ISMARA results: Stat6

Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation

Downloads

Results for Stat6

Z-value: 0.84

Motif logo

Transcription factors associated with Stat6

Gene Symbol	Gene ID	Gene Info
Stat6 NCBI RGD Ensembl	ENSRNOG00000025023	signal transducer and activator of transcription 6

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Stat6	rn6_v1_chr7_+_70950231_70950231	0.14	1.4e-02	Click!

Activity profile of Stat6 motif

Sorted Z-values of Stat6 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr3_-_63568464 Show fit	30.76	ENSRNOT00000068494	AABR07052585.2 NCBI RGD Ensembl Show fit
chr16_-_18766174 Show fit	27.40	ENSRNOT00000084813	Sftpd NCBI RGD Ensembl Show fit	surfactant protein D
chr18_-_61057365 Show fit	22.89	ENSRNOT00000042352	Alpk2 NCBI RGD Ensembl Show fit	alpha-kinase 2
chr1_-_88066101 Show fit	22.03	ENSRNOT00000079473 ENSRNOT00000027893	Ryr1 NCBI RGD Ensembl Show fit	ryanodine receptor 1
chr6_+_56625650 Show fit	21.90	ENSRNOT00000008803	Meox2 NCBI RGD Ensembl Show fit	mesenchyme homeobox 2
chr1_-_198233588 Show fit	18.22	ENSRNOT00000088473	Aldoa NCBI RGD Ensembl Show fit	aldolase, fructose-bisphosphate A
chr1_-_198233215 Show fit	17.81	ENSRNOT00000087928	Aldoa NCBI RGD Ensembl Show fit	aldolase, fructose-bisphosphate A
chr4_-_148437961 Show fit	17.52	ENSRNOT00000082907	Alox5 NCBI RGD Ensembl Show fit	arachidonate 5-lipoxygenase
chr1_-_143392532 Show fit	16.50	ENSRNOT00000026089	Fsd2 NCBI RGD Ensembl Show fit	fibronectin type III and SPRY domain containing 2
chr2_+_199162745 Show fit	16.40	ENSRNOT00000023488	Gja5 NCBI RGD Ensembl Show fit	gap junction protein, alpha 5

Showing 1 to 10 of 164 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Stat6

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
2.6	36.0	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
5.5	27.4	GO:0050828	regulation of liquid surface tension(GO:0050828)
3.1	22.0	GO:0071313	cellular response to caffeine(GO:0071313)
4.4	21.9	GO:0001757	somite specification(GO:0001757)
1.8	21.4	GO:0032534	regulation of microvillus assembly(GO:0032534)
4.4	17.5	GO:0002540	leukotriene production involved in inflammatory response(GO:0002540)
5.5	16.4	GO:0010643	cell communication by chemical coupling(GO:0010643)
5.4	16.3	GO:0001807	regulation of type IV hypersensitivity(GO:0001807)
0.2	16.0	GO:0048662	negative regulation of smooth muscle cell proliferation(GO:0048662)
0.5	14.1	GO:0019835	cytolysis(GO:0019835)

Showing 1 to 10 of 68 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	36.0	GO:0035686	sperm fibrous sheath(GO:0035686)
0.1	35.1	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.7	27.4	GO:0005771	multivesicular body(GO:0005771)
0.1	22.6	GO:0016607	nuclear speck(GO:0016607)
2.4	22.0	GO:0030314	junctional membrane complex(GO:0030314)
1.8	17.5	GO:0005641	nuclear envelope lumen(GO:0005641)
0.8	16.4	GO:0005922	connexon complex(GO:0005922)
2.3	14.1	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
2.2	13.3	GO:0016012	sarcoglycan complex(GO:0016012)
3.1	12.6	GO:0005606	laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)

Showing 1 to 10 of 35 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
5.1	36.0	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.1	30.6	GO:0004252	serine-type endopeptidase activity(GO:0004252)
1.1	27.4	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	22.3	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
5.5	22.0	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.5	21.9	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
5.8	17.5	GO:0004051	arachidonate 5-lipoxygenase activity(GO:0004051)
4.1	16.4	GO:0055077	gap junction hemi-channel activity(GO:0055077) gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
5.4	16.3	GO:0042015	interleukin-20 binding(GO:0042015)
0.0	16.2	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)

Showing 1 to 10 of 62 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	36.0	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.6	22.0	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.4	19.9	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.3	14.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.7	12.6	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	11.1	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3	10.7	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	10.0	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2	7.7	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.3	7.5	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Showing 1 to 10 of 22 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	36.7	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.9	16.4	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
1.0	14.6	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	12.6	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
1.0	11.8	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	10.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2	9.4	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.4	6.7	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.3	6.4	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.3	5.8	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events

Showing 1 to 10 of 18 entries

Results for Stat6

Z-value: 0.84

Motif logo

Transcription factors associated with Stat6

Activity-expression correlation:

Activity profile of Stat6 motif

Sorted Z-values of Stat6 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Stat6

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: