ISMARA results: Tbx19

Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation

Downloads

Results for Tbx19

Z-value: 0.94

Motif logo

Transcription factors associated with Tbx19

Gene Symbol	Gene ID	Gene Info
Tbx19 NCBI RGD Ensembl	ENSRNOG00000002979	T-box 19

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Tbx19	rn6_v1_chr13_-_83425641_83425641	-0.28	3.5e-07	Click!

Activity profile of Tbx19 motif

Sorted Z-values of Tbx19 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr4_-_108717309 Show fit	53.12	ENSRNOT00000085062	AABR07061178.1 NCBI RGD Ensembl Show fit
chr16_+_68633720 Show fit	33.05	ENSRNOT00000081838	LOC100911229 NCBI RGD Ensembl Show fit	sperm motility kinase-like
chr2_-_21437193 Show fit	21.76	ENSRNOT00000084002	Ckmt2 NCBI RGD Ensembl Show fit	creatine kinase, mitochondrial 2
chr2_-_19808937 Show fit	20.05	ENSRNOT00000044237	Atp6ap1l NCBI RGD Ensembl Show fit	ATPase H+ transporting accessory protein 1 like
chr1_+_105349069 Show fit	19.82	ENSRNOT00000056030	Nell1 NCBI RGD Ensembl Show fit	neural EGFL like 1
chr9_-_65879521 Show fit	19.57	ENSRNOT00000017517	Als2cr11 NCBI RGD Ensembl Show fit	amyotrophic lateral sclerosis 2 chromosome region, candidate 11
chr7_+_27620458 Show fit	19.29	ENSRNOT00000059532	RGD1560034 NCBI RGD Ensembl Show fit	similar to FLJ25323 protein
chr19_-_56633633 Show fit	19.10	ENSRNOT00000023911	Ccsap NCBI RGD Ensembl Show fit	centriole, cilia and spindle-associated protein
chr6_+_48452369 Show fit	18.22	ENSRNOT00000044310	Myt1l NCBI RGD Ensembl Show fit	myelin transcription factor 1-like
chr19_+_49016891 Show fit	18.01	ENSRNOT00000016713	Dynlrb2 NCBI RGD Ensembl Show fit	dynein light chain roadblock-type 2

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx19

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	33.1	GO:0035404	histone-serine phosphorylation(GO:0035404)
0.5	27.9	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.4	24.1	GO:0034605	cellular response to heat(GO:0034605)
1.7	21.6	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.6	20.0	GO:0015991	ATP hydrolysis coupled proton transport(GO:0015991)
1.2	19.1	GO:1901673	regulation of mitotic spindle assembly(GO:1901673)
0.1	18.7	GO:0007018	microtubule-based movement(GO:0007018)
0.1	18.7	GO:0006470	protein dephosphorylation(GO:0006470)
0.9	17.2	GO:0060081	membrane hyperpolarization(GO:0060081)
1.8	16.3	GO:0070459	prolactin secretion(GO:0070459)

Showing 1 to 10 of 112 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	33.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	28.2	GO:0043204	perikaryon(GO:0043204)
1.7	20.0	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	20.0	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.5	19.3	GO:0032391	photoreceptor connecting cilium(GO:0032391)
6.4	19.1	GO:0061673	mitotic spindle astral microtubule(GO:0061673)
0.7	18.0	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	18.0	GO:0016604	nuclear body(GO:0016604)
0.9	17.2	GO:0033268	node of Ranvier(GO:0033268)
2.6	15.9	GO:0044326	dendritic spine neck(GO:0044326)

Showing 1 to 10 of 64 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	34.9	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
2.2	33.1	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.1	26.4	GO:0008017	microtubule binding(GO:0008017)
3.2	22.4	GO:1901612	cardiolipin binding(GO:1901612)
0.2	21.8	GO:0004222	metalloendopeptidase activity(GO:0004222)
1.0	20.0	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.3	19.8	GO:0005080	protein kinase C binding(GO:0005080)
2.3	18.2	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
3.6	18.0	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
1.8	18.0	GO:0045505	dynein intermediate chain binding(GO:0045505)

Showing 1 to 10 of 86 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	42.1	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	14.9	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.2	12.7	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.3	11.3	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.2	11.3	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.1	7.6	PID RAC1 PATHWAY	RAC1 signaling pathway
0.3	7.2	PID NECTIN PATHWAY	Nectin adhesion pathway
0.3	6.6	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.3	5.9	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.2	4.4	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway

Showing 1 to 10 of 20 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	28.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.3	15.9	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.7	15.8	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.4	15.5	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
1.0	14.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.8	11.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.9	11.3	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.2	7.0	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	6.7	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.6	6.6	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis

Showing 1 to 10 of 32 entries

Results for Tbx19

Z-value: 0.94

Motif logo

Transcription factors associated with Tbx19

Activity-expression correlation:

Activity profile of Tbx19 motif

Sorted Z-values of Tbx19 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx19

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: