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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Tbr1

Z-value: 1.00

Motif logo

Transcription factors associated with Tbr1

Gene Symbol Gene ID Gene Info
ENSRNOG00000005049 T-box, brain, 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tbr1rn6_v1_chr3_+_47677720_47677720-0.141.3e-02Click!

Activity profile of Tbr1 motif

Sorted Z-values of Tbr1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_74057361 41.06 ENSRNOT00000048746
carboxypeptidase N subunit 2
chrX_-_1848904 37.76 ENSRNOT00000010984
regucalcin
chr1_+_48273611 35.49 ENSRNOT00000022254
ENSRNOT00000022068
solute carrier family 22 member 1
chr2_-_23289266 32.56 ENSRNOT00000061708
betaine-homocysteine S-methyltransferase 2
chr9_+_4072823 31.96 ENSRNOT00000085330
ENSRNOT00000061864
sulfotransferase 1C2-like
chr1_+_148240504 31.64 ENSRNOT00000085373
Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chr7_+_34326087 30.96 ENSRNOT00000006971
histidine ammonia lyase
chr15_+_57290849 30.61 ENSRNOT00000014909
carboxypeptidase B2
chr11_-_81444375 30.11 ENSRNOT00000058479
ENSRNOT00000078131
ENSRNOT00000080949
ENSRNOT00000080562
ENSRNOT00000084867
kininogen 1
chr9_-_4683160 28.45 ENSRNOT00000081413
sulfotransferase family 1C member 2
chr12_+_19196611 27.89 ENSRNOT00000001801
alpha-2-glycoprotein 1, zinc-binding
chr16_-_32868680 27.63 ENSRNOT00000015974
ENSRNOT00000082392
aminoadipate aminotransferase
chr8_-_130550388 25.62 ENSRNOT00000026355
cytochrome P450, family 8, subfamily b, polypeptide 1
chr14_-_19072677 24.45 ENSRNOT00000060548
similar to alpha-fetoprotein
chr4_+_154215250 24.29 ENSRNOT00000072465
murinoglobulin 2
chr8_-_50531423 24.00 ENSRNOT00000090985
ENSRNOT00000074942
apolipoprotein C3
chr16_-_7026540 23.00 ENSRNOT00000051751
inter-alpha trypsin inhibitor, heavy chain 1
chr19_-_41686229 22.79 ENSRNOT00000022721
tyrosine aminotransferase
chr13_-_80819218 22.05 ENSRNOT00000072922
flavin containing monooxygenase 6
chr13_+_47572219 21.67 ENSRNOT00000088449
ENSRNOT00000087664
ENSRNOT00000005853
polymeric immunoglobulin receptor
chr6_-_127653124 21.66 ENSRNOT00000047324
serpin family A member 11
chr1_-_258875572 21.65 ENSRNOT00000093005
cytochrome P450, family 2, subfamily c, polypeptide 13
chr3_+_142383278 21.60 ENSRNOT00000017742
forkhead box A2
chr6_-_129010271 20.84 ENSRNOT00000075378
serpin family A member 10
chr14_+_22142364 20.41 ENSRNOT00000002699
sulfotransferase family 1B member 1
chr6_-_127620296 20.25 ENSRNOT00000012577
serpin family A member 1
chr6_-_7058314 19.98 ENSRNOT00000045996
3-hydroxyanthranilate 3,4-dioxygenase
chr1_-_219312240 19.95 ENSRNOT00000066691
similar to hypothetical protein MGC37914
chr7_-_138483612 19.51 ENSRNOT00000085620
solute carrier family 38, member 4
chr2_+_252452269 19.38 ENSRNOT00000021970
urate oxidase
chrX_-_13601069 19.32 ENSRNOT00000004686
ornithine carbamoyltransferase
chr2_-_53185926 19.27 ENSRNOT00000081558
growth hormone receptor
chr1_+_21613148 19.21 ENSRNOT00000018695
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr10_+_109707962 19.18 ENSRNOT00000054962
ENSRNOT00000088898
glucagon receptor
chr20_-_45126062 18.81 ENSRNOT00000000720
similar to KIAA1919 protein
chr9_+_100281339 18.38 ENSRNOT00000029127
alanine-glyoxylate aminotransferase
chr16_-_81834945 17.65 ENSRNOT00000037806
coagulation factor VII
chr1_-_48559162 17.10 ENSRNOT00000080352
plasminogen
chr9_-_26707571 17.06 ENSRNOT00000080948

chr1_-_102780381 16.93 ENSRNOT00000080132
serum amyloid A4
chr9_+_95221474 16.92 ENSRNOT00000066839
UDP glucuronosyltransferase family 1 member A5
chr5_-_77408323 16.79 ENSRNOT00000046857
ENSRNOT00000046760
alpha-2u globulin PGCL5
major urinary protein 4
chr2_-_211322719 16.71 ENSRNOT00000027493
similar to KIAA1324 protein
chr9_-_4685383 16.53 ENSRNOT00000061896
sulfotransferase family 1C member 2
chr5_-_77433847 16.19 ENSRNOT00000076906
ENSRNOT00000043056
similar to alpha-2u globulin PGCL2
major urinary protein 4
chr1_-_259287684 16.00 ENSRNOT00000054724
cytochrome P450, family 2, subfamily c, polypeptide 22
chr13_+_99335020 15.85 ENSRNOT00000029787

chr13_-_80703615 15.42 ENSRNOT00000004599
flavin containing monooxygenase 4
chr5_+_60528997 15.41 ENSRNOT00000051445
glyoxylate and hydroxypyruvate reductase
chr20_-_29029905 15.41 ENSRNOT00000075682
oncoprotein induced transcript 3
chr14_+_22937421 15.16 ENSRNOT00000065079
similar to Expressed sequence AI788959
chr5_-_77342299 15.04 ENSRNOT00000075994
similar to alpha-2u-globulin
chr4_+_122244711 14.97 ENSRNOT00000038251
urocanate hydratase 1
chr5_-_77316764 14.89 ENSRNOT00000071395
ENSRNOT00000076464
major urinary protein 4
chr14_+_22724070 14.85 ENSRNOT00000089471
UDP glucuronosyltransferase 2 family, polypeptide B10
chr9_+_4817854 14.79 ENSRNOT00000040879
sulfotransferase 1C2-like
chr16_-_7758189 14.72 ENSRNOT00000026588
2-hydroxyacyl-CoA lyase 1
chr1_-_219311502 14.70 ENSRNOT00000085439
similar to hypothetical protein MGC37914
chr9_+_4807717 14.58 ENSRNOT00000092159
sulfotransferase 1C2-like
chr5_-_52767592 14.57 ENSRNOT00000048383
alpha2u globulin
chr2_-_210766501 14.46 ENSRNOT00000025800
glutathione S-transferase mu 3
chr1_-_166037424 14.30 ENSRNOT00000026115
purinergic receptor P2Y2
chr8_+_116857684 14.29 ENSRNOT00000026711
macrophage stimulating 1
chr1_+_40086470 14.22 ENSRNOT00000021895
iodotyrosine deiodinase
chr9_+_81968332 14.17 ENSRNOT00000023152
cytochrome P450, family 27, subfamily a, polypeptide 1
chr2_+_54466280 14.01 ENSRNOT00000033112
complement C6
chr17_+_8489266 13.98 ENSRNOT00000016252
leukocyte cell-derived chemotaxin 2
chr5_+_61425746 13.86 ENSRNOT00000064113
hypothetical LOC298077
chr1_+_282568287 13.76 ENSRNOT00000015997
carboxylesterase 2I
chr5_-_77725867 13.72 ENSRNOT00000076791
alpha2u globulin (LOC298111), mRNA
chr3_-_2727616 13.60 ENSRNOT00000061904
complement C8 gamma chain
chr2_-_210749991 13.57 ENSRNOT00000051261
ENSRNOT00000052403
glutathione S-transferase, mu 6-like
chr1_+_64506735 13.16 ENSRNOT00000086331
NLR family, pyrin domain containing 12
chr9_+_16825845 13.13 ENSRNOT00000074821
ly6/PLAUR domain-containing protein 4-like
chrX_+_62282212 12.98 ENSRNOT00000039568

chr3_-_176706896 12.96 ENSRNOT00000017337
protein tyrosine kinase 6
chr5_-_77903062 12.79 ENSRNOT00000073954
ENSRNOT00000059320
ENSRNOT00000089382
ENSRNOT00000076074
ENSRNOT00000074349
major urinary protein-like
alpha2u globulin (LOC298111), mRNA
chr3_+_95233874 12.72 ENSRNOT00000079743
hypothetical protein LOC691083
chr4_-_123557501 12.58 ENSRNOT00000075042
ENSRNOT00000085966
aldehyde dehydrogenase 1 family, member L1
chr7_+_14891001 12.34 ENSRNOT00000041034
cytochrome P450, family 4, subfamily f, polypeptide 4
chr14_-_80973456 12.21 ENSRNOT00000013257
HGF activator
chr5_-_77492013 12.20 ENSRNOT00000012293
alpha-2u globulin PGCL5
chrX_+_6430594 11.94 ENSRNOT00000044009
monoamine oxidase B
chr10_-_50402616 11.93 ENSRNOT00000004546
heparan sulfate-glucosamine 3-sulfotransferase 3B1
chr2_-_210738378 11.91 ENSRNOT00000025746
glutathione S-transferase, mu 6
chr10_-_71491743 11.82 ENSRNOT00000038955
uncharacterized LOC102552988
chr2_-_195423787 11.57 ENSRNOT00000071603
selenium-binding protein 1
chr8_-_21901829 11.55 ENSRNOT00000027963
angiopoietin-like 6
chr19_+_24496569 11.46 ENSRNOT00000004982
MGAT4 family, member D
chr9_-_10182676 11.45 ENSRNOT00000074894
similar to gonadotropin-regulated long chain acyl-CoA synthetase
chr13_+_75105615 11.41 ENSRNOT00000076653
tumor protein p53 inducible protein 3
chr14_-_2934571 11.37 ENSRNOT00000049772
ubiquitin-conjugating enzyme E2D 4 (putative)
chr5_+_137357674 11.29 ENSRNOT00000092813
similar to RIKEN cDNA 2610528J11
chr2_+_20857202 11.28 ENSRNOT00000078919
acyl-CoA thioesterase 12
chr12_-_41627741 11.12 ENSRNOT00000001875
serine dehydratase
chr1_+_144069638 11.07 ENSRNOT00000026870
SH3 domain-containing GRB2-like 3
chr11_-_80936524 10.84 ENSRNOT00000044591
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr2_+_127489771 10.83 ENSRNOT00000093581
inturned planar cell polarity protein
chr10_-_70118194 10.74 ENSRNOT00000009944
chaperonin containing TCP1 subunit 6B
chr2_-_196113149 10.69 ENSRNOT00000088465
selenium binding protein 1
chr8_-_68525911 10.67 ENSRNOT00000080588
ENSRNOT00000011109
IQ motif containing H
chr2_-_158133861 10.66 ENSRNOT00000090700
ventricular zone expressed PH domain-containing 1
chr18_+_69841053 10.60 ENSRNOT00000071545
ENSRNOT00000030613
ENSRNOT00000075543
maestro
chr1_-_20155960 10.50 ENSRNOT00000061389
sterile alpha motif domain containing 3
chr2_-_181900856 10.43 ENSRNOT00000082156
lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
chr5_-_115222075 10.33 ENSRNOT00000058163
ENSRNOT00000012503
cytochrome P450 2J3-like
chr9_+_95233957 10.27 ENSRNOT00000071003
UDP glucuronosyltransferase family 1 member A5
chr7_+_54859104 10.25 ENSRNOT00000087341
calcyphosine 2
chr15_+_23777856 10.10 ENSRNOT00000060847
sterile alpha motif domain containing 4A
chr9_-_95290931 10.03 ENSRNOT00000025300
DnaJ heat shock protein family (Hsp40) member B3
chr11_+_83883879 9.88 ENSRNOT00000050927
chloride channel protein 2
chr6_+_110749705 9.85 ENSRNOT00000084348
leucine rich repeat containing 74A
chr20_+_40769586 9.82 ENSRNOT00000001079
fatty acid binding protein 7
chr10_-_109747987 9.81 ENSRNOT00000054958
prolyl 4-hydroxylase subunit beta
chr1_+_72810545 9.71 ENSRNOT00000092117
protein tyrosine phosphatase, receptor type, H
chr1_-_199655147 9.67 ENSRNOT00000026979
zinc finger protein 239-like
chr1_+_222310920 9.64 ENSRNOT00000091465
MACRO domain containing 1
chr4_+_153921115 9.62 ENSRNOT00000018821
solute carrier family 6 member 12
chr1_+_166428761 9.60 ENSRNOT00000085555
StAR-related lipid transfer domain containing 10
chrX_-_65335987 9.43 ENSRNOT00000047128

chr3_-_5802129 9.31 ENSRNOT00000009555
sarcosine dehydrogenase
chr2_-_210703265 9.16 ENSRNOT00000080228
glutathione S-transferase, mu 6-like
chr6_+_111180108 9.00 ENSRNOT00000082027
glutathione S-transferase zeta 1
chr3_+_54734015 8.85 ENSRNOT00000034341
similar to protein expressed in prostate, ovary, testis, and placenta 8 isoform 2
chr18_+_46148849 8.68 ENSRNOT00000026724
proline rich 16
chr16_-_24951612 8.68 ENSRNOT00000018987
transketolase-like 2
chr13_-_37287458 8.65 ENSRNOT00000003391
insulin induced gene 2
chr8_-_103608913 8.61 ENSRNOT00000013209
plastin 1
chr2_-_19808937 8.60 ENSRNOT00000044237
ATPase H+ transporting accessory protein 1 like
chr8_+_111495331 8.59 ENSRNOT00000091275
ENSRNOT00000012162
solute carrier organic anion transporter family, member 2a1
chrX_+_110818716 8.56 ENSRNOT00000086308
ring finger protein 128, E3 ubiquitin protein ligase
chr6_+_107517668 8.53 ENSRNOT00000013753
acyl-CoA thioesterase 4
chr5_+_162127810 8.51 ENSRNOT00000038858
PRAME family member 27
chr5_+_75392790 8.49 ENSRNOT00000048457
muscle associated receptor tyrosine kinase
chr8_-_78233430 8.47 ENSRNOT00000083220
cingulin-like 1
chr10_+_110346453 8.46 ENSRNOT00000054928
testis expressed 19.1
chr8_+_117068582 8.45 ENSRNOT00000073559
aminomethyltransferase
chr7_+_54859326 8.39 ENSRNOT00000039141
calcyphosine 2
chr5_-_173483825 8.32 ENSRNOT00000085087
tubulin tyrosine ligase like 10
chr4_-_45414177 8.31 ENSRNOT00000091311
ankyrin repeat, SAM and basic leucine zipper domain containing 1
chr18_+_47613854 8.29 ENSRNOT00000025270
zinc finger protein 474
chr11_+_88699222 8.27 ENSRNOT00000084177
FYVE, RhoGEF and PH domain containing 4
chr6_+_36089433 8.25 ENSRNOT00000090438
ENSRNOT00000005731
5'-nucleotidase, cytosolic IB
chr4_+_163162211 8.13 ENSRNOT00000082537
C-type lectin domain family 1, member B
chr12_+_40466495 8.09 ENSRNOT00000001816
aldehyde dehydrogenase 2 family (mitochondrial)
chr4_-_161907767 8.07 ENSRNOT00000009557
alpha-2-macroglobulin-like 1
chr16_+_68633720 8.02 ENSRNOT00000081838
sperm motility kinase-like
chr8_+_44001096 7.96 ENSRNOT00000084164
transmembrane protein 225
chr7_+_77066955 7.94 ENSRNOT00000008700
outer dense fiber of sperm tails 1
chr5_+_133896141 7.92 ENSRNOT00000011434
PDZK1 interacting protein 1
chr19_-_860493 7.89 ENSRNOT00000078469
CKLF-like MARVEL transmembrane domain-containing protein 2B-like
chr2_-_210703606 7.89 ENSRNOT00000077563
glutathione S-transferase, mu 6-like
chr2_+_260039651 7.79 ENSRNOT00000073873
ankyrin repeat and SOCS box-containing 17
chr10_+_13196946 7.74 ENSRNOT00000071525
protease, serine, 32
chr14_-_82287706 7.66 ENSRNOT00000080695
fibroblast growth factor receptor 3
chr10_+_103395511 7.65 ENSRNOT00000004256
G protein-coupled receptor, class C, group 5, member C
chrX_-_111102464 7.65 ENSRNOT00000084176
ripply transcriptional repressor 1
chr7_+_38945836 7.64 ENSRNOT00000006455
coiled-coil glutamate-rich protein 1
chr4_+_68849033 7.59 ENSRNOT00000016912
maltase-glucoamylase
chr17_-_8607494 7.54 ENSRNOT00000016138
solute carrier family 25, member 48
chr11_+_16826399 7.52 ENSRNOT00000050701
coxsackie virus and adenovirus receptor
chr10_-_98294522 7.50 ENSRNOT00000005489
ATP binding cassette subfamily A member 8
chr11_+_82862695 7.45 ENSRNOT00000071707
ENSRNOT00000073435
chloride voltage-gated channel 2
chr11_-_32508420 7.42 ENSRNOT00000002717
potassium voltage-gated channel subfamily E regulatory subunit 1
chr16_-_70006016 7.33 ENSRNOT00000092030
predicted gene 1141
chr4_+_174181644 7.33 ENSRNOT00000011555
capping actin protein of muscle Z-line alpha subunit 3
chr9_+_81689802 7.31 ENSRNOT00000021432
villin 1
chr14_-_44613904 7.30 ENSRNOT00000003811
klotho beta
chr8_+_52829085 7.22 ENSRNOT00000007754
similar to hypothetical protein FLJ20010
chr4_-_85192834 7.19 ENSRNOT00000043752
gamma-glutamyl cyclotransferase
chr2_-_252451999 7.18 ENSRNOT00000021861
deoxyribonuclease 2 beta
chr5_-_58288125 7.16 ENSRNOT00000068752
family with sequence similarity 205, member A
chr14_-_92495894 7.15 ENSRNOT00000064483
cordon-bleu WH2 repeat protein
chr18_+_16616937 7.15 ENSRNOT00000093641
molybdenum cofactor sulfurase
chr2_+_84645084 7.14 ENSRNOT00000015448
carboxymethylenebutenolidase homolog
chr2_-_158156150 7.12 ENSRNOT00000016621
ventricular zone expressed PH domain-containing 1
chr4_-_179904844 7.02 ENSRNOT00000085386
lamin tail domain containing 1
chr14_-_3462629 6.99 ENSRNOT00000061538
bromodomain testis associated
chrX_+_16946207 6.98 ENSRNOT00000003981
similar to cysteine-rich protein 2
chr9_-_60330086 6.98 ENSRNOT00000092162
ENSRNOT00000093630
dynein, axonemal, heavy chain 7
chr1_-_100205147 6.93 ENSRNOT00000046737

chr4_+_122365093 6.91 ENSRNOT00000024011
Kruppel-like factor 15
chr17_-_32076181 6.89 ENSRNOT00000074842
leukocyte elastase inhibitor A-like
chr4_+_22084954 6.89 ENSRNOT00000090968
carnitine O-octanoyltransferase
chr1_+_152072665 6.88 ENSRNOT00000022538
RAB38, member RAS oncogene family
chr1_-_247476827 6.81 ENSRNOT00000021298
insulin-like 6
chr9_+_64066579 6.79 ENSRNOT00000013511
similar to CG31122-PA
chr3_+_143151739 6.79 ENSRNOT00000006850
cystatin 13
chr12_-_48238887 6.76 ENSRNOT00000078868
acetyl-CoA carboxylase beta
chr2_+_93669765 6.74 ENSRNOT00000045438
solute carrier family 10, member 5
chr1_+_209237233 6.70 ENSRNOT00000021537
O-6-methylguanine-DNA methyltransferase
chr13_+_49092306 6.69 ENSRNOT00000000039
NUAK family kinase 2
chr16_-_54628458 6.68 ENSRNOT00000042587
ADAM metallopeptidase domain 24
chr2_+_211880262 6.68 ENSRNOT00000038315
solute carrier family 25, member 54
chr14_-_21898284 6.68 ENSRNOT00000036314
proline rich 27
chr10_+_44804631 6.65 ENSRNOT00000040720
olfactory receptor 1460
chr11_+_44089797 6.65 ENSRNOT00000060861
ferritin heavy chain-like
chr4_+_153921900 6.65 ENSRNOT00000089482
solute carrier family 6 member 12
chr1_+_219964429 6.63 ENSRNOT00000088288
spectrin, beta, non-erythrocytic 2
chr6_+_10483308 6.60 ENSRNOT00000074516
transmembrane protein 247

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbr1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
12.6 37.8 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
10.3 31.0 GO:0043606 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) formamide metabolic process(GO:0043606)
10.2 30.6 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
9.2 27.6 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
8.0 24.0 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) regulation of high-density lipoprotein particle clearance(GO:0010982)
7.5 15.0 GO:0006548 histidine catabolic process(GO:0006548)
7.2 21.6 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
6.8 20.2 GO:0033986 response to methanol(GO:0033986)
6.5 19.5 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
6.4 19.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
6.1 18.4 GO:0046724 glycine biosynthetic process, by transamination of glyoxylate(GO:0019265) oxalic acid secretion(GO:0046724)
5.9 17.6 GO:1905225 response to 2,3,7,8-tetrachlorodibenzodioxine(GO:1904612) response to thyrotropin-releasing hormone(GO:1905225)
5.7 17.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
5.3 31.8 GO:0006572 tyrosine catabolic process(GO:0006572)
5.0 20.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
4.8 14.5 GO:0018916 nitrobenzene metabolic process(GO:0018916)
4.7 14.2 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
4.7 14.0 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
4.6 13.9 GO:0046865 isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
4.4 13.2 GO:0008592 regulation of Toll signaling pathway(GO:0008592) negative regulation of Toll signaling pathway(GO:0045751)
4.2 12.6 GO:0042560 folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
4.1 32.6 GO:0043102 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
4.0 40.0 GO:0015697 quaternary ammonium group transport(GO:0015697)
3.9 19.3 GO:0006526 arginine biosynthetic process(GO:0006526)
3.9 61.7 GO:0051923 sulfation(GO:0051923)
3.6 10.8 GO:1990743 protein sialylation(GO:1990743)
3.5 10.6 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
3.4 20.6 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
3.2 12.7 GO:0009992 cellular water homeostasis(GO:0009992)
3.0 82.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
3.0 27.2 GO:0052697 xenobiotic glucuronidation(GO:0052697)
2.8 11.4 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
2.8 8.5 GO:2000541 positive regulation of synaptic growth at neuromuscular junction(GO:0045887) regulation of protein geranylgeranylation(GO:2000539) positive regulation of protein geranylgeranylation(GO:2000541)
2.8 11.1 GO:0006565 L-serine catabolic process(GO:0006565)
2.8 8.3 GO:0018094 protein polyglycylation(GO:0018094)
2.8 11.0 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
2.6 5.2 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
2.5 12.7 GO:0061144 alveolar secondary septum development(GO:0061144)
2.3 9.3 GO:0006545 glycine biosynthetic process(GO:0006545)
2.3 4.6 GO:1903334 positive regulation of protein folding(GO:1903334)
2.2 9.0 GO:1902896 terminal web assembly(GO:1902896)
2.2 6.7 GO:0060468 prevention of polyspermy(GO:0060468)
2.2 6.6 GO:0046416 D-amino acid metabolic process(GO:0046416)
2.1 8.4 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
2.1 6.2 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
2.0 6.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348) response to butyrate(GO:1903544)
2.0 14.2 GO:0006570 tyrosine metabolic process(GO:0006570)
2.0 3.9 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
1.9 19.4 GO:0006145 purine nucleobase catabolic process(GO:0006145)
1.9 19.2 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
1.9 17.2 GO:0046449 allantoin metabolic process(GO:0000255) isoleucine metabolic process(GO:0006549) creatine metabolic process(GO:0006600) creatinine metabolic process(GO:0046449)
1.9 3.8 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
1.9 5.6 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
1.8 5.4 GO:1902463 protein localization to cell leading edge(GO:1902463)
1.8 7.1 GO:0090381 regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
1.7 10.5 GO:0070541 response to vitamin B1(GO:0010266) response to platinum ion(GO:0070541)
1.7 5.2 GO:1902214 regulation of interleukin-4-mediated signaling pathway(GO:1902214) negative regulation of apoptotic cell clearance(GO:2000426)
1.7 5.2 GO:0014028 notochord formation(GO:0014028)
1.7 5.2 GO:0016129 phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
1.7 6.9 GO:0060155 platelet dense granule organization(GO:0060155)
1.7 5.1 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
1.6 9.8 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
1.6 4.8 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
1.6 14.3 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
1.5 7.5 GO:0000066 mitochondrial ornithine transport(GO:0000066)
1.5 7.5 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
1.5 7.3 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
1.4 4.3 GO:2000118 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
1.4 7.2 GO:0048669 somite specification(GO:0001757) collateral sprouting in absence of injury(GO:0048669)
1.4 11.3 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
1.4 5.6 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
1.4 11.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
1.4 6.9 GO:0001579 medium-chain fatty acid transport(GO:0001579)
1.4 5.5 GO:0006041 glucosamine metabolic process(GO:0006041)
1.3 9.4 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
1.3 13.4 GO:0032782 bile acid secretion(GO:0032782)
1.3 16.0 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
1.3 10.4 GO:0006776 vitamin A metabolic process(GO:0006776)
1.3 6.5 GO:0097332 response to antipsychotic drug(GO:0097332)
1.3 13.8 GO:0006107 oxaloacetate metabolic process(GO:0006107)
1.2 5.0 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
1.2 32.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
1.2 7.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
1.2 24.6 GO:0015732 prostaglandin transport(GO:0015732)
1.2 4.6 GO:0051692 cellular oligosaccharide catabolic process(GO:0051692) regulation of exo-alpha-sialidase activity(GO:1903015)
1.2 3.5 GO:0006532 aspartate biosynthetic process(GO:0006532)
1.1 3.4 GO:0030091 protein repair(GO:0030091)
1.1 5.4 GO:0036233 glycine import(GO:0036233)
1.1 1.1 GO:1900453 negative regulation of long term synaptic depression(GO:1900453)
1.1 2.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.1 3.2 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
1.1 3.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
1.0 15.4 GO:0042737 drug catabolic process(GO:0042737)
1.0 3.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
1.0 7.1 GO:0007262 STAT protein import into nucleus(GO:0007262)
1.0 6.9 GO:0030035 microspike assembly(GO:0030035)
1.0 3.9 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
1.0 6.7 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.9 7.5 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
0.9 3.8 GO:0071896 protein localization to adherens junction(GO:0071896)
0.9 3.7 GO:2001190 regulation of natural killer cell degranulation(GO:0043321) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.9 9.0 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.9 5.4 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.9 33.0 GO:0042311 vasodilation(GO:0042311)
0.9 2.6 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.9 3.5 GO:0051684 maintenance of Golgi location(GO:0051684)
0.9 3.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.9 0.9 GO:1903116 positive regulation of actin filament-based movement(GO:1903116)
0.9 2.6 GO:0021570 rhombomere 4 development(GO:0021570)
0.9 2.6 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.9 2.6 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.9 2.6 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.9 0.9 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.8 2.5 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.8 22.4 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.8 3.3 GO:0060331 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.8 2.4 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.8 3.9 GO:0007343 egg activation(GO:0007343)
0.8 8.7 GO:0071501 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.8 4.6 GO:0036438 maintenance of lens transparency(GO:0036438)
0.8 3.0 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.8 2.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.8 1.5 GO:0021874 Wnt signaling pathway involved in forebrain neuroblast division(GO:0021874)
0.7 2.2 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.7 0.7 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.7 1.5 GO:0017143 insecticide metabolic process(GO:0017143)
0.7 1.5 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.7 2.2 GO:0031427 response to methotrexate(GO:0031427)
0.7 3.5 GO:0090131 mesenchyme migration(GO:0090131)
0.7 2.1 GO:0018343 protein farnesylation(GO:0018343)
0.7 3.5 GO:0034059 response to anoxia(GO:0034059)
0.7 2.7 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.7 2.0 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.7 6.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.7 2.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.7 2.0 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.7 3.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.7 20.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.6 7.1 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.6 3.2 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.6 5.1 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.6 1.3 GO:0035799 ureter maturation(GO:0035799)
0.6 9.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.6 2.5 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.6 2.5 GO:0006172 ADP biosynthetic process(GO:0006172)
0.6 7.4 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915) positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.6 1.2 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.6 3.7 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.6 1.8 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.6 5.5 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.6 2.4 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.6 1.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.6 2.9 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.6 1.8 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.6 9.8 GO:0034587 piRNA metabolic process(GO:0034587)
0.6 8.5 GO:0060134 prepulse inhibition(GO:0060134)
0.6 5.6 GO:0007220 Notch receptor processing(GO:0007220)
0.6 2.8 GO:0060005 vestibular reflex(GO:0060005)
0.5 3.8 GO:0042148 strand invasion(GO:0042148)
0.5 4.9 GO:0015816 glycine transport(GO:0015816)
0.5 7.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.5 6.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.5 5.9 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.5 5.9 GO:0046085 adenosine metabolic process(GO:0046085)
0.5 0.5 GO:0030221 basophil differentiation(GO:0030221)
0.5 2.1 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.5 14.0 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.5 4.2 GO:0006068 ethanol catabolic process(GO:0006068)
0.5 6.2 GO:0016081 synaptic vesicle docking(GO:0016081)
0.5 2.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.5 6.7 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.5 13.7 GO:0019835 cytolysis(GO:0019835)
0.5 1.5 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.5 2.5 GO:0044691 tooth eruption(GO:0044691)
0.5 7.2 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.5 1.9 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.5 6.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.5 1.4 GO:0048749 compound eye development(GO:0048749)
0.5 11.6 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.5 2.8 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278) positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.5 1.4 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.5 1.4 GO:0032532 regulation of microvillus length(GO:0032532)
0.5 7.7 GO:0001675 acrosome assembly(GO:0001675)
0.4 0.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.4 1.3 GO:0015803 branched-chain amino acid transport(GO:0015803) histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.4 7.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.4 4.4 GO:0015886 heme transport(GO:0015886)
0.4 5.3 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.4 1.3 GO:0007386 compartment pattern specification(GO:0007386)
0.4 11.3 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.4 4.3 GO:0072350 tricarboxylic acid metabolic process(GO:0072350)
0.4 0.9 GO:0051795 catagen(GO:0042637) regulation of catagen(GO:0051794) positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.4 3.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.4 0.8 GO:0060935 cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939)
0.4 2.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.4 6.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.4 2.9 GO:0043686 co-translational protein modification(GO:0043686)
0.4 17.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.4 7.0 GO:0036159 inner dynein arm assembly(GO:0036159)
0.4 2.4 GO:0048840 otolith development(GO:0048840)
0.4 4.4 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.4 2.8 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.4 5.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.4 1.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.4 1.6 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.4 3.9 GO:0006833 water transport(GO:0006833)
0.4 2.3 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.4 3.4 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.4 1.5 GO:0050917 sensory perception of umami taste(GO:0050917)
0.4 4.2 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.4 3.7 GO:0071287 cellular response to manganese ion(GO:0071287)
0.4 1.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.4 4.4 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.4 1.1 GO:0035973 aggrephagy(GO:0035973)
0.4 1.8 GO:0045218 zonula adherens maintenance(GO:0045218)
0.4 4.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.4 2.8 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.4 2.5 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.3 2.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.3 2.8 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.3 3.0 GO:0051177 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
0.3 2.6 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.3 4.0 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.3 1.6 GO:0038161 prolactin signaling pathway(GO:0038161)
0.3 0.7 GO:0071442 N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.3 13.5 GO:0006953 acute-phase response(GO:0006953)
0.3 11.8 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.3 0.9 GO:0071680 response to indole-3-methanol(GO:0071680)
0.3 9.1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.3 1.2 GO:0097117 guanylate kinase-associated protein clustering(GO:0097117)
0.3 9.0 GO:0006458 'de novo' protein folding(GO:0006458)
0.3 2.5 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.3 1.9 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.3 1.8 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.3 3.4 GO:0000338 protein deneddylation(GO:0000338)
0.3 4.6 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.3 7.3 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.3 6.0 GO:0006855 drug transmembrane transport(GO:0006855)
0.3 3.6 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.3 9.5 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.3 2.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.3 3.6 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.3 1.5 GO:0050828 regulation of liquid surface tension(GO:0050828)
0.3 3.5 GO:0033141 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.3 2.5 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.3 6.9 GO:2000757 negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.3 0.5 GO:0008355 olfactory learning(GO:0008355)
0.3 0.8 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.3 2.5 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.3 1.4 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.3 1.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.3 4.5 GO:0045332 phospholipid translocation(GO:0045332)
0.3 0.8 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.3 1.3 GO:0045297 mating plug formation(GO:0042628) single-organism reproductive behavior(GO:0044704) post-mating behavior(GO:0045297)
0.3 0.8 GO:0010446 response to alkaline pH(GO:0010446)
0.3 2.6 GO:0050746 regulation of lipoprotein metabolic process(GO:0050746)
0.3 7.2 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.3 2.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.3 0.8 GO:0035983 meiotic chromosome movement towards spindle pole(GO:0016344) response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.3 3.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.3 1.3 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.2 1.5 GO:0015871 choline transport(GO:0015871)
0.2 3.7 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.2 2.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.2 0.7 GO:0010034 response to acetate(GO:0010034)
0.2 5.7 GO:0030220 platelet formation(GO:0030220)
0.2 5.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.2 8.7 GO:0007140 male meiosis(GO:0007140)
0.2 15.4 GO:0043648 dicarboxylic acid metabolic process(GO:0043648)
0.2 0.7 GO:0036476 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.2 4.4 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.2 2.3 GO:0070255 regulation of mucus secretion(GO:0070255)
0.2 4.5 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.2 3.1 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.2 0.4 GO:0009946 proximal/distal axis specification(GO:0009946) specification of axis polarity(GO:0065001)
0.2 3.0 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.2 1.5 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.2 8.4 GO:0006739 NADP metabolic process(GO:0006739)
0.2 0.4 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.2 47.4 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.2 3.3 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.2 1.0 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.2 1.6 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.2 2.4 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.2 0.8 GO:1903999 negative regulation of eating behavior(GO:1903999)
0.2 0.8 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.2 5.6 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.2 1.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.2 2.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.2 5.1 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.2 0.9 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.2 0.6 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.2 1.5 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2 0.5 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.2 1.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.2 2.8 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.2 0.5 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.2 0.9 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.2 1.9 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 1.3 GO:0015866 ADP transport(GO:0015866)
0.2 3.5 GO:0019068 virion assembly(GO:0019068)
0.2 1.3 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.2 19.7 GO:0007286 spermatid development(GO:0007286)
0.2 1.5 GO:1903671 negative regulation of sprouting angiogenesis(GO:1903671)
0.1 1.6 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.1 2.0 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 1.7 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.1 6.0 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.1 1.4 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.5 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 2.8 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 2.9 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 0.9 GO:0072347 response to anesthetic(GO:0072347)
0.1 1.4 GO:0006265 DNA topological change(GO:0006265)
0.1 1.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 2.7 GO:0031572 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.1 0.5 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 2.3 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1 0.4 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.1 2.2 GO:0097352 autophagosome maturation(GO:0097352)
0.1 118.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.5 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1 1.3 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 2.3 GO:0032094 response to food(GO:0032094)
0.1 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.1 0.8 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 1.4 GO:0061462 protein localization to lysosome(GO:0061462)
0.1 2.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.8 GO:0006308 DNA catabolic process(GO:0006308)
0.1 1.4 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 1.0 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.1 0.7 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.1 1.6 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 2.3 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 1.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 2.9 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 2.9 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1 1.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 2.1 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 3.2 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 3.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 1.8 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.1 1.0 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 1.0 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 3.1 GO:0006638 neutral lipid metabolic process(GO:0006638)
0.0 1.3 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 1.1 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.9 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 5.4 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.6 GO:0060416 response to growth hormone(GO:0060416)
0.0 0.3 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 21.2 GO:0055114 oxidation-reduction process(GO:0055114)
0.0 0.5 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.7 GO:0006301 postreplication repair(GO:0006301)
0.0 0.3 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0 0.1 GO:1990592 protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:2000853 negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850) negative regulation of corticosterone secretion(GO:2000853)
0.0 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.3 GO:0010842 retina layer formation(GO:0010842)
0.0 0.5 GO:0048536 spleen development(GO:0048536)
0.0 0.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 1.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.9 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 17.1 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
4.0 24.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
3.9 19.3 GO:0070195 growth hormone receptor complex(GO:0070195)
3.7 11.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
2.4 26.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
2.3 14.0 GO:0005579 membrane attack complex(GO:0005579)
2.3 15.8 GO:1990357 terminal web(GO:1990357)
1.9 38.9 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
1.7 7.0 GO:0036156 inner dynein arm(GO:0036156)
1.4 12.2 GO:0071546 pi-body(GO:0071546)
1.3 2.7 GO:0002199 zona pellucida receptor complex(GO:0002199)
1.2 10.8 GO:0000138 Golgi trans cisterna(GO:0000138)
1.1 6.9 GO:0031904 endosome lumen(GO:0031904)
1.1 5.6 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.1 4.3 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
1.0 19.7 GO:0001520 outer dense fiber(GO:0001520)
1.0 5.1 GO:0044316 cone cell pedicle(GO:0044316)
1.0 14.0 GO:0033391 chromatoid body(GO:0033391)
1.0 18.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.9 22.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.8 5.5 GO:0036128 CatSper complex(GO:0036128)
0.8 90.7 GO:0072562 blood microparticle(GO:0072562)
0.8 10.7 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.7 9.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.7 0.7 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
0.7 8.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.7 3.5 GO:0072557 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.7 5.3 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.7 2.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.6 2.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.6 1.8 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.6 3.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.6 3.3 GO:0061702 inflammasome complex(GO:0061702)
0.6 2.8 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.5 6.6 GO:0032426 stereocilium tip(GO:0032426)
0.5 5.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.5 3.5 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.5 9.1 GO:0032433 filopodium tip(GO:0032433)
0.5 4.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.5 3.3 GO:0005858 axonemal dynein complex(GO:0005858)
0.5 1.4 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.4 1.8 GO:0045098 type III intermediate filament(GO:0045098)
0.4 59.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.4 4.2 GO:0070187 telosome(GO:0070187)
0.4 1.2 GO:0005896 interleukin-6 receptor complex(GO:0005896) ciliary neurotrophic factor receptor complex(GO:0070110)
0.4 2.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.4 53.9 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.4 19.5 GO:0034707 chloride channel complex(GO:0034707)
0.4 1.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.4 3.6 GO:0008091 spectrin(GO:0008091)
0.4 16.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.4 2.5 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.3 2.6 GO:0033010 paranodal junction(GO:0033010)
0.3 1.5 GO:1903768 sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
0.3 2.4 GO:0098839 postsynaptic density membrane(GO:0098839)
0.3 2.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.3 0.8 GO:0090534 calcium ion-transporting ATPase complex(GO:0090534)
0.3 2.5 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3 2.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.3 1.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.3 1.8 GO:0005915 zonula adherens(GO:0005915)
0.3 2.3 GO:0002177 manchette(GO:0002177)
0.2 3.5 GO:0005771 multivesicular body(GO:0005771)
0.2 12.1 GO:0005902 microvillus(GO:0005902)
0.2 0.7 GO:1990037 Lewy body core(GO:1990037)
0.2 1.5 GO:0071986 Ragulator complex(GO:0071986)
0.2 2.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.2 10.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 12.8 GO:0005770 late endosome(GO:0005770)
0.2 3.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.2 0.8 GO:0030478 actin cap(GO:0030478)
0.2 1.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.2 0.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 5.1 GO:0031901 early endosome membrane(GO:0031901)
0.2 54.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.2 2.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 4.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 4.1 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.2 0.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 3.8 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 3.0 GO:0005922 connexon complex(GO:0005922)
0.1 6.7 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.0 GO:0030312 external encapsulating structure(GO:0030312)
0.1 10.4 GO:0031526 brush border membrane(GO:0031526)
0.1 1.6 GO:0030904 retromer complex(GO:0030904)
0.1 13.4 GO:0005882 intermediate filament(GO:0005882)
0.1 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 3.4 GO:0034451 centriolar satellite(GO:0034451)
0.1 41.3 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 8.6 GO:0036064 ciliary basal body(GO:0036064)
0.1 3.2 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.5 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.9 GO:0061700 GATOR2 complex(GO:0061700)
0.1 145.0 GO:0005615 extracellular space(GO:0005615)
0.1 1.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 29.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 1.3 GO:0016528 sarcoplasm(GO:0016528)
0.1 0.7 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 10.0 GO:0005923 bicellular tight junction(GO:0005923)
0.1 0.9 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 1.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 51.3 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 6.7 GO:0030141 secretory granule(GO:0030141)
0.1 0.5 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 1.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 1.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 72.5 GO:0005739 mitochondrion(GO:0005739)
0.1 0.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.5 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.4 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.5 GO:0034706 sodium channel complex(GO:0034706)
0.1 1.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.9 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 3.6 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.8 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.2 GO:0005871 kinesin complex(GO:0005871)
0.0 1.4 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 1.2 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.6 GO:0005903 brush border(GO:0005903)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
13.3 40.0 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
12.6 62.9 GO:0005550 pheromone binding(GO:0005550)
9.7 48.7 GO:0016841 ammonia-lyase activity(GO:0016841)
9.2 27.6 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
8.0 24.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
7.6 22.8 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
6.4 19.2 GO:0004528 phosphodiesterase I activity(GO:0004528)
4.9 39.3 GO:0008172 S-methyltransferase activity(GO:0008172)
4.8 19.3 GO:0004903 growth hormone receptor activity(GO:0004903)
4.8 19.2 GO:0004967 glucagon receptor activity(GO:0004967)
3.8 15.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
3.7 11.2 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
3.7 18.4 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
3.5 10.5 GO:0004655 porphobilinogen synthase activity(GO:0004655)
3.5 3.5 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
3.1 37.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
3.0 12.0 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
2.9 20.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
2.8 22.3 GO:0008430 selenium binding(GO:0008430)
2.8 8.3 GO:0070735 protein-glycine ligase activity(GO:0070735)
2.8 19.4 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
2.8 11.0 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
2.7 82.3 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
2.7 10.8 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
2.7 18.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
2.6 5.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
2.5 15.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
2.5 14.7 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
2.4 9.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
2.3 6.9 GO:0016414 carnitine O-octanoyltransferase activity(GO:0008458) O-octanoyltransferase activity(GO:0016414)
2.3 6.9 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
2.2 86.8 GO:0004364 glutathione transferase activity(GO:0004364)
2.1 6.4 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
2.0 6.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
2.0 8.1 GO:0070404 NADH binding(GO:0070404)
2.0 11.9 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.9 59.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
1.9 7.6 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
1.9 11.4 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
1.9 7.6 GO:0016160 amylase activity(GO:0016160)
1.9 39.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
1.8 7.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
1.8 7.3 GO:0036132 13-prostaglandin reductase activity(GO:0036132)
1.8 7.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
1.8 12.6 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
1.8 7.1 GO:0008265 Mo-molybdopterin cofactor sulfurase activity(GO:0008265)
1.7 20.7 GO:0019763 immunoglobulin receptor activity(GO:0019763)
1.6 6.4 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
1.6 12.7 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
1.6 6.2 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
1.5 4.6 GO:0017042 glycosylceramidase activity(GO:0017042)
1.4 18.7 GO:0042301 phosphate ion binding(GO:0042301)
1.4 14.4 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
1.4 7.0 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
1.4 4.2 GO:0019807 aspartoacylase activity(GO:0019807)
1.4 74.3 GO:0008146 sulfotransferase activity(GO:0008146)
1.3 5.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
1.3 6.5 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.3 2.5 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
1.1 7.9 GO:0031404 chloride ion binding(GO:0031404)
1.1 6.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.1 11.9 GO:0008131 primary amine oxidase activity(GO:0008131)
1.1 8.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
1.1 7.4 GO:0031433 telethonin binding(GO:0031433)
1.0 6.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.0 14.6 GO:0070402 NADPH binding(GO:0070402)
1.0 10.4 GO:0019841 retinol binding(GO:0019841)
1.0 7.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
1.0 5.1 GO:0016918 retinal binding(GO:0016918)
1.0 118.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
1.0 2.9 GO:0016509 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
1.0 5.8 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
1.0 2.9 GO:0047708 biotinidase activity(GO:0047708)
0.9 18.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.9 7.5 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.9 2.6 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.9 4.4 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.9 13.0 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.8 5.0 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.8 17.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.8 5.0 GO:0070728 leucine binding(GO:0070728)
0.8 4.1 GO:0046790 virion binding(GO:0046790)
0.8 2.5 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.8 17.2 GO:0019825 oxygen binding(GO:0019825)
0.8 2.4 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.8 4.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.8 3.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.8 10.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.8 16.8 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.8 9.3 GO:0005542 folic acid binding(GO:0005542)
0.8 13.9 GO:0001848 complement binding(GO:0001848)
0.7 2.2 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.7 4.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.7 1.5 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.7 8.6 GO:0015245 fatty acid transporter activity(GO:0015245)
0.7 11.4 GO:0010181 FMN binding(GO:0010181)
0.7 2.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.7 2.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.7 2.8 GO:0002046 opsin binding(GO:0002046)
0.7 2.8 GO:0015057 thrombin receptor activity(GO:0015057)
0.7 12.3 GO:0070330 aromatase activity(GO:0070330)
0.7 5.3 GO:0071253 connexin binding(GO:0071253)
0.7 10.6 GO:0070492 oligosaccharide binding(GO:0070492)
0.6 5.8 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.6 3.8 GO:0000150 recombinase activity(GO:0000150)
0.6 1.8 GO:0070698 type I activin receptor binding(GO:0070698)
0.6 15.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.6 1.7 GO:0030977 taurine binding(GO:0030977)
0.5 1.6 GO:0004925 prolactin receptor activity(GO:0004925)
0.5 15.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.5 11.2 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.5 1.0 GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294)
0.5 3.0 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.5 1.5 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.5 5.3 GO:0039706 co-receptor binding(GO:0039706)
0.5 7.9 GO:0001594 trace-amine receptor activity(GO:0001594)
0.5 1.8 GO:0048408 epidermal growth factor binding(GO:0048408)
0.5 1.8 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.5 9.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.5 7.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.4 30.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.4 1.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.4 5.7 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.4 2.6 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.4 11.2 GO:0030371 translation repressor activity(GO:0030371)
0.4 18.6 GO:0016836 hydro-lyase activity(GO:0016836)
0.4 1.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.4 0.8 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.4 2.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.4 2.4 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.4 1.2 GO:0004774 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.4 2.3 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846) diacylglycerol O-acyltransferase activity(GO:0004144)
0.4 1.9 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.4 1.5 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.4 5.9 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.4 0.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.4 5.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.4 1.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.4 12.0 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.4 1.8 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.4 3.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.3 5.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.3 1.0 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.3 6.4 GO:0008199 ferric iron binding(GO:0008199)
0.3 7.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.3 6.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.3 3.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.3 3.5 GO:0016805 dipeptidase activity(GO:0016805)
0.3 3.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.3 10.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.3 2.8 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.3 1.5 GO:0033041 sweet taste receptor activity(GO:0033041)
0.3 3.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.3 2.0 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.3 2.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.3 3.9 GO:0015250 water channel activity(GO:0015250)
0.3 1.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.3 5.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.3 11.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.3 4.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.3 1.3 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.3 0.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.3 2.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.3 1.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 3.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 3.0 GO:0005243 gap junction channel activity(GO:0005243)
0.2 2.2 GO:0008494 translation activator activity(GO:0008494) translation regulator activity, nucleic acid binding(GO:0090079)
0.2 0.7 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.2 0.7 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 1.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.2 1.6 GO:0035375 zymogen binding(GO:0035375)
0.2 1.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 8.2 GO:0019213 deacetylase activity(GO:0019213)
0.2 47.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 32.6 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.2 6.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 1.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 2.9 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 13.5 GO:0051082 unfolded protein binding(GO:0051082)
0.2 1.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.2 1.0 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.2 0.8 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.2 1.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2 2.0 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.2 0.6 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.2 73.7 GO:0005549 odorant binding(GO:0005549)
0.2 0.7 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.2 1.8 GO:0070097 delta-catenin binding(GO:0070097)
0.2 1.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 1.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.2 2.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.2 1.9 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.2 10.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 1.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.2 18.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 4.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 1.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.2 1.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 12.7 GO:0046332 SMAD binding(GO:0046332)
0.1 1.3 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 3.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.9 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.9 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 1.2 GO:0050815 phosphoserine binding(GO:0050815)
0.1 12.5 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 1.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 1.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.8 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 1.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 3.2 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.1 0.9 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.5 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 1.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 3.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 3.2 GO:0030552 cAMP binding(GO:0030552)
0.1 2.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 2.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 3.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 3.3 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 2.8 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.1 1.4 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.1 4.9 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 1.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 1.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.8 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 1.2 GO:0004601 peroxidase activity(GO:0004601)
0.1 1.9 GO:0015485 cholesterol binding(GO:0015485)
0.1 44.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 1.0 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.8 GO:0003774 motor activity(GO:0003774)
0.0 1.3 GO:0016859 cis-trans isomerase activity(GO:0016859)
0.0 0.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 2.1 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.7 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 1.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.6 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.2 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.7 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.0 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 209.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.8 44.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.5 11.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.4 7.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.4 12.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.3 6.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.3 4.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.3 7.5 PID FGF PATHWAY FGF signaling pathway
0.2 6.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 8.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.2 10.8 NABA COLLAGENS Genes encoding collagen proteins
0.2 2.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.2 3.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 1.5 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.2 2.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 3.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 2.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 3.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 4.4 PID AURORA A PATHWAY Aurora A signaling
0.1 2.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 3.6 PID ATR PATHWAY ATR signaling pathway
0.1 6.2 PID P73PATHWAY p73 transcription factor network
0.1 5.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 0.8 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 1.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 1.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 1.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.5 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 2.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.8 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 47.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
5.0 65.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
4.4 40.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
3.0 36.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
2.3 42.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
2.0 33.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
1.8 17.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
1.6 28.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
1.3 7.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
1.1 20.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
1.0 10.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
1.0 8.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.9 20.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.9 8.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.9 18.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.9 18.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.9 24.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.9 11.6 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.8 13.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.8 12.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.7 8.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.7 130.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.6 7.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.6 8.3 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.6 10.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.6 12.9 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.6 5.6 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.6 18.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.5 13.7 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.5 11.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.5 3.8 REACTOME OPSINS Genes involved in Opsins
0.5 5.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.4 15.2 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.4 6.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.4 11.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.4 3.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.4 2.3 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.4 15.9 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.3 3.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.3 3.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 27.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.3 4.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.3 2.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.3 2.4 REACTOME DEFENSINS Genes involved in Defensins
0.3 15.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.3 3.2 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.3 8.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 5.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 4.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 10.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 2.5 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.2 8.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 2.9 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 4.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 1.0 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.2 1.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.2 3.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 10.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 0.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 1.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 4.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.3 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 8.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 1.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.8 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 3.8 REACTOME KINESINS Genes involved in Kinesins
0.1 4.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 2.0 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.1 1.0 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 1.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 6.1 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.1 1.5 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 1.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 1.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.8 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.1 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.1 0.6 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 7.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 2.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.1 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.1 0.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.8 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo