GSE53960: rat RNA-Seq transcriptomic Bodymap

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
Stat2 Links NCBI RGD Ensembl	ENSRNOG00000031081	signal transducer and activator of transcription 2

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Stat2	rn6_v1_chr7_+_2691369_2691369	0.74	2.0e-56	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr5_-_58198782 Show fit	110.28	ENSRNOT00000023951	Ccl21 Links NCBI RGD Ensembl Show fit	C-C motif chemokine ligand 21
chr15_+_18710492 Show fit	101.52	ENSRNOT00000012532	Dnase1l3 Links NCBI RGD Ensembl Show fit	deoxyribonuclease 1-like 3
chr20_+_3990820 Show fit	86.58	ENSRNOT00000000528	Psmb8 Links NCBI RGD Ensembl Show fit	proteasome subunit beta 8
chr10_-_70744315 Show fit	75.67	ENSRNOT00000014865	Ccl5 Links NCBI RGD Ensembl Show fit	C-C motif chemokine ligand 5
chr4_+_153805993 Show fit	72.28	ENSRNOT00000056174	Usp18 Links NCBI RGD Ensembl Show fit	ubiquitin specific peptidase 18
chr3_-_171286413 Show fit	71.44	ENSRNOT00000008365 ENSRNOT00000081036	Zbp1 Links NCBI RGD Ensembl Show fit	Z-DNA binding protein 1
chr10_-_70342411 Show fit	70.88	ENSRNOT00000076269 ENSRNOT00000076477	Slfn13 Links NCBI RGD Ensembl Show fit	schlafen family member 13
chr13_+_89385859 Show fit	69.12	ENSRNOT00000047434	Fcgr3a Links NCBI RGD Ensembl Show fit	Fc fragment of IgG receptor IIIa
chr5_-_58183017 Show fit	68.40	ENSRNOT00000020982	Ccl19 Links NCBI RGD Ensembl Show fit	C-C motif chemokine ligand 19
chr20_-_27682861 Show fit	66.48	ENSRNOT00000057317	Fam26f Links NCBI RGD Ensembl Show fit	family with sequence similarity 26, member F
chr3_-_176744377 Show fit	65.63	ENSRNOT00000017787	Helz2 Links NCBI RGD Ensembl Show fit	helicase with zinc finger 2, transcriptional coactivator
chr4_-_163403653 Show fit	64.73	ENSRNOT00000088151	Klrk1 Links NCBI RGD Ensembl Show fit	killer cell lectin like receptor K1
chrX_-_105390580 Show fit	64.45	ENSRNOT00000077547	Btk Links NCBI RGD Ensembl Show fit	Bruton tyrosine kinase
chr13_+_89386023 Show fit	63.05	ENSRNOT00000086223	Fcgr3a Links NCBI RGD Ensembl Show fit	Fc fragment of IgG receptor IIIa
chr1_-_214252456 Show fit	62.26	ENSRNOT00000023504	Irf7 Links NCBI RGD Ensembl Show fit	interferon regulatory factor 7
chr20_+_3979035 Show fit	58.48	ENSRNOT00000000529	Tap1 Links NCBI RGD Ensembl Show fit	transporter 1, ATP binding cassette subfamily B member
chr2_+_209097927 Show fit	55.74	ENSRNOT00000023807	Dennd2d Links NCBI RGD Ensembl Show fit	DENN domain containing 2D
chr1_+_215628785 Show fit	55.15	ENSRNOT00000054864	Lsp1 Links NCBI RGD Ensembl Show fit	lymphocyte-specific protein 1
chr4_+_162493908 Show fit	55.13	ENSRNOT00000072064	Clec2d Links NCBI RGD Ensembl Show fit	C-type lectin domain family 2, member D
chr12_+_41200718 Show fit	54.63	ENSRNOT00000038426 ENSRNOT00000048450 ENSRNOT00000067176	Oas1a Links NCBI RGD Ensembl Show fit	2'-5' oligoadenylate synthetase 1A
chr18_+_55576239 Show fit	52.95	ENSRNOT00000050063	LOC100910979 Links NCBI RGD Ensembl Show fit	interferon-inducible GTPase 1-like
chr9_-_92616165 Show fit	52.38	ENSRNOT00000056995	Sp110 Links NCBI RGD Ensembl Show fit	SP110 nuclear body protein
chr1_+_279867034 Show fit	50.85	ENSRNOT00000024164	Pnliprp1 Links NCBI RGD Ensembl Show fit	pancreatic lipase-related protein 1
chr2_+_248178389 Show fit	50.45	ENSRNOT00000037339	Gbp5 Links NCBI RGD Ensembl Show fit	guanylate binding protein 5
chr20_-_3793985 Show fit	49.17	ENSRNOT00000049540 ENSRNOT00000086293	RT1-CE16 Links NCBI RGD Ensembl Show fit	RT1 class I, locus CE16
chr2_-_190100276 Show fit	48.32	ENSRNOT00000015351	S100a9 Links NCBI RGD Ensembl Show fit	S100 calcium binding protein A9
chr11_-_37914983 Show fit	47.63	ENSRNOT00000039876	Mx1 Links NCBI RGD Ensembl Show fit	myxovirus (influenza virus) resistance 1
chr16_-_19942343 Show fit	45.78	ENSRNOT00000087162 ENSRNOT00000091906	Bst2 Links NCBI RGD Ensembl Show fit	bone marrow stromal cell antigen 2
chr20_+_4855829 Show fit	45.63	ENSRNOT00000001110	LOC103694380 Links NCBI RGD Ensembl Show fit	tumor necrosis factor-like
chr12_+_41341417 Show fit	45.54	ENSRNOT00000072024 ENSRNOT00000091460	Oas2 Links NCBI RGD Ensembl Show fit	2'-5' oligoadenylate synthetase 2
chr13_+_93684437 Show fit	44.81	ENSRNOT00000005005	Kmo Links NCBI RGD Ensembl Show fit	kynurenine 3-monooxygenase
chr4_+_102351036 Show fit	44.40	ENSRNOT00000079277	AABR07060994.1 Links NCBI RGD Ensembl Show fit
chrX_+_54390733 Show fit	43.42	ENSRNOT00000004977	RGD1565785 Links NCBI RGD Ensembl Show fit	similar to chromosome X open reading frame 21
chr20_-_3978845 Show fit	43.09	ENSRNOT00000000532	Psmb9 Links NCBI RGD Ensembl Show fit	proteasome subunit beta 9
chr1_+_169433539 Show fit	42.69	ENSRNOT00000055210	Trim34 Links NCBI RGD Ensembl Show fit	tripartite motif-containing 34
chr10_+_76343847 Show fit	42.48	ENSRNOT00000055674	Trim25 Links NCBI RGD Ensembl Show fit	tripartite motif-containing 25
chr6_+_127327959 Show fit	41.98	ENSRNOT00000012296	Ifi27 Links NCBI RGD Ensembl Show fit	interferon, alpha-inducible protein 27
chr10_-_66229311 Show fit	41.87	ENSRNOT00000016897	Lgals5 Links NCBI RGD Ensembl Show fit	lectin, galactose binding, soluble 5
chr10_+_43613931 Show fit	41.66	ENSRNOT00000039335	Igtp Links NCBI RGD Ensembl Show fit	interferon gamma induced GTPase
chr11_+_38035611 Show fit	41.37	ENSRNOT00000087603 ENSRNOT00000002695	Mx2 Links NCBI RGD Ensembl Show fit	MX dynamin like GTPase 2
chr10_-_5253336 Show fit	41.31	ENSRNOT00000085310	Ciita Links NCBI RGD Ensembl Show fit	class II, major histocompatibility complex, transactivator
chr10_+_94944436 Show fit	40.94	ENSRNOT00000078968	Milr1 Links NCBI RGD Ensembl Show fit	mast cell immunoglobulin-like receptor 1
chr4_+_67165883 Show fit	40.71	ENSRNOT00000012280	Rab19 Links NCBI RGD Ensembl Show fit	RAB19, member RAS oncogene family
chr11_+_67757928 Show fit	40.39	ENSRNOT00000039215	Dtx3l Links NCBI RGD Ensembl Show fit	deltex E3 ubiquitin ligase 3L
chr16_-_85306366 Show fit	40.23	ENSRNOT00000089650	Tnfsf13b Links NCBI RGD Ensembl Show fit	tumor necrosis factor superfamily member 13b
chr11_+_68105369 Show fit	40.11	ENSRNOT00000046888	Parp14 Links NCBI RGD Ensembl Show fit	poly (ADP-ribose) polymerase family, member 14
chr10_+_31880918 Show fit	39.66	ENSRNOT00000059448	Timd4 Links NCBI RGD Ensembl Show fit	T-cell immunoglobulin and mucin domain containing 4
chr7_-_117300662 Show fit	39.36	ENSRNOT00000006376	Parp10 Links NCBI RGD Ensembl Show fit	poly (ADP-ribose) polymerase family, member 10
chr1_+_252906234 Show fit	39.14	ENSRNOT00000031025	Ifit3 Links NCBI RGD Ensembl Show fit	interferon-induced protein with tetratricopeptide repeats 3
chr17_+_9236249 Show fit	38.98	ENSRNOT00000015878	Tifab Links NCBI RGD Ensembl Show fit	TIFA inhibitor
chr15_+_34282936 Show fit	38.83	ENSRNOT00000026364	Irf9 Links NCBI RGD Ensembl Show fit	interferon regulatory factor 9
chr10_-_107424710 Show fit	37.88	ENSRNOT00000004320	Lgals3bp Links NCBI RGD Ensembl Show fit	galectin 3 binding protein
chr8_+_116754178 Show fit	37.61	ENSRNOT00000068295 ENSRNOT00000084429	Uba7 Links NCBI RGD Ensembl Show fit	ubiquitin-like modifier activating enzyme 7
chr10_-_88163712 Show fit	36.95	ENSRNOT00000005382 ENSRNOT00000084493	Krt17 Links NCBI RGD Ensembl Show fit	keratin 17
chr2_-_243224883 Show fit	36.16	ENSRNOT00000014139	Dapp1 Links NCBI RGD Ensembl Show fit	dual adaptor of phosphotyrosine and 3-phosphoinositides 1
chr15_+_60084918 Show fit	36.10	ENSRNOT00000012632	Epsti1 Links NCBI RGD Ensembl Show fit	epithelial stromal interaction 1
chr20_+_3146856 Show fit	35.89	ENSRNOT00000050159	RT1-N2 Links NCBI RGD Ensembl Show fit	RT1 class Ib, locus N2
chr11_+_67082193 Show fit	35.61	ENSRNOT00000003129	Cd86 Links NCBI RGD Ensembl Show fit	CD86 molecule
chr1_+_221538104 Show fit	35.40	ENSRNOT00000028527	Batf2 Links NCBI RGD Ensembl Show fit	basic leucine zipper ATF-like transcription factor 2
chr8_-_63034226 Show fit	35.09	ENSRNOT00000043434	Pml Links NCBI RGD Ensembl Show fit	promyelocytic leukemia
chr5_-_173626248 Show fit	34.80	ENSRNOT00000039263	Isg15 Links NCBI RGD Ensembl Show fit	ISG15 ubiquitin-like modifier
chr13_-_83917001 Show fit	34.41	ENSRNOT00000004387 ENSRNOT00000082422	Rcsd1 Links NCBI RGD Ensembl Show fit	RCSD domain containing 1
chr3_-_37480984 Show fit	34.09	ENSRNOT00000030373	Nmi Links NCBI RGD Ensembl Show fit	N-myc (and STAT) interactor
chr12_+_41155497 Show fit	33.17	ENSRNOT00000041741	Oas1g Links NCBI RGD Ensembl Show fit	2'-5' oligoadenylate synthetase 1G
chr16_-_85305782 Show fit	32.81	ENSRNOT00000067511 ENSRNOT00000076737	Tnfsf13b Links NCBI RGD Ensembl Show fit	tumor necrosis factor superfamily member 13b
chr1_-_252922486 Show fit	32.58	ENSRNOT00000076802	Ifit1bl Links NCBI RGD Ensembl Show fit	interferon-induced protein with tetratricopeptide repeats 1B-like
chr2_-_256915563 Show fit	32.28	ENSRNOT00000084873 ENSRNOT00000029990	Ifi44 Links NCBI RGD Ensembl Show fit	interferon-induced protein 44
chr17_-_32661865 Show fit	31.99	ENSRNOT00000022194	Serpinb9 Links NCBI RGD Ensembl Show fit	serpin family B member 9
chr10_-_4257868 Show fit	31.59	ENSRNOT00000035886	Tnfrsf17 Links NCBI RGD Ensembl Show fit	TNF receptor superfamily member 17
chr1_-_167708685 Show fit	31.20	ENSRNOT00000092857 ENSRNOT00000024992	Trim21 Links NCBI RGD Ensembl Show fit	tripartite motif-containing 21
chr12_+_42343123 Show fit	30.66	ENSRNOT00000043279	Oas1i Links NCBI RGD Ensembl Show fit	2 ' -5 ' oligoadenylate synthetase 1I
chr20_-_4542073 Show fit	30.50	ENSRNOT00000000477	Cfb Links NCBI RGD Ensembl Show fit	complement factor B
chr3_-_72171078 Show fit	30.05	ENSRNOT00000009817	Serping1 Links NCBI RGD Ensembl Show fit	serpin family G member 1
chr15_+_34256071 Show fit	30.02	ENSRNOT00000025887	Psme1 Links NCBI RGD Ensembl Show fit	proteasome activator subunit 1
chr10_+_89358376 Show fit	29.15	ENSRNOT00000028067	Ifi35 Links NCBI RGD Ensembl Show fit	interferon-induced protein 35
chr3_+_161519743 Show fit	28.31	ENSRNOT00000055148	Cd40 Links NCBI RGD Ensembl Show fit	CD40 molecule
chr20_-_3166569 Show fit	28.18	ENSRNOT00000091390	AABR07044362.1 Links NCBI RGD Ensembl Show fit
chr11_+_38035450 Show fit	28.07	ENSRNOT00000083067	Mx2 Links NCBI RGD Ensembl Show fit	MX dynamin like GTPase 2
chr9_-_26932201 Show fit	27.94	ENSRNOT00000017081	Mcm3 Links NCBI RGD Ensembl Show fit	minichromosome maintenance complex component 3
chr10_+_104377748 Show fit	27.83	ENSRNOT00000080714	Llgl2 Links NCBI RGD Ensembl Show fit	LLGL2, scribble cell polarity complex component
chr10_+_58860940 Show fit	27.51	ENSRNOT00000056551 ENSRNOT00000074523	XAF1 Links NCBI RGD Ensembl Show fit	XIAP associated factor-1
chr4_+_179398621 Show fit	26.69	ENSRNOT00000049474 ENSRNOT00000067506	Lrmp Links NCBI RGD Ensembl Show fit	lymphoid-restricted membrane protein
chr10_+_108527740 Show fit	26.58	ENSRNOT00000044983	Rnf213 Links NCBI RGD Ensembl Show fit	ring finger protein 213
chr15_+_36809361 Show fit	26.37	ENSRNOT00000076667	Parp4 Links NCBI RGD Ensembl Show fit	poly (ADP-ribose) polymerase family, member 4
chr1_-_224974203 Show fit	25.85	ENSRNOT00000065694	Tmem179b Links NCBI RGD Ensembl Show fit	transmembrane protein 179B
chr4_-_66062089 Show fit	25.81	ENSRNOT00000018782	Zc3hav1 Links NCBI RGD Ensembl Show fit	zinc finger CCCH-type containing, antiviral 1
chr10_+_64737022 Show fit	25.68	ENSRNOT00000017071 ENSRNOT00000093232 ENSRNOT00000017042 ENSRNOT00000093244	Lgals9 Links NCBI RGD Ensembl Show fit	galectin 9
chr11_-_14304603 Show fit	25.66	ENSRNOT00000040202 ENSRNOT00000082143	Samsn1 Links NCBI RGD Ensembl Show fit	SAM domain, SH3 domain and nuclear localization signals, 1
chr20_+_3167079 Show fit	25.38	ENSRNOT00000001035	RT1-N3 Links NCBI RGD Ensembl Show fit	RT1 class Ib, locus N3
chr14_+_17210733 Show fit	25.35	ENSRNOT00000003075	Cxcl10 Links NCBI RGD Ensembl Show fit	C-X-C motif chemokine ligand 10
chr9_-_54351339 Show fit	25.30	ENSRNOT00000080522	Stat1 Links NCBI RGD Ensembl Show fit	signal transducer and activator of transcription 1
chr10_-_57064600 Show fit	25.00	ENSRNOT00000032926	Cxcl16 Links NCBI RGD Ensembl Show fit	C-X-C motif chemokine ligand 16
chr4_-_21920651 Show fit	24.71	ENSRNOT00000066211	Tmem243 Links NCBI RGD Ensembl Show fit	transmembrane protein 243
chr7_+_11878943 Show fit	24.37	ENSRNOT00000025634	Mob3a Links NCBI RGD Ensembl Show fit	MOB kinase activator 3A
chr10_+_90376933 Show fit	24.29	ENSRNOT00000028557	Grn Links NCBI RGD Ensembl Show fit	granulin precursor
chr8_-_85803433 Show fit	24.13	ENSRNOT00000081544 ENSRNOT00000073286	Mb21d1 Links NCBI RGD Ensembl Show fit	Mab-21 domain containing 1
chr20_-_5476193 Show fit	23.66	ENSRNOT00000044975	Tapbp Links NCBI RGD Ensembl Show fit	TAP binding protein
chr2_+_248276709 Show fit	23.21	ENSRNOT00000068683	Gbp2 Links NCBI RGD Ensembl Show fit	guanylate binding protein 2
chr5_+_113725717 Show fit	23.02	ENSRNOT00000032248	Tek Links NCBI RGD Ensembl Show fit	TEK receptor tyrosine kinase
chr17_-_43640387 Show fit	22.32	ENSRNOT00000087731	Hist1h1c Links NCBI RGD Ensembl Show fit	histone cluster 1 H1 family member c
chr10_-_34221928 Show fit	22.24	ENSRNOT00000045545	Irgm Links NCBI RGD Ensembl Show fit	immunity-related GTPase M
chr10_+_90377103 Show fit	22.03	ENSRNOT00000040472	Grn Links NCBI RGD Ensembl Show fit	granulin precursor
chr3_-_48604097 Show fit	21.08	ENSRNOT00000009620	Ifih1 Links NCBI RGD Ensembl Show fit	interferon induced with helicase C domain 1
chr10_-_110431792 Show fit	20.11	ENSRNOT00000054922	LOC619574 Links NCBI RGD Ensembl Show fit	hypothetical protein LOC619574
chr20_+_3269284 Show fit	19.92	ENSRNOT00000089044	RT1-T24-1 Links NCBI RGD Ensembl Show fit	RT1 class I, locus T24, gene 1
chr5_-_62153762 Show fit	19.40	ENSRNOT00000066001 ENSRNOT00000086962	Trim14 Links NCBI RGD Ensembl Show fit	tripartite motif-containing 14
chr20_+_3242470 Show fit	19.26	ENSRNOT00000078110 ENSRNOT00000041502	RT1-T24-2 Links NCBI RGD Ensembl Show fit RT1-T24-1 Links NCBI RGD Ensembl Show fit	RT1 class I, locus T24, gene 2 RT1 class I, locus T24, gene 1
chr19_-_55367353 Show fit	19.25	ENSRNOT00000091139	Piezo1 Links NCBI RGD Ensembl Show fit	piezo-type mechanosensitive ion channel component 1
chr17_+_53956203 Show fit	19.21	ENSRNOT00000022483	Ggps1 Links NCBI RGD Ensembl Show fit	geranylgeranyl diphosphate synthase 1
chr13_+_99220510 Show fit	19.17	ENSRNOT00000004519	Tmem63a Links NCBI RGD Ensembl Show fit	transmembrane protein 63a
chr7_-_140600818 Show fit	18.30	ENSRNOT00000082375	Lmbr1l Links NCBI RGD Ensembl Show fit	limb development membrane protein 1-like
chr10_-_88611105 Show fit	18.26	ENSRNOT00000024718	Dhx58 Links NCBI RGD Ensembl Show fit	DEXH-box helicase 58
chr1_+_100832324 Show fit	18.08	ENSRNOT00000056364	Il4i1 Links NCBI RGD Ensembl Show fit	interleukin 4 induced 1
chr15_+_49010492 Show fit	17.92	ENSRNOT00000024527	Nuggc Links NCBI RGD Ensembl Show fit	nuclear GTPase, germinal center associated
chr1_+_247562202 Show fit	17.54	ENSRNOT00000021614	Pdcd1lg2 Links NCBI RGD Ensembl Show fit	programmed cell death 1 ligand 2
chr10_-_16046033 Show fit	17.14	ENSRNOT00000089460	Cpeb4 Links NCBI RGD Ensembl Show fit	cytoplasmic polyadenylation element binding protein 4
chr5_+_117586103 Show fit	16.89	ENSRNOT00000084640	Usp1 Links NCBI RGD Ensembl Show fit	ubiquitin specific peptidase 1
chr12_-_47456894 Show fit	16.81	ENSRNOT00000001570	Oasl Links NCBI RGD Ensembl Show fit	2'-5'-oligoadenylate synthetase-like
chr4_-_66899914 Show fit	16.74	ENSRNOT00000011481	Parp12 Links NCBI RGD Ensembl Show fit	poly (ADP-ribose) polymerase family, member 12
chr4_-_157743199 Show fit	16.58	ENSRNOT00000038178	Tapbpl Links NCBI RGD Ensembl Show fit	TAP binding protein-like
chr18_+_55685613 Show fit	16.41	ENSRNOT00000040116	MGC105567 Links NCBI RGD Ensembl Show fit	similar to cDNA sequence BC023105
chr1_+_166125474 Show fit	16.23	ENSRNOT00000091822	Fchsd2 Links NCBI RGD Ensembl Show fit	FCH and double SH3 domains 2
chr4_-_81241152 Show fit	16.08	ENSRNOT00000015325 ENSRNOT00000015152	Hnrnpa2b1 Links NCBI RGD Ensembl Show fit	heterogeneous nuclear ribonucleoprotein A2/B1
chr2_-_210550490 Show fit	16.01	ENSRNOT00000081835 ENSRNOT00000025222 ENSRNOT00000086403	Csf1 Links NCBI RGD Ensembl Show fit	colony stimulating factor 1
chr3_+_114087287 Show fit	15.89	ENSRNOT00000023017	B2m Links NCBI RGD Ensembl Show fit	beta-2 microglobulin
chr6_+_135866739 Show fit	15.88	ENSRNOT00000013460	Exoc3l4 Links NCBI RGD Ensembl Show fit	exocyst complex component 3-like 4
chr1_-_53520788 Show fit	15.24	ENSRNOT00000060121	Gpr31 Links NCBI RGD Ensembl Show fit	G protein-coupled receptor 31
chr7_-_36000906 Show fit	14.97	ENSRNOT00000011178	Plxnc1 Links NCBI RGD Ensembl Show fit	plexin C1
chr1_+_277190964 Show fit	14.65	ENSRNOT00000080511	Casp7 Links NCBI RGD Ensembl Show fit	caspase 7
chr1_-_167093560 Show fit	14.64	ENSRNOT00000027301	Il18bp Links NCBI RGD Ensembl Show fit	interleukin 18 binding protein
chr4_+_62380914 Show fit	14.47	ENSRNOT00000029845	Tmem140 Links NCBI RGD Ensembl Show fit	transmembrane protein 140
chrX_+_11648989 Show fit	14.36	ENSRNOT00000041003	Bcor Links NCBI RGD Ensembl Show fit	BCL6 co-repressor
chr5_-_56536772 Show fit	14.22	ENSRNOT00000060765	Ddx58 Links NCBI RGD Ensembl Show fit	DEXD/H-box helicase 58
chr10_-_35175647 Show fit	14.10	ENSRNOT00000078960	Cnot6 Links NCBI RGD Ensembl Show fit	CCR4-NOT transcription complex, subunit 6
chr5_+_157423213 Show fit	13.86	ENSRNOT00000023431	Tmco4 Links NCBI RGD Ensembl Show fit	transmembrane and coiled-coil domains 4
chr16_+_50111306 Show fit	12.84	ENSRNOT00000019302	Cyp4v3 Links NCBI RGD Ensembl Show fit	cytochrome P450, family 4, subfamily v, polypeptide 3
chr4_-_120408232 Show fit	12.78	ENSRNOT00000073269	LOC100911337 Links NCBI RGD Ensembl Show fit	40S ribosomal protein S25-like
chr6_+_57396220 Show fit	12.46	ENSRNOT00000044779	RGD1563613 Links NCBI RGD Ensembl Show fit	similar to 40S ribosomal protein S25
chr7_+_2691369 Show fit	12.36	ENSRNOT00000049536	Stat2 Links NCBI RGD Ensembl Show fit	signal transducer and activator of transcription 2
chr6_+_8669722 Show fit	11.91	ENSRNOT00000048550	Camkmt Links NCBI RGD Ensembl Show fit	calmodulin-lysine N-methyltransferase
chr8_+_128133431 Show fit	11.72	ENSRNOT00000020174	Exog Links NCBI RGD Ensembl Show fit	exo/endonuclease G
chr3_-_163814799 Show fit	11.72	ENSRNOT00000055127	Znfx1 Links NCBI RGD Ensembl Show fit	zinc finger, NFX1-type containing 1
chr1_+_247519939 Show fit	10.92	ENSRNOT00000034421	Cd274 Links NCBI RGD Ensembl Show fit	CD274 molecule
chr11_-_29638922 Show fit	10.77	ENSRNOT00000048888	LOC100359671 Links NCBI RGD Ensembl Show fit	ribosomal protein L29-like
chr2_+_196120580 Show fit	10.36	ENSRNOT00000068528	Rfx5 Links NCBI RGD Ensembl Show fit	regulatory factor X5
chr10_-_87136026 Show fit	10.21	ENSRNOT00000014230 ENSRNOT00000083233	Smarce1 Links NCBI RGD Ensembl Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr10_-_16045835 Show fit	10.21	ENSRNOT00000064832	Cpeb4 Links NCBI RGD Ensembl Show fit	cytoplasmic polyadenylation element binding protein 4
chr4_-_88649216 Show fit	9.82	ENSRNOT00000058626	Herc6 Links NCBI RGD Ensembl Show fit	HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr12_-_41266430 Show fit	9.70	ENSRNOT00000001853 ENSRNOT00000081108	Oas1b Links NCBI RGD Ensembl Show fit	2-5 oligoadenylate synthetase 1B
chr16_-_71203609 Show fit	9.58	ENSRNOT00000088458	Nsd3 Links NCBI RGD Ensembl Show fit	nuclear receptor binding SET domain protein 3
chr9_+_119517101 Show fit	9.17	ENSRNOT00000020476	Lpin2 Links NCBI RGD Ensembl Show fit	lipin 2
chr14_+_19319299 Show fit	9.16	ENSRNOT00000086542	Ankrd17 Links NCBI RGD Ensembl Show fit	ankyrin repeat domain 17
chr15_-_93748742 Show fit	8.87	ENSRNOT00000093370	Mycbp2 Links NCBI RGD Ensembl Show fit	MYC binding protein 2, E3 ubiquitin protein ligase
chr13_-_102643223 Show fit	8.75	ENSRNOT00000003155	Hlx Links NCBI RGD Ensembl Show fit	H2.0-like homeobox
chr3_-_2770620 Show fit	8.57	ENSRNOT00000008253	Traf2 Links NCBI RGD Ensembl Show fit	Tnf receptor-associated factor 2
chr5_+_159735008 Show fit	8.48	ENSRNOT00000064310	Rsg1 Links NCBI RGD Ensembl Show fit	REM2 and RAB-like small GTPase 1
chr6_-_21135880 Show fit	8.46	ENSRNOT00000051239	Rasgrp3 Links NCBI RGD Ensembl Show fit	RAS guanyl releasing protein 3
chr4_-_120041238 Show fit	8.46	ENSRNOT00000073799	LOC100911337 Links NCBI RGD Ensembl Show fit	40S ribosomal protein S25-like
chr1_+_84009268 Show fit	8.26	ENSRNOT00000057230 ENSRNOT00000081121	RGD1560854 Links NCBI RGD Ensembl Show fit	similar to FLJ41131 protein
chr7_+_2635743 Show fit	8.13	ENSRNOT00000004223	Mip Links NCBI RGD Ensembl Show fit	major intrinsic protein of lens fiber
chr4_-_120414118 Show fit	8.05	ENSRNOT00000072795	LOC100911337 Links NCBI RGD Ensembl Show fit	40S ribosomal protein S25-like
chr5_+_159734838 Show fit	7.99	ENSRNOT00000079905	Rsg1 Links NCBI RGD Ensembl Show fit	REM2 and RAB-like small GTPase 1
chr3_+_72460889 Show fit	7.84	ENSRNOT00000012209	Tnks1bp1 Links NCBI RGD Ensembl Show fit	tankyrase 1 binding protein 1
chr16_+_18690649 Show fit	7.76	ENSRNOT00000015190	Mat1a Links NCBI RGD Ensembl Show fit	methionine adenosyltransferase 1A
chr14_-_81679082 Show fit	7.36	ENSRNOT00000077799	Rnf4 Links NCBI RGD Ensembl Show fit	ring finger protein 4
chr2_+_1410934 Show fit	6.98	ENSRNOT00000013625 ENSRNOT00000080222	Erap1 Links NCBI RGD Ensembl Show fit	endoplasmic reticulum aminopeptidase 1
chr5_-_24489468 Show fit	6.91	ENSRNOT00000081395	Ints8 Links NCBI RGD Ensembl Show fit	integrator complex subunit 8
chr6_-_102196138 Show fit	6.84	ENSRNOT00000014132	Tmem229b Links NCBI RGD Ensembl Show fit	transmembrane protein 229B
chr8_-_108261021 Show fit	6.80	ENSRNOT00000040710	LOC100912210 Links NCBI RGD Ensembl Show fit	40S ribosomal protein S25-like
chr1_+_53220397 Show fit	5.80	ENSRNOT00000089989	AABR07001573.1 Links NCBI RGD Ensembl Show fit
chr1_+_64046377 Show fit	5.49	ENSRNOT00000085010	Tmc4 Links NCBI RGD Ensembl Show fit	transmembrane channel-like 4
chr19_-_19377492 Show fit	5.35	ENSRNOT00000080964	Nod2 Links NCBI RGD Ensembl Show fit	nucleotide-binding oligomerization domain containing 2
chr2_+_189062443 Show fit	5.34	ENSRNOT00000028181	Adar Links NCBI RGD Ensembl Show fit	adenosine deaminase, RNA-specific
chr1_+_221043119 Show fit	4.85	ENSRNOT00000028185	Map3k11 Links NCBI RGD Ensembl Show fit	mitogen-activated protein kinase kinase kinase 11
chr1_+_72756809 Show fit	4.78	ENSRNOT00000082423	Ppp6r1 Links NCBI RGD Ensembl Show fit	protein phosphatase 6, regulatory subunit 1
chr6_-_1466201 Show fit	4.75	ENSRNOT00000089185	Eif2ak2 Links NCBI RGD Ensembl Show fit	eukaryotic translation initiation factor 2-alpha kinase 2
chr2_-_148722263 Show fit	4.61	ENSRNOT00000017868	Serp1 Links NCBI RGD Ensembl Show fit	stress-associated endoplasmic reticulum protein 1
chr13_-_52514875 Show fit	4.56	ENSRNOT00000064758	Nav1 Links NCBI RGD Ensembl Show fit	neuron navigator 1
chr1_+_64114721 Show fit	4.48	ENSRNOT00000080466	Tmc4 Links NCBI RGD Ensembl Show fit	transmembrane channel-like 4
chr1_+_255564409 Show fit	4.38	ENSRNOT00000081786	Btaf1 Links NCBI RGD Ensembl Show fit	B-TFIID TATA-box binding protein associated factor 1
chr17_-_84247038 Show fit	4.18	ENSRNOT00000068553	Nebl Links NCBI RGD Ensembl Show fit	nebulette
chr5_-_78183122 Show fit	4.07	ENSRNOT00000002083 ENSRNOT00000067076	Fkbp15 Links NCBI RGD Ensembl Show fit	FK506 binding protein 15
chr18_+_56364620 Show fit	3.63	ENSRNOT00000068535 ENSRNOT00000086033	Pdgfrb Links NCBI RGD Ensembl Show fit	platelet derived growth factor receptor beta
chr1_+_219439953 Show fit	3.46	ENSRNOT00000025282	Ppp1ca Links NCBI RGD Ensembl Show fit	protein phosphatase 1 catalytic subunit alpha
chrX_+_128409472 Show fit	3.31	ENSRNOT00000078482	Xiap Links NCBI RGD Ensembl Show fit	X-linked inhibitor of apoptosis
chr7_-_101140308 Show fit	3.25	ENSRNOT00000006279	Fam84b Links NCBI RGD Ensembl Show fit	family with sequence similarity 84, member B
chr5_+_141572536 Show fit	3.17	ENSRNOT00000023514	Rragc Links NCBI RGD Ensembl Show fit	Ras-related GTP binding C
chr12_-_9501213 Show fit	3.14	ENSRNOT00000071942	Pdx1 Links NCBI RGD Ensembl Show fit	pancreatic and duodenal homeobox 1
chr1_-_102849430 Show fit	3.13	ENSRNOT00000086856	Saa4 Links NCBI RGD Ensembl Show fit	serum amyloid A4
chr5_+_156603725 Show fit	2.65	ENSRNOT00000075852	Hp1bp3 Links NCBI RGD Ensembl Show fit	heterochromatin protein 1, binding protein 3
chr9_-_93125014 Show fit	2.56	ENSRNOT00000023829	Htr2b Links NCBI RGD Ensembl Show fit	5-hydroxytryptamine receptor 2B
chr5_-_131860637 Show fit	2.47	ENSRNOT00000064569 ENSRNOT00000080242	Slc5a9 Links NCBI RGD Ensembl Show fit	solute carrier family 5 member 9
chr1_+_41323194 Show fit	1.65	ENSRNOT00000026350	Esr1 Links NCBI RGD Ensembl Show fit	estrogen receptor 1
chr8_-_62948720 Show fit	1.54	ENSRNOT00000075476	Islr Links NCBI RGD Ensembl Show fit	immunoglobulin superfamily containing leucine-rich repeat
chr20_+_8325041 Show fit	1.50	ENSRNOT00000000640	Cmtr1 Links NCBI RGD Ensembl Show fit	cap methyltransferase 1
chr1_-_198008893 Show fit	1.34	ENSRNOT00000025950	Il27 Links NCBI RGD Ensembl Show fit	interleukin 27
chr4_-_13565838 Show fit	0.92	ENSRNOT00000048882	Olr987 Links NCBI RGD Ensembl Show fit	olfactory receptor 987
chr20_+_55253686 Show fit	0.62	ENSRNOT00000057016	Ascc3 Links NCBI RGD Ensembl Show fit	activating signal cointegrator 1 complex subunit 3
chr7_+_132857628 Show fit	0.49	ENSRNOT00000005438	Lrrk2 Links NCBI RGD Ensembl Show fit	leucine-rich repeat kinase 2
chr1_-_47213749 Show fit	0.18	ENSRNOT00000024656	Dynlt1 Links NCBI RGD Ensembl Show fit	dynein light chain Tctex-type 1

View svg image
View png image

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
44.7	178.7	GO:0097026	dendritic cell dendrite assembly(GO:0097026)
21.6	64.7	GO:0002223	stimulatory C-type lectin receptor signaling pathway(GO:0002223) negative regulation of natural killer cell chemotaxis(GO:2000502)
19.5	58.5	GO:0046967	cytosol to ER transport(GO:0046967) peptide antigen transport(GO:0046968)
18.9	75.7	GO:0050904	CD8-positive, alpha-beta T cell extravasation(GO:0035697) diapedesis(GO:0050904) cellular response to vitamin K(GO:0071307)
16.1	64.4	GO:0002343	peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344) cellular response to molecule of fungal origin(GO:0071226)
16.1	48.3	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
15.3	45.8	GO:0002731	negative regulation of dendritic cell cytokine production(GO:0002731)
14.6	73.0	GO:0002636	positive regulation of germinal center formation(GO:0002636)
14.5	72.4	GO:0032020	ISG15-protein conjugation(GO:0032020)
13.1	39.4	GO:0070212	regulation of chromatin assembly(GO:0010847) protein poly-ADP-ribosylation(GO:0070212)
13.0	117.1	GO:0003374	dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
13.0	39.0	GO:0007356	thorax and anterior abdomen determination(GO:0007356)
12.2	133.7	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
11.9	35.6	GO:0002644	negative regulation of tolerance induction(GO:0002644)
11.2	44.8	GO:0019805	quinolinate biosynthetic process(GO:0019805)
11.0	132.2	GO:0038095	Fc-epsilon receptor signaling pathway(GO:0038095)
10.8	43.1	GO:1901423	response to benzene(GO:1901423)
10.7	64.1	GO:0045345	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
8.5	34.1	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
8.5	25.4	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
7.9	15.9	GO:0002481	antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
7.9	23.7	GO:0002397	MHC class I protein complex assembly(GO:0002397)
7.7	46.3	GO:0001835	blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
7.7	23.0	GO:0048014	Tie signaling pathway(GO:0048014)
7.3	36.6	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
7.0	55.8	GO:0032621	interleukin-18 production(GO:0032621)
7.0	27.8	GO:0016332	establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
6.9	13.8	GO:0002589	regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
6.9	27.4	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
6.5	45.6	GO:0097527	necroptotic signaling pathway(GO:0097527)
6.4	19.2	GO:0033385	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
6.4	32.0	GO:0052041	negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
6.3	101.5	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
6.3	25.3	GO:0034240	negative regulation of macrophage fusion(GO:0034240)
6.3	176.2	GO:0035458	cellular response to interferon-beta(GO:0035458)
6.2	49.9	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
5.7	45.5	GO:0018377	protein myristoylation(GO:0018377)
5.5	38.8	GO:0045351	type I interferon biosynthetic process(GO:0045351)
5.3	16.0	GO:1902226	regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
5.3	21.1	GO:0039530	MDA-5 signaling pathway(GO:0039530)
3.9	31.2	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
3.7	36.9	GO:0051798	positive regulation of hair follicle development(GO:0051798)
3.6	14.4	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
3.6	14.2	GO:0009597	detection of virus(GO:0009597)
3.5	28.3	GO:0036018	response to cobalamin(GO:0033590) cellular response to erythropoietin(GO:0036018) positive regulation of protein kinase C signaling(GO:0090037)
3.3	65.7	GO:0035634	response to stilbenoid(GO:0035634)
3.2	16.1	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
3.2	19.3	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
3.0	107.4	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
3.0	26.6	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
2.9	14.6	GO:0072734	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
2.9	40.9	GO:0033004	negative regulation of mast cell activation(GO:0033004)
2.9	8.6	GO:1903719	regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
2.8	14.1	GO:2000327	positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
2.8	22.3	GO:0016584	nucleosome positioning(GO:0016584)
2.8	30.5	GO:0006957	complement activation, alternative pathway(GO:0006957)
2.7	30.1	GO:2000258	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
2.7	35.4	GO:0042832	defense response to protozoan(GO:0042832)
2.7	5.3	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
2.2	8.7	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
2.2	34.5	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
2.1	12.4	GO:0071357	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
1.9	19.3	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
1.9	25.0	GO:0010818	T cell chemotaxis(GO:0010818)
1.8	7.4	GO:0090234	regulation of kinetochore assembly(GO:0090234)
1.7	40.4	GO:0010390	histone monoubiquitination(GO:0010390)
1.6	116.6	GO:0019882	antigen processing and presentation(GO:0019882)
1.6	34.4	GO:0071474	cellular hyperosmotic response(GO:0071474)
1.6	14.6	GO:1900115	extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
1.4	195.5	GO:0051607	defense response to virus(GO:0051607)
1.4	16.9	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
1.4	4.2	GO:0071691	cardiac muscle thin filament assembly(GO:0071691)
1.4	17.9	GO:0016446	somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
1.2	42.0	GO:0046825	regulation of protein export from nucleus(GO:0046825)
1.2	15.9	GO:0051601	exocyst localization(GO:0051601)
1.2	19.4	GO:0032897	negative regulation of viral transcription(GO:0032897)
1.2	3.6	GO:0038086	VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
1.2	8.1	GO:0015722	canalicular bile acid transport(GO:0015722)
1.0	25.7	GO:0002820	negative regulation of adaptive immune response(GO:0002820)
1.0	4.8	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.9	2.7	GO:0097298	regulation of nucleus size(GO:0097298)
0.9	27.9	GO:0006270	DNA replication initiation(GO:0006270)
0.9	10.2	GO:0006337	nucleosome disassembly(GO:0006337)
0.8	17.5	GO:0032689	negative regulation of interferon-gamma production(GO:0032689)
0.8	3.1	GO:0010157	response to chlorate(GO:0010157)
0.7	8.9	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
0.7	42.7	GO:0070206	protein trimerization(GO:0070206)
0.5	31.6	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.5	15.0	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.5	2.6	GO:0071502	positive regulation of phosphatidylinositol biosynthetic process(GO:0010513) cellular response to temperature stimulus(GO:0071502)
0.5	50.9	GO:0031016	pancreas development(GO:0031016)
0.5	1.5	GO:0036451	cap mRNA methylation(GO:0036451)
0.4	3.3	GO:1902916	positive regulation of protein polyubiquitination(GO:1902916)
0.4	1.7	GO:1990375	baculum development(GO:1990375)
0.4	26.4	GO:0007004	RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.4	16.2	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.4	4.4	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.3	4.8	GO:0007256	activation of JNKK activity(GO:0007256)
0.3	7.8	GO:0031954	positive regulation of peptidyl-threonine phosphorylation(GO:0010800) positive regulation of protein autophosphorylation(GO:0031954)
0.3	3.5	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.3	6.9	GO:0016180	snRNA processing(GO:0016180)
0.3	4.6	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.3	9.2	GO:0019432	triglyceride biosynthetic process(GO:0019432)
0.2	0.5	GO:0035564	regulation of kidney size(GO:0035564)
0.2	0.2	GO:0019060	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.2	21.5	GO:0018022	peptidyl-lysine methylation(GO:0018022)
0.2	52.4	GO:0045087	innate immune response(GO:0045087)
0.1	12.8	GO:0019395	fatty acid oxidation(GO:0019395)
0.1	53.4	GO:0006935	chemotaxis(GO:0006935)
0.1	32.2	GO:0006898	receptor-mediated endocytosis(GO:0006898)
0.1	4.8	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1	3.1	GO:0006953	acute-phase response(GO:0006953)
0.1	0.6	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.1	4.1	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.1	66.5	GO:0098655	cation transmembrane transport(GO:0098655)
0.1	11.7	GO:0090305	nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.0	0.1	GO:0036337	Fas signaling pathway(GO:0036337)
0.0	0.1	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.0	4.6	GO:0001578	microtubule bundle formation(GO:0001578)
0.0	2.5	GO:0006814	sodium ion transport(GO:0006814)
0.0	8.5	GO:0007265	Ras protein signal transduction(GO:0007265)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
21.6	129.7	GO:1990111	spermatoproteasome complex(GO:1990111)
11.7	82.1	GO:0042825	TAP complex(GO:0042825)
10.0	30.0	GO:0008537	proteasome activator complex(GO:0008537)
5.8	23.2	GO:0020005	symbiont-containing vacuole membrane(GO:0020005)
5.3	16.0	GO:1990682	CSF1-CSF1R complex(GO:1990682)
5.0	35.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
3.8	105.4	GO:0042629	mast cell granule(GO:0042629)
3.1	36.9	GO:0035631	CD40 receptor complex(GO:0035631)
2.7	8.1	GO:0046691	intracellular canaliculus(GO:0046691)
2.5	27.9	GO:0042555	MCM complex(GO:0042555)
2.2	13.1	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
1.4	70.9	GO:0016235	aggresome(GO:0016235)
1.4	27.4	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
1.2	21.9	GO:0030014	CCR4-NOT complex(GO:0030014)
1.1	46.3	GO:0005771	multivesicular body(GO:0005771)
1.1	19.3	GO:0031258	lamellipodium membrane(GO:0031258)
1.1	5.3	GO:0044530	supraspliceosomal complex(GO:0044530)
1.0	8.1	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
1.0	323.7	GO:0009897	external side of plasma membrane(GO:0009897)
1.0	24.0	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.9	22.2	GO:0001891	phagocytic cup(GO:0001891)
0.9	10.2	GO:0071564	npBAF complex(GO:0071564)
0.6	15.9	GO:0000145	exocyst(GO:0000145)
0.5	8.5	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.5	23.0	GO:0009925	basal plasma membrane(GO:0009925)
0.5	36.9	GO:0045095	keratin filament(GO:0045095)
0.5	46.9	GO:0072562	blood microparticle(GO:0072562)
0.4	6.9	GO:0032039	integrator complex(GO:0032039)
0.4	26.4	GO:0005876	spindle microtubule(GO:0005876)
0.3	3.5	GO:0042587	glycogen granule(GO:0042587)
0.3	3.6	GO:0043202	lysosomal lumen(GO:0043202)
0.3	18.4	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.3	16.2	GO:0031594	neuromuscular junction(GO:0031594)
0.3	206.0	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.3	26.8	GO:0016605	PML body(GO:0016605)
0.3	337.1	GO:0005615	extracellular space(GO:0005615)
0.3	22.7	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.2	26.7	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.2	14.2	GO:0032587	ruffle membrane(GO:0032587)
0.2	4.6	GO:0043194	axon initial segment(GO:0043194)
0.2	107.7	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.2	90.9	GO:0005783	endoplasmic reticulum(GO:0005783)
0.2	521.7	GO:0005829	cytosol(GO:0005829)
0.1	24.3	GO:0016607	nuclear speck(GO:0016607)
0.1	4.2	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	4.1	GO:0005884	actin filament(GO:0005884)
0.1	9.2	GO:0031965	nuclear membrane(GO:0031965)
0.1	0.2	GO:0018995	host(GO:0018995) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	3.2	GO:0005764	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0	107.3	GO:0016021	integral component of membrane(GO:0016021)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
26.4	132.2	GO:0019770	IgG receptor activity(GO:0019770)
22.8	68.4	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
19.5	58.5	GO:0046980	peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
19.2	76.8	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
12.9	90.3	GO:0048019	receptor antagonist activity(GO:0048019)
11.3	102.1	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
8.1	48.3	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
7.9	23.7	GO:0046977	TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
6.5	148.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
6.3	25.4	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
6.2	36.9	GO:0042289	MHC class II protein binding(GO:0042289)
6.0	18.1	GO:0001716	L-amino-acid oxidase activity(GO:0001716)
5.4	16.1	GO:0001069	regulatory region RNA binding(GO:0001069)
5.3	16.0	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
5.0	44.8	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
4.5	135.3	GO:0008009	chemokine activity(GO:0008009)
4.5	120.6	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
4.3	30.0	GO:0061133	endopeptidase activator activity(GO:0061133)
4.3	25.7	GO:0048030	disaccharide binding(GO:0048030)
4.2	42.5	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
3.8	19.2	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
3.8	45.8	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
3.4	37.6	GO:0008641	small protein activating enzyme activity(GO:0008641)
2.9	64.7	GO:0042288	MHC class I protein binding(GO:0042288)
2.9	35.1	GO:0050897	cobalt ion binding(GO:0050897)
2.8	25.3	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
2.8	97.7	GO:0042605	peptide antigen binding(GO:0042605)
2.6	23.0	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
2.5	50.9	GO:0004806	triglyceride lipase activity(GO:0004806)
2.3	88.6	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
2.1	19.3	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
1.9	94.9	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
1.7	27.4	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
1.7	96.3	GO:0004520	endodeoxyribonuclease activity(GO:0004520)
1.6	4.8	GO:0004478	methionine adenosyltransferase activity(GO:0004478)
1.6	30.1	GO:0001848	complement binding(GO:0001848)
1.4	9.6	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
1.3	28.3	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
1.3	99.0	GO:0003725	double-stranded RNA binding(GO:0003725)
1.3	14.6	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
1.3	384.8	GO:0003924	GTPase activity(GO:0003924)
1.2	65.6	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
1.2	7.4	GO:0033142	progesterone receptor binding(GO:0033142)
1.2	35.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
1.2	4.8	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
1.2	3.6	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
1.1	7.8	GO:0071532	ankyrin repeat binding(GO:0071532)
1.1	15.0	GO:0017154	semaphorin receptor activity(GO:0017154)
1.1	11.7	GO:0008409	5'-3' exonuclease activity(GO:0008409)
1.0	45.3	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
1.0	53.7	GO:0000049	tRNA binding(GO:0000049)
0.9	10.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.9	86.3	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.8	14.1	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.8	39.7	GO:0001786	phosphatidylserine binding(GO:0001786)
0.8	5.3	GO:0050700	CARD domain binding(GO:0050700)
0.8	62.3	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.7	37.9	GO:0005044	scavenger receptor activity(GO:0005044)
0.7	28.6	GO:0003678	DNA helicase activity(GO:0003678)
0.6	8.1	GO:0015250	water channel activity(GO:0015250)
0.6	41.3	GO:0033613	activating transcription factor binding(GO:0033613)
0.6	25.7	GO:0001784	phosphotyrosine binding(GO:0001784)
0.5	9.2	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.5	1.5	GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.4	1.7	GO:0031798	type 1 metabotropic glutamate receptor binding(GO:0031798)
0.3	97.0	GO:0030246	carbohydrate binding(GO:0030246)
0.2	2.5	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.2	4.2	GO:0005523	tropomyosin binding(GO:0005523)
0.2	11.9	GO:0016279	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.2	34.5	GO:0051015	actin filament binding(GO:0051015)
0.2	3.5	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2	27.8	GO:0030165	PDZ domain binding(GO:0030165)
0.2	66.5	GO:0005261	cation channel activity(GO:0005261)
0.2	2.6	GO:0051378	serotonin binding(GO:0051378)
0.2	12.7	GO:0001047	core promoter binding(GO:0001047)
0.1	30.5	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	15.9	GO:0001948	glycoprotein binding(GO:0001948)
0.1	46.8	GO:0003712	transcription cofactor activity(GO:0003712)
0.1	2.7	GO:0031491	nucleosome binding(GO:0031491)
0.1	9.4	GO:0031490	chromatin DNA binding(GO:0031490)
0.1	4.1	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1	8.5	GO:0005088	Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.1	0.6	GO:0031386	protein tag(GO:0031386)
0.1	4.8	GO:0019903	protein phosphatase binding(GO:0019903)
0.0	68.3	GO:0003677	DNA binding(GO:0003677)
0.0	18.7	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.0	2.1	GO:0005125	cytokine activity(GO:0005125)
0.0	1.3	GO:0005126	cytokine receptor binding(GO:0005126)
0.0	9.9	GO:0008270	zinc ion binding(GO:0008270)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.2	148.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
5.5	76.5	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
2.9	91.6	ST GA12 PATHWAY	G alpha 12 Pathway
2.2	55.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
2.0	48.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
2.0	75.7	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
1.1	36.2	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
1.1	35.6	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
1.1	24.6	PID IL12 2PATHWAY	IL12-mediated signaling events
1.1	35.1	PID MYC PATHWAY	C-MYC pathway
1.1	36.9	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.9	40.1	PID IL4 2PATHWAY	IL4-mediated signaling events
0.8	18.0	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.8	25.4	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.8	36.3	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.8	63.9	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.7	36.9	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.7	10.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.7	23.0	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.6	190.7	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.6	95.8	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.5	14.4	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.4	1.3	PID IL27 PATHWAY	IL27-mediated signaling events
0.4	8.5	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.4	5.3	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.3	16.9	PID FANCONI PATHWAY	Fanconi anemia pathway
0.3	4.8	PID IFNG PATHWAY	IFN-gamma pathway
0.3	3.6	PID S1P S1P1 PATHWAY	S1P1 pathway
0.3	11.7	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.3	62.0	NABA MATRISOME ASSOCIATED	Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.3	27.5	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.1	3.5	PID ALK1 PATHWAY	ALK1 signaling events
0.1	5.9	PID E2F PATHWAY	E2F transcription factor network
0.1	3.2	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	3.1	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	4.8	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
11.1	665.9	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
7.1	77.8	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
6.1	304.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
5.5	71.4	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
5.3	15.9	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
4.7	225.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
4.5	126.8	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
4.3	8.6	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
4.1	28.5	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
3.9	65.5	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
2.5	27.9	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
2.4	16.9	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
2.4	35.6	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
2.3	30.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
2.2	22.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
1.9	55.9	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
1.7	64.4	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
1.6	23.0	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
1.4	30.1	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
1.4	64.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
1.3	12.0	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.9	15.0	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.9	21.9	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.8	19.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.7	8.1	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.7	9.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.6	14.6	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4	5.3	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.3	56.5	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.2	3.5	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2	8.5	REACTOME SIGNALING BY THE B CELL RECEPTOR BCR	Genes involved in Signaling by the B Cell Receptor (BCR)
0.2	2.6	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.2	4.8	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	3.1	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	4.6	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1	13.2	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.1	3.3	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.1	4.8	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	3.6	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	1.7	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway