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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Tbx15

Z-value: 0.80

Motif logo

Transcription factors associated with Tbx15

Gene Symbol Gene ID Gene Info
ENSRNOG00000019565 T-box 15

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tbx15rn6_v1_chr2_+_201289357_2012893570.026.6e-01Click!

Activity profile of Tbx15 motif

Sorted Z-values of Tbx15 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_53609214 70.85 ENSRNOT00000077443
solute carrier family 27 member 6
chr4_-_148845267 28.44 ENSRNOT00000037397
transmembrane protein 72
chr3_+_61620192 21.01 ENSRNOT00000065426
homeo box D9
chr2_-_23289266 19.57 ENSRNOT00000061708
betaine-homocysteine S-methyltransferase 2
chr1_+_7252349 17.31 ENSRNOT00000030329
PLAG1 like zinc finger 1
chr2_+_60920257 13.46 ENSRNOT00000025170
C1q and tumor necrosis factor related protein 3
chr11_-_81717521 12.45 ENSRNOT00000058422
alpha-2-HS-glycoprotein
chr6_-_127653124 11.32 ENSRNOT00000047324
serpin family A member 11
chr8_-_78233430 10.79 ENSRNOT00000083220
cingulin-like 1
chrX_-_142248369 10.77 ENSRNOT00000091330
fibroblast growth factor 13
chr13_-_25262469 10.73 ENSRNOT00000019921
ring finger protein 152
chr1_+_224824799 10.67 ENSRNOT00000024757
solute carrier family 22 member 6
chr16_+_46731403 10.67 ENSRNOT00000017624
teneurin transmembrane protein 3
chr14_+_12218553 10.63 ENSRNOT00000003237
protein kinase, cGMP-dependent, type II
chr1_+_48273611 10.51 ENSRNOT00000022254
ENSRNOT00000022068
solute carrier family 22 member 1
chr1_+_238222521 9.49 ENSRNOT00000024000
aldehyde dehydrogenase 1 family, member A1
chrX_-_139464798 9.29 ENSRNOT00000003282
glypican 4
chr18_+_69841053 9.16 ENSRNOT00000071545
ENSRNOT00000030613
ENSRNOT00000075543
maestro
chr7_-_29152442 8.76 ENSRNOT00000079774
myosin binding protein C, slow type
chr13_+_75105615 8.67 ENSRNOT00000076653
tumor protein p53 inducible protein 3
chr20_-_45126062 8.42 ENSRNOT00000000720
similar to KIAA1919 protein
chr2_+_22909569 8.28 ENSRNOT00000073871
homer scaffolding protein 1
chr12_-_46920952 8.09 ENSRNOT00000001532
musashi RNA-binding protein 1
chr12_-_41627741 8.07 ENSRNOT00000001875
serine dehydratase
chr4_-_82194927 7.94 ENSRNOT00000072302
homeobox protein Hox-A9
chr16_-_62373253 7.84 ENSRNOT00000034325
testis expressed 15, meiosis and synapsis associated
chr1_+_170471238 7.73 ENSRNOT00000076961
ENSRNOT00000075597
ENSRNOT00000076631
ENSRNOT00000076783
translocase of inner mitochondrial membrane 10B
dynein heavy chain domain 1
chr8_+_117068582 7.64 ENSRNOT00000073559
aminomethyltransferase
chr5_+_33784715 7.58 ENSRNOT00000035685
solute carrier family 7 member 13
chr10_+_86657285 7.45 ENSRNOT00000087346
thyroid hormone receptor alpha
chr12_+_19196611 6.95 ENSRNOT00000001801
alpha-2-glycoprotein 1, zinc-binding
chr1_+_80777014 6.93 ENSRNOT00000079758
predicted gene, 19345
chr16_+_18690649 6.91 ENSRNOT00000015190
methionine adenosyltransferase 1A
chr1_+_30681681 6.65 ENSRNOT00000015395
R-spondin 3
chr17_-_10640548 6.53 ENSRNOT00000064274
SUMO-interacting motifs containing 1
chr17_-_8607494 6.48 ENSRNOT00000016138
solute carrier family 25, member 48
chr13_+_49074644 6.21 ENSRNOT00000000041
kelch domain containing 8A
chr12_-_23661009 5.99 ENSRNOT00000059451
uroplakin 3B-like
chr15_-_33527031 5.88 ENSRNOT00000019979
homeobox and leucine zipper encoding
chr4_+_58053041 5.87 ENSRNOT00000072698
mesoderm specific transcript
chr7_-_62972084 5.73 ENSRNOT00000064251
methionine sulfoxide reductase B3
chr9_+_100281339 5.70 ENSRNOT00000029127
alanine-glyoxylate aminotransferase
chr4_+_68849033 5.70 ENSRNOT00000016912
maltase-glucoamylase
chr17_-_10622063 5.57 ENSRNOT00000022980
SUMO-interacting motifs containing 1
chr11_+_27208564 5.51 ENSRNOT00000002158
MAP3K7 C-terminal like
chr5_-_135561914 5.50 ENSRNOT00000023178
methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
chr2_-_210738378 5.42 ENSRNOT00000025746
glutathione S-transferase, mu 6
chr2_-_53185926 5.41 ENSRNOT00000081558
growth hormone receptor
chrX_+_15295473 5.37 ENSRNOT00000009295
histone deacetylase 6
chr9_-_63637677 5.33 ENSRNOT00000049259
SATB homeobox 2
chr5_-_12563429 5.32 ENSRNOT00000059625
suppression of tumorigenicity 18
chr8_-_86286991 5.32 ENSRNOT00000046322
similar to RIKEN cDNA 2900055D03
chr2_-_187435323 5.31 ENSRNOT00000050476
tetratricopeptide repeat domain 24
chr11_-_32508420 5.28 ENSRNOT00000002717
potassium voltage-gated channel subfamily E regulatory subunit 1
chrX_-_111102464 5.23 ENSRNOT00000084176
ripply transcriptional repressor 1
chr5_-_159962218 4.99 ENSRNOT00000050729
chloride voltage-gated channel Kb
chr11_+_74057361 4.85 ENSRNOT00000048746
carboxypeptidase N subunit 2
chr7_+_129595192 4.82 ENSRNOT00000071151
zinc finger, DHHC-type containing 25
chr13_-_50509916 4.79 ENSRNOT00000076747
renin
chr4_+_71675383 4.76 ENSRNOT00000051265
chloride voltage-gated channel 1
chr4_-_70974006 4.69 ENSRNOT00000020975
transient receptor potential cation channel, subfamily V, member 5
chr4_-_70973842 4.69 ENSRNOT00000051687
transient receptor potential cation channel, subfamily V, member 5
chr19_-_25288335 4.30 ENSRNOT00000050214
nanos C2HC-type zinc finger 3
chr2_+_207262934 4.28 ENSRNOT00000016833
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr5_-_173680290 4.24 ENSRNOT00000027564
sterile alpha motif domain containing 11
chr8_+_91464229 4.17 ENSRNOT00000013249
branched chain keto acid dehydrogenase E1 subunit beta
chr1_-_81946714 4.11 ENSRNOT00000027578
glutamate ionotropic receptor kainate type subunit 5
chr4_-_15859132 4.06 ENSRNOT00000082161
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr2_-_210749991 4.05 ENSRNOT00000051261
ENSRNOT00000052403
glutathione S-transferase, mu 6-like
chr10_+_85608544 4.01 ENSRNOT00000092122
MLLT6, PHD finger domain containing
chr10_-_56511583 4.00 ENSRNOT00000021402
similar to RIKEN cDNA 2810408A11
chr11_-_65845418 3.97 ENSRNOT00000091057
follistatin-like 1
chr1_-_215373234 3.90 ENSRNOT00000034299

chr19_+_25262076 3.89 ENSRNOT00000030658
hypothetical LOC304654
chr12_+_9464026 3.89 ENSRNOT00000048188
caudal type homeo box 2
chr16_-_70705128 3.86 ENSRNOT00000071258
ring finger protein 170
chr10_+_36554416 3.85 ENSRNOT00000049730
olfactory receptor 1411
chr10_-_18574909 3.80 ENSRNOT00000083090
potassium voltage-gated channel interacting protein 1
chr2_+_127845034 3.78 ENSRNOT00000044804
La ribonucleoprotein domain family, member 1B
chr1_-_215350161 3.77 ENSRNOT00000081144
ENSRNOT00000064050

chr4_-_157439507 3.75 ENSRNOT00000081802
parathymosin
chr1_-_102780381 3.72 ENSRNOT00000080132
serum amyloid A4
chr4_+_147037179 3.66 ENSRNOT00000011292
synapsin II
chr1_+_88324339 3.66 ENSRNOT00000072762
zinc finger protein 420-like
chrX_+_135348436 3.62 ENSRNOT00000008868
RAB33A, member RAS oncogene family
chr14_-_80973456 3.62 ENSRNOT00000013257
HGF activator
chr1_+_87903783 3.61 ENSRNOT00000074299
zinc finger protein 84
chr10_-_74119009 3.60 ENSRNOT00000085712
ENSRNOT00000006926
DEAH-box helicase 40
chr5_+_127925726 3.52 ENSRNOT00000014401
cytochrome c oxidase assembly factor 7
chr3_-_113423149 3.51 ENSRNOT00000021008
serine incorporator 4
chr4_+_82370997 3.50 ENSRNOT00000072934
even-skipped homeobox 1
chr20_-_4366957 3.48 ENSRNOT00000088244
ring finger protein 5
chr6_-_25616995 3.45 ENSRNOT00000077894
FOS like 2, AP-1 transcription factor subunit
chr10_+_65772443 3.45 ENSRNOT00000013296
SEBOX homeobox
chr15_+_33822730 3.42 ENSRNOT00000067607
similar to dehydrogenase/reductase member 2
chr1_-_170471076 3.39 ENSRNOT00000025159
ADP-ribosylation factor interacting protein 2
chr5_-_126096068 3.36 ENSRNOT00000036793

chr8_+_131845696 3.35 ENSRNOT00000005440
T cell activation inhibitor, mitochondrial
chr7_+_38945836 3.34 ENSRNOT00000006455
coiled-coil glutamate-rich protein 1
chr11_-_24294179 3.23 ENSRNOT00000002116
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr4_-_117126822 3.16 ENSRNOT00000086720
RAB11 family interacting protein 5
chr10_+_84182118 3.12 ENSRNOT00000011027
homeo box B3
chr19_+_25029037 3.10 ENSRNOT00000045699
adhesion G protein-coupled receptor L1
chr1_+_172822544 3.09 ENSRNOT00000090018

chr3_+_9643047 3.06 ENSRNOT00000035805
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr19_-_53497006 3.03 ENSRNOT00000074005
F-box protein 31
chr10_-_18574710 3.02 ENSRNOT00000079031
potassium voltage-gated channel interacting protein 1
chr19_+_24496569 3.00 ENSRNOT00000004982
MGAT4 family, member D
chrX_-_15428518 3.00 ENSRNOT00000075774
proSAAS
chr14_+_42714315 2.97 ENSRNOT00000084095
ENSRNOT00000091449
paired-like homeobox 2b
chr5_+_135562034 2.95 ENSRNOT00000056967
coiled-coil domain containing 163
chr16_-_48437223 2.94 ENSRNOT00000013005
ENSRNOT00000059401
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr1_+_72810545 2.92 ENSRNOT00000092117
protein tyrosine phosphatase, receptor type, H
chr13_+_42220251 2.92 ENSRNOT00000078185

chr16_+_20672374 2.90 ENSRNOT00000063780
similar to RIKEN cDNA 2810428I15
chr12_+_49419582 2.89 ENSRNOT00000082998
similar to hypothetical protein A530094D01
chr12_+_40466495 2.87 ENSRNOT00000001816
aldehyde dehydrogenase 2 family (mitochondrial)
chr13_+_49092306 2.86 ENSRNOT00000000039
NUAK family kinase 2
chr10_+_13196946 2.84 ENSRNOT00000071525
protease, serine, 32
chr8_+_20728817 2.83 ENSRNOT00000050101
olfactory receptor 1179
chr9_-_11114843 2.78 ENSRNOT00000072031
Epstein-Barr virus induced 3
chr1_+_102258124 2.74 ENSRNOT00000068434
otogelin
chrX_-_15327684 2.74 ENSRNOT00000009794
proprotein convertase subtilisin/kexin type 1 inhibitor
chr14_-_3462629 2.73 ENSRNOT00000061538
bromodomain testis associated
chr3_-_177095597 2.71 ENSRNOT00000029386
sterile alpha motif domain containing 10
chr5_+_58393603 2.70 ENSRNOT00000080082
DnaJ heat shock protein family (Hsp40) member B5
chr4_+_71795768 2.69 ENSRNOT00000031921
taste receptor, type 2, member 135
chr10_-_61772250 2.66 ENSRNOT00000092338
ENSRNOT00000085394
ENSRNOT00000046110
serine racemase
chr3_-_4394428 2.64 ENSRNOT00000044775
ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
chr1_+_79982639 2.62 ENSRNOT00000071916
dystrophia myotonica, WD repeat containing
chr1_-_206394346 2.62 ENSRNOT00000038122
hypothetical LOC100302465
chr1_-_87937516 2.60 ENSRNOT00000087522
eukaryotic translation initiation factor 3, subunit K
chr16_-_81834945 2.59 ENSRNOT00000037806
coagulation factor VII
chr13_-_90832138 2.58 ENSRNOT00000010930
immunoglobulin superfamily, member 9
chr5_-_138697641 2.58 ENSRNOT00000012062
guanylate cyclase activator 2B
chr4_+_114835064 2.56 ENSRNOT00000031964
rhotekin
chr5_+_63781801 2.55 ENSRNOT00000008302
nuclear receptor subfamily 4, group A, member 3
chr18_-_70924708 2.53 ENSRNOT00000025257
lipase G, endothelial type
chr1_+_220243473 2.52 ENSRNOT00000084650
ENSRNOT00000027091
mitochondrial ribosomal protein L11
chr1_-_81163689 2.50 ENSRNOT00000088746
zinc finger protein 45-like
chr3_-_5402666 2.47 ENSRNOT00000061276
histo-blood group ABO system transferase 2
chr3_-_176706896 2.45 ENSRNOT00000017337
protein tyrosine kinase 6
chr10_+_44804631 2.44 ENSRNOT00000040720
olfactory receptor 1460
chr18_+_61261418 2.44 ENSRNOT00000064250
zinc finger protein 532
chr5_+_157327657 2.43 ENSRNOT00000022847
phospholipase A2, group IIE
chr1_+_88542035 2.40 ENSRNOT00000032973
zinc finger protein 420
chr6_+_101532518 2.37 ENSRNOT00000075054
gephyrin
chr4_+_9981958 2.35 ENSRNOT00000015322
N-acyl phosphatidylethanolamine phospholipase D
chr8_+_39687269 2.35 ENSRNOT00000012060
transmembrane protein 218
chr1_+_172051215 2.34 ENSRNOT00000048370
olfactory receptor 235
chr14_+_3882398 2.34 ENSRNOT00000033794
HFM1, ATP-dependent DNA helicase homolog
chr4_+_79846521 2.32 ENSRNOT00000029332
membrane palmitoylated protein 6
chr7_+_54859104 2.30 ENSRNOT00000087341
calcyphosine 2
chr1_+_85485289 2.27 ENSRNOT00000026182
delta like canonical Notch ligand 3
chr10_+_109966904 2.23 ENSRNOT00000085821
G protein pathway suppressor 1
chr1_+_248402980 2.21 ENSRNOT00000043517
coiled-coil-helix-coiled-coil-helix domain containing 4
chr19_-_25345790 2.21 ENSRNOT00000010050
zinc finger, SWIM-type containing 4
chr6_-_60124274 2.18 ENSRNOT00000059823
leucine-rich single-pass membrane protein 1
chr1_-_81559685 2.17 ENSRNOT00000075282
CD177 antigen-like
chr8_-_55171718 2.16 ENSRNOT00000080736
hypothetical protein LOC689959
chr4_+_174181644 2.14 ENSRNOT00000011555
capping actin protein of muscle Z-line alpha subunit 3
chr12_+_8032809 2.13 ENSRNOT00000082850
solute carrier family 7 member 1
chr4_+_1601652 2.13 ENSRNOT00000072284
olfactory receptor 8B3-like
chr7_-_107774397 2.13 ENSRNOT00000093322
N-myc downstream regulated 1
chr18_+_63016577 2.11 ENSRNOT00000025147
inositol monophosphatase 2
chr13_+_71656651 2.11 ENSRNOT00000050365
zinc finger protein 648
chr1_-_81152384 2.10 ENSRNOT00000026263
ENSRNOT00000077305
zinc finger protein 94
chr5_-_152458023 2.08 ENSRNOT00000031225
connector enhancer of kinase suppressor of Ras 1
chr8_+_42409187 2.08 ENSRNOT00000072605
olfactory receptor 1256
chr10_-_102227554 2.08 ENSRNOT00000078035

chr1_-_264975132 2.06 ENSRNOT00000021748
ladybird homeobox 1
chr8_-_82533689 2.04 ENSRNOT00000014124
tropomodulin 2
chr6_+_101865917 2.04 ENSRNOT00000029888
family with sequence similarity 71, member D
chr6_+_28323647 2.02 ENSRNOT00000089093
DNA methyltransferase 3 alpha
chr6_-_3444519 2.00 ENSRNOT00000010366
mitogen-activated protein kinase kinase kinase kinase 3
chrX_+_110789269 1.98 ENSRNOT00000086014
ring finger protein 128, E3 ubiquitin protein ligase
chr1_+_148240504 1.98 ENSRNOT00000085373
Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chr9_-_82336806 1.96 ENSRNOT00000024667
solute carrier family 23, member 3
chr6_+_107531528 1.94 ENSRNOT00000077555
acyl-CoA thioesterase 3
chr15_-_49467174 1.93 ENSRNOT00000019209
ADAM metallopeptidase domain 7
chr4_+_123586231 1.93 ENSRNOT00000049657
ENSRNOT00000013232
glutamate receptor interacting protein 2
chr15_+_120372 1.92 ENSRNOT00000007828
discs large MAGUK scaffold protein 5
chr1_+_276309927 1.91 ENSRNOT00000067460
ENSRNOT00000066236
vesicle transport through interaction with t-SNAREs 1A
chr17_-_10559627 1.91 ENSRNOT00000023515
HIG1 hypoxia inducible domain family, member 2A
chr3_+_161433410 1.90 ENSRNOT00000024657
solute carrier family 12 member 5
chr1_+_79989019 1.89 ENSRNOT00000020428
dystrophia myotonica-protein kinase
chr10_-_87232723 1.87 ENSRNOT00000015150
keratin 25
chr20_-_4280795 1.86 ENSRNOT00000081431
similar to butyrophilin-like 7
chr12_-_50213400 1.85 ENSRNOT00000048541
trichohyalin-like
chr12_+_52359310 1.85 ENSRNOT00000071857
ENSRNOT00000065893
fibrosin-like 1
chr7_-_3074359 1.85 ENSRNOT00000019738
IKAROS family zinc finger 4
chr8_+_36625733 1.84 ENSRNOT00000016248
cell adhesion associated, oncogene regulated
chr5_-_66322567 1.82 ENSRNOT00000032726
cylicin 2
chr9_+_112360419 1.82 ENSRNOT00000086682
mannosidase, alpha, class 2A, member 1
chr7_+_54859326 1.81 ENSRNOT00000039141
calcyphosine 2
chr5_-_168004724 1.81 ENSRNOT00000024711
Parkinsonism associated deglycase
chr16_-_20640720 1.80 ENSRNOT00000083254

chr4_+_145399913 1.79 ENSRNOT00000012177
jagunal homolog 1
chr5_-_150704117 1.78 ENSRNOT00000067455
sestrin 2
chr13_+_99005142 1.78 ENSRNOT00000004293
acyl-CoA binding domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx15

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.6 GO:2001226 negative regulation of chloride transport(GO:2001226)
3.0 3.0 GO:0048880 sensory system development(GO:0048880)
2.5 7.4 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
2.4 19.6 GO:0071267 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
2.1 16.6 GO:0070163 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
2.0 8.1 GO:0006565 L-serine catabolic process(GO:0006565)
1.9 5.7 GO:0030091 protein repair(GO:0030091)
1.9 7.6 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.9 5.7 GO:0046439 cysteine catabolic process(GO:0009093) glycine biosynthetic process, by transamination of glyoxylate(GO:0019265) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439) oxalic acid secretion(GO:0046724)
1.8 10.7 GO:0031427 response to methotrexate(GO:0031427)
1.8 21.0 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
1.5 10.8 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
1.4 4.3 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
1.4 6.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
1.3 6.5 GO:0000066 mitochondrial ornithine transport(GO:0000066)
1.2 9.5 GO:0042904 optic cup morphogenesis involved in camera-type eye development(GO:0002072) 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.2 10.5 GO:0015697 quaternary ammonium group transport(GO:0015697)
1.0 3.1 GO:0006480 N-terminal protein amino acid methylation(GO:0006480) peptidyl-glycine modification(GO:0018201)
1.0 10.7 GO:0097264 self proteolysis(GO:0097264)
1.0 6.8 GO:0006621 protein retention in ER lumen(GO:0006621)
1.0 4.8 GO:0002018 angiotensin maturation(GO:0002003) renin-angiotensin regulation of aldosterone production(GO:0002018)
0.9 9.4 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.9 2.7 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.9 2.7 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.9 8.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.9 2.6 GO:1905225 response to 2,3,7,8-tetrachlorodibenzodioxine(GO:1904612) response to thyrotropin-releasing hormone(GO:1905225)
0.8 2.5 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.8 12.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.8 5.5 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.8 3.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.8 9.3 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.7 2.2 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.7 5.0 GO:0030321 transepithelial chloride transport(GO:0030321)
0.6 1.9 GO:0032789 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.6 3.2 GO:0060005 vestibular reflex(GO:0060005)
0.6 68.5 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.6 1.8 GO:0050787 enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) TRAIL receptor biosynthetic process(GO:0045557) regulation of TRAIL receptor biosynthetic process(GO:0045560) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.6 5.4 GO:0072338 allantoin metabolic process(GO:0000255) isoleucine metabolic process(GO:0006549) creatine metabolic process(GO:0006600) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.6 2.4 GO:1903999 negative regulation of eating behavior(GO:1903999)
0.6 1.7 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.6 2.3 GO:0007386 compartment pattern specification(GO:0007386)
0.5 2.6 GO:0051691 cellular oligosaccharide metabolic process(GO:0051691)
0.5 12.4 GO:0046852 negative regulation of bone mineralization(GO:0030502) positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.5 1.6 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.5 8.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.5 3.6 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.5 1.5 GO:0045054 constitutive secretory pathway(GO:0045054)
0.5 3.4 GO:0001661 conditioned taste aversion(GO:0001661)
0.5 1.5 GO:2000040 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.5 5.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.5 1.9 GO:0071896 protein localization to adherens junction(GO:0071896)
0.5 6.6 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.5 2.4 GO:0007529 establishment of synaptic specificity at neuromuscular junction(GO:0007529) gamma-aminobutyric acid receptor clustering(GO:0097112)
0.5 5.7 GO:0015825 L-serine transport(GO:0015825)
0.4 1.3 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.4 3.9 GO:0014807 regulation of somitogenesis(GO:0014807)
0.4 1.7 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.4 1.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.4 1.9 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.4 4.8 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.4 1.1 GO:0030920 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.4 9.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.3 4.2 GO:0009081 branched-chain amino acid metabolic process(GO:0009081)
0.3 2.0 GO:0044027 hypermethylation of CpG island(GO:0044027) C-5 methylation of cytosine(GO:0090116)
0.3 4.0 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.3 2.1 GO:1903826 arginine transmembrane transport(GO:1903826) basic amino acid transmembrane transport(GO:1990822)
0.3 3.3 GO:0006013 mannose metabolic process(GO:0006013)
0.3 2.9 GO:0019695 choline metabolic process(GO:0019695)
0.3 2.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.3 7.8 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569) male genitalia development(GO:0030539)
0.3 2.1 GO:0006021 inositol biosynthetic process(GO:0006021)
0.3 1.8 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.3 2.9 GO:0006068 ethanol catabolic process(GO:0006068)
0.3 0.5 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.3 3.0 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.3 0.5 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.2 2.7 GO:0019321 pentose metabolic process(GO:0019321)
0.2 1.2 GO:0044704 mating plug formation(GO:0042628) single-organism reproductive behavior(GO:0044704) post-mating behavior(GO:0045297)
0.2 1.9 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.2 1.7 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.2 1.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 2.6 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.2 0.9 GO:0032687 negative regulation of interferon-alpha production(GO:0032687) regulation of toll-like receptor 9 signaling pathway(GO:0034163)
0.2 0.7 GO:2000853 negative regulation of corticosterone secretion(GO:2000853)
0.2 0.9 GO:0045226 hyaluranon cable assembly(GO:0036118) extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.2 2.2 GO:0000338 protein deneddylation(GO:0000338)
0.2 16.7 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.2 0.6 GO:0035262 gonad morphogenesis(GO:0035262)
0.2 1.0 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.2 2.7 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.2 3.4 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.2 2.1 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.2 1.9 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 8.7 GO:0006739 NADP metabolic process(GO:0006739)
0.2 2.1 GO:0048664 neuron fate determination(GO:0048664)
0.2 2.6 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.2 1.8 GO:0030223 neutrophil differentiation(GO:0030223)
0.2 0.5 GO:0051697 protein delipidation(GO:0051697)
0.1 2.1 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 2.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.4 GO:2000541 positive regulation of synaptic growth at neuromuscular junction(GO:0045887) regulation of protein geranylgeranylation(GO:2000539) positive regulation of protein geranylgeranylation(GO:2000541)
0.1 2.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 2.6 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 2.6 GO:0031572 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.1 3.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.9 GO:0071318 cellular response to ATP(GO:0071318)
0.1 0.4 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 0.8 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 2.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 3.5 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 1.1 GO:0051382 kinetochore assembly(GO:0051382)
0.1 1.7 GO:0045760 positive regulation of action potential(GO:0045760)
0.1 1.9 GO:0045109 intermediate filament organization(GO:0045109)
0.1 2.3 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.1 4.0 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 0.7 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.6 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.1 0.1 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.1 2.9 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 2.2 GO:0003016 respiratory system process(GO:0003016)
0.1 5.6 GO:0048477 oogenesis(GO:0048477)
0.1 0.6 GO:0036005 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.1 0.7 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.5 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.1 0.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 5.2 GO:0060349 bone morphogenesis(GO:0060349)
0.1 1.5 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.3 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.0 0.4 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.2 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.4 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 1.0 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 2.7 GO:0006986 response to unfolded protein(GO:0006986)
0.0 2.6 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of autophagosome maturation(GO:1901097)
0.0 7.1 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 1.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.8 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 1.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.3 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 3.2 GO:0007286 spermatid development(GO:0007286)
0.0 1.9 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 1.2 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 22.4 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.2 GO:0031424 keratinization(GO:0031424)
0.0 2.1 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 2.6 GO:0007018 microtubule-based movement(GO:0007018)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
1.1 5.4 GO:0070195 growth hormone receptor complex(GO:0070195)
0.8 4.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.7 8.8 GO:0005859 muscle myosin complex(GO:0005859)
0.7 4.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.4 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.3 4.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.3 2.6 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282) eukaryotic 48S preinitiation complex(GO:0033290)
0.3 0.9 GO:0036117 hyaluranon cable(GO:0036117)
0.3 4.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 5.7 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 3.5 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.2 3.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 1.8 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 2.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.2 1.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 10.8 GO:0016459 myosin complex(GO:0016459)
0.2 1.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 7.9 GO:0043034 costamere(GO:0043034)
0.2 5.0 GO:0060077 inhibitory synapse(GO:0060077)
0.2 8.1 GO:0005844 polysome(GO:0005844)
0.2 1.6 GO:0030891 VCB complex(GO:0030891)
0.1 15.6 GO:0072562 blood microparticle(GO:0072562)
0.1 1.5 GO:0005796 Golgi lumen(GO:0005796)
0.1 3.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 9.4 GO:0005581 collagen trimer(GO:0005581)
0.1 3.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 7.0 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.7 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.5 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 12.2 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.1 GO:0044615 nuclear pore central transport channel(GO:0044613) nuclear pore nuclear basket(GO:0044615)
0.1 0.7 GO:0097255 R2TP complex(GO:0097255)
0.1 6.1 GO:0014704 intercalated disc(GO:0014704)
0.1 2.0 GO:0001741 XY body(GO:0001741)
0.1 10.7 GO:0005901 caveola(GO:0005901)
0.1 4.5 GO:0031201 SNARE complex(GO:0031201)
0.1 1.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.7 GO:0001520 outer dense fiber(GO:0001520)
0.1 4.5 GO:0005801 cis-Golgi network(GO:0005801)
0.1 9.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 6.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.6 GO:0031415 NatA complex(GO:0031415)
0.1 1.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 5.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.7 GO:0032426 stereocilium tip(GO:0032426)
0.1 4.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.9 GO:0032590 dendrite membrane(GO:0032590)
0.1 7.1 GO:0016363 nuclear matrix(GO:0016363)
0.1 2.2 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.8 GO:0060091 kinocilium(GO:0060091)
0.1 0.3 GO:0030312 external encapsulating structure(GO:0030312)
0.1 4.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 2.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 2.5 GO:1904115 axon cytoplasm(GO:1904115)
0.0 11.6 GO:0031301 integral component of organelle membrane(GO:0031301)
0.0 3.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 2.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 3.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 2.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 2.9 GO:0005902 microvillus(GO:0005902)
0.0 2.9 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0033647 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 1.5 GO:0045095 keratin filament(GO:0045095)
0.0 13.1 GO:0016604 nuclear body(GO:0016604)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 3.4 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 29.5 GO:0005739 mitochondrion(GO:0005739)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 2.2 GO:0030017 sarcomere(GO:0030017)
0.0 1.2 GO:0005681 spliceosomal complex(GO:0005681)
0.0 8.0 GO:0005730 nucleolus(GO:0005730)
0.0 0.5 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0031594 neuromuscular junction(GO:0031594)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 70.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
3.6 10.7 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
3.5 10.5 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
3.2 9.5 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
3.1 12.3 GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294)
2.4 19.6 GO:0008172 S-methyltransferase activity(GO:0008172)
2.3 6.9 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
2.1 10.6 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
1.7 8.3 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
1.5 12.1 GO:0032184 SUMO polymer binding(GO:0032184)
1.4 8.7 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
1.4 5.7 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
1.4 5.7 GO:0016160 amylase activity(GO:0016160)
1.4 4.1 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
1.4 5.4 GO:0004903 growth hormone receptor activity(GO:0004903)
1.3 10.7 GO:0031404 chloride ion binding(GO:0031404)
1.1 5.7 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
1.0 3.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.8 4.2 GO:0042731 PH domain binding(GO:0042731)
0.8 6.5 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.8 5.3 GO:0031433 telethonin binding(GO:0031433)
0.7 2.9 GO:0070404 NADH binding(GO:0070404)
0.7 8.8 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.6 7.4 GO:0070324 thyroid hormone binding(GO:0070324)
0.6 1.8 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.6 2.4 GO:0008940 nitrate reductase activity(GO:0008940)
0.5 2.7 GO:0046923 ER retention sequence binding(GO:0046923)
0.5 9.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.5 2.5 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.5 5.7 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.5 4.2 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.5 5.5 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.4 3.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.4 1.3 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.4 2.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.4 10.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.4 2.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.4 1.7 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.4 2.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.4 2.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.4 8.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.4 2.6 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.4 2.9 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.4 1.1 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.3 1.0 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.3 3.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.3 2.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 0.6 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.3 2.1 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832)
0.3 1.8 GO:0070728 leucine binding(GO:0070728)
0.2 9.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 10.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.2 4.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 3.0 GO:0033038 bitter taste receptor activity(GO:0033038)
0.2 5.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 1.8 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 3.6 GO:0015643 toxic substance binding(GO:0015643)
0.2 0.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 0.5 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.2 3.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.2 0.6 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 6.6 GO:0005109 frizzled binding(GO:0005109)
0.2 1.9 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 3.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 4.9 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 2.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 2.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 2.6 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 1.6 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.9 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1 1.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 16.3 GO:0003774 motor activity(GO:0003774)
0.1 2.0 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.7 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 3.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.5 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.1 2.3 GO:0005112 Notch binding(GO:0005112)
0.1 3.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 0.9 GO:0046790 virion binding(GO:0046790)
0.1 3.1 GO:0030332 cyclin binding(GO:0030332)
0.1 1.9 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 2.2 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 1.9 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 2.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 5.9 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.7 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 7.0 GO:0015297 antiporter activity(GO:0015297)
0.1 4.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 2.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 2.0 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.1 7.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 12.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 1.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 3.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 2.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 3.4 GO:0008013 beta-catenin binding(GO:0008013)
0.0 8.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 3.5 GO:0051082 unfolded protein binding(GO:0051082)
0.0 2.7 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 3.3 GO:0003823 antigen binding(GO:0003823)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 3.3 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 5.6 GO:0008168 methyltransferase activity(GO:0008168)
0.0 2.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 2.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.7 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 3.7 GO:0016758 transferase activity, transferring hexosyl groups(GO:0016758)
0.0 22.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 4.2 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 5.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.2 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.5 GO:0005262 calcium channel activity(GO:0005262)
0.0 5.4 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.4 GO:0015485 cholesterol binding(GO:0015485)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 12.4 PID BMP PATHWAY BMP receptor signaling
0.2 4.9 PID ARF 3PATHWAY Arf1 pathway
0.1 8.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 4.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 1.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.8 PID IL27 PATHWAY IL27-mediated signaling events
0.1 1.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 4.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 5.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 1.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.0 PID IL3 PATHWAY IL3-mediated signaling events
0.1 3.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.0 PID NOTCH PATHWAY Notch signaling pathway
0.1 0.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.8 PID FOXO PATHWAY FoxO family signaling
0.0 0.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.7 PID MYC PATHWAY C-MYC pathway
0.0 4.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 7.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 3.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 21.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
1.9 66.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
1.5 12.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.9 5.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.9 10.6 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.5 9.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.3 2.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3 5.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 3.7 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 3.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 6.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 4.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 8.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 3.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.2 3.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.2 2.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 4.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 7.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 1.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.9 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.8 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.7 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 2.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.8 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 2.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 4.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.0 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.1 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21