ISMARA results: Sp1

Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Sp1

Z-value: 2.01

Motif logo

Transcription factors associated with Sp1

Gene Symbol	Gene ID	Gene Info
Sp1 NCBI RGD Ensembl	ENSRNOG00000014084	Sp1 transcription factor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Sp1	rn6_v1_chr7_+_144014173_144014173	-0.02	7.9e-01	Click!

Activity profile of Sp1 motif

Sorted Z-values of Sp1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr2_+_34186091 Show fit	72.12	ENSRNOT00000016129	Sgtb NCBI RGD Ensembl Show fit	small glutamine rich tetratricopeptide repeat containing beta
chr1_-_216663720 Show fit	71.89	ENSRNOT00000078944 ENSRNOT00000077409	Cdkn1c NCBI RGD Ensembl Show fit	cyclin-dependent kinase inhibitor 1C
chr6_+_132246602 Show fit	66.42	ENSRNOT00000009896	Cyp46a1 NCBI RGD Ensembl Show fit	cytochrome P450, family 46, subfamily a, polypeptide 1
chr1_+_166564664 Show fit	63.48	ENSRNOT00000090959	Pde2a NCBI RGD Ensembl Show fit	phosphodiesterase 2A
chr5_+_156876706 Show fit	59.36	ENSRNOT00000021864	Camk2n1 NCBI RGD Ensembl Show fit	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr7_+_123043503 Show fit	59.34	ENSRNOT00000026258 ENSRNOT00000086355	Tef NCBI RGD Ensembl Show fit	TEF, PAR bZIP transcription factor
chr3_+_152552822 Show fit	57.35	ENSRNOT00000089719	Epb41l1 NCBI RGD Ensembl Show fit	erythrocyte membrane protein band 4.1-like 1
chr1_+_80195532 Show fit	57.31	ENSRNOT00000022528	Rtn2 NCBI RGD Ensembl Show fit	reticulon 2
chr5_-_164971903 Show fit	57.13	ENSRNOT00000067059	Fbxo44 NCBI RGD Ensembl Show fit	F-box protein 44
chr16_-_20439206 Show fit	56.45	ENSRNOT00000026391	Rab3a NCBI RGD Ensembl Show fit	RAB3A, member RAS oncogene family
chr7_-_11353713 Show fit	56.29	ENSRNOT00000061132	Zfr2 NCBI RGD Ensembl Show fit	zinc finger RNA binding protein 2
chr3_+_80072489 Show fit	55.37	ENSRNOT00000057176	Pacsin3 NCBI RGD Ensembl Show fit	protein kinase C and casein kinase substrate in neurons 3
chr13_-_91872954 Show fit	55.22	ENSRNOT00000004613 ENSRNOT00000079263	Cadm3 NCBI RGD Ensembl Show fit	cell adhesion molecule 3
chr5_-_33182147 Show fit	54.61	ENSRNOT00000080358	Maged2 NCBI RGD Ensembl Show fit	MAGE family member D2
chr1_-_89483988 Show fit	54.53	ENSRNOT00000028603	Fxyd7 NCBI RGD Ensembl Show fit	FXYD domain-containing ion transport regulator 7
chr5_+_139783951 Show fit	54.35	ENSRNOT00000081333	Rims3 NCBI RGD Ensembl Show fit	regulating synaptic membrane exocytosis 3
chr9_+_9961021 Show fit	54.11	ENSRNOT00000075767	Tubb4a NCBI RGD Ensembl Show fit	tubulin, beta 4A class IVa
chr3_+_58632476 Show fit	53.47	ENSRNOT00000010630	Rapgef4 NCBI RGD Ensembl Show fit	Rap guanine nucleotide exchange factor 4
chr7_-_70552897 Show fit	51.41	ENSRNOT00000080594	Kif5a NCBI RGD Ensembl Show fit	kinesin family member 5A
chr10_+_65586504 Show fit	50.20	ENSRNOT00000015535 ENSRNOT00000046388	Aldoc NCBI RGD Ensembl Show fit	aldolase, fructose-bisphosphate C
chr6_+_144384773 Show fit	49.62	ENSRNOT00000006942	Ptprn2 NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, receptor type N2
chr7_-_132757558 Show fit	49.03	ENSRNOT00000021153	Slc2a13 NCBI RGD Ensembl Show fit	solute carrier family 2 member 13
chr13_-_86671515 Show fit	48.72	ENSRNOT00000082869	AABR07021704.1 NCBI RGD Ensembl Show fit
chr4_+_147037179 Show fit	48.69	ENSRNOT00000011292	Syn2 NCBI RGD Ensembl Show fit	synapsin II
chr20_+_5050327 Show fit	48.09	ENSRNOT00000083353	Ddah2 NCBI RGD Ensembl Show fit	dimethylarginine dimethylaminohydrolase 2
chr10_-_82197848 Show fit	47.13	ENSRNOT00000081307	Cacna1g NCBI RGD Ensembl Show fit	calcium voltage-gated channel subunit alpha1 G
chr1_+_198383201 Show fit	46.62	ENSRNOT00000037405	Sez6l2 NCBI RGD Ensembl Show fit	seizure related 6 homolog like 2
chr1_-_101351879 Show fit	46.54	ENSRNOT00000028142	Ppfia3 NCBI RGD Ensembl Show fit	PTPRF interacting protein alpha 3
chr9_-_82461903 Show fit	46.28	ENSRNOT00000026654	Ptprn NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, receptor type, N
chr10_+_77755216 Show fit	46.04	ENSRNOT00000087765	Mmd NCBI RGD Ensembl Show fit	monocyte to macrophage differentiation-associated
chr8_-_109621408 Show fit	45.90	ENSRNOT00000087398	Ppp2r3a NCBI RGD Ensembl Show fit	protein phosphatase 2, regulatory subunit B'', alpha
chr4_-_157679962 Show fit	45.82	ENSRNOT00000050443	Gapdh NCBI RGD Ensembl Show fit	glyceraldehyde-3-phosphate dehydrogenase
chrX_+_123205869 Show fit	45.79	ENSRNOT00000017101 ENSRNOT00000079231	Pgrmc1 NCBI RGD Ensembl Show fit	progesterone receptor membrane component 1
chr10_-_97896525 Show fit	45.31	ENSRNOT00000005172	Wipi1 NCBI RGD Ensembl Show fit	WD repeat domain, phosphoinositide interacting 1
chr14_+_83752393 Show fit	45.18	ENSRNOT00000081123	Selenom NCBI RGD Ensembl Show fit	selenoprotein M
chr3_-_163935617 Show fit	44.77	ENSRNOT00000074023	Kcnb1 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily B member 1
chr1_-_88908750 Show fit	44.68	ENSRNOT00000028297	Aplp1 NCBI RGD Ensembl Show fit	amyloid beta precursor like protein 1
chr10_+_86657285 Show fit	44.66	ENSRNOT00000087346	Thra NCBI RGD Ensembl Show fit	thyroid hormone receptor alpha
chr12_+_25173005 Show fit	44.13	ENSRNOT00000033200 ENSRNOT00000091328	Clip2 NCBI RGD Ensembl Show fit	CAP-GLY domain containing linker protein 2
chr10_-_91047177 Show fit	43.85	ENSRNOT00000003986	C1ql1 NCBI RGD Ensembl Show fit	complement C1q like 1
chr15_-_28314459 Show fit	43.76	ENSRNOT00000042055 ENSRNOT00000040540	Ndrg2 NCBI RGD Ensembl Show fit	NDRG family member 2
chr3_-_105279462 Show fit	43.55	ENSRNOT00000010679	Scg5 NCBI RGD Ensembl Show fit	secretogranin V
chr10_-_56444847 Show fit	42.81	ENSRNOT00000056872 ENSRNOT00000092662	Nlgn2 NCBI RGD Ensembl Show fit	neuroligin 2
chr7_-_115988036 Show fit	42.68	ENSRNOT00000076822	Lynx1 NCBI RGD Ensembl Show fit	Ly6/neurotoxin 1
chr3_+_41019898 Show fit	42.62	ENSRNOT00000007335	Kcnj3 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily J member 3
chr7_-_145154131 Show fit	42.37	ENSRNOT00000055271	Ppp1r1a NCBI RGD Ensembl Show fit	protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr7_-_130128589 Show fit	42.35	ENSRNOT00000079777 ENSRNOT00000009325	Mapk11 NCBI RGD Ensembl Show fit	mitogen-activated protein kinase 11
chr10_-_103919605 Show fit	42.06	ENSRNOT00000004718	Hid1 NCBI RGD Ensembl Show fit	HID1 domain containing
chr13_+_70379346 Show fit	41.92	ENSRNOT00000038183	Nmnat2 NCBI RGD Ensembl Show fit	nicotinamide nucleotide adenylyltransferase 2
chrX_+_157095937 Show fit	41.74	ENSRNOT00000091792	Bcap31 NCBI RGD Ensembl Show fit	B-cell receptor-associated protein 31
chr13_-_52197205 Show fit	41.50	ENSRNOT00000009712	Shisa4 NCBI RGD Ensembl Show fit	shisa family member 4
chr3_+_113251778 Show fit	41.49	ENSRNOT00000083005	Map1a NCBI RGD Ensembl Show fit	microtubule-associated protein 1A
chr8_-_132345708 Show fit	41.08	ENSRNOT00000006300	Tmem158 NCBI RGD Ensembl Show fit	transmembrane protein 158
chr14_-_36554580 Show fit	41.01	ENSRNOT00000002869	Rasl11b NCBI RGD Ensembl Show fit	RAS-like family 11 member B
chr5_+_28395296 Show fit	40.95	ENSRNOT00000009375	Tmem55a NCBI RGD Ensembl Show fit	transmembrane protein 55A
chr8_+_44136496 Show fit	40.93	ENSRNOT00000087022	Scn3b NCBI RGD Ensembl Show fit	sodium voltage-gated channel beta subunit 3
chr5_-_144779212 Show fit	40.91	ENSRNOT00000016230	Ncdn NCBI RGD Ensembl Show fit	neurochondrin
chr1_+_234252757 Show fit	40.75	ENSRNOT00000091814	Rorb NCBI RGD Ensembl Show fit	RAR-related orphan receptor B
chr8_+_55178289 Show fit	40.51	ENSRNOT00000059127	Cryab NCBI RGD Ensembl Show fit	crystallin, alpha B
chr4_-_169999873 Show fit	40.48	ENSRNOT00000011697	Grin2b NCBI RGD Ensembl Show fit	glutamate ionotropic receptor NMDA type subunit 2B
chr1_-_64099277 Show fit	40.41	ENSRNOT00000084846	Tsen34 NCBI RGD Ensembl Show fit	tRNA splicing endonuclease subunit 34
chr10_-_39405311 Show fit	40.41	ENSRNOT00000074616	Pdlim4 NCBI RGD Ensembl Show fit	PDZ and LIM domain 4
chr4_-_16130848 Show fit	40.14	ENSRNOT00000042914	Cacna2d1 NCBI RGD Ensembl Show fit	calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr19_+_37476095 Show fit	39.91	ENSRNOT00000092794 ENSRNOT00000023130	Hsd11b2 NCBI RGD Ensembl Show fit	hydroxysteroid 11-beta dehydrogenase 2
chr1_-_146556171 Show fit	39.91	ENSRNOT00000017636	Arnt2 NCBI RGD Ensembl Show fit	aryl hydrocarbon receptor nuclear translocator 2
chr2_+_27107318 Show fit	39.88	ENSRNOT00000019553	Arhgef26 NCBI RGD Ensembl Show fit	Rho guanine nucleotide exchange factor 26
chr2_-_188138177 Show fit	39.69	ENSRNOT00000027474	Syt11 NCBI RGD Ensembl Show fit	synaptotagmin 11
chr14_-_85191557 Show fit	39.68	ENSRNOT00000011604	Nefh NCBI RGD Ensembl Show fit	neurofilament heavy
chr11_-_31752243 Show fit	39.23	ENSRNOT00000002775	Tmem50b NCBI RGD Ensembl Show fit	transmembrane protein 50B
chr1_-_211265161 Show fit	38.95	ENSRNOT00000080041 ENSRNOT00000023477	Bnip3 NCBI RGD Ensembl Show fit	BCL2 interacting protein 3
chrX_+_107370431 Show fit	38.95	ENSRNOT00000044372	Tceal1 NCBI RGD Ensembl Show fit	transcription elongation factor A like 1
chrX_+_39711201 Show fit	38.93	ENSRNOT00000080512 ENSRNOT00000009802	Cnksr2 NCBI RGD Ensembl Show fit	connector enhancer of kinase suppressor of Ras 2
chr1_+_101161252 Show fit	38.88	ENSRNOT00000028064 ENSRNOT00000064184	Slc17a7 NCBI RGD Ensembl Show fit	solute carrier family 17 member 7
chr6_-_28464118 Show fit	38.55	ENSRNOT00000068214	Efr3b NCBI RGD Ensembl Show fit	EFR3 homolog B
chr4_+_89078711 Show fit	38.30	ENSRNOT00000010241	Herc3 NCBI RGD Ensembl Show fit	HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr14_+_78640620 Show fit	38.00	ENSRNOT00000034730	Wfs1 NCBI RGD Ensembl Show fit	wolframin ER transmembrane glycoprotein
chr1_+_162768156 Show fit	37.96	ENSRNOT00000049321	Pak1 NCBI RGD Ensembl Show fit	p21 (RAC1) activated kinase 1
chr5_+_155812105 Show fit	37.94	ENSRNOT00000039341	AABR07073181.1 NCBI RGD Ensembl Show fit
chr5_+_128501847 Show fit	37.83	ENSRNOT00000010645	Rab3b NCBI RGD Ensembl Show fit	RAB3B, member RAS oncogene family
chr4_-_16130563 Show fit	37.78	ENSRNOT00000090240 ENSRNOT00000034969	Cacna2d1 NCBI RGD Ensembl Show fit	calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr10_-_46720907 Show fit	37.52	ENSRNOT00000083093 ENSRNOT00000067866	Tom1l2 NCBI RGD Ensembl Show fit	target of myb1 like 2 membrane trafficking protein
chr2_+_121165137 Show fit	37.40	ENSRNOT00000016236	Sox2 NCBI RGD Ensembl Show fit	SRY box 2
chr2_+_174013288 Show fit	37.12	ENSRNOT00000013904	Serpini1 NCBI RGD Ensembl Show fit	serpin family I member 1
chr14_+_60123169 Show fit	36.87	ENSRNOT00000006610	Sel1l3 NCBI RGD Ensembl Show fit	SEL1L family member 3
chr2_+_207923775 Show fit	36.66	ENSRNOT00000019997 ENSRNOT00000051835	Kcnd3 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily D member 3
chr9_+_96210750 Show fit	36.64	ENSRNOT00000026312	Sh3bp4 NCBI RGD Ensembl Show fit	SH3-domain binding protein 4
chr9_+_82674202 Show fit	36.54	ENSRNOT00000027208	Tmem198 NCBI RGD Ensembl Show fit	transmembrane protein 198
chr7_+_12433933 Show fit	36.34	ENSRNOT00000060690	Cbarp NCBI RGD Ensembl Show fit	CACN beta subunit associated regulatory protein
chr20_+_5049496 Show fit	36.20	ENSRNOT00000088251 ENSRNOT00000001118	Ddah2 NCBI RGD Ensembl Show fit	dimethylarginine dimethylaminohydrolase 2
chrX_-_6620722 Show fit	36.19	ENSRNOT00000066674	Maoa NCBI RGD Ensembl Show fit	monoamine oxidase A
chr3_+_113319456 Show fit	36.05	ENSRNOT00000051354	Ckmt1 NCBI RGD Ensembl Show fit	creatine kinase, mitochondrial 1
chr6_+_10306405 Show fit	35.97	ENSRNOT00000090420 ENSRNOT00000080507	Epas1 NCBI RGD Ensembl Show fit	endothelial PAS domain protein 1
chr1_-_212548730 Show fit	35.78	ENSRNOT00000089729	Caly NCBI RGD Ensembl Show fit	calcyon neuron-specific vesicular protein
chrX_-_157139291 Show fit	35.69	ENSRNOT00000092123	Slc6a8 NCBI RGD Ensembl Show fit	solute carrier family 6 member 8
chrX_-_54303729 Show fit	35.54	ENSRNOT00000087919 ENSRNOT00000064340 ENSRNOT00000051249 ENSRNOT00000087547	Gk NCBI RGD Ensembl Show fit	glycerol kinase
chr5_-_58019836 Show fit	35.45	ENSRNOT00000066977	Enho NCBI RGD Ensembl Show fit	energy homeostasis associated
chr1_-_170464341 Show fit	35.36	ENSRNOT00000024850	Trim3 NCBI RGD Ensembl Show fit	tripartite motif-containing 3
chr8_-_49045154 Show fit	35.29	ENSRNOT00000088034	Phldb1 NCBI RGD Ensembl Show fit	pleckstrin homology-like domain, family B, member 1
chr10_-_65766050 Show fit	35.19	ENSRNOT00000013639	Sarm1 NCBI RGD Ensembl Show fit	sterile alpha and TIR motif containing 1
chr9_+_17340341 Show fit	35.06	ENSRNOT00000026637 ENSRNOT00000026559 ENSRNOT00000042790 ENSRNOT00000044163 ENSRNOT00000083811	Vegfa NCBI RGD Ensembl Show fit	vascular endothelial growth factor A
chr19_-_9777465 Show fit	34.97	ENSRNOT00000017413	Ndrg4 NCBI RGD Ensembl Show fit	NDRG family member 4
chr10_+_56445647 Show fit	34.69	ENSRNOT00000056870	Tmem256 NCBI RGD Ensembl Show fit	transmembrane protein 256
chr9_-_100253609 Show fit	34.66	ENSRNOT00000036061	Kif1a NCBI RGD Ensembl Show fit	kinesin family member 1A
chr17_-_10364503 Show fit	34.60	ENSRNOT00000086380 ENSRNOT00000041709	Tspan17 NCBI RGD Ensembl Show fit	tetraspanin 17
chr2_-_148050423 Show fit	34.44	ENSRNOT00000064506 ENSRNOT00000023469	LOC100909840 NCBI RGD Ensembl Show fit	profilin-2-like
chr13_-_70783515 Show fit	34.32	ENSRNOT00000003605	Lamc1 NCBI RGD Ensembl Show fit	laminin subunit gamma 1
chr8_+_118333706 Show fit	34.32	ENSRNOT00000028278	Cspg5 NCBI RGD Ensembl Show fit	chondroitin sulfate proteoglycan 5
chr4_-_52350624 Show fit	34.24	ENSRNOT00000060476	Tmem229a NCBI RGD Ensembl Show fit	transmembrane protein 229A
chr2_+_218951451 Show fit	34.22	ENSRNOT00000019190	Extl2 NCBI RGD Ensembl Show fit	exostosin-like glycosyltransferase 2
chrX_+_20484517 Show fit	33.96	ENSRNOT00000093701	FAM120C NCBI RGD Ensembl Show fit	family with sequence similarity 120C
chr3_+_161425988 Show fit	33.86	ENSRNOT00000065184	Slc12a5 NCBI RGD Ensembl Show fit	solute carrier family 12 member 5
chr13_+_41883137 Show fit	33.81	ENSRNOT00000004581	Slc35f5 NCBI RGD Ensembl Show fit	solute carrier family 35, member F5
chr1_-_198454914 Show fit	33.74	ENSRNOT00000049044	Prrt2 NCBI RGD Ensembl Show fit	proline-rich transmembrane protein 2
chr1_+_266530477 Show fit	33.67	ENSRNOT00000054699	Cnnm2 NCBI RGD Ensembl Show fit	cyclin and CBS domain divalent metal cation transport mediator 2
chr1_-_71290337 Show fit	33.59	ENSRNOT00000063956	Zfp667 NCBI RGD Ensembl Show fit	zinc finger protein 667
chr3_+_92969141 Show fit	33.57	ENSRNOT00000009797	Apip NCBI RGD Ensembl Show fit	APAF1 interacting protein
chr15_+_104095179 Show fit	33.24	ENSRNOT00000093487	Cldn10 NCBI RGD Ensembl Show fit	claudin 10
chr5_-_114014277 Show fit	33.14	ENSRNOT00000011731	Jun NCBI RGD Ensembl Show fit	Jun proto-oncogene, AP-1 transcription factor subunit
chr9_+_99998275 Show fit	33.07	ENSRNOT00000074395	Gpc1 NCBI RGD Ensembl Show fit	glypican 1
chr5_-_85123829 Show fit	32.96	ENSRNOT00000007578	Brinp1 NCBI RGD Ensembl Show fit	BMP/retinoic acid inducible neural specific 1
chr12_+_39553903 Show fit	32.90	ENSRNOT00000001738	Atp2a2 NCBI RGD Ensembl Show fit	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
chr8_-_94564525 Show fit	32.84	ENSRNOT00000084437	Snap91 NCBI RGD Ensembl Show fit	synaptosomal-associated protein 91
chr10_-_82887497 Show fit	32.77	ENSRNOT00000005644	Itga3 NCBI RGD Ensembl Show fit	integrin subunit alpha 3
chr1_+_101687855 Show fit	32.63	ENSRNOT00000028546 ENSRNOT00000091597	Dbp NCBI RGD Ensembl Show fit	D-box binding PAR bZIP transcription factor
chr2_-_250600517 Show fit	32.58	ENSRNOT00000016872	Hs2st1 NCBI RGD Ensembl Show fit	heparan sulfate 2-O-sulfotransferase 1
chr8_-_58293102 Show fit	32.39	ENSRNOT00000011913	Rab39a NCBI RGD Ensembl Show fit	RAB39A, member RAS oncogene family
chr2_+_22909569 Show fit	32.20	ENSRNOT00000073871	Homer1 NCBI RGD Ensembl Show fit	homer scaffolding protein 1
chrX_+_19243759 Show fit	32.14	ENSRNOT00000004238	Mageh1 NCBI RGD Ensembl Show fit	MAGE family member H1
chr19_-_9801942 Show fit	32.11	ENSRNOT00000051414 ENSRNOT00000017494	Ndrg4 NCBI RGD Ensembl Show fit	NDRG family member 4
chr9_-_83253458 Show fit	32.07	ENSRNOT00000041689	Epha4 NCBI RGD Ensembl Show fit	Eph receptor A4
chr10_+_74871523 Show fit	32.01	ENSRNOT00000076995 ENSRNOT00000076026 ENSRNOT00000088581 ENSRNOT00000076701	Sept4 NCBI RGD Ensembl Show fit	septin 4
chr18_+_83471342 Show fit	31.88	ENSRNOT00000019384	Neto1 NCBI RGD Ensembl Show fit	neuropilin and tolloid like 1
chr1_+_100393303 Show fit	31.81	ENSRNOT00000026251	Syt3 NCBI RGD Ensembl Show fit	synaptotagmin 3
chr10_+_56627411 Show fit	31.69	ENSRNOT00000089108 ENSRNOT00000068493	Dlg4 NCBI RGD Ensembl Show fit	discs large MAGUK scaffold protein 4
chr2_-_172459165 Show fit	31.55	ENSRNOT00000057473	Schip1 NCBI RGD Ensembl Show fit	schwannomin interacting protein 1
chr3_-_11382004 Show fit	31.52	ENSRNOT00000047921 ENSRNOT00000064039	Dnm1 NCBI RGD Ensembl Show fit	dynamin 1
chr18_-_57245666 Show fit	31.49	ENSRNOT00000080365	Ablim3 NCBI RGD Ensembl Show fit	actin binding LIM protein family, member 3
chr10_+_59585072 Show fit	31.37	ENSRNOT00000025009	Camkk1 NCBI RGD Ensembl Show fit	calcium/calmodulin-dependent protein kinase kinase 1
chr3_+_6773813 Show fit	31.30	ENSRNOT00000065953 ENSRNOT00000013443	Olfm1 NCBI RGD Ensembl Show fit	olfactomedin 1
chr2_+_85377318 Show fit	31.05	ENSRNOT00000016506 ENSRNOT00000085094	Sema5a NCBI RGD Ensembl Show fit	semaphorin 5A
chr7_-_116607674 Show fit	31.02	ENSRNOT00000076014	Ly6h NCBI RGD Ensembl Show fit	lymphocyte antigen 6 complex, locus H
chr5_+_138154673 Show fit	31.01	ENSRNOT00000064452	Slc2a1 NCBI RGD Ensembl Show fit	solute carrier family 2 member 1
chrX_+_37329779 Show fit	31.01	ENSRNOT00000038352 ENSRNOT00000088802	Pdha1 NCBI RGD Ensembl Show fit	pyruvate dehydrogenase (lipoamide) alpha 1
chr6_+_64297888 Show fit	30.86	ENSRNOT00000050222 ENSRNOT00000083088 ENSRNOT00000093147	Nrcam NCBI RGD Ensembl Show fit	neuronal cell adhesion molecule
chr14_+_114126943 Show fit	30.68	ENSRNOT00000041638 ENSRNOT00000006443 ENSRNOT00000006957	Rtn4 NCBI RGD Ensembl Show fit	reticulon 4
chr3_-_153893847 Show fit	30.47	ENSRNOT00000085938	LOC100911769 NCBI RGD Ensembl Show fit	band 4.1-like protein 1-like
chr12_+_39554171 Show fit	30.44	ENSRNOT00000024347	Atp2a2 NCBI RGD Ensembl Show fit	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
chr7_-_118396728 Show fit	30.42	ENSRNOT00000066431	Rbfox2 NCBI RGD Ensembl Show fit	RNA binding protein, fox-1 homolog 2
chr5_-_151709877 Show fit	30.38	ENSRNOT00000080602	Trnp1 NCBI RGD Ensembl Show fit	TMF1-regulated nuclear protein 1
chr2_+_225005019 Show fit	30.29	ENSRNOT00000015579	Cnn3 NCBI RGD Ensembl Show fit	calponin 3
chr10_-_104358253 Show fit	30.28	ENSRNOT00000005942	Caskin2 NCBI RGD Ensembl Show fit	cask-interacting protein 2
chr1_+_84067938 Show fit	29.84	ENSRNOT00000057213	Numbl NCBI RGD Ensembl Show fit	NUMB-like, endocytic adaptor protein
chr6_+_42180894 Show fit	29.72	ENSRNOT00000006403 ENSRNOT00000090816	Rock2 NCBI RGD Ensembl Show fit	Rho-associated coiled-coil containing protein kinase 2
chr1_-_100671074 Show fit	29.72	ENSRNOT00000027132	Myh14 NCBI RGD Ensembl Show fit	myosin heavy chain 14
chr2_-_166682325 Show fit	29.63	ENSRNOT00000091198 ENSRNOT00000012422	Sptssb NCBI RGD Ensembl Show fit	serine palmitoyltransferase, small subunit B
chr7_+_54980120 Show fit	29.58	ENSRNOT00000005690 ENSRNOT00000005773	Kcnc2 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily C member 2
chr1_-_72727112 Show fit	29.57	ENSRNOT00000031172	Brsk1 NCBI RGD Ensembl Show fit	BR serine/threonine kinase 1
chr16_+_20521956 Show fit	29.38	ENSRNOT00000026597	Pgpep1 NCBI RGD Ensembl Show fit	pyroglutamyl-peptidase I
chr11_-_68842320 Show fit	29.36	ENSRNOT00000049180	Adcy5 NCBI RGD Ensembl Show fit	adenylate cyclase 5
chr15_+_15275541 Show fit	29.34	ENSRNOT00000012153	Cadps NCBI RGD Ensembl Show fit	calcium dependent secretion activator
chr2_-_29768750 Show fit	29.29	ENSRNOT00000023460	Map1b NCBI RGD Ensembl Show fit	microtubule-associated protein 1B
chrX_+_63520991 Show fit	29.25	ENSRNOT00000071590	Apoo NCBI RGD Ensembl Show fit	apolipoprotein O
chr6_+_43001948 Show fit	29.16	ENSRNOT00000007374	Hpcal1 NCBI RGD Ensembl Show fit	hippocalcin-like 1
chr18_-_16497886 Show fit	29.11	ENSRNOT00000021624	Rprd1a NCBI RGD Ensembl Show fit	regulation of nuclear pre-mRNA domain containing 1A
chr1_+_39811314 Show fit	29.10	ENSRNOT00000022046	Ppp1r14c NCBI RGD Ensembl Show fit	protein phosphatase 1, regulatory (inhibitor) subunit 14c
chr14_+_36687134 Show fit	29.00	ENSRNOT00000002879	Usp46 NCBI RGD Ensembl Show fit	ubiquitin specific peptidase 46
chr7_-_105592804 Show fit	28.94	ENSRNOT00000006789	Adcy8 NCBI RGD Ensembl Show fit	adenylate cyclase 8
chr5_+_43603043 Show fit	28.78	ENSRNOT00000009899	Epha7 NCBI RGD Ensembl Show fit	Eph receptor A7
chr2_+_226900619 Show fit	28.72	ENSRNOT00000019638	Pde5a NCBI RGD Ensembl Show fit	phosphodiesterase 5A
chr20_+_5535432 Show fit	28.72	ENSRNOT00000040859	Syngap1 NCBI RGD Ensembl Show fit	synaptic Ras GTPase activating protein 1
chr3_-_149905944 Show fit	28.63	ENSRNOT00000021715	Snta1 NCBI RGD Ensembl Show fit	syntrophin, alpha 1
chr8_+_44847157 Show fit	28.60	ENSRNOT00000080288	Clmp NCBI RGD Ensembl Show fit	CXADR-like membrane protein
chr5_-_166259069 Show fit	28.58	ENSRNOT00000055572	Ube4b NCBI RGD Ensembl Show fit	ubiquitination factor E4B
chr13_-_111765944 Show fit	28.55	ENSRNOT00000073041	Syt14 NCBI RGD Ensembl Show fit	synaptotagmin 14
chrX_-_15707436 Show fit	28.54	ENSRNOT00000085907	Syp NCBI RGD Ensembl Show fit	synaptophysin
chr1_+_36320461 Show fit	28.53	ENSRNOT00000023659	Srd5a1 NCBI RGD Ensembl Show fit	steroid 5 alpha-reductase 1
chr12_+_37490584 Show fit	28.47	ENSRNOT00000001401 ENSRNOT00000090831	Rilpl1 NCBI RGD Ensembl Show fit	Rab interacting lysosomal protein-like 1
chr10_-_85684138 Show fit	28.43	ENSRNOT00000017989	Pip4k2b NCBI RGD Ensembl Show fit	phosphatidylinositol-5-phosphate 4-kinase type 2 beta
chr8_-_22821223 Show fit	28.30	ENSRNOT00000014135	Kank2 NCBI RGD Ensembl Show fit	KN motif and ankyrin repeat domains 2
chr6_+_43829945 Show fit	28.30	ENSRNOT00000086548	Klf11 NCBI RGD Ensembl Show fit	Kruppel-like factor 11
chr12_-_22211071 Show fit	28.27	ENSRNOT00000087817 ENSRNOT00000001910	Actl6b NCBI RGD Ensembl Show fit	actin-like 6B
chr12_+_23789638 Show fit	28.22	ENSRNOT00000001954 ENSRNOT00000084730	Ywhag NCBI RGD Ensembl Show fit	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
chrX_+_69730242 Show fit	28.18	ENSRNOT00000075980 ENSRNOT00000076425	Eda NCBI RGD Ensembl Show fit	ectodysplasin-A
chr4_+_44573264 Show fit	28.17	ENSRNOT00000080271	Cav2 NCBI RGD Ensembl Show fit	caveolin 2
chr7_-_116607408 Show fit	28.16	ENSRNOT00000076009 ENSRNOT00000056554	Ly6h NCBI RGD Ensembl Show fit	lymphocyte antigen 6 complex, locus H
chrX_-_134719097 Show fit	28.14	ENSRNOT00000068478	Smarca1 NCBI RGD Ensembl Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr12_+_15890170 Show fit	28.11	ENSRNOT00000001654	Gna12 NCBI RGD Ensembl Show fit	G protein subunit alpha 12
chr7_+_123381077 Show fit	28.01	ENSRNOT00000082603 ENSRNOT00000056041	Srebf2 NCBI RGD Ensembl Show fit	sterol regulatory element binding transcription factor 2
chr10_-_103826448 Show fit	27.92	ENSRNOT00000085636	Fdxr NCBI RGD Ensembl Show fit	ferredoxin reductase
chr19_+_20607507 Show fit	27.90	ENSRNOT00000000011	Cbln1 NCBI RGD Ensembl Show fit	cerebellin 1 precursor
chr1_+_221792221 Show fit	27.88	ENSRNOT00000054828	Nrxn2 NCBI RGD Ensembl Show fit	neurexin 2
chr6_+_76675418 Show fit	27.82	ENSRNOT00000076169 ENSRNOT00000010948 ENSRNOT00000082286	Brms1l NCBI RGD Ensembl Show fit Brms1l NCBI RGD Ensembl Show fit	breast cancer metastasis-suppressor 1-like breast cancer metastasis-suppressor 1-like
chrX_+_105573909 Show fit	27.80	ENSRNOT00000029664	Armcx3 NCBI RGD Ensembl Show fit	armadillo repeat containing, X-linked 3
chr1_-_64030175 Show fit	27.72	ENSRNOT00000089950	Tsen34l1 NCBI RGD Ensembl Show fit	tRNA splicing endonuclease subunit 34-like 1
chr15_-_44860604 Show fit	27.69	ENSRNOT00000018637	Nefm NCBI RGD Ensembl Show fit	neurofilament medium
chr8_+_128972311 Show fit	27.51	ENSRNOT00000025460	Myrip NCBI RGD Ensembl Show fit	myosin VIIA and Rab interacting protein
chr5_+_166464252 Show fit	27.48	ENSRNOT00000055562	Ctnnbip1 NCBI RGD Ensembl Show fit	catenin, beta-interacting protein 1
chr6_-_135829953 Show fit	27.45	ENSRNOT00000080623 ENSRNOT00000039059	Cdc42bpb NCBI RGD Ensembl Show fit	CDC42 binding protein kinase beta
chr3_+_2625015 Show fit	27.35	ENSRNOT00000018927	Npdc1 NCBI RGD Ensembl Show fit	neural proliferation, differentiation and control, 1
chr3_-_107760550 Show fit	27.28	ENSRNOT00000077091 ENSRNOT00000051638	Meis2 NCBI RGD Ensembl Show fit	Meis homeobox 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Sp1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
25.0	75.0	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
22.8	68.5	GO:1903422	negative regulation of synaptic vesicle recycling(GO:1903422)
22.5	67.4	GO:0033693	neurofilament bundle assembly(GO:0033693)
20.2	80.8	GO:0051582	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
19.1	57.2	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
18.9	37.9	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
18.9	56.6	GO:0060948	cardiac vascular smooth muscle cell development(GO:0060948)
17.4	52.2	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
17.2	68.8	GO:0090360	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
16.7	50.0	GO:0001966	thigmotaxis(GO:0001966)
16.6	66.4	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
16.5	82.7	GO:0050975	sensory perception of touch(GO:0050975)
15.6	62.5	GO:1904220	regulation of serine C-palmitoyltransferase activity(GO:1904220)
15.5	46.5	GO:1904457	positive regulation of neuronal action potential(GO:1904457)
15.5	62.0	GO:0007525	somatic muscle development(GO:0007525)
15.1	60.5	GO:0061534	gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
14.8	29.6	GO:1901079	positive regulation of relaxation of muscle(GO:1901079)
14.5	14.5	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
14.5	43.4	GO:0042822	pyridoxal phosphate metabolic process(GO:0042822)
14.5	86.8	GO:1902746	regulation of lens fiber cell differentiation(GO:1902746)
14.3	42.9	GO:0035607	ventricular zone neuroblast division(GO:0021847) fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development(GO:0035607) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
14.1	42.2	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
14.0	41.9	GO:0010643	cell communication by chemical coupling(GO:0010643)
13.9	41.6	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
13.8	96.9	GO:0016185	synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
13.8	13.8	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
13.7	41.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
13.4	67.2	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
13.3	40.0	GO:0006574	valine catabolic process(GO:0006574)
13.3	39.8	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
13.1	13.1	GO:0039526	suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host apoptotic process(GO:0039526)
13.0	130.4	GO:0036376	sodium ion export from cell(GO:0036376)
13.0	39.1	GO:1903445	protein transport from ciliary membrane to plasma membrane(GO:1903445)
13.0	117.3	GO:2001135	regulation of endocytic recycling(GO:2001135)
13.0	65.1	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
13.0	77.9	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
12.7	38.0	GO:0036500	ATF6-mediated unfolded protein response(GO:0036500)
12.6	37.8	GO:0046038	guanine salvage(GO:0006178) GMP catabolic process(GO:0046038) guanine biosynthetic process(GO:0046099)
12.4	62.1	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
12.4	74.1	GO:0010045	response to nickel cation(GO:0010045)
12.3	12.3	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
12.1	24.2	GO:0032423	regulation of mismatch repair(GO:0032423)
12.0	36.0	GO:1904685	positive regulation of metalloendopeptidase activity(GO:1904685)
11.9	35.7	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
11.8	35.4	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
11.7	35.2	GO:0019355	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
11.7	35.2	GO:1903566	ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
11.6	34.9	GO:0018201	peptidyl-glycine modification(GO:0018201)
11.5	23.0	GO:0002840	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
11.4	11.4	GO:0021836	chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
11.4	11.4	GO:1900673	olefin metabolic process(GO:1900673)
11.3	33.9	GO:0060082	eye blink reflex(GO:0060082)
11.3	45.2	GO:0010512	negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
11.3	45.2	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
11.3	67.7	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
10.9	32.6	GO:1904057	negative regulation of sensory perception of pain(GO:1904057)
10.7	64.3	GO:0006102	isocitrate metabolic process(GO:0006102)
10.7	53.5	GO:0023041	neuronal signal transduction(GO:0023041)
10.6	31.9	GO:2000312	regulation of kainate selective glutamate receptor activity(GO:2000312)
10.5	10.5	GO:0098917	retrograde trans-synaptic signaling(GO:0098917)
10.5	21.0	GO:0035711	T-helper 1 cell activation(GO:0035711)
10.5	31.4	GO:1902460	regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
10.4	31.1	GO:0098971	anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
10.2	40.9	GO:0072218	ascending thin limb development(GO:0072021) metanephric ascending thin limb development(GO:0072218)
10.2	71.5	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
10.2	40.6	GO:0097401	synaptic vesicle lumen acidification(GO:0097401)
10.0	30.1	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
9.9	29.8	GO:0021849	neuroblast division in subventricular zone(GO:0021849)
9.8	9.8	GO:0045763	negative regulation of cellular amino acid metabolic process(GO:0045763)
9.8	9.8	GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740)
9.8	126.9	GO:0046069	cGMP catabolic process(GO:0046069)
9.6	28.8	GO:1903847	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
9.6	86.3	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
9.6	57.5	GO:0048597	post-embryonic camera-type eye morphogenesis(GO:0048597)
9.6	19.2	GO:1900222	negative regulation of beta-amyloid clearance(GO:1900222)
9.5	28.6	GO:0003363	lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
9.5	28.6	GO:0038128	ERBB2 signaling pathway(GO:0038128)
9.5	38.0	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
9.5	28.4	GO:0032902	nerve growth factor production(GO:0032902)
9.4	37.7	GO:0021590	cerebellum maturation(GO:0021590)
9.4	28.2	GO:0061153	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
9.4	37.5	GO:0019042	viral latency(GO:0019042) release from viral latency(GO:0019046)
9.4	28.1	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
9.3	37.2	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
9.3	9.3	GO:2000137	negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137)
9.2	64.6	GO:0099525	presynaptic dense core granule exocytosis(GO:0099525)
9.2	9.2	GO:1903298	regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
9.2	46.0	GO:1990573	potassium ion import across plasma membrane(GO:1990573)
9.2	45.8	GO:0014053	negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
9.1	45.6	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
9.1	54.7	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
9.1	27.3	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
9.0	9.0	GO:0003273	cell migration involved in endocardial cushion formation(GO:0003273)
9.0	71.7	GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
8.9	17.9	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
8.8	17.6	GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
8.8	43.9	GO:0038030	non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
8.6	25.9	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
8.6	17.2	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
8.5	25.6	GO:0051933	amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
8.5	8.5	GO:0015744	succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
8.4	25.3	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
8.4	8.4	GO:0022615	protein to membrane docking(GO:0022615)
8.4	58.8	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
8.4	25.1	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
8.3	107.6	GO:0006527	arginine catabolic process(GO:0006527)
8.3	24.8	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
8.3	49.5	GO:0097113	AMPA glutamate receptor clustering(GO:0097113)
8.3	33.0	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
8.2	49.5	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
8.2	24.7	GO:0006543	glutamine catabolic process(GO:0006543)
8.2	24.6	GO:1904350	regulation of protein catabolic process in the vacuole(GO:1904350)
8.2	65.7	GO:0015866	ADP transport(GO:0015866)
8.2	16.4	GO:0010807	regulation of synaptic vesicle priming(GO:0010807)
8.1	16.3	GO:1900168	glial cell-derived neurotrophic factor secretion(GO:0044467) metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
8.1	40.7	GO:0019563	glycerol catabolic process(GO:0019563)
8.1	32.5	GO:0010615	positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
8.1	64.9	GO:0070294	renal sodium ion absorption(GO:0070294)
8.1	40.5	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
8.1	64.7	GO:0035934	corticosterone secretion(GO:0035934)
8.0	40.1	GO:0044800	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
8.0	24.1	GO:0030327	prenylated protein catabolic process(GO:0030327)
8.0	40.1	GO:0048852	diencephalon morphogenesis(GO:0048852)
8.0	24.1	GO:0019343	cysteine biosynthetic process via cystathionine(GO:0019343)
8.0	40.1	GO:0097242	beta-amyloid clearance(GO:0097242)
8.0	15.9	GO:1904708	granulosa cell apoptotic process(GO:1904700) regulation of granulosa cell apoptotic process(GO:1904708)
7.9	7.9	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
7.9	23.6	GO:0045751	regulation of Toll signaling pathway(GO:0008592) negative regulation of Toll signaling pathway(GO:0045751)
7.8	70.5	GO:0090385	phagosome-lysosome fusion(GO:0090385)
7.8	54.8	GO:0042420	dopamine catabolic process(GO:0042420)
7.8	15.5	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
7.8	15.5	GO:0046356	acetyl-CoA catabolic process(GO:0046356)
7.7	92.6	GO:0007614	short-term memory(GO:0007614)
7.7	7.7	GO:0051542	elastin biosynthetic process(GO:0051542)
7.6	38.0	GO:0061743	motor learning(GO:0061743)
7.6	22.8	GO:2000437	regulation of monocyte extravasation(GO:2000437)
7.6	22.8	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
7.6	53.1	GO:0045964	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
7.6	37.9	GO:0006382	adenosine to inosine editing(GO:0006382)
7.5	45.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
7.5	22.6	GO:2000474	regulation of opioid receptor signaling pathway(GO:2000474)
7.5	22.5	GO:0032915	positive regulation of transforming growth factor beta2 production(GO:0032915)
7.4	22.3	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
7.4	14.9	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
7.3	29.3	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
7.3	36.5	GO:0002159	desmosome assembly(GO:0002159)
7.3	7.3	GO:0060454	positive regulation of gastric acid secretion(GO:0060454)
7.3	7.3	GO:2000463	positive regulation of excitatory postsynaptic potential(GO:2000463)
7.3	58.0	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
7.2	21.7	GO:0071877	regulation of adrenergic receptor signaling pathway(GO:0071877)
7.2	21.6	GO:0046952	ketone body catabolic process(GO:0046952)
7.2	43.1	GO:0045329	carnitine biosynthetic process(GO:0045329)
7.2	43.0	GO:1900034	regulation of cellular response to heat(GO:1900034)
7.1	14.2	GO:0051612	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
7.1	28.4	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
7.1	21.3	GO:0071529	cementum mineralization(GO:0071529)
7.1	42.5	GO:0046959	habituation(GO:0046959)
7.1	70.7	GO:0071874	cellular response to norepinephrine stimulus(GO:0071874)
7.1	35.3	GO:0048842	positive regulation of axon extension involved in axon guidance(GO:0048842)
7.0	7.0	GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
7.0	21.1	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
7.0	42.2	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
7.0	7.0	GO:1901219	regulation of cardiac chamber morphogenesis(GO:1901219) negative regulation of cardiac chamber morphogenesis(GO:1901220)
6.9	13.9	GO:0046958	nonassociative learning(GO:0046958)
6.9	55.5	GO:0097623	potassium ion export across plasma membrane(GO:0097623)
6.9	34.7	GO:0051964	negative regulation of synapse assembly(GO:0051964)
6.9	6.9	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
6.9	27.7	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
6.9	20.8	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
6.9	90.0	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
6.9	76.1	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
6.9	55.3	GO:0015871	choline transport(GO:0015871)
6.9	34.4	GO:0097116	gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
6.8	13.7	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
6.8	20.4	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
6.8	20.3	GO:0060279	positive regulation of ovulation(GO:0060279)
6.7	27.0	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
6.7	20.1	GO:0090272	negative regulation of fibroblast growth factor production(GO:0090272)
6.7	80.3	GO:0001886	endothelial cell morphogenesis(GO:0001886)
6.7	40.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
6.7	13.3	GO:0060300	regulation of cytokine activity(GO:0060300)
6.7	46.6	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
6.6	26.6	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
6.6	6.6	GO:1904835	vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
6.6	92.7	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
6.6	19.9	GO:0099552	trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
6.6	26.3	GO:0021586	pons maturation(GO:0021586)
6.6	19.7	GO:0035992	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
6.6	26.2	GO:0097091	synaptic vesicle clustering(GO:0097091)
6.5	45.8	GO:0097084	vascular smooth muscle cell development(GO:0097084)
6.5	19.6	GO:0019541	acetate metabolic process(GO:0006083) propionate metabolic process(GO:0019541)
6.5	19.6	GO:0032304	negative regulation of icosanoid secretion(GO:0032304)
6.5	32.5	GO:0061034	olfactory bulb mitral cell layer development(GO:0061034)
6.5	19.5	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
6.5	25.9	GO:0042126	nitrate metabolic process(GO:0042126)
6.5	25.9	GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
6.4	32.2	GO:0044691	tooth eruption(GO:0044691)
6.4	19.2	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
6.4	6.4	GO:0070370	cellular heat acclimation(GO:0070370)
6.4	6.4	GO:0072554	blood vessel lumenization(GO:0072554)
6.4	25.5	GO:0060594	mammary gland specification(GO:0060594)
6.4	19.1	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
6.4	25.4	GO:0032264	IMP salvage(GO:0032264)
6.3	6.3	GO:1903903	regulation of establishment of T cell polarity(GO:1903903)
6.3	19.0	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
6.3	19.0	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
6.3	44.2	GO:0061621	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
6.3	12.6	GO:0021697	cerebellar cortex formation(GO:0021697)
6.2	18.7	GO:0010796	regulation of multivesicular body size(GO:0010796)
6.2	18.7	GO:0055129	L-proline biosynthetic process(GO:0055129)
6.2	24.9	GO:0097104	postsynaptic membrane assembly(GO:0097104)
6.2	18.6	GO:0001661	conditioned taste aversion(GO:0001661)
6.2	92.9	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
6.2	24.8	GO:0060023	soft palate development(GO:0060023)
6.1	24.6	GO:0060857	establishment of glial blood-brain barrier(GO:0060857)
6.1	6.1	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
6.1	18.2	GO:2000328	regulation of T-helper 17 cell lineage commitment(GO:2000328)
6.1	85.0	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
6.0	24.2	GO:0038027	apolipoprotein A-I-mediated signaling pathway(GO:0038027)
6.0	42.3	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
6.0	12.1	GO:0016094	polyprenol biosynthetic process(GO:0016094)
6.0	18.0	GO:0035095	behavioral response to nicotine(GO:0035095)
6.0	12.0	GO:0090210	regulation of establishment of blood-brain barrier(GO:0090210)
6.0	11.9	GO:1903721	regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
6.0	17.9	GO:0036414	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
6.0	11.9	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
5.9	29.7	GO:0016081	synaptic vesicle docking(GO:0016081)
5.9	23.8	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
5.9	17.8	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
5.9	23.7	GO:0098886	modification of dendritic spine(GO:0098886)
5.9	17.7	GO:0006713	glucocorticoid catabolic process(GO:0006713)
5.9	35.2	GO:0021759	globus pallidus development(GO:0021759)
5.9	35.2	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
5.9	5.9	GO:1904056	regulation of cholangiocyte proliferation(GO:1904054) positive regulation of cholangiocyte proliferation(GO:1904056)
5.9	11.7	GO:0006116	NADH oxidation(GO:0006116)
5.8	17.4	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
5.8	63.8	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
5.8	11.6	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
5.8	34.7	GO:0010968	regulation of microtubule nucleation(GO:0010968)
5.8	5.8	GO:0031161	phosphatidylinositol catabolic process(GO:0031161)
5.8	17.3	GO:0048550	negative regulation of pinocytosis(GO:0048550)
5.8	17.3	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
5.7	68.8	GO:0021707	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
5.7	45.8	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
5.7	11.4	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
5.7	22.8	GO:1903059	regulation of protein lipidation(GO:1903059)
5.7	5.7	GO:1902837	amino acid import into cell(GO:1902837)
5.7	17.0	GO:0006214	thymidine catabolic process(GO:0006214) pyrimidine deoxyribonucleoside catabolic process(GO:0046127)
5.7	22.6	GO:0060022	hard palate development(GO:0060022)
5.7	5.7	GO:0010996	response to auditory stimulus(GO:0010996)
5.6	33.7	GO:0035900	response to isolation stress(GO:0035900)
5.6	11.2	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
5.5	5.5	GO:0055064	chloride ion homeostasis(GO:0055064)
5.5	5.5	GO:0006680	glucosylceramide catabolic process(GO:0006680)
5.5	16.4	GO:0000189	MAPK import into nucleus(GO:0000189)
5.5	5.5	GO:0009644	response to high light intensity(GO:0009644)
5.4	5.4	GO:0009093	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
5.4	32.6	GO:0042908	xenobiotic transport(GO:0042908)
5.4	16.3	GO:0060988	lipid tube assembly(GO:0060988)
5.4	43.2	GO:0006021	inositol biosynthetic process(GO:0006021)
5.4	16.2	GO:0051036	regulation of endosome size(GO:0051036)
5.4	16.2	GO:0090504	wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
5.4	10.8	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
5.4	21.5	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
5.4	21.5	GO:0015746	citrate transport(GO:0015746)
5.4	10.8	GO:1900126	regulation of hyaluronan biosynthetic process(GO:1900125) negative regulation of hyaluronan biosynthetic process(GO:1900126)
5.4	21.5	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
5.4	16.1	GO:2001045	negative regulation of integrin-mediated signaling pathway(GO:2001045)
5.4	21.4	GO:0036394	amylase secretion(GO:0036394)
5.4	5.4	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
5.4	5.4	GO:1905244	regulation of modification of synaptic structure(GO:1905244)
5.3	21.4	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
5.3	74.5	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
5.3	15.9	GO:0035989	tendon development(GO:0035989)
5.3	126.4	GO:2000300	regulation of synaptic vesicle exocytosis(GO:2000300)
5.3	21.0	GO:0019074	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
5.3	5.3	GO:0003365	establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
5.3	15.8	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
5.2	5.2	GO:0061526	acetylcholine secretion(GO:0061526)
5.2	52.1	GO:0070995	NADPH oxidation(GO:0070995)
5.2	5.2	GO:1903243	negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
5.2	10.4	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
5.2	26.0	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
5.2	36.1	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128)
5.1	15.4	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
5.1	30.9	GO:0071318	cellular response to ATP(GO:0071318)
5.1	20.6	GO:0046083	adenine metabolic process(GO:0046083)
5.1	15.4	GO:1902869	regulation of amacrine cell differentiation(GO:1902869)
5.1	20.5	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
5.1	15.3	GO:0002447	eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
5.1	20.4	GO:1990791	dorsal root ganglion development(GO:1990791)
5.1	5.1	GO:0072161	mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
5.1	20.3	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
5.1	15.2	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
5.1	15.2	GO:0010133	proline catabolic process to glutamate(GO:0010133)
5.0	65.5	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
5.0	15.1	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
5.0	50.3	GO:0001977	renal system process involved in regulation of blood volume(GO:0001977)
5.0	181.1	GO:0046928	regulation of neurotransmitter secretion(GO:0046928)
5.0	55.2	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
5.0	70.3	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
5.0	205.2	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
5.0	40.0	GO:0042747	circadian sleep/wake cycle, REM sleep(GO:0042747)
5.0	44.9	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
5.0	24.8	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
5.0	29.8	GO:0099526	presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
5.0	29.8	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
4.9	14.8	GO:2001160	regulation of histone H3-K79 methylation(GO:2001160)
4.9	14.8	GO:0006741	NADP biosynthetic process(GO:0006741)
4.9	4.9	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
4.9	133.1	GO:0007212	dopamine receptor signaling pathway(GO:0007212)
4.9	93.4	GO:0031581	hemidesmosome assembly(GO:0031581)
4.9	24.6	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
4.9	24.6	GO:0051182	coenzyme transport(GO:0051182)
4.9	9.8	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
4.9	63.6	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
4.9	39.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
4.9	4.9	GO:0070315	G1 to G0 transition involved in cell differentiation(GO:0070315)
4.9	68.1	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
4.9	14.6	GO:0021698	cerebellar cortex structural organization(GO:0021698)
4.9	19.4	GO:1904616	regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
4.8	33.9	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
4.8	19.4	GO:0030043	actin filament fragmentation(GO:0030043)
4.8	19.4	GO:0032097	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
4.8	4.8	GO:1904313	response to methamphetamine hydrochloride(GO:1904313)
4.8	4.8	GO:0033864	positive regulation of NAD(P)H oxidase activity(GO:0033864)
4.8	28.9	GO:0045792	negative regulation of cell size(GO:0045792)
4.8	62.7	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
4.8	9.6	GO:2001055	activation of meiosis(GO:0090427) positive regulation of mesenchymal cell apoptotic process(GO:2001055)
4.8	19.3	GO:1904428	negative regulation of tubulin deacetylation(GO:1904428)
4.8	14.4	GO:0089712	L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
4.8	4.8	GO:0060057	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
4.8	4.8	GO:0034760	negative regulation of iron ion transmembrane transport(GO:0034760)
4.8	19.2	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
4.8	9.6	GO:0097037	heme export(GO:0097037)
4.8	28.7	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
4.8	14.3	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
4.8	42.9	GO:1900273	positive regulation of long-term synaptic potentiation(GO:1900273)
4.8	38.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
4.7	9.5	GO:0006011	UDP-glucose metabolic process(GO:0006011)
4.7	33.0	GO:0030050	vesicle transport along actin filament(GO:0030050)
4.7	14.1	GO:0042756	drinking behavior(GO:0042756)
4.7	89.2	GO:0095500	acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
4.7	32.8	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
4.7	9.4	GO:0035625	receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
4.7	14.1	GO:0016128	phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
4.7	14.0	GO:0003383	apical constriction(GO:0003383)
4.7	51.3	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
4.6	18.6	GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
4.6	13.9	GO:0099640	axo-dendritic protein transport(GO:0099640)
4.6	23.2	GO:2000785	regulation of autophagosome assembly(GO:2000785)
4.6	73.8	GO:1903861	positive regulation of dendrite extension(GO:1903861)
4.6	23.0	GO:0060014	granulosa cell differentiation(GO:0060014)
4.6	4.6	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
4.6	55.1	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
4.6	9.1	GO:0099601	regulation of neurotransmitter receptor activity(GO:0099601)
4.6	13.7	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
4.6	22.8	GO:0015865	purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
4.5	22.7	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
4.5	9.0	GO:0021943	formation of radial glial scaffolds(GO:0021943)
4.5	9.0	GO:0009136	purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
4.5	9.0	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
4.5	13.5	GO:1904578	response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
4.5	27.0	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
4.5	9.0	GO:1904045	cellular response to aldosterone(GO:1904045)
4.5	4.5	GO:0051589	negative regulation of neurotransmitter transport(GO:0051589)
4.5	8.9	GO:0032849	positive regulation of cellular pH reduction(GO:0032849)
4.5	133.6	GO:0034260	negative regulation of GTPase activity(GO:0034260)
4.5	17.8	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
4.4	26.7	GO:0021696	cerebellar cortex morphogenesis(GO:0021696)
4.4	13.3	GO:0003057	regulation of the force of heart contraction by chemical signal(GO:0003057)
4.4	30.9	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
4.4	8.8	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
4.4	13.2	GO:0097187	dentinogenesis(GO:0097187)
4.4	13.2	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
4.4	39.4	GO:1900746	regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
4.4	39.2	GO:0060013	righting reflex(GO:0060013)
4.3	17.3	GO:0045634	regulation of melanocyte differentiation(GO:0045634) positive regulation of melanocyte differentiation(GO:0045636)
4.3	25.9	GO:2000823	regulation of androgen receptor activity(GO:2000823)
4.3	4.3	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
4.3	4.3	GO:1990051	activation of protein kinase C activity(GO:1990051)
4.3	17.2	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
4.3	34.3	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
4.3	55.6	GO:0072525	pyridine-containing compound biosynthetic process(GO:0072525)
4.3	12.8	GO:0035928	rRNA import into mitochondrion(GO:0035928)
4.3	4.3	GO:0048549	positive regulation of pinocytosis(GO:0048549)
4.2	8.5	GO:0032286	central nervous system myelin maintenance(GO:0032286)
4.2	17.0	GO:0030382	sperm mitochondrion organization(GO:0030382)
4.2	16.9	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
4.2	12.7	GO:0016487	sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
4.2	29.4	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
4.2	8.4	GO:1905077	regulation of interleukin-17 secretion(GO:1905076) negative regulation of interleukin-17 secretion(GO:1905077)
4.2	25.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
4.2	12.5	GO:0010625	positive regulation of Schwann cell proliferation(GO:0010625)
4.2	4.2	GO:0036089	cleavage furrow formation(GO:0036089)
4.2	12.5	GO:0072720	response to dithiothreitol(GO:0072720)
4.2	16.6	GO:1905150	regulation of voltage-gated sodium channel activity(GO:1905150)
4.1	29.0	GO:0006703	estrogen biosynthetic process(GO:0006703)
4.1	70.4	GO:0006895	Golgi to endosome transport(GO:0006895)
4.1	12.4	GO:0036486	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
4.1	20.7	GO:0002035	brain renin-angiotensin system(GO:0002035)
4.1	20.7	GO:0034553	respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
4.1	12.4	GO:0015824	proline transport(GO:0015824) proline transmembrane transport(GO:0035524)
4.1	33.1	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
4.1	12.4	GO:0042125	protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
4.1	12.3	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
4.1	8.2	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
4.1	4.1	GO:0042713	sperm ejaculation(GO:0042713)
4.1	77.7	GO:0009251	glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
4.1	44.9	GO:0032482	Rab protein signal transduction(GO:0032482)
4.1	12.3	GO:0021740	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
4.1	85.7	GO:0001553	luteinization(GO:0001553)
4.1	28.6	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
4.1	8.2	GO:0009106	lipoate metabolic process(GO:0009106)
4.1	12.2	GO:0072734	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
4.0	16.2	GO:1902732	positive regulation of chondrocyte proliferation(GO:1902732)
4.0	32.3	GO:0015884	folic acid transport(GO:0015884)
4.0	20.1	GO:0072093	metanephric renal vesicle formation(GO:0072093)
4.0	12.1	GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
4.0	28.2	GO:0071340	skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
4.0	32.1	GO:0033690	positive regulation of osteoblast proliferation(GO:0033690)
4.0	84.1	GO:0021680	cerebellar Purkinje cell layer development(GO:0021680)
4.0	32.0	GO:0035865	cellular response to potassium ion(GO:0035865)
4.0	16.0	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
4.0	4.0	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
4.0	4.0	GO:0072237	metanephric proximal tubule development(GO:0072237)
4.0	12.0	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
4.0	7.9	GO:0035544	negative regulation of SNARE complex assembly(GO:0035544)
4.0	7.9	GO:0090520	sphingolipid mediated signaling pathway(GO:0090520)
4.0	11.9	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
3.9	7.9	GO:0032380	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
3.9	11.8	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
3.9	43.4	GO:0006086	acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
3.9	7.9	GO:0070560	protein secretion by platelet(GO:0070560)
3.9	47.2	GO:1904259	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
3.9	15.6	GO:0032486	Rap protein signal transduction(GO:0032486)
3.9	57.8	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
3.8	42.3	GO:0061162	establishment of monopolar cell polarity(GO:0061162)
3.8	7.6	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
3.8	22.9	GO:0098885	modification of postsynaptic actin cytoskeleton(GO:0098885)
3.8	22.9	GO:0033564	anterior/posterior axon guidance(GO:0033564)
3.8	11.4	GO:0034499	late endosome to Golgi transport(GO:0034499)
3.8	26.7	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
3.8	15.2	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
3.8	22.7	GO:0010044	response to aluminum ion(GO:0010044)
3.8	68.1	GO:0021859	pyramidal neuron differentiation(GO:0021859)
3.8	11.3	GO:1901873	regulation of post-translational protein modification(GO:1901873)
3.8	15.1	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
3.8	48.9	GO:0016486	peptide hormone processing(GO:0016486)
3.8	15.0	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
3.7	3.7	GO:0014044	Schwann cell development(GO:0014044)
3.7	7.5	GO:0014042	positive regulation of neuron maturation(GO:0014042)
3.7	56.1	GO:0014002	astrocyte development(GO:0014002)
3.7	7.5	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
3.7	37.3	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
3.7	3.7	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
3.7	14.9	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
3.7	7.4	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
3.7	14.8	GO:0009822	alkaloid catabolic process(GO:0009822)
3.7	25.9	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
3.7	7.4	GO:0038003	opioid receptor signaling pathway(GO:0038003)
3.7	7.4	GO:0070541	response to platinum ion(GO:0070541)
3.7	3.7	GO:0010877	lipid transport involved in lipid storage(GO:0010877)
3.7	33.0	GO:0071985	multivesicular body sorting pathway(GO:0071985)
3.7	7.3	GO:0021892	cerebral cortex GABAergic interneuron differentiation(GO:0021892)
3.6	7.3	GO:0045054	constitutive secretory pathway(GO:0045054)
3.6	3.6	GO:0007412	axon target recognition(GO:0007412)
3.6	10.8	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
3.6	18.0	GO:0097211	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
3.6	28.8	GO:0071294	cellular response to zinc ion(GO:0071294)
3.6	50.2	GO:0071625	vocalization behavior(GO:0071625)
3.6	10.8	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
3.6	7.2	GO:0009992	cellular water homeostasis(GO:0009992)
3.6	21.5	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
3.6	35.7	GO:0010040	response to iron(II) ion(GO:0010040)
3.6	25.0	GO:0016198	axon choice point recognition(GO:0016198)
3.6	39.2	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
3.6	10.7	GO:0071431	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
3.5	7.1	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
3.5	3.5	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
3.5	10.6	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
3.5	17.5	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
3.5	21.0	GO:0038203	TORC2 signaling(GO:0038203)
3.5	3.5	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
3.5	31.5	GO:0060081	membrane hyperpolarization(GO:0060081)
3.5	7.0	GO:0072199	mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199)
3.5	6.9	GO:2000467	positive regulation of glycogen (starch) synthase activity(GO:2000467)
3.5	10.4	GO:0048749	compound eye development(GO:0048749)
3.5	20.8	GO:0048496	maintenance of organ identity(GO:0048496)
3.5	17.3	GO:0045026	plasma membrane fusion(GO:0045026)
3.5	34.5	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
3.4	13.7	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
3.4	13.7	GO:0098961	dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
3.4	6.9	GO:1902965	regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
3.4	92.4	GO:0036465	synaptic vesicle recycling(GO:0036465)
3.4	47.7	GO:0042407	cristae formation(GO:0042407)
3.4	6.8	GO:0015827	tryptophan transport(GO:0015827)
3.4	10.2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
3.4	6.8	GO:0060120	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
3.4	16.9	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
3.4	13.5	GO:0042853	L-alanine catabolic process(GO:0042853)
3.4	13.5	GO:1902617	response to fluoride(GO:1902617)
3.4	13.5	GO:2000501	natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
3.4	30.2	GO:0002028	regulation of sodium ion transport(GO:0002028)
3.3	26.7	GO:0051181	cofactor transport(GO:0051181)
3.3	13.3	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
3.3	10.0	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
3.3	13.3	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
3.3	3.3	GO:0006107	oxaloacetate metabolic process(GO:0006107)
3.3	3.3	GO:1903056	regulation of melanosome organization(GO:1903056)
3.3	19.9	GO:0018344	protein geranylgeranylation(GO:0018344)
3.3	16.5	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
3.3	3.3	GO:0007386	compartment pattern specification(GO:0007386)
3.3	6.6	GO:2000650	negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
3.3	3.3	GO:0006842	tricarboxylic acid transport(GO:0006842)
3.3	62.4	GO:0007035	vacuolar acidification(GO:0007035)
3.3	9.9	GO:0042746	regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
3.3	23.0	GO:0000103	sulfate assimilation(GO:0000103)
3.3	22.9	GO:0050884	neuromuscular process controlling posture(GO:0050884)
3.3	9.8	GO:1990166	protein localization to site of double-strand break(GO:1990166)
3.3	19.5	GO:0038084	vascular endothelial growth factor signaling pathway(GO:0038084)
3.2	9.7	GO:0030091	protein repair(GO:0030091)
3.2	32.0	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
3.2	9.6	GO:0038172	interleukin-33-mediated signaling pathway(GO:0038172)
3.2	9.6	GO:0016267	O-glycan processing, core 1(GO:0016267)
3.2	6.4	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
3.2	9.5	GO:0018199	peptidyl-glutamine modification(GO:0018199)
3.2	12.7	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
3.2	9.5	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
3.2	3.2	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
3.2	34.8	GO:0007258	JUN phosphorylation(GO:0007258)
3.2	9.5	GO:0036118	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
3.1	18.8	GO:0001921	positive regulation of receptor recycling(GO:0001921)
3.1	9.4	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
3.1	18.7	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
3.1	9.3	GO:0070445	oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
3.1	52.9	GO:0090161	Golgi ribbon formation(GO:0090161)
3.1	9.3	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
3.1	6.2	GO:1900368	regulation of RNA interference(GO:1900368)
3.1	6.2	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
3.1	18.5	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
3.1	24.7	GO:0007416	synapse assembly(GO:0007416)
3.1	12.3	GO:0006004	fucose metabolic process(GO:0006004)
3.1	3.1	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
3.1	3.1	GO:0002731	negative regulation of dendritic cell cytokine production(GO:0002731)
3.1	12.3	GO:0035523	protein K29-linked deubiquitination(GO:0035523)
3.1	70.3	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
3.1	6.1	GO:0019934	cGMP-mediated signaling(GO:0019934)
3.0	57.9	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
3.0	36.4	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
3.0	15.1	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
3.0	18.2	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
3.0	48.3	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
3.0	15.1	GO:1990034	calcium ion export from cell(GO:1990034)
3.0	21.0	GO:0014010	Schwann cell proliferation(GO:0014010)
3.0	21.0	GO:0006108	malate metabolic process(GO:0006108)
3.0	9.0	GO:0072695	negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
3.0	8.9	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
3.0	20.8	GO:0032328	alanine transport(GO:0032328)
3.0	20.7	GO:0019388	galactose catabolic process(GO:0019388)
3.0	17.7	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
2.9	5.9	GO:1901620	regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
2.9	8.8	GO:0051012	microtubule sliding(GO:0051012)
2.9	11.8	GO:0021535	cell migration in hindbrain(GO:0021535)
2.9	8.8	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
2.9	11.7	GO:1904923	regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
2.9	17.5	GO:0003310	pancreatic A cell differentiation(GO:0003310)
2.9	5.8	GO:1990792	response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
2.9	11.7	GO:0021794	thalamus development(GO:0021794)
2.9	23.3	GO:0031643	positive regulation of myelination(GO:0031643)
2.9	14.5	GO:0035754	B cell chemotaxis(GO:0035754)
2.9	11.6	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
2.9	14.4	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
2.9	2.9	GO:0086009	membrane repolarization(GO:0086009)
2.9	17.3	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
2.9	11.5	GO:0097119	postsynaptic density protein 95 clustering(GO:0097119)
2.9	22.9	GO:0032292	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
2.9	14.3	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
2.9	31.4	GO:0007252	I-kappaB phosphorylation(GO:0007252)
2.9	8.6	GO:0042373	vitamin K metabolic process(GO:0042373)
2.8	8.5	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
2.8	11.3	GO:0090394	negative regulation of excitatory postsynaptic potential(GO:0090394)
2.8	8.5	GO:0009597	detection of virus(GO:0009597)
2.8	14.2	GO:0042135	neurotransmitter catabolic process(GO:0042135)
2.8	14.1	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
2.8	25.4	GO:1900078	positive regulation of cellular response to insulin stimulus(GO:1900078)
2.8	61.9	GO:0097503	sialylation(GO:0097503)
2.8	45.0	GO:0007413	axonal fasciculation(GO:0007413)
2.8	14.0	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
2.8	30.8	GO:0001573	ganglioside metabolic process(GO:0001573)
2.8	19.5	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
2.8	5.6	GO:0046351	disaccharide biosynthetic process(GO:0046351)
2.8	8.3	GO:0098937	dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
2.8	8.3	GO:0042489	negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
2.8	13.8	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
2.8	8.3	GO:0044027	hypermethylation of CpG island(GO:0044027)
2.8	8.3	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
2.7	16.5	GO:0033623	regulation of integrin activation(GO:0033623)
2.7	2.7	GO:1902730	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
2.7	13.7	GO:0070305	response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
2.7	5.5	GO:0009957	epidermal cell fate specification(GO:0009957) response to chlorate(GO:0010157)
2.7	21.9	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
2.7	24.6	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
2.7	35.2	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
2.7	8.1	GO:0098779	mitophagy in response to mitochondrial depolarization(GO:0098779)
2.7	8.1	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
2.7	5.4	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
2.7	8.1	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
2.7	8.1	GO:0045210	FasL biosynthetic process(GO:0045210)
2.7	8.1	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
2.7	13.4	GO:0023021	termination of signal transduction(GO:0023021)
2.7	18.8	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
2.7	16.1	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
2.7	34.8	GO:0051058	negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
2.7	26.7	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
2.7	37.3	GO:0032469	endoplasmic reticulum calcium ion homeostasis(GO:0032469)
2.7	10.6	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
2.7	26.6	GO:0032780	negative regulation of ATPase activity(GO:0032780)
2.7	8.0	GO:0071461	cellular response to redox state(GO:0071461)
2.7	10.6	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
2.6	7.9	GO:0002084	protein depalmitoylation(GO:0002084)
2.6	15.8	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
2.6	2.6	GO:0006085	acetyl-CoA biosynthetic process(GO:0006085)
2.6	5.2	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
2.6	5.2	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
2.6	7.8	GO:2000687	negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
2.6	2.6	GO:0032530	regulation of microvillus organization(GO:0032530)
2.6	7.8	GO:0045959	negative regulation of complement activation, classical pathway(GO:0045959)
2.6	10.4	GO:0032919	spermine acetylation(GO:0032919)
2.6	5.2	GO:0090261	positive regulation of inclusion body assembly(GO:0090261)
2.6	2.6	GO:0072276	metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
2.6	7.7	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
2.6	7.7	GO:0006106	fumarate metabolic process(GO:0006106)
2.6	7.7	GO:1904424	regulation of GTP binding(GO:1904424)
2.6	10.2	GO:0035772	interleukin-13-mediated signaling pathway(GO:0035772)
2.5	12.7	GO:0052428	negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
2.5	15.2	GO:0097039	protein linear polyubiquitination(GO:0097039)
2.5	10.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
2.5	5.1	GO:0046947	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
2.5	10.1	GO:0033622	integrin activation(GO:0033622)
2.5	17.5	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
2.5	7.5	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
2.5	25.0	GO:0016926	protein desumoylation(GO:0016926)
2.5	22.3	GO:0035493	SNARE complex assembly(GO:0035493)
2.5	7.4	GO:2000628	regulation of miRNA metabolic process(GO:2000628)
2.5	14.8	GO:0045196	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
2.4	9.8	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
2.4	4.9	GO:0015693	magnesium ion transport(GO:0015693)
2.4	7.3	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
2.4	36.5	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
2.4	7.3	GO:0042494	detection of bacterial lipoprotein(GO:0042494)
2.4	7.3	GO:0072086	specification of loop of Henle identity(GO:0072086)
2.4	17.0	GO:1902414	protein localization to cell junction(GO:1902414)
2.4	7.3	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
2.4	7.3	GO:0006667	sphinganine metabolic process(GO:0006667)
2.4	7.2	GO:0021564	vagus nerve development(GO:0021564)
2.4	93.8	GO:0006635	fatty acid beta-oxidation(GO:0006635)
2.4	16.8	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
2.4	9.6	GO:0045112	integrin biosynthetic process(GO:0045112)
2.4	4.8	GO:0033687	osteoblast proliferation(GO:0033687)
2.4	26.3	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
2.4	14.3	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
2.4	4.8	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
2.4	4.7	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
2.4	4.7	GO:0001552	ovarian follicle atresia(GO:0001552)
2.4	9.5	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
2.4	7.1	GO:0035522	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
2.4	4.7	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
2.4	4.7	GO:0035973	aggrephagy(GO:0035973)
2.4	11.8	GO:0046710	GDP metabolic process(GO:0046710)
2.3	9.4	GO:0090493	catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
2.3	11.7	GO:0040016	embryonic cleavage(GO:0040016)
2.3	7.0	GO:0051968	positive regulation of synaptic transmission, glutamatergic(GO:0051968)
2.3	4.7	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
2.3	9.3	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
2.3	76.8	GO:0035136	forelimb morphogenesis(GO:0035136)
2.3	16.3	GO:0006465	signal peptide processing(GO:0006465)
2.3	11.6	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
2.3	6.9	GO:0010265	SCF complex assembly(GO:0010265)
2.3	62.2	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
2.3	9.2	GO:0071673	positive regulation of smooth muscle cell chemotaxis(GO:0071673)
2.3	6.9	GO:0009758	carbohydrate utilization(GO:0009758)
2.3	57.3	GO:0019835	cytolysis(GO:0019835)
2.3	9.2	GO:0031642	negative regulation of myelination(GO:0031642)
2.3	6.9	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
2.3	64.0	GO:1904659	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
2.3	4.6	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
2.3	4.6	GO:0014045	establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
2.3	4.6	GO:0018410	C-terminal protein amino acid modification(GO:0018410)
2.3	6.8	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
2.3	6.8	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
2.3	13.6	GO:0006600	creatine metabolic process(GO:0006600)
2.3	13.5	GO:0098780	response to mitochondrial depolarisation(GO:0098780)
2.2	4.5	GO:0090335	regulation of brown fat cell differentiation(GO:0090335)
2.2	9.0	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
2.2	15.7	GO:0009134	nucleoside diphosphate catabolic process(GO:0009134)
2.2	4.5	GO:0042851	L-alanine metabolic process(GO:0042851)
2.2	24.4	GO:0086016	AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
2.2	75.5	GO:0046839	phospholipid dephosphorylation(GO:0046839)
2.2	6.6	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
2.2	17.6	GO:0048484	enteric nervous system development(GO:0048484)
2.2	8.7	GO:0044778	meiotic DNA integrity checkpoint(GO:0044778)
2.2	8.7	GO:0018158	protein oxidation(GO:0018158)
2.2	2.2	GO:0019371	cyclooxygenase pathway(GO:0019371)
2.2	4.4	GO:0060492	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
2.2	8.7	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
2.2	4.3	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
2.2	30.2	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
2.2	4.3	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
2.2	10.8	GO:0042745	circadian sleep/wake cycle(GO:0042745)
2.1	4.3	GO:1904674	positive regulation of somatic stem cell population maintenance(GO:1904674)
2.1	4.3	GO:0006710	androgen catabolic process(GO:0006710)
2.1	12.8	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
2.1	10.7	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
2.1	95.8	GO:0007269	neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
2.1	6.4	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
2.1	17.0	GO:2000778	positive regulation of interleukin-6 secretion(GO:2000778)
2.1	27.6	GO:0060291	long-term synaptic potentiation(GO:0060291)
2.1	12.7	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
2.1	4.2	GO:0019673	GDP-mannose metabolic process(GO:0019673)
2.1	8.4	GO:0001757	somite specification(GO:0001757) collateral sprouting in absence of injury(GO:0048669)
2.1	6.3	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
2.1	56.5	GO:0046039	GTP metabolic process(GO:0046039)
2.1	6.3	GO:0019086	late viral transcription(GO:0019086)
2.1	10.4	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
2.1	12.4	GO:0007220	Notch receptor processing(GO:0007220)
2.1	12.4	GO:0010990	regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
2.1	20.6	GO:0002076	osteoblast development(GO:0002076)
2.1	39.0	GO:0046470	phosphatidylcholine metabolic process(GO:0046470)
2.0	2.0	GO:1904959	regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
2.0	2.0	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
2.0	4.1	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
2.0	16.3	GO:0001953	negative regulation of cell-matrix adhesion(GO:0001953)
2.0	4.1	GO:0043314	negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
2.0	4.1	GO:0014908	myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
2.0	4.1	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
2.0	4.0	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
2.0	8.1	GO:0071073	positive regulation of phospholipid biosynthetic process(GO:0071073)
2.0	88.3	GO:0065002	intracellular protein transmembrane transport(GO:0065002)
2.0	22.1	GO:0046697	decidualization(GO:0046697)
2.0	10.0	GO:2000774	positive regulation of cellular senescence(GO:2000774)
2.0	6.0	GO:0090204	protein localization to nuclear pore(GO:0090204)
2.0	11.9	GO:0048539	bone marrow development(GO:0048539)
2.0	31.8	GO:0006099	tricarboxylic acid cycle(GO:0006099)
2.0	15.8	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
2.0	27.7	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
2.0	84.9	GO:0051965	positive regulation of synapse assembly(GO:0051965)
2.0	5.9	GO:0033306	phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
2.0	15.7	GO:0048243	norepinephrine secretion(GO:0048243)
2.0	3.9	GO:0035963	cellular response to interleukin-13(GO:0035963)
2.0	9.8	GO:0006572	tyrosine catabolic process(GO:0006572)
2.0	7.8	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
1.9	42.9	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
1.9	7.8	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
1.9	48.6	GO:0034394	protein localization to cell surface(GO:0034394)
1.9	5.8	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
1.9	11.6	GO:2000209	regulation of anoikis(GO:2000209) positive regulation of anoikis(GO:2000210)
1.9	3.9	GO:0097069	cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
1.9	13.4	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
1.9	17.2	GO:0016540	protein autoprocessing(GO:0016540)
1.9	7.6	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
1.9	15.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
1.9	20.5	GO:0035337	fatty-acyl-CoA metabolic process(GO:0035337)
1.9	11.2	GO:0021796	cerebral cortex regionalization(GO:0021796)
1.9	7.4	GO:1990035	calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
1.9	24.1	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
1.9	11.1	GO:0060721	regulation of spongiotrophoblast cell proliferation(GO:0060721) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
1.9	16.7	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
1.8	3.7	GO:1903365	regulation of fear response(GO:1903365) regulation of behavioral fear response(GO:2000822)
1.8	12.9	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
1.8	22.0	GO:0032274	gonadotropin secretion(GO:0032274)
1.8	5.5	GO:0061042	vascular wound healing(GO:0061042)
1.8	23.8	GO:0045879	negative regulation of smoothened signaling pathway(GO:0045879)
1.8	5.5	GO:0051775	response to redox state(GO:0051775)
1.8	9.1	GO:0000160	phosphorelay signal transduction system(GO:0000160)
1.8	9.1	GO:0009414	response to water deprivation(GO:0009414)
1.8	1.8	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
1.8	41.5	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
1.8	1.8	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
1.8	12.6	GO:2000052	positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
1.8	5.4	GO:0014047	glutamate secretion(GO:0014047)
1.8	53.8	GO:0019935	cyclic-nucleotide-mediated signaling(GO:0019935)
1.8	17.9	GO:0035584	calcium-mediated signaling using intracellular calcium source(GO:0035584)
1.8	7.2	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
1.8	33.9	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
1.8	8.9	GO:0045901	positive regulation of translational elongation(GO:0045901)
1.8	8.9	GO:0032534	regulation of microvillus assembly(GO:0032534)
1.8	1.8	GO:0072053	renal inner medulla development(GO:0072053)
1.8	3.5	GO:0097120	receptor localization to synapse(GO:0097120)
1.8	8.8	GO:2000811	negative regulation of anoikis(GO:2000811)
1.7	3.5	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
1.7	19.1	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
1.7	19.1	GO:0042417	dopamine metabolic process(GO:0042417)
1.7	24.4	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.7	5.2	GO:0030252	growth hormone secretion(GO:0030252)
1.7	5.2	GO:0097298	regulation of nucleus size(GO:0097298)
1.7	29.4	GO:0010107	potassium ion import(GO:0010107)
1.7	6.9	GO:0060346	bone trabecula formation(GO:0060346)
1.7	3.4	GO:0060536	cartilage morphogenesis(GO:0060536)
1.7	36.0	GO:0018345	protein palmitoylation(GO:0018345)
1.7	15.4	GO:0060011	Sertoli cell proliferation(GO:0060011)
1.7	3.4	GO:0010847	regulation of chromatin assembly(GO:0010847)
1.7	1.7	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
1.7	1.7	GO:0010749	regulation of nitric oxide mediated signal transduction(GO:0010749)
1.7	10.2	GO:0032099	negative regulation of appetite(GO:0032099)
1.7	74.5	GO:1901379	regulation of potassium ion transmembrane transport(GO:1901379)
1.7	5.1	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
1.7	11.8	GO:1902592	viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
1.7	5.1	GO:0070257	positive regulation of mucus secretion(GO:0070257)
1.7	10.1	GO:0015074	DNA integration(GO:0015074)
1.7	11.8	GO:0000459	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
1.7	31.9	GO:2000649	regulation of sodium ion transmembrane transporter activity(GO:2000649)
1.7	5.0	GO:0090071	negative regulation of ribosome biogenesis(GO:0090071)
1.7	9.9	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
1.6	8.2	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
1.6	4.9	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
1.6	26.3	GO:0019236	response to pheromone(GO:0019236)
1.6	19.7	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
1.6	9.8	GO:0035330	regulation of hippo signaling(GO:0035330)
1.6	8.2	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
1.6	4.9	GO:0071691	cardiac muscle thin filament assembly(GO:0071691)
1.6	4.9	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
1.6	8.1	GO:0043116	negative regulation of vascular permeability(GO:0043116)
1.6	69.6	GO:0007219	Notch signaling pathway(GO:0007219)
1.6	9.7	GO:0060677	ureteric bud elongation(GO:0060677)
1.6	6.4	GO:1904707	positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
1.6	14.5	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
1.6	11.3	GO:0042048	olfactory behavior(GO:0042048)
1.6	4.8	GO:0016476	regulation of embryonic cell shape(GO:0016476)
1.6	1.6	GO:0002933	lipid hydroxylation(GO:0002933)
1.6	4.8	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
1.6	4.8	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
1.6	52.5	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
1.6	12.7	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
1.6	11.1	GO:0046457	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
1.6	4.7	GO:0008038	neuron recognition(GO:0008038)
1.6	15.7	GO:0006900	membrane budding(GO:0006900)
1.6	4.7	GO:0061303	cornea development in camera-type eye(GO:0061303)
1.6	1.6	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
1.6	1.6	GO:0098815	modulation of excitatory postsynaptic potential(GO:0098815)
1.6	14.0	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
1.5	7.7	GO:0045990	carbon catabolite regulation of transcription(GO:0045990)
1.5	13.9	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
1.5	7.7	GO:1903352	L-ornithine transmembrane transport(GO:1903352)
1.5	3.1	GO:0010459	negative regulation of heart rate(GO:0010459)
1.5	4.6	GO:1904181	positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
1.5	6.1	GO:0031179	peptide modification(GO:0031179)
1.5	4.6	GO:0048227	plasma membrane to endosome transport(GO:0048227)
1.5	9.1	GO:0035372	protein localization to microtubule(GO:0035372)
1.5	4.5	GO:0002477	antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
1.5	50.0	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
1.5	9.1	GO:0006693	prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
1.5	4.5	GO:0099612	protein localization to axon(GO:0099612)
1.5	3.0	GO:0009071	serine family amino acid catabolic process(GO:0009071)
1.5	6.0	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
1.5	14.9	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
1.5	32.8	GO:0016242	negative regulation of macroautophagy(GO:0016242)
1.5	6.0	GO:0002188	translation reinitiation(GO:0002188)
1.5	14.9	GO:1901984	negative regulation of protein acetylation(GO:1901984)
1.5	5.9	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
1.5	8.9	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.5	8.8	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
1.5	13.2	GO:0035994	response to muscle stretch(GO:0035994)
1.5	2.9	GO:0033133	positive regulation of glucokinase activity(GO:0033133)
1.5	5.8	GO:1904177	regulation of adipose tissue development(GO:1904177)
1.5	4.4	GO:0034163	regulation of toll-like receptor 9 signaling pathway(GO:0034163)
1.4	7.2	GO:0060068	vagina development(GO:0060068)
1.4	58.0	GO:0018208	protein peptidyl-prolyl isomerization(GO:0000413) peptidyl-proline modification(GO:0018208)
1.4	1.4	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
1.4	4.3	GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
1.4	2.9	GO:0021569	rhombomere 3 development(GO:0021569)
1.4	4.3	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
1.4	1.4	GO:0015811	L-cystine transport(GO:0015811)
1.4	4.3	GO:0070904	L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
1.4	10.0	GO:0007588	excretion(GO:0007588)
1.4	15.7	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
1.4	14.2	GO:2001224	positive regulation of neuron migration(GO:2001224)
1.4	2.8	GO:0030242	pexophagy(GO:0030242)
1.4	2.8	GO:0030186	melatonin metabolic process(GO:0030186)
1.4	9.8	GO:0046519	sphingoid metabolic process(GO:0046519)
1.4	7.0	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
1.4	4.2	GO:0021563	glossopharyngeal nerve development(GO:0021563)
1.4	4.2	GO:0019417	sulfur oxidation(GO:0019417)
1.4	11.1	GO:0046834	lipid phosphorylation(GO:0046834)
1.4	6.9	GO:0046621	negative regulation of organ growth(GO:0046621)
1.4	11.0	GO:0007000	nucleolus organization(GO:0007000)
1.4	5.5	GO:0061083	regulation of protein refolding(GO:0061083)
1.4	13.7	GO:0032933	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
1.4	5.5	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
1.4	6.8	GO:0008090	retrograde axonal transport(GO:0008090)
1.3	14.8	GO:0034498	early endosome to Golgi transport(GO:0034498)
1.3	1.3	GO:0009188	ribonucleoside diphosphate biosynthetic process(GO:0009188)
1.3	14.7	GO:0048753	melanosome organization(GO:0032438) pigment granule organization(GO:0048753)
1.3	10.6	GO:0042866	pyruvate biosynthetic process(GO:0042866)
1.3	2.7	GO:0071348	cellular response to interleukin-11(GO:0071348)
1.3	1.3	GO:0006701	progesterone biosynthetic process(GO:0006701)
1.3	2.6	GO:0032762	mast cell cytokine production(GO:0032762) regulation of mast cell cytokine production(GO:0032763)
1.3	14.6	GO:0007097	nuclear migration(GO:0007097)
1.3	11.9	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
1.3	2.6	GO:0006166	purine ribonucleoside salvage(GO:0006166)
1.3	10.5	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
1.3	15.7	GO:0000185	activation of MAPKKK activity(GO:0000185)
1.3	6.5	GO:0048251	elastic fiber assembly(GO:0048251)
1.3	3.9	GO:1903977	positive regulation of glial cell migration(GO:1903977)
1.3	9.1	GO:0001919	regulation of receptor recycling(GO:0001919)
1.3	3.9	GO:0035728	response to hepatocyte growth factor(GO:0035728)
1.3	3.9	GO:1900425	negative regulation of defense response to bacterium(GO:1900425)
1.3	9.0	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
1.3	2.5	GO:0051963	regulation of synapse assembly(GO:0051963)
1.3	6.4	GO:0060033	anatomical structure regression(GO:0060033)
1.3	11.3	GO:0035313	wound healing, spreading of epidermal cells(GO:0035313)
1.3	10.1	GO:0035418	protein localization to synapse(GO:0035418)
1.3	2.5	GO:0071387	cellular response to cortisol stimulus(GO:0071387)
1.3	3.8	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
1.2	21.2	GO:0031639	plasminogen activation(GO:0031639)
1.2	1.2	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
1.2	5.0	GO:0015838	amino-acid betaine transport(GO:0015838) carnitine transport(GO:0015879)
1.2	2.5	GO:2000821	regulation of grooming behavior(GO:2000821)
1.2	6.2	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
1.2	4.9	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
1.2	4.9	GO:2000035	regulation of stem cell division(GO:2000035)
1.2	2.5	GO:1903337	positive regulation of vacuolar transport(GO:1903337)
1.2	2.5	GO:0030321	transepithelial chloride transport(GO:0030321)
1.2	9.7	GO:2000505	regulation of energy homeostasis(GO:2000505)
1.2	20.6	GO:0061462	protein localization to lysosome(GO:0061462)
1.2	16.9	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
1.2	4.8	GO:0070141	response to UV-A(GO:0070141)
1.2	4.8	GO:1903779	regulation of cardiac conduction(GO:1903779)
1.2	10.7	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
1.2	9.4	GO:0000271	polysaccharide biosynthetic process(GO:0000271)
1.2	1.2	GO:0030214	hyaluronan catabolic process(GO:0030214)
1.2	31.8	GO:0045921	positive regulation of exocytosis(GO:0045921)
1.2	34.1	GO:0016126	sterol biosynthetic process(GO:0016126)
1.2	8.2	GO:0034389	lipid particle organization(GO:0034389)
1.2	7.0	GO:0002329	pre-B cell differentiation(GO:0002329)
1.2	4.6	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
1.2	6.9	GO:0021514	ventral spinal cord interneuron differentiation(GO:0021514)
1.2	4.6	GO:0006272	leading strand elongation(GO:0006272)
1.2	3.5	GO:0046349	amino sugar biosynthetic process(GO:0046349)
1.2	17.3	GO:0009062	fatty acid catabolic process(GO:0009062)
1.2	8.1	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
1.1	2.3	GO:0098759	response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
1.1	1.1	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
1.1	27.5	GO:0006911	phagocytosis, engulfment(GO:0006911)
1.1	9.1	GO:0002347	response to tumor cell(GO:0002347)
1.1	28.5	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
1.1	14.8	GO:0006509	membrane protein ectodomain proteolysis(GO:0006509)
1.1	3.4	GO:0008300	isoprenoid catabolic process(GO:0008300)
1.1	9.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
1.1	68.0	GO:0000187	activation of MAPK activity(GO:0000187)
1.1	7.9	GO:0010668	ectodermal cell differentiation(GO:0010668)
1.1	3.4	GO:0098507	polynucleotide 5' dephosphorylation(GO:0098507)
1.1	5.6	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
1.1	10.1	GO:0051764	actin crosslink formation(GO:0051764)
1.1	18.9	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
1.1	26.2	GO:0006730	one-carbon metabolic process(GO:0006730)
1.1	36.9	GO:0006505	GPI anchor metabolic process(GO:0006505)
1.1	6.5	GO:0043032	positive regulation of macrophage activation(GO:0043032)
1.1	2.1	GO:0002741	regulation of cytokine secretion involved in immune response(GO:0002739) positive regulation of cytokine secretion involved in immune response(GO:0002741)
1.1	7.4	GO:0045048	protein insertion into ER membrane(GO:0045048)
1.1	16.9	GO:0031103	axon regeneration(GO:0031103)
1.1	5.3	GO:0008295	spermidine biosynthetic process(GO:0008295)
1.1	8.4	GO:0030449	regulation of complement activation(GO:0030449)
1.1	2.1	GO:0044026	DNA hypermethylation(GO:0044026)
1.0	3.1	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
1.0	7.3	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
1.0	6.3	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
1.0	3.1	GO:0009751	response to salicylic acid(GO:0009751)
1.0	35.4	GO:0032024	positive regulation of insulin secretion(GO:0032024)
1.0	20.8	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
1.0	4.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
1.0	3.1	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
1.0	12.4	GO:0045671	negative regulation of osteoclast differentiation(GO:0045671)
1.0	3.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
1.0	49.7	GO:0007612	learning(GO:0007612)
1.0	9.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
1.0	2.0	GO:0006152	purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
1.0	24.0	GO:0035987	endodermal cell differentiation(GO:0035987)
1.0	86.0	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.0	6.0	GO:0019674	NAD metabolic process(GO:0019674)
1.0	11.0	GO:0051220	cytoplasmic sequestering of protein(GO:0051220)
1.0	5.0	GO:0046460	triglyceride biosynthetic process(GO:0019432) neutral lipid biosynthetic process(GO:0046460) acylglycerol biosynthetic process(GO:0046463)
1.0	5.9	GO:0042574	retinal metabolic process(GO:0042574)
1.0	2.9	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
1.0	16.5	GO:0030318	melanocyte differentiation(GO:0030318)
1.0	4.9	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
1.0	4.9	GO:0042256	mature ribosome assembly(GO:0042256)
1.0	6.8	GO:0002026	regulation of the force of heart contraction(GO:0002026)
1.0	4.8	GO:0009804	phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
1.0	1.0	GO:0048262	determination of dorsal/ventral asymmetry(GO:0048262)
1.0	2.9	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
1.0	2.9	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
1.0	5.8	GO:0019395	fatty acid oxidation(GO:0019395)
1.0	1.0	GO:0072313	metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
1.0	21.1	GO:0007040	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
1.0	2.9	GO:0097049	motor neuron apoptotic process(GO:0097049)
0.9	2.8	GO:0006983	ER overload response(GO:0006983)
0.9	5.7	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.9	5.6	GO:0070295	renal water absorption(GO:0070295)
0.9	13.0	GO:0008340	determination of adult lifespan(GO:0008340)
0.9	8.3	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.9	1.8	GO:0048014	Tie signaling pathway(GO:0048014)
0.9	9.2	GO:0017121	phospholipid scrambling(GO:0017121)
0.9	13.8	GO:0017004	cytochrome complex assembly(GO:0017004)
0.9	4.6	GO:0007021	tubulin complex assembly(GO:0007021)
0.9	0.9	GO:0010875	positive regulation of cholesterol efflux(GO:0010875)
0.9	1.8	GO:0009065	glutamine family amino acid catabolic process(GO:0009065)
0.9	19.8	GO:0003014	renal system process(GO:0003014)
0.9	13.5	GO:0097352	autophagosome maturation(GO:0097352)
0.9	6.3	GO:0046185	aldehyde catabolic process(GO:0046185)
0.9	18.7	GO:0003009	skeletal muscle contraction(GO:0003009)
0.9	2.7	GO:0009249	protein lipoylation(GO:0009249)
0.9	0.9	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.9	0.9	GO:0042473	outer ear morphogenesis(GO:0042473)
0.9	6.2	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.9	6.1	GO:0032964	collagen biosynthetic process(GO:0032964)
0.9	24.5	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.9	7.0	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.9	3.5	GO:0015889	cobalamin transport(GO:0015889)
0.9	7.8	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.9	0.9	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.9	1.7	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.9	4.3	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.9	2.6	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.9	3.4	GO:0043649	dicarboxylic acid catabolic process(GO:0043649)
0.9	1.7	GO:0006480	N-terminal protein amino acid methylation(GO:0006480)
0.9	52.8	GO:1902476	chloride transmembrane transport(GO:1902476)
0.8	10.2	GO:0044273	sulfur compound catabolic process(GO:0044273)
0.8	1.7	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.8	4.2	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.8	1.7	GO:0060965	negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.8	6.7	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.8	0.8	GO:0035376	sterol import(GO:0035376) cholesterol import(GO:0070508)
0.8	1.7	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.8	22.6	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.8	1.7	GO:1990830	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.8	11.7	GO:0045687	positive regulation of glial cell differentiation(GO:0045687)
0.8	2.5	GO:0010819	regulation of T cell chemotaxis(GO:0010819)
0.8	16.6	GO:0006739	NADP metabolic process(GO:0006739)
0.8	9.1	GO:0048368	lateral mesoderm development(GO:0048368)
0.8	3.3	GO:0038166	angiotensin-activated signaling pathway(GO:0038166)
0.8	2.4	GO:0015705	iodide transport(GO:0015705)
0.8	1.6	GO:0050655	dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.8	2.4	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.8	8.1	GO:0034113	heterotypic cell-cell adhesion(GO:0034113)
0.8	6.5	GO:0019430	removal of superoxide radicals(GO:0019430)
0.8	10.5	GO:0031167	rRNA methylation(GO:0031167)
0.8	2.4	GO:0001555	oocyte growth(GO:0001555)
0.8	18.4	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.8	3.2	GO:0008215	spermine metabolic process(GO:0008215)
0.8	5.5	GO:0051255	spindle midzone assembly(GO:0051255)
0.8	1.6	GO:0016332	establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.8	2.4	GO:0018916	nitrobenzene metabolic process(GO:0018916)
0.8	6.3	GO:0030517	negative regulation of axon extension(GO:0030517)
0.8	7.8	GO:0070327	thyroid hormone transport(GO:0070327)
0.8	1.6	GO:0010999	regulation of eIF2 alpha phosphorylation by heme(GO:0010999)
0.8	13.2	GO:0001522	pseudouridine synthesis(GO:0001522)
0.8	19.2	GO:0008589	regulation of smoothened signaling pathway(GO:0008589)
0.8	1.5	GO:0046365	monosaccharide catabolic process(GO:0046365)
0.7	1.5	GO:0009794	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.7	16.4	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.7	5.2	GO:0000711	meiotic DNA repair synthesis(GO:0000711)
0.7	17.8	GO:0006664	glycolipid metabolic process(GO:0006664)
0.7	5.2	GO:0014003	oligodendrocyte development(GO:0014003)
0.7	2.9	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.7	1.5	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.7	2.2	GO:1901224	positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.7	3.5	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.7	5.0	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.7	7.1	GO:0008053	mitochondrial fusion(GO:0008053)
0.7	1.4	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.7	2.8	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.7	2.1	GO:0006691	leukotriene metabolic process(GO:0006691)
0.7	0.7	GO:1903748	negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.7	4.8	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.7	2.7	GO:0061709	reticulophagy(GO:0061709)
0.7	3.4	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.7	4.0	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.7	2.7	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.7	4.7	GO:1901661	quinone metabolic process(GO:1901661)
0.7	2.6	GO:0021633	optic nerve structural organization(GO:0021633)
0.7	2.6	GO:1901552	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.6	3.2	GO:0043312	neutrophil degranulation(GO:0043312)
0.6	2.6	GO:0051414	response to cortisol(GO:0051414)
0.6	2.6	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.6	0.6	GO:0071579	regulation of zinc ion transport(GO:0071579)
0.6	3.8	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.6	15.3	GO:0005977	glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.6	1.3	GO:0006433	prolyl-tRNA aminoacylation(GO:0006433)
0.6	1.3	GO:0018343	protein farnesylation(GO:0018343)
0.6	5.7	GO:0010793	regulation of mRNA export from nucleus(GO:0010793)
0.6	5.7	GO:0048662	negative regulation of smooth muscle cell proliferation(GO:0048662)
0.6	2.5	GO:0021526	medial motor column neuron differentiation(GO:0021526)
0.6	13.7	GO:0021762	substantia nigra development(GO:0021762)
0.6	3.1	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.6	3.1	GO:0035635	entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.6	4.3	GO:0046116	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.6	47.9	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.6	4.8	GO:0045214	sarcomere organization(GO:0045214)
0.6	6.6	GO:0008333	endosome to lysosome transport(GO:0008333)
0.6	2.9	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.6	1.2	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.6	5.1	GO:2001014	regulation of skeletal muscle cell differentiation(GO:2001014)
0.6	1.7	GO:0071763	nuclear membrane organization(GO:0071763)
0.6	0.6	GO:0021930	cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.6	3.9	GO:0010761	fibroblast migration(GO:0010761)
0.6	2.8	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.5	2.2	GO:1904751	positive regulation of protein localization to nucleolus(GO:1904751)
0.5	0.5	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.5	3.3	GO:0008063	Toll signaling pathway(GO:0008063)
0.5	2.2	GO:0048252	lauric acid metabolic process(GO:0048252)
0.5	1.6	GO:0055075	potassium ion homeostasis(GO:0055075)
0.5	2.2	GO:0000154	rRNA modification(GO:0000154)
0.5	28.4	GO:0006906	vesicle fusion(GO:0006906)
0.5	7.0	GO:0050901	leukocyte tethering or rolling(GO:0050901)
0.5	2.6	GO:0070914	UV-damage excision repair(GO:0070914)
0.5	16.2	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.5	2.6	GO:0001887	selenium compound metabolic process(GO:0001887)
0.5	2.0	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.5	3.0	GO:0010566	regulation of ketone biosynthetic process(GO:0010566)
0.5	1.0	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.5	3.5	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.5	2.9	GO:0046836	glycolipid transport(GO:0046836)
0.5	3.3	GO:0042761	very long-chain fatty acid biosynthetic process(GO:0042761)
0.5	1.4	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.5	2.4	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.5	1.9	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.5	2.3	GO:0060509	Type I pneumocyte differentiation(GO:0060509)
0.5	1.4	GO:0007041	lysosomal transport(GO:0007041)
0.5	9.2	GO:0006182	cGMP biosynthetic process(GO:0006182)
0.5	2.8	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.5	3.6	GO:0043278	response to morphine(GO:0043278)
0.4	3.1	GO:0032026	response to magnesium ion(GO:0032026)
0.4	0.9	GO:0090131	mesenchyme migration(GO:0090131)
0.4	3.0	GO:0006068	ethanol catabolic process(GO:0006068) primary alcohol catabolic process(GO:0034310)
0.4	2.5	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
0.4	1.7	GO:0090201	negative regulation of release of cytochrome c from mitochondria(GO:0090201)
0.4	4.6	GO:0045761	regulation of adenylate cyclase activity(GO:0045761)
0.4	4.2	GO:0015747	urate transport(GO:0015747)
0.4	28.0	GO:0006457	protein folding(GO:0006457)
0.4	5.8	GO:0033108	mitochondrial respiratory chain complex assembly(GO:0033108)
0.4	5.0	GO:0009268	response to pH(GO:0009268)
0.4	1.2	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.4	3.2	GO:0044243	multicellular organism catabolic process(GO:0044243)
0.4	0.8	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.4	1.6	GO:0006868	glutamine transport(GO:0006868)
0.4	0.4	GO:0008216	spermidine metabolic process(GO:0008216)
0.4	1.1	GO:1902950	regulation of dendritic spine maintenance(GO:1902950)
0.4	0.7	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.4	3.7	GO:0006497	protein lipidation(GO:0006497)
0.4	1.4	GO:2000303	regulation of sphingolipid biosynthetic process(GO:0090153) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.3	2.1	GO:0046456	leukotriene biosynthetic process(GO:0019370) icosanoid biosynthetic process(GO:0046456) fatty acid derivative biosynthetic process(GO:1901570)
0.3	3.4	GO:0042743	hydrogen peroxide metabolic process(GO:0042743)
0.3	8.9	GO:0006637	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.3	0.3	GO:1900039	positive regulation of cellular response to hypoxia(GO:1900039)
0.3	1.0	GO:0009838	abscission(GO:0009838)
0.3	4.7	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.3	1.7	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.3	1.0	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.3	19.3	GO:1903955	positive regulation of protein targeting to mitochondrion(GO:1903955)
0.3	11.8	GO:0032543	mitochondrial translation(GO:0032543)
0.3	0.9	GO:1900016	negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.3	1.2	GO:0007512	adult heart development(GO:0007512)
0.3	2.5	GO:0006024	glycosaminoglycan biosynthetic process(GO:0006024)
0.3	0.9	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.3	1.8	GO:0000469	cleavage involved in rRNA processing(GO:0000469)
0.3	0.9	GO:0000963	mitochondrial RNA processing(GO:0000963) mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.3	4.2	GO:0006855	drug transmembrane transport(GO:0006855)
0.3	3.2	GO:0036065	fucosylation(GO:0036065)
0.3	1.2	GO:0010666	positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.3	2.0	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.3	1.7	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.3	1.1	GO:0098734	macromolecule depalmitoylation(GO:0098734)
0.3	1.0	GO:1900745	positive regulation of p38MAPK cascade(GO:1900745)
0.3	8.9	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.2	4.5	GO:1900181	negative regulation of protein localization to nucleus(GO:1900181)
0.2	1.7	GO:0032757	positive regulation of interleukin-8 production(GO:0032757)
0.2	8.2	GO:0010508	positive regulation of autophagy(GO:0010508)
0.2	1.4	GO:0097461	ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2	1.2	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.2	1.8	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.2	0.9	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.2	1.5	GO:0035094	response to nicotine(GO:0035094)
0.2	0.9	GO:0090042	tubulin deacetylation(GO:0090042)
0.2	2.1	GO:0046887	positive regulation of hormone secretion(GO:0046887)
0.2	4.3	GO:2000177	regulation of neural precursor cell proliferation(GO:2000177)
0.2	1.0	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.2	0.6	GO:0033032	regulation of myeloid cell apoptotic process(GO:0033032)
0.2	0.6	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
0.2	0.7	GO:2000404	regulation of T cell migration(GO:2000404)
0.2	0.5	GO:0044376	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.2	0.5	GO:0015825	L-serine transport(GO:0015825)
0.2	5.0	GO:0018149	peptide cross-linking(GO:0018149)
0.2	3.2	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.2	0.3	GO:0071603	endothelial cell-cell adhesion(GO:0071603)
0.2	0.5	GO:0044854	plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857)
0.2	0.5	GO:1990928	response to amino acid starvation(GO:1990928)
0.2	1.7	GO:0002227	innate immune response in mucosa(GO:0002227)
0.2	2.7	GO:0031572	mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.1	1.2	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.1	2.6	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1	1.2	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.1	0.9	GO:0006828	manganese ion transport(GO:0006828)
0.1	0.5	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.1	0.1	GO:0046104	thymidine metabolic process(GO:0046104)
0.1	0.1	GO:1900377	regulation of melanin biosynthetic process(GO:0048021) negative regulation of melanin biosynthetic process(GO:0048022) regulation of secondary metabolite biosynthetic process(GO:1900376) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1	0.3	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.1	4.0	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.1	1.3	GO:0006415	translational termination(GO:0006415)
0.1	0.2	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.1	0.8	GO:0061025	membrane fusion(GO:0061025)
0.0	0.3	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.3	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.0	0.0	GO:0090141	positive regulation of mitochondrial fission(GO:0090141)
0.0	0.1	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
21.2	63.5	GO:0044302	dentate gyrus mossy fiber(GO:0044302)
21.1	63.3	GO:0014801	longitudinal sarcoplasmic reticulum(GO:0014801) calcium ion-transporting ATPase complex(GO:0090534)
19.8	59.4	GO:0034667	integrin alpha3-beta1 complex(GO:0034667)
17.7	53.1	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
17.6	35.1	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
17.3	51.8	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
15.0	104.8	GO:0044300	cerebellar mossy fiber(GO:0044300)
14.2	85.3	GO:0033269	internode region of axon(GO:0033269)
14.0	139.6	GO:0048787	presynaptic active zone membrane(GO:0048787)
13.9	41.8	GO:0038039	G-protein coupled receptor heterodimeric complex(GO:0038039)
13.9	41.7	GO:1990257	piccolo-bassoon transport vesicle(GO:1990257)
13.7	13.7	GO:0060187	cell pole(GO:0060187)
13.1	65.4	GO:0044316	cone cell pedicle(GO:0044316)
13.1	52.2	GO:0043259	laminin-10 complex(GO:0043259)
13.0	52.0	GO:0044301	climbing fiber(GO:0044301)
13.0	38.9	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
12.3	49.3	GO:0097513	myosin II filament(GO:0097513)
11.8	35.5	GO:0098830	presynaptic endosome(GO:0098830)
11.8	59.1	GO:0035976	AP1 complex(GO:0035976)
11.5	23.1	GO:0036488	CHOP-C/EBP complex(GO:0036488)
11.3	56.5	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
11.3	33.8	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
11.1	33.3	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
10.8	32.4	GO:0045242	mitochondrial isocitrate dehydrogenase complex (NAD+)(GO:0005962) isocitrate dehydrogenase complex (NAD+)(GO:0045242)
10.5	52.6	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
10.3	165.5	GO:0031045	dense core granule(GO:0031045)
9.9	29.6	GO:0097444	spine apparatus(GO:0097444)
9.7	126.4	GO:0043083	synaptic cleft(GO:0043083)
9.2	110.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
9.1	45.5	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
8.9	17.8	GO:0042583	chromaffin granule(GO:0042583)
8.8	87.9	GO:0005883	neurofilament(GO:0005883)
8.8	26.4	GO:1990796	photoreceptor cell terminal bouton(GO:1990796)
8.8	26.3	GO:0098837	postsynaptic recycling endosome(GO:0098837)
8.6	43.1	GO:0005927	muscle tendon junction(GO:0005927)
8.6	34.3	GO:0044308	axonal spine(GO:0044308)
8.4	50.7	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
8.4	8.4	GO:0070820	tertiary granule(GO:0070820)
8.4	50.1	GO:0098839	postsynaptic density membrane(GO:0098839)
8.3	8.3	GO:1902710	GABA receptor complex(GO:1902710)
8.3	24.9	GO:0005945	6-phosphofructokinase complex(GO:0005945)
8.3	33.0	GO:0005588	collagen type V trimer(GO:0005588)
8.2	16.4	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
8.1	16.2	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
7.9	47.4	GO:0097470	ribbon synapse(GO:0097470)
7.8	38.9	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
7.7	115.9	GO:0032591	dendritic spine membrane(GO:0032591)
7.5	89.8	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
7.3	29.4	GO:0045298	tubulin complex(GO:0045298)
7.3	21.8	GO:0071148	TEAD-1-YAP complex(GO:0071148)
7.2	14.3	GO:0098888	extrinsic component of presynaptic membrane(GO:0098888)
7.1	42.9	GO:1990246	uniplex complex(GO:1990246)
7.0	49.3	GO:0000137	Golgi cis cisterna(GO:0000137)
6.9	315.2	GO:0048786	presynaptic active zone(GO:0048786)
6.5	19.6	GO:0045203	intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
6.5	52.2	GO:0005915	zonula adherens(GO:0005915)
6.5	149.8	GO:0032590	dendrite membrane(GO:0032590)
6.5	91.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
6.4	19.3	GO:0005592	collagen type XI trimer(GO:0005592)
6.4	76.9	GO:0016600	flotillin complex(GO:0016600)
6.4	44.8	GO:0032584	growth cone membrane(GO:0032584)
6.4	31.9	GO:0045335	phagocytic vesicle(GO:0045335)
6.4	12.7	GO:0033270	paranode region of axon(GO:0033270)
6.3	19.0	GO:0035253	ciliary rootlet(GO:0035253)
6.2	12.3	GO:0031088	platelet dense granule membrane(GO:0031088)
6.1	24.4	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
6.0	29.8	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
5.9	23.6	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
5.8	17.5	GO:1902560	GMP reductase complex(GO:1902560)
5.8	34.7	GO:0005955	calcineurin complex(GO:0005955)
5.7	62.5	GO:0071437	invadopodium(GO:0071437)
5.6	33.7	GO:0044327	dendritic spine head(GO:0044327)
5.4	21.4	GO:0042584	chromaffin granule membrane(GO:0042584)
5.3	15.8	GO:0005818	astral microtubule(GO:0000235) aster(GO:0005818)
5.2	67.7	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
5.1	35.9	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
5.1	20.5	GO:0005593	FACIT collagen trimer(GO:0005593)
5.1	40.6	GO:0097512	cardiac myofibril(GO:0097512)
5.1	15.2	GO:0005960	glycine cleavage complex(GO:0005960)
5.0	135.7	GO:0097440	apical dendrite(GO:0097440)
5.0	60.2	GO:0005796	Golgi lumen(GO:0005796)
5.0	15.1	GO:0070821	azurophil granule membrane(GO:0035577) tertiary granule membrane(GO:0070821)
5.0	14.9	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
5.0	138.8	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
4.9	19.8	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
4.9	103.9	GO:0043194	axon initial segment(GO:0043194)
4.9	14.6	GO:0099634	postsynaptic specialization membrane(GO:0099634)
4.8	38.7	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
4.8	57.1	GO:0031143	pseudopodium(GO:0031143)
4.7	118.5	GO:0032589	neuron projection membrane(GO:0032589)
4.7	28.0	GO:0030478	actin cap(GO:0030478)
4.6	32.3	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
4.6	41.0	GO:0030314	junctional membrane complex(GO:0030314)
4.5	40.5	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
4.5	8.9	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
4.4	444.6	GO:0043195	terminal bouton(GO:0043195)
4.4	22.2	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
4.4	22.1	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
4.4	17.7	GO:0044393	microspike(GO:0044393)
4.4	180.1	GO:0043034	costamere(GO:0043034)
4.3	17.3	GO:0035363	histone locus body(GO:0035363)
4.3	29.9	GO:0061617	MICOS complex(GO:0061617)
4.3	25.6	GO:0097443	sorting endosome(GO:0097443)
4.3	4.3	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
4.2	12.6	GO:0016935	glycine-gated chloride channel complex(GO:0016935) GABA-ergic synapse(GO:0098982)
4.2	70.7	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
4.1	66.2	GO:0043196	varicosity(GO:0043196)
4.1	12.4	GO:0097543	ciliary inversin compartment(GO:0097543)
4.1	12.4	GO:0002178	palmitoyltransferase complex(GO:0002178)
4.1	12.2	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
4.1	12.2	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
4.0	32.3	GO:0035749	myelin sheath adaxonal region(GO:0035749)
4.0	168.7	GO:0016529	sarcoplasmic reticulum(GO:0016529)
4.0	124.3	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
4.0	15.9	GO:0045273	respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281)
4.0	102.8	GO:0032588	trans-Golgi network membrane(GO:0032588)
3.9	7.9	GO:0031095	platelet dense tubular network membrane(GO:0031095)
3.9	11.7	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
3.8	740.7	GO:0043209	myelin sheath(GO:0043209)
3.8	34.3	GO:0097449	astrocyte projection(GO:0097449)
3.7	11.2	GO:0045098	type III intermediate filament(GO:0045098)
3.7	250.6	GO:0043679	axon terminus(GO:0043679)
3.7	97.0	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
3.7	52.1	GO:0060077	inhibitory synapse(GO:0060077)
3.7	36.9	GO:0042587	glycogen granule(GO:0042587)
3.6	21.9	GO:1990393	3M complex(GO:1990393)
3.6	86.8	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
3.6	39.8	GO:0031258	lamellipodium membrane(GO:0031258)
3.6	54.1	GO:0016460	myosin II complex(GO:0016460)
3.6	10.8	GO:0071942	XPC complex(GO:0071942)
3.5	94.0	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
3.5	58.8	GO:0042599	lamellar body(GO:0042599)
3.4	17.1	GO:1990696	USH2 complex(GO:1990696)
3.4	622.3	GO:0097060	synaptic membrane(GO:0097060)
3.4	34.0	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
3.4	23.7	GO:0044294	dendritic growth cone(GO:0044294)
3.4	64.0	GO:0034706	sodium channel complex(GO:0034706)
3.4	114.5	GO:0030315	T-tubule(GO:0030315)
3.4	53.8	GO:0045180	basal cortex(GO:0045180)
3.3	13.4	GO:0005827	polar microtubule(GO:0005827)
3.3	3.3	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
3.3	16.7	GO:0048179	activin receptor complex(GO:0048179)
3.2	9.5	GO:0036117	hyaluranon cable(GO:0036117)
3.1	18.7	GO:0098871	postsynaptic actin cytoskeleton(GO:0098871) postsynaptic cytoskeleton(GO:0099571)
3.1	15.5	GO:0000835	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
3.1	36.7	GO:0030008	TRAPP complex(GO:0030008)
3.0	17.9	GO:0032059	bleb(GO:0032059)
3.0	38.4	GO:0044754	autolysosome(GO:0044754)
2.9	28.7	GO:0030125	clathrin vesicle coat(GO:0030125)
2.9	17.2	GO:0005787	signal peptidase complex(GO:0005787)
2.9	14.3	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
2.8	22.5	GO:0000815	ESCRT III complex(GO:0000815)
2.8	8.3	GO:1990597	AIP1-IRE1 complex(GO:1990597)
2.7	8.2	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
2.7	8.2	GO:0045261	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
2.7	13.6	GO:0036449	microtubule minus-end(GO:0036449)
2.7	24.5	GO:0030877	beta-catenin destruction complex(GO:0030877)
2.7	8.1	GO:0008091	spectrin(GO:0008091)
2.7	13.5	GO:0043625	delta DNA polymerase complex(GO:0043625)
2.7	21.5	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
2.7	21.5	GO:0031428	box C/D snoRNP complex(GO:0031428)
2.7	13.4	GO:0098644	complex of collagen trimers(GO:0098644)
2.7	29.3	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
2.6	18.5	GO:0005869	dynactin complex(GO:0005869)
2.6	21.0	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
2.6	5.2	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306)
2.6	112.4	GO:0030864	cortical actin cytoskeleton(GO:0030864)
2.6	23.5	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
2.5	28.0	GO:0001891	phagocytic cup(GO:0001891)
2.5	32.9	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
2.5	17.6	GO:0033655	host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
2.5	7.5	GO:1990429	Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
2.5	79.5	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
2.5	14.8	GO:0005640	nuclear outer membrane(GO:0005640)
2.5	46.9	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
2.5	22.1	GO:0005861	troponin complex(GO:0005861)
2.5	7.4	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
2.4	4.9	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
2.4	7.3	GO:0001651	dense fibrillar component(GO:0001651)
2.4	70.2	GO:0055038	recycling endosome membrane(GO:0055038)
2.4	145.5	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
2.4	19.0	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
2.3	11.6	GO:0030015	CCR4-NOT core complex(GO:0030015)
2.3	4.6	GO:0031166	integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
2.3	6.8	GO:1990909	Wnt signalosome(GO:1990909)
2.3	11.3	GO:0044530	supraspliceosomal complex(GO:0044530)
2.2	211.4	GO:0005604	basement membrane(GO:0005604)
2.2	145.4	GO:0005811	lipid particle(GO:0005811)
2.2	11.2	GO:0016012	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
2.2	11.1	GO:0005797	Golgi medial cisterna(GO:0005797)
2.2	131.8	GO:0031902	late endosome membrane(GO:0031902)
2.2	28.4	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
2.1	12.9	GO:0032444	activin responsive factor complex(GO:0032444)
2.1	6.3	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
2.1	22.9	GO:0072546	ER membrane protein complex(GO:0072546)
2.1	14.5	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750)
2.1	12.4	GO:0031264	death-inducing signaling complex(GO:0031264)
2.0	53.3	GO:0034707	chloride channel complex(GO:0034707)
2.0	8.2	GO:0097196	Shu complex(GO:0097196)
2.0	22.1	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
2.0	12.0	GO:0000407	pre-autophagosomal structure(GO:0000407)
2.0	8.0	GO:0070552	BRISC complex(GO:0070552)
2.0	13.8	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
1.9	7.8	GO:0070545	PeBoW complex(GO:0070545)
1.9	24.3	GO:0060091	kinocilium(GO:0060091)
1.9	7.4	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
1.8	9.2	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
1.8	106.8	GO:0032580	Golgi cisterna membrane(GO:0032580)
1.8	7.3	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
1.8	25.4	GO:0030057	desmosome(GO:0030057)
1.8	63.6	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
1.8	67.0	GO:0030136	clathrin-coated vesicle(GO:0030136)
1.8	1.8	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
1.8	101.2	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
1.8	21.5	GO:0000421	autophagosome membrane(GO:0000421)
1.8	5.3	GO:0031527	filopodium membrane(GO:0031527)
1.8	17.6	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
1.8	144.5	GO:0005741	mitochondrial outer membrane(GO:0005741)
1.8	1.8	GO:0072588	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
1.7	8.7	GO:0071797	LUBAC complex(GO:0071797)
1.7	245.8	GO:0098793	presynapse(GO:0098793)
1.7	6.8	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.7	6.7	GO:0044291	cell-cell contact zone(GO:0044291)
1.7	20.1	GO:0031932	TORC2 complex(GO:0031932)
1.7	40.0	GO:0005921	gap junction(GO:0005921)
1.7	8.3	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
1.7	3.3	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
1.7	33.1	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
1.6	147.8	GO:0005770	late endosome(GO:0005770)
1.6	6.4	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
1.6	67.0	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
1.6	4.8	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
1.6	14.3	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
1.6	85.0	GO:0019898	extrinsic component of membrane(GO:0019898)
1.6	109.4	GO:0005913	cell-cell adherens junction(GO:0005913)
1.5	441.4	GO:0005759	mitochondrial matrix(GO:0005759)
1.5	12.1	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
1.5	52.8	GO:0042383	sarcolemma(GO:0042383)
1.5	96.2	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
1.4	13.0	GO:0032809	neuronal cell body membrane(GO:0032809)
1.4	4.3	GO:0033165	interphotoreceptor matrix(GO:0033165)
1.4	14.4	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
1.4	67.0	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
1.4	7.1	GO:0090661	box H/ACA telomerase RNP complex(GO:0090661)
1.4	4.2	GO:0016939	kinesin II complex(GO:0016939)
1.4	134.7	GO:0030427	site of polarized growth(GO:0030427)
1.4	6.9	GO:0070195	growth hormone receptor complex(GO:0070195)
1.4	18.0	GO:0000124	SAGA complex(GO:0000124)
1.4	13.8	GO:0034709	methylosome(GO:0034709)
1.4	47.9	GO:0005776	autophagosome(GO:0005776)
1.4	4.1	GO:1990826	nucleoplasmic periphery of the nuclear pore complex(GO:1990826)
1.4	2.7	GO:1990730	VCP-NSFL1C complex(GO:1990730)
1.4	16.2	GO:0005801	cis-Golgi network(GO:0005801)
1.3	113.3	GO:0043235	receptor complex(GO:0043235)
1.3	18.6	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
1.3	14.6	GO:0005905	clathrin-coated pit(GO:0005905)
1.3	84.8	GO:0042641	actomyosin(GO:0042641)
1.3	1.3	GO:0005899	insulin receptor complex(GO:0005899)
1.3	10.5	GO:0031985	Golgi cisterna(GO:0031985)
1.3	11.7	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
1.3	1.3	GO:0030690	Noc1p-Noc2p complex(GO:0030690)
1.3	5.1	GO:0005956	protein kinase CK2 complex(GO:0005956)
1.2	4.9	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
1.2	66.2	GO:0016323	basolateral plasma membrane(GO:0016323)
1.2	30.6	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
1.2	9.8	GO:0045259	proton-transporting ATP synthase complex(GO:0045259)
1.2	30.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
1.2	639.9	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
1.2	43.2	GO:0005581	collagen trimer(GO:0005581)
1.2	8.4	GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177)
1.2	89.1	GO:0030027	lamellipodium(GO:0030027)
1.2	7.1	GO:0008290	F-actin capping protein complex(GO:0008290)
1.1	4.6	GO:1990745	GARP complex(GO:0000938) EARP complex(GO:1990745)
1.1	1.1	GO:0098574	cytoplasmic side of lysosomal membrane(GO:0098574)
1.1	2.2	GO:0097413	Lewy body(GO:0097413)
1.1	84.6	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
1.1	3.3	GO:1990879	CST complex(GO:1990879)
1.1	6.6	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
1.1	7.6	GO:0070382	exocytic vesicle(GO:0070382)
1.1	55.9	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
1.1	6.4	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
1.1	3.2	GO:0000125	PCAF complex(GO:0000125)
1.1	6.4	GO:0016272	prefoldin complex(GO:0016272)
1.1	5.3	GO:0097361	CIA complex(GO:0097361)
1.0	9.4	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
1.0	4.2	GO:0032432	actin filament bundle(GO:0032432)
1.0	97.7	GO:0030016	myofibril(GO:0030016)
1.0	63.2	GO:0005802	trans-Golgi network(GO:0005802)
1.0	15.7	GO:0002102	podosome(GO:0002102)
1.0	16.6	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
1.0	3.9	GO:0045179	apical cortex(GO:0045179)
1.0	9.6	GO:0034464	BBSome(GO:0034464)
1.0	1.9	GO:0005683	U7 snRNP(GO:0005683)
0.9	251.9	GO:0043025	neuronal cell body(GO:0043025)
0.9	12.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.9	14.6	GO:0043198	dendritic shaft(GO:0043198)
0.9	87.0	GO:0030424	axon(GO:0030424)
0.9	6.3	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.9	6.2	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.9	2.6	GO:0033503	HULC complex(GO:0033503)
0.9	1.7	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.9	570.4	GO:0031226	intrinsic component of plasma membrane(GO:0031226)
0.8	5.1	GO:0005746	mitochondrial respiratory chain(GO:0005746)
0.8	2.5	GO:0032398	MHC class Ib protein complex(GO:0032398)
0.8	5.9	GO:0030870	Mre11 complex(GO:0030870)
0.8	14.0	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.8	2.4	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
0.8	1.6	GO:0070069	cytochrome complex(GO:0070069)
0.8	1.6	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.8	6.5	GO:0031082	BLOC complex(GO:0031082)
0.8	155.3	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.8	760.4	GO:0005739	mitochondrion(GO:0005739)
0.8	8.8	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.8	19.5	GO:0031526	brush border membrane(GO:0031526)
0.8	16.0	GO:0005682	U5 snRNP(GO:0005682)
0.8	12.1	GO:0000139	Golgi membrane(GO:0000139)
0.7	5.8	GO:0016589	NURF complex(GO:0016589)
0.7	13.7	GO:0031300	intrinsic component of organelle membrane(GO:0031300)
0.7	6.4	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.7	40.1	GO:0005769	early endosome(GO:0005769)
0.7	17.7	GO:0010008	endosome membrane(GO:0010008)
0.7	10.6	GO:0030133	transport vesicle(GO:0030133)
0.7	14.4	GO:0001533	cornified envelope(GO:0001533)
0.6	57.8	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.6	3.8	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.6	1.9	GO:0005687	U4 snRNP(GO:0005687)
0.6	6.0	GO:0001772	immunological synapse(GO:0001772)
0.6	73.3	GO:0031012	extracellular matrix(GO:0031012)
0.6	2.9	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.6	9.7	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.6	1.7	GO:0033263	CORVET complex(GO:0033263)
0.5	5.9	GO:0042629	mast cell granule(GO:0042629)
0.5	16.1	GO:0055037	recycling endosome(GO:0055037)
0.5	3.2	GO:0070847	core mediator complex(GO:0070847)
0.5	3.6	GO:0030991	intraciliary transport particle A(GO:0030991)
0.5	1.0	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.5	6.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.5	2.0	GO:0097524	sperm plasma membrane(GO:0097524)
0.5	1.4	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.5	11.1	GO:0016235	aggresome(GO:0016235)
0.5	0.9	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.5	1756.7	GO:0016021	integral component of membrane(GO:0016021)
0.4	2.1	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.4	1.7	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.4	3.7	GO:0036038	MKS complex(GO:0036038)
0.4	0.4	GO:0008537	proteasome activator complex(GO:0008537)
0.3	1.0	GO:0009328	phenylalanine-tRNA ligase complex(GO:0009328)
0.3	3.5	GO:0005686	U2 snRNP(GO:0005686)
0.3	1.1	GO:0042788	polysomal ribosome(GO:0042788)
0.3	0.6	GO:0097452	GAIT complex(GO:0097452)
0.3	9.5	GO:0005871	kinesin complex(GO:0005871)
0.3	38.5	GO:0005773	vacuole(GO:0005773)
0.2	0.9	GO:0032044	DSIF complex(GO:0032044)
0.2	0.6	GO:0032798	Swi5-Sfr1 complex(GO:0032798)
0.2	44.0	GO:0005783	endoplasmic reticulum(GO:0005783)
0.2	6.3	GO:0016592	mediator complex(GO:0016592)
0.2	0.5	GO:0005713	chiasma(GO:0005712) recombination nodule(GO:0005713)
0.2	0.8	GO:0042382	paraspeckles(GO:0042382)
0.1	1.3	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1	1.8	GO:0097546	ciliary base(GO:0097546)
0.1	0.3	GO:0031931	TORC1 complex(GO:0031931)
0.1	1.8	GO:0031225	anchored component of membrane(GO:0031225)
0.1	0.3	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.1	95.6	GO:0070062	extracellular exosome(GO:0070062)
0.1	1.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	2.4	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.5	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.3	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
28.1	84.3	GO:0016403	dimethylargininase activity(GO:0016403)
26.0	77.9	GO:0086057	voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
21.2	85.0	GO:0036004	GAF domain binding(GO:0036004)
19.1	57.2	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
18.9	94.3	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
18.8	93.8	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
16.0	48.1	GO:0035939	microsatellite binding(GO:0035939)
14.8	74.2	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
14.6	43.9	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
13.8	55.2	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
13.7	41.1	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
13.1	78.3	GO:0031749	D2 dopamine receptor binding(GO:0031749)
12.4	99.4	GO:1990430	extracellular matrix protein binding(GO:1990430)
12.4	37.1	GO:0051538	3 iron, 4 sulfur cluster binding(GO:0051538)
12.0	72.2	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
12.0	60.0	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
12.0	36.0	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
11.9	71.6	GO:0032051	clathrin light chain binding(GO:0032051)
11.7	35.2	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
11.5	34.6	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
11.5	34.6	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
11.5	45.8	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
11.4	34.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
11.3	79.2	GO:0097109	neuroligin family protein binding(GO:0097109)
10.8	32.3	GO:0004359	glutaminase activity(GO:0004359)
10.6	95.4	GO:0043208	glycosphingolipid binding(GO:0043208)
10.4	41.7	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
10.4	52.0	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
10.4	83.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
10.3	51.5	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
10.3	30.8	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
10.2	71.2	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
10.1	70.5	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
10.0	39.9	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
9.9	39.8	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
9.6	28.9	GO:0004618	phosphoglycerate kinase activity(GO:0004618)
9.4	37.4	GO:0099510	calcium ion binding involved in regulation of cytosolic calcium ion concentration(GO:0099510)
9.3	111.4	GO:0019911	structural constituent of myelin sheath(GO:0019911)
9.3	27.8	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
9.2	73.7	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
9.0	45.2	GO:0004614	phosphoglucomutase activity(GO:0004614)
8.9	97.6	GO:0019855	calcium channel inhibitor activity(GO:0019855)
8.9	35.5	GO:0099609	microtubule lateral binding(GO:0099609)
8.9	26.6	GO:0004736	pyruvate carboxylase activity(GO:0004736)
8.8	123.2	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
8.8	26.4	GO:0004020	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
8.8	43.8	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
8.7	26.2	GO:0008254	3'-nucleotidase activity(GO:0008254)
8.7	60.7	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
8.6	77.4	GO:0005347	ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
8.5	42.6	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
8.5	8.5	GO:0015141	succinate transmembrane transporter activity(GO:0015141)
8.5	33.9	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
8.4	50.7	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
8.3	66.1	GO:0005095	GTPase inhibitor activity(GO:0005095)
8.2	24.5	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
8.1	81.0	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
8.1	32.4	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
8.0	40.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
7.8	39.2	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
7.8	15.6	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
7.8	23.3	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
7.8	31.0	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
7.6	38.2	GO:0052834	inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
7.4	22.1	GO:0046911	metal chelating activity(GO:0046911)
7.3	29.3	GO:0086059	voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
7.3	36.4	GO:0008502	melatonin receptor activity(GO:0008502)
7.2	28.8	GO:0047751	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
7.1	28.6	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
7.1	21.4	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
7.1	28.4	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
7.0	28.1	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
7.0	27.9	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
6.8	20.5	GO:0008281	sulfonylurea receptor activity(GO:0008281)
6.8	6.8	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
6.8	13.5	GO:0004046	aminoacylase activity(GO:0004046)
6.8	20.3	GO:0047635	L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
6.6	19.8	GO:0004807	triose-phosphate isomerase activity(GO:0004807)
6.6	33.1	GO:0070052	collagen V binding(GO:0070052)
6.6	33.0	GO:0034186	apolipoprotein A-I binding(GO:0034186)
6.5	19.6	GO:0044736	acid-sensing ion channel activity(GO:0044736)
6.5	13.1	GO:0015292	uniporter activity(GO:0015292)
6.5	26.1	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
6.5	19.5	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
6.5	51.9	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
6.5	90.5	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
6.4	12.8	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
6.4	25.4	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
6.3	31.6	GO:0070404	NADH binding(GO:0070404)
6.3	138.4	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
6.2	43.6	GO:0043426	MRF binding(GO:0043426)
6.2	43.6	GO:0045503	dynein light chain binding(GO:0045503)
6.2	24.9	GO:0003872	6-phosphofructokinase activity(GO:0003872)
6.2	30.8	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
6.2	18.5	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
6.1	24.6	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
6.1	18.3	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
6.1	24.4	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
6.1	24.3	GO:0097108	hedgehog family protein binding(GO:0097108)
6.1	96.9	GO:0005351	sugar:proton symporter activity(GO:0005351)
6.0	151.1	GO:0031489	myosin V binding(GO:0031489)
6.0	24.0	GO:0031705	bombesin receptor binding(GO:0031705)
6.0	17.9	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
5.9	47.6	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
5.9	17.7	GO:2001070	starch binding(GO:2001070)
5.9	11.7	GO:0005290	L-histidine transmembrane transporter activity(GO:0005290)
5.9	35.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
5.9	17.6	GO:0034512	box C/D snoRNA binding(GO:0034512)
5.8	17.5	GO:0016657	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
5.8	17.3	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
5.7	63.2	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
5.7	46.0	GO:0071253	connexin binding(GO:0071253)
5.7	5.7	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
5.7	103.0	GO:0044548	S100 protein binding(GO:0044548)
5.7	17.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
5.7	28.5	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
5.7	17.1	GO:0033906	hyaluronoglucuronidase activity(GO:0033906)
5.7	22.7	GO:0004351	glutamate decarboxylase activity(GO:0004351)
5.7	17.0	GO:0043398	HLH domain binding(GO:0043398)
5.7	28.4	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
5.7	22.6	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733)
5.7	17.0	GO:0017113	dihydrouracil dehydrogenase (NAD+) activity(GO:0004159) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
5.6	22.6	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
5.6	11.2	GO:0070051	fibrinogen binding(GO:0070051)
5.6	61.7	GO:0004887	thyroid hormone receptor activity(GO:0004887)
5.6	33.6	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
5.5	16.6	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
5.5	16.4	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
5.5	60.1	GO:0031681	G-protein beta-subunit binding(GO:0031681)
5.4	65.2	GO:0045294	alpha-catenin binding(GO:0045294)
5.4	16.2	GO:0004096	catalase activity(GO:0004096)
5.4	21.6	GO:0034604	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
5.4	21.5	GO:0015137	citrate transmembrane transporter activity(GO:0015137)
5.4	177.5	GO:0043236	laminin binding(GO:0043236)
5.3	79.4	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
5.3	15.8	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
5.3	15.8	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
5.3	52.5	GO:0070016	armadillo repeat domain binding(GO:0070016)
5.2	20.9	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
5.2	20.7	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
5.1	76.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
5.1	30.4	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
5.1	15.2	GO:0004657	proline dehydrogenase activity(GO:0004657)
5.0	25.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
5.0	69.8	GO:0030898	actin-dependent ATPase activity(GO:0030898)
4.9	54.3	GO:0008131	primary amine oxidase activity(GO:0008131)
4.9	14.7	GO:0001847	opsonin receptor activity(GO:0001847)
4.9	14.7	GO:0015216	purine nucleotide transmembrane transporter activity(GO:0015216)
4.9	19.6	GO:0003987	acetate-CoA ligase activity(GO:0003987)
4.9	14.6	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
4.8	19.3	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
4.8	33.7	GO:0030346	protein phosphatase 2B binding(GO:0030346)
4.8	24.1	GO:0004985	opioid receptor activity(GO:0004985)
4.8	14.4	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
4.8	14.3	GO:0032810	sterol response element binding(GO:0032810)
4.8	90.6	GO:0015026	coreceptor activity(GO:0015026)
4.8	157.2	GO:0001540	beta-amyloid binding(GO:0001540)
4.7	80.5	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
4.7	18.9	GO:0033149	FFAT motif binding(GO:0033149)
4.7	23.6	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
4.7	9.4	GO:0038100	nodal binding(GO:0038100)
4.7	65.9	GO:0042813	Wnt-activated receptor activity(GO:0042813)
4.7	18.8	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
4.7	93.7	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
4.7	46.8	GO:0042577	lipid phosphatase activity(GO:0042577)
4.7	32.7	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
4.6	139.1	GO:0030506	ankyrin binding(GO:0030506)
4.6	9.2	GO:0000104	succinate dehydrogenase activity(GO:0000104)
4.6	22.9	GO:0005042	netrin receptor activity(GO:0005042)
4.6	31.9	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
4.5	31.8	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
4.5	9.0	GO:0004385	guanylate kinase activity(GO:0004385)
4.5	18.0	GO:0019784	NEDD8-specific protease activity(GO:0019784)
4.5	162.0	GO:0017080	sodium channel regulator activity(GO:0017080)
4.5	71.8	GO:0035497	cAMP response element binding(GO:0035497)
4.5	268.6	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
4.4	44.1	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
4.4	8.8	GO:0019992	diacylglycerol binding(GO:0019992)
4.4	48.2	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
4.4	17.5	GO:0000298	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
4.3	52.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
4.3	17.4	GO:0098821	BMP receptor activity(GO:0098821)
4.3	60.1	GO:0042043	neurexin family protein binding(GO:0042043)
4.3	12.9	GO:0071885	N-terminal protein N-methyltransferase activity(GO:0071885)
4.3	25.6	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
4.3	12.8	GO:0004370	glycerol kinase activity(GO:0004370)
4.3	12.8	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
4.3	34.0	GO:0034190	apolipoprotein receptor binding(GO:0034190)
4.2	12.7	GO:0045550	geranylgeranyl reductase activity(GO:0045550)
4.2	21.1	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
4.2	12.6	GO:0019798	procollagen-proline 3-dioxygenase activity(GO:0019797) procollagen-proline dioxygenase activity(GO:0019798)
4.2	58.4	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
4.2	12.5	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
4.2	16.7	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
4.1	66.2	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
4.1	16.4	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
4.1	36.9	GO:0031748	D1 dopamine receptor binding(GO:0031748)
4.1	28.6	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
4.1	8.1	GO:0031752	D5 dopamine receptor binding(GO:0031752)
4.1	16.2	GO:0035727	lysophosphatidic acid binding(GO:0035727)
4.0	24.3	GO:0043495	protein anchor(GO:0043495)
4.0	32.3	GO:0008517	folic acid transporter activity(GO:0008517)
4.0	12.1	GO:0051430	corticotropin-releasing hormone receptor 1 binding(GO:0051430)
4.0	8.0	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
4.0	40.0	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
4.0	16.0	GO:0015056	corticotrophin-releasing factor receptor activity(GO:0015056) corticotropin-releasing hormone receptor activity(GO:0043404)
4.0	12.0	GO:1902379	chemoattractant activity involved in axon guidance(GO:1902379)
4.0	143.2	GO:0016836	hydro-lyase activity(GO:0016836)
4.0	123.1	GO:0017075	syntaxin-1 binding(GO:0017075)
4.0	23.7	GO:0019870	potassium channel inhibitor activity(GO:0019870)
3.9	19.7	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
3.9	47.2	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
3.9	11.7	GO:0001641	group II metabotropic glutamate receptor activity(GO:0001641)
3.9	11.6	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
3.9	11.6	GO:0000253	3-keto sterol reductase activity(GO:0000253)
3.9	7.7	GO:0048030	disaccharide binding(GO:0048030)
3.8	15.3	GO:0004949	cannabinoid receptor activity(GO:0004949)
3.8	26.7	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
3.8	19.0	GO:0048039	ubiquinone binding(GO:0048039)
3.8	117.5	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
3.8	60.5	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
3.8	15.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
3.8	30.1	GO:0004565	beta-galactosidase activity(GO:0004565)
3.7	15.0	GO:0042806	fucose binding(GO:0042806)
3.7	14.9	GO:0071532	ankyrin repeat binding(GO:0071532)
3.7	3.7	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
3.7	29.8	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
3.7	70.3	GO:0015459	potassium channel regulator activity(GO:0015459)
3.7	29.6	GO:0004035	alkaline phosphatase activity(GO:0004035)
3.7	51.6	GO:0030955	potassium ion binding(GO:0030955)
3.7	29.3	GO:0016421	CoA carboxylase activity(GO:0016421)
3.6	10.9	GO:0008670	2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
3.6	14.5	GO:1904288	BAT3 complex binding(GO:1904288)
3.6	18.1	GO:0089720	caspase binding(GO:0089720)
3.6	25.3	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
3.6	93.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
3.6	32.2	GO:0036310	annealing helicase activity(GO:0036310)
3.6	7.1	GO:0043559	insulin binding(GO:0043559)
3.6	17.8	GO:0050501	hyaluronan synthase activity(GO:0050501)
3.5	7.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
3.5	10.6	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
3.5	10.5	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
3.5	21.0	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
3.5	20.9	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
3.5	10.5	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
3.5	34.8	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
3.4	3.4	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
3.4	20.6	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
3.4	10.3	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
3.4	34.2	GO:0008242	omega peptidase activity(GO:0008242)
3.4	13.6	GO:0008489	UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
3.4	13.4	GO:0030984	kininogen binding(GO:0030984)
3.4	43.6	GO:0017147	Wnt-protein binding(GO:0017147)
3.3	26.8	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
3.3	86.9	GO:0004890	GABA-A receptor activity(GO:0004890)
3.3	30.1	GO:0045499	chemorepellent activity(GO:0045499)
3.3	30.0	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
3.3	39.5	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
3.3	3.3	GO:0015142	tricarboxylic acid transmembrane transporter activity(GO:0015142)
3.3	46.0	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
3.3	13.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
3.3	75.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
3.3	39.2	GO:0070402	NADPH binding(GO:0070402)
3.3	9.8	GO:0048495	Roundabout binding(GO:0048495)
3.3	16.3	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
3.3	16.3	GO:0043199	sulfate binding(GO:0043199)
3.2	3.2	GO:0016885	ligase activity, forming carbon-carbon bonds(GO:0016885)
3.2	6.5	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
3.2	29.1	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
3.2	9.6	GO:0002114	interleukin-33 receptor activity(GO:0002114)
3.2	9.6	GO:0016263	glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
3.2	25.5	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
3.2	15.9	GO:0051373	FATZ binding(GO:0051373)
3.2	9.5	GO:0008511	sodium:potassium:chloride symporter activity(GO:0008511)
3.2	12.7	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
3.2	22.1	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
3.1	40.9	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
3.1	12.5	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
3.1	9.4	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
3.1	25.0	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
3.1	65.6	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
3.1	71.7	GO:0035254	glutamate receptor binding(GO:0035254)
3.1	24.7	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
3.1	12.4	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
3.1	61.7	GO:0043394	proteoglycan binding(GO:0043394)
3.1	18.5	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
3.1	9.2	GO:0003844	1,4-alpha-glucan branching enzyme activity(GO:0003844)
3.1	33.9	GO:0050897	cobalt ion binding(GO:0050897)
3.1	12.3	GO:0031014	troponin T binding(GO:0031014)
3.1	12.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
3.0	9.1	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
3.0	9.0	GO:0030551	cyclic nucleotide binding(GO:0030551)
3.0	21.0	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
3.0	21.0	GO:0004111	creatine kinase activity(GO:0004111)
3.0	9.0	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
3.0	9.0	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
3.0	11.8	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
2.9	8.8	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
2.9	17.6	GO:0015368	calcium:sodium antiporter activity(GO:0005432) calcium:cation antiporter activity(GO:0015368)
2.9	29.3	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
2.9	26.3	GO:0032050	clathrin heavy chain binding(GO:0032050)
2.9	5.8	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
2.9	23.2	GO:0015232	heme transporter activity(GO:0015232)
2.9	31.5	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
2.9	14.3	GO:0004668	protein-arginine deiminase activity(GO:0004668)
2.9	22.8	GO:0031995	insulin-like growth factor II binding(GO:0031995)
2.9	22.8	GO:0045295	gamma-catenin binding(GO:0045295)
2.9	8.6	GO:0030350	iron-responsive element binding(GO:0030350)
2.8	11.4	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
2.8	71.1	GO:0050840	extracellular matrix binding(GO:0050840)
2.8	11.4	GO:0015295	solute:proton symporter activity(GO:0015295)
2.8	28.3	GO:0048156	tau protein binding(GO:0048156)
2.8	8.4	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
2.8	14.0	GO:0004064	arylesterase activity(GO:0004064)
2.8	16.8	GO:0034235	GPI anchor binding(GO:0034235)
2.8	8.4	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
2.8	11.2	GO:0045159	myosin II binding(GO:0045159)
2.8	19.4	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
2.8	8.3	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
2.8	27.7	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
2.8	22.1	GO:1903136	cuprous ion binding(GO:1903136)
2.8	11.0	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
2.7	8.2	GO:0004478	methionine adenosyltransferase activity(GO:0004478)
2.7	11.0	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
2.7	41.1	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
2.7	11.0	GO:0005003	ephrin receptor activity(GO:0005003)
2.7	246.5	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
2.7	16.4	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
2.7	81.7	GO:0030507	spectrin binding(GO:0030507)
2.7	19.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
2.7	271.1	GO:0044325	ion channel binding(GO:0044325)
2.7	16.3	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
2.7	8.1	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
2.7	59.4	GO:0005212	structural constituent of eye lens(GO:0005212)
2.7	21.6	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
2.7	5.4	GO:0005163	nerve growth factor receptor binding(GO:0005163)
2.7	16.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
2.6	13.2	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
2.6	7.9	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
2.6	88.6	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
2.6	54.4	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
2.6	18.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
2.6	12.9	GO:0061676	importin-alpha family protein binding(GO:0061676)
2.6	95.5	GO:0048306	calcium-dependent protein binding(GO:0048306)
2.6	12.8	GO:0034185	apolipoprotein binding(GO:0034185)
2.6	10.2	GO:0003839	gamma-glutamylcyclotransferase activity(GO:0003839)
2.6	15.3	GO:0051920	peroxiredoxin activity(GO:0051920)
2.5	35.4	GO:0050661	NADP binding(GO:0050661)
2.5	7.6	GO:0042731	PH domain binding(GO:0042731)
2.5	7.5	GO:0005502	11-cis retinal binding(GO:0005502)
2.5	25.0	GO:0016929	SUMO-specific protease activity(GO:0016929)
2.5	12.5	GO:0008381	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
2.5	9.9	GO:0046923	ER retention sequence binding(GO:0046923)
2.5	14.9	GO:0008320	protein transmembrane transporter activity(GO:0008320)
2.5	205.2	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
2.5	56.8	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
2.5	9.9	GO:0045545	syndecan binding(GO:0045545)
2.5	29.4	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
2.4	121.5	GO:0005201	extracellular matrix structural constituent(GO:0005201)
2.4	43.7	GO:0004707	MAP kinase activity(GO:0004707)
2.4	9.7	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
2.4	16.9	GO:0030957	Tat protein binding(GO:0030957)
2.4	7.3	GO:0097603	temperature-gated ion channel activity(GO:0097603)
2.4	4.8	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
2.4	14.4	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
2.4	4.8	GO:0038181	bile acid receptor activity(GO:0038181)
2.4	14.4	GO:0001515	opioid peptide activity(GO:0001515)
2.4	23.9	GO:0102338	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
2.4	21.5	GO:0070097	delta-catenin binding(GO:0070097)
2.4	9.5	GO:0043008	ATP-dependent protein binding(GO:0043008)
2.4	42.5	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
2.4	61.3	GO:0070412	R-SMAD binding(GO:0070412)
2.4	35.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
2.3	14.1	GO:1990226	histone methyltransferase binding(GO:1990226)
2.3	82.1	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
2.3	2.3	GO:0031628	opioid receptor binding(GO:0031628)
2.3	11.7	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
2.3	30.4	GO:0031418	L-ascorbic acid binding(GO:0031418)
2.3	2.3	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
2.3	18.4	GO:0070569	uridylyltransferase activity(GO:0070569)
2.3	27.6	GO:0005246	calcium channel regulator activity(GO:0005246)
2.3	4.6	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
2.3	89.3	GO:0005518	collagen binding(GO:0005518)
2.3	139.7	GO:0005178	integrin binding(GO:0005178)
2.3	38.7	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
2.3	36.4	GO:0017134	fibroblast growth factor binding(GO:0017134)
2.3	11.4	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
2.3	4.5	GO:0031871	proteinase activated receptor binding(GO:0031871)
2.3	11.3	GO:0034056	estrogen response element binding(GO:0034056)
2.3	40.7	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
2.3	11.3	GO:0048185	activin binding(GO:0048185)
2.3	27.0	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
2.2	4.5	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
2.2	20.2	GO:0015266	protein channel activity(GO:0015266)
2.2	4.5	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
2.2	6.7	GO:0008476	protein-tyrosine sulfotransferase activity(GO:0008476)
2.2	15.7	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
2.2	13.4	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
2.2	15.4	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
2.2	8.8	GO:0004673	protein histidine kinase activity(GO:0004673)
2.2	13.0	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
2.2	43.1	GO:0030552	cAMP binding(GO:0030552)
2.1	36.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
2.1	51.3	GO:0043015	gamma-tubulin binding(GO:0043015)
2.1	34.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
2.1	34.0	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
2.1	31.9	GO:0005537	mannose binding(GO:0005537)
2.1	6.3	GO:0042609	CD4 receptor binding(GO:0042609)
2.1	12.5	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
2.1	10.4	GO:0004145	diamine N-acetyltransferase activity(GO:0004145)
2.0	20.4	GO:0010181	FMN binding(GO:0010181)
2.0	4.1	GO:0050659	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
2.0	22.2	GO:0030215	semaphorin receptor binding(GO:0030215)
2.0	10.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
2.0	22.1	GO:0030276	clathrin binding(GO:0030276)
2.0	6.0	GO:0015254	glycerol channel activity(GO:0015254)
2.0	4.0	GO:0015168	polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168)
2.0	19.9	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
2.0	3.9	GO:0002060	purine nucleobase binding(GO:0002060)
2.0	5.9	GO:0008396	oxysterol 7-alpha-hydroxylase activity(GO:0008396)
2.0	2.0	GO:0019956	chemokine binding(GO:0019956)
1.9	31.1	GO:0016854	racemase and epimerase activity(GO:0016854)
1.9	25.2	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
1.9	5.8	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
1.9	11.6	GO:0017070	U6 snRNA binding(GO:0017070)
1.9	1.9	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
1.9	27.0	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
1.9	32.7	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
1.9	5.7	GO:0034511	U3 snoRNA binding(GO:0034511)
1.9	5.7	GO:0046870	cadmium ion binding(GO:0046870)
1.9	22.7	GO:0048018	receptor agonist activity(GO:0048018)
1.9	3.8	GO:0016917	GABA receptor activity(GO:0016917)
1.9	7.5	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
1.9	5.6	GO:0016015	morphogen activity(GO:0016015)
1.9	50.3	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
1.9	9.3	GO:0036033	mediator complex binding(GO:0036033)
1.9	7.4	GO:0036132	13-prostaglandin reductase activity(GO:0036132)
1.9	9.3	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
1.9	5.6	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
1.8	22.1	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
1.8	5.5	GO:0032564	dATP binding(GO:0032564)
1.8	5.5	GO:0072590	N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
1.8	11.0	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
1.8	3.6	GO:0015925	galactosidase activity(GO:0015925)
1.8	20.0	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
1.8	1.8	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
1.8	39.6	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.8	10.8	GO:0047134	protein-disulfide reductase activity(GO:0047134)
1.8	19.7	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
1.8	25.1	GO:0004659	prenyltransferase activity(GO:0004659)
1.8	1.8	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
1.8	8.9	GO:0001155	TFIIIA-class transcription factor binding(GO:0001155)
1.8	10.7	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
1.8	10.6	GO:0015189	L-lysine transmembrane transporter activity(GO:0015189)
1.8	10.6	GO:0070492	oligosaccharide binding(GO:0070492)
1.8	17.7	GO:0070700	BMP receptor binding(GO:0070700)
1.8	144.9	GO:0030165	PDZ domain binding(GO:0030165)
1.8	3.5	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
1.8	12.3	GO:0015279	store-operated calcium channel activity(GO:0015279)
1.8	17.5	GO:0008046	axon guidance receptor activity(GO:0008046)
1.8	49.1	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
1.7	8.7	GO:0017166	vinculin binding(GO:0017166)
1.7	10.5	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
1.7	103.0	GO:0017048	Rho GTPase binding(GO:0017048)
1.7	7.0	GO:0005329	dopamine transmembrane transporter activity(GO:0005329) dopamine:sodium symporter activity(GO:0005330)
1.7	36.6	GO:0042288	MHC class I protein binding(GO:0042288)
1.7	27.9	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
1.7	13.9	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
1.7	5.2	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
1.7	6.9	GO:0004903	growth hormone receptor activity(GO:0004903)
1.7	6.9	GO:0033130	acetylcholine receptor binding(GO:0033130)
1.7	53.5	GO:0097110	scaffold protein binding(GO:0097110)
1.7	22.4	GO:0005522	profilin binding(GO:0005522)
1.7	25.8	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
1.7	10.3	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
1.7	5.1	GO:0034040	lipid-transporting ATPase activity(GO:0034040) sterol-transporting ATPase activity(GO:0034041)
1.7	118.8	GO:0005496	steroid binding(GO:0005496)
1.7	60.7	GO:0005080	protein kinase C binding(GO:0005080)
1.7	42.0	GO:0005184	neuropeptide hormone activity(GO:0005184)
1.7	10.1	GO:1990459	transferrin receptor binding(GO:1990459)
1.7	24.8	GO:0070403	NAD+ binding(GO:0070403)
1.7	18.2	GO:0042809	vitamin D receptor binding(GO:0042809)
1.6	3.3	GO:0031177	phosphopantetheine binding(GO:0031177)
1.6	8.2	GO:0004969	histamine receptor activity(GO:0004969)
1.6	9.7	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
1.6	4.9	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
1.6	17.8	GO:0051400	BH domain binding(GO:0051400)
1.6	11.3	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
1.6	4.8	GO:0046527	glucosyltransferase activity(GO:0046527)
1.6	9.7	GO:0043522	leucine zipper domain binding(GO:0043522)
1.6	6.4	GO:0050816	phosphothreonine binding(GO:0050816)
1.6	12.8	GO:0031419	cobalamin binding(GO:0031419)
1.6	8.0	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
1.6	55.8	GO:0005484	SNAP receptor activity(GO:0005484)
1.6	4.8	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
1.6	39.7	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.6	23.7	GO:0022848	acetylcholine receptor activity(GO:0015464) acetylcholine-gated cation channel activity(GO:0022848)
1.6	6.3	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
1.5	12.4	GO:0004143	diacylglycerol kinase activity(GO:0004143)
1.5	16.9	GO:0005243	gap junction channel activity(GO:0005243)
1.5	3.1	GO:0004708	MAP kinase kinase activity(GO:0004708)
1.5	3.0	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
1.5	3.0	GO:0070905	serine binding(GO:0070905)
1.5	4.5	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
1.5	13.5	GO:0031402	sodium ion binding(GO:0031402)
1.5	6.0	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
1.5	8.9	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
1.5	1.5	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
1.5	5.9	GO:0016415	octanoyltransferase activity(GO:0016415)
1.5	16.1	GO:0008373	sialyltransferase activity(GO:0008373)
1.5	2.9	GO:0016453	C-acetyltransferase activity(GO:0016453)
1.5	5.8	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
1.4	5.8	GO:0016433	rRNA (adenine) methyltransferase activity(GO:0016433)
1.4	7.2	GO:0001595	angiotensin receptor activity(GO:0001595)
1.4	2.9	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
1.4	19.9	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
1.4	18.4	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
1.4	1.4	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
1.4	20.7	GO:0031005	filamin binding(GO:0031005)
1.4	41.3	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
1.4	5.5	GO:0008422	beta-glucosidase activity(GO:0008422)
1.4	5.5	GO:0046790	virion binding(GO:0046790)
1.4	5.5	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
1.4	5.4	GO:0045134	uridine-diphosphatase activity(GO:0045134)
1.3	35.0	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
1.3	15.8	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
1.3	27.6	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
1.3	2.6	GO:0001727	lipid kinase activity(GO:0001727)
1.3	3.9	GO:0004775	succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
1.3	25.9	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
1.3	2.6	GO:0098603	selenol Se-methyltransferase activity(GO:0098603)
1.3	3.8	GO:0048038	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057) quinone binding(GO:0048038)
1.3	7.7	GO:0033691	sialic acid binding(GO:0033691)
1.3	3.8	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
1.3	7.6	GO:0017040	ceramidase activity(GO:0017040)
1.3	26.4	GO:0016881	acid-amino acid ligase activity(GO:0016881)
1.3	2.5	GO:0071791	chemokine (C-C motif) ligand 5 binding(GO:0071791)
1.2	8.7	GO:0050072	m7G(5')pppN diphosphatase activity(GO:0050072)
1.2	18.6	GO:0008307	structural constituent of muscle(GO:0008307)
1.2	2.5	GO:0051379	epinephrine binding(GO:0051379)
1.2	4.9	GO:0035374	chondroitin sulfate binding(GO:0035374)
1.2	11.1	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
1.2	2.4	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
1.2	9.7	GO:0048406	nerve growth factor binding(GO:0048406)
1.2	37.6	GO:0030544	Hsp70 protein binding(GO:0030544)
1.2	3.6	GO:0019534	toxin transporter activity(GO:0019534)
1.2	21.6	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
1.2	1.2	GO:0015248	sterol transporter activity(GO:0015248)
1.2	9.5	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
1.2	5.9	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
1.2	15.3	GO:0015643	toxic substance binding(GO:0015643)
1.2	5.9	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
1.2	4.7	GO:0017128	phospholipid scramblase activity(GO:0017128)
1.2	7.0	GO:0015238	drug transmembrane transporter activity(GO:0015238)
1.2	3.5	GO:0004630	phospholipase D activity(GO:0004630)
1.2	2.3	GO:0050780	dopamine receptor binding(GO:0050780)
1.1	5.7	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
1.1	2.3	GO:0016882	cyclo-ligase activity(GO:0016882)
1.1	30.5	GO:0017022	myosin binding(GO:0017022)
1.1	3.4	GO:0004651	polynucleotide 5'-phosphatase activity(GO:0004651)
1.1	6.8	GO:0070300	phosphatidic acid binding(GO:0070300)
1.1	4.5	GO:0035514	DNA demethylase activity(GO:0035514)
1.1	2.2	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
1.1	28.6	GO:0005507	copper ion binding(GO:0005507)
1.1	26.4	GO:0016866	intramolecular transferase activity(GO:0016866)
1.1	1.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.1	8.5	GO:0016783	sulfurtransferase activity(GO:0016783)
1.0	232.3	GO:0003924	GTPase activity(GO:0003924)
1.0	8.3	GO:0051959	dynein light intermediate chain binding(GO:0051959)
1.0	5.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
1.0	2.0	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
1.0	424.7	GO:0005509	calcium ion binding(GO:0005509)
1.0	2.0	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
1.0	10.1	GO:0003746	translation elongation factor activity(GO:0003746)
1.0	6.0	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.0	7.8	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
1.0	2.9	GO:0033142	progesterone receptor binding(GO:0033142)
1.0	1.9	GO:0035473	lipase binding(GO:0035473)
1.0	1.9	GO:0071209	U7 snRNA binding(GO:0071209)
1.0	35.3	GO:0005254	chloride channel activity(GO:0005254)
1.0	37.2	GO:0070330	aromatase activity(GO:0070330)
0.9	6.6	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.9	14.1	GO:0004806	triglyceride lipase activity(GO:0004806)
0.9	5.6	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.9	4.6	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.9	9.3	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.9	0.9	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.9	2.8	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.9	8.3	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.9	10.0	GO:0042169	SH2 domain binding(GO:0042169)
0.9	7.2	GO:0050693	LBD domain binding(GO:0050693)
0.9	6.3	GO:0030620	U2 snRNA binding(GO:0030620)
0.9	32.3	GO:0016782	transferase activity, transferring sulfur-containing groups(GO:0016782)
0.9	16.0	GO:0005158	insulin receptor binding(GO:0005158)
0.9	2.7	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.9	11.5	GO:0051287	NAD binding(GO:0051287)
0.9	4.4	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.9	15.8	GO:0019842	vitamin binding(GO:0019842)
0.9	16.5	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.9	13.0	GO:0004622	lysophospholipase activity(GO:0004622)
0.9	1.7	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.9	9.5	GO:0008061	chitin binding(GO:0008061)
0.9	2.6	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.9	23.9	GO:0016790	thiolester hydrolase activity(GO:0016790)
0.9	1.7	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.8	14.3	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.8	25.0	GO:0008009	chemokine activity(GO:0008009)
0.8	66.2	GO:0051015	actin filament binding(GO:0051015)
0.8	2.5	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.8	5.6	GO:0019215	intermediate filament binding(GO:0019215)
0.8	4.7	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
0.8	5.4	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.8	107.1	GO:0003779	actin binding(GO:0003779)
0.8	2.3	GO:0019959	interleukin-8 receptor activity(GO:0004918) interleukin-8 binding(GO:0019959)
0.8	4.6	GO:0001972	retinoic acid binding(GO:0001972)
0.8	11.4	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.8	6.8	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.8	12.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.8	15.9	GO:0008483	transaminase activity(GO:0008483)
0.8	14.3	GO:0042805	actinin binding(GO:0042805)
0.8	27.9	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.8	6.0	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.7	6.0	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.7	3.0	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.7	47.1	GO:0016820	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.7	2.9	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.7	2.2	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.7	3.6	GO:0043014	alpha-tubulin binding(GO:0043014)
0.7	2.2	GO:0070883	pre-miRNA binding(GO:0070883)
0.7	3.6	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.7	2.2	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.7	14.4	GO:0004190	aspartic-type endopeptidase activity(GO:0004190)
0.7	7.8	GO:0016805	dipeptidase activity(GO:0016805)
0.7	117.6	GO:0005096	GTPase activator activity(GO:0005096)
0.7	21.2	GO:0005044	scavenger receptor activity(GO:0005044)
0.7	1.4	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.7	3.5	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.7	0.7	GO:0031893	vasopressin receptor binding(GO:0031893)
0.7	5.6	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.7	2.1	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.7	13.7	GO:0008171	O-methyltransferase activity(GO:0008171)
0.7	60.1	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.7	3.4	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.7	2.7	GO:1901612	phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.7	2.0	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.7	9.3	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.7	6.7	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.6	2.6	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.6	13.5	GO:0050699	WW domain binding(GO:0050699)
0.6	7.0	GO:0072341	modified amino acid binding(GO:0072341)
0.6	1.3	GO:0004827	proline-tRNA ligase activity(GO:0004827)
0.6	2.5	GO:0004977	melanocortin receptor activity(GO:0004977)
0.6	3.1	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.6	4.3	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.6	1.8	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.6	2.4	GO:0050733	RS domain binding(GO:0050733)
0.6	4.2	GO:0016594	glycine binding(GO:0016594)
0.6	2.9	GO:0031386	protein tag(GO:0031386)
0.6	29.6	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.6	13.8	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.6	1.7	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.6	1.1	GO:0052743	inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.6	3.4	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.6	2.2	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.6	4.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.5	4.4	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.5	1.6	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.5	8.7	GO:0004383	guanylate cyclase activity(GO:0004383)
0.5	2.7	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.5	3.8	GO:0050811	GABA receptor binding(GO:0050811)
0.5	4.3	GO:0005521	lamin binding(GO:0005521)
0.5	2.6	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.5	6.5	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.5	2.5	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.5	2.5	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467) very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.5	1.9	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.5	2.9	GO:0008428	ribonuclease inhibitor activity(GO:0008428)
0.5	1.4	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.4	0.9	GO:0032190	acrosin binding(GO:0032190)
0.4	3.5	GO:0016247	channel regulator activity(GO:0016247)
0.4	3.5	GO:0001671	ATPase activator activity(GO:0001671)
0.4	4.4	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.4	4.3	GO:0043176	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.4	1.3	GO:0004609	phosphatidylserine decarboxylase activity(GO:0004609)
0.4	3.4	GO:0016878	acid-thiol ligase activity(GO:0016878)
0.4	2.1	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.4	2.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.4	8.3	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.4	1.6	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.4	2.1	GO:0050700	CARD domain binding(GO:0050700)
0.4	4.5	GO:0035198	miRNA binding(GO:0035198)
0.4	5.7	GO:0017091	AU-rich element binding(GO:0017091)
0.4	2.0	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.4	2.0	GO:0047493	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.4	7.1	GO:0019905	syntaxin binding(GO:0019905)
0.4	3.9	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.4	4.7	GO:0048487	beta-tubulin binding(GO:0048487)
0.4	5.8	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.4	34.0	GO:0005525	GTP binding(GO:0005525)
0.4	2.2	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.4	2.9	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.4	8.6	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.3	4.9	GO:0008198	ferrous iron binding(GO:0008198)
0.3	4.1	GO:0051010	microtubule plus-end binding(GO:0051010)
0.3	16.0	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.3	8.0	GO:0016875	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.3	19.9	GO:0051082	unfolded protein binding(GO:0051082)
0.3	19.8	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.3	23.5	GO:0008514	organic anion transmembrane transporter activity(GO:0008514)
0.3	1.8	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.3	0.6	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.3	36.2	GO:0008237	metallopeptidase activity(GO:0008237)
0.3	1.4	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3	1.1	GO:0001156	TFIIIC-class transcription factor binding(GO:0001156)
0.3	3.1	GO:0071889	14-3-3 protein binding(GO:0071889)
0.3	5.2	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.2	1.0	GO:1990932	5.8S rRNA binding(GO:1990932)
0.2	3.6	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.2	40.1	GO:0050839	cell adhesion molecule binding(GO:0050839)
0.2	0.4	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.2	2.6	GO:0003951	NAD+ kinase activity(GO:0003951)
0.2	3.5	GO:0004721	phosphoprotein phosphatase activity(GO:0004721)
0.2	3.7	GO:0004407	histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.2	3.6	GO:0070566	adenylyltransferase activity(GO:0070566)
0.2	1.3	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2	0.9	GO:0005047	signal recognition particle binding(GO:0005047)
0.2	3.6	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.2	0.7	GO:0004594	pantothenate kinase activity(GO:0004594)
0.2	0.5	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	0.9	GO:0005536	glucose binding(GO:0005536)
0.1	1.0	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.1	1.5	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.1	0.6	GO:0061133	endopeptidase activator activity(GO:0061133)
0.1	1.9	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	0.7	GO:0004935	adrenergic receptor activity(GO:0004935)
0.1	0.5	GO:0047619	acylcarnitine hydrolase activity(GO:0047619)
0.1	0.5	GO:0070513	death domain binding(GO:0070513)
0.1	2.9	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	6.2	GO:0004896	cytokine receptor activity(GO:0004896)
0.1	0.8	GO:0004601	peroxidase activity(GO:0004601) oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
0.1	0.5	GO:0052745	inositol phosphate phosphatase activity(GO:0052745)
0.1	0.2	GO:0019863	IgE binding(GO:0019863)
0.1	0.5	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1	0.7	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	0.2	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.1	GO:0042562	hormone binding(GO:0042562)
0.0	36.1	GO:0004930	G-protein coupled receptor activity(GO:0004930)
0.0	0.1	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.2	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
13.5	13.5	PID GLYPICAN 1PATHWAY	Glypican 1 network
13.2	145.0	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
13.2	13.2	ST JAK STAT PATHWAY	Jak-STAT Pathway
12.2	12.2	PID IFNG PATHWAY	IFN-gamma pathway
6.5	194.2	PID S1P S1P2 PATHWAY	S1P2 pathway
6.4	82.6	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
6.0	113.5	PID LPA4 PATHWAY	LPA4-mediated signaling events
5.7	11.3	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
5.4	27.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
5.2	222.2	PID NCADHERIN PATHWAY	N-cadherin signaling events
5.1	122.9	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
4.8	161.8	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
4.6	59.8	PID S1P S1P3 PATHWAY	S1P3 pathway
4.6	77.6	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
4.4	30.6	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
4.3	108.4	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
4.0	23.7	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
3.8	30.4	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
3.7	88.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
3.6	126.9	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
3.6	64.5	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
3.6	25.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
3.5	56.6	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
3.5	17.5	ST JNK MAPK PATHWAY	JNK MAPK Pathway
3.5	121.1	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
3.4	109.3	PID RAS PATHWAY	Regulation of Ras family activation
3.4	44.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
3.3	61.9	PID ARF 3PATHWAY	Arf1 pathway
3.2	67.9	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
3.2	45.0	ST G ALPHA S PATHWAY	G alpha s Pathway
3.1	64.7	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
3.0	30.3	ST STAT3 PATHWAY	STAT3 Pathway
3.0	21.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
3.0	57.0	PID EPHB FWD PATHWAY	EPHB forward signaling
3.0	74.5	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
3.0	145.9	PID BMP PATHWAY	BMP receptor signaling
3.0	153.5	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
2.9	11.6	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
2.9	11.5	PID VEGFR1 PATHWAY	VEGFR1 specific signals
2.8	135.5	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
2.8	2.8	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
2.7	48.3	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
2.6	54.5	PID ENDOTHELIN PATHWAY	Endothelins
2.6	49.2	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
2.5	22.3	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
2.5	12.3	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
2.4	21.7	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
2.4	49.7	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
2.3	15.9	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
2.3	22.7	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
2.2	26.1	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
2.1	60.0	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
2.1	51.1	PID EPHA FWDPATHWAY	EPHA forward signaling
2.1	19.1	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
2.1	40.2	PID REELIN PATHWAY	Reelin signaling pathway
2.0	4.0	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
2.0	293.5	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
2.0	327.1	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
1.9	73.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
1.9	46.4	PID SHP2 PATHWAY	SHP2 signaling
1.8	12.6	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
1.7	11.7	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
1.6	8.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
1.6	46.9	PID RHOA PATHWAY	RhoA signaling pathway
1.6	43.6	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
1.6	360.3	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
1.6	74.9	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
1.6	38.8	NABA COLLAGENS	Genes encoding collagen proteins
1.5	35.4	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
1.5	61.0	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
1.4	2.8	ST GA12 PATHWAY	G alpha 12 Pathway
1.3	41.7	PID CERAMIDE PATHWAY	Ceramide signaling pathway
1.3	12.8	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
1.3	22.9	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
1.2	3.6	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
1.2	16.5	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
1.1	20.7	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
1.1	21.8	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
1.1	22.5	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
1.1	13.4	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
1.1	21.1	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
1.1	10.9	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
1.1	15.0	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
1.0	16.7	PID IL1 PATHWAY	IL1-mediated signaling events
1.0	3.8	PID FAS PATHWAY	FAS (CD95) signaling pathway
1.0	4.8	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.9	38.6	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.9	11.0	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.9	5.5	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.9	9.1	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.9	9.0	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.9	31.2	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.9	7.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.8	21.0	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.8	4.1	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.8	11.9	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.8	23.3	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.8	1.5	PID S1P S1P1 PATHWAY	S1P1 pathway
0.8	3.8	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.7	28.0	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.7	12.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.7	9.1	PID FOXO PATHWAY	FoxO family signaling
0.6	4.4	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.6	8.6	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.6	20.4	PID LKB1 PATHWAY	LKB1 signaling events
0.6	7.4	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.6	25.1	PID NOTCH PATHWAY	Notch signaling pathway
0.5	4.7	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.5	1.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.5	49.4	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.5	1.4	PID TRAIL PATHWAY	TRAIL signaling pathway
0.5	21.0	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.4	1.8	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.4	4.9	PID AP1 PATHWAY	AP-1 transcription factor network
0.4	2.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.4	9.5	PID ILK PATHWAY	Integrin-linked kinase signaling
0.4	3.3	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.4	2.8	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.3	16.9	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.3	3.5	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.2	2.9	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.2	46.4	NABA MATRISOME	Ensemble of genes encoding extracellular matrix and extracellular matrix-associated proteins
0.2	4.9	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.2	4.2	PID TNF PATHWAY	TNF receptor signaling pathway
0.2	4.8	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.2	0.9	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.1	2.8	PID FGF PATHWAY	FGF signaling pathway
0.1	4.5	PID P73PATHWAY	p73 transcription factor network
0.1	2.2	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	1.2	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.1	1.0	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.5	PID TGFBR PATHWAY	TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
18.1	36.2	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
13.9	208.2	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
12.5	149.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
12.0	24.0	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
9.1	81.5	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
9.0	153.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
8.8	131.4	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
8.5	102.1	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
7.9	63.1	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
7.7	85.0	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
7.7	7.7	REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
7.6	205.4	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
7.4	111.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
7.0	118.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
6.9	117.8	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
6.7	107.8	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
6.7	94.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
6.6	39.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
6.5	248.4	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
6.1	79.3	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
5.8	104.9	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
5.7	245.2	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
5.6	107.0	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
5.5	88.1	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
5.4	64.8	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
5.2	98.9	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
5.1	30.9	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
4.8	62.6	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
4.8	14.3	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
4.6	83.0	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
4.5	112.6	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
4.5	135.1	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
4.5	125.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
4.5	174.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
4.3	72.5	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
4.2	46.3	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
4.0	56.6	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
4.0	107.7	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
3.8	50.0	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
3.8	42.0	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
3.8	186.1	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
3.8	113.6	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
3.7	7.5	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
3.7	156.7	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
3.7	55.9	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
3.7	7.4	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
3.7	106.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
3.7	95.0	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
3.6	21.7	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
3.6	46.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
3.5	31.6	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
3.5	45.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
3.4	54.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
3.3	46.8	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
3.3	56.6	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
3.2	25.6	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
3.1	78.2	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
3.0	137.2	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
3.0	51.5	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
3.0	42.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
3.0	6.0	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
3.0	47.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
2.9	35.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
2.9	40.9	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
2.9	31.8	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
2.9	46.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
2.9	17.3	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
2.9	28.8	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
2.8	58.9	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
2.8	44.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
2.8	49.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
2.7	112.5	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
2.7	35.4	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
2.7	2.7	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
2.6	18.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
2.6	44.0	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
2.6	51.1	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
2.6	7.7	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
2.5	12.7	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
2.5	22.8	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
2.5	17.5	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
2.3	37.4	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
2.3	16.3	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
2.3	46.4	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
2.3	47.7	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
2.3	90.7	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
2.3	146.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
2.2	20.2	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
2.2	20.2	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
2.2	52.9	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
2.2	17.4	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
2.2	2.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
2.2	102.0	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
2.1	42.1	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
2.1	14.5	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
2.0	98.2	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
2.0	56.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
1.9	5.8	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
1.9	56.9	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
1.9	32.0	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
1.9	43.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
1.9	56.4	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
1.9	3.7	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
1.8	31.1	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
1.8	111.0	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
1.8	25.1	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
1.8	8.8	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
1.8	10.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
1.7	29.5	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
1.7	29.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
1.7	3.4	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
1.7	55.3	REACTOME SIGNALING BY NOTCH1	Genes involved in Signaling by NOTCH1
1.7	8.3	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
1.5	10.8	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
1.5	108.1	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
1.5	21.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
1.5	7.4	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
1.5	14.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
1.5	8.8	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
1.4	23.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
1.4	26.0	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
1.4	17.3	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
1.4	8.5	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
1.4	16.9	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
1.4	17.8	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
1.3	50.6	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
1.3	29.2	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
1.3	15.9	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
1.3	22.5	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
1.3	49.4	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
1.3	22.0	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
1.3	16.6	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
1.3	26.9	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
1.3	20.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
1.3	12.7	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
1.3	86.4	REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS	Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
1.2	22.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
1.2	18.5	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
1.2	9.8	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
1.2	19.0	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
1.2	7.1	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
1.2	18.8	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
1.2	104.9	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
1.1	7.8	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
1.1	40.0	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
1.1	5.5	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
1.1	2.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
1.0	132.7	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
1.0	25.7	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
1.0	10.8	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.9	9.3	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.9	11.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.9	12.8	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.9	17.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.9	3.6	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.9	9.6	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.9	7.8	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.9	89.3	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.9	36.3	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.9	27.3	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.8	3.4	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.8	45.2	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.7	11.8	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.7	5.8	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.7	19.0	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
0.7	11.9	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.7	29.9	REACTOME UNFOLDED PROTEIN RESPONSE	Genes involved in Unfolded Protein Response
0.7	66.9	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.6	14.0	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.6	6.7	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.6	3.6	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.6	4.0	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.5	1.6	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.5	4.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.5	2.6	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.5	8.0	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.5	27.8	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.5	11.3	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.5	2.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.5	1.8	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.4	14.8	REACTOME PI METABOLISM	Genes involved in PI Metabolism
0.4	13.2	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.4	6.1	REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	Genes involved in Transmission across Chemical Synapses
0.4	4.4	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.4	7.0	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.4	8.8	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.3	8.9	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.3	36.1	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.3	4.1	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.3	12.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.3	6.4	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.3	2.6	REACTOME SIGNALING BY ERBB4	Genes involved in Signaling by ERBB4
0.2	0.5	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.2	3.7	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.2	2.7	REACTOME SIGNALLING BY NGF	Genes involved in Signalling by NGF
0.2	2.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.2	1.6	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.2	0.9	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.2	4.2	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	1.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	0.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	1.0	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	0.8	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.1	2.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	5.1	REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM	Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.1	1.1	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.5	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.4	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.1	REACTOME PURINE METABOLISM	Genes involved in Purine metabolism

Results for Sp1

Z-value: 2.01

Motif logo

Transcription factors associated with Sp1

Activity-expression correlation:

Activity profile of Sp1 motif

Sorted Z-values of Sp1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sp1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: