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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Stat5a

Z-value: 1.36

Motif logo

Transcription factors associated with Stat5a

Gene Symbol Gene ID Gene Info
ENSRNOG00000019496 signal transducer and activator of transcription 5A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Stat5arn6_v1_chr10_+_88764732_88764732-0.204.1e-04Click!

Activity profile of Stat5a motif

Sorted Z-values of Stat5a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_70776046 44.33 ENSRNOT00000040403
protease, serine 1
chr16_+_6970342 44.27 ENSRNOT00000061294
ENSRNOT00000048344
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr2_+_54466280 43.66 ENSRNOT00000033112
complement C6
chr16_+_54164431 41.88 ENSRNOT00000090763
fibrinogen-like 1
chr2_+_181987217 31.44 ENSRNOT00000034521
fibrinogen gamma chain
chr2_+_104744461 31.04 ENSRNOT00000016083
ENSRNOT00000082627
ceruloplasmin
chr3_-_63836017 30.86 ENSRNOT00000030978

chr13_-_47397890 30.21 ENSRNOT00000005505
complement component 4 binding protein, beta
chr5_-_77492013 30.08 ENSRNOT00000012293
alpha-2u globulin PGCL5
chr8_-_52937972 30.00 ENSRNOT00000007789
nicotinamide N-methyltransferase
chr4_+_70689737 26.51 ENSRNOT00000018852
protease, serine, 2
chr2_+_147496229 26.32 ENSRNOT00000022105
transmembrane 4 L six family member 4
chr1_+_229030233 26.31 ENSRNOT00000084503
glycine-N-acyltransferase-like 1
chr8_-_111777602 26.11 ENSRNOT00000052317
ENSRNOT00000083855
similar to RIKEN cDNA 1300017J02
chr4_-_23122725 23.95 ENSRNOT00000089086
STEAP4 metalloreductase
chr4_+_109497962 23.17 ENSRNOT00000057869
regenerating family member 1 alpha
chr6_-_128003418 23.10 ENSRNOT00000013896
serine (or cysteine) proteinase inhibitor, clade A, member 3C
chr4_-_161850875 22.76 ENSRNOT00000009467
pregnancy-zone protein
chr6_-_127656603 22.37 ENSRNOT00000015516
serpin family A member 11
chr4_+_163162211 22.13 ENSRNOT00000082537
C-type lectin domain family 1, member B
chr1_-_76780230 22.06 ENSRNOT00000002046
alcohol sulfotransferase-like
chr10_-_98544447 22.02 ENSRNOT00000073149
ATP binding cassette subfamily A member 6
chrX_-_64800435 21.96 ENSRNOT00000005663
ankyrin repeat and SOCS box-containing 12
chr2_+_55775274 21.79 ENSRNOT00000018545
complement C9
chr3_-_55587946 21.72 ENSRNOT00000075107
ATP binding cassette subfamily B member 11
chr4_-_78879294 21.38 ENSRNOT00000084543
insulin-like growth factor 2 mRNA binding protein 3
chr9_+_100285804 21.07 ENSRNOT00000079305
alanine-glyoxylate aminotransferase
chr3_-_63568464 21.06 ENSRNOT00000068494

chr1_+_83744238 20.71 ENSRNOT00000028249
cytochrome P450, family 2, subfamily a, polypeptide 1
chr6_+_127927650 20.55 ENSRNOT00000057271
serine protease inhibitor A3F-like
chr4_+_154215250 20.10 ENSRNOT00000072465
murinoglobulin 2
chr5_-_52767592 20.07 ENSRNOT00000048383
alpha2u globulin
chr15_-_46432965 20.05 ENSRNOT00000014320
GATA binding protein 4
chr10_+_65767930 19.39 ENSRNOT00000039954
vitronectin
chr2_-_180914940 19.36 ENSRNOT00000015732
tryptophan 2,3-dioxygenase
chr2_+_182006242 19.35 ENSRNOT00000064091
fibrinogen alpha chain
chr16_+_50152008 19.25 ENSRNOT00000019237
kallikrein B1
chr10_+_11240138 19.19 ENSRNOT00000048687
sarcalumenin
chr2_+_104416972 18.96 ENSRNOT00000017125
tripartite motif-containing 55
chr5_-_77408323 18.79 ENSRNOT00000046857
ENSRNOT00000046760
alpha-2u globulin PGCL5
major urinary protein 4
chr2_-_105089659 18.76 ENSRNOT00000043381
carboxypeptidase B1
chr5_-_77248563 18.67 ENSRNOT00000052243
alpha-2u globulin PGCL5
chrX_-_65400298 18.59 ENSRNOT00000032121
V-set and immunoglobulin domain containing 4
chr19_+_15195565 18.59 ENSRNOT00000090865
ENSRNOT00000078874
carboxylesterase 1D
chr16_+_18690246 18.57 ENSRNOT00000081484
methionine adenosyltransferase 1A
chr19_+_15294248 18.20 ENSRNOT00000024622
carboxylesterase 1F
chr10_+_109707962 17.97 ENSRNOT00000054962
ENSRNOT00000088898
glucagon receptor
chr6_+_128048099 17.60 ENSRNOT00000084685
ENSRNOT00000087017
Ab1-233
chr1_+_213577122 17.29 ENSRNOT00000071925
similar to transthyretin (4L369)
chr14_+_17195014 17.28 ENSRNOT00000031667
C-X-C motif chemokine ligand 11
chr9_-_65790347 17.23 ENSRNOT00000028506

chr8_-_37450340 17.19 ENSRNOT00000072224
urinary protein 3-like
chr16_-_56900052 16.66 ENSRNOT00000017339
macrophage scavenger receptor 1
chr19_-_43911057 16.56 ENSRNOT00000026017
chymotrypsinogen B1
chr11_-_60819249 16.45 ENSRNOT00000043917
ENSRNOT00000042447
CD200 receptor 1-like
chr8_-_132910905 16.17 ENSRNOT00000008630
FYVE and coiled-coil domain containing 1
chr1_-_259287684 16.08 ENSRNOT00000054724
cytochrome P450, family 2, subfamily c, polypeptide 22
chr11_-_64952687 16.01 ENSRNOT00000087892
popeye domain containing 2
chr11_-_81717521 15.64 ENSRNOT00000058422
alpha-2-HS-glycoprotein
chr4_-_69196430 15.62 ENSRNOT00000017673
Trypsin V-A
chr1_-_258877045 15.54 ENSRNOT00000071633
cytochrome P450, family 2, subfamily c, polypeptide 13
chr14_-_80973456 15.45 ENSRNOT00000013257
HGF activator
chr2_+_248398917 15.44 ENSRNOT00000045855
guanylate binding protein 1
chr6_+_23337571 15.38 ENSRNOT00000011832
similar to hypothetical protein MGC38716
chr5_-_77342299 15.37 ENSRNOT00000075994
similar to alpha-2u-globulin
chr9_+_53013413 15.36 ENSRNOT00000005313
ankyrin and armadillo repeat containing
chr2_-_210749991 14.98 ENSRNOT00000051261
ENSRNOT00000052403
glutathione S-transferase, mu 6-like
chr5_-_77316764 14.91 ENSRNOT00000071395
ENSRNOT00000076464
major urinary protein 4
chr11_+_74057361 14.78 ENSRNOT00000048746
carboxypeptidase N subunit 2
chr6_-_127508452 14.77 ENSRNOT00000073709
protein Z-dependent protease inhibitor-like
chr4_-_23135354 14.64 ENSRNOT00000011432
STEAP4 metalloreductase
chr4_-_129619142 14.63 ENSRNOT00000047453
leiomodin 3
chr16_+_83358116 14.61 ENSRNOT00000031109
RAB20, member RAS oncogene family
chr13_-_56877611 14.43 ENSRNOT00000079040
ENSRNOT00000017195
complement factor H-related 1
chr19_+_27404712 14.37 ENSRNOT00000023657
myosin light chain kinase 3
chr10_+_53818818 14.28 ENSRNOT00000057260
myosin heavy chain 8
chr13_-_80862963 14.28 ENSRNOT00000004864
flavin containing monooxygenase 3
chr1_-_89369960 14.10 ENSRNOT00000028545
hepcidin antimicrobial peptide
chr8_-_77398156 14.08 ENSRNOT00000091858
ENSRNOT00000085349
ENSRNOT00000082763
lipase C, hepatic type
chr6_-_24676524 13.99 ENSRNOT00000047853
calpain 13
chr1_+_201687758 13.92 ENSRNOT00000093308
deleted in malignant brain tumors 1
chr1_-_73619356 13.89 ENSRNOT00000074352
leukocyte immunoglobulin like receptor B3
chr4_+_109467272 13.75 ENSRNOT00000008212
regenerating family member 3 beta
chr1_-_104157855 13.57 ENSRNOT00000019311
cysteine and glycine rich protein 3
chr2_+_92574038 13.54 ENSRNOT00000089422
GTPase activating protein testicular GAP1
chr6_+_127946686 13.47 ENSRNOT00000082680
Ab1-233
chr8_+_2659865 13.30 ENSRNOT00000088553
ENSRNOT00000010243
caspase 12
chr3_+_53563194 13.26 ENSRNOT00000048300
xin actin-binding repeat containing 2
chr4_-_78759408 13.15 ENSRNOT00000050994
insulin-like growth factor 2 mRNA binding protein 3
chr8_-_128711221 13.11 ENSRNOT00000055888
xin actin-binding repeat containing 1
chr4_-_30338679 13.08 ENSRNOT00000012050
paraoxonase 3
chr1_+_64506735 13.01 ENSRNOT00000086331
NLR family, pyrin domain containing 12
chr15_-_33629699 12.99 ENSRNOT00000023302
myosin heavy chain 6
chr1_+_72882806 12.94 ENSRNOT00000024640
troponin I3, cardiac type
chr5_-_19368431 12.90 ENSRNOT00000012819
cytochrome P450, family 7, subfamily a, polypeptide 1
chrX_+_143097525 12.86 ENSRNOT00000004559
coagulation factor IX
chr10_+_90085559 12.84 ENSRNOT00000028332
N-acetylglutamate synthase
chr1_-_258766881 12.82 ENSRNOT00000015801
cytochrome P450, family 2, subfamily c, polypeptide 12
chr10_-_110274768 12.81 ENSRNOT00000054931
secreted and transmembrane 1A
chr4_-_70659252 12.65 ENSRNOT00000048049
trypsin 10
chr14_+_22517774 12.64 ENSRNOT00000047655
UDP-glucuronosyltransferase 2 family, member 37
chr1_+_277068761 12.60 ENSRNOT00000044183
ENSRNOT00000022382
hyaluronan binding protein 2
chr17_-_417480 12.56 ENSRNOT00000023685
fructose-bisphosphatase 1
chr3_-_71295575 12.48 ENSRNOT00000040303
ENSRNOT00000083015
zinc finger, SWIM-type containing 2
chr2_-_182035032 12.46 ENSRNOT00000009813
fibrinogen beta chain
chr15_-_34392066 12.42 ENSRNOT00000027315
transglutaminase 1
chr1_+_189364288 12.35 ENSRNOT00000080338
acyl-CoA synthetase medium-chain family member 1
chr2_+_140708397 12.35 ENSRNOT00000088846
microsomal glutathione S-transferase 2
chr1_-_169334093 12.31 ENSRNOT00000032587
ubiquilin 3
chr9_+_15582564 12.24 ENSRNOT00000020640
uncharacterized LOC100912849
chr20_+_13778178 12.23 ENSRNOT00000058314
glutathione S-transferase, theta 4
chr1_+_189241593 12.06 ENSRNOT00000046025
acyl-CoA synthetase medium-chain family member 5
chr8_+_116857684 12.04 ENSRNOT00000026711
macrophage stimulating 1
chr1_-_224389389 11.94 ENSRNOT00000077408
ENSRNOT00000050010
integral membrane transport protein UST4r
chrX_-_14220662 11.85 ENSRNOT00000045753
sushi-repeat-containing protein, X-linked
chr11_+_7422272 11.81 ENSRNOT00000075964
1,4-alpha-glucan branching enzyme 1
chr6_+_2216623 11.78 ENSRNOT00000008045
regulator of microtubule dynamics 2
chr16_-_7026540 11.78 ENSRNOT00000051751
inter-alpha trypsin inhibitor, heavy chain 1
chr4_+_70614524 11.74 ENSRNOT00000041100
protease, serine 3
chr10_+_64952119 11.67 ENSRNOT00000012154
pipecolic acid and sarcosine oxidase
chr10_-_34221928 11.66 ENSRNOT00000045545
immunity-related GTPase M
chr1_+_72874583 11.51 ENSRNOT00000077719
dynein, axonemal, assembly factor 3
chr9_-_27452902 11.50 ENSRNOT00000018325
glutathione S-transferase alpha 1
chr11_+_62584959 11.48 ENSRNOT00000071065
GRAM domain containing 1C
chr13_+_75175254 11.46 ENSRNOT00000044008
SEC16 homolog B, endoplasmic reticulum export factor
chrX_-_64726210 11.43 ENSRNOT00000076012
ENSRNOT00000086265
ankyrin repeat and SOCS box-containing 12
chr14_+_20266891 11.42 ENSRNOT00000004174
group specific component
chr7_-_118840634 11.32 ENSRNOT00000031568
apolipoprotein L 11a
chr4_-_30556814 11.32 ENSRNOT00000012760
pyruvate dehydrogenase kinase 4
chr4_+_70755795 11.31 ENSRNOT00000043527
similar to Anionic trypsin II precursor (Pretrypsinogen II)
chr3_-_37854561 11.27 ENSRNOT00000076095
nebulin
chr7_+_28066635 11.17 ENSRNOT00000005844
phenylalanine hydroxylase
chr13_-_56693968 11.17 ENSRNOT00000060160

chr5_+_124476168 11.06 ENSRNOT00000077754
similar to novel protein
chr1_-_78180216 10.99 ENSRNOT00000071576
complement component 5a receptor 2
chr5_-_4975436 10.96 ENSRNOT00000062006
XK related 9
chr13_+_83721300 10.95 ENSRNOT00000082677
adenylate cyclase 10 (soluble)
chr13_-_57080491 10.93 ENSRNOT00000017749
ENSRNOT00000086572
ENSRNOT00000060111
complement factor H
chr1_+_213511874 10.93 ENSRNOT00000078080
ENSRNOT00000016883
cytochrome P450, family 2, subfamily e, polypeptide 1
chr2_-_93641497 10.83 ENSRNOT00000013720
charged multivesicular body protein 4C
chr9_+_95221474 10.83 ENSRNOT00000066839
UDP glucuronosyltransferase family 1 member A5
chr10_+_4951557 10.78 ENSRNOT00000003451
protamine 3
chr20_+_26999795 10.75 ENSRNOT00000057872
myopalladin
chr13_+_83073544 10.74 ENSRNOT00000066119
ENSRNOT00000079796
ENSRNOT00000077070
dermatopontin
chr2_-_191294374 10.71 ENSRNOT00000067469
similar to S100 calcium-binding protein, ventral prostate
chr10_-_98469799 10.69 ENSRNOT00000087502
ENSRNOT00000088646
ATP binding cassette subfamily A member 9
chr9_-_4327679 10.69 ENSRNOT00000073468
sulfotransferase 1C1-like
chr10_+_56662561 10.66 ENSRNOT00000025254
asialoglycoprotein receptor 1
chr14_+_22806132 10.60 ENSRNOT00000002728
UDP glucuronosyltransferase 2 family, polypeptide B10
chr16_-_19942343 10.53 ENSRNOT00000087162
ENSRNOT00000091906
bone marrow stromal cell antigen 2
chr16_+_23317953 10.50 ENSRNOT00000075287

chr16_+_74531564 10.48 ENSRNOT00000078971
solute carrier family 25 member 15
chr9_+_14529218 10.48 ENSRNOT00000016893
apolipoprotein B mRNA editing enzyme catalytic subunit 2
chr7_-_117680004 10.47 ENSRNOT00000040422
solute carrier family 39 member 4
chr15_+_42659371 10.45 ENSRNOT00000091612
clusterin
chr16_-_20807070 10.42 ENSRNOT00000072536
cartilage oligomeric matrix protein
chr3_+_95232166 10.40 ENSRNOT00000017952
hypothetical protein LOC691083
chr2_-_22147115 10.39 ENSRNOT00000017408
spermatogenic leucine zipper 1
chr2_-_54823917 10.36 ENSRNOT00000039057
ENSRNOT00000079333
caspase recruitment domain family, member 6
chr9_-_43116521 10.31 ENSRNOT00000039437
ankyrin repeat domain 23
chr9_+_95233957 10.28 ENSRNOT00000071003
UDP glucuronosyltransferase family 1 member A5
chr1_+_203160323 10.26 ENSRNOT00000027919

chr13_+_83073866 10.25 ENSRNOT00000075996
dermatopontin
chr14_-_60276794 10.24 ENSRNOT00000048509
solute carrier family 34 member 2
chr18_-_29562153 10.06 ENSRNOT00000023977
CD14 molecule
chr3_-_101474890 10.03 ENSRNOT00000091869
gamma-butyrobetaine hydroxylase 1
chr13_-_50499060 9.99 ENSRNOT00000065347
ENSRNOT00000076924
ethanolamine kinase 2
chr8_-_132911193 9.97 ENSRNOT00000087799
FYVE and coiled-coil domain containing 1
chr5_-_77433847 9.95 ENSRNOT00000076906
ENSRNOT00000043056
similar to alpha-2u globulin PGCL2
major urinary protein 4
chr7_+_1206648 9.94 ENSRNOT00000073689
protein S (alpha)
chr2_+_87418517 9.93 ENSRNOT00000048046
tyrosine-protein phosphatase non-receptor type substrate 1-like
chr1_-_189359730 9.91 ENSRNOT00000066597
RGD1559600
chr1_-_98493978 9.86 ENSRNOT00000023942
natural killer cell granule protein 7
chr20_-_4561062 9.78 ENSRNOT00000065044
ENSRNOT00000092698
ENSRNOT00000060607
complement factor B
complement C2
chr2_-_60683451 9.75 ENSRNOT00000046215
retinoic acid induced 14
chr6_+_56846789 9.63 ENSRNOT00000032108
alkylglycerol monooxygenase
chr8_-_54998864 9.62 ENSRNOT00000059191
testis expressed 12
chr16_-_74963044 9.60 ENSRNOT00000018362
coiled-coil domain containing 70
chr1_+_101502987 9.58 ENSRNOT00000085005
tubby-like protein 2
chrX_-_98095663 9.57 ENSRNOT00000004491
RNA binding motif 31, Y-linked
chr14_+_7113544 9.53 ENSRNOT00000038188
hydroxysteroid (17-beta) dehydrogenase 13
chr6_+_10642700 9.44 ENSRNOT00000040329
karyopherin alpha 2-like
chr14_+_22375955 9.43 ENSRNOT00000063915
ENSRNOT00000034784
UDP-glucuronosyltransferase 2 family, member 37
chr1_+_72784966 9.43 ENSRNOT00000090065
ENSRNOT00000041527
transmembrane protein 86B
chr1_-_169344306 9.40 ENSRNOT00000022852
ubiquilin-like
chr13_+_75177965 9.39 ENSRNOT00000007321
SEC16 homolog B, endoplasmic reticulum export factor
chr20_-_3793985 9.37 ENSRNOT00000049540
ENSRNOT00000086293
RT1 class I, locus CE16
chr11_+_61609370 9.37 ENSRNOT00000088880
ENSRNOT00000082533
GRAM domain containing 1C
chr3_+_79678201 9.33 ENSRNOT00000087604
ENSRNOT00000079709
mitochondrial carrier 2
chr17_-_69827112 9.28 ENSRNOT00000023835
aldo-keto reductase family 1, member C14
chr1_+_264893162 9.28 ENSRNOT00000021714
T-cell leukemia, homeobox 1
chr7_-_140090922 9.27 ENSRNOT00000014456
lactalbumin, alpha
chr15_-_35394792 9.23 ENSRNOT00000028058
granzyme C
chr13_-_91427575 9.21 ENSRNOT00000012092
amyloid P component, serum
chr1_-_73660593 9.19 ENSRNOT00000038802
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr7_-_124999137 9.19 ENSRNOT00000039228
patatin-like phospholipase domain containing 5
chr10_+_34277993 9.09 ENSRNOT00000055872
ENSRNOT00000003343
interferon gamma inducible protein 47
chr4_-_68349273 9.02 ENSRNOT00000016251
protease, serine, 37
chr1_-_80594136 9.00 ENSRNOT00000024800
apolipoprotein C2
chr13_-_27653839 8.98 ENSRNOT00000071638
signal-regulatory protein alpha-like

Network of associatons between targets according to the STRING database.

First level regulatory network of Stat5a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
14.6 43.7 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
14.1 14.1 GO:0034760 negative regulation of iron ion transmembrane transport(GO:0034760)
10.1 30.2 GO:0045959 negative regulation of complement activation, classical pathway(GO:0045959)
8.4 25.2 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
7.0 21.1 GO:0019265 glycine biosynthetic process, by transamination of glyoxylate(GO:0019265) oxalic acid secretion(GO:0046724)
6.7 20.1 GO:0035054 septum secundum development(GO:0003285) embryonic heart tube anterior/posterior pattern specification(GO:0035054) negative regulation of connective tissue replacement(GO:1905204)
6.4 31.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
6.2 18.6 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
5.5 21.8 GO:0046351 disaccharide biosynthetic process(GO:0046351)
5.3 16.0 GO:0060931 sinoatrial node cell development(GO:0060931)
5.1 5.1 GO:0042853 L-alanine catabolic process(GO:0042853)
4.9 44.4 GO:0052697 xenobiotic glucuronidation(GO:0052697)
4.8 33.8 GO:0009804 coumarin metabolic process(GO:0009804)
4.8 19.2 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
4.7 14.1 GO:0010034 response to acetate(GO:0010034)
4.5 13.6 GO:1903919 regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919)
4.5 13.5 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
4.5 8.9 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
4.3 13.0 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
4.3 13.0 GO:1905242 response to 3,3',5-triiodo-L-thyronine(GO:1905242) cellular response to 3,3',5-triiodo-L-thyronine(GO:1905243)
4.1 32.6 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
4.0 4.0 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
4.0 12.0 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
4.0 15.9 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
3.9 11.7 GO:0019474 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
3.8 3.8 GO:0006532 aspartate biosynthetic process(GO:0006532)
3.7 33.7 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
3.7 18.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
3.7 29.6 GO:0015679 plasma membrane copper ion transport(GO:0015679)
3.7 11.0 GO:0071623 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024)
3.7 11.0 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
3.6 18.1 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
3.5 24.8 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
3.5 10.5 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
3.5 31.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
3.5 10.5 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
3.5 10.5 GO:1902996 regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949) neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996) positive regulation of neurofibrillary tangle assembly(GO:1902998)
3.4 17.2 GO:0006526 arginine biosynthetic process(GO:0006526)
3.4 13.8 GO:1903576 response to L-arginine(GO:1903576)
3.2 9.6 GO:0036102 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
3.2 6.4 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
3.1 6.3 GO:0072719 cellular response to cisplatin(GO:0072719)
3.1 21.7 GO:0015722 canalicular bile acid transport(GO:0015722)
3.1 67.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
3.0 21.2 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
3.0 9.0 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
3.0 8.9 GO:0060545 positive regulation of necroptotic process(GO:0060545)
3.0 14.8 GO:0000066 mitochondrial ornithine transport(GO:0000066)
2.9 8.8 GO:0035697 CD8-positive, alpha-beta T cell extravasation(GO:0035697)
2.9 8.7 GO:0060764 cell-cell signaling involved in mammary gland development(GO:0060764)
2.9 69.1 GO:0030574 collagen catabolic process(GO:0030574)
2.9 11.5 GO:1904975 response to bleomycin(GO:1904975)
2.9 14.4 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
2.9 20.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
2.8 25.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
2.8 27.5 GO:0046060 dATP metabolic process(GO:0046060)
2.8 19.3 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
2.7 8.2 GO:0002434 immune complex clearance(GO:0002434)
2.7 8.2 GO:0051012 microtubule sliding(GO:0051012)
2.7 21.4 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
2.6 10.6 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
2.6 5.2 GO:0002488 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
2.6 15.4 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
2.5 14.9 GO:0002457 T cell antigen processing and presentation(GO:0002457)
2.5 5.0 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
2.5 7.4 GO:0046968 cytosol to ER transport(GO:0046967) peptide antigen transport(GO:0046968)
2.5 7.4 GO:0014016 neuroblast differentiation(GO:0014016)
2.5 7.4 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
2.4 14.7 GO:0090383 phagosome acidification(GO:0090383)
2.4 14.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
2.4 14.5 GO:0034059 response to anoxia(GO:0034059)
2.4 9.4 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
2.4 7.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
2.3 9.2 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
2.3 6.8 GO:1901377 toxin catabolic process(GO:0009407) mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) secondary metabolite catabolic process(GO:0090487) organic heteropentacyclic compound catabolic process(GO:1901377)
2.3 4.5 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
2.2 13.1 GO:0035701 hematopoietic stem cell migration(GO:0035701)
2.2 2.2 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
2.2 36.8 GO:0001887 selenium compound metabolic process(GO:0001887)
2.2 6.5 GO:0055073 cadmium ion homeostasis(GO:0055073)
2.1 6.3 GO:0002462 tolerance induction to nonself antigen(GO:0002462)
2.1 6.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
2.1 12.4 GO:0010266 response to vitamin B1(GO:0010266)
2.1 10.3 GO:0060297 regulation of sarcomere organization(GO:0060297)
2.1 6.2 GO:0060468 prevention of polyspermy(GO:0060468)
2.0 6.1 GO:1990743 protein sialylation(GO:1990743)
2.0 6.0 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
2.0 18.0 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
2.0 18.0 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
2.0 41.3 GO:0035634 response to stilbenoid(GO:0035634)
1.9 15.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
1.9 5.7 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
1.9 5.7 GO:1903334 positive regulation of protein folding(GO:1903334)
1.9 7.5 GO:1901423 response to benzene(GO:1901423)
1.8 7.4 GO:0044243 multicellular organism catabolic process(GO:0044243)
1.8 5.5 GO:0019303 D-ribose catabolic process(GO:0019303)
1.8 12.6 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
1.8 8.9 GO:0006642 triglyceride mobilization(GO:0006642)
1.8 7.1 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) notochord formation(GO:0014028)
1.7 34.9 GO:0001833 inner cell mass cell proliferation(GO:0001833)
1.7 7.0 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
1.7 3.5 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
1.7 5.2 GO:0006552 leucine catabolic process(GO:0006552)
1.7 5.2 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
1.7 5.2 GO:2000384 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
1.7 8.6 GO:0050828 regulation of liquid surface tension(GO:0050828)
1.7 5.1 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
1.7 6.7 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
1.7 3.3 GO:0010643 cell communication by chemical coupling(GO:0010643)
1.7 11.6 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
1.6 6.6 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
1.6 3.2 GO:1901143 insulin catabolic process(GO:1901143)
1.6 4.8 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
1.6 17.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
1.6 4.8 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
1.6 1.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
1.6 19.1 GO:0046485 ether lipid metabolic process(GO:0046485)
1.6 14.3 GO:0030049 muscle filament sliding(GO:0030049)
1.6 45.5 GO:0030212 hyaluronan metabolic process(GO:0030212)
1.6 6.2 GO:0035552 oxidative RNA demethylation(GO:0035513) oxidative single-stranded DNA demethylation(GO:0035552) oxidative single-stranded RNA demethylation(GO:0035553)
1.6 7.8 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
1.6 23.4 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
1.6 6.2 GO:0034240 negative regulation of macrophage fusion(GO:0034240)
1.6 4.7 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
1.5 6.1 GO:0071724 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
1.5 6.0 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
1.5 12.0 GO:0006559 L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
1.5 4.4 GO:0051977 lysophospholipid transport(GO:0051977)
1.5 10.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
1.5 11.8 GO:0001845 phagolysosome assembly(GO:0001845)
1.4 7.2 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
1.4 7.2 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
1.4 2.9 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
1.4 12.9 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
1.4 2.8 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
1.4 15.6 GO:0006068 ethanol catabolic process(GO:0006068)
1.4 4.3 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
1.4 4.2 GO:0006214 thymidine catabolic process(GO:0006214) pyrimidine deoxyribonucleoside catabolic process(GO:0046127)
1.4 21.0 GO:0015671 oxygen transport(GO:0015671)
1.4 18.2 GO:0006750 glutathione biosynthetic process(GO:0006750)
1.4 5.6 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
1.4 5.5 GO:0018992 germ-line sex determination(GO:0018992)
1.4 5.5 GO:0032827 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
1.4 9.7 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
1.4 5.5 GO:0052314 isoquinoline alkaloid metabolic process(GO:0033076) phytoalexin metabolic process(GO:0052314)
1.4 9.6 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.4 13.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.4 5.4 GO:0023021 termination of signal transduction(GO:0023021)
1.4 4.1 GO:0048865 stem cell fate commitment(GO:0048865)
1.3 4.0 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
1.3 5.4 GO:0015747 urate transport(GO:0015747)
1.3 17.3 GO:0010818 T cell chemotaxis(GO:0010818)
1.3 6.6 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
1.3 3.9 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
1.3 9.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
1.3 3.9 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
1.3 3.9 GO:0045575 basophil activation(GO:0045575)
1.3 6.5 GO:0035627 ceramide transport(GO:0035627)
1.3 47.8 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
1.3 6.5 GO:0060235 lens induction in camera-type eye(GO:0060235)
1.3 15.4 GO:0033623 regulation of integrin activation(GO:0033623)
1.3 6.4 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
1.3 1.3 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
1.3 5.1 GO:0050711 negative regulation of interleukin-1 secretion(GO:0050711)
1.3 2.5 GO:0001802 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
1.3 7.6 GO:0060481 lobar bronchus epithelium development(GO:0060481)
1.3 1.3 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
1.3 5.0 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
1.3 8.8 GO:0071415 cellular response to purine-containing compound(GO:0071415)
1.2 3.6 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
1.2 3.6 GO:0031989 bombesin receptor signaling pathway(GO:0031989)
1.2 5.9 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
1.2 4.7 GO:0030916 otic vesicle formation(GO:0030916)
1.2 4.7 GO:0060178 regulation of exocyst localization(GO:0060178)
1.2 18.6 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
1.2 25.6 GO:0030220 platelet formation(GO:0030220)
1.2 5.8 GO:0030070 insulin processing(GO:0030070)
1.2 3.5 GO:0006431 methionyl-tRNA aminoacylation(GO:0006431)
1.2 11.5 GO:0042178 xenobiotic catabolic process(GO:0042178)
1.1 4.6 GO:1904158 axonemal central apparatus assembly(GO:1904158)
1.1 3.4 GO:0006106 fumarate metabolic process(GO:0006106)
1.1 3.4 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
1.1 1.1 GO:0060374 mast cell differentiation(GO:0060374) regulation of mast cell differentiation(GO:0060375)
1.1 2.2 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
1.1 12.3 GO:2000257 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
1.1 16.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
1.1 9.9 GO:0042730 fibrinolysis(GO:0042730)
1.1 1.1 GO:1903972 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
1.1 2.2 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
1.1 2.2 GO:0015677 copper ion import(GO:0015677) copper ion export(GO:0060003)
1.1 5.4 GO:0080154 regulation of fertilization(GO:0080154)
1.1 17.2 GO:0009750 response to fructose(GO:0009750)
1.1 10.7 GO:0048739 cardiac muscle fiber development(GO:0048739)
1.1 5.4 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
1.1 4.2 GO:1902336 positive regulation of retinal ganglion cell axon guidance(GO:1902336)
1.0 5.2 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
1.0 4.2 GO:0010992 ubiquitin homeostasis(GO:0010992)
1.0 2.1 GO:1901856 negative regulation of cellular respiration(GO:1901856)
1.0 3.1 GO:0042732 D-xylose metabolic process(GO:0042732)
1.0 5.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
1.0 3.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
1.0 3.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
1.0 3.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.0 2.0 GO:0010899 regulation of phosphatidylcholine catabolic process(GO:0010899)
1.0 3.9 GO:1990375 baculum development(GO:1990375)
1.0 2.9 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
1.0 6.7 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
1.0 4.8 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
1.0 2.9 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.9 1.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.9 6.6 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.9 2.8 GO:0018282 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.9 9.3 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.9 23.2 GO:0019835 cytolysis(GO:0019835)
0.9 2.8 GO:1901367 response to L-cysteine(GO:1901367)
0.9 9.2 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.9 10.0 GO:0030259 lipid glycosylation(GO:0030259)
0.9 1.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.9 3.5 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.9 27.3 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.9 8.8 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.9 3.5 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.9 0.9 GO:1903796 negative regulation of inorganic anion transmembrane transport(GO:1903796)
0.9 6.0 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.9 3.4 GO:0044691 tooth eruption(GO:0044691)
0.9 6.9 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.9 23.0 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.9 8.5 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.8 2.5 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.8 2.5 GO:1904953 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953) canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.8 1.7 GO:0042414 epinephrine metabolic process(GO:0042414)
0.8 3.3 GO:1990646 cellular response to prolactin(GO:1990646)
0.8 2.5 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
0.8 4.1 GO:0007343 egg activation(GO:0007343)
0.8 2.4 GO:0032621 interleukin-18 production(GO:0032621) positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.8 5.7 GO:0090232 positive regulation of spindle checkpoint(GO:0090232) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.8 3.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.8 3.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.8 4.0 GO:0050748 negative regulation of lipoprotein metabolic process(GO:0050748)
0.8 2.4 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.8 4.7 GO:0032700 negative regulation of interleukin-17 production(GO:0032700)
0.8 1.6 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.8 3.1 GO:0090290 regulation of osteoclast proliferation(GO:0090289) positive regulation of osteoclast proliferation(GO:0090290)
0.8 1.5 GO:0072126 positive regulation of glomerular mesangial cell proliferation(GO:0072126)
0.8 14.7 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.8 5.4 GO:0003360 brainstem development(GO:0003360)
0.8 3.8 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.8 10.0 GO:2000194 regulation of female gonad development(GO:2000194)
0.8 2.3 GO:0010813 neuropeptide catabolic process(GO:0010813)
0.8 3.8 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.8 6.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.8 6.9 GO:0086043 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.8 2.3 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.7 5.2 GO:0007144 female meiosis I(GO:0007144)
0.7 2.2 GO:0035425 autocrine signaling(GO:0035425) paracrine signaling(GO:0038001)
0.7 3.7 GO:0015793 glycerol transport(GO:0015793)
0.7 14.0 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.7 2.2 GO:1901318 negative regulation of sperm motility(GO:1901318)
0.7 8.8 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.7 6.6 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.7 2.2 GO:0009822 lipid hydroxylation(GO:0002933) alkaloid catabolic process(GO:0009822)
0.7 4.3 GO:0070417 cellular response to cold(GO:0070417)
0.7 5.0 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.7 2.1 GO:0032916 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916)
0.7 9.0 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.7 4.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.7 6.1 GO:0046549 retinal cone cell development(GO:0046549)
0.7 5.4 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.7 6.7 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.7 2.0 GO:0045054 constitutive secretory pathway(GO:0045054)
0.7 6.6 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.7 17.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.6 4.5 GO:0002329 pre-B cell differentiation(GO:0002329)
0.6 5.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.6 143.9 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.6 3.9 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.6 1.9 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
0.6 4.5 GO:0060017 parathyroid gland development(GO:0060017)
0.6 38.4 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.6 5.1 GO:0015866 ADP transport(GO:0015866)
0.6 1.3 GO:0002215 defense response to nematode(GO:0002215)
0.6 6.9 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.6 6.3 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.6 7.5 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.6 1.8 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.6 10.4 GO:0003417 growth plate cartilage development(GO:0003417)
0.6 6.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.6 11.5 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.6 19.3 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.6 1.8 GO:0060101 negative regulation of phagocytosis, engulfment(GO:0060101)
0.6 4.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.6 7.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.6 26.9 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.6 5.3 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.6 1.8 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.6 6.4 GO:0043032 positive regulation of macrophage activation(GO:0043032)
0.6 2.3 GO:0002741 positive regulation of cytokine secretion involved in immune response(GO:0002741) myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.6 4.1 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.6 3.5 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.6 1.7 GO:0030576 Cajal body organization(GO:0030576)
0.6 1.7 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.6 6.3 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.6 2.3 GO:0070673 response to interleukin-18(GO:0070673)
0.6 5.7 GO:0042747 circadian sleep/wake cycle, REM sleep(GO:0042747)
0.6 1.7 GO:0002669 positive regulation of T cell tolerance induction(GO:0002666) positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.6 2.2 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.6 2.8 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.5 7.1 GO:0019430 removal of superoxide radicals(GO:0019430)
0.5 6.0 GO:0006026 aminoglycan catabolic process(GO:0006026) glycosaminoglycan catabolic process(GO:0006027)
0.5 2.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.5 1.6 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.5 3.7 GO:0001865 NK T cell differentiation(GO:0001865)
0.5 1.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.5 6.4 GO:0006956 complement activation(GO:0006956)
0.5 1.1 GO:0072223 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.5 1.1 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
0.5 2.7 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.5 7.9 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.5 1.6 GO:0018094 protein polyglycylation(GO:0018094)
0.5 1.6 GO:0001705 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.5 7.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.5 5.1 GO:0006783 heme biosynthetic process(GO:0006783)
0.5 3.0 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.5 6.5 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.5 3.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.5 2.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.5 5.4 GO:0001778 plasma membrane repair(GO:0001778)
0.5 2.9 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.5 2.4 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.5 9.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.5 10.5 GO:0017144 drug metabolic process(GO:0017144)
0.5 11.4 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.5 3.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.5 1.9 GO:0007341 penetration of zona pellucida(GO:0007341)
0.5 3.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.5 0.9 GO:0035928 RNA import into mitochondrion(GO:0035927) rRNA import into mitochondrion(GO:0035928)
0.5 1.8 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.5 3.7 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.5 12.4 GO:0045214 sarcomere organization(GO:0045214)
0.5 14.9 GO:0030199 collagen fibril organization(GO:0030199)
0.5 5.4 GO:0015825 L-serine transport(GO:0015825)
0.4 1.3 GO:0071883 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.4 1.3 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.4 0.9 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.4 3.1 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.4 0.9 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.4 12.5 GO:0030261 chromosome condensation(GO:0030261)
0.4 1.3 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.4 7.2 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.4 5.9 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.4 0.8 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.4 2.1 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.4 4.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.4 1.2 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.4 3.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.4 4.1 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.4 4.9 GO:0006544 glycine metabolic process(GO:0006544)
0.4 0.8 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.4 16.2 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.4 1.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.4 5.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.4 5.9 GO:0072520 seminiferous tubule development(GO:0072520)
0.4 6.7 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.4 1.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.4 7.1 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.4 1.6 GO:0060327 cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
0.4 4.3 GO:0000212 meiotic spindle organization(GO:0000212)
0.4 0.8 GO:0052501 killing by symbiont of host cells(GO:0001907) induction of programmed cell death(GO:0012502) disruption by symbiont of host cell(GO:0044004) modulation of programmed cell death in other organism(GO:0044531) modulation of apoptotic process in other organism(GO:0044532) positive regulation of apoptotic process in other organism(GO:0044533) modulation by symbiont of host programmed cell death(GO:0052040) positive regulation by symbiont of host programmed cell death(GO:0052042) modulation by symbiont of host apoptotic process(GO:0052150) positive regulation by symbiont of host apoptotic process(GO:0052151) modulation of programmed cell death in other organism involved in symbiotic interaction(GO:0052248) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) modulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052433) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139)
0.4 1.9 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.4 1.1 GO:0010037 response to carbon dioxide(GO:0010037)
0.4 2.3 GO:0097264 self proteolysis(GO:0097264)
0.4 3.4 GO:0032790 ribosome disassembly(GO:0032790)
0.4 1.9 GO:0010587 miRNA catabolic process(GO:0010587)
0.4 2.6 GO:0072711 cellular response to hydroxyurea(GO:0072711)
0.4 1.9 GO:0036017 response to erythropoietin(GO:0036017)
0.4 5.6 GO:0048240 sperm capacitation(GO:0048240)
0.4 1.1 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.4 1.5 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.4 3.3 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.4 1.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.4 1.5 GO:2000427 regulation of apoptotic cell clearance(GO:2000425) positive regulation of apoptotic cell clearance(GO:2000427)
0.4 9.5 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.4 1.5 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.4 1.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.4 4.0 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.4 2.9 GO:0034214 protein hexamerization(GO:0034214)
0.4 3.2 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.4 1.8 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.4 1.8 GO:0051182 coenzyme transport(GO:0051182)
0.3 3.5 GO:0006105 succinate metabolic process(GO:0006105)
0.3 1.7 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.3 0.7 GO:0030043 actin filament fragmentation(GO:0030043)
0.3 8.0 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.3 2.1 GO:1900115 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.3 5.0 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.3 2.0 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.3 2.3 GO:0071404 cellular response to low-density lipoprotein particle stimulus(GO:0071404)
0.3 1.9 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.3 2.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.3 1.5 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.3 1.5 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.3 0.9 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.3 11.2 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.3 3.0 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541)
0.3 2.7 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.3 1.8 GO:0043383 negative T cell selection(GO:0043383)
0.3 4.8 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.3 7.1 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.3 2.9 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.3 3.8 GO:0009435 NAD biosynthetic process(GO:0009435)
0.3 3.2 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.3 2.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.3 2.9 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.3 2.0 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.3 0.3 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533) positive regulation of MDA-5 signaling pathway(GO:1900245)
0.3 3.1 GO:0010954 positive regulation of protein processing(GO:0010954) positive regulation of protein maturation(GO:1903319)
0.3 2.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.3 2.2 GO:0002579 positive regulation of antigen processing and presentation(GO:0002579)
0.3 1.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.3 3.5 GO:0031424 keratinization(GO:0031424)
0.3 4.8 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.3 1.6 GO:0036492 regulation of translation in response to endoplasmic reticulum stress(GO:0036490) regulation of translation initiation in response to endoplasmic reticulum stress(GO:0036491) eiF2alpha phosphorylation in response to endoplasmic reticulum stress(GO:0036492) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.3 2.9 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.3 3.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.3 3.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 1.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.3 3.4 GO:0006855 drug transmembrane transport(GO:0006855)
0.3 1.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.3 2.9 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.3 1.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.3 2.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.3 1.8 GO:0051764 actin crosslink formation(GO:0051764)
0.3 1.8 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.3 0.8 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3 1.0 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.3 2.0 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.3 1.5 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.3 0.8 GO:0097327 response to antineoplastic agent(GO:0097327)
0.3 0.8 GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228) positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.2 3.7 GO:0021534 cell proliferation in hindbrain(GO:0021534) cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.2 2.2 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.2 1.5 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.2 1.0 GO:0032620 interleukin-17 production(GO:0032620)
0.2 2.4 GO:2000018 regulation of male gonad development(GO:2000018)
0.2 7.7 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.2 307.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 1.4 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.2 3.3 GO:0007567 parturition(GO:0007567)
0.2 3.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 0.5 GO:1904925 positive regulation of macromitophagy(GO:1901526) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.2 2.1 GO:0045056 transcytosis(GO:0045056)
0.2 2.8 GO:0045793 positive regulation of cell size(GO:0045793)
0.2 25.1 GO:0007586 digestion(GO:0007586)
0.2 3.8 GO:0007635 chemosensory behavior(GO:0007635)
0.2 1.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.2 0.7 GO:0072103 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.2 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 1.6 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.2 2.0 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.2 1.0 GO:0034501 protein localization to kinetochore(GO:0034501)
0.2 0.4 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 1.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 0.4 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.2 2.4 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.2 1.4 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.2 1.9 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 1.0 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.2 1.7 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.2 1.9 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.2 1.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 1.3 GO:0042832 defense response to protozoan(GO:0042832)
0.2 2.8 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.2 2.0 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 1.2 GO:0060631 regulation of meiosis I(GO:0060631)
0.2 19.8 GO:0042742 defense response to bacterium(GO:0042742)
0.2 0.2 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.2 1.5 GO:0009566 fertilization(GO:0009566)
0.2 2.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 2.7 GO:0042108 positive regulation of cytokine biosynthetic process(GO:0042108)
0.2 0.8 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.2 1.0 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.2 1.3 GO:0045820 negative regulation of nucleotide catabolic process(GO:0030812) negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.2 2.6 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.2 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.2 2.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.2 4.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.4 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.9 GO:0055094 response to lipoprotein particle(GO:0055094)
0.1 0.4 GO:0016240 autophagosome docking(GO:0016240)
0.1 3.0 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 1.4 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.1 0.7 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.8 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.8 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.8 GO:0046884 luteinizing hormone secretion(GO:0032275) follicle-stimulating hormone secretion(GO:0046884)
0.1 0.8 GO:0044598 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.1 1.1 GO:0018377 protein myristoylation(GO:0018377)
0.1 3.7 GO:0097421 liver regeneration(GO:0097421)
0.1 0.1 GO:0002577 regulation of antigen processing and presentation(GO:0002577)
0.1 0.5 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 1.2 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.1 0.9 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.1 2.7 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 1.3 GO:0033189 response to vitamin A(GO:0033189)
0.1 0.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.4 GO:0050706 positive regulation of interleukin-1 beta production(GO:0032731) positive regulation of interleukin-1 production(GO:0032732) regulation of interleukin-1 beta secretion(GO:0050706) positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.1 3.4 GO:0071806 protein transmembrane transport(GO:0071806)
0.1 0.5 GO:0035973 aggrephagy(GO:0035973)
0.1 1.5 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 0.3 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.5 GO:0019516 lactate oxidation(GO:0019516)
0.1 1.6 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.1 2.9 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 1.2 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.1 0.9 GO:0034312 diol biosynthetic process(GO:0034312)
0.1 0.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 1.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 1.2 GO:0051013 microtubule severing(GO:0051013)
0.1 0.4 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 2.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.8 GO:0043457 regulation of cellular respiration(GO:0043457)
0.1 0.6 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.8 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 1.2 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.1 2.0 GO:0007520 myoblast fusion(GO:0007520)
0.1 1.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 5.3 GO:0006096 glycolytic process(GO:0006096)
0.1 0.2 GO:0071600 otic vesicle development(GO:0071599) otic vesicle morphogenesis(GO:0071600)
0.1 0.4 GO:0051661 maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684)
0.1 0.8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.9 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 0.6 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.1 0.6 GO:0046548 retinal rod cell development(GO:0046548)
0.1 4.0 GO:0001824 blastocyst development(GO:0001824)
0.1 3.1 GO:0048645 organ formation(GO:0048645)
0.1 0.2 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.1 0.6 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.1 0.3 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 1.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 3.8 GO:0050909 sensory perception of taste(GO:0050909)
0.1 1.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.9 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 2.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 1.6 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.5 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.4 GO:0048840 otolith development(GO:0048840)
0.1 1.5 GO:0097186 amelogenesis(GO:0097186)
0.1 0.3 GO:0070827 chromatin maintenance(GO:0070827)
0.1 0.7 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.1 1.7 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.1 0.6 GO:0051601 exocyst localization(GO:0051601)
0.1 0.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 0.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.7 GO:0048305 immunoglobulin secretion(GO:0048305)
0.1 0.1 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 0.4 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.1 0.7 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 1.9 GO:0014902 myotube differentiation(GO:0014902)
0.0 2.1 GO:0007338 single fertilization(GO:0007338)
0.0 1.5 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.7 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 1.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.0 0.1 GO:1900095 random inactivation of X chromosome(GO:0060816) regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0 0.3 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.4 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.0 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.2 GO:0007530 sex determination(GO:0007530)
0.0 0.2 GO:0033692 cellular polysaccharide biosynthetic process(GO:0033692)
0.0 0.2 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.7 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 2.8 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
0.0 0.5 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.1 GO:0070084 protein initiator methionine removal(GO:0070084)
0.0 0.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 6.8 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.8 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 0.0 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.1 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.0 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.8 GO:1903749 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.3 GO:0051782 negative regulation of cell division(GO:0051782)
0.0 0.0 GO:1903960 negative regulation of anion channel activity(GO:0010360) negative regulation of anion transmembrane transport(GO:1903960)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
9.3 65.4 GO:0005579 membrane attack complex(GO:0005579)
7.9 63.2 GO:0005577 fibrinogen complex(GO:0005577)
3.9 15.4 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
3.7 58.8 GO:0042612 MHC class I protein complex(GO:0042612)
3.2 12.9 GO:1990584 cardiac Troponin complex(GO:1990584)
3.1 12.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
2.7 18.9 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
2.5 12.7 GO:1990716 axonemal central apparatus(GO:1990716)
2.5 10.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
2.2 8.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
2.2 37.6 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
2.2 6.5 GO:0070821 tertiary granule membrane(GO:0070821)
2.2 19.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
2.1 39.7 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
2.1 231.3 GO:0072562 blood microparticle(GO:0072562)
2.0 20.3 GO:0045179 apical cortex(GO:0045179)
1.9 56.8 GO:0042588 zymogen granule(GO:0042588)
1.8 25.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
1.8 25.2 GO:0032982 myosin filament(GO:0032982)
1.8 23.2 GO:0046581 intercellular canaliculus(GO:0046581)
1.8 8.9 GO:0035061 interchromatin granule(GO:0035061)
1.8 8.8 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
1.7 5.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
1.7 6.8 GO:0019814 immunoglobulin complex(GO:0019814) B cell receptor complex(GO:0019815)
1.7 6.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
1.7 6.7 GO:0001405 presequence translocase-associated import motor(GO:0001405)
1.6 20.2 GO:0000801 central element(GO:0000801)
1.5 10.8 GO:0090543 Flemming body(GO:0090543)
1.5 4.6 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
1.5 9.1 GO:0036128 CatSper complex(GO:0036128)
1.3 4.0 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
1.3 9.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
1.3 3.8 GO:0032807 DNA ligase IV complex(GO:0032807)
1.3 8.8 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
1.2 8.7 GO:0005833 hemoglobin complex(GO:0005833)
1.2 8.4 GO:0097524 sperm plasma membrane(GO:0097524)
1.2 3.6 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
1.1 4.6 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
1.1 3.4 GO:0042627 chylomicron(GO:0042627)
1.1 7.9 GO:0044194 cytolytic granule(GO:0044194)
1.1 6.5 GO:0097209 epidermal lamellar body(GO:0097209)
1.1 5.4 GO:0002081 outer acrosomal membrane(GO:0002081)
1.0 17.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.9 14.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.9 1.9 GO:0043159 acrosomal matrix(GO:0043159)
0.9 8.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.9 8.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.8 3.3 GO:0097413 Lewy body(GO:0097413)
0.8 19.7 GO:0097225 sperm midpiece(GO:0097225)
0.8 8.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.8 6.3 GO:0002177 manchette(GO:0002177)
0.8 10.2 GO:0042599 lamellar body(GO:0042599)
0.8 12.5 GO:0031672 A band(GO:0031672)
0.8 4.6 GO:1990111 spermatoproteasome complex(GO:1990111)
0.7 18.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.7 2.8 GO:0030478 actin cap(GO:0030478)
0.7 2.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.7 2.0 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.7 13.9 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.7 11.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.7 4.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.7 44.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.6 2.6 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.6 4.5 GO:0051286 cell tip(GO:0051286)
0.6 1.9 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.6 3.8 GO:0060205 cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.6 15.7 GO:0001533 cornified envelope(GO:0001533)
0.6 11.2 GO:0005916 fascia adherens(GO:0005916)
0.6 12.9 GO:0031528 microvillus membrane(GO:0031528)
0.6 2.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.6 6.7 GO:0045180 basal cortex(GO:0045180)
0.6 1.8 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.6 2.3 GO:0044299 C-fiber(GO:0044299)
0.6 4.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.6 1.7 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.6 1.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.6 2.3 GO:0031091 platelet alpha granule(GO:0031091)
0.6 7.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.5 6.6 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.5 5.5 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.5 16.5 GO:0005771 multivesicular body(GO:0005771)
0.5 2.6 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.5 3.7 GO:0070449 elongin complex(GO:0070449)
0.5 9.6 GO:0033391 chromatoid body(GO:0033391)
0.5 1.5 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.5 2.0 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.5 4.4 GO:0032059 bleb(GO:0032059)
0.5 1.5 GO:0032437 cuticular plate(GO:0032437)
0.5 4.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.5 4.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.5 1.9 GO:0097512 cardiac myofibril(GO:0097512)
0.5 1.4 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.5 1.4 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.4 4.0 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.4 2.2 GO:0043203 axon hillock(GO:0043203)
0.4 2.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.4 3.9 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.4 4.4 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.4 2.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.4 7.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.4 2.0 GO:0005642 annulate lamellae(GO:0005642)
0.4 1.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.4 1.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.4 2.3 GO:0071438 invadopodium membrane(GO:0071438)
0.4 1.1 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.4 1.5 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.4 24.6 GO:0005811 lipid particle(GO:0005811)
0.4 2.5 GO:0097452 GAIT complex(GO:0097452)
0.4 1.4 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.3 40.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.3 455.8 GO:0005615 extracellular space(GO:0005615)
0.3 2.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.3 4.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.3 6.7 GO:0005922 connexon complex(GO:0005922)
0.3 2.9 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.3 0.6 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3 87.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.3 1.6 GO:0097361 CIA complex(GO:0097361)
0.3 1.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.3 8.9 GO:0035371 microtubule plus-end(GO:0035371)
0.3 39.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.3 26.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.3 5.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.3 2.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.3 1.1 GO:0097342 death-inducing signaling complex(GO:0031264) ripoptosome(GO:0097342)
0.3 13.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.3 1.6 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.3 5.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.3 6.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 1.5 GO:0001940 male pronucleus(GO:0001940)
0.2 2.0 GO:0000974 Prp19 complex(GO:0000974)
0.2 14.1 GO:0045178 basal part of cell(GO:0045178)
0.2 1.2 GO:0043256 laminin complex(GO:0043256)
0.2 3.0 GO:0070852 cell body fiber(GO:0070852)
0.2 1.8 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2 1.8 GO:0005921 gap junction(GO:0005921)
0.2 1.6 GO:0042788 polysomal ribosome(GO:0042788)
0.2 4.9 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.2 0.9 GO:0031417 NatC complex(GO:0031417)
0.2 1.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 0.8 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 13.2 GO:0045095 keratin filament(GO:0045095)
0.2 2.5 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.2 1.9 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 0.7 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 3.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.2 18.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.2 0.9 GO:0032389 MutLalpha complex(GO:0032389)
0.2 8.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 2.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.2 23.2 GO:0031674 I band(GO:0031674)
0.2 6.4 GO:0005902 microvillus(GO:0005902)
0.2 2.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 0.8 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 1.1 GO:0043202 lysosomal lumen(GO:0043202)
0.1 7.9 GO:0005643 nuclear pore(GO:0005643)
0.1 0.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 2.4 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.7 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 1.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 2.3 GO:0005839 proteasome core complex(GO:0005839)
0.1 0.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 2.0 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 1.5 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.9 GO:0034464 BBSome(GO:0034464)
0.1 3.1 GO:0016459 myosin complex(GO:0016459)
0.1 71.5 GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network(GO:0042175)
0.1 4.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 3.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 0.5 GO:0060091 kinocilium(GO:0060091)
0.1 0.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 1.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 2.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 3.1 GO:0005581 collagen trimer(GO:0005581)
0.1 0.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 3.9 GO:0015030 Cajal body(GO:0015030)
0.1 2.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 14.3 GO:0005667 transcription factor complex(GO:0005667)
0.1 3.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.8 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 1.9 GO:0005844 polysome(GO:0005844)
0.1 61.7 GO:0005739 mitochondrion(GO:0005739)
0.1 3.2 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.6 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 0.7 GO:0019028 viral capsid(GO:0019028)
0.0 1.0 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
11.8 59.0 GO:0005550 pheromone binding(GO:0005550)
10.0 30.0 GO:0098603 selenol Se-methyltransferase activity(GO:0098603)
6.5 19.4 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
6.4 38.6 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
6.2 18.6 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
5.4 32.3 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
5.2 31.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
5.1 20.4 GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294)
4.8 24.2 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
4.7 23.4 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
4.6 18.6 GO:0004771 sterol esterase activity(GO:0004771)
4.5 18.0 GO:0004967 glucagon receptor activity(GO:0004967)
4.4 13.1 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
4.4 17.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
4.3 12.9 GO:0030172 troponin C binding(GO:0030172)
4.3 29.8 GO:0035375 zymogen binding(GO:0035375)
4.1 12.4 GO:0031720 haptoglobin binding(GO:0031720)
4.0 31.9 GO:0003996 acyl-CoA ligase activity(GO:0003996)
4.0 15.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
4.0 11.9 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
3.9 11.8 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
3.9 15.4 GO:0019002 GMP binding(GO:0019002)
3.7 11.2 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
3.7 11.0 GO:0001847 opsonin receptor activity(GO:0001847)
3.7 11.0 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
3.6 10.9 GO:0004655 porphobilinogen synthase activity(GO:0004655)
3.6 14.2 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
3.5 17.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
3.4 13.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
3.3 13.3 GO:0042806 fucose binding(GO:0042806)
3.3 16.4 GO:0019770 IgG receptor activity(GO:0019770)
3.2 13.0 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
3.2 12.8 GO:0034618 arginine binding(GO:0034618)
3.2 9.6 GO:0052871 leukotriene-B4 20-monooxygenase activity(GO:0050051) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
3.0 18.1 GO:0004126 cytidine deaminase activity(GO:0004126)
3.0 9.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
3.0 86.8 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
2.9 8.8 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
2.9 20.5 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
2.9 11.7 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
2.8 22.4 GO:0051525 NFAT protein binding(GO:0051525)
2.8 44.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
2.8 30.7 GO:0001846 opsonin binding(GO:0001846)
2.7 19.2 GO:0016803 ether hydrolase activity(GO:0016803)
2.6 10.6 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
2.6 7.7 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
2.5 7.5 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
2.5 7.4 GO:0046980 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
2.5 7.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
2.4 9.6 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
2.3 14.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
2.3 16.2 GO:0048019 receptor antagonist activity(GO:0048019)
2.3 70.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
2.2 6.6 GO:0046977 TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
2.2 8.7 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
2.1 6.4 GO:0032810 sterol response element binding(GO:0032810)
2.1 8.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
2.1 8.3 GO:0004064 arylesterase activity(GO:0004064)
2.0 8.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
2.0 6.0 GO:0004370 glycerol kinase activity(GO:0004370)
2.0 8.0 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
2.0 8.0 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
2.0 9.9 GO:0004103 choline kinase activity(GO:0004103)
1.9 7.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
1.9 11.5 GO:0030881 beta-2-microglobulin binding(GO:0030881)
1.9 5.8 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
1.9 5.6 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
1.9 14.8 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
1.8 5.5 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
1.8 5.5 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
1.8 209.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
1.8 10.5 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
1.7 22.6 GO:0003796 lysozyme activity(GO:0003796)
1.7 17.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
1.7 1.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
1.7 5.1 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
1.7 8.4 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
1.6 8.2 GO:0070891 lipoteichoic acid binding(GO:0070891)
1.6 6.5 GO:0046790 virion binding(GO:0046790)
1.6 4.8 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
1.6 6.2 GO:0035514 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
1.5 4.6 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
1.5 6.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
1.5 4.5 GO:0001605 adrenomedullin receptor activity(GO:0001605)
1.5 14.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
1.4 4.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
1.4 14.1 GO:0019957 C-C chemokine binding(GO:0019957)
1.4 4.2 GO:0002058 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydrouracil dehydrogenase (NAD+) activity(GO:0004159) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
1.4 8.4 GO:0048039 ubiquinone binding(GO:0048039)
1.4 5.5 GO:0016019 peptidoglycan receptor activity(GO:0016019)
1.4 6.8 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
1.3 4.0 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
1.3 4.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
1.3 6.5 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
1.3 285.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
1.3 5.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
1.3 5.1 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
1.3 45.5 GO:0004364 glutathione transferase activity(GO:0004364)
1.2 7.4 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
1.2 3.7 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
1.2 3.7 GO:0015254 glycerol channel activity(GO:0015254)
1.2 3.6 GO:0070976 TIR domain binding(GO:0070976)
1.2 3.6 GO:0004946 bombesin receptor activity(GO:0004946)
1.2 10.8 GO:0019864 IgG binding(GO:0019864)
1.2 3.6 GO:0004104 acetylcholinesterase activity(GO:0003990) cholinesterase activity(GO:0004104)
1.2 34.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
1.2 5.9 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.2 3.5 GO:0004825 methionine-tRNA ligase activity(GO:0004825)
1.2 17.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
1.1 4.6 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
1.1 42.1 GO:0005044 scavenger receptor activity(GO:0005044)
1.1 32.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
1.1 5.6 GO:0005134 interleukin-2 receptor binding(GO:0005134)
1.1 3.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
1.1 3.2 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
1.1 4.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
1.0 5.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
1.0 5.2 GO:0004969 histamine receptor activity(GO:0004969)
1.0 2.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
1.0 15.4 GO:0005523 tropomyosin binding(GO:0005523)
1.0 3.1 GO:0048030 disaccharide binding(GO:0048030)
1.0 3.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
1.0 4.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
1.0 4.0 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
1.0 4.0 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
1.0 15.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
1.0 3.9 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
1.0 12.6 GO:0016208 AMP binding(GO:0016208)
1.0 5.8 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
1.0 7.7 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
1.0 10.5 GO:0004017 adenylate kinase activity(GO:0004017)
1.0 2.9 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
1.0 3.8 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.9 2.8 GO:0019959 interleukin-8 receptor activity(GO:0004918) interleukin-8 binding(GO:0019959)
0.9 20.8 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.9 12.2 GO:0097200 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.9 2.8 GO:0030350 iron-responsive element binding(GO:0030350)
0.9 4.7 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.9 2.8 GO:0003921 GMP synthase activity(GO:0003921) GMP synthase (glutamine-hydrolyzing) activity(GO:0003922)
0.9 4.6 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.9 6.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.9 12.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.9 7.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.9 2.7 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.9 9.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.9 2.7 GO:0005502 11-cis retinal binding(GO:0005502)
0.9 10.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.9 3.4 GO:0048408 epidermal growth factor binding(GO:0048408)
0.9 1.7 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.8 17.8 GO:0000146 microfilament motor activity(GO:0000146)
0.8 2.5 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.8 7.5 GO:0008097 5S rRNA binding(GO:0008097)
0.8 4.1 GO:0001155 TFIIIA-class transcription factor binding(GO:0001155)
0.8 7.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.8 4.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.8 21.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.8 1.6 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.8 11.9 GO:0051787 misfolded protein binding(GO:0051787)
0.8 1.6 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.8 3.2 GO:0047619 acylcarnitine hydrolase activity(GO:0047619)
0.8 3.9 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.8 5.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.8 9.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.8 7.0 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.8 6.9 GO:0030957 Tat protein binding(GO:0030957)
0.7 3.7 GO:0050733 RS domain binding(GO:0050733)
0.7 8.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.7 3.7 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.7 8.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.7 15.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.7 5.7 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.7 2.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.7 6.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.7 9.7 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.7 9.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.7 8.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.7 4.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.7 3.4 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.7 2.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.7 6.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.7 1.3 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.7 2.0 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.7 11.8 GO:0042288 MHC class I protein binding(GO:0042288)
0.7 5.2 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.6 10.9 GO:0070628 proteasome binding(GO:0070628)
0.6 8.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.6 2.5 GO:0000403 Y-form DNA binding(GO:0000403)
0.6 3.7 GO:0004985 opioid receptor activity(GO:0004985)
0.6 1.8 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.6 4.2 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.6 5.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.6 10.1 GO:0008199 ferric iron binding(GO:0008199)
0.6 1.8 GO:0051185 coenzyme transporter activity(GO:0051185)
0.6 1.8 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.6 18.5 GO:0042605 peptide antigen binding(GO:0042605)
0.6 9.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.6 2.9 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.6 5.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.6 3.9 GO:0070492 oligosaccharide binding(GO:0070492)
0.6 4.4 GO:0016421 CoA carboxylase activity(GO:0016421)
0.6 3.3 GO:0004568 chitinase activity(GO:0004568)
0.5 4.9 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.5 8.1 GO:0001618 virus receptor activity(GO:0001618)
0.5 1.6 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.5 11.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.5 3.2 GO:0036374 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.5 1.6 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.5 1.6 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.5 5.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.5 10.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.5 1.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.5 2.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.5 2.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.5 5.7 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.5 4.6 GO:0035613 RNA stem-loop binding(GO:0035613)
0.5 2.5 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.5 13.3 GO:0051393 alpha-actinin binding(GO:0051393)
0.5 5.8 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.5 15.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.5 1.4 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.5 5.1 GO:0017166 vinculin binding(GO:0017166)
0.5 2.3 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.5 3.2 GO:0043559 insulin binding(GO:0043559)
0.5 5.5 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.5 1.4 GO:0097677 STAT family protein binding(GO:0097677)
0.5 5.4 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.4 1.3 GO:0032190 acrosin binding(GO:0032190)
0.4 2.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.4 1.7 GO:0035473 lipase binding(GO:0035473)
0.4 3.5 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.4 2.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.4 13.1 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.4 10.9 GO:0004016 adenylate cyclase activity(GO:0004016)
0.4 111.6 GO:0030246 carbohydrate binding(GO:0030246)
0.4 2.5 GO:0031404 chloride ion binding(GO:0031404)
0.4 1.7 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.4 1.2 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.4 4.4 GO:0015643 toxic substance binding(GO:0015643)
0.4 3.9 GO:0002162 dystroglycan binding(GO:0002162)
0.4 8.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.4 11.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.4 2.3 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.4 1.9 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.4 6.1 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.4 2.9 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.4 7.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.4 1.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.4 8.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4 10.8 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.4 3.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.4 1.4 GO:0070568 guanylyltransferase activity(GO:0070568)
0.3 1.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.3 2.8 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3 2.7 GO:0008494 translation activator activity(GO:0008494)
0.3 7.0 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.3 5.6 GO:0001594 trace-amine receptor activity(GO:0001594)
0.3 1.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.3 4.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.3 1.3 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.3 1.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.3 1.0 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.3 10.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 7.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3 1.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.3 1.5 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.3 1.2 GO:0008242 omega peptidase activity(GO:0008242)
0.3 3.7 GO:0016805 dipeptidase activity(GO:0016805)
0.3 0.9 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.3 0.6 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.3 2.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.3 0.9 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.3 2.0 GO:0045340 mercury ion binding(GO:0045340)
0.3 1.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.3 1.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.3 1.4 GO:0043515 kinetochore binding(GO:0043515)
0.3 1.9 GO:0008320 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)
0.3 1.9 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.3 0.8 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.3 0.8 GO:0046911 metal chelating activity(GO:0046911)
0.3 2.4 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.3 1.8 GO:0016918 retinal binding(GO:0016918)
0.3 1.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.3 1.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.3 2.8 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 1.5 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.2 1.0 GO:0050692 DBD domain binding(GO:0050692)
0.2 1.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 100.4 GO:0005549 odorant binding(GO:0005549)
0.2 10.8 GO:0005507 copper ion binding(GO:0005507)
0.2 4.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 14.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 2.1 GO:0001054 RNA polymerase I activity(GO:0001054)
0.2 207.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 0.9 GO:0070052 collagen V binding(GO:0070052)
0.2 1.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 3.4 GO:0017127 cholesterol transporter activity(GO:0017127)
0.2 8.4 GO:0003823 antigen binding(GO:0003823)
0.2 1.7 GO:0008172 S-methyltransferase activity(GO:0008172)
0.2 3.0 GO:0008236 serine-type peptidase activity(GO:0008236)
0.2 2.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 4.8 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.2 1.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.2 20.9 GO:0015405 primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405)
0.2 4.3 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.2 1.0 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 3.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 3.5 GO:0008301 DNA binding, bending(GO:0008301)
0.2 1.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 3.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 0.9 GO:0031849 olfactory receptor binding(GO:0031849)
0.2 6.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 4.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 0.9 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 1.4 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) peptidase activator activity involved in apoptotic process(GO:0016505)
0.2 1.5 GO:0008198 ferrous iron binding(GO:0008198)
0.2 4.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 2.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 1.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 40.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 5.2 GO:0030332 cyclin binding(GO:0030332)
0.2 3.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 4.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 4.7 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 0.5 GO:0051990 (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.2 1.5 GO:0004180 carboxypeptidase activity(GO:0004180)
0.2 4.2 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.2 2.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 2.7 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 1.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 4.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 1.1 GO:0070513 death domain binding(GO:0070513)
0.1 1.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.7 GO:0019956 chemokine binding(GO:0019956)
0.1 0.7 GO:0008061 chitin binding(GO:0008061)
0.1 1.2 GO:0035497 cAMP response element binding(GO:0035497)
0.1 4.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.9 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.6 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 1.3 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.1 0.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 2.6 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 2.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 4.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 3.4 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 1.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 1.1 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 5.9 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 6.0 GO:0051087 chaperone binding(GO:0051087)
0.1 0.7 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 1.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 1.7 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.6 GO:0048018 receptor agonist activity(GO:0048018)
0.1 1.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 3.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 11.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.1 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 1.5 GO:0005521 lamin binding(GO:0005521)
0.1 4.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.7 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.4 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846) diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 7.1 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.1 1.5 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.5 GO:0000182 rDNA binding(GO:0000182)
0.1 7.2 GO:0001047 core promoter binding(GO:0001047)
0.1 0.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.9 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.1 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.5 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 1.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 2.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.4 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.8 GO:0004540 ribonuclease activity(GO:0004540)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 29.9 ST JAK STAT PATHWAY Jak-STAT Pathway
2.5 77.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
1.4 6.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
1.3 13.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
1.2 64.0 PID HNF3A PATHWAY FOXA1 transcription factor network
1.2 280.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.9 32.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.7 21.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.7 9.9 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.6 23.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.6 9.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.6 6.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.6 19.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.6 6.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.5 5.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.5 10.7 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.5 21.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.4 12.8 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.4 6.0 PID IL1 PATHWAY IL1-mediated signaling events
0.4 7.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.4 7.9 PID TRAIL PATHWAY TRAIL signaling pathway
0.4 9.8 ST ADRENERGIC Adrenergic Pathway
0.4 4.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 9.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 15.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.3 4.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.3 8.0 PID CONE PATHWAY Visual signal transduction: Cones
0.3 2.5 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.3 14.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 3.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3 2.7 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.3 9.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.3 3.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.3 2.5 PID FAS PATHWAY FAS (CD95) signaling pathway
0.2 37.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 2.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 48.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 7.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 7.6 PID BCR 5PATHWAY BCR signaling pathway
0.2 3.8 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.2 2.8 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.2 1.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2 5.6 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.2 10.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 7.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.2 6.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 18.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 0.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 2.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.2 1.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.2 1.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 1.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 0.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 2.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 6.8 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 4.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 3.6 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 4.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 3.8 PID SHP2 PATHWAY SHP2 signaling
0.1 1.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.1 0.9 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 4.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 0.4 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 0.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 0.7 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 1.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 1.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 3.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 2.5 PID P53 REGULATION PATHWAY p53 pathway
0.1 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 1.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 0.7 PID AURORA A PATHWAY Aurora A signaling
0.0 0.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.7 PID BMP PATHWAY BMP receptor signaling
0.0 1.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 75.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
4.0 111.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
3.9 50.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
3.6 10.9 REACTOME XENOBIOTICS Genes involved in Xenobiotics
3.4 71.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
2.9 14.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
2.9 55.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
2.6 38.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
2.4 21.7 REACTOME INTERFERON SIGNALING Genes involved in Interferon Signaling
2.4 40.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
2.4 21.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
2.2 39.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
1.7 107.9 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
1.7 49.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
1.6 22.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
1.4 7.2 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
1.4 53.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
1.3 4.0 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
1.3 11.7 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
1.3 62.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
1.3 18.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
1.2 9.9 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
1.2 20.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
1.1 5.7 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
1.1 16.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
1.1 15.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.0 2.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
1.0 47.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.9 7.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.9 10.9 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.9 13.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.9 11.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.9 12.8 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.7 6.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.7 1.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.6 8.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.6 7.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.6 8.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.6 6.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.5 10.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.5 5.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.5 4.1 REACTOME OPSINS Genes involved in Opsins
0.5 6.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.5 9.9 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.5 7.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.4 5.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.4 15.6 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.4 4.9 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.4 3.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.4 1.7 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.4 3.9 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.4 73.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.4 17.0 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.4 5.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.4 4.0 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.4 6.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.4 6.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4 6.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.4 2.6 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.4 7.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.4 4.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.4 2.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.4 6.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.3 7.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.3 3.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.3 9.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.3 3.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 18.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.3 11.5 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.3 10.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.3 25.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.3 1.8 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.3 2.8 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.2 7.6 REACTOME KINESINS Genes involved in Kinesins
0.2 10.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 1.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 0.9 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.2 2.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 1.5 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.2 9.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.2 3.0 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2 2.3 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.2 4.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 3.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 12.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 2.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 1.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.2 2.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 4.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 1.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 4.1 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.2 5.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 3.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 10.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 0.5 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events
0.1 14.2 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.1 3.0 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 3.0 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.1 4.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 0.5 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.1 2.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 2.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 2.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 1.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.6 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.1 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 0.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 9.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.0 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants