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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Tbx19

Z-value: 0.94

Motif logo

Transcription factors associated with Tbx19

Gene Symbol Gene ID Gene Info
ENSRNOG00000002979 T-box 19

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tbx19rn6_v1_chr13_-_83425641_83425641-0.283.5e-07Click!

Activity profile of Tbx19 motif

Sorted Z-values of Tbx19 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_108717309 53.12 ENSRNOT00000085062

chr16_+_68633720 33.05 ENSRNOT00000081838
sperm motility kinase-like
chr2_-_21437193 21.76 ENSRNOT00000084002
creatine kinase, mitochondrial 2
chr2_-_19808937 20.05 ENSRNOT00000044237
ATPase H+ transporting accessory protein 1 like
chr1_+_105349069 19.82 ENSRNOT00000056030
neural EGFL like 1
chr9_-_65879521 19.57 ENSRNOT00000017517
amyotrophic lateral sclerosis 2 chromosome region, candidate 11
chr7_+_27620458 19.29 ENSRNOT00000059532
similar to FLJ25323 protein
chr19_-_56633633 19.10 ENSRNOT00000023911
centriole, cilia and spindle-associated protein
chr6_+_48452369 18.22 ENSRNOT00000044310
myelin transcription factor 1-like
chr19_+_49016891 18.01 ENSRNOT00000016713
dynein light chain roadblock-type 2
chr18_-_786674 17.99 ENSRNOT00000021955
centrin 1
chr3_-_176644951 17.15 ENSRNOT00000049961
potassium voltage-gated channel subfamily Q member 2
chr8_+_29453643 16.33 ENSRNOT00000090643
opioid binding protein/cell adhesion molecule-like
chr2_+_207262934 15.88 ENSRNOT00000016833
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr1_-_81881549 15.86 ENSRNOT00000027497
ATPase Na+/K+ transporting subunit alpha 3
chr4_+_21317695 15.77 ENSRNOT00000007572
glutamate metabotropic receptor 3
chr1_-_195096694 15.54 ENSRNOT00000088874
SNRPN upstream reading frame
chr3_-_44086006 15.53 ENSRNOT00000034449
ENSRNOT00000082604
ermin
chr10_-_107539658 15.24 ENSRNOT00000089346
RNA binding protein, fox-1 homolog 3
chr16_-_54628458 15.18 ENSRNOT00000042587
ADAM metallopeptidase domain 24
chr7_-_82687130 15.07 ENSRNOT00000006791
transmembrane protein 74
chr5_+_8459660 14.83 ENSRNOT00000007491
carboxypeptidase A6
chrX_+_118197217 14.16 ENSRNOT00000090922
5-hydroxytryptamine receptor 2C
chr9_-_46401911 13.75 ENSRNOT00000046557
cellular repressor of E1A-stimulated genes 2
chr16_+_34795971 13.33 ENSRNOT00000043510
myeloid-associated differentiation marker-like
chr3_+_143151739 13.27 ENSRNOT00000006850
cystatin 13
chr1_-_260341723 13.23 ENSRNOT00000030656
oligodendrocytic myelin paranodal and inner loop protein
chr10_+_110631494 13.20 ENSRNOT00000054915
fructosamine 3 kinase
chr7_-_107223047 12.45 ENSRNOT00000007250
ENSRNOT00000084875
leucine rich repeat containing 6
chr1_-_91526570 12.04 ENSRNOT00000056583
WD repeat domain 88
chr1_-_227457629 11.55 ENSRNOT00000035910
ENSRNOT00000073770
membrane spanning 4-domains A5
chr13_-_47154292 11.55 ENSRNOT00000005284
CD55 molecule, decay accelerating factor for complement
chr2_-_123407496 11.29 ENSRNOT00000080207
transient receptor potential cation channel, subfamily C, member 3
chr10_-_107539465 11.24 ENSRNOT00000004524
RNA binding protein, fox-1 homolog 3
chr20_+_20259254 11.11 ENSRNOT00000085985
ENSRNOT00000077620
ENSRNOT00000090273
ankyrin 3
chr10_+_11240138 10.91 ENSRNOT00000048687
sarcalumenin
chrX_+_125314613 10.83 ENSRNOT00000029193
hypothetical protein LOC691215
chr16_-_20939545 10.79 ENSRNOT00000027457
SURP and G patch domain containing 2
chr6_+_29518416 10.39 ENSRNOT00000078660

chr3_+_86621205 10.34 ENSRNOT00000044595
leucine rich repeat containing 4C
chr10_+_72486152 10.29 ENSRNOT00000004193
similar to Chromodomain-helicase-DNA-binding protein 1 (CHD-1)
chr16_+_81204766 9.78 ENSRNOT00000042465
transmembrane protein 255B
chr9_+_6966908 9.71 ENSRNOT00000072796
ST6 beta-galactoside alpha-2,6-sialyltransferase 2
chr14_-_28536260 9.26 ENSRNOT00000059942
adhesion G protein-coupled receptor L3
chrX_-_121066855 9.24 ENSRNOT00000044165
testis derived transcript-like
chr16_-_12662336 9.00 ENSRNOT00000080161
similar to hypothetical protein 4930474N05
chr2_-_250805445 8.89 ENSRNOT00000055362
chloride channel calcium activated 4-like
chr3_+_122928964 8.83 ENSRNOT00000074724
rCG26795-like
chr5_-_135472116 8.79 ENSRNOT00000022170
nuclear autoantigenic sperm protein
chr1_+_42170281 8.73 ENSRNOT00000092879
vasoactive intestinal peptide
chr13_-_6712734 8.66 ENSRNOT00000061683

chr9_+_8399632 8.53 ENSRNOT00000092165
hypothetical protein LOC100360856
chr10_+_10555337 8.32 ENSRNOT00000032495
similar to MGC45438 protein
chrX_+_110342718 8.24 ENSRNOT00000043861

chr3_+_113818872 8.20 ENSRNOT00000044158
cancer susceptibility candidate 4
chr3_+_176985900 8.00 ENSRNOT00000020210
abhydrolase domain containing 16B
chr1_-_67284864 7.96 ENSRNOT00000082908
similar to zinc finger and SCAN domain containing 4
chr1_+_222907159 7.93 ENSRNOT00000032123
HRAS-like suppressor family, member 5
chrX_+_97074710 7.88 ENSRNOT00000044379
similar to RIKEN cDNA 4921511C20 gene
chr1_+_67025240 7.69 ENSRNOT00000051024
vomeronasal 1 receptor 47
chr9_+_42871950 7.67 ENSRNOT00000089673
AT-rich interaction domain 5A
chr20_-_48503898 7.57 ENSRNOT00000073091
WAS protein family, member 1
chr16_+_9074033 7.54 ENSRNOT00000027193
family with sequence similarity 170, member B
chr1_+_42170583 7.53 ENSRNOT00000093104
vasoactive intestinal peptide
chr1_-_81412251 7.43 ENSRNOT00000026946
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr1_-_67065797 7.28 ENSRNOT00000048152
vomeronasal 1 receptor 46
chrX_-_17708388 7.26 ENSRNOT00000048887
similar to mgclh
chr9_-_115382445 7.24 ENSRNOT00000091316
protein tyrosine phosphatase, receptor type, M
chr2_-_212852870 7.20 ENSRNOT00000066218
netrin G1
chr5_+_154077944 7.05 ENSRNOT00000031512
interleukin 22 receptor subunit alpha 1
chr2_+_41157823 6.97 ENSRNOT00000066384
phosphodiesterase 4D
chr2_+_116970344 6.93 ENSRNOT00000039603
EGF-like and EMI domain containing 1
chr1_-_7322424 6.88 ENSRNOT00000066725
ENSRNOT00000081112
zinc finger, C2HC-type containing 1B
chr8_-_55491152 6.74 ENSRNOT00000014965
rCG58364-like
chr1_-_260460791 6.67 ENSRNOT00000018179
tolloid-like 2
chr6_+_28382962 6.63 ENSRNOT00000016976
proopiomelanocortin
chr8_-_48619592 6.61 ENSRNOT00000012534
ATP binding cassette subfamily G member 4
chr8_-_85712647 6.52 ENSRNOT00000000215
developmental pluripotency associated 5
chr17_-_66667853 6.50 ENSRNOT00000058749
ANKRD26-like family C, member 2
chr10_+_62981297 6.46 ENSRNOT00000031618
EF-hand calcium binding domain 5
chr13_+_77602249 6.44 ENSRNOT00000003407
ENSRNOT00000076589
tenascin R
chr13_+_50873605 6.40 ENSRNOT00000004382
fibromodulin
chr17_+_5342829 6.38 ENSRNOT00000079938
SPATA31 subfamily D, member 3
chr1_+_63734135 6.35 ENSRNOT00000084439
neutrophil immunoglobulin-like receptor-1
chr13_-_85695421 6.14 ENSRNOT00000005768
leucine rich repeat containing 52
chr1_-_82918444 6.08 ENSRNOT00000072555
CD177 antigen-like
chr2_+_198231291 6.04 ENSRNOT00000078288
ENSRNOT00000046739
OTU deubiquitinase 7B
chr3_+_104899682 5.94 ENSRNOT00000041910
formin 1
chr7_+_60087429 5.80 ENSRNOT00000073117
leucine-rich repeat-containing 10
chr15_-_2648294 5.78 ENSRNOT00000018462
voltage-dependent anion channel 2
chr9_+_66058047 5.76 ENSRNOT00000071819
cyclin-dependent kinase 15
chr1_-_260992291 5.73 ENSRNOT00000035415
ENSRNOT00000034758
slit guidance ligand 1
chr1_-_167165265 5.62 ENSRNOT00000027321
ring finger protein 121
chr14_-_77321783 5.45 ENSRNOT00000007154
Ly1 antibody reactive
chr14_-_86146744 5.45 ENSRNOT00000019335
myosin light chain 7
chr4_+_9882904 5.31 ENSRNOT00000016909
DnaJ heat shock protein family (Hsp40) member C2
chrX_-_106085878 5.27 ENSRNOT00000049735
preferentially expressed antigen in melanoma
chr11_-_1437732 5.24 ENSRNOT00000037345
casein kinase 2, alpha prime interacting protein
chr7_-_122926336 4.93 ENSRNOT00000000205
chondroadherin-like
chr14_-_77321977 4.88 ENSRNOT00000084093
Ly1 antibody reactive
chr1_-_82902975 4.86 ENSRNOT00000087563
CD177 antigen-like
chr1_+_89215266 4.69 ENSRNOT00000093612
ENSRNOT00000084799
dermokine
chrX_-_157848842 4.65 ENSRNOT00000035398
family with sequence similarity 122C
chr10_-_34990943 4.53 ENSRNOT00000075555
required for meiotic nuclear division 5 homolog B
chr2_-_183128932 4.44 ENSRNOT00000031179
meiotic nuclear divisions 1
chrX_+_90588124 4.44 ENSRNOT00000045685
TGFB-induced factor homeobox 2-like, X-linked 2
chr17_-_71897972 4.39 ENSRNOT00000065942
Scm-like with four mbt domains 2
chr18_+_30869628 4.33 ENSRNOT00000060470
protocadherin gamma subfamily B, 4
chr4_+_86275717 4.25 ENSRNOT00000016414
protein phosphatase 1, regulatory subunit 17
chr16_-_81434363 4.24 ENSRNOT00000080963
RAS p21 protein activator 3
chr7_+_27248115 4.23 ENSRNOT00000031946
ENSRNOT00000059545
first gene upstream of Nt5dc3
chr13_+_74456487 4.22 ENSRNOT00000065801
angiopoietin-like 1
chr17_+_60059949 4.16 ENSRNOT00000025458
membrane palmitoylated protein 7
chr7_+_126096793 4.10 ENSRNOT00000047234
ENSRNOT00000088042
fibulin 1
chr2_+_127770676 4.01 ENSRNOT00000068405
abhydrolase domain containing 18
chr9_-_30321323 3.85 ENSRNOT00000018234
family with sequence similarity 135, member A
chr19_+_37229120 3.81 ENSRNOT00000076335
heat shock transcription factor 4
chr1_+_63964155 3.74 ENSRNOT00000078512

chr17_+_18059382 3.72 ENSRNOT00000031656
NHL repeat containing E3 ubiquitin protein ligase 1
chr18_-_74198369 3.71 ENSRNOT00000073597
HAUS augmin-like complex subunit 1
chr15_-_46593653 3.60 ENSRNOT00000015021
BLK proto-oncogene, Src family tyrosine kinase
chr7_-_16068823 3.58 ENSRNOT00000073630
olfactory receptor 922
chr10_+_63677396 3.49 ENSRNOT00000005100
solute carrier family 43 member 2
chr3_+_133232432 3.48 ENSRNOT00000006412
NADH:ubiquinone oxidoreductase complex assembly factor 5
chr6_-_140587251 3.40 ENSRNOT00000090704

chrX_+_106360393 3.33 ENSRNOT00000004260
G protein-coupled receptor associated sorting protein 2
chr10_+_89166890 3.33 ENSRNOT00000088331
receptor activity modifying protein 2
chr10_+_89167146 3.32 ENSRNOT00000043953
receptor activity modifying protein 2
chr10_+_63776378 3.29 ENSRNOT00000084496
inositol polyphosphate-5-phosphatase K
chr15_+_51034620 3.25 ENSRNOT00000032826
NK2 homeobox 6
chr8_-_111101416 3.23 ENSRNOT00000084413
centrosomal protein 63
chr7_-_15301382 3.22 ENSRNOT00000081512
zinc finger protein 763
chr9_-_52401660 3.21 ENSRNOT00000049387
vomeronasal 1 receptor 50
chr16_-_74408030 3.19 ENSRNOT00000026418
solute carrier family 20 member 2
chr3_+_77414999 3.15 ENSRNOT00000047910
olfactory receptor 659
chr4_-_164691405 3.14 ENSRNOT00000090979
ENSRNOT00000091932
ENSRNOT00000078219
Ly49 stimulatory receptor 4
Ly49 inhibitory receptor 2
chr20_+_3351303 3.08 ENSRNOT00000080419
ENSRNOT00000001065
ENSRNOT00000086503
alpha tubulin acetyltransferase 1
chr16_+_20939655 3.00 ENSRNOT00000027550
armadillo repeat containing 6
chrX_+_156552528 2.96 ENSRNOT00000086429
testis expressed 28
chr1_+_69853553 2.86 ENSRNOT00000042086
zinc finger protein 954
chr7_-_114380613 2.85 ENSRNOT00000011898
argonaute 2, RISC catalytic component
chrX_+_128882366 2.80 ENSRNOT00000091479
TEX13 family member C2
chr16_+_73584521 2.78 ENSRNOT00000024301
GINS complex subunit 4
chr10_+_67427066 2.77 ENSRNOT00000035642
ATPase family, AAA domain containing 5
chr4_+_66090681 2.76 ENSRNOT00000078066
tetratricopeptide repeat domain 26
chr12_+_52630551 2.64 ENSRNOT00000072562

chrX_+_83926513 2.63 ENSRNOT00000035274
similar to RIKEN cDNA 2010106E10
chr12_+_40895515 2.59 ENSRNOT00000046323
protein tyrosine phosphatase, non-receptor type 11
chr18_+_3565166 2.55 ENSRNOT00000039377
RIO kinase 3
chr6_+_144071914 2.42 ENSRNOT00000056743
uncharacterized LOC102547216
chr11_-_23063414 2.42 ENSRNOT00000043396
olfactory receptor 6C6-like
chr7_+_5324469 2.41 ENSRNOT00000071164
olfactory receptor 901
chr6_+_137924568 2.40 ENSRNOT00000046456
metastasis associated 1
chr11_-_74793673 2.39 ENSRNOT00000002338
ENSRNOT00000002343
OPA1, mitochondrial dynamin like GTPase
chr16_+_53998560 2.38 ENSRNOT00000077188
ENSRNOT00000013463
N-acylsphingosine amidohydrolase 1
chr17_+_8558827 2.29 ENSRNOT00000016187
interleukin 9
chr14_+_48726045 2.25 ENSRNOT00000086646
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr9_-_117467198 2.18 ENSRNOT00000048323
similar to TDPOZ3
chr14_+_62309299 2.16 ENSRNOT00000048309
vomeronasal 1 receptor 26
chr4_-_55740627 2.13 ENSRNOT00000010658
paired box 4
chr2_+_4858907 2.12 ENSRNOT00000067201
ENSRNOT00000093305
olfactory receptor 204
chrX_-_35431164 2.04 ENSRNOT00000004968
sex comb on midleg-like 2 (Drosophila)
chr1_-_63457134 1.99 ENSRNOT00000083436

chr4_+_2055615 1.98 ENSRNOT00000007646
ring finger protein 32
chr4_-_119399130 1.97 ENSRNOT00000042796
vomeronasal 1 receptor 101
chr15_+_32060750 1.95 ENSRNOT00000084376

chr5_-_28131133 1.91 ENSRNOT00000067331
solute carrier family 26 member 7
chr14_+_85142279 1.86 ENSRNOT00000011281
THO complex 5
chr20_+_6356423 1.84 ENSRNOT00000000628
cyclin-dependent kinase inhibitor 1A
chr11_-_23058456 1.82 ENSRNOT00000073285
olfactory receptor 6C6-like
chr19_-_43391828 1.81 ENSRNOT00000023927
component of oligomeric golgi complex 4
chr1_-_227047290 1.81 ENSRNOT00000037226
membrane spanning 4-domains A15
chr8_+_20728817 1.77 ENSRNOT00000050101
olfactory receptor 1179
chr1_+_170242846 1.76 ENSRNOT00000023751
cyclic nucleotide gated channel alpha 4
chr1_+_71844368 1.75 ENSRNOT00000044754
vomeronasal 1 receptor 32
chr3_-_105214989 1.74 ENSRNOT00000037895
gremlin 1, DAN family BMP antagonist
chr3_+_73010786 1.69 ENSRNOT00000051010
olfactory receptor 447
chr1_+_73837944 1.65 ENSRNOT00000036413
leukocyte-associated immunoglobulin-like receptor 1
chr1_-_103631235 1.63 ENSRNOT00000072393
MAS-related GPR, member B13
chr1_+_248402980 1.62 ENSRNOT00000043517
coiled-coil-helix-coiled-coil-helix domain containing 4
chr2_+_88217188 1.59 ENSRNOT00000014267
carbonic anhydrase I
chr5_+_156615886 1.58 ENSRNOT00000076439
SH2 domain containing 5
chr17_+_76410585 1.55 ENSRNOT00000024016
cell division cycle 123
chr4_-_32087600 1.54 ENSRNOT00000013841
SEM1, 26S proteasome complex subunit
chr3_+_137154086 1.53 ENSRNOT00000034252
otoraplin
chr11_-_33760100 1.50 ENSRNOT00000065810
RGD1562683
chr8_-_17776361 1.50 ENSRNOT00000041855
olfactory receptor 1115
chr1_-_88657845 1.46 ENSRNOT00000074211
calpain small subunit 1-like
chr10_+_1214731 1.45 ENSRNOT00000080445

chr1_+_63842277 1.42 ENSRNOT00000087957
ENSRNOT00000080820
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3A
chr11_+_34865532 1.42 ENSRNOT00000050342
dual specificity tyrosine phosphorylation regulated kinase 1A
chr15_-_60743064 1.35 ENSRNOT00000013333
A-kinase anchoring protein 11
chr2_+_194557986 1.34 ENSRNOT00000070843
TD and POZ domain-containing protein 2-like
chr15_-_100348760 1.34 ENSRNOT00000085607

chr2_+_192463203 1.30 ENSRNOT00000081253
small proline-rich protein 2H-like
chr10_-_103873246 1.28 ENSRNOT00000039387
Usher syndrome 1G
chr1_+_65292386 1.25 ENSRNOT00000029893

chr12_+_2213705 1.23 ENSRNOT00000031653
mast cell-expressed membrane protein 1
chr8_+_61615650 1.22 ENSRNOT00000007261
snurportin 1
chr14_+_1318157 1.21 ENSRNOT00000061889
vomeronasal 2 receptor, 67

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx19

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 14.2 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208) phospholipase D-activating G-protein coupled receptor signaling pathway(GO:0031583)
3.8 15.2 GO:0060468 prevention of polyspermy(GO:0060468)
2.9 11.5 GO:0030450 regulation of complement activation, classical pathway(GO:0030450)
2.8 11.3 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
2.8 11.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
2.7 10.9 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
2.3 7.0 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
2.0 6.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
1.8 16.3 GO:0070459 prolactin secretion(GO:0070459)
1.7 21.6 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
1.7 33.1 GO:0035404 histone-serine phosphorylation(GO:0035404)
1.6 15.9 GO:0036376 sodium ion export from cell(GO:0036376)
1.5 5.9 GO:0072092 ureteric bud invasion(GO:0072092)
1.4 15.8 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
1.4 5.7 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
1.4 12.5 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
1.4 4.1 GO:2001201 regulation of transforming growth factor-beta secretion(GO:2001201)
1.2 19.1 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
1.2 4.7 GO:1903575 cornified envelope assembly(GO:1903575)
1.1 7.6 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
1.1 6.4 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
1.0 4.2 GO:0071896 protein localization to adherens junction(GO:0071896)
1.0 3.1 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.9 6.6 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.9 17.2 GO:0060081 membrane hyperpolarization(GO:0060081)
0.9 2.6 GO:2000847 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.8 3.3 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.8 2.4 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.7 2.9 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087) mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.7 6.7 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.7 6.7 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.6 2.5 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.6 20.0 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.6 1.2 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.6 4.9 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.6 5.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.6 2.9 GO:0080154 regulation of fertilization(GO:0080154)
0.6 2.8 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.5 1.6 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.5 27.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.5 2.0 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.5 9.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.5 8.8 GO:0043486 histone exchange(GO:0043486)
0.5 3.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.4 9.7 GO:0097503 sialylation(GO:0097503)
0.4 24.1 GO:0034605 cellular response to heat(GO:0034605)
0.4 7.9 GO:0046337 phosphatidylethanolamine metabolic process(GO:0046337)
0.3 13.2 GO:0006040 amino sugar metabolic process(GO:0006040)
0.3 1.9 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.3 1.2 GO:0051030 snRNA transport(GO:0051030)
0.3 2.4 GO:0014042 regulation of mitochondrial fusion(GO:0010635) positive regulation of neuron maturation(GO:0014042)
0.3 0.9 GO:0006649 phospholipid transfer to membrane(GO:0006649)
0.3 7.2 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.3 0.8 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.3 0.8 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.2 7.7 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.2 2.8 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.2 0.7 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.2 10.3 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.2 2.3 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.2 6.7 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.2 3.3 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.2 3.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 1.2 GO:0032674 regulation of interleukin-5 production(GO:0032674)
0.2 2.6 GO:0019236 response to pheromone(GO:0019236)
0.2 0.3 GO:0051081 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.2 2.6 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.3 GO:0050957 equilibrioception(GO:0050957)
0.1 6.6 GO:0033344 cholesterol efflux(GO:0033344)
0.1 5.3 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.1 7.1 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 0.7 GO:0007097 nuclear migration(GO:0007097)
0.1 1.9 GO:0019532 oxalate transport(GO:0019532)
0.1 0.6 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.1 3.8 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.8 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 4.4 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1 1.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 8.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 3.5 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.1 1.5 GO:0001502 cartilage condensation(GO:0001502)
0.1 5.8 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.1 5.6 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 0.9 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.6 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 12.1 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.1 15.1 GO:0016236 macroautophagy(GO:0016236)
0.1 0.5 GO:0046512 sphingosine biosynthetic process(GO:0046512)
0.1 1.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 18.7 GO:0007018 microtubule-based movement(GO:0007018)
0.1 10.6 GO:0008360 regulation of cell shape(GO:0008360)
0.1 3.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 2.3 GO:0018149 peptide cross-linking(GO:0018149)
0.1 6.7 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.1 3.7 GO:0051225 spindle assembly(GO:0051225)
0.1 1.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.4 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.1 3.7 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.1 18.7 GO:0006470 protein dephosphorylation(GO:0006470)
0.1 13.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 6.4 GO:0042476 odontogenesis(GO:0042476)
0.0 5.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.7 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.5 GO:0006415 translational termination(GO:0006415)
0.0 1.4 GO:0031016 pancreas development(GO:0031016)
0.0 7.2 GO:0007409 axonogenesis(GO:0007409)
0.0 4.1 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 3.2 GO:0006814 sodium ion transport(GO:0006814)
0.0 0.4 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 2.4 GO:0030324 lung development(GO:0030324)
0.0 1.1 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.4 19.1 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
2.6 15.9 GO:0044326 dendritic spine neck(GO:0044326)
2.6 15.5 GO:0033269 internode region of axon(GO:0033269)
1.8 33.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
1.7 20.0 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
1.3 6.4 GO:0072534 perineuronal net(GO:0072534)
1.3 7.5 GO:0002081 outer acrosomal membrane(GO:0002081)
1.1 4.5 GO:0034657 GID complex(GO:0034657)
1.1 11.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
1.0 4.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.9 2.8 GO:0000811 GINS complex(GO:0000811)
0.9 17.2 GO:0033268 node of Ranvier(GO:0033268)
0.8 7.6 GO:0031209 SCAR complex(GO:0031209)
0.8 4.1 GO:0071953 elastic fiber(GO:0071953)
0.8 2.4 GO:0070557 PCNA-p21 complex(GO:0070557)
0.8 3.1 GO:0097427 microtubule bundle(GO:0097427)
0.8 15.8 GO:0097449 astrocyte projection(GO:0097449)
0.7 5.9 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.7 18.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.5 19.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.4 2.9 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.4 3.7 GO:0070652 HAUS complex(GO:0070652)
0.3 1.2 GO:0005846 nuclear cap binding complex(GO:0005846)
0.3 1.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 4.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 2.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.2 1.9 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 1.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2 5.8 GO:0046930 pore complex(GO:0046930)
0.2 7.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 7.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 1.8 GO:0017119 Golgi transport complex(GO:0017119)
0.1 9.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 28.2 GO:0043204 perikaryon(GO:0043204)
0.1 6.4 GO:0016235 aggresome(GO:0016235)
0.1 5.4 GO:0031672 A band(GO:0031672)
0.1 9.9 GO:0044291 cell-cell contact zone(GO:0044291)
0.1 1.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 2.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 2.0 GO:0001741 XY body(GO:0001741)
0.1 7.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.5 GO:0043034 costamere(GO:0043034)
0.1 0.6 GO:0033263 CORVET complex(GO:0033263)
0.0 0.9 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 3.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 5.8 GO:0030017 sarcomere(GO:0030017)
0.0 1.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 15.5 GO:0043025 neuronal cell body(GO:0043025)
0.0 10.0 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 2.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 3.2 GO:0005814 centriole(GO:0005814)
0.0 20.0 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 7.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 6.8 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 1.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 7.5 GO:0030141 secretory granule(GO:0030141)
0.0 18.0 GO:0016604 nuclear body(GO:0016604)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 5.6 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 1.6 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 15.8 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
4.7 14.2 GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding(GO:0071886)
3.6 18.0 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
3.2 22.4 GO:1901612 cardiolipin binding(GO:1901612)
2.4 9.7 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
2.4 7.1 GO:0042015 interleukin-20 binding(GO:0042015)
2.3 18.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
2.2 6.6 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
2.2 33.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
1.8 18.0 GO:0045505 dynein intermediate chain binding(GO:0045505)
1.7 6.6 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
1.1 15.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
1.1 3.3 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
1.0 20.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.8 7.4 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.8 5.7 GO:0048495 Roundabout binding(GO:0048495)
0.8 11.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.8 7.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.7 4.1 GO:0070051 fibrinogen binding(GO:0070051)
0.6 3.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.6 7.0 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.6 1.8 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.6 6.0 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.6 11.5 GO:0001618 virus receptor activity(GO:0001618)
0.5 13.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.5 2.5 GO:0089720 caspase binding(GO:0089720)
0.5 2.9 GO:0017040 ceramidase activity(GO:0017040)
0.5 17.2 GO:0030506 ankyrin binding(GO:0030506)
0.4 8.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.4 3.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.4 2.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.4 2.9 GO:0035197 siRNA binding(GO:0035197)
0.4 2.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 1.7 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.3 6.7 GO:0015026 coreceptor activity(GO:0015026)
0.3 19.8 GO:0005080 protein kinase C binding(GO:0005080)
0.3 5.8 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.3 12.4 GO:0030507 spectrin binding(GO:0030507)
0.2 1.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.2 1.2 GO:0000339 RNA cap binding(GO:0000339)
0.2 15.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 8.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 1.6 GO:0004064 arylesterase activity(GO:0004064)
0.2 4.2 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.2 0.6 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700) DNA polymerase processivity factor activity(GO:0030337) dinucleotide insertion or deletion binding(GO:0032139)
0.2 2.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.2 12.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 0.9 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.2 21.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 17.3 GO:0016503 pheromone receptor activity(GO:0016503)
0.2 15.5 GO:0051117 ATPase binding(GO:0051117)
0.2 5.8 GO:0051393 alpha-actinin binding(GO:0051393)
0.2 5.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 7.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 2.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 34.9 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 1.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 5.3 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 1.4 GO:0048156 tau protein binding(GO:0048156)
0.1 3.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 16.0 GO:0051015 actin filament binding(GO:0051015)
0.1 26.4 GO:0008017 microtubule binding(GO:0008017)
0.1 14.5 GO:0005179 hormone activity(GO:0005179)
0.1 5.5 GO:0032947 protein complex scaffold(GO:0032947)
0.1 3.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 8.9 GO:0016410 N-acyltransferase activity(GO:0016410)
0.1 1.0 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 1.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 4.9 GO:0005518 collagen binding(GO:0005518)
0.1 6.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 2.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.8 GO:0030552 cAMP binding(GO:0030552)
0.0 4.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.5 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 1.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 4.4 GO:0042393 histone binding(GO:0042393)
0.0 1.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 3.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 2.3 GO:0008083 growth factor activity(GO:0008083)
0.0 3.4 GO:0008168 methyltransferase activity(GO:0008168)
0.0 5.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 2.3 GO:0005267 potassium channel activity(GO:0005267)
0.0 7.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.9 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.3 7.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.3 6.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.3 1.2 PID IL5 PATHWAY IL5-mediated signaling events
0.3 5.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.3 11.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 11.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 4.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.2 42.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 1.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 12.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.2 2.6 PID IGF1 PATHWAY IGF1 pathway
0.1 7.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 14.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 2.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.7 PID BMP PATHWAY BMP receptor signaling
0.0 2.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 PID CDC42 PATHWAY CDC42 signaling events
0.0 2.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 14.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.9 11.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.8 11.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.8 28.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.7 15.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.6 6.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.5 6.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.4 15.5 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.3 6.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 15.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.3 2.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 7.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 5.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 3.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 6.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.8 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 3.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 3.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.6 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 5.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 4.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 3.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.1 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis