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GSE53960: rat RNA-Seq transcriptomic Bodymap
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Results for Taf1
Z-value: 2.46
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Transcription factors associated with Taf1
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr8_-_49280901 Show fit | 50.57 |
ENSRNOT00000021390
|
CD3g molecule |
|
| chr8_-_49308806 Show fit | 41.30 |
ENSRNOT00000047291
|
CD3e molecule |
|
| chr3_+_112531703 Show fit | 41.28 |
ENSRNOT00000041727
|
protein CASC5-like |
|
| chr2_+_165601007 Show fit | 38.28 |
ENSRNOT00000013931
|
structural maintenance of chromosomes 4 |
|
| chr19_+_37600148 Show fit | 30.65 |
ENSRNOT00000023853
|
CCCTC-binding factor |
|
| chr17_+_9595761 Show fit | 26.04 |
ENSRNOT00000089990
|
family with sequence similarity 193, member B |
|
| chr2_-_123281856 Show fit | 25.78 |
ENSRNOT00000079745
|
cyclin A2 |
|
| chr2_+_53859737 Show fit | 24.75 |
ENSRNOT00000065313
|
3-oxoacid CoA transferase 1 |
|
| chr12_-_30566032 Show fit | 23.30 |
ENSRNOT00000093378
|
glioblastoma amplified sequence |
|
| chr16_-_36080191 Show fit | 22.44 |
ENSRNOT00000017635
|
high mobility group box 2-like 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Taf1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 133.1 | GO:0008380 | RNA splicing(GO:0008380) |
| 0.3 | 97.6 | GO:0006412 | translation(GO:0006412) |
| 1.9 | 58.3 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 2.4 | 53.3 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.8 | 48.4 | GO:0070228 | regulation of lymphocyte apoptotic process(GO:0070228) |
| 0.8 | 46.3 | GO:0006414 | translational elongation(GO:0006414) |
| 1.0 | 45.9 | GO:1903146 | regulation of mitophagy(GO:1903146) |
| 1.8 | 43.8 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.8 | 42.8 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 1.2 | 42.1 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 269.7 | GO:0005840 | ribosome(GO:0005840) |
| 0.1 | 160.2 | GO:0005739 | mitochondrion(GO:0005739) |
| 1.4 | 133.8 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.4 | 123.5 | GO:0016607 | nuclear speck(GO:0016607) |
| 11.5 | 91.9 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.3 | 77.7 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.1 | 64.0 | GO:0005730 | nucleolus(GO:0005730) |
| 0.7 | 62.7 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.4 | 60.2 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.1 | 58.2 | GO:0005654 | nucleoplasm(GO:0005654) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 350.9 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.3 | 327.7 | GO:0003723 | RNA binding(GO:0003723) |
| 0.6 | 110.9 | GO:0001047 | core promoter binding(GO:0001047) |
| 0.2 | 97.5 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
| 0.4 | 84.9 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 4.9 | 78.1 | GO:0008143 | poly(A) binding(GO:0008143) |
| 2.3 | 51.4 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 1.2 | 45.3 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 2.2 | 44.8 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 1.6 | 41.7 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.7 | 98.2 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 1.0 | 85.2 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 1.6 | 74.3 | PID AURORA B PATHWAY | Aurora B signaling |
| 1.1 | 54.4 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 1.2 | 51.8 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 1.6 | 50.0 | PID MYC PATHWAY | C-MYC pathway |
| 0.7 | 47.9 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.7 | 37.7 | PID E2F PATHWAY | E2F transcription factor network |
| 0.7 | 37.6 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.7 | 37.2 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 210.3 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 2.2 | 111.3 | REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION | Genes involved in Cleavage of Growing Transcript in the Termination Region |
| 11.5 | 91.9 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 1.3 | 91.2 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 1.1 | 66.4 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 3.6 | 65.4 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 1.6 | 50.1 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS | Genes involved in CREB phosphorylation through the activation of Ras |
| 1.8 | 49.7 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.6 | 48.0 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 2.3 | 47.9 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |