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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Taf1

Z-value: 2.46

Motif logo

Transcription factors associated with Taf1

Gene Symbol Gene ID Gene Info
ENSRNOG00000002565 Taf1

Activity profile of Taf1 motif

Sorted Z-values of Taf1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_49280901 50.57 ENSRNOT00000021390
CD3g molecule
chr8_-_49308806 41.30 ENSRNOT00000047291
CD3e molecule
chr3_+_112531703 41.28 ENSRNOT00000041727
protein CASC5-like
chr2_+_165601007 38.28 ENSRNOT00000013931
structural maintenance of chromosomes 4
chr19_+_37600148 30.65 ENSRNOT00000023853
CCCTC-binding factor
chr17_+_9595761 26.04 ENSRNOT00000089990
family with sequence similarity 193, member B
chr2_-_123281856 25.78 ENSRNOT00000079745
cyclin A2
chr2_+_53859737 24.75 ENSRNOT00000065313
3-oxoacid CoA transferase 1
chr12_-_30566032 23.30 ENSRNOT00000093378
glioblastoma amplified sequence
chr16_-_36080191 22.44 ENSRNOT00000017635
high mobility group box 2-like 1
chrX_-_63203643 22.38 ENSRNOT00000065194
ENSRNOT00000076974
zinc finger protein X-linked
chr6_+_51662224 22.01 ENSRNOT00000060006
coiled-coil domain containing 71-like
chr4_-_8255379 20.93 ENSRNOT00000076583
ENSRNOT00000076950
ENSRNOT00000076633
lysine methyltransferase 2E
chr14_+_11199404 20.69 ENSRNOT00000003106
heterogeneous nuclear ribonucleoprotein D-like
chrX_+_37469937 20.53 ENSRNOT00000008938
ribosomal protein S6 kinase A3
chrX_-_114232939 20.46 ENSRNOT00000042639
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr1_-_282251257 20.38 ENSRNOT00000015186
peroxiredoxin 3
chr19_+_26142720 19.92 ENSRNOT00000005270
similar to RIKEN cDNA 2310036O22
chr1_-_198128857 19.66 ENSRNOT00000026496
coronin 1A
chr6_-_103313074 19.52 ENSRNOT00000083677
zinc finger protein 36, C3H type-like 1
chrX_+_15098904 19.45 ENSRNOT00000007367
ENSRNOT00000087033
RNA binding motif (RNP1, RRM) protein 3
chr7_+_11724962 19.35 ENSRNOT00000026551
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr1_-_261051498 19.00 ENSRNOT00000071417
Rho GTPase activating protein 19
chr7_-_109205354 18.98 ENSRNOT00000068291
zinc finger and AT hook domain containing
chrX_-_79909678 18.87 ENSRNOT00000050336
bromodomain and WD repeat domain containing 3
chr1_-_72621519 18.81 ENSRNOT00000058943
ribosomal protein L28
chrX_+_156812064 18.67 ENSRNOT00000077142
host cell factor C1
chr1_-_198476476 18.50 ENSRNOT00000027525
kinesin family member 22
chr16_+_19127724 18.47 ENSRNOT00000018960
epidermal growth factor receptor pathway substrate 15-like 1
chr18_+_51785111 18.32 ENSRNOT00000019351
lamin B1
chr7_-_109205194 18.27 ENSRNOT00000093145
zinc finger and AT hook domain containing
chr14_-_2700977 18.00 ENSRNOT00000000086
metal response element binding transcription factor 2
chr16_-_7290561 17.91 ENSRNOT00000036910
nischarin
chr12_+_23151180 17.89 ENSRNOT00000059486
cut-like homeobox 1
chr8_-_118926613 17.65 ENSRNOT00000056130
neurobeachin-like 2
chr8_+_48925604 17.56 ENSRNOT00000077445
DEAD-box helicase 6
chr11_+_84094520 17.56 ENSRNOT00000046642
ribosomal protein S15A-like 2
chr4_-_78924181 17.44 ENSRNOT00000012325
transformer 2 alpha homolog
chr2_-_189573280 17.37 ENSRNOT00000022897
ribosomal protein S27
chr19_+_25969255 17.10 ENSRNOT00000004370
phenylalanyl-tRNA synthetase, alpha subunit
chr1_+_87009730 17.09 ENSRNOT00000027537
enoyl-CoA hydratase 1
chr4_+_157726941 17.04 ENSRNOT00000025081
vesicle-associated membrane protein 1
chr9_-_10471176 17.04 ENSRNOT00000089164
scaffold attachment factor B
chr4_+_8256611 16.98 ENSRNOT00000061894

chr2_+_54857688 16.70 ENSRNOT00000017626
protein kinase AMP-activated catalytic subunit alpha 1
chr4_+_118207862 16.67 ENSRNOT00000085787
ENSRNOT00000023103
TIA1 cytotoxic granule-associated RNA binding protein
chr3_+_33641616 16.58 ENSRNOT00000051953
enhancer of polycomb homolog 2
chr1_+_174702373 16.58 ENSRNOT00000013733
zinc finger protein 143
chrX_+_156999826 16.48 ENSRNOT00000081819
isocitrate dehydrogenase 3 (NAD), gamma
chr1_-_164977633 16.48 ENSRNOT00000029629
ring finger protein 169
chr8_+_78858570 16.43 ENSRNOT00000089335
zinc finger protein 280D
chr2_-_30340103 16.42 ENSRNOT00000024023
ENSRNOT00000067722
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
chr15_-_33656089 16.28 ENSRNOT00000024186
myosin heavy chain 7
chr13_+_96219853 16.21 ENSRNOT00000006154
COX20 cytochrome C oxidase assembly factor
chr12_-_39769480 16.18 ENSRNOT00000036137
PTC7 protein phosphatase homolog
chr8_+_116343096 16.14 ENSRNOT00000022092
interferon-related developmental regulator 2
chr6_-_28663233 16.01 ENSRNOT00000070979
centromere protein O
chr19_-_55423052 16.00 ENSRNOT00000019528
ENSRNOT00000079641
galactosamine (N-acetyl)-6-sulfatase
chr1_-_100887853 15.99 ENSRNOT00000027675
mediator complex subunit 25
chr8_+_87486427 15.96 ENSRNOT00000015741
SUMO1/sentrin specific peptidase 6
chr1_+_85112834 15.90 ENSRNOT00000026107
dual specificity tyrosine phosphorylation regulated kinase 1B
chr9_+_17120759 15.89 ENSRNOT00000025787
RNA polymerase I subunit C
chr9_-_10801140 15.88 ENSRNOT00000072771
fem-1 homolog A
chr14_-_93042182 15.84 ENSRNOT00000005432
protein arginine methyltransferase 1-like
chr13_-_41738622 15.78 ENSRNOT00000004520
ENSRNOT00000084552
ARP3 actin related protein 3 homolog
chr13_-_110077946 15.77 ENSRNOT00000000078
protein phosphatase 2, regulatory subunit B', alpha
chr2_-_78283473 15.67 ENSRNOT00000087246

chr14_+_24129592 15.57 ENSRNOT00000040647
similar to 60S ribosomal protein L23a
chr3_+_79570625 15.50 ENSRNOT00000078278
ENSRNOT00000009687
formin binding protein 4
chrX_+_71174699 15.43 ENSRNOT00000076957
ENSRNOT00000090192
ENSRNOT00000040334
mediator complex subunit 12
chr1_+_85162452 15.43 ENSRNOT00000093347
p21 (RAC1) activated kinase 4
chr14_+_82093837 15.37 ENSRNOT00000021593
negative elongation factor complex member A
chr20_-_10407554 15.36 ENSRNOT00000074081
U2 small nuclear RNA auxiliary factor 1
chr10_-_108425206 15.32 ENSRNOT00000073140
eukaryotic translation initiation factor 4A3
chr9_-_10471009 15.29 ENSRNOT00000072868
scaffold attachment factor B
chr10_-_88533171 15.22 ENSRNOT00000024321
DnaJ heat shock protein family (Hsp40) member C7
chr8_+_132032944 15.15 ENSRNOT00000089278
kinesin family member 15
chr10_+_85257876 15.14 ENSRNOT00000014752
mitochondrial ribosomal protein L45
chr1_-_101123402 15.04 ENSRNOT00000027976

chr1_-_187766670 15.01 ENSRNOT00000092513
ENSRNOT00000092282
ribosomal protein S15a
chrX_-_159891326 15.00 ENSRNOT00000001154
RNA binding motif protein, X-linked
chr6_+_128738388 14.95 ENSRNOT00000050204
ribosomal protein L6, pseudogene 1
chr1_-_266086299 14.91 ENSRNOT00000026609
CUE domain containing 2
chr6_+_8346704 14.90 ENSRNOT00000092218

chr1_+_193076430 14.86 ENSRNOT00000086492
ENSRNOT00000017885
trinucleotide repeat containing 6a
chr6_-_11274932 14.77 ENSRNOT00000021538
mutS homolog 2
chr10_+_75365822 14.63 ENSRNOT00000055705
vascular endothelial zinc finger 1
chr5_+_164923302 14.59 ENSRNOT00000042285
60S ribosomal protein L35a
chr8_-_128009951 14.56 ENSRNOT00000018056
oxidative-stress responsive 1
chr13_-_89594738 14.35 ENSRNOT00000004641
translocase of outer mitochondrial membrane 40 like
chr7_-_34485034 14.33 ENSRNOT00000007351
small nuclear ribonucleoprotein polypeptide F
chr1_-_142615673 14.31 ENSRNOT00000018021
IQ motif containing GTPase activating protein 1
chr2_+_119197239 14.23 ENSRNOT00000048030
ubiquitin specific peptidase 13
chr6_-_2886465 14.13 ENSRNOT00000038448
serine and arginine rich splicing factor 7
chr12_-_37574750 14.09 ENSRNOT00000066253
lysine methyltransferase 5A
chr1_-_90246265 14.09 ENSRNOT00000078585
ENSRNOT00000030186
LSM14A mRNA processing body assembly factor
chr8_-_96266342 14.06 ENSRNOT00000078891
synaptotagmin binding, cytoplasmic RNA interacting protein
chr5_+_1417478 14.06 ENSRNOT00000008153
ENSRNOT00000085564
junctophilin 1
chr2_-_139528162 14.05 ENSRNOT00000014317
solute carrier family 7 member 11
chr7_-_14303055 13.99 ENSRNOT00000008963
bromodomain containing 4
chr5_-_157820889 13.94 ENSRNOT00000024326
MRT4 homolog, ribosome maturation factor
chr4_+_122282279 13.93 ENSRNOT00000038244
ZXD family zinc finger C
chr4_-_159697207 13.88 ENSRNOT00000086440
cyclin D2
chr10_-_85684138 13.84 ENSRNOT00000017989
phosphatidylinositol-5-phosphate 4-kinase type 2 beta
chr1_-_101819478 13.80 ENSRNOT00000056181
glutamate-rich WD repeat containing 1
chr13_+_96303703 13.79 ENSRNOT00000084718
ENSRNOT00000029723
EF-hand calcium binding domain 2
chr6_-_91518996 13.78 ENSRNOT00000005835
DNA polymerase epsilon 2, accessory subunit
chr3_+_80081647 13.75 ENSRNOT00000057161
ADP-ribosylation factor GTPase activating protein 2
chr18_+_27424328 13.70 ENSRNOT00000033784
kinesin family member 20A
chr20_+_12944786 13.70 ENSRNOT00000048218
pericentrin
chr4_+_157230769 13.70 ENSRNOT00000091464
ENSRNOT00000017472
prohibitin 2
chr16_+_82184387 13.69 ENSRNOT00000089329
ENSRNOT00000068416
tubulin, gamma complex associated protein 3
chr9_-_66627007 13.68 ENSRNOT00000049571

chr8_+_21669236 13.67 ENSRNOT00000027818
peptidylprolyl cis/trans isomerase, NIMA-interacting 1
chr2_-_232373409 13.65 ENSRNOT00000041479

chr6_-_86822094 13.62 ENSRNOT00000006531
FK506 binding protein 3
chr17_-_14687408 13.61 ENSRNOT00000088542

chr18_+_24584900 13.56 ENSRNOT00000017075
WD repeat domain 33
chr10_-_70259553 13.51 ENSRNOT00000011320
notchless homolog 1
chr11_+_82415995 13.49 ENSRNOT00000051772

chr8_+_69121682 13.45 ENSRNOT00000013461
ribosomal protein L4
chr1_-_89382463 13.40 ENSRNOT00000087381
upstream transcription factor 2, c-fos interacting
chr14_-_34115273 13.40 ENSRNOT00000032156
centrosomal protein 135
chr8_+_61603991 13.39 ENSRNOT00000065156

chr20_+_46428124 13.27 ENSRNOT00000000327
forkhead box O3
chr16_+_86600877 13.25 ENSRNOT00000057347
arginine and glutamate rich 1
chr1_+_221756286 13.19 ENSRNOT00000028636
glycogen phosphorylase, muscle associated
chr19_+_21049145 13.18 ENSRNOT00000084965

chr10_-_89338739 13.13 ENSRNOT00000073923
prostaglandin E synthase 3 like
chr18_+_65155685 13.12 ENSRNOT00000081797
transcription factor 4
chr10_+_730247 13.12 ENSRNOT00000083714
FGFR1OP N-terminal like
chr2_-_238803024 13.12 ENSRNOT00000046775
tet methylcytosine dioxygenase 2
chr19_-_57614558 13.11 ENSRNOT00000025948
similar to RIKEN cDNA 0610039J04
chr13_-_89661150 13.09 ENSRNOT00000058390
ubiquitin specific peptidase 21
chr13_-_30800451 13.09 ENSRNOT00000046791
ribosomal protein L21
chr3_-_37854561 13.07 ENSRNOT00000076095
nebulin
chr4_+_594882 13.01 ENSRNOT00000033377
RNA binding motif protein 33
chr6_+_42092467 12.98 ENSRNOT00000060499
E2F transcription factor 6
chr4_-_100883038 12.97 ENSRNOT00000041880
thymosin, beta 10-like
chr10_-_90657185 12.95 ENSRNOT00000003685
coiled-coil domain containing 43
chr5_+_35991068 12.90 ENSRNOT00000061139
PNN interacting serine and arginine rich protein
chr5_+_57657909 12.88 ENSRNOT00000073017
similar to ribosomal protein S13
chr7_+_117409576 12.85 ENSRNOT00000017067
cytochrome c-1
chr10_+_59173268 12.84 ENSRNOT00000013486
ubiquitin-conjugating enzyme E2G 1
chr6_+_2569013 12.79 ENSRNOT00000008988
atlastin GTPase 2
chr1_-_164849749 12.73 ENSRNOT00000024772
signal peptidase complex subunit 2
chr15_+_37418885 12.67 ENSRNOT00000043836
similar to 60S ribosomal protein L23a
chr7_+_123102493 12.60 ENSRNOT00000038612
aconitase 2
chr7_+_120923274 12.53 ENSRNOT00000049247
GTP binding protein 1
chr8_-_105088401 12.52 ENSRNOT00000073068
40S ribosomal protein S17-like
chr9_+_42315682 12.52 ENSRNOT00000071995

chr14_+_84393182 12.51 ENSRNOT00000008355
splicing factor 3a, subunit 1
chr19_-_10596851 12.48 ENSRNOT00000021716
coenzyme Q9
chr2_-_30458542 12.46 ENSRNOT00000072926
NLR family, apoptosis inhibitory protein 6
chr9_+_17086475 12.45 ENSRNOT00000025660
tight junction associated protein 1
chr5_-_169160987 12.44 ENSRNOT00000055487
THAP domain containing 3
chr15_+_30735921 12.43 ENSRNOT00000078887

chr13_-_69172643 12.42 ENSRNOT00000049703

chr3_-_24601063 12.41 ENSRNOT00000037043
40S ribosomal protein S17-like
chr1_-_225128740 12.41 ENSRNOT00000026897
retinal outer segment membrane protein 1
chr6_+_12253788 12.40 ENSRNOT00000061675
protein phosphatase 1, regulatory subunit 21
chr1_-_199320727 12.40 ENSRNOT00000022452
zinc finger protein 668
chr2_-_196270826 12.29 ENSRNOT00000028609
phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha
chr10_+_61772449 12.29 ENSRNOT00000004058
SMG6 nonsense mediated mRNA decay factor
chrX_+_71540895 12.26 ENSRNOT00000004692
ENSRNOT00000082967
O-linked N-acetylglucosamine (GlcNAc) transferase
chr2_+_187415262 12.21 ENSRNOT00000056923
G patch domain containing 4
chr2_-_34419428 12.21 ENSRNOT00000048123

chr10_+_56591292 12.13 ENSRNOT00000023379
CTD nuclear envelope phosphatase 1
chr5_-_50362344 12.08 ENSRNOT00000035808
zinc finger protein 292
chrX_+_10430847 12.08 ENSRNOT00000047936
ribosomal protein L21
chr16_+_83206004 12.08 ENSRNOT00000018870
ankyrin repeat domain 10
chr20_+_3827367 12.06 ENSRNOT00000079967
retinoid X receptor beta
chr17_-_9952898 12.03 ENSRNOT00000060928
nuclear receptor binding SET domain protein 1
chr5_-_154223536 12.02 ENSRNOT00000012258
proline-rich nuclear receptor coactivator 2
chr2_-_211715311 11.97 ENSRNOT00000027738
pre-mRNA processing factor 38B
chr12_-_39641285 11.97 ENSRNOT00000001729
anaphase promoting complex subunit 7
chr11_-_66695353 11.96 ENSRNOT00000063995
DNA polymerase theta
chr10_-_104155717 11.95 ENSRNOT00000089894
golgi associated, gamma adaptin ear containing, ARF binding protein 3
chr5_+_172367398 11.94 ENSRNOT00000019028
pantothenate kinase 4
chr18_+_59096643 11.94 ENSRNOT00000025325
WD repeat domain 7
chr1_-_101046208 11.90 ENSRNOT00000091711
proline rich 12
chr8_+_50310405 11.90 ENSRNOT00000073507
SIK family kinase 3
chr9_-_117867557 11.89 ENSRNOT00000056321

chr4_+_153385205 11.85 ENSRNOT00000016561
BCL2 like 13
chr5_+_140712583 11.84 ENSRNOT00000019587
tRNA isopentenyltransferase 1
chr15_-_93667116 11.77 ENSRNOT00000093184
F-box and leucine-rich repeat protein 3
chr13_-_51784639 11.75 ENSRNOT00000089068
protein phosphatase 1, regulatory subunit 12B
chr2_-_189899103 11.73 ENSRNOT00000010455
chromatin target of PRMT1
chr13_+_109669680 11.72 ENSRNOT00000068623
NSL1, MIS12 kinetochore complex component
chr6_-_111477090 11.69 ENSRNOT00000016389
alkB homolog 1, histone H2A dioxygenase
chr1_+_167538263 11.68 ENSRNOT00000074058
ribonucleotide reductase catalytic subunit M1
chr10_-_72556564 11.65 ENSRNOT00000048373

chr2_+_196594303 11.63 ENSRNOT00000064442
ENSRNOT00000044738
aryl hydrocarbon receptor nuclear translocator
chr7_+_144865608 11.62 ENSRNOT00000091596
ENSRNOT00000055285
heterogeneous nuclear ribonucleoprotein A1
chr1_+_196095214 11.61 ENSRNOT00000080741
similar to ribosomal protein S15a
chr1_+_225163391 11.61 ENSRNOT00000027305
eukaryotic translation elongation factor 1 gamma
chr19_+_25946979 11.53 ENSRNOT00000004027
GADD45G interacting protein 1
chr1_+_265809754 11.51 ENSRNOT00000025221
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr4_-_27331508 11.50 ENSRNOT00000090751
ENSRNOT00000010118
A-kinase anchoring protein 9
chr5_+_125896725 11.48 ENSRNOT00000029228
ubiquitin specific peptidase 24

Network of associatons between targets according to the STRING database.

First level regulatory network of Taf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.2 24.7 GO:0046952 ketone body catabolic process(GO:0046952)
7.7 38.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
7.3 21.8 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
6.9 41.3 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
6.6 39.5 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
6.2 24.7 GO:1904580 regulation of intracellular mRNA localization(GO:1904580)
5.8 17.4 GO:0070084 protein initiator methionine removal(GO:0070084)
5.6 33.5 GO:0006102 isocitrate metabolic process(GO:0006102)
5.4 16.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444) response to 3,3',5-triiodo-L-thyronine(GO:1905242) cellular response to 3,3',5-triiodo-L-thyronine(GO:1905243)
5.3 15.8 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344) regulation of bleb assembly(GO:1904170)
4.9 14.6 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
4.7 18.7 GO:0019042 viral latency(GO:0019042) release from viral latency(GO:0019046)
4.5 31.3 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
4.4 13.3 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
4.4 17.6 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
4.4 13.1 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
4.3 21.6 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
4.3 25.8 GO:0071314 cellular response to cocaine(GO:0071314)
4.3 4.3 GO:0097034 mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
4.2 16.7 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
4.1 20.4 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
4.1 12.2 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
4.0 24.0 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
4.0 16.0 GO:0090234 regulation of kinetochore assembly(GO:0090234)
3.9 23.6 GO:0090367 negative regulation of mRNA modification(GO:0090367)
3.9 11.7 GO:0042245 RNA repair(GO:0042245)
3.8 30.6 GO:0010216 maintenance of DNA methylation(GO:0010216)
3.8 30.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
3.8 11.3 GO:0010265 SCF complex assembly(GO:0010265)
3.6 10.8 GO:0006344 maintenance of chromatin silencing(GO:0006344)
3.6 14.4 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
3.6 14.2 GO:0036506 maintenance of unfolded protein(GO:0036506) protein K6-linked deubiquitination(GO:0044313) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
3.6 10.7 GO:1903699 tarsal gland development(GO:1903699)
3.5 17.6 GO:0070889 platelet alpha granule organization(GO:0070889)
3.5 10.6 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
3.5 10.5 GO:0097101 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
3.5 34.7 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
3.4 13.5 GO:1903936 cellular response to sodium arsenite(GO:1903936)
3.3 19.7 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
3.2 19.2 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086)
3.2 28.7 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
3.2 22.2 GO:0070269 pyroptosis(GO:0070269)
3.2 12.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
3.1 12.5 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
3.1 15.6 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
3.1 15.4 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
3.1 18.5 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
3.1 9.2 GO:0006552 leucine catabolic process(GO:0006552)
3.0 12.0 GO:0097681 double-strand break repair via alternative nonhomologous end joining(GO:0097681)
3.0 14.9 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
2.9 8.6 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
2.9 8.6 GO:0046601 positive regulation of centriole replication(GO:0046601)
2.8 8.5 GO:0090669 telomerase RNA stabilization(GO:0090669)
2.8 8.5 GO:0051697 protein delipidation(GO:0051697)
2.8 8.3 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
2.8 13.8 GO:0042276 error-prone translesion synthesis(GO:0042276)
2.7 16.4 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
2.7 19.0 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
2.7 8.1 GO:0080033 cellular response to carbon monoxide(GO:0071245) cellular response to nitrite(GO:0071250) response to nitrite(GO:0080033)
2.7 8.1 GO:0003162 atrioventricular node development(GO:0003162)
2.7 13.5 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
2.7 10.7 GO:0070475 rRNA base methylation(GO:0070475)
2.6 7.9 GO:0071038 nuclear mRNA surveillance of mRNA 3'-end processing(GO:0071031) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription(GO:0071049)
2.6 7.8 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
2.6 15.6 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
2.6 7.7 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
2.5 30.4 GO:0006265 DNA topological change(GO:0006265)
2.5 10.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
2.5 7.5 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
2.4 9.8 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
2.4 53.3 GO:0006376 mRNA splice site selection(GO:0006376)
2.4 38.7 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
2.4 7.2 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
2.4 14.3 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
2.4 23.7 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
2.4 9.5 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
2.4 16.6 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
2.4 7.1 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
2.3 16.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
2.3 9.3 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
2.3 11.5 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
2.3 16.1 GO:0003360 brainstem development(GO:0003360)
2.3 13.7 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
2.3 13.7 GO:1903753 negative regulation of p38MAPK cascade(GO:1903753)
2.3 11.4 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
2.3 11.4 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
2.3 15.8 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
2.2 6.7 GO:0061198 fungiform papilla formation(GO:0061198)
2.2 8.9 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
2.2 6.6 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
2.2 6.6 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
2.2 6.6 GO:0032916 positive regulation of transforming growth factor beta3 production(GO:0032916)
2.2 34.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
2.2 4.3 GO:0034729 histone H3-K79 methylation(GO:0034729)
2.2 25.8 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
2.1 8.6 GO:0043504 mitochondrial DNA repair(GO:0043504)
2.1 23.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
2.1 36.1 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
2.1 8.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
2.0 12.3 GO:1904354 negative regulation of telomere capping(GO:1904354)
2.0 4.1 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
2.0 16.2 GO:0071233 cellular response to leucine(GO:0071233)
2.0 6.0 GO:0071934 thiamine transmembrane transport(GO:0071934)
2.0 8.0 GO:0072709 cellular response to sorbitol(GO:0072709)
2.0 6.0 GO:0034418 urate biosynthetic process(GO:0034418)
2.0 13.7 GO:0018202 peptidyl-histidine modification(GO:0018202)
1.9 5.8 GO:1903972 regulation of interleukin-6-mediated signaling pathway(GO:0070103) regulation of prolactin signaling pathway(GO:1902211) regulation of interleukin-4-mediated signaling pathway(GO:1902214) regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
1.9 7.6 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
1.9 5.6 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
1.9 58.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
1.9 5.6 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
1.9 11.1 GO:1904587 response to glycoprotein(GO:1904587)
1.8 9.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
1.8 11.1 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
1.8 20.2 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
1.8 11.0 GO:0015074 DNA integration(GO:0015074)
1.8 3.6 GO:1990839 response to endothelin(GO:1990839) cellular response to endothelin(GO:1990859)
1.8 5.5 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
1.8 10.9 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
1.8 5.4 GO:0090169 regulation of spindle assembly(GO:0090169) regulation of mitotic spindle assembly(GO:1901673)
1.8 10.6 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
1.8 5.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
1.8 7.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
1.8 43.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
1.7 3.5 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
1.7 15.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
1.7 26.4 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
1.6 19.8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.6 6.6 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
1.6 11.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.6 4.8 GO:0048254 snoRNA localization(GO:0048254)
1.6 8.0 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
1.6 7.9 GO:0016259 selenocysteine metabolic process(GO:0016259)
1.6 19.0 GO:1990403 embryonic brain development(GO:1990403)
1.6 4.8 GO:0016584 nucleosome positioning(GO:0016584)
1.6 11.0 GO:0051661 maintenance of centrosome location(GO:0051661)
1.6 14.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
1.6 37.3 GO:0060712 spongiotrophoblast layer development(GO:0060712)
1.5 13.7 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
1.5 9.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
1.5 16.6 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
1.5 4.5 GO:0016598 protein arginylation(GO:0016598)
1.5 9.0 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
1.5 17.9 GO:0031498 chromatin disassembly(GO:0031498)
1.5 2.9 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
1.5 17.5 GO:0071481 cellular response to X-ray(GO:0071481)
1.5 7.3 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
1.5 7.3 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
1.4 36.9 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
1.4 11.3 GO:0007021 tubulin complex assembly(GO:0007021)
1.4 7.1 GO:0033523 histone H2B ubiquitination(GO:0033523)
1.4 11.2 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
1.4 8.4 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
1.4 11.1 GO:0097327 response to antineoplastic agent(GO:0097327)
1.3 18.7 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
1.3 5.4 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
1.3 6.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
1.3 17.1 GO:0000245 spliceosomal complex assembly(GO:0000245)
1.3 3.9 GO:0030576 Cajal body organization(GO:0030576)
1.2 10.0 GO:0007020 microtubule nucleation(GO:0007020)
1.2 13.7 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
1.2 13.5 GO:0031167 rRNA methylation(GO:0031167)
1.2 8.6 GO:0009838 abscission(GO:0009838)
1.2 1.2 GO:0006408 snRNA export from nucleus(GO:0006408)
1.2 4.9 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
1.2 19.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
1.2 42.1 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
1.2 3.6 GO:0006501 C-terminal protein lipidation(GO:0006501)
1.2 2.4 GO:0021698 cerebellar cortex structural organization(GO:0021698)
1.2 15.1 GO:0050684 regulation of mRNA processing(GO:0050684)
1.2 13.8 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
1.2 5.8 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
1.2 2.3 GO:1905214 regulation of mRNA binding(GO:1902415) regulation of RNA binding(GO:1905214)
1.1 10.3 GO:0042635 positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
1.1 3.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
1.1 3.4 GO:0034499 late endosome to Golgi transport(GO:0034499)
1.1 7.9 GO:0019985 translesion synthesis(GO:0019985)
1.1 11.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
1.1 11.0 GO:0048739 cardiac muscle fiber development(GO:0048739)
1.1 3.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
1.1 3.2 GO:1901227 negative regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901227)
1.1 11.6 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
1.1 4.2 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
1.1 15.8 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
1.0 9.4 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
1.0 4.2 GO:0070370 cellular heat acclimation(GO:0070370)
1.0 4.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
1.0 3.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
1.0 26.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
1.0 4.2 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
1.0 4.2 GO:0018992 germ-line sex determination(GO:0018992)
1.0 7.2 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
1.0 7.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
1.0 8.1 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
1.0 13.1 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
1.0 7.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
1.0 12.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
1.0 4.0 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
1.0 13.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
1.0 45.9 GO:1903146 regulation of mitophagy(GO:1903146)
1.0 32.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
1.0 22.8 GO:0034453 microtubule anchoring(GO:0034453)
1.0 14.7 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
1.0 2.0 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
1.0 18.5 GO:0007080 mitotic metaphase plate congression(GO:0007080)
1.0 3.9 GO:0090204 protein localization to nuclear pore(GO:0090204)
1.0 3.8 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.9 15.8 GO:0035493 SNARE complex assembly(GO:0035493)
0.9 5.6 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.9 19.4 GO:0031050 dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918)
0.9 12.0 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.9 13.7 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.9 6.4 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.9 9.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.9 8.1 GO:2000197 regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
0.9 17.5 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.9 6.9 GO:0070914 UV-damage excision repair(GO:0070914)
0.9 6.8 GO:0051182 coenzyme transport(GO:0051182)
0.9 5.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.9 20.4 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.8 3.4 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.8 2.5 GO:0043179 rhythmic excitation(GO:0043179)
0.8 14.0 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.8 10.7 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.8 33.6 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.8 46.3 GO:0006414 translational elongation(GO:0006414)
0.8 8.9 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.8 12.1 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.8 42.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.8 14.5 GO:0016578 histone deubiquitination(GO:0016578)
0.8 7.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.8 23.8 GO:0042119 neutrophil activation(GO:0042119)
0.8 19.8 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.8 10.3 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.8 48.4 GO:0070228 regulation of lymphocyte apoptotic process(GO:0070228)
0.8 3.2 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.8 17.9 GO:0048243 norepinephrine secretion(GO:0048243)
0.8 10.1 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.8 6.1 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.8 2.3 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984)
0.8 16.0 GO:0034508 centromere complex assembly(GO:0034508)
0.8 3.8 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.8 4.5 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.7 30.8 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.7 0.7 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.7 2.9 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
0.7 8.6 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.7 4.3 GO:0060017 parathyroid gland development(GO:0060017)
0.7 2.9 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.7 2.8 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.7 4.9 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.7 11.9 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.7 8.4 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.7 2.8 GO:0060768 epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.7 6.3 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.7 15.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.7 2.1 GO:0071298 cellular response to L-ascorbic acid(GO:0071298)
0.7 12.5 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.7 13.2 GO:0044247 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.7 1.4 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.7 23.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.7 4.7 GO:0090267 positive regulation of spindle checkpoint(GO:0090232) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.7 8.0 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.7 2.0 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.7 4.7 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.7 3.3 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.7 2.0 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.6 3.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.6 26.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.6 9.6 GO:0060746 parental behavior(GO:0060746)
0.6 8.3 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.6 1.9 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.6 5.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.6 3.8 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.6 10.5 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.6 12.4 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.6 6.8 GO:0006379 mRNA cleavage(GO:0006379)
0.6 1.9 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.6 4.3 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.6 2.5 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.6 1.8 GO:0015960 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.6 133.1 GO:0008380 RNA splicing(GO:0008380)
0.6 3.6 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.6 19.3 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.6 18.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.6 18.0 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.6 4.0 GO:0006598 polyamine catabolic process(GO:0006598)
0.6 3.4 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.6 4.0 GO:0006824 cobalt ion transport(GO:0006824)
0.6 16.0 GO:0006817 phosphate ion transport(GO:0006817)
0.5 9.3 GO:0006907 pinocytosis(GO:0006907)
0.5 1.6 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.5 5.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.5 4.3 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.5 2.1 GO:0048318 axial mesoderm development(GO:0048318)
0.5 2.1 GO:0043418 homocysteine catabolic process(GO:0043418)
0.5 7.8 GO:0070166 enamel mineralization(GO:0070166)
0.5 6.7 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.5 2.6 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.5 21.4 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.5 10.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.5 5.6 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.5 5.0 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.5 12.4 GO:0032873 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.5 8.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.5 4.9 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.5 1.5 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.5 18.8 GO:0060976 coronary vasculature development(GO:0060976)
0.5 7.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.5 6.6 GO:0001522 pseudouridine synthesis(GO:0001522)
0.5 14.1 GO:0001510 RNA methylation(GO:0001510)
0.5 1.8 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.5 22.2 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.5 21.3 GO:0008033 tRNA processing(GO:0008033)
0.4 3.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.4 16.0 GO:0010761 fibroblast migration(GO:0010761)
0.4 2.1 GO:0001582 detection of chemical stimulus involved in sensory perception of sweet taste(GO:0001582)
0.4 3.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.4 2.6 GO:0007000 nucleolus organization(GO:0007000)
0.4 11.9 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.4 10.6 GO:0048266 behavioral response to pain(GO:0048266)
0.4 5.9 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.4 4.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.4 5.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.4 0.8 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.4 2.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.4 13.3 GO:0032543 mitochondrial translation(GO:0032543)
0.4 3.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.4 3.6 GO:0045116 protein neddylation(GO:0045116)
0.4 6.4 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.4 15.9 GO:0007520 myoblast fusion(GO:0007520)
0.4 1.6 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.4 2.4 GO:1904424 regulation of GTP binding(GO:1904424)
0.4 0.8 GO:0032258 CVT pathway(GO:0032258)
0.4 4.7 GO:0050995 negative regulation of lipid catabolic process(GO:0050995) regulation of type B pancreatic cell proliferation(GO:0061469)
0.4 2.0 GO:0010869 regulation of receptor biosynthetic process(GO:0010869)
0.4 8.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.4 5.6 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.4 4.8 GO:0035994 response to muscle stretch(GO:0035994)
0.4 2.2 GO:2000641 regulation of early endosome to late endosome transport(GO:2000641)
0.4 4.4 GO:0031577 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic sister chromatid segregation(GO:0033048) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174) negative regulation of mitotic sister chromatid separation(GO:2000816)
0.4 5.4 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.4 7.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.4 3.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.4 17.1 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.4 4.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.4 10.2 GO:0006270 DNA replication initiation(GO:0006270)
0.3 1.0 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.3 7.3 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.3 13.9 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.3 3.4 GO:0048820 hair follicle maturation(GO:0048820)
0.3 24.8 GO:0034470 ncRNA processing(GO:0034470)
0.3 7.6 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.3 3.0 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.3 9.2 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.3 2.3 GO:0006465 signal peptide processing(GO:0006465)
0.3 4.9 GO:0008340 determination of adult lifespan(GO:0008340)
0.3 2.9 GO:0018344 protein geranylgeranylation(GO:0018344)
0.3 2.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.3 3.5 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.3 2.0 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.3 2.3 GO:0060177 regulation of angiotensin levels in blood(GO:0002002) regulation of angiotensin metabolic process(GO:0060177)
0.3 16.6 GO:0048661 positive regulation of smooth muscle cell proliferation(GO:0048661)
0.3 3.5 GO:0009060 aerobic respiration(GO:0009060)
0.3 6.5 GO:0030330 DNA damage response, signal transduction by p53 class mediator(GO:0030330)
0.3 12.9 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.3 2.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.3 97.6 GO:0006412 translation(GO:0006412)
0.3 1.8 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.3 2.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.3 2.0 GO:0030220 platelet formation(GO:0030220)
0.2 5.9 GO:0003016 respiratory system process(GO:0003016)
0.2 1.0 GO:0021633 optic nerve structural organization(GO:0021633)
0.2 1.7 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.2 1.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.2 0.7 GO:0072553 terminal button organization(GO:0072553)
0.2 10.2 GO:0006338 chromatin remodeling(GO:0006338)
0.2 6.6 GO:1901099 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.2 11.3 GO:0006396 RNA processing(GO:0006396)
0.2 4.3 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.2 20.8 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.2 0.7 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.2 0.5 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.2 1.6 GO:0031648 protein destabilization(GO:0031648)
0.2 6.9 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.2 4.6 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.2 12.3 GO:0000209 protein polyubiquitination(GO:0000209)
0.2 2.0 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.2 3.3 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.2 1.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.2 2.7 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.2 1.3 GO:0002076 osteoblast development(GO:0002076)
0.2 17.7 GO:0008360 regulation of cell shape(GO:0008360)
0.2 3.3 GO:0060416 response to growth hormone(GO:0060416)
0.2 7.4 GO:0000819 sister chromatid segregation(GO:0000819)
0.2 5.7 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.2 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 7.6 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.1 1.0 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 12.6 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.1 4.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.4 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.1 0.8 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 4.2 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.1 2.5 GO:0060325 face morphogenesis(GO:0060325)
0.1 1.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 2.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 3.2 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.1 3.7 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.1 9.7 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.1 1.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 10.3 GO:0051291 protein heterooligomerization(GO:0051291)
0.1 2.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 0.3 GO:0046755 viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.1 1.3 GO:0001502 cartilage condensation(GO:0001502)
0.1 3.5 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.1 1.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 1.9 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.9 GO:0006517 protein deglycosylation(GO:0006517)
0.1 3.7 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 5.1 GO:0007030 Golgi organization(GO:0007030)
0.1 3.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 1.7 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 1.6 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.1 2.4 GO:0014902 myotube differentiation(GO:0014902)
0.1 5.8 GO:0070372 regulation of ERK1 and ERK2 cascade(GO:0070372)
0.1 0.2 GO:0035627 ceramide transport(GO:0035627)
0.0 0.9 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.1 GO:0043247 telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.3 GO:0046836 glycolipid transport(GO:0046836)
0.0 1.0 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.3 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.6 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.4 GO:2000648 positive regulation of stem cell proliferation(GO:2000648)
0.0 1.1 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 0.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.6 GO:0051384 response to glucocorticoid(GO:0051384)
0.0 0.3 GO:0071277 cellular response to calcium ion(GO:0071277)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
11.5 91.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
10.1 10.1 GO:0070069 cytochrome complex(GO:0070069)
8.6 25.8 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
7.0 20.9 GO:0005962 mitochondrial isocitrate dehydrogenase complex (NAD+)(GO:0005962) isocitrate dehydrogenase complex (NAD+)(GO:0045242)
5.7 17.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
5.7 17.0 GO:0035577 azurophil granule membrane(GO:0035577) tertiary granule membrane(GO:0070821)
5.5 22.2 GO:0045273 respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281)
5.3 21.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
5.3 26.7 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
5.0 40.2 GO:0097452 GAIT complex(GO:0097452)
4.9 14.8 GO:0032301 MutSalpha complex(GO:0032301)
4.8 38.3 GO:0000796 condensin complex(GO:0000796)
4.8 19.0 GO:0032021 NELF complex(GO:0032021)
4.7 14.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
4.6 18.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
4.6 13.7 GO:0008275 gamma-tubulin small complex(GO:0008275)
4.2 38.0 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
4.1 16.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
3.9 11.6 GO:1990826 nucleoplasmic periphery of the nuclear pore complex(GO:1990826)
3.7 25.9 GO:0042382 paraspeckles(GO:0042382)
3.6 17.9 GO:0035061 interchromatin granule(GO:0035061)
3.5 17.7 GO:0097165 nuclear stress granule(GO:0097165)
3.4 10.3 GO:0044611 nuclear pore inner ring(GO:0044611)
3.3 16.6 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
3.2 35.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
3.1 30.5 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
3.0 3.0 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
3.0 15.0 GO:0044530 supraspliceosomal complex(GO:0044530)
3.0 23.6 GO:0005638 lamin filament(GO:0005638)
2.9 11.7 GO:0000444 MIS12/MIND type complex(GO:0000444)
2.9 20.5 GO:0005683 U7 snRNP(GO:0005683)
2.9 23.1 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
2.9 11.5 GO:0044307 dendritic branch(GO:0044307)
2.9 14.3 GO:0070820 tertiary granule(GO:0070820)
2.8 36.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
2.8 11.0 GO:0036398 TCR signalosome(GO:0036398)
2.6 15.4 GO:0089701 U2AF(GO:0089701)
2.6 2.6 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
2.5 12.5 GO:0072557 IPAF inflammasome complex(GO:0072557)
2.3 11.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
2.3 27.6 GO:0071004 U2-type prespliceosome(GO:0071004)
2.3 6.8 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
2.3 15.8 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
2.2 20.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
2.2 17.7 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
2.2 28.0 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
2.1 12.9 GO:0097422 tubular endosome(GO:0097422)
2.1 14.9 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
2.1 10.5 GO:1990462 omegasome membrane(GO:1903349) omegasome(GO:1990462)
2.1 35.7 GO:0000346 transcription export complex(GO:0000346)
2.1 50.3 GO:0035145 exon-exon junction complex(GO:0035145)
2.1 24.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
1.9 37.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
1.9 11.3 GO:0042788 polysomal ribosome(GO:0042788)
1.8 22.0 GO:0005684 U2-type spliceosomal complex(GO:0005684)
1.8 5.5 GO:0070557 PCNA-p21 complex(GO:0070557)
1.8 14.5 GO:0001740 Barr body(GO:0001740)
1.8 21.3 GO:0071564 npBAF complex(GO:0071564)
1.8 10.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
1.8 7.0 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
1.7 8.6 GO:0098536 deuterosome(GO:0098536)
1.7 8.5 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
1.6 21.0 GO:0005885 Arp2/3 protein complex(GO:0005885)
1.6 24.2 GO:0016580 Sin3 complex(GO:0016580)
1.6 18.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
1.5 13.8 GO:0031010 ISWI-type complex(GO:0031010)
1.5 12.1 GO:0000798 nuclear cohesin complex(GO:0000798)
1.5 37.6 GO:0000242 pericentriolar material(GO:0000242)
1.5 9.0 GO:0001652 granular component(GO:0001652)
1.5 26.7 GO:0005849 mRNA cleavage factor complex(GO:0005849)
1.5 41.1 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
1.5 39.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
1.4 17.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
1.4 24.1 GO:0071011 precatalytic spliceosome(GO:0071011)
1.4 41.1 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
1.4 8.5 GO:0030289 protein phosphatase 4 complex(GO:0030289)
1.4 133.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
1.4 5.5 GO:0031417 NatC complex(GO:0031417)
1.4 22.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
1.4 5.4 GO:0043259 laminin-10 complex(GO:0043259)
1.4 6.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
1.4 16.3 GO:0005859 muscle myosin complex(GO:0005859)
1.3 269.7 GO:0005840 ribosome(GO:0005840)
1.3 6.7 GO:0070552 BRISC complex(GO:0070552)
1.3 9.4 GO:0031415 NatA complex(GO:0031415)
1.3 10.7 GO:0016272 prefoldin complex(GO:0016272)
1.3 7.9 GO:1990246 uniplex complex(GO:1990246)
1.3 17.0 GO:0008385 IkappaB kinase complex(GO:0008385)
1.3 14.3 GO:0042555 MCM complex(GO:0042555)
1.3 9.1 GO:0090543 Flemming body(GO:0090543)
1.3 5.1 GO:0033553 rDNA heterochromatin(GO:0033553)
1.2 4.9 GO:0097427 microtubule bundle(GO:0097427)
1.2 4.8 GO:0031428 box C/D snoRNP complex(GO:0031428) pre-snoRNP complex(GO:0070761)
1.2 23.8 GO:0005680 anaphase-promoting complex(GO:0005680)
1.2 12.9 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
1.2 5.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
1.1 9.0 GO:0031931 TORC1 complex(GO:0031931)
1.1 19.4 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287)
1.0 5.2 GO:0044327 dendritic spine head(GO:0044327)
1.0 20.4 GO:0001891 phagocytic cup(GO:0001891)
1.0 4.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
1.0 2.9 GO:0090534 longitudinal sarcoplasmic reticulum(GO:0014801) calcium ion-transporting ATPase complex(GO:0090534)
1.0 7.8 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.9 18.9 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.9 5.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.9 3.7 GO:0033503 HULC complex(GO:0033503)
0.9 16.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.9 30.6 GO:0000791 euchromatin(GO:0000791)
0.9 3.6 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.9 20.5 GO:0032040 small-subunit processome(GO:0032040)
0.9 7.1 GO:0032584 growth cone membrane(GO:0032584)
0.9 4.4 GO:0005682 U5 snRNP(GO:0005682)
0.9 5.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.9 15.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.9 2.6 GO:0072487 MSL complex(GO:0072487)
0.8 4.2 GO:0031933 telomeric heterochromatin(GO:0031933)
0.8 4.2 GO:0034455 t-UTP complex(GO:0034455)
0.8 10.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.8 12.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.8 10.5 GO:0000178 exosome (RNase complex)(GO:0000178)
0.8 40.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.8 8.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.8 3.2 GO:0070545 PeBoW complex(GO:0070545)
0.8 7.1 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.8 5.4 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.8 9.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.8 8.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.7 8.0 GO:0097431 mitotic spindle pole(GO:0097431)
0.7 7.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.7 11.5 GO:0019013 viral nucleocapsid(GO:0019013)
0.7 3.6 GO:0071203 WASH complex(GO:0071203)
0.7 4.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.7 7.1 GO:0070187 telosome(GO:0070187)
0.7 31.6 GO:0016592 mediator complex(GO:0016592)
0.7 4.9 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.7 16.8 GO:0005839 proteasome core complex(GO:0005839)
0.7 57.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.7 17.7 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.7 2.0 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.7 11.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.7 11.3 GO:0032039 integrator complex(GO:0032039)
0.7 8.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.7 62.7 GO:0005681 spliceosomal complex(GO:0005681)
0.6 6.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.6 4.3 GO:0097346 INO80-type complex(GO:0097346)
0.6 12.4 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.6 2.9 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.6 3.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.6 6.6 GO:0030008 TRAPP complex(GO:0030008)
0.5 4.4 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.5 13.1 GO:0034451 centriolar satellite(GO:0034451)
0.5 4.8 GO:0000813 ESCRT I complex(GO:0000813)
0.5 3.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.5 22.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.5 5.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.5 9.9 GO:0030057 desmosome(GO:0030057)
0.5 5.0 GO:0035102 PRC1 complex(GO:0035102)
0.4 123.5 GO:0016607 nuclear speck(GO:0016607)
0.4 60.2 GO:0000793 condensed chromosome(GO:0000793)
0.4 2.1 GO:1903768 sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
0.4 3.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.4 2.1 GO:0071953 elastic fiber(GO:0071953)
0.4 1.3 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.4 10.0 GO:0035097 histone methyltransferase complex(GO:0035097)
0.4 3.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.4 3.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.4 18.8 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.4 5.1 GO:0015030 Cajal body(GO:0015030)
0.4 2.3 GO:0005787 signal peptidase complex(GO:0005787)
0.4 22.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.4 4.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.4 1.8 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.4 7.9 GO:0035371 microtubule plus-end(GO:0035371)
0.4 2.2 GO:0036128 CatSper complex(GO:0036128)
0.3 4.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.3 14.4 GO:0000776 kinetochore(GO:0000776)
0.3 3.3 GO:0051286 cell tip(GO:0051286)
0.3 1.3 GO:0035976 AP1 complex(GO:0035976)
0.3 11.7 GO:0031672 A band(GO:0031672)
0.3 20.6 GO:0016605 PML body(GO:0016605)
0.3 13.2 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.3 18.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.3 1.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3 19.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.3 7.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 8.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.3 3.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.3 77.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.3 21.1 GO:0005776 autophagosome(GO:0005776)
0.3 19.4 GO:0005694 chromosome(GO:0005694)
0.3 26.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.3 1.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.2 1.0 GO:0035253 ciliary rootlet(GO:0035253)
0.2 22.4 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.2 3.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 2.4 GO:0070938 contractile ring(GO:0070938)
0.2 2.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 27.2 GO:0032993 protein-DNA complex(GO:0032993)
0.2 6.1 GO:0035869 ciliary transition zone(GO:0035869)
0.2 1.9 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.2 1.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 1.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.2 0.8 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 4.8 GO:0016235 aggresome(GO:0016235)
0.2 3.8 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.2 3.0 GO:1990391 DNA repair complex(GO:1990391)
0.1 3.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 21.4 GO:0000790 nuclear chromatin(GO:0000790)
0.1 160.2 GO:0005739 mitochondrion(GO:0005739)
0.1 1.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 5.8 GO:0005871 kinesin complex(GO:0005871)
0.1 5.6 GO:0016459 myosin complex(GO:0016459)
0.1 3.4 GO:0008180 COP9 signalosome(GO:0008180)
0.1 6.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 64.0 GO:0005730 nucleolus(GO:0005730)
0.1 2.8 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 0.6 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.6 GO:0032797 SMN complex(GO:0032797)
0.1 0.4 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 1.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 8.0 GO:0005923 bicellular tight junction(GO:0005923)
0.1 10.7 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 0.8 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 58.2 GO:0005654 nucleoplasm(GO:0005654)
0.1 1.8 GO:0005811 lipid particle(GO:0005811)
0.0 13.9 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.5 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.6 GO:0043292 contractile fiber(GO:0043292)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 3.4 GO:0031012 extracellular matrix(GO:0031012)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.5 22.4 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
6.7 20.2 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
6.4 31.9 GO:0050733 RS domain binding(GO:0050733)
6.2 24.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
6.0 18.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
5.6 22.4 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
5.6 16.7 GO:0000104 succinate dehydrogenase activity(GO:0000104)
5.5 21.9 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
5.2 20.9 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
5.1 20.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
4.9 78.1 GO:0008143 poly(A) binding(GO:0008143)
4.7 14.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
4.6 13.8 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
4.4 13.3 GO:0030626 U12 snRNA binding(GO:0030626)
4.4 13.2 GO:0008184 glycogen phosphorylase activity(GO:0008184)
4.4 13.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
4.3 17.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
4.2 12.7 GO:0097677 STAT family protein binding(GO:0097677)
4.1 12.3 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
4.0 12.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
3.9 11.6 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
3.9 7.7 GO:0045322 unmethylated CpG binding(GO:0045322)
3.6 21.6 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
3.6 21.4 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
3.6 14.2 GO:1904288 BAT3 complex binding(GO:1904288)
3.5 10.6 GO:0016509 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
3.5 10.6 GO:0034057 RNA strand-exchange activity(GO:0034057)
3.4 30.4 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
3.3 9.9 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
3.3 9.8 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
3.1 9.3 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
3.0 18.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
3.0 11.9 GO:0004594 pantothenate kinase activity(GO:0004594)
2.9 8.6 GO:0052723 inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
2.8 24.9 GO:0043024 ribosomal small subunit binding(GO:0043024)
2.8 24.9 GO:0001054 RNA polymerase I activity(GO:0001054)
2.7 13.7 GO:0050816 phosphothreonine binding(GO:0050816)
2.6 34.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
2.6 23.6 GO:0015266 protein channel activity(GO:0015266)
2.6 7.8 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
2.6 15.6 GO:0071532 ankyrin repeat binding(GO:0071532)
2.6 7.7 GO:0032551 UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
2.5 7.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
2.3 51.4 GO:0003746 translation elongation factor activity(GO:0003746)
2.3 13.9 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
2.2 6.7 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
2.2 44.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
2.2 8.9 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
2.2 6.6 GO:1990763 arrestin family protein binding(GO:1990763)
2.2 6.6 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
2.2 8.7 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
2.1 8.4 GO:0050682 AF-2 domain binding(GO:0050682)
2.1 14.5 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
2.0 12.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
2.0 6.0 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
2.0 16.0 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
2.0 5.9 GO:0033592 RNA strand annealing activity(GO:0033592)
1.9 19.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
1.9 7.6 GO:0016842 amidine-lyase activity(GO:0016842)
1.9 13.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.9 9.3 GO:0036033 mediator complex binding(GO:0036033)
1.8 7.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
1.8 19.7 GO:0032036 myosin heavy chain binding(GO:0032036)
1.8 10.7 GO:0070728 leucine binding(GO:0070728)
1.8 10.6 GO:0003923 GPI-anchor transamidase activity(GO:0003923) GPI anchor binding(GO:0034235)
1.8 7.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
1.7 24.0 GO:0003688 DNA replication origin binding(GO:0003688)
1.7 10.3 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
1.7 21.6 GO:0050321 tau-protein kinase activity(GO:0050321)
1.6 13.1 GO:0034452 dynactin binding(GO:0034452)
1.6 21.3 GO:1990405 protein antigen binding(GO:1990405)
1.6 6.5 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
1.6 41.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
1.6 16.0 GO:0016929 SUMO-specific protease activity(GO:0016929)
1.6 4.8 GO:0102390 mycophenolic acid acyl-glucuronide esterase activity(GO:0102390)
1.6 12.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
1.6 6.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.5 23.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
1.5 9.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
1.5 9.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
1.5 19.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
1.5 20.8 GO:0017091 AU-rich element binding(GO:0017091)
1.5 10.4 GO:0017070 U6 snRNA binding(GO:0017070)
1.4 5.7 GO:0030283 testosterone dehydrogenase [NAD(P)] activity(GO:0030283)
1.4 25.5 GO:0044548 S100 protein binding(GO:0044548)
1.4 5.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
1.4 5.5 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
1.4 6.8 GO:0051185 coenzyme transporter activity(GO:0051185)
1.3 6.7 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
1.3 10.7 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
1.3 8.0 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
1.3 350.9 GO:0003735 structural constituent of ribosome(GO:0003735)
1.3 11.9 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
1.3 9.2 GO:0031685 adenosine receptor binding(GO:0031685)
1.3 10.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
1.3 10.0 GO:0070513 death domain binding(GO:0070513)
1.2 13.7 GO:0051011 microtubule minus-end binding(GO:0051011)
1.2 6.2 GO:0035497 cAMP response element binding(GO:0035497)
1.2 34.1 GO:0003954 NADH dehydrogenase activity(GO:0003954)
1.2 4.9 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
1.2 26.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
1.2 7.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
1.2 4.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
1.2 17.5 GO:0070182 DNA polymerase binding(GO:0070182)
1.2 45.3 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
1.2 5.8 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
1.1 16.0 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
1.1 3.4 GO:0031770 growth hormone-releasing hormone receptor binding(GO:0031770)
1.1 4.5 GO:0099609 microtubule lateral binding(GO:0099609)
1.1 25.8 GO:0043274 phospholipase binding(GO:0043274)
1.1 15.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
1.1 6.6 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
1.1 7.7 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
1.1 21.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
1.1 6.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
1.1 8.6 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
1.1 5.3 GO:0070717 poly-purine tract binding(GO:0070717)
1.1 14.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
1.1 29.5 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
1.1 8.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.0 13.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.0 11.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
1.0 4.0 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
1.0 14.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
1.0 4.0 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
1.0 7.8 GO:0008312 7S RNA binding(GO:0008312)
1.0 4.8 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
1.0 4.8 GO:0030348 syntaxin-3 binding(GO:0030348)
0.9 11.4 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.9 22.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.9 12.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.9 13.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.9 5.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.9 20.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.9 3.6 GO:0019776 Atg8 ligase activity(GO:0019776)
0.9 32.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.9 13.1 GO:0043422 protein kinase B binding(GO:0043422)
0.9 5.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.9 15.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.9 2.6 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.8 16.0 GO:0046965 retinoid X receptor binding(GO:0046965)
0.8 24.9 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.8 15.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.8 8.9 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.8 4.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.8 11.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.8 2.3 GO:0030350 iron-responsive element binding(GO:0030350)
0.8 17.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.8 10.6 GO:0048156 tau protein binding(GO:0048156)
0.8 10.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.7 11.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.7 15.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.7 2.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.7 2.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.7 3.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.7 2.1 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.7 2.8 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.7 4.8 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.7 6.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.7 4.7 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.7 36.9 GO:0035064 methylated histone binding(GO:0035064)
0.7 3.3 GO:0030911 TPR domain binding(GO:0030911)
0.7 35.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.6 3.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.6 110.9 GO:0001047 core promoter binding(GO:0001047)
0.6 16.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.6 5.5 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.6 10.9 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.6 3.6 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.6 13.1 GO:0015288 porin activity(GO:0015288)
0.6 13.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.6 2.4 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.6 24.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.6 11.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.6 4.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.6 1.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.6 5.0 GO:0004659 prenyltransferase activity(GO:0004659)
0.5 6.0 GO:0016208 AMP binding(GO:0016208)
0.5 2.7 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.5 16.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.5 28.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.5 12.7 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.5 9.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.5 4.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.5 4.4 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.5 5.7 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.5 5.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.5 1.4 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.4 5.7 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.4 2.1 GO:0033041 sweet taste receptor activity(GO:0033041)
0.4 11.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.4 4.7 GO:0005000 vasopressin receptor activity(GO:0005000)
0.4 7.1 GO:0017160 Ral GTPase binding(GO:0017160)
0.4 1.6 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.4 3.3 GO:0009881 photoreceptor activity(GO:0009881)
0.4 24.6 GO:0019208 phosphatase regulator activity(GO:0019208)
0.4 7.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.4 10.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.4 14.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.4 11.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.4 2.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.4 4.1 GO:0070410 co-SMAD binding(GO:0070410)
0.4 3.3 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.4 26.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.4 2.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.4 31.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.4 9.0 GO:0043531 ADP binding(GO:0043531)
0.4 84.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.3 18.2 GO:0003682 chromatin binding(GO:0003682)
0.3 19.9 GO:0047485 protein N-terminus binding(GO:0047485)
0.3 11.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.3 7.6 GO:0030331 estrogen receptor binding(GO:0030331)
0.3 19.8 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.3 7.4 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.3 6.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.3 17.3 GO:0042393 histone binding(GO:0042393)
0.3 7.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.3 1.6 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.3 1.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.3 3.6 GO:0070034 telomerase RNA binding(GO:0070034)
0.3 4.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.3 6.9 GO:0008198 ferrous iron binding(GO:0008198)
0.3 327.7 GO:0003723 RNA binding(GO:0003723)
0.3 11.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.3 15.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.3 4.9 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.3 4.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.3 2.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.3 1.5 GO:0050681 androgen receptor binding(GO:0050681)
0.2 7.4 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.2 4.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 1.9 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.2 8.1 GO:0042605 peptide antigen binding(GO:0042605)
0.2 4.8 GO:0043022 ribosome binding(GO:0043022)
0.2 8.7 GO:0042169 SH2 domain binding(GO:0042169)
0.2 97.5 GO:0046982 protein heterodimerization activity(GO:0046982)
0.2 1.6 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 11.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 1.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 16.2 GO:0003777 microtubule motor activity(GO:0003777)
0.2 0.8 GO:0042731 PH domain binding(GO:0042731)
0.2 1.6 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.2 4.6 GO:0002039 p53 binding(GO:0002039)
0.2 4.3 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.2 4.5 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.2 6.9 GO:0051540 iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.2 6.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 16.2 GO:0005178 integrin binding(GO:0005178)
0.2 2.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 10.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 1.7 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 12.0 GO:0019903 protein phosphatase binding(GO:0019903)
0.1 2.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 2.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 4.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 5.5 GO:0032947 protein complex scaffold(GO:0032947)
0.1 1.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 12.4 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.1 13.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.0 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 0.3 GO:0015292 uniporter activity(GO:0015292)
0.1 0.5 GO:0000182 rDNA binding(GO:0000182)
0.1 13.9 GO:0020037 heme binding(GO:0020037)
0.1 7.4 GO:0044325 ion channel binding(GO:0044325)
0.1 6.9 GO:0008168 methyltransferase activity(GO:0008168)
0.1 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 2.1 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.1 3.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 5.1 GO:0016853 isomerase activity(GO:0016853)
0.1 0.9 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 0.8 GO:0070840 dynein complex binding(GO:0070840)
0.1 1.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 3.8 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 23.8 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 5.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 9.4 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 32.4 GO:0003676 nucleic acid binding(GO:0003676)
0.0 0.1 GO:0004040 amidase activity(GO:0004040) glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.2 GO:0097001 ceramide binding(GO:0097001)
0.0 3.5 GO:0005125 cytokine activity(GO:0005125)
0.0 0.2 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 4.1 GO:0005198 structural molecule activity(GO:0005198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 98.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
2.0 22.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
1.6 50.0 PID MYC PATHWAY C-MYC pathway
1.6 74.3 PID AURORA B PATHWAY Aurora B signaling
1.5 25.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.4 27.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
1.2 51.8 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
1.1 54.4 PID ILK PATHWAY Integrin-linked kinase signaling
1.0 85.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.9 34.4 SIG CHEMOTAXIS Genes related to chemotaxis
0.8 16.3 PID FAS PATHWAY FAS (CD95) signaling pathway
0.8 19.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.7 37.7 PID E2F PATHWAY E2F transcription factor network
0.7 37.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.7 47.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.7 37.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.7 20.8 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.7 7.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.7 37.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.6 12.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.6 17.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.6 4.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.6 13.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.5 15.7 PID PLK1 PATHWAY PLK1 signaling events
0.5 3.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.5 2.6 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.5 28.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.5 18.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.5 16.0 PID ATM PATHWAY ATM pathway
0.4 5.9 PID AURORA A PATHWAY Aurora A signaling
0.4 21.2 PID P73PATHWAY p73 transcription factor network
0.4 16.8 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.4 5.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 6.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.3 4.7 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.3 5.4 PID ARF 3PATHWAY Arf1 pathway
0.3 7.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.3 7.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 2.4 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.3 7.0 PID ATR PATHWAY ATR signaling pathway
0.3 7.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.3 10.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.2 5.7 PID RAS PATHWAY Regulation of Ras family activation
0.2 5.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.2 4.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 7.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.2 7.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 5.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.2 7.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 9.4 PID CMYB PATHWAY C-MYB transcription factor network
0.2 4.9 PID P53 REGULATION PATHWAY p53 pathway
0.2 3.2 PID AP1 PATHWAY AP-1 transcription factor network
0.2 10.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.2 1.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 3.9 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 2.0 PID IL1 PATHWAY IL1-mediated signaling events
0.1 4.9 PID NOTCH PATHWAY Notch signaling pathway
0.1 2.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 6.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 23.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 2.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 3.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
11.5 91.9 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
3.6 65.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
2.7 10.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
2.3 46.0 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
2.3 47.9 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
2.3 38.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
2.2 111.3 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
2.2 26.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
2.2 26.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
2.1 32.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
2.1 210.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
2.0 32.4 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
1.9 15.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
1.8 49.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
1.8 30.3 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
1.8 15.8 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
1.7 27.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
1.7 3.3 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
1.6 50.1 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
1.6 25.8 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
1.6 25.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
1.6 7.8 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
1.5 27.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
1.5 31.9 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
1.5 25.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
1.5 23.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
1.4 37.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
1.4 16.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.3 18.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
1.3 41.6 REACTOME KINESINS Genes involved in Kinesins
1.3 91.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
1.2 16.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.1 66.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
1.1 21.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.0 7.7 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.9 6.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.9 13.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.9 7.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.9 10.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.9 11.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.9 12.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.9 7.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.9 13.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.9 27.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.8 11.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.8 18.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.8 34.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.8 19.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.8 13.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.7 7.3 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.7 21.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.7 10.7 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.7 13.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.7 10.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.7 10.0 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.6 16.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.6 7.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.6 9.0 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.6 26.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.6 8.5 REACTOME CHROMOSOME MAINTENANCE Genes involved in Chromosome Maintenance
0.6 13.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.6 2.9 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.6 48.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.6 14.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.5 9.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.5 5.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.5 9.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.5 15.4 REACTOME TRANSLATION Genes involved in Translation
0.5 0.5 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.5 15.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.5 10.7 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.5 3.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.4 5.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.4 3.3 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.4 13.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.4 6.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.4 11.0 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.4 14.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.4 20.1 REACTOME MITOTIC G2 G2 M PHASES Genes involved in Mitotic G2-G2/M phases
0.4 2.8 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.3 13.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.3 7.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.3 5.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 2.4 REACTOME OPSINS Genes involved in Opsins
0.3 5.0 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.3 4.3 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.3 8.0 REACTOME MEIOSIS Genes involved in Meiosis
0.3 4.0 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.3 18.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 12.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.3 4.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.2 6.6 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.2 5.8 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.2 3.6 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 5.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 7.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.2 7.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 2.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 3.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 9.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 3.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 2.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 3.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 2.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 0.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 8.8 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.1 15.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 3.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 1.7 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 1.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)