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GSE53960: rat RNA-Seq transcriptomic Bodymap
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Results for Sox1
Z-value: 0.90
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Transcription factors associated with Sox1
| Gene Symbol | Gene ID | Gene Info |
|---|
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_-_81534140 Show fit | 49.65 |
ENSRNOT00000027202
|
testis expressed 101 |
|
| chr10_-_5533695 Show fit | 44.12 |
ENSRNOT00000051564
|
ribosomal protein L39-like |
|
| chr2_+_138194136 Show fit | 39.75 |
ENSRNOT00000014928
|
similar to RIKEN cDNA 1700018B24 |
|
| chr18_-_41899450 Show fit | 39.62 |
ENSRNOT00000057099
|
similar to hypothetical protein 4930474N05 |
|
| chr7_+_34744483 Show fit | 37.96 |
ENSRNOT00000007465
|
ubiquitin specific peptidase 44 |
|
| chr7_+_34402738 Show fit | 36.65 |
ENSRNOT00000030985
|
coiled-coil domain containing 38 |
|
| chr16_+_12174370 Show fit | 34.45 |
ENSRNOT00000072045
|
ral guanine nucleotide dissociation stimulator-like |
|
| chr16_+_12976906 Show fit | 33.20 |
ENSRNOT00000029573
|
similar to Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS) |
|
| chr12_+_45319501 Show fit | 33.07 |
ENSRNOT00000090630
ENSRNOT00000041732 |
similar to hypothetical protein 4930474N05 |
|
| chr16_-_12703961 Show fit | 32.53 |
ENSRNOT00000080905
|
similar to hypothetical protein 4930474N05 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Sox1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 162.1 | GO:0007264 | small GTPase mediated signal transduction(GO:0007264) |
| 1.1 | 49.7 | GO:0051281 | positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) |
| 0.1 | 44.1 | GO:0007283 | spermatogenesis(GO:0007283) |
| 1.2 | 39.8 | GO:0006221 | pyrimidine nucleotide biosynthetic process(GO:0006221) |
| 2.7 | 38.0 | GO:1903504 | regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
| 2.3 | 29.5 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 1.2 | 29.2 | GO:0042026 | protein refolding(GO:0042026) |
| 0.4 | 16.6 | GO:0035640 | exploration behavior(GO:0035640) |
| 0.0 | 15.5 | GO:0006470 | protein dephosphorylation(GO:0006470) |
| 5.0 | 14.9 | GO:0003162 | atrioventricular node development(GO:0003162) right ventricular cardiac muscle tissue morphogenesis(GO:0003221) septum secundum development(GO:0003285) His-Purkinje system cell differentiation(GO:0060932) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 49.7 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.4 | 44.1 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 36.3 | GO:0005813 | centrosome(GO:0005813) |
| 2.2 | 29.2 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 1.9 | 17.4 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 0.0 | 16.6 | GO:0045177 | apical part of cell(GO:0045177) |
| 0.1 | 12.1 | GO:0042383 | sarcolemma(GO:0042383) |
| 0.1 | 9.1 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.3 | 8.9 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.2 | 8.5 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 168.0 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.2 | 44.1 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.5 | 38.0 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.3 | 29.2 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.4 | 23.4 | GO:0030145 | manganese ion binding(GO:0030145) |
| 0.1 | 16.6 | GO:0002020 | protease binding(GO:0002020) |
| 0.2 | 14.9 | GO:0001190 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
| 0.3 | 12.1 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.4 | 11.5 | GO:0008392 | arachidonic acid epoxygenase activity(GO:0008392) |
| 0.1 | 9.4 | GO:0004866 | endopeptidase inhibitor activity(GO:0004866) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 17.4 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 15.0 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 10.2 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 3.8 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.1 | 2.3 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.7 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.2 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 3.5 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.2 | 3.2 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.2 | 2.3 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.1 | 2.0 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |