO:0008494	translation activator activity(GO:0008494)
0.6	3.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.6	2.5	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.6	1.8	GO:0038100	nodal binding(GO:0038100)
0.6	3.7	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.6	4.3	GO:0004385	guanylate kinase activity(GO:0004385)
0.6	4.2	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.6	2.4	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.6	5.3	GO:0001727	lipid kinase activity(GO:0001727)
0.6	2.3	GO:0060229	phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.6	4.6	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
0.6	5.2	GO:0034056	estrogen response element binding(GO:0034056)
0.6	2.9	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.6	2.8	GO:0090555	phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.6	1.7	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.5	4.9	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.5	13.1	GO:0070840	dynein complex binding(GO:0070840)
0.5	1.6	GO:0005135	interleukin-3 receptor binding(GO:0005135)
0.5	2.2	GO:0005136	interleukin-4 receptor binding(GO:0005136)
0.5	2.2	GO:0000829	inositol heptakisphosphate kinase activity(GO:0000829)
0.5	40.2	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.5	11.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.5	5.0	GO:0070628	proteasome binding(GO:0070628)
0.5	3.0	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.5	13.5	GO:0008483	transaminase activity(GO:0008483)
0.5	1.9	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.5	1.9	GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.5	4.7	GO:0016505	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) peptidase activator activity involved in apoptotic process(GO:0016505)
0.5	12.7	GO:0004407	histone deacetylase activity(GO:0004407)
0.5	8.4	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.5	8.8	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.5	52.7	GO:0002020	protease binding(GO:0002020)
0.5	9.6	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.5	1.4	GO:0031493	nucleosomal histone binding(GO:0031493)
0.5	13.8	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.5	2.7	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.4	15.6	GO:0016417	S-acyltransferase activity(GO:0016417)
0.4	14.7	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.4	12.3	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.4	4.8	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.4	0.9	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
0.4	3.0	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.4	4.3	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.4	2.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.4	4.2	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.4	4.6	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.4	3.3	GO:0003996	acyl-CoA ligase activity(GO:0003996)
0.4	3.3	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.4	2.8	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.4	5.5	GO:0008329	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.4	3.5	GO:0043995	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.4	4.7	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.4	28.8	GO:0003777	microtubule motor activity(GO:0003777)
0.4	1.1	GO:0070506	high-density lipoprotein particle receptor activity(GO:0070506)
0.4	1.9	GO:0004977	melanocortin receptor activity(GO:0004977)
0.4	2.6	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.4	1.1	GO:0030626	U12 snRNA binding(GO:0030626)
0.4	5.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.4	10.0	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.4	2.8	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.4	1.1	GO:0030977	taurine binding(GO:0030977)
0.3	1.0	GO:0001069	regulatory region RNA binding(GO:0001069)
0.3	8.2	GO:0000030	mannosyltransferase activity(GO:0000030)
0.3	9.9	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3	0.6	GO:0035325	Toll-like receptor binding(GO:0035325)
0.3	8.1	GO:0070330	aromatase activity(GO:0070330)
0.3	1.0	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.3	6.9	GO:0003746	translation elongation factor activity(GO:0003746)
0.3	1.9	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.3	4.0	GO:0019213	deacetylase activity(GO:0019213)
0.3	17.5	GO:0051213	dioxygenase activity(GO:0051213)
0.3	4.6	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.3	3.4	GO:0008097	5S rRNA binding(GO:0008097)
0.3	13.4	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.3	1.7	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.3	1.7	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.3	1.9	GO:0008308	voltage-gated anion channel activity(GO:0008308)
0.3	2.5	GO:0070492	oligosaccharide binding(GO:0070492)
0.3	11.3	GO:0008146	sulfotransferase activity(GO:0008146)
0.3	1.9	GO:0004630	phospholipase D activity(GO:0004630)
0.3	5.4	GO:0008327	methyl-CpG binding(GO:0008327)
0.3	4.6	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.3	2.1	GO:0043515	kinetochore binding(GO:0043515)
0.3	9.3	GO:0030544	Hsp70 protein binding(GO:0030544)
0.3	14.0	GO:0033613	activating transcription factor binding(GO:0033613)
0.3	1.3	GO:0019770	IgG receptor activity(GO:0019770)
0.3	0.8	GO:0032810	sterol response element binding(GO:0032810)
0.3	24.7	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.3	1.8	GO:0003896	DNA primase activity(GO:0003896)
0.2	4.2	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.2	3.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.2	2.7	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.2	4.4	GO:0001848	complement binding(GO:0001848)
0.2	11.1	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.2	11.8	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2	0.7	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.2	2.4	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.2	2.1	GO:0004622	lysophospholipase activity(GO:0004622)
0.2	3.0	GO:0003796	lysozyme activity(GO:0003796)
0.2	6.0	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.2	1.4	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.2	3.6	GO:0015643	toxic substance binding(GO:0015643)
0.2	1.7	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2	8.6	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2	0.4	GO:0042015	interleukin-20 binding(GO:0042015)
0.2	2.2	GO:0004579	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2	15.3	GO:0008565	protein transporter activity(GO:0008565)
0.2	1.0	GO:0048495	Roundabout binding(GO:0048495)
0.2	0.6	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
0.2	4.2	GO:0004890	GABA-A receptor activity(GO:0004890)
0.2	0.7	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.2	8.3	GO:0043621	protein self-association(GO:0043621)
0.2	4.3	GO:0042162	telomeric DNA binding(GO:0042162)
0.2	1.6	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.2	8.9	GO:0035064	methylated histone binding(GO:0035064)
0.2	2.9	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.2	2.9	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.2	1.6	GO:0019808	polyamine binding(GO:0019808)
0.2	1.0	GO:0098634	protein binding involved in cell-matrix adhesion(GO:0098634)
0.2	16.9	GO:0017124	SH3 domain binding(GO:0017124)
0.2	0.3	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2	1.9	GO:0017091	AU-rich element binding(GO:0017091)
0.2	0.9	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.2	0.3	GO:0061733	peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.1	0.4	GO:0046790	virion binding(GO:0046790)
0.1	8.7	GO:0003743	translation initiation factor activity(GO:0003743)
0.1	3.8	GO:0008188	neuropeptide receptor activity(GO:0008188)
0.1	0.9	GO:0097200	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1	0.7	GO:0008502	melatonin receptor activity(GO:0008502)
0.1	0.5	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.1	0.5	GO:0015056	corticotrophin-releasing factor receptor activity(GO:0015056) corticotropin-releasing hormone receptor activity(GO:0043404)
0.1	0.9	GO:1990405	protein antigen binding(GO:1990405)
0.1	0.9	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.1	0.8	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.1	2.7	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.1	0.4	GO:0031531	thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1	0.8	GO:0031748	D1 dopamine receptor binding(GO:0031748)
0.1	3.9	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	0.3	GO:0004478	methionine adenosyltransferase activity(GO:0004478)
0.1	2.6	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.9	GO:1990446	U1 snRNP binding(GO:1990446)
0.1	0.7	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	1.6	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	0.7	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.1	17.4	GO:0044822	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1	0.9	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1	3.6	GO:0030551	cyclic nucleotide binding(GO:0030551)
0.1	5.7	GO:0008026	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.1	5.2	GO:0003725	double-stranded RNA binding(GO:0003725)
0.1	4.6	GO:0003684	damaged DNA binding(GO:0003684)
0.1	0.2	GO:0002114	interleukin-33 receptor activity(GO:0002114)
0.1	1.2	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.1	1.0	GO:0019789	SUMO transferase activity(GO:0019789)
0.1	1.2	GO:0001056	RNA polymerase III activity(GO:0001056)
0.1	1.4	GO:0004532	exoribonuclease activity(GO:0004532)
0.1	1.8	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1	0.4	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	3.3	GO:0004540	ribonuclease activity(GO:0004540)
0.1	3.8	GO:0008170	N-methyltransferase activity(GO:0008170)
0.1	0.8	GO:0031369	translation initiation factor binding(GO:0031369)
0.1	2.0	GO:0042605	peptide antigen binding(GO:0042605)
0.1	0.3	GO:0030280	structural constituent of epidermis(GO:0030280)
0.1	1.5	GO:0070001	aspartic-type peptidase activity(GO:0070001)
0.0	3.4	GO:0051082	unfolded protein binding(GO:0051082)
0.0	0.3	GO:0051998	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.7	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.2	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.5	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.5	GO:0005537	mannose binding(GO:0005537)
0.0	0.1	GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483) mRNA methyltransferase activity(GO:0008174)
0.0	0.2	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.5	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.2	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.3	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.2	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	1.7	GO:0005125	cytokine activity(GO:0005125)
0.0	0.1	GO:0102338	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.8	52.6	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
3.6	188.3	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
3.1	39.7	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
2.9	50.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
2.2	146.4	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
1.9	3.8	PID ERBB4 PATHWAY	ErbB4 signaling events
1.5	12.3	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
1.5	22.8	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
1.4	28.8	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
1.4	55.3	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
1.4	14.9	PID S1P S1P4 PATHWAY	S1P4 pathway
1.1	11.0	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
1.1	13.1	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.9	55.8	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.9	17.7	PID AURORA A PATHWAY	Aurora A signaling
0.9	13.9	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.9	21.6	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.8	17.5	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.8	29.6	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.8	19.7	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.8	13.0	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.8	44.9	PID TNF PATHWAY	TNF receptor signaling pathway
0.8	5.6	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.8	40.2	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.7	33.6	PID PLK1 PATHWAY	PLK1 signaling events
0.7	5.4	ST GAQ PATHWAY	G alpha q Pathway
0.7	16.4	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.6	7.6	PID EPO PATHWAY	EPO signaling pathway
0.6	17.7	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.6	27.7	PID AURORA B PATHWAY	Aurora B signaling
0.6	14.5	PID BCR 5PATHWAY	BCR signaling pathway
0.6	14.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.6	11.5	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.6	47.7	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.5	8.3	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.5	14.5	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.5	4.5	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.5	4.4	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.5	17.2	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.5	10.6	PID P73PATHWAY	p73 transcription factor network
0.5	6.1	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.5	13.3	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.4	5.8	PID ATR PATHWAY	ATR signaling pathway
0.4	6.3	PID EPHA FWDPATHWAY	EPHA forward signaling
0.4	13.4	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.4	4.4	PID REELIN PATHWAY	Reelin signaling pathway
0.4	15.9	PID CDC42 PATHWAY	CDC42 signaling events
0.4	7.7	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.4	7.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.4	18.0	PID FANCONI PATHWAY	Fanconi anemia pathway
0.4	8.1	PID ILK PATHWAY	Integrin-linked kinase signaling
0.4	11.4	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.4	9.7	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.4	5.9	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.3	4.9	PID IL1 PATHWAY	IL1-mediated signaling events
0.3	1.6	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.3	9.5	PID IL12 2PATHWAY	IL12-mediated signaling events
0.2	5.4	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.2	4.0	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.2	3.2	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.2	3.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.2	4.6	PID MTOR 4PATHWAY	mTOR signaling pathway
0.2	2.6	PID ARF6 PATHWAY	Arf6 signaling events
0.1	5.1	PID P53 REGULATION PATHWAY	p53 pathway
0.1	3.7	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	1.3	PID ALK2 PATHWAY	ALK2 signaling events
0.1	0.7	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	4.2	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	1.7	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.1	1.5	PID RAC1 PATHWAY	RAC1 signaling pathway
0.1	3.4	PID E2F PATHWAY	E2F transcription factor network
0.1	1.3	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	20.6	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	2.3	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.1	0.5	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.2	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.5	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.6	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.2	91.9	REACTOME DEFENSINS	Genes involved in Defensins
6.8	47.4	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
4.8	53.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
4.3	8.5	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
3.8	69.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
3.3	59.9	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
2.8	48.4	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
2.6	25.9	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
2.5	17.5	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
2.4	108.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
2.2	26.8	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
2.2	6.5	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
1.9	32.3	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
1.9	22.5	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
1.8	7.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
1.8	23.5	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
1.8	21.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
1.5	54.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
1.4	23.2	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
1.4	23.0	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
1.4	38.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
1.4	50.3	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
1.4	24.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
1.4	17.8	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
1.3	13.4	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
1.3	6.7	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
1.3	7.9	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
1.2	14.7	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
1.1	21.7	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
1.1	15.9	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
1.1	7.9	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
1.1	29.7	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
1.0	19.9	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
1.0	9.3	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
1.0	48.5	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
1.0	48.4	REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT	Genes involved in Lipid digestion, mobilization, and transport
1.0	23.0	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
1.0	17.9	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.9	13.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.9	4.3	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.9	9.4	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.8	6.7	REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX	Genes involved in Assembly of the pre-replicative complex
0.8	13.5	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.8	17.7	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.8	23.6	REACTOME KINESINS	Genes involved in Kinesins
0.7	5.9	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.7	5.1	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.7	9.9	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.7	51.9	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.7	15.9	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.7	11.4	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.7	10.0	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.7	7.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.6	23.2	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.6	15.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.6	38.0	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.6	12.6	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.6	40.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.6	8.4	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.6	32.2	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.6	3.4	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.5	2.7	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.5	3.7	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.5	6.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.5	6.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.5	22.4	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.5	10.1	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.5	13.2	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.5	8.6	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.5	10.8	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.4	12.1	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.4	6.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.4	9.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.4	3.3	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.4	4.4	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.4	2.2	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.4	5.8	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.3	3.8	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.3	4.0	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.3	5.6	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.3	7.6	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.3	7.2	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.3	39.5	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.3	10.7	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.3	5.7	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.3	3.8	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.3	10.2	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.3	16.3	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.3	3.0	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.3	12.8	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.3	14.1	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.3	3.1	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.3	5.3	REACTOME GLOBAL GENOMIC NER GG NER	Genes involved in Global Genomic NER (GG-NER)
0.3	5.4	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.3	4.3	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3	2.6	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.3	12.9	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.2	3.6	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.2	2.7	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.2	0.8	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2	3.4	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.2	5.8	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.2	2.6	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.2	2.2	REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.2	1.1	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.2	5.8	REACTOME AMYLOIDS	Genes involved in Amyloids
0.2	1.7	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	3.4	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	1.5	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.1	1.0	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1	2.5	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	1.4	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	2.5	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.1	0.6	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	1.5	REACTOME DEADENYLATION DEPENDENT MRNA DECAY	Genes involved in Deadenylation-dependent mRNA decay
0.1	22.5	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1	1.7	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	1.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	0.7	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1	0.6	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.1	1.9	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1	1.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	2.2	REACTOME SIGNALING BY ILS	Genes involved in Signaling by Interleukins
0.0	2.4	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.5	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.4	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	3.1	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.4	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors

Results for Tcf4_Mesp1

Z-value: 2.15

Motif logo

Transcription factors associated with Tcf4_Mesp1

Activity-expression correlation:

Activity profile of Tcf4_Mesp1 motif

Sorted Z-values of Tcf4_Mesp1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tcf4_Mesp1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: