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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Sox4

Z-value: 0.56

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Transcription factors associated with Sox4

Gene Symbol Gene ID Gene Info

Activity profile of Sox4 motif

Sorted Z-values of Sox4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_139528162 14.78 ENSRNOT00000014317
Slc7a11
solute carrier family 7 member 11
chr18_+_79406381 13.91 ENSRNOT00000022303
ENSRNOT00000058295
ENSRNOT00000058296
ENSRNOT00000022280
Mbp
myelin basic protein
chr9_-_100253609 13.12 ENSRNOT00000036061
Kif1a
kinesin family member 1A
chr8_+_128824508 13.11 ENSRNOT00000025343
Mobp
myelin-associated oligodendrocyte basic protein
chr1_+_234363994 13.04 ENSRNOT00000018137
Rorb
RAR-related orphan receptor B
chr9_+_117044533 12.52 ENSRNOT00000072916
Tmem200c
transmembrane protein 200C
chr3_-_91217491 11.87 ENSRNOT00000006115
Rag1
recombination activating 1
chrX_-_118513061 10.94 ENSRNOT00000043338
Il13ra2
interleukin 13 receptor subunit alpha 2
chr6_-_94980004 10.45 ENSRNOT00000006373
Rtn1
reticulon 1
chr10_+_57040267 9.88 ENSRNOT00000026207
Arrb2
arrestin, beta 2
chr13_+_83996080 9.77 ENSRNOT00000004403
ENSRNOT00000070958
Cd247
Cd247 molecule
chrX_+_65566047 9.67 ENSRNOT00000092103
Heph
hephaestin
chr14_-_44845218 7.68 ENSRNOT00000004003
Klhl5
kelch-like family member 5
chr1_+_101214593 7.44 ENSRNOT00000028086
Tead2
TEA domain transcription factor 2
chr15_+_18399733 7.33 ENSRNOT00000061158
Fam107a
family with sequence similarity 107, member A
chr5_+_121952977 6.69 ENSRNOT00000008278
Pde4b
phosphodiesterase 4B
chr5_+_147714163 6.62 ENSRNOT00000012663
Marcksl1
MARCKS-like 1
chr13_+_51972974 6.31 ENSRNOT00000008164
Arl8a
ADP-ribosylation factor like GTPase 8A
chr6_-_92527711 5.98 ENSRNOT00000007529
Nin
ninein
chr3_+_72134731 5.92 ENSRNOT00000083592
Ypel4
yippee-like 4
chr3_+_149144795 5.73 ENSRNOT00000015482
Dnmt3b
DNA methyltransferase 3 beta
chr3_+_162357356 5.41 ENSRNOT00000030119
Eya2
EYA transcriptional coactivator and phosphatase 2
chr1_-_48825364 5.37 ENSRNOT00000024213
Agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4
chrX_-_159891326 5.26 ENSRNOT00000001154
Rbmx
RNA binding motif protein, X-linked
chr15_+_18399515 5.15 ENSRNOT00000071273
Fam107a
family with sequence similarity 107, member A
chr10_+_56453877 5.05 ENSRNOT00000031640
Plscr3
phospholipid scramblase 3
chr19_+_46733633 4.82 ENSRNOT00000016307
Clec3a
C-type lectin domain family 3, member A
chr8_+_2604962 4.72 ENSRNOT00000009993
Casp1
caspase 1
chr16_+_83206004 4.68 ENSRNOT00000018870
Ankrd10
ankyrin repeat domain 10
chr20_+_3558827 4.65 ENSRNOT00000088130
Ddr1
discoidin domain receptor tyrosine kinase 1
chr5_-_147953093 4.28 ENSRNOT00000075270
Khdrbs1
KH RNA binding domain containing, signal transduction associated 1
chr15_+_33600102 4.24 ENSRNOT00000022664
Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr2_-_236431596 4.10 ENSRNOT00000055570
ENSRNOT00000089674
Cyp2u1
cytochrome P450, family 2, subfamily u, polypeptide 1
chrX_+_18489597 3.95 ENSRNOT00000059744
LOC681355
similar to potassium channel tetramerisation domain containing 12b
chr10_+_110445797 3.65 ENSRNOT00000054920
Narf
nuclear prelamin A recognition factor
chr6_-_18351536 3.56 ENSRNOT00000061588
Crnkl1
crooked neck pre-mRNA splicing factor 1
chr6_+_44009872 3.32 ENSRNOT00000082657
Mboat2
membrane bound O-acyltransferase domain containing 2
chr10_-_83655182 3.18 ENSRNOT00000007897
Abi3
ABI family, member 3
chr20_+_13670066 3.07 ENSRNOT00000031400
LOC103694874
stromelysin-3
chr4_+_13405136 2.95 ENSRNOT00000091004
Gnai1
G protein subunit alpha i1
chr15_+_33600337 2.92 ENSRNOT00000075965
Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr5_+_101526551 2.86 ENSRNOT00000015254
Snapc3
small nuclear RNA activating complex, polypeptide 3
chr7_-_59514939 2.73 ENSRNOT00000085579
Kcnmb4
potassium calcium-activated channel subfamily M regulatory beta subunit 4
chr1_-_170628915 2.67 ENSRNOT00000042865
Dchs1
dachsous cadherin-related 1
chr3_-_118051289 2.52 ENSRNOT00000011551
Secisbp2l
SECIS binding protein 2-like
chr15_-_28672530 2.30 ENSRNOT00000022593
ENSRNOT00000087722
Chd8
chromodomain helicase DNA binding protein 8
chr16_-_69961162 2.26 ENSRNOT00000074955
Prrg3
proline rich and Gla domain 3
chr17_+_42168263 2.26 ENSRNOT00000047422
LOC100360654
ribosomal protein L37-like
chr4_-_77347011 2.24 ENSRNOT00000008149
Ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr19_+_755460 2.23 ENSRNOT00000076560
Dync1li2
dynein, cytoplasmic 1 light intermediate chain 2
chr5_+_148781222 2.19 ENSRNOT00000015831
Pum1
pumilio RNA-binding family member 1
chr11_-_31213787 2.19 ENSRNOT00000002800
Paxbp1
PAX3 and PAX7 binding protein 1
chr1_-_170594168 2.15 ENSRNOT00000026280
Tpp1
tripeptidyl peptidase 1
chr18_+_30909490 2.15 ENSRNOT00000026967
Pcdhgb8
protocadherin gamma subfamily B, 8
chr9_+_46657575 1.91 ENSRNOT00000083322
Map4k4
mitogen-activated protein kinase kinase kinase kinase 4
chr3_-_5976244 1.75 ENSRNOT00000009893
Vav2
vav guanine nucleotide exchange factor 2
chr1_-_169005190 1.70 ENSRNOT00000043719
Hbe1
hemoglobin subunit epsilon 1
chr12_+_23789638 1.68 ENSRNOT00000001954
ENSRNOT00000084730
Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
chr6_+_108820774 1.67 ENSRNOT00000089683
ENSRNOT00000080038
ENSRNOT00000006492
Ylpm1
YLP motif containing 1
chr6_+_106052212 1.63 ENSRNOT00000010626
Sipa1l1
signal-induced proliferation-associated 1 like 1
chrX_-_14220662 1.38 ENSRNOT00000045753
Srpx
sushi-repeat-containing protein, X-linked
chr2_-_250235435 1.34 ENSRNOT00000088618
Lmo4
LIM domain only 4
chr3_+_95715193 1.17 ENSRNOT00000089525
Pax6
paired box 6
chr8_+_69971778 1.13 ENSRNOT00000058007
ENSRNOT00000037941
ENSRNOT00000050649
Megf11
multiple EGF-like-domains 11
chr3_-_3541947 1.11 ENSRNOT00000024786
Nacc2
NACC family member 2
chr10_-_90415070 1.04 ENSRNOT00000055179
Itga2b
integrin subunit alpha 2b
chr7_-_12405022 0.98 ENSRNOT00000021648
Cirbp
cold inducible RNA binding protein
chr7_-_60416925 0.67 ENSRNOT00000008193
Cpsf6
cleavage and polyadenylation specific factor 6
chr7_-_98197087 0.48 ENSRNOT00000010484
ENSRNOT00000079961
Klhl38
kelch-like family member 38
chr18_+_60392376 0.35 ENSRNOT00000023890
Nedd4l
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr1_+_264670841 0.33 ENSRNOT00000034814
ENSRNOT00000082412
Slf2
SMC5-SMC6 complex localization factor 2
chr18_+_15467870 0.28 ENSRNOT00000091696
B4galt6
beta-1,4-galactosyltransferase 6
chr10_+_75365822 0.09 ENSRNOT00000055705
Vezf1
vascular endothelial zinc finger 1
chr1_+_190671696 0.06 ENSRNOT00000084934
AABR07005633.1

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.9 GO:1904685 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) positive regulation of metalloendopeptidase activity(GO:1904685)
3.0 11.9 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
2.5 9.9 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
1.9 5.7 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
1.4 4.3 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
1.2 4.7 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
1.1 6.7 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
1.1 10.9 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
1.1 13.0 GO:0046549 amacrine cell differentiation(GO:0035881) retinal rod cell development(GO:0046548) retinal cone cell development(GO:0046549)
0.9 2.7 GO:0003192 mitral valve formation(GO:0003192) condensed mesenchymal cell proliferation(GO:0072137)
0.9 14.8 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.7 6.0 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.7 3.6 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.6 5.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.6 5.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.5 4.7 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.4 1.2 GO:0003322 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.4 2.2 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834) response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.4 7.4 GO:0048368 lateral mesoderm development(GO:0048368)
0.3 5.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.3 2.5 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.3 2.2 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.2 7.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 2.2 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.2 2.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.2 1.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.2 9.8 GO:0070207 protein homotrimerization(GO:0070207)
0.2 3.0 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.2 4.6 GO:0006825 copper ion transport(GO:0006825)
0.2 5.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 2.7 GO:0005513 detection of calcium ion(GO:0005513)
0.1 3.1 GO:0030574 collagen catabolic process(GO:0030574)
0.1 2.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 1.7 GO:0015671 oxygen transport(GO:0015671)
0.1 0.3 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.1 1.0 GO:0070417 cellular response to cold(GO:0070417)
0.1 1.9 GO:0070571 negative regulation of neuron projection regeneration(GO:0070571)
0.1 1.3 GO:0042659 regulation of cell fate specification(GO:0042659)
0.1 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 9.8 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.1 2.2 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.1 GO:0010842 retina layer formation(GO:0010842)
0.0 1.7 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 1.6 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 3.9 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 4.7 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.0 12.5 GO:0001558 regulation of cell growth(GO:0001558)
0.0 1.7 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.0 1.0 GO:0070527 platelet aggregation(GO:0070527)
0.0 3.3 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.3 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.7 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 3.2 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.4 GO:0071149 TEAD-2-YAP complex(GO:0071149)
2.3 13.9 GO:0033269 internode region of axon(GO:0033269)
1.2 9.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
1.1 5.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.9 4.7 GO:0097169 IPAF inflammasome complex(GO:0072557) NLRP1 inflammasome complex(GO:0072558) AIM2 inflammasome complex(GO:0097169)
0.9 6.0 GO:0036449 microtubule minus-end(GO:0036449)
0.5 3.7 GO:0005638 lamin filament(GO:0005638)
0.3 6.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 9.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 6.3 GO:0051233 spindle midzone(GO:0051233)
0.2 13.1 GO:0005871 kinesin complex(GO:0005871)
0.2 1.7 GO:0005833 hemoglobin complex(GO:0005833)
0.1 9.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 14.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 2.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 5.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 0.7 GO:0042382 paraspeckles(GO:0042382)
0.1 2.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 2.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 3.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 5.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 3.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 14.8 GO:0043209 myelin sheath(GO:0043209)
0.1 1.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 14.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.0 GO:0008305 integrin complex(GO:0008305)
0.0 11.1 GO:0016607 nuclear speck(GO:0016607)
0.0 3.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 2.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 4.3 GO:0098797 plasma membrane protein complex(GO:0098797)
0.0 3.2 GO:0030027 lamellipodium(GO:0030027)
0.0 1.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 3.8 GO:0043235 receptor complex(GO:0043235)
0.0 1.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 10.9 GO:0005730 nucleolus(GO:0005730)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 14.8 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
3.3 9.9 GO:0031826 follicle-stimulating hormone receptor binding(GO:0031762) type 2A serotonin receptor binding(GO:0031826)
2.6 13.0 GO:0008502 melatonin receptor activity(GO:0008502)
2.3 27.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
1.1 5.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.8 4.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.7 3.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.7 4.7 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.6 1.7 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.5 2.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.4 5.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.4 2.5 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.4 7.4 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.4 6.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.4 4.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.3 2.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.3 4.3 GO:0008143 poly(A) binding(GO:0008143)
0.3 1.9 GO:0004111 creatine kinase activity(GO:0004111)
0.2 2.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 5.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 2.2 GO:0070878 primary miRNA binding(GO:0070878)
0.2 1.0 GO:0070051 fibrinogen binding(GO:0070051)
0.2 3.7 GO:0005521 lamin binding(GO:0005521)
0.2 13.1 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.0 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 11.4 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.1 1.2 GO:0003680 AT DNA binding(GO:0003680)
0.1 4.1 GO:0070330 aromatase activity(GO:0070330)
0.1 2.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 11.9 GO:0004519 endonuclease activity(GO:0004519)
0.1 5.3 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 0.3 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.1 7.0 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 1.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 5.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 2.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 5.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 3.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.3 GO:0005516 calmodulin binding(GO:0005516)
0.0 4.8 GO:0030246 carbohydrate binding(GO:0030246)
0.0 10.6 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.3 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 3.3 GO:0016746 transferase activity, transferring acyl groups(GO:0016746)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 10.9 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.5 9.9 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.3 9.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.3 4.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 3.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.9 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 3.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 9.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.5 14.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.4 4.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 9.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.3 7.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 3.3 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.2 6.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 13.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 5.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.2 3.0 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.2 4.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 4.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 2.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.9 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 1.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.0 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 2.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 5.3 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 2.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 2.2 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation