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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Sox3_Sox10

Z-value: 1.18

Motif logo

Transcription factors associated with Sox3_Sox10

Gene Symbol Gene ID Gene Info
ENSRNOG00000011305 SRY box 10

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox10rn6_v1_chr7_-_120403523_1204035230.731.4e-54Click!

Activity profile of Sox3_Sox10 motif

Sorted Z-values of Sox3_Sox10 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_79406381 111.88 ENSRNOT00000022303
ENSRNOT00000058295
ENSRNOT00000058296
ENSRNOT00000022280
myelin basic protein
chr8_+_128824508 94.44 ENSRNOT00000025343
myelin-associated oligodendrocyte basic protein
chr3_+_35014538 73.81 ENSRNOT00000006341
kinesin family member 5C
chr5_+_49311030 71.41 ENSRNOT00000010850
cannabinoid receptor 1
chr9_+_73334618 63.70 ENSRNOT00000092717
microtubule-associated protein 2
chr3_-_44086006 56.06 ENSRNOT00000034449
ENSRNOT00000082604
ermin
chr7_-_136853957 54.96 ENSRNOT00000008985
neural EGFL like 2
chr16_-_39476025 54.95 ENSRNOT00000014312
glycoprotein m6a
chr5_+_64326733 54.91 ENSRNOT00000065775
transmembrane protein with EGF-like and two follistatin-like domains 1
chr7_-_136853154 53.79 ENSRNOT00000087376
neural EGFL like 2
chrX_-_115175299 49.37 ENSRNOT00000074322
doublecortin
chr18_+_30562178 46.36 ENSRNOT00000040998
protocadherin beta-16-like
chr19_+_56220755 44.48 ENSRNOT00000023452
tubulin, beta 3 class III
chr1_+_72860218 42.99 ENSRNOT00000024547
synaptotagmin 5
chr9_-_100253609 42.04 ENSRNOT00000036061
kinesin family member 1A
chr14_-_78308933 37.44 ENSRNOT00000065334
collapsin response mediator protein 1
chr18_-_26211445 35.66 ENSRNOT00000027739
neuronal regeneration related protein
chrX_+_144445795 35.55 ENSRNOT00000048467
similar to melanoma antigen family A, 10
chr3_-_51643140 32.89 ENSRNOT00000006646
sodium voltage-gated channel alpha subunit 3
chr15_+_40665041 32.75 ENSRNOT00000018300
APC membrane recruitment protein 2
chr4_+_110700403 32.60 ENSRNOT00000092379
leucine rich repeat transmembrane neuronal 4
chr7_-_12275609 32.28 ENSRNOT00000086061
APC2, WNT signaling pathway regulator
chr1_+_99762253 31.91 ENSRNOT00000065876
kallikrein related-peptidase 6
chr15_-_43542939 30.48 ENSRNOT00000012996
dihydropyrimidinase-like 2
chr10_+_3411380 29.78 ENSRNOT00000004346
similar to RIKEN cDNA 2900011O08
chr20_-_54517709 27.99 ENSRNOT00000076234
glutamate ionotropic receptor kainate type subunit 2
chr9_+_73433252 27.77 ENSRNOT00000092540
microtubule-associated protein 2
chr3_-_2689084 26.83 ENSRNOT00000020926
prostaglandin D2 synthase
chr15_-_62200837 26.59 ENSRNOT00000017599
protocadherin 8
chr15_+_33600102 26.37 ENSRNOT00000022664
CKLF-like MARVEL transmembrane domain containing 5
chr6_-_147172022 26.30 ENSRNOT00000080675
integrin subunit beta 8
chr1_+_264741911 26.20 ENSRNOT00000019956
semaphorin 4G
chr20_+_40769586 25.56 ENSRNOT00000001079
fatty acid binding protein 7
chr3_-_114307250 25.45 ENSRNOT00000064592
Src homology 2 domain containing F
chr13_-_107831014 24.49 ENSRNOT00000003684
potassium two pore domain channel subfamily K member 2
chr1_-_103256823 23.82 ENSRNOT00000018860
protein tyrosine phosphatase, non-receptor type 5
chr3_-_176816114 22.69 ENSRNOT00000079262
ENSRNOT00000018697
stathmin 3
chr3_-_168018410 22.51 ENSRNOT00000087579
breast carcinoma amplified sequence 1
chr6_-_94980004 22.36 ENSRNOT00000006373
reticulon 1
chr18_+_29993361 21.60 ENSRNOT00000075810
protocadherin alpha 4
chr1_+_81372650 20.91 ENSRNOT00000088829
zinc finger protein 428
chr9_+_9961021 20.68 ENSRNOT00000075767
tubulin, beta 4A class IVa
chrX_-_134866210 20.39 ENSRNOT00000005331
apelin
chr2_-_187401786 20.38 ENSRNOT00000025624
hyaluronan and proteoglycan link protein 2
chr19_-_26053762 19.70 ENSRNOT00000004646
microtubule associated serine/threonine kinase 1
chrX_+_62754634 19.10 ENSRNOT00000016669
phosphate cytidylyltransferase 1, choline, beta
chr4_+_136512201 19.02 ENSRNOT00000051645
contactin 6
chr5_-_167244786 18.72 ENSRNOT00000051309
carbonic anhydrase 6
chr9_-_61810417 18.65 ENSRNOT00000020910
raftlin family member 2
chr2_+_74360622 18.25 ENSRNOT00000014013
cadherin 18
chr8_+_60709851 18.22 ENSRNOT00000021817
reticulocalbin 2
chr3_+_160935709 18.08 ENSRNOT00000019688
dysbindin domain containing 2
chr18_+_15467870 17.93 ENSRNOT00000091696
beta-1,4-galactosyltransferase 6
chr14_-_82048251 17.91 ENSRNOT00000074734
N-acetyltransferase 8-like
chr13_-_91872954 17.80 ENSRNOT00000004613
ENSRNOT00000079263
cell adhesion molecule 3
chr18_-_69944632 17.63 ENSRNOT00000047271
mitogen-activated protein kinase 4
chr12_+_40018937 17.61 ENSRNOT00000001697
cut-like homeobox 2
chr5_-_109651730 17.51 ENSRNOT00000093032
ELAV like RNA binding protein 2
chr8_+_44136496 17.44 ENSRNOT00000087022
sodium voltage-gated channel beta subunit 3
chr6_-_147172813 17.42 ENSRNOT00000066545
integrin subunit beta 8
chr11_+_86512797 17.06 ENSRNOT00000051680
glycoprotein Ib platelet beta subunit
chr8_-_62987182 16.84 ENSRNOT00000070885
immunoglobulin superfamily containing leucine-rich repeat 2
chr13_-_82758004 16.63 ENSRNOT00000003932
ATPase Na+/K+ transporting subunit beta 1
chrX_+_62727755 16.55 ENSRNOT00000077055
phosphate cytidylyltransferase 1, choline, beta
chr5_+_152680407 16.52 ENSRNOT00000076864
stathmin 1
chr18_+_30010918 16.51 ENSRNOT00000084132
protocadherin alpha 4
chr2_-_41785792 16.48 ENSRNOT00000015871
RAB3C, member RAS oncogene family
chrX_+_39711201 16.39 ENSRNOT00000080512
ENSRNOT00000009802
connector enhancer of kinase suppressor of Ras 2
chr12_-_35979193 16.39 ENSRNOT00000071104
transmembrane protein 132B
chr5_-_48165317 16.29 ENSRNOT00000088179
ankyrin repeat domain 6
chr4_+_113968995 16.25 ENSRNOT00000079511
rhotekin
chrX_-_29648359 16.20 ENSRNOT00000086721
ENSRNOT00000006777
glycoprotein m6b
chr3_+_131351587 16.07 ENSRNOT00000010835
BTB domain containing 3
chr3_+_152571121 15.87 ENSRNOT00000087289
ENSRNOT00000080543
ENSRNOT00000083476
erythrocyte membrane protein band 4.1-like 1
chr12_-_13668515 15.79 ENSRNOT00000086847
fascin actin-bundling protein 1
chr12_-_29743705 15.72 ENSRNOT00000001185
calneuron 1
chr18_+_30381322 15.53 ENSRNOT00000027216
protocadherin beta 3
chr7_-_83670356 15.53 ENSRNOT00000005584
syntabulin
chrX_-_134719097 15.53 ENSRNOT00000068478
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr3_+_155160481 15.51 ENSRNOT00000021133
protein phosphatase 1, regulatory subunit 16B
chr2_-_29768750 15.27 ENSRNOT00000023460
microtubule-associated protein 1B
chr16_+_22250470 15.19 ENSRNOT00000015799
leucine zipper tumor suppressor 1
chr20_+_3558827 15.06 ENSRNOT00000088130
discoidin domain receptor tyrosine kinase 1
chr4_+_22445414 15.02 ENSRNOT00000087657
ENSRNOT00000030224
RUN domain containing 3B
chr5_-_86696388 14.99 ENSRNOT00000007812
multiple EGF-like-domains 9
chr1_-_170404056 14.87 ENSRNOT00000024402
amyloid beta precursor protein binding family B member 1
chr12_+_28381982 14.67 ENSRNOT00000076101
Williams-Beuren syndrome chromosome region 17
chr7_+_64672722 14.57 ENSRNOT00000064448
ENSRNOT00000005539
glutamate receptor interacting protein 1
chr3_-_64543100 14.43 ENSRNOT00000025803
zinc finger protein 385B
chr3_+_159823878 14.16 ENSRNOT00000011748
ganglioside-induced differentiation-associated protein 1-like 1
chr17_+_31441630 14.04 ENSRNOT00000083705
ENSRNOT00000023582
tubulin, beta 2B class IIb
chr2_-_226779266 13.97 ENSRNOT00000019244
formin binding protein 1-like
chr16_+_22361998 13.93 ENSRNOT00000016193
solute carrier family 18 member A1
chr9_-_28973246 13.93 ENSRNOT00000091865
ENSRNOT00000015453
regulating synaptic membrane exocytosis 1
chr10_+_45289741 13.85 ENSRNOT00000066190
histone cluster 3, H2ba
chr4_+_110699557 13.82 ENSRNOT00000030588
ENSRNOT00000092261
leucine rich repeat transmembrane neuronal 4
chr17_+_13670520 13.67 ENSRNOT00000019442
SHC adaptor protein 3
chr11_+_74834050 13.48 ENSRNOT00000002333
ATPase 13A4
chr7_-_140640953 13.45 ENSRNOT00000083156
tubulin, alpha 1A
chr15_+_33600337 13.39 ENSRNOT00000075965
CKLF-like MARVEL transmembrane domain containing 5
chr20_+_10123651 13.31 ENSRNOT00000001559
phosphodiesterase 9A
chr6_-_51019407 13.28 ENSRNOT00000011659
G protein-coupled receptor 22
chr5_-_147412705 13.08 ENSRNOT00000010688
similar to mKIAA1522 protein
chr10_-_51576376 13.06 ENSRNOT00000004829
Rho GTPase activating protein 44
chr9_-_28972835 12.88 ENSRNOT00000086967
ENSRNOT00000079684
regulating synaptic membrane exocytosis 1
chr19_+_38601786 12.81 ENSRNOT00000087655
zinc finger protein 90
chr3_+_95715193 12.78 ENSRNOT00000089525
paired box 6
chr6_+_105364668 12.63 ENSRNOT00000009513
ENSRNOT00000087090
tetratricopeptide repeat domain 9
chr20_+_20105047 12.62 ENSRNOT00000082181
ankyrin 3
chr12_+_25173005 12.56 ENSRNOT00000033200
ENSRNOT00000091328
CAP-GLY domain containing linker protein 2
chr5_-_9381214 12.47 ENSRNOT00000039237
similar to RIKEN cDNA 3110035E14
chr18_+_30435119 12.28 ENSRNOT00000027190
protocadherin beta 8
chr13_-_49313940 12.24 ENSRNOT00000012190
contactin 2
chrX_+_19243759 12.10 ENSRNOT00000004238
MAGE family member H1
chr9_-_71830730 12.02 ENSRNOT00000019963
crystallin, gamma A
chr1_+_234363994 11.99 ENSRNOT00000018137
RAR-related orphan receptor B
chr16_-_81912738 11.97 ENSRNOT00000087095
MCF.2 cell line derived transforming sequence-like
chr2_-_23909016 11.93 ENSRNOT00000084044
secretory carrier membrane protein 1
chr9_-_75528644 11.84 ENSRNOT00000019283
erb-b2 receptor tyrosine kinase 4
chr15_-_65507968 11.74 ENSRNOT00000046240
calmodulin 2
chr5_+_152681101 11.72 ENSRNOT00000076052
ENSRNOT00000022574
stathmin 1
chr4_-_727691 11.71 ENSRNOT00000008497
sonic hedgehog
chrX_+_6273733 11.67 ENSRNOT00000074275
NDP, norrin cystine knot growth factor
chr4_-_11610518 11.62 ENSRNOT00000066643
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_+_95008311 11.60 ENSRNOT00000077270
tumor protein D52
chr8_-_116893057 11.56 ENSRNOT00000082113
bassoon (presynaptic cytomatrix protein)
chr1_+_25173242 11.53 ENSRNOT00000016518
clavesin 2
chrX_+_70596576 11.43 ENSRNOT00000045082
ENSRNOT00000003741
ENSRNOT00000076079
discs large MAGUK scaffold protein 3
chr6_-_27024129 11.33 ENSRNOT00000012273
dihydropyrimidinase-like 5
chr7_-_78930832 11.11 ENSRNOT00000005668
LDL receptor related protein 12
chr9_+_6966908 11.11 ENSRNOT00000072796
ST6 beta-galactoside alpha-2,6-sialyltransferase 2
chr10_-_74376270 10.95 ENSRNOT00000079311
glycerophosphodiester phosphodiesterase domain containing 1
chr3_-_123849788 10.86 ENSRNOT00000028869
ring finger protein 24
chr2_+_95008477 10.86 ENSRNOT00000015327
tumor protein D52
chr19_+_24329544 10.83 ENSRNOT00000080934
TBC1 domain family member 9
chr14_-_37770059 10.61 ENSRNOT00000029721
solute carrier family 10, member 4
chr11_+_61531571 10.46 ENSRNOT00000093467
ENSRNOT00000002727
ATPase H+ transporting V1 subunit A
chr7_-_140417530 10.44 ENSRNOT00000077884
FK506 binding protein 11
chr1_+_144070754 10.40 ENSRNOT00000079989
SH3 domain-containing GRB2-like 3
chr4_+_86275717 10.28 ENSRNOT00000016414
protein phosphatase 1, regulatory subunit 17
chr7_+_110031696 10.24 ENSRNOT00000012753
KH RNA binding domain containing, signal transduction associated 3
chr4_-_39102807 10.08 ENSRNOT00000052063
thrombospondin type 1 domain containing 7A
chr7_-_59514939 9.99 ENSRNOT00000085579
potassium calcium-activated channel subfamily M regulatory beta subunit 4
chr18_+_30895831 9.89 ENSRNOT00000026985
protocadherin gamma subfamily A, 10
chrX_-_152641679 9.83 ENSRNOT00000080277
gamma-aminobutyric acid type A receptor alpha3 subunit
chr5_-_34813116 9.78 ENSRNOT00000017479
Sodium/potassium transporting ATPase interacting 3
chr16_+_54765325 9.76 ENSRNOT00000065327
ENSRNOT00000086899
myotubularin related protein 7
chr13_-_95250235 9.73 ENSRNOT00000085648
AKT serine/threonine kinase 3
chr14_-_41786084 9.63 ENSRNOT00000059439
glutaredoxin and cysteine rich domain containing 1
chr6_+_73358112 9.60 ENSRNOT00000041373
Rho GTPase activating protein 5
chr6_+_73553210 9.57 ENSRNOT00000006562
A-kinase anchoring protein 6
chr19_+_56136904 9.48 ENSRNOT00000022823
spire-type actin nucleation factor 2
chr18_+_30574627 9.46 ENSRNOT00000060484
protocadherin beta 19
chr15_-_108120279 9.35 ENSRNOT00000090572
dedicator of cytokinesis 9
chr8_+_33239139 9.33 ENSRNOT00000011589
Rho GTPase activating protein 32
chr10_+_43768708 9.30 ENSRNOT00000086218
SH3 binding domain protein 5 like
chr11_+_61531416 9.22 ENSRNOT00000093263
ATPase H+ transporting V1 subunit A
chr6_+_44009872 9.22 ENSRNOT00000082657
membrane bound O-acyltransferase domain containing 2
chr2_-_226779440 9.21 ENSRNOT00000055669
formin binding protein 1-like
chr13_-_43566680 9.16 ENSRNOT00000073921
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A-like
chr14_-_21128505 9.01 ENSRNOT00000004776
RUN and FYVE domain containing 3
chr5_-_62186372 8.94 ENSRNOT00000089789
coronin 2A
chrX_-_123662350 8.69 ENSRNOT00000092624
septin 6
chr3_+_176102351 8.56 ENSRNOT00000013105
collagen type IX alpha 3 chain
chr6_+_147876557 8.52 ENSRNOT00000080090
transmembrane protein 196
chr6_+_43001948 8.33 ENSRNOT00000007374
hippocalcin-like 1
chr5_-_12541019 8.31 ENSRNOT00000091649
suppression of tumorigenicity 18
chrX_+_135348436 8.28 ENSRNOT00000008868
RAB33A, member RAS oncogene family
chr1_-_165382216 8.25 ENSRNOT00000023648
protein phosphatase methylesterase 1
chr10_-_47453442 8.24 ENSRNOT00000050061
ubiquitin specific peptidase 22
chr12_-_19114399 8.19 ENSRNOT00000073099
cytochrome P450, family 3, subfamily a, polypeptide 9
chr5_-_82168347 8.12 ENSRNOT00000084959
ENSRNOT00000084147
astrotactin 2
chr11_-_88092756 8.12 ENSRNOT00000002542
YdjC homolog (bacterial)
chr3_-_15278645 8.11 ENSRNOT00000032204
tubulin tyrosine ligase like11
chr13_-_1946508 7.98 ENSRNOT00000043890
dermatan sulfate epimerase-like
chr10_-_56167426 7.98 ENSRNOT00000013955
ephrin B3
chr11_+_73738433 7.92 ENSRNOT00000002353
transmembrane protein 44
chr10_-_85974644 7.84 ENSRNOT00000006098
ENSRNOT00000082974
calcium voltage-gated channel auxiliary subunit beta 1
chr6_+_145546595 7.76 ENSRNOT00000007112
Rap guanine nucleotide exchange factor 5
chr19_+_755460 7.75 ENSRNOT00000076560
dynein, cytoplasmic 1 light intermediate chain 2
chr10_+_92288910 7.75 ENSRNOT00000006947
ENSRNOT00000045127
microtubule-associated protein tau
chr5_+_147714163 7.74 ENSRNOT00000012663
MARCKS-like 1
chr14_-_81399353 7.69 ENSRNOT00000018340
adducin 1
chr2_-_186245771 7.68 ENSRNOT00000066004
ENSRNOT00000079954
doublecortin-like kinase 2
chr6_+_147876237 7.67 ENSRNOT00000056649
transmembrane protein 196
chr10_-_88670430 7.66 ENSRNOT00000025547
hypocretin neuropeptide precursor
chr2_-_96520137 7.63 ENSRNOT00000066966
zinc finger, C2HC-type containing 1A
chr1_-_213981317 7.61 ENSRNOT00000086238
ENSRNOT00000054869
solute carrier family 25 member 22
chr4_-_150616895 7.58 ENSRNOT00000073562
ankyrin repeat domain 26
chr9_+_49479023 7.51 ENSRNOT00000050922
ENSRNOT00000077111
POU class 3 homeobox 3
chr16_+_48121430 7.48 ENSRNOT00000090839
storkhead box 2
chr14_-_21127868 7.40 ENSRNOT00000020608
ENSRNOT00000092172
RUN and FYVE domain containing 3
chr18_+_14757679 7.40 ENSRNOT00000071364
microtubule-associated protein, RP/EB family, member 2
chr13_-_51076852 7.33 ENSRNOT00000078993
adenosine A1 receptor
chrX_-_15553720 7.28 ENSRNOT00000012646
GRIP1 associated protein 1
chr15_+_18399733 7.26 ENSRNOT00000061158
family with sequence similarity 107, member A
chr2_+_112868707 7.14 ENSRNOT00000017805
neutral cholesterol ester hydrolase 1
chr15_-_6587367 7.12 ENSRNOT00000038449
zinc finger protein 385D
chr4_+_84194347 7.09 ENSRNOT00000084256
chimerin 2
chr3_+_148510779 7.05 ENSRNOT00000012156
XK related 7

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox3_Sox10

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
37.3 111.9 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) positive regulation of metalloendopeptidase activity(GO:1904685)
23.8 71.4 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
18.5 73.8 GO:0098961 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
9.1 108.7 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
8.9 26.8 GO:0031632 positive regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031632)
8.7 34.7 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
8.2 24.5 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
7.1 21.2 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
6.7 26.8 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
6.0 30.1 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
5.8 5.8 GO:0010643 cell communication by chemical coupling(GO:0010643)
5.5 16.6 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
5.2 15.5 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
5.1 20.4 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
4.8 19.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
4.6 13.9 GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769)
4.5 17.9 GO:0051586 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
4.3 12.8 GO:0021917 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
4.1 37.0 GO:1904116 response to vasopressin(GO:1904116)
4.1 12.2 GO:0060167 clustering of voltage-gated potassium channels(GO:0045163) regulation of adenosine receptor signaling pathway(GO:0060167)
4.0 23.8 GO:2001025 positive regulation of response to drug(GO:2001025)
3.9 15.8 GO:0030035 microspike assembly(GO:0030035)
3.7 7.3 GO:0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
3.6 35.7 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
3.6 46.4 GO:0097113 AMPA glutamate receptor clustering(GO:0097113)
3.3 23.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
3.2 9.5 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
3.2 12.6 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
3.1 31.1 GO:0046684 response to pyrethroid(GO:0046684)
3.1 18.6 GO:0033227 dsRNA transport(GO:0033227)
3.0 21.3 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
3.0 115.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
2.7 8.1 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
2.6 10.5 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
2.6 20.5 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
2.5 48.3 GO:0021860 pyramidal neuron development(GO:0021860)
2.5 17.4 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
2.5 24.5 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
2.4 43.7 GO:0001573 ganglioside metabolic process(GO:0001573)
2.4 7.3 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
2.3 16.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
2.3 11.6 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
2.3 6.9 GO:0018201 peptidyl-glycine modification(GO:0018201)
2.1 6.4 GO:2000978 auditory receptor cell fate determination(GO:0042668) negative regulation of pro-B cell differentiation(GO:2000974) negative regulation of forebrain neuron differentiation(GO:2000978)
2.0 8.2 GO:0009822 lipid hydroxylation(GO:0002933) alkaloid catabolic process(GO:0009822)
2.0 14.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
2.0 8.0 GO:0016198 axon choice point recognition(GO:0016198)
2.0 11.8 GO:0007262 STAT protein import into nucleus(GO:0007262)
1.9 5.8 GO:0002572 pro-T cell differentiation(GO:0002572)
1.9 11.6 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
1.9 26.9 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
1.9 7.5 GO:0072021 ascending thin limb development(GO:0072021) metanephric ascending thin limb development(GO:0072218)
1.9 3.7 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
1.9 20.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.8 3.7 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
1.8 5.5 GO:1990402 embryonic liver development(GO:1990402)
1.7 28.0 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
1.7 1.7 GO:0001998 angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
1.7 25.6 GO:0060134 prepulse inhibition(GO:0060134)
1.7 30.5 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
1.6 9.6 GO:0048664 neuron fate determination(GO:0048664)
1.6 8.0 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
1.6 15.6 GO:0018095 protein polyglutamylation(GO:0018095)
1.6 6.2 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
1.5 54.9 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
1.5 4.6 GO:0046952 polyprenol biosynthetic process(GO:0016094) ketone body catabolic process(GO:0046952)
1.5 4.5 GO:0019086 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086) positive regulation of transcription by glucose(GO:0046016)
1.5 9.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
1.5 20.7 GO:0031111 negative regulation of microtubule polymerization or depolymerization(GO:0031111)
1.5 4.4 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
1.4 6.9 GO:0044691 tooth eruption(GO:0044691)
1.4 4.1 GO:0032472 Golgi calcium ion transport(GO:0032472)
1.3 39.8 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
1.3 27.8 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
1.3 10.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
1.3 7.7 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
1.3 5.1 GO:0042339 keratan sulfate metabolic process(GO:0042339)
1.3 17.6 GO:0007614 short-term memory(GO:0007614)
1.3 6.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
1.2 4.8 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
1.2 5.8 GO:0050975 sensory perception of touch(GO:0050975)
1.2 3.5 GO:0009609 response to symbiotic bacterium(GO:0009609)
1.1 11.4 GO:0046710 GDP metabolic process(GO:0046710)
1.1 13.3 GO:0046069 cGMP catabolic process(GO:0046069)
1.1 4.4 GO:0009597 detection of virus(GO:0009597)
1.1 162.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.1 5.4 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
1.1 3.3 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
1.0 4.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
1.0 16.2 GO:0008090 retrograde axonal transport(GO:0008090)
1.0 12.0 GO:0046548 retinal rod cell development(GO:0046548)
1.0 9.9 GO:0035865 cellular response to potassium ion(GO:0035865)
1.0 36.0 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
1.0 4.8 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
1.0 5.8 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
1.0 2.9 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
1.0 3.8 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.9 2.8 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.9 2.8 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.9 3.6 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.9 2.6 GO:0051490 negative regulation of filopodium assembly(GO:0051490) positive regulation of phospholipid catabolic process(GO:0060697)
0.8 6.6 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.8 19.4 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.8 14.4 GO:0097503 sialylation(GO:0097503)
0.8 6.3 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.8 10.0 GO:0005513 detection of calcium ion(GO:0005513)
0.8 2.3 GO:0045751 regulation of Toll signaling pathway(GO:0008592) negative regulation of Toll signaling pathway(GO:0045751)
0.8 7.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.8 9.8 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.7 2.2 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.7 5.2 GO:0000103 sulfate assimilation(GO:0000103)
0.7 2.8 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.7 6.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.7 4.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.7 6.8 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.6 18.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.6 1.9 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.6 19.7 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.6 35.5 GO:0031103 axon regeneration(GO:0031103)
0.6 2.4 GO:0021502 neural fold elevation formation(GO:0021502)
0.6 2.9 GO:0036438 maintenance of lens transparency(GO:0036438)
0.6 7.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.6 2.3 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.5 7.6 GO:0001675 acrosome assembly(GO:0001675)
0.5 1.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.5 5.6 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.5 2.0 GO:0010157 epidermal cell fate specification(GO:0009957) response to chlorate(GO:0010157)
0.5 7.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.5 15.2 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.5 2.0 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.5 11.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.5 4.9 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.5 13.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.5 15.8 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.4 1.8 GO:0021637 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.4 1.3 GO:0043382 defense response to nematode(GO:0002215) memory T cell activation(GO:0035709) positive regulation of memory T cell differentiation(GO:0043382) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.4 5.6 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.4 1.7 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.4 11.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.4 4.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.4 2.9 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.4 12.1 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.4 3.3 GO:0043587 tongue morphogenesis(GO:0043587)
0.4 4.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.4 1.7 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.4 6.9 GO:0045793 positive regulation of cell size(GO:0045793)
0.4 4.0 GO:0048148 behavioral response to cocaine(GO:0048148)
0.4 14.3 GO:0045773 positive regulation of axon extension(GO:0045773)
0.4 10.7 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.4 3.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.4 1.2 GO:1901091 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.4 3.5 GO:0098880 maintenance of postsynaptic specialization structure(GO:0098880) maintenance of postsynaptic density structure(GO:0099562)
0.4 1.6 GO:1904008 response to monosodium glutamate(GO:1904008)
0.4 7.6 GO:0046621 negative regulation of organ growth(GO:0046621)
0.4 1.9 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.4 9.6 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.4 2.2 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.4 2.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.4 0.7 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.4 54.2 GO:0007411 axon guidance(GO:0007411)
0.3 2.1 GO:0035330 regulation of hippo signaling(GO:0035330)
0.3 6.9 GO:0003417 growth plate cartilage development(GO:0003417)
0.3 5.9 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.3 2.0 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.3 9.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.3 2.3 GO:0009838 abscission(GO:0009838)
0.3 2.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.3 13.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.3 1.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.3 12.4 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.3 1.5 GO:0042989 sequestering of actin monomers(GO:0042989)
0.3 2.1 GO:0071000 response to magnetism(GO:0071000)
0.3 2.9 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.3 0.9 GO:0060816 random inactivation of X chromosome(GO:0060816) regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.3 1.9 GO:0071910 determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.3 12.0 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.3 6.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.3 2.3 GO:0035900 response to isolation stress(GO:0035900)
0.3 1.0 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.3 2.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.3 2.8 GO:0006527 arginine catabolic process(GO:0006527)
0.2 2.5 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.2 27.2 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.2 14.7 GO:0021987 cerebral cortex development(GO:0021987)
0.2 2.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 8.4 GO:0007340 acrosome reaction(GO:0007340)
0.2 2.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.2 25.9 GO:0008360 regulation of cell shape(GO:0008360)
0.2 6.6 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.2 3.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.2 5.3 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.2 0.6 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 4.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.2 18.8 GO:0001764 neuron migration(GO:0001764)
0.2 7.9 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.2 1.0 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.2 10.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.2 1.3 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.2 1.0 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.2 1.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 1.2 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.2 3.3 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.2 1.2 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.2 9.6 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1 0.7 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.1 0.7 GO:0010991 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.9 GO:0048539 bone marrow development(GO:0048539)
0.1 3.9 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 0.4 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 2.2 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.1 1.7 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.1 1.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 13.1 GO:0019882 antigen processing and presentation(GO:0019882)
0.1 4.7 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 2.1 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 1.5 GO:0051601 exocyst localization(GO:0051601)
0.1 3.1 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.1 5.5 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.1 1.9 GO:0032274 gonadotropin secretion(GO:0032274)
0.1 0.7 GO:0051013 microtubule severing(GO:0051013)
0.1 1.5 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 1.1 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.9 GO:0014047 glutamate secretion(GO:0014047)
0.1 4.2 GO:0016574 histone ubiquitination(GO:0016574)
0.1 2.9 GO:0048678 response to axon injury(GO:0048678)
0.1 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 1.6 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 1.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 7.2 GO:0007605 sensory perception of sound(GO:0007605)
0.1 6.8 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 0.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 1.2 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.1 2.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 2.5 GO:0034766 negative regulation of ion transmembrane transport(GO:0034766)
0.1 1.1 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.1 0.5 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.2 GO:0016598 protein arginylation(GO:0016598)
0.1 0.4 GO:0070417 cellular response to cold(GO:0070417)
0.1 1.0 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 2.0 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 10.0 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.1 2.8 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.2 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:0000105 histidine biosynthetic process(GO:0000105)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.7 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.4 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.9 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 1.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 1.0 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 2.3 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.8 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.1 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.6 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 2.4 GO:0006887 exocytosis(GO:0006887)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
31.4 188.6 GO:0033269 internode region of axon(GO:0033269)
14.6 43.7 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
10.2 91.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
8.6 43.0 GO:1990769 proximal neuron projection(GO:1990769)
5.0 14.9 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
4.9 73.8 GO:0035253 ciliary rootlet(GO:0035253)
4.8 38.4 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
4.8 14.4 GO:0005594 collagen type IX trimer(GO:0005594)
4.7 28.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
4.1 12.3 GO:0060187 cell pole(GO:0060187)
3.9 15.8 GO:0044393 microspike(GO:0044393)
3.5 14.1 GO:0045298 tubulin complex(GO:0045298)
3.5 24.5 GO:0044305 calyx of Held(GO:0044305)
3.2 9.6 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
2.9 8.7 GO:0032173 septin collar(GO:0032173)
2.5 50.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
2.4 7.3 GO:0098837 postsynaptic recycling endosome(GO:0098837)
2.4 23.8 GO:1990635 proximal dendrite(GO:1990635)
1.9 63.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
1.8 18.3 GO:0097433 dense body(GO:0097433)
1.8 23.6 GO:0016342 catenin complex(GO:0016342)
1.7 64.6 GO:0044295 axonal growth cone(GO:0044295)
1.6 19.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
1.5 24.9 GO:0033268 node of Ranvier(GO:0033268)
1.4 5.7 GO:1990357 terminal web(GO:1990357)
1.4 16.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.2 110.7 GO:0042734 presynaptic membrane(GO:0042734)
1.2 4.8 GO:0031021 interphase microtubule organizing center(GO:0031021)
1.2 11.6 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
1.1 8.9 GO:0016589 NURF complex(GO:0016589)
1.0 2.9 GO:1990826 nucleoplasmic periphery of the nuclear pore complex(GO:1990826)
0.9 5.6 GO:0032059 bleb(GO:0032059)
0.8 15.3 GO:0043196 varicosity(GO:0043196)
0.8 10.3 GO:0000124 SAGA complex(GO:0000124)
0.8 7.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.7 9.6 GO:0060091 kinocilium(GO:0060091)
0.7 29.4 GO:0031941 filamentous actin(GO:0031941)
0.7 2.2 GO:0008537 proteasome activator complex(GO:0008537)
0.7 29.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.7 38.0 GO:0005871 kinesin complex(GO:0005871)
0.7 5.0 GO:0097524 sperm plasma membrane(GO:0097524)
0.7 3.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.7 18.9 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.7 219.5 GO:0005874 microtubule(GO:0005874)
0.7 19.3 GO:0035371 microtubule plus-end(GO:0035371)
0.7 11.9 GO:0042589 zymogen granule membrane(GO:0042589)
0.6 17.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.6 16.6 GO:0048786 presynaptic active zone(GO:0048786)
0.6 100.0 GO:0043204 perikaryon(GO:0043204)
0.6 17.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.6 2.2 GO:0070876 SOSS complex(GO:0070876)
0.5 5.8 GO:0031143 pseudopodium(GO:0031143)
0.5 4.2 GO:0032426 stereocilium tip(GO:0032426)
0.5 1.6 GO:0005899 insulin receptor complex(GO:0005899)
0.5 20.2 GO:0043198 dendritic shaft(GO:0043198)
0.5 1.5 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.5 29.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.5 85.4 GO:0043209 myelin sheath(GO:0043209)
0.5 29.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.5 2.3 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.5 1.4 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.4 1.7 GO:0071008 B cell receptor complex(GO:0019815) U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.4 13.8 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.4 3.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.4 6.4 GO:0051233 spindle midzone(GO:0051233)
0.4 22.1 GO:0031901 early endosome membrane(GO:0031901)
0.4 71.0 GO:0014069 postsynaptic density(GO:0014069)
0.4 1.5 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.4 7.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.3 20.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.3 2.4 GO:0000815 ESCRT III complex(GO:0000815)
0.3 4.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 2.5 GO:0000813 ESCRT I complex(GO:0000813)
0.3 2.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.3 1.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.3 3.8 GO:0034709 methylosome(GO:0034709)
0.3 1.3 GO:0097165 nuclear stress granule(GO:0097165)
0.2 2.8 GO:0000812 Swr1 complex(GO:0000812)
0.2 3.0 GO:0031932 TORC2 complex(GO:0031932)
0.2 1.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.2 21.5 GO:0030427 site of polarized growth(GO:0030427)
0.2 206.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.2 1.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.2 2.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 2.8 GO:0071565 nBAF complex(GO:0071565)
0.2 0.6 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 8.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 5.7 GO:0045171 intercellular bridge(GO:0045171)
0.1 38.0 GO:0043025 neuronal cell body(GO:0043025)
0.1 2.0 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 9.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 2.3 GO:0010369 chromocenter(GO:0010369)
0.1 10.9 GO:0000786 nucleosome(GO:0000786)
0.1 10.0 GO:0008021 synaptic vesicle(GO:0008021)
0.1 2.3 GO:0043197 dendritic spine(GO:0043197)
0.1 5.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 5.0 GO:0005903 brush border(GO:0005903)
0.1 0.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 7.8 GO:0005802 trans-Golgi network(GO:0005802)
0.1 1.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 4.1 GO:0055037 recycling endosome(GO:0055037)
0.1 7.0 GO:0001650 fibrillar center(GO:0001650)
0.1 2.4 GO:0016592 mediator complex(GO:0016592)
0.0 3.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 2.2 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 1.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
17.9 71.4 GO:0004949 cannabinoid receptor activity(GO:0004949)
17.2 206.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
7.4 73.8 GO:0034190 apolipoprotein receptor binding(GO:0034190)
7.1 35.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
5.5 43.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
4.9 24.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
4.6 13.9 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
4.5 17.9 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
4.1 94.3 GO:0002162 dystroglycan binding(GO:0002162)
4.0 28.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
3.9 11.7 GO:0099567 N-terminal myristoylation domain binding(GO:0031997) calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099567)
3.5 14.1 GO:0099609 microtubule lateral binding(GO:0099609)
2.9 20.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
2.9 11.6 GO:0070699 type II activin receptor binding(GO:0070699)
2.8 11.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
2.7 16.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
2.7 8.0 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
2.4 16.8 GO:0045504 dynein heavy chain binding(GO:0045504)
2.4 12.0 GO:0008502 melatonin receptor activity(GO:0008502)
2.4 7.1 GO:0001565 phorbol ester receptor activity(GO:0001565)
2.3 11.7 GO:0043237 laminin-1 binding(GO:0043237)
2.3 16.4 GO:0045503 dynein light chain binding(GO:0045503)
2.3 9.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
2.2 17.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
2.1 46.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
2.0 8.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
1.9 5.8 GO:0031893 vasopressin receptor binding(GO:0031893)
1.9 7.5 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
1.9 5.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
1.8 18.4 GO:0036310 annealing helicase activity(GO:0036310)
1.8 39.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
1.8 10.6 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.7 5.2 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
1.7 108.7 GO:0005080 protein kinase C binding(GO:0005080)
1.7 33.1 GO:0031005 filamin binding(GO:0031005)
1.6 6.6 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
1.6 4.8 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
1.5 7.6 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
1.5 4.6 GO:0016453 C-acetyltransferase activity(GO:0016453)
1.5 7.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
1.4 18.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
1.3 7.9 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
1.3 10.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.3 11.5 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
1.3 16.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
1.2 3.7 GO:0022840 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
1.2 10.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
1.2 11.5 GO:0003680 AT DNA binding(GO:0003680)
1.1 11.4 GO:0004385 guanylate kinase activity(GO:0004385)
1.1 121.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
1.1 73.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
1.0 4.0 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
1.0 52.7 GO:0005504 fatty acid binding(GO:0005504)
1.0 13.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.9 2.8 GO:0052724 inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.9 19.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.9 2.8 GO:0016403 dimethylargininase activity(GO:0016403)
0.9 14.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.9 11.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.9 225.9 GO:0008017 microtubule binding(GO:0008017)
0.9 2.6 GO:0070976 TIR domain binding(GO:0070976)
0.8 5.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.8 17.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.8 14.9 GO:0048156 tau protein binding(GO:0048156)
0.8 14.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.7 2.9 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.7 17.5 GO:0005112 Notch binding(GO:0005112)
0.7 3.6 GO:0008035 high-density lipoprotein particle binding(GO:0008035) very-low-density lipoprotein particle receptor activity(GO:0030229)
0.7 26.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.7 9.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.7 2.0 GO:0005119 smoothened binding(GO:0005119)
0.7 3.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.7 15.3 GO:0031489 myosin V binding(GO:0031489)
0.7 57.3 GO:0015631 tubulin binding(GO:0015631)
0.6 5.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.6 4.2 GO:0043426 MRF binding(GO:0043426)
0.6 59.0 GO:0005262 calcium channel activity(GO:0005262)
0.6 5.9 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.6 2.9 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846) diacylglycerol O-acyltransferase activity(GO:0004144)
0.6 6.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.5 7.1 GO:0042301 phosphate ion binding(GO:0042301)
0.5 11.0 GO:0004622 lysophospholipase activity(GO:0004622)
0.5 76.3 GO:0051015 actin filament binding(GO:0051015)
0.5 21.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.5 6.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.5 12.5 GO:0004707 MAP kinase activity(GO:0004707)
0.5 6.3 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.5 3.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.5 5.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.5 5.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.5 2.9 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.5 13.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.5 3.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.4 9.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.4 9.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.4 2.9 GO:0004673 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
0.4 2.1 GO:0071253 connexin binding(GO:0071253)
0.4 2.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.4 3.5 GO:0098919 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of synapse(GO:0098918) structural constituent of postsynaptic density(GO:0098919)
0.4 1.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.4 4.4 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.4 10.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.4 5.0 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.3 9.8 GO:0052866 phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.3 1.4 GO:0005499 vitamin D binding(GO:0005499)
0.3 6.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.3 2.4 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.3 2.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.3 12.7 GO:0005109 frizzled binding(GO:0005109)
0.3 2.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.3 7.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.3 0.9 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.3 1.5 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.3 8.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.3 4.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.3 2.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.3 10.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.2 26.6 GO:0044325 ion channel binding(GO:0044325)
0.2 1.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 13.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.2 4.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 2.4 GO:0070700 BMP receptor binding(GO:0070700)
0.2 3.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 0.9 GO:0005113 patched binding(GO:0005113)
0.2 0.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 1.1 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.2 3.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 0.7 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 101.8 GO:0005509 calcium ion binding(GO:0005509)
0.2 2.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 4.7 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.2 1.8 GO:0045499 chemorepellent activity(GO:0045499)
0.2 2.3 GO:0046527 glucosyltransferase activity(GO:0046527)
0.1 2.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 11.1 GO:0002039 p53 binding(GO:0002039)
0.1 3.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 1.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 1.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 1.7 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.3 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 5.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 1.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 2.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 4.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 20.6 GO:0005543 phospholipid binding(GO:0005543)
0.1 0.4 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 0.2 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 2.3 GO:0017022 myosin binding(GO:0017022)
0.1 17.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 1.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.7 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 5.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 4.6 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 3.2 GO:0043621 protein self-association(GO:0043621)
0.1 0.8 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.1 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 3.0 GO:0043022 ribosome binding(GO:0043022)
0.1 3.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 11.0 GO:0003924 GTPase activity(GO:0003924)
0.0 4.7 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 3.2 GO:0005516 calmodulin binding(GO:0005516)
0.0 3.8 GO:0005525 GTP binding(GO:0005525)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 4.1 GO:0000287 magnesium ion binding(GO:0000287)
0.0 1.7 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 0.2 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.3 GO:0030546 receptor activator activity(GO:0030546)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 42.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
2.1 43.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
1.7 66.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
1.3 85.4 PID LKB1 PATHWAY LKB1 signaling events
1.1 23.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.9 36.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.9 18.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.9 8.0 PID EPHB FWD PATHWAY EPHB forward signaling
0.9 29.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.7 11.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.6 35.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.6 25.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.6 15.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.6 17.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.5 20.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.5 5.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.5 3.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.5 9.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.4 9.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.3 8.8 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.3 7.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 13.4 PID CDC42 PATHWAY CDC42 signaling events
0.2 14.0 PID NOTCH PATHWAY Notch signaling pathway
0.2 9.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.2 2.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.2 6.3 SIG CHEMOTAXIS Genes related to chemotaxis
0.1 21.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 1.5 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 20.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 4.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 2.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 2.1 PID BARD1 PATHWAY BARD1 signaling events
0.1 0.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 2.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 91.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
4.4 79.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
3.2 51.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
1.9 26.8 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
1.9 24.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
1.4 35.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
1.2 9.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
1.0 12.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
1.0 15.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
1.0 10.9 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
1.0 20.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.9 20.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.9 23.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.9 94.2 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.8 14.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.8 12.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.8 21.5 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.8 19.7 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.8 20.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.8 6.9 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.8 15.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.7 53.6 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.6 16.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.6 11.0 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.6 9.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.5 26.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.5 9.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.5 8.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.4 2.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.4 18.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.4 67.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.4 5.1 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.4 9.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.3 3.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 5.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.3 7.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 9.4 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.2 4.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 2.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 15.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 3.8 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 5.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 7.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 3.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.6 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.1 7.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 4.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 7.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.7 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.1 12.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 2.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 6.0 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.1 2.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.4 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 0.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 1.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.2 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.4 REACTOME MEMBRANE TRAFFICKING Genes involved in Membrane Trafficking