ISMARA results: T

Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation

Downloads

Results for T

Z-value: 1.20

Motif logo

Transcription factors associated with T

Gene Symbol	Gene ID	Gene Info
T NCBI RGD Ensembl	ENSRNOG00000012229	T brachyury transcription factor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
T	rn6_v1_chr1_-_52894832_52894832	-0.34	7.7e-10	Click!

Activity profile of T motif

Sorted Z-values of T motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr2_-_23289266 Show fit	88.90	ENSRNOT00000061708	Bhmt2 NCBI RGD Ensembl Show fit	betaine-homocysteine S-methyltransferase 2
chr1_+_238222521 Show fit	74.90	ENSRNOT00000024000	Aldh1a1 NCBI RGD Ensembl Show fit	aldehyde dehydrogenase 1 family, member A1
chr20_-_45126062 Show fit	60.65	ENSRNOT00000000720	RGD1310495 NCBI RGD Ensembl Show fit	similar to KIAA1919 protein
chr11_+_74057361 Show fit	48.78	ENSRNOT00000048746	Cpn2 NCBI RGD Ensembl Show fit	carboxypeptidase N subunit 2
chr1_-_240601744 Show fit	48.44	ENSRNOT00000024093	Aldh1a7 NCBI RGD Ensembl Show fit	aldehyde dehydrogenase family 1, subfamily A7
chr2_+_68821004 Show fit	47.81	ENSRNOT00000083713	Egf NCBI RGD Ensembl Show fit	epidermal growth factor
chr1_+_222310920 Show fit	47.43	ENSRNOT00000091465	Macrod1 NCBI RGD Ensembl Show fit	MACRO domain containing 1
chrX_+_110818716 Show fit	42.12	ENSRNOT00000086308	Rnf128 NCBI RGD Ensembl Show fit	ring finger protein 128, E3 ubiquitin protein ligase
chr1_+_148240504 Show fit	42.09	ENSRNOT00000085373	LOC100361547 NCBI RGD Ensembl Show fit	Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chr6_-_127508452 Show fit	38.92	ENSRNOT00000073709	LOC100909524 NCBI RGD Ensembl Show fit	protein Z-dependent protease inhibitor-like

Showing 1 to 10 of 170 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of T

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
11.1	88.9	GO:0043102	amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
9.4	74.9	GO:0042905	optic cup morphogenesis involved in camera-type eye development(GO:0002072) 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
9.7	48.4	GO:0035106	operant conditioning(GO:0035106)
6.0	47.8	GO:0007262	STAT protein import into nucleus(GO:0007262)
11.9	47.4	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
1.6	42.1	GO:0019373	epoxygenase P450 pathway(GO:0019373)
1.5	42.1	GO:0042036	negative regulation of cytokine biosynthetic process(GO:0042036)
5.9	35.3	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.5	33.0	GO:0006953	acute-phase response(GO:0006953)
1.0	28.2	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)

Showing 1 to 10 of 87 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	142.9	GO:0070062	extracellular exosome(GO:0070062)
0.0	88.7	GO:0016021	integral component of membrane(GO:0016021)
0.2	73.1	GO:0005759	mitochondrial matrix(GO:0005759)
0.1	56.2	GO:0005615	extracellular space(GO:0005615)
0.0	43.7	GO:0005739	mitochondrion(GO:0005739)
1.3	37.4	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.2	36.7	GO:0005770	late endosome(GO:0005770)
0.3	33.5	GO:0072562	blood microparticle(GO:0072562)
0.6	26.6	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	25.0	GO:0043235	receptor complex(GO:0043235)

Showing 1 to 10 of 48 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
41.1	123.3	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
11.1	88.9	GO:0008172	S-methyltransferase activity(GO:0008172)
1.2	57.1	GO:0019213	deacetylase activity(GO:0019213)
2.8	47.8	GO:0042813	Wnt-activated receptor activity(GO:0042813)
1.4	42.1	GO:0008392	arachidonic acid epoxygenase activity(GO:0008392)
1.0	39.9	GO:0004364	glutathione transferase activity(GO:0004364)
0.2	36.9	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
2.9	35.3	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.3	29.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
5.6	27.8	GO:0070404	NADH binding(GO:0070404)

Showing 1 to 10 of 68 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	69.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
2.5	47.8	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.8	38.7	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.9	35.3	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.8	25.3	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.4	24.6	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.4	9.7	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	6.1	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.1	4.4	PID RAS PATHWAY	Regulation of Ras family activation
0.6	4.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Showing 1 to 10 of 16 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
12.8	102.7	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
2.4	47.8	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
2.7	27.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
1.4	26.6	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
1.4	25.2	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.8	22.5	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
1.0	16.3	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.2	16.2	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.5	14.8	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.2	14.8	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK

Showing 1 to 10 of 29 entries

Results for T

Z-value: 1.20

Motif logo

Transcription factors associated with T

Activity-expression correlation:

Activity profile of T motif

Sorted Z-values of T motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of T

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: