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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Smad1

Z-value: 2.58

Motif logo

Transcription factors associated with Smad1

Gene Symbol Gene ID Gene Info
ENSRNOG00000018483 SMAD family member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Smad1rn6_v1_chr19_+_32188267_32188267-0.303.1e-08Click!

Activity profile of Smad1 motif

Sorted Z-values of Smad1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_219329574 125.69 ENSRNOT00000071109
calcium binding protein 2
chr7_-_71226150 99.16 ENSRNOT00000005875
similar to Retinol dehydrogenase type II (RODH II) (29 k-protein)
chr1_+_83711251 90.25 ENSRNOT00000028237
ENSRNOT00000092008
cytochrome P450, family 2, subfamily a, polypeptide 1
chr6_+_127946686 82.42 ENSRNOT00000082680
Ab1-233
chr16_-_56900052 77.79 ENSRNOT00000017339
macrophage scavenger receptor 1
chr3_-_7141522 74.32 ENSRNOT00000014572
carboxyl ester lipase
chr19_-_64303 67.27 ENSRNOT00000015451
carboxylesterase 2A
chr2_+_186685104 65.06 ENSRNOT00000057022
Cd5 molecule-like
chr3_-_2853272 64.40 ENSRNOT00000023022
ficolin A
chr5_-_78985990 64.18 ENSRNOT00000009248
alpha-1-microglobulin/bikunin precursor
chr11_-_81444375 63.71 ENSRNOT00000058479
ENSRNOT00000078131
ENSRNOT00000080949
ENSRNOT00000080562
ENSRNOT00000084867
kininogen 1
chr2_-_216443518 63.14 ENSRNOT00000022496
amylase, alpha 1A
chr6_-_128003418 56.24 ENSRNOT00000013896
serine (or cysteine) proteinase inhibitor, clade A, member 3C
chr8_+_50525091 53.54 ENSRNOT00000074357
apolipoprotein A1
chr3_-_80543031 51.93 ENSRNOT00000022233
coagulation factor II
chr16_-_7007051 51.75 ENSRNOT00000023984
inter-alpha trypsin inhibitor, heavy chain 3
chr14_-_19191863 51.58 ENSRNOT00000003921
albumin
chr4_+_70776046 51.42 ENSRNOT00000040403
protease, serine 1
chr7_+_71057911 50.81 ENSRNOT00000037218
retinol dehydrogenase 16 (all-trans)
chr1_-_48563776 50.71 ENSRNOT00000023368
plasminogen
chr4_+_153921115 49.89 ENSRNOT00000018821
solute carrier family 6 member 12
chr7_+_70980422 49.80 ENSRNOT00000077912
retinol dehydrogenase 16 (all-trans)
chr4_+_57952982 49.55 ENSRNOT00000014465
carboxypeptidase A1
chr1_+_189364288 48.67 ENSRNOT00000080338
acyl-CoA synthetase medium-chain family member 1
chr4_+_154505826 48.51 ENSRNOT00000044408
murinoglobulin 1
chr11_+_74057361 47.52 ENSRNOT00000048746
carboxypeptidase N subunit 2
chr11_-_81735592 47.12 ENSRNOT00000078203
alpha-2-HS-glycoprotein
chr8_-_50539331 47.08 ENSRNOT00000088997

chr4_+_154391647 46.82 ENSRNOT00000081488
ENSRNOT00000079192
murinoglobulin 1
chr1_+_83933942 46.72 ENSRNOT00000068690
cytochrome P450, family 2, subfamily f, polypeptide 4
chr4_+_109497962 46.24 ENSRNOT00000057869
regenerating family member 1 alpha
chr1_+_279867034 46.09 ENSRNOT00000024164
pancreatic lipase-related protein 1
chr9_+_9721105 45.85 ENSRNOT00000073042
ENSRNOT00000075494
complement C3
chr19_+_85606 45.49 ENSRNOT00000015724
carboxylesterase 2E
chr6_-_127656603 45.27 ENSRNOT00000015516
serpin family A member 11
chr20_-_5805627 44.09 ENSRNOT00000085996
colipase
chr13_+_50164563 42.78 ENSRNOT00000029533
lymphocyte transmembrane adaptor 1
chr16_+_18690649 42.24 ENSRNOT00000015190
methionine adenosyltransferase 1A
chr14_+_20266891 41.94 ENSRNOT00000004174
group specific component
chr1_-_73660593 41.57 ENSRNOT00000038802
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr7_+_71065197 40.90 ENSRNOT00000051075
retinol dehydrogenase 16 (all-trans)
chr10_+_56710965 40.77 ENSRNOT00000087121
asialoglycoprotein receptor 2
chr20_-_2678141 40.53 ENSRNOT00000072377
ENSRNOT00000083833
complement component 4A (Rodgers blood group)
chr8_+_50559126 40.46 ENSRNOT00000024918
apolipoprotein A5
chr4_+_98457810 40.22 ENSRNOT00000074175

chr19_+_15294248 40.19 ENSRNOT00000024622
carboxylesterase 1F
chr1_-_259287684 39.98 ENSRNOT00000054724
cytochrome P450, family 2, subfamily c, polypeptide 22
chr4_+_154676427 39.57 ENSRNOT00000019969
ENSRNOT00000087441
murinoglobulin 1
chr16_+_6970342 39.38 ENSRNOT00000061294
ENSRNOT00000048344
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr6_+_132762280 39.31 ENSRNOT00000004070
solute carrier family 25, member 47
chr10_-_70802782 39.23 ENSRNOT00000045867
chemokine (C-C motif) ligand 6
chr8_+_50537009 38.85 ENSRNOT00000080658
apolipoprotein A4
chr4_+_70614524 38.73 ENSRNOT00000041100
protease, serine 3
chr10_-_66229311 38.21 ENSRNOT00000016897
lectin, galactose binding, soluble 5
chr7_-_123621102 37.84 ENSRNOT00000046024
cytochrome P450, family 2, subfamily d, polypeptide 5
chr14_+_22937421 37.65 ENSRNOT00000065079
similar to Expressed sequence AI788959
chr1_-_170431073 37.58 ENSRNOT00000024710
hemopexin
chr6_-_139997537 37.51 ENSRNOT00000073207

chr1_+_201672528 37.45 ENSRNOT00000093490
deleted in malignant brain tumors 1
chr7_+_3216497 37.31 ENSRNOT00000008909
matrix metallopeptidase 19
chr16_-_7026540 37.06 ENSRNOT00000051751
inter-alpha trypsin inhibitor, heavy chain 1
chr7_-_119689938 36.88 ENSRNOT00000000200
transmembrane protease, serine 6
chr4_-_103258134 36.37 ENSRNOT00000086827

chr14_+_22251499 36.34 ENSRNOT00000087991
ENSRNOT00000002705
UDP glucuronosyltransferase 2 family, polypeptide A1
chr3_-_14112851 36.24 ENSRNOT00000092736
complement C5
chr9_+_74124016 36.22 ENSRNOT00000019023
carbamoyl-phosphate synthase 1
chr15_-_42693694 36.06 ENSRNOT00000022702
gulonolactone (L-) oxidase
chr12_-_20276121 35.66 ENSRNOT00000065873
similar to paired immunoglobin-like type 2 receptor beta
chr1_-_80609836 35.64 ENSRNOT00000091647
ENSRNOT00000046169
apolipoprotein C1
chr4_-_70628470 35.28 ENSRNOT00000029319
trypsin 5
chr17_-_69711689 34.81 ENSRNOT00000041925
aldo-keto reductase family 1, member C12
chr1_+_213577122 34.56 ENSRNOT00000071925
similar to transthyretin (4L369)
chr6_-_127632265 34.49 ENSRNOT00000084157
serpin family A member 1
chr3_-_17081510 34.04 ENSRNOT00000063862

chr4_-_157154120 33.86 ENSRNOT00000056058
complement C1s
chr20_+_295250 33.86 ENSRNOT00000000955
chloride intracellular channel 2
chr4_+_98370797 33.60 ENSRNOT00000031991

chr7_+_14891001 33.41 ENSRNOT00000041034
cytochrome P450, family 4, subfamily f, polypeptide 4
chr16_+_18690246 33.35 ENSRNOT00000081484
methionine adenosyltransferase 1A
chr9_+_100281339 33.34 ENSRNOT00000029127
alanine-glyoxylate aminotransferase
chr2_+_55775274 33.07 ENSRNOT00000018545
complement C9
chr6_-_7961207 32.93 ENSRNOT00000007174
ATP binding cassette subfamily G member 5
chr1_+_65576535 32.76 ENSRNOT00000026575
solute carrier family 27 member 5
chr4_+_99063181 32.64 ENSRNOT00000008840
fatty acid binding protein 1
chr7_-_123630045 32.52 ENSRNOT00000050002
cytochrome P450, family 2, subfamily d, polypeptide 1
chr8_-_62458301 32.25 ENSRNOT00000021653
cytochrome P450, family 1, subfamily a, polypeptide 2
chr1_-_80599572 31.98 ENSRNOT00000024832
apolipoprotein C4
chr14_+_22724070 31.65 ENSRNOT00000089471
UDP glucuronosyltransferase 2 family, polypeptide B10
chr4_+_98371184 31.41 ENSRNOT00000086911

chr5_-_155772040 31.30 ENSRNOT00000036788
chymotrypsin-like elastase family, member 3B
chr19_+_15143794 31.23 ENSRNOT00000085762
carboxylesterase 1F
chr20_-_30947484 31.04 ENSRNOT00000065614
phosphatase domain containing, paladin 1
chr16_-_7007287 30.65 ENSRNOT00000041216
inter-alpha trypsin inhibitor, heavy chain 3
chr10_+_56710464 30.46 ENSRNOT00000065370
ENSRNOT00000064064
asialoglycoprotein receptor 2
chr20_-_4316715 30.38 ENSRNOT00000031704
complement C4B (Chido blood group)
chr4_+_154215250 30.35 ENSRNOT00000072465
murinoglobulin 2
chr10_-_98544447 30.16 ENSRNOT00000073149
ATP binding cassette subfamily A member 6
chr8_-_111761871 30.13 ENSRNOT00000056483
similar to RIKEN cDNA 1300017J02
chr18_+_12008759 30.04 ENSRNOT00000022665
ENSRNOT00000061344
ENSRNOT00000038635
desmoglein 1
chr11_+_80736576 29.97 ENSRNOT00000047678
mannan-binding lectin serine peptidase 1
chr3_+_95233874 29.96 ENSRNOT00000079743
hypothetical protein LOC691083
chr20_-_5806097 29.89 ENSRNOT00000000611
colipase
chr7_+_2689501 29.86 ENSRNOT00000041341
apolipoprotein F
chr7_-_27552078 29.55 ENSRNOT00000059538
stabilin 2
chr11_-_87924816 29.54 ENSRNOT00000031819
serpin family D member 1
chr10_+_14240219 29.40 ENSRNOT00000020233
insulin-like growth factor binding protein, acid labile subunit
chr14_-_80973456 29.34 ENSRNOT00000013257
HGF activator
chr12_+_12227010 29.29 ENSRNOT00000060843
ENSRNOT00000092610
BAI1-associated protein 2-like 1
chr9_+_100156154 29.20 ENSRNOT00000005935
aquaporin 12A
chr15_+_27875911 29.09 ENSRNOT00000013582
purine nucleoside phosphorylase
chr4_-_78458179 29.07 ENSRNOT00000078473
ENSRNOT00000011327
transmembrane protein 176B
chr6_-_138744480 28.75 ENSRNOT00000089387

chr19_+_42097995 28.72 ENSRNOT00000020197
haptoglobin
chr10_-_38774449 28.61 ENSRNOT00000049820
liver-expressed antimicrobial peptide 2
chr10_+_92667869 28.60 ENSRNOT00000082780
ENSRNOT00000073350
integrin subunit beta 3
chr2_+_182006242 28.57 ENSRNOT00000064091
fibrinogen alpha chain
chr16_-_85135859 28.20 ENSRNOT00000075773
macrophage receptor with collagenous structure
chr16_-_81834945 28.17 ENSRNOT00000037806
coagulation factor VII
chr7_+_99158119 28.14 ENSRNOT00000044127
cytochrome P450 2B1
chr1_+_248723397 27.64 ENSRNOT00000072188
mannose-binding protein C-like
chr3_-_2719135 27.51 ENSRNOT00000080257
lipocalin 12
chr7_+_143754892 27.47 ENSRNOT00000085896
sterol O-acyltransferase 2
chr15_-_28081465 27.43 ENSRNOT00000033739
ribonuclease, RNase A family, 6
chr10_-_19574094 27.40 ENSRNOT00000059810
dedicator of cytokinesis 2
chr1_+_166478005 27.27 ENSRNOT00000030037
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr2_-_210703606 27.21 ENSRNOT00000077563
glutathione S-transferase, mu 6-like
chr3_+_16846412 27.11 ENSRNOT00000074266

chr1_-_198104109 27.06 ENSRNOT00000026186
sulfotransferase family 1A member 1
chr7_-_119712888 27.02 ENSRNOT00000077438
interleukin 2 receptor subunit beta
chr5_-_19368431 26.77 ENSRNOT00000012819
cytochrome P450, family 7, subfamily a, polypeptide 1
chr1_+_216677373 26.70 ENSRNOT00000027925
solute carrier family 22, member 18
chr7_+_118685022 26.64 ENSRNOT00000089135
apolipoprotein L, 3
chr1_+_64506735 26.60 ENSRNOT00000086331
NLR family, pyrin domain containing 12
chr9_+_46997798 26.50 ENSRNOT00000087112
ENSRNOT00000082408
interleukin 1 receptor type 1
chr1_-_48559162 26.43 ENSRNOT00000080352
plasminogen
chr19_+_50246402 26.41 ENSRNOT00000018795
hydroxysteroid (17-beta) dehydrogenase 2
chr6_-_139142218 26.38 ENSRNOT00000006975
Immunoglobulin heavy chain (gamma polypeptide)
chr5_+_133620706 26.27 ENSRNOT00000053202
predicted gene 12830
chr1_+_173252058 26.21 ENSRNOT00000073421
similar to very large inducible GTPase 1 isoform A
chr2_-_196113149 26.19 ENSRNOT00000088465
selenium binding protein 1
chr6_+_139486775 26.01 ENSRNOT00000077771

chr1_+_279798187 25.97 ENSRNOT00000024065
pancreatic lipase
chr8_-_23146689 25.91 ENSRNOT00000092200
acid phosphatase 5, tartrate resistant
chr1_-_224389389 25.84 ENSRNOT00000077408
ENSRNOT00000050010
integral membrane transport protein UST4r
chr17_-_8429338 25.83 ENSRNOT00000016390
transforming growth factor, beta induced
chr12_-_21362205 25.71 ENSRNOT00000064787
paired immunoglobulin-like type 2 receptor beta-2
chr9_+_95202632 25.65 ENSRNOT00000025652
UDP glucuronosyltransferase family 1 member A5
chr10_+_103562725 25.56 ENSRNOT00000075199

chr12_-_21670269 25.46 ENSRNOT00000074863
paired immunoglobulin-like type 2 receptor alpha-like
chr1_+_193424812 25.35 ENSRNOT00000019939
aquaporin 8
chr20_-_27782586 25.33 ENSRNOT00000001093
dermatan sulfate epimerase
chr1_+_80880856 25.22 ENSRNOT00000026060
carcinoembryonic antigen-related cell adhesion molecule 20
chr6_-_138507294 25.18 ENSRNOT00000078516

chr13_+_99335020 25.17 ENSRNOT00000029787

chr7_-_123655896 25.13 ENSRNOT00000012413
cytochrome P450, family 2, subfamily d, polypeptide 2
chr6_-_7058314 25.00 ENSRNOT00000045996
3-hydroxyanthranilate 3,4-dioxygenase
chr7_-_117679219 24.97 ENSRNOT00000071522
solute carrier family 39 member 4
chr7_-_142318620 24.94 ENSRNOT00000006351
chymotrypsin-like elastase family, member 1
chr12_-_21923281 24.91 ENSRNOT00000075641
similar to cell surface receptor FDFACT
chr20_+_3990820 24.74 ENSRNOT00000000528
proteasome subunit beta 8
chr14_+_22724399 24.64 ENSRNOT00000002724
UDP glucuronosyltransferase 2 family, polypeptide B10
chr6_-_138321002 24.55 ENSRNOT00000056845
immunoglobulin heavy constant mu
chr1_+_250426158 24.51 ENSRNOT00000067643
APOBEC1 complementation factor
chr3_-_2727616 24.38 ENSRNOT00000061904
complement C8 gamma chain
chr11_-_34142753 24.38 ENSRNOT00000002297
claudin 14
chr7_-_34406318 24.27 ENSRNOT00000007331
amidohydrolase domain containing 1
chr10_+_90085559 24.26 ENSRNOT00000028332
N-acetylglutamate synthase
chr7_+_118692851 24.25 ENSRNOT00000091911
apolipoprotein L3-like
chr17_-_28191436 24.24 ENSRNOT00000000149
lymphocyte antigen 86
chr2_+_186703541 24.11 ENSRNOT00000093342
Fc receptor-like 1
chr3_-_16753987 24.10 ENSRNOT00000091257

chr3_-_72171078 24.09 ENSRNOT00000009817
serpin family G member 1
chr2_+_54466280 24.00 ENSRNOT00000033112
complement C6
chr15_+_57290849 23.89 ENSRNOT00000014909
carboxypeptidase B2
chr4_+_172119331 23.78 ENSRNOT00000010579
microsomal glutathione S-transferase 1
chr17_-_31706523 23.76 ENSRNOT00000071312

chr12_-_21832813 23.71 ENSRNOT00000075280
claudin 3
chr6_-_141147264 23.67 ENSRNOT00000042900
Igh protein-like
chr20_+_13799102 23.62 ENSRNOT00000001669
glutathione S-transferase theta 1
chr7_-_67345295 23.46 ENSRNOT00000087045
ENSRNOT00000005829
arginine vasopressin receptor 1A
chr17_+_78793336 23.46 ENSRNOT00000057898
metallothionein 1
chr12_+_36734372 23.37 ENSRNOT00000001301
scavenger receptor class B, member 1
chr16_-_81822716 23.30 ENSRNOT00000026677
coagulation factor X
chr4_+_175814118 23.28 ENSRNOT00000013409
ENSRNOT00000013514
solute carrier organic anion transporter family, member 1B2
chr17_+_30965942 23.20 ENSRNOT00000060143
PX domain containing 1
chr2_-_210703265 23.12 ENSRNOT00000080228
glutathione S-transferase, mu 6-like
chr6_-_140102325 23.04 ENSRNOT00000072238

chr20_-_2652952 23.00 ENSRNOT00000078871
complement component 4A (Rodgers blood group)
chr20_-_11546046 22.97 ENSRNOT00000068374
hypothetical protein LOC690386
chr1_+_83653234 22.96 ENSRNOT00000085008
ENSRNOT00000084230
ENSRNOT00000090071
cytochrome P450, family 2, subfamily a, polypeptide 1
chr2_+_227455722 22.87 ENSRNOT00000064809
SEC24 homolog D, COPII coat complex component
chr4_-_157155609 22.85 ENSRNOT00000016330
complement C1s
chr14_+_91782354 22.67 ENSRNOT00000005902
IKAROS family zinc finger 1
chr1_+_83744238 22.65 ENSRNOT00000028249
cytochrome P450, family 2, subfamily a, polypeptide 1
chr1_+_199248470 22.61 ENSRNOT00000025933
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr4_-_115332052 22.61 ENSRNOT00000017643
C-type lectin domain family 4, member F
chr7_-_102298522 22.60 ENSRNOT00000006273
alpha-1-B glycoprotein
chr6_-_139102378 22.59 ENSRNOT00000086423

chr12_+_19714324 22.55 ENSRNOT00000072303
similar to cell surface receptor FDFACT
chr9_+_95295701 22.48 ENSRNOT00000025045
UDP glucuronosyltransferase family 1 member A5

Network of associatons between targets according to the STRING database.

First level regulatory network of Smad1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
26.2 78.7 GO:1905225 response to thyrotropin-releasing hormone(GO:1905225)
25.7 77.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
23.5 94.0 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
23.4 70.3 GO:0042197 chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
23.3 69.9 GO:0001905 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
21.7 152.2 GO:0009804 coumarin metabolic process(GO:0009804)
21.4 149.5 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
17.8 53.5 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
16.7 83.4 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
16.5 65.9 GO:0010899 regulation of phosphatidylcholine catabolic process(GO:0010899)
16.1 64.4 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
16.0 63.8 GO:0046951 ketone body biosynthetic process(GO:0046951)
15.6 46.7 GO:0060101 negative regulation of phagocytosis, engulfment(GO:0060101)
14.4 28.7 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
14.2 42.6 GO:0002254 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
13.9 69.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
13.9 41.6 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
13.7 41.1 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) formamide metabolic process(GO:0043606)
13.1 52.6 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
13.0 26.0 GO:0030299 intestinal cholesterol absorption(GO:0030299)
12.9 154.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
12.9 38.7 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
12.5 49.9 GO:0009992 cellular water homeostasis(GO:0009992)
12.1 36.2 GO:0071400 cellular response to oleic acid(GO:0071400)
11.8 35.5 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
11.6 23.3 GO:0046687 response to chromate(GO:0046687)
11.5 34.5 GO:0033986 response to methanol(GO:0033986)
11.4 45.6 GO:0042853 L-alanine catabolic process(GO:0042853)
11.4 136.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
11.2 33.5 GO:1990868 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
11.1 111.3 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
11.0 22.1 GO:0045959 negative regulation of complement activation, classical pathway(GO:0045959)
10.9 32.6 GO:0051977 lysophospholipid transport(GO:0051977)
10.8 53.9 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
10.7 53.6 GO:0006526 arginine biosynthetic process(GO:0006526)
10.7 42.9 GO:0019805 quinolinate biosynthetic process(GO:0019805)
10.7 10.7 GO:0018879 biphenyl metabolic process(GO:0018879)
10.6 42.4 GO:0015879 carnitine transport(GO:0015879)
10.6 42.2 GO:0016554 cytidine to uridine editing(GO:0016554)
10.1 100.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
10.1 30.2 GO:0018916 nitrobenzene metabolic process(GO:0018916)
9.7 29.1 GO:0034418 nicotinamide riboside catabolic process(GO:0006738) urate biosynthetic process(GO:0034418) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
9.6 57.4 GO:0044004 killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
9.4 18.8 GO:0034372 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
9.3 9.3 GO:0015920 lipopolysaccharide transport(GO:0015920)
9.1 82.3 GO:0052697 xenobiotic glucuronidation(GO:0052697)
9.1 27.4 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
9.1 9.1 GO:0002892 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of type IIa hypersensitivity(GO:0001798) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892) positive regulation of type II hypersensitivity(GO:0002894)
9.0 17.9 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
9.0 44.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
8.9 44.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
8.9 17.7 GO:0055073 cadmium ion homeostasis(GO:0055073)
8.8 123.4 GO:0006958 complement activation, classical pathway(GO:0006958)
8.7 26.0 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
8.5 25.6 GO:0003285 septum secundum development(GO:0003285)
8.5 42.5 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
8.4 33.4 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
8.2 24.6 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
8.2 16.4 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
8.1 16.2 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
8.1 24.3 GO:2000422 regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
8.1 32.3 GO:0016098 monoterpenoid metabolic process(GO:0016098)
8.0 31.9 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
8.0 23.9 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
7.9 23.8 GO:0006742 NADP catabolic process(GO:0006742)
7.8 23.5 GO:0002838 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859)
7.8 23.5 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
7.7 7.7 GO:0034014 response to triglyceride(GO:0034014)
7.7 23.0 GO:1990743 protein sialylation(GO:1990743)
7.6 7.6 GO:0046618 drug export(GO:0046618)
7.6 15.3 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
7.5 22.6 GO:0031635 adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635)
7.5 22.5 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
7.4 22.3 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
7.4 29.7 GO:0006565 L-serine catabolic process(GO:0006565)
7.4 37.1 GO:0061113 pancreas morphogenesis(GO:0061113)
7.3 21.9 GO:0010037 response to carbon dioxide(GO:0010037)
7.3 29.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
7.2 36.1 GO:0009115 xanthine catabolic process(GO:0009115)
7.1 14.2 GO:0010034 response to acetate(GO:0010034)
7.1 21.2 GO:0035759 mesangial cell-matrix adhesion(GO:0035759)
7.0 42.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
7.0 21.1 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
7.0 21.0 GO:1903769 negative regulation of cell proliferation in bone marrow(GO:1903769) negative regulation of immunological synapse formation(GO:2000521) negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189)
6.9 6.9 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
6.8 27.2 GO:0033277 abortive mitotic cell cycle(GO:0033277)
6.7 13.5 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
6.7 336.0 GO:0006953 acute-phase response(GO:0006953)
6.6 39.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
6.6 26.2 GO:0048252 lauric acid metabolic process(GO:0048252)
6.5 32.4 GO:0009608 response to symbiont(GO:0009608)
6.2 18.7 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
6.2 18.7 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
6.2 61.5 GO:0018298 protein-chromophore linkage(GO:0018298)
6.0 18.1 GO:1904580 regulation of intracellular mRNA localization(GO:1904580)
6.0 17.9 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
6.0 23.9 GO:0052695 uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585) cellular glucuronidation(GO:0052695)
5.9 29.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
5.9 41.4 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
5.9 11.8 GO:0019364 pyridine nucleotide catabolic process(GO:0019364)
5.8 23.1 GO:0045658 regulation of neutrophil differentiation(GO:0045658)
5.7 11.4 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
5.7 22.8 GO:0019477 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
5.7 45.5 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
5.6 16.8 GO:0034769 basement membrane disassembly(GO:0034769)
5.5 16.4 GO:1901569 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
5.4 16.3 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
5.4 16.3 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
5.4 21.4 GO:0032826 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
5.3 16.0 GO:0006543 glutamine catabolic process(GO:0006543)
5.3 15.9 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
5.3 10.5 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
5.2 15.7 GO:0071579 regulation of zinc ion transport(GO:0071579)
5.1 5.1 GO:2000464 positive regulation of astrocyte chemotaxis(GO:2000464)
5.1 25.5 GO:0042178 xenobiotic catabolic process(GO:0042178)
5.0 20.2 GO:0097350 neutrophil clearance(GO:0097350)
5.0 10.1 GO:0039019 pronephric nephron development(GO:0039019)
5.0 29.8 GO:0008228 opsonization(GO:0008228)
4.9 14.8 GO:0002488 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
4.9 48.7 GO:0032782 bile acid secretion(GO:0032782)
4.8 19.3 GO:0030221 basophil differentiation(GO:0030221)
4.8 9.5 GO:0044107 cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
4.7 18.9 GO:0006545 glycine biosynthetic process(GO:0006545)
4.7 18.7 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
4.7 18.6 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
4.6 13.7 GO:0006116 NADH oxidation(GO:0006116)
4.6 13.7 GO:0061744 motor behavior(GO:0061744)
4.5 49.9 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
4.5 13.6 GO:0002399 MHC class II protein complex assembly(GO:0002399) peptide antigen assembly with MHC class II protein complex(GO:0002503)
4.5 27.1 GO:0009812 flavonoid metabolic process(GO:0009812)
4.5 13.4 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
4.4 13.3 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
4.4 17.5 GO:0001834 trophectodermal cell proliferation(GO:0001834)
4.3 21.7 GO:1904717 regulation of AMPA glutamate receptor clustering(GO:1904717)
4.3 56.3 GO:0006702 androgen biosynthetic process(GO:0006702)
4.3 77.8 GO:0019373 epoxygenase P450 pathway(GO:0019373)
4.3 8.6 GO:0046967 cytosol to ER transport(GO:0046967) peptide antigen transport(GO:0046968)
4.2 12.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
4.2 8.4 GO:0070055 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
4.2 16.8 GO:0034201 response to oleic acid(GO:0034201)
4.2 8.4 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
4.2 25.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
4.1 16.5 GO:0046351 disaccharide biosynthetic process(GO:0046351)
4.1 8.2 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) regulation of interleukin-6-mediated signaling pathway(GO:0070103)
4.1 16.2 GO:2000195 negative regulation of female gonad development(GO:2000195)
4.0 121.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
4.0 20.2 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
4.0 19.9 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
3.9 7.8 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
3.9 15.6 GO:0061017 hepatoblast differentiation(GO:0061017)
3.9 50.8 GO:0042730 fibrinolysis(GO:0042730)
3.9 46.7 GO:0042359 vitamin D metabolic process(GO:0042359)
3.9 15.5 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
3.8 7.7 GO:0001805 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805) peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
3.8 26.9 GO:0007144 female meiosis I(GO:0007144)
3.8 7.5 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463)
3.8 11.3 GO:1990009 retinal cell apoptotic process(GO:1990009)
3.8 11.3 GO:0002215 defense response to nematode(GO:0002215)
3.7 18.6 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
3.7 11.1 GO:0006642 triglyceride mobilization(GO:0006642)
3.7 22.3 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
3.7 33.4 GO:0045759 negative regulation of action potential(GO:0045759)
3.7 7.4 GO:0042531 regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
3.7 11.0 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
3.7 54.9 GO:0015671 oxygen transport(GO:0015671)
3.7 11.0 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
3.6 7.3 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
3.6 10.9 GO:1900368 regulation of RNA interference(GO:1900368)
3.6 10.9 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
3.6 10.9 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
3.6 7.2 GO:0097052 L-kynurenine metabolic process(GO:0097052)
3.6 7.2 GO:0006548 histidine catabolic process(GO:0006548)
3.5 7.1 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
3.5 6.9 GO:0060460 left lung morphogenesis(GO:0060460)
3.4 10.3 GO:0046127 thymidine catabolic process(GO:0006214) pyrimidine deoxyribonucleoside catabolic process(GO:0046127)
3.4 65.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
3.4 17.0 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
3.4 10.1 GO:1902103 metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
3.4 10.1 GO:0046865 isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
3.4 10.1 GO:0060764 cell-cell signaling involved in mammary gland development(GO:0060764)
3.3 10.0 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) N-acetylneuraminate biosynthetic process(GO:0046380)
3.3 76.4 GO:0006855 drug transmembrane transport(GO:0006855)
3.3 3.3 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
3.3 13.2 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
3.3 6.6 GO:0006532 aspartate biosynthetic process(GO:0006532)
3.3 42.7 GO:0001542 ovulation from ovarian follicle(GO:0001542)
3.3 9.8 GO:0043605 cellular amide catabolic process(GO:0043605)
3.3 9.8 GO:0010813 neuropeptide catabolic process(GO:0010813)
3.3 29.4 GO:0034312 diol biosynthetic process(GO:0034312)
3.3 13.1 GO:0046061 dATP catabolic process(GO:0046061)
3.2 3.2 GO:0010266 response to vitamin B1(GO:0010266)
3.2 12.8 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
3.2 9.6 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
3.2 6.4 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
3.2 9.5 GO:0019303 D-ribose catabolic process(GO:0019303)
3.2 44.5 GO:0051764 actin crosslink formation(GO:0051764)
3.2 3.2 GO:1901073 glucosamine-containing compound biosynthetic process(GO:1901073)
3.1 9.4 GO:0021524 visceral motor neuron differentiation(GO:0021524) pulmonary vein morphogenesis(GO:0060577)
3.1 15.6 GO:0006741 NADP biosynthetic process(GO:0006741)
3.1 12.5 GO:0035963 cellular response to interleukin-13(GO:0035963)
3.1 9.3 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
3.1 12.4 GO:0070339 response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
3.1 12.3 GO:1990478 response to ultrasound(GO:1990478)
3.1 9.2 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
3.1 12.3 GO:0002281 macrophage activation involved in immune response(GO:0002281)
3.1 15.3 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
3.0 9.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
3.0 9.1 GO:0030210 heparin biosynthetic process(GO:0030210)
3.0 24.1 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
3.0 9.0 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
3.0 12.0 GO:0019230 proprioception(GO:0019230)
3.0 12.0 GO:0072107 regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107)
3.0 8.9 GO:0045575 basophil activation(GO:0045575)
3.0 8.9 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
2.9 8.8 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
2.9 20.5 GO:0055089 fatty acid homeostasis(GO:0055089)
2.9 14.6 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
2.9 14.4 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
2.9 2.9 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
2.9 2.9 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
2.9 17.2 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
2.9 20.0 GO:0042159 lipoprotein catabolic process(GO:0042159)
2.9 14.3 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
2.9 14.3 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
2.8 8.5 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
2.8 56.1 GO:0030574 collagen catabolic process(GO:0030574)
2.8 2.8 GO:0003162 atrioventricular node development(GO:0003162)
2.8 5.6 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
2.8 16.7 GO:0006287 base-excision repair, gap-filling(GO:0006287)
2.8 13.8 GO:0030070 insulin processing(GO:0030070)
2.8 82.5 GO:0019369 arachidonic acid metabolic process(GO:0019369)
2.7 5.5 GO:0006145 purine nucleobase catabolic process(GO:0006145)
2.7 10.9 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
2.7 8.2 GO:1902463 protein localization to cell leading edge(GO:1902463)
2.7 18.8 GO:0006477 protein sulfation(GO:0006477)
2.7 13.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
2.7 8.0 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
2.7 8.0 GO:0006059 hexitol metabolic process(GO:0006059)
2.7 5.3 GO:0071830 positive regulation of lipoprotein particle clearance(GO:0010986) chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
2.6 21.1 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
2.6 5.2 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
2.6 18.1 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)
2.6 7.7 GO:0021874 Wnt signaling pathway involved in forebrain neuroblast division(GO:0021874)
2.6 7.7 GO:0071283 cellular response to iron(III) ion(GO:0071283)
2.6 35.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
2.5 2.5 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
2.5 7.6 GO:0035964 COPI-coated vesicle budding(GO:0035964)
2.5 7.6 GO:0060545 positive regulation of necroptotic process(GO:0060545)
2.5 7.6 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
2.5 15.2 GO:0006572 tyrosine catabolic process(GO:0006572)
2.5 10.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
2.5 5.0 GO:0043366 beta selection(GO:0043366)
2.5 47.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
2.5 2.5 GO:0010877 lipid transport involved in lipid storage(GO:0010877)
2.5 2.5 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
2.5 2.5 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909)
2.5 7.5 GO:0060166 olfactory pit development(GO:0060166)
2.5 7.5 GO:0097327 response to antineoplastic agent(GO:0097327)
2.5 7.5 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
2.5 7.5 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
2.5 9.9 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
2.5 7.4 GO:0042126 nitrate metabolic process(GO:0042126)
2.5 4.9 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
2.4 44.1 GO:0048305 immunoglobulin secretion(GO:0048305)
2.4 17.1 GO:0060700 regulation of ribonuclease activity(GO:0060700)
2.4 2.4 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
2.4 7.3 GO:0006529 asparagine biosynthetic process(GO:0006529)
2.4 7.3 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
2.4 2.4 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
2.4 38.6 GO:0033327 Leydig cell differentiation(GO:0033327)
2.4 4.8 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
2.4 28.9 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
2.4 9.6 GO:0060336 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
2.4 14.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
2.4 16.7 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
2.4 9.5 GO:0002337 B-1a B cell differentiation(GO:0002337)
2.4 11.8 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
2.4 7.1 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
2.3 2.3 GO:0046671 negative regulation of retinal cell programmed cell death(GO:0046671)
2.3 7.0 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
2.3 9.4 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
2.3 9.4 GO:0034240 negative regulation of macrophage fusion(GO:0034240)
2.3 7.0 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
2.3 9.3 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
2.3 11.6 GO:0000255 allantoin metabolic process(GO:0000255)
2.3 20.7 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
2.3 27.4 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
2.3 6.8 GO:1901227 negative regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901227)
2.3 18.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
2.3 9.0 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
2.2 11.2 GO:0008295 spermidine biosynthetic process(GO:0008295)
2.2 11.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
2.2 13.4 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
2.2 76.1 GO:0035456 response to interferon-beta(GO:0035456)
2.2 13.4 GO:0006537 glutamate biosynthetic process(GO:0006537)
2.2 26.7 GO:0006968 cellular defense response(GO:0006968)
2.2 6.7 GO:0035622 intrahepatic bile duct development(GO:0035622)
2.2 8.8 GO:0046645 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
2.2 6.6 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
2.2 6.5 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
2.2 15.1 GO:0001787 natural killer cell proliferation(GO:0001787)
2.1 64.3 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
2.1 12.8 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
2.1 6.4 GO:1902963 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
2.1 8.5 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
2.1 21.3 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
2.1 8.5 GO:0021526 medial motor column neuron differentiation(GO:0021526)
2.1 12.7 GO:1990928 response to amino acid starvation(GO:1990928)
2.1 8.4 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
2.1 6.3 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
2.1 6.3 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
2.1 4.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
2.1 20.6 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
2.1 20.6 GO:0070365 hepatocyte differentiation(GO:0070365)
2.0 4.1 GO:0006004 fucose metabolic process(GO:0006004)
2.0 16.3 GO:0015886 heme transport(GO:0015886)
2.0 2.0 GO:0034351 negative regulation of glial cell apoptotic process(GO:0034351)
2.0 8.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
2.0 18.2 GO:0010572 positive regulation of platelet activation(GO:0010572)
2.0 14.2 GO:0019388 galactose catabolic process(GO:0019388)
2.0 14.2 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
2.0 10.1 GO:0042448 progesterone metabolic process(GO:0042448)
2.0 6.1 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
2.0 4.0 GO:0044375 regulation of peroxisome size(GO:0044375)
2.0 5.9 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
2.0 4.0 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
2.0 5.9 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
2.0 17.8 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
2.0 5.9 GO:2000382 positive regulation of mesoderm development(GO:2000382)
2.0 7.9 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
2.0 21.5 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
2.0 78.2 GO:0001523 retinoid metabolic process(GO:0001523)
1.9 11.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
1.9 7.8 GO:0072086 specification of loop of Henle identity(GO:0072086)
1.9 5.8 GO:0006528 asparagine metabolic process(GO:0006528)
1.9 5.8 GO:0002933 lipid hydroxylation(GO:0002933)
1.9 21.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
1.9 5.8 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
1.9 3.8 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455)
1.9 15.2 GO:0006691 leukotriene metabolic process(GO:0006691)
1.9 3.8 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
1.9 5.6 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
1.9 16.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
1.9 14.8 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
1.8 22.1 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
1.8 1.8 GO:0046337 phosphatidylethanolamine metabolic process(GO:0046337)
1.8 12.8 GO:0042228 interleukin-8 biosynthetic process(GO:0042228)
1.8 5.5 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
1.8 1.8 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
1.8 9.0 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
1.8 10.8 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
1.8 3.6 GO:0061056 sclerotome development(GO:0061056)
1.8 7.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
1.8 1.8 GO:0034971 histone H3-R17 methylation(GO:0034971)
1.8 7.1 GO:0071500 cellular response to nitrosative stress(GO:0071500)
1.8 12.4 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
1.8 3.5 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
1.8 7.0 GO:0001579 medium-chain fatty acid transport(GO:0001579)
1.8 22.8 GO:0006783 heme biosynthetic process(GO:0006783)
1.8 10.5 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
1.8 5.3 GO:0050755 chemokine metabolic process(GO:0050755)
1.7 10.5 GO:0006068 ethanol catabolic process(GO:0006068)
1.7 3.5 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
1.7 6.9 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
1.7 5.1 GO:1904976 cellular response to bleomycin(GO:1904976)
1.7 8.5 GO:0001922 B-1 B cell homeostasis(GO:0001922)
1.7 5.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.7 23.6 GO:1903140 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
1.7 10.1 GO:0010193 response to ozone(GO:0010193)
1.7 3.4 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
1.7 3.3 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
1.7 5.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.7 6.7 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
1.7 10.0 GO:0015677 copper ion import(GO:0015677)
1.6 4.9 GO:0023021 termination of signal transduction(GO:0023021)
1.6 3.2 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
1.6 6.4 GO:0051132 NK T cell activation(GO:0051132)
1.6 20.8 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
1.6 4.8 GO:1904747 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747) positive regulation of macrophage apoptotic process(GO:2000111)
1.6 14.3 GO:0002934 desmosome organization(GO:0002934)
1.6 1.6 GO:1901656 glycoside transport(GO:1901656)
1.6 4.7 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
1.6 9.4 GO:0070269 pyroptosis(GO:0070269)
1.6 4.7 GO:0032916 positive regulation of transforming growth factor beta3 production(GO:0032916)
1.6 15.6 GO:0048368 lateral mesoderm development(GO:0048368)
1.6 4.7 GO:2000360 regulation of binding of sperm to zona pellucida(GO:2000359) negative regulation of binding of sperm to zona pellucida(GO:2000360)
1.6 4.7 GO:0015680 intracellular copper ion transport(GO:0015680)
1.5 4.6 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
1.5 1.5 GO:0038027 apolipoprotein A-I-mediated signaling pathway(GO:0038027)
1.5 4.6 GO:0071934 thiamine transmembrane transport(GO:0071934)
1.5 3.1 GO:0001545 primary ovarian follicle growth(GO:0001545)
1.5 4.6 GO:0021698 cerebellar cortex structural organization(GO:0021698)
1.5 6.1 GO:0043587 tongue morphogenesis(GO:0043587)
1.5 6.1 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
1.5 4.6 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
1.5 4.6 GO:0044704 mating plug formation(GO:0042628) single-organism reproductive behavior(GO:0044704) post-mating behavior(GO:0045297)
1.5 12.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
1.5 3.0 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
1.5 9.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
1.5 7.5 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
1.5 10.5 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
1.5 11.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.5 7.4 GO:0021747 cochlear nucleus development(GO:0021747)
1.5 4.5 GO:0071464 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) cellular response to hydrostatic pressure(GO:0071464)
1.5 7.4 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133)
1.5 3.0 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
1.5 5.9 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
1.5 17.6 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
1.5 1.5 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
1.5 13.1 GO:0002467 germinal center formation(GO:0002467)
1.4 4.3 GO:0032474 otolith morphogenesis(GO:0032474)
1.4 18.4 GO:0033344 cholesterol efflux(GO:0033344)
1.4 2.8 GO:0071298 cellular response to L-ascorbic acid(GO:0071298)
1.4 5.6 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
1.4 9.8 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
1.4 5.6 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
1.4 9.8 GO:0001774 microglial cell activation(GO:0001774)
1.4 4.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
1.4 4.2 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
1.4 2.8 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
1.4 5.6 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
1.4 16.7 GO:0044320 cellular response to leptin stimulus(GO:0044320)
1.4 16.7 GO:0034501 protein localization to kinetochore(GO:0034501)
1.4 9.7 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
1.4 9.5 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
1.4 4.1 GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
1.4 4.1 GO:0042412 taurine biosynthetic process(GO:0042412)
1.4 38.0 GO:0043171 peptide catabolic process(GO:0043171)
1.4 24.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
1.3 6.7 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
1.3 4.0 GO:0071373 cellular response to luteinizing hormone stimulus(GO:0071373)
1.3 18.8 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
1.3 4.0 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
1.3 2.7 GO:0019087 transformation of host cell by virus(GO:0019087)
1.3 6.7 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
1.3 4.0 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
1.3 13.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
1.3 1.3 GO:0002339 B cell selection(GO:0002339)
1.3 10.6 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
1.3 4.0 GO:0010133 proline catabolic process to glutamate(GO:0010133)
1.3 2.7 GO:0043650 dicarboxylic acid biosynthetic process(GO:0043650)
1.3 3.9 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
1.3 2.6 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
1.3 2.6 GO:0043134 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
1.3 13.0 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
1.3 7.8 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
1.3 3.9 GO:0045054 constitutive secretory pathway(GO:0045054)
1.3 7.7 GO:0060033 anatomical structure regression(GO:0060033)
1.3 3.9 GO:0071461 cellular response to redox state(GO:0071461)
1.3 3.9 GO:0006011 UDP-glucose metabolic process(GO:0006011)
1.3 9.0 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
1.3 8.9 GO:0019395 fatty acid oxidation(GO:0019395)
1.3 7.6 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
1.3 3.8 GO:1903918 detection of muscle stretch(GO:0035995) regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919)
1.3 5.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
1.3 2.5 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
1.3 6.3 GO:0038161 prolactin signaling pathway(GO:0038161)
1.3 8.8 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
1.3 6.3 GO:1904401 response to Thyroid stimulating hormone(GO:1904400) cellular response to Thyroid stimulating hormone(GO:1904401)
1.3 10.0 GO:0045059 positive thymic T cell selection(GO:0045059)
1.3 2.5 GO:0006567 threonine catabolic process(GO:0006567)
1.2 8.7 GO:2000018 regulation of male gonad development(GO:2000018)
1.2 6.2 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
1.2 5.0 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
1.2 85.7 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
1.2 2.5 GO:0042851 L-alanine metabolic process(GO:0042851)
1.2 4.9 GO:0071279 cellular response to cobalt ion(GO:0071279)
1.2 24.4 GO:0043277 apoptotic cell clearance(GO:0043277)
1.2 9.8 GO:0036017 response to erythropoietin(GO:0036017) cellular response to erythropoietin(GO:0036018)
1.2 10.9 GO:0006689 ganglioside catabolic process(GO:0006689)
1.2 12.1 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
1.2 14.5 GO:0097284 hepatocyte apoptotic process(GO:0097284)
1.2 4.8 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
1.2 2.4 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
1.2 3.6 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
1.2 9.6 GO:0033004 negative regulation of mast cell activation(GO:0033004)
1.2 12.0 GO:0019359 nicotinamide nucleotide biosynthetic process(GO:0019359) pyridine nucleotide biosynthetic process(GO:0019363)
1.2 6.0 GO:0060482 lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482)
1.2 2.3 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
1.2 7.0 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
1.2 9.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
1.2 12.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
1.2 3.5 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
1.2 3.5 GO:0030223 neutrophil differentiation(GO:0030223)
1.1 5.7 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
1.1 4.6 GO:1903334 positive regulation of protein folding(GO:1903334)
1.1 6.9 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
1.1 4.6 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
1.1 13.6 GO:0036065 fucosylation(GO:0036065)
1.1 4.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
1.1 1.1 GO:0009946 proximal/distal axis specification(GO:0009946) specification of axis polarity(GO:0065001)
1.1 4.5 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
1.1 3.4 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
1.1 71.3 GO:0055088 lipid homeostasis(GO:0055088)
1.1 3.4 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
1.1 12.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
1.1 2.2 GO:0006407 rRNA export from nucleus(GO:0006407)
1.1 3.3 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
1.1 1.1 GO:2000449 CD8-positive, alpha-beta T cell extravasation(GO:0035697) regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
1.1 44.3 GO:0030193 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
1.1 5.5 GO:1903278 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
1.1 4.4 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
1.1 9.8 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
1.1 43.4 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
1.1 2.2 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
1.1 51.8 GO:0032094 response to food(GO:0032094)
1.1 17.2 GO:0001887 selenium compound metabolic process(GO:0001887)
1.1 5.4 GO:0010040 response to iron(II) ion(GO:0010040)
1.1 3.2 GO:0006713 glucocorticoid catabolic process(GO:0006713)
1.1 3.2 GO:0030449 regulation of complement activation(GO:0030449)
1.1 4.3 GO:0032647 regulation of interferon-alpha production(GO:0032647)
1.1 1.1 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
1.1 4.2 GO:0045779 negative regulation of bone resorption(GO:0045779)
1.1 3.2 GO:1901726 negative regulation of histone deacetylase activity(GO:1901726)
1.1 13.7 GO:0030225 macrophage differentiation(GO:0030225)
1.0 4.2 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
1.0 7.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
1.0 8.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
1.0 18.8 GO:0006805 xenobiotic metabolic process(GO:0006805)
1.0 14.4 GO:1902571 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
1.0 9.3 GO:0010668 ectodermal cell differentiation(GO:0010668)
1.0 2.1 GO:0060431 foregut regionalization(GO:0060423) lung field specification(GO:0060424) primary lung bud formation(GO:0060431) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047) Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953) canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
1.0 4.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211) vascular wound healing(GO:0061042)
1.0 2.0 GO:1904798 positive regulation of core promoter binding(GO:1904798)
1.0 2.0 GO:0009751 response to salicylic acid(GO:0009751)
1.0 11.2 GO:0048246 macrophage chemotaxis(GO:0048246)
1.0 9.0 GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
1.0 5.9 GO:0042832 defense response to protozoan(GO:0042832)
1.0 2.0 GO:0070384 Harderian gland development(GO:0070384)
1.0 23.8 GO:0009303 rRNA transcription(GO:0009303)
1.0 2.0 GO:0048749 compound eye development(GO:0048749)
1.0 2.0 GO:0032264 IMP salvage(GO:0032264)
1.0 3.0 GO:1904395 positive regulation of receptor clustering(GO:1903911) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
1.0 17.7 GO:0048240 sperm capacitation(GO:0048240)
1.0 9.7 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
1.0 1.9 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
1.0 3.8 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
1.0 5.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.9 1.9 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.9 2.8 GO:0043368 positive T cell selection(GO:0043368)
0.9 9.3 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
0.9 12.1 GO:0019835 cytolysis(GO:0019835)
0.9 10.2 GO:0002360 T cell lineage commitment(GO:0002360)
0.9 5.5 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.9 1.8 GO:0038086 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.9 7.2 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.9 11.7 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.9 2.7 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) protein localization to vacuolar membrane(GO:1903778)
0.9 3.6 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.9 6.2 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.9 2.7 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.9 1.8 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.9 7.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.9 3.5 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737) mammary gland branching involved in pregnancy(GO:0060745) baculum development(GO:1990375)
0.9 4.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.9 1.8 GO:0018963 phthalate metabolic process(GO:0018963)
0.9 35.0 GO:1902652 cholesterol metabolic process(GO:0008203) secondary alcohol metabolic process(GO:1902652)
0.9 4.3 GO:0070995 NADPH oxidation(GO:0070995)
0.9 4.3 GO:0007341 penetration of zona pellucida(GO:0007341)
0.9 6.9 GO:0050856 regulation of T cell receptor signaling pathway(GO:0050856)
0.9 1.7 GO:0060290 transdifferentiation(GO:0060290)
0.9 7.7 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.9 1.7 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.9 2.6 GO:0051684 maintenance of Golgi location(GO:0051684)
0.9 2.6 GO:0050820 positive regulation of coagulation(GO:0050820)
0.8 2.5 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.8 3.4 GO:0070827 chromatin maintenance(GO:0070827)
0.8 0.8 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.8 4.2 GO:0097006 regulation of plasma lipoprotein particle levels(GO:0097006)
0.8 4.2 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.8 2.5 GO:0009758 carbohydrate utilization(GO:0009758)
0.8 1.7 GO:0034368 macromolecular complex remodeling(GO:0034367) protein-lipid complex remodeling(GO:0034368) plasma lipoprotein particle remodeling(GO:0034369)
0.8 5.8 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.8 3.3 GO:0022417 protein maturation by protein folding(GO:0022417)
0.8 10.0 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.8 6.6 GO:0046415 urate metabolic process(GO:0046415)
0.8 3.3 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.8 38.8 GO:0009062 fatty acid catabolic process(GO:0009062)
0.8 2.4 GO:0090232 positive regulation of spindle checkpoint(GO:0090232) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.8 3.2 GO:0048570 notochord morphogenesis(GO:0048570)
0.8 4.0 GO:0006177 GMP biosynthetic process(GO:0006177)
0.8 5.6 GO:1901563 cellular response to camptothecin(GO:0072757) response to camptothecin(GO:1901563)
0.8 3.2 GO:1904044 response to aldosterone(GO:1904044)
0.8 142.6 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.8 4.0 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384)
0.8 27.6 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.8 2.4 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.8 4.7 GO:0006983 ER overload response(GO:0006983)
0.8 7.8 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.8 2.3 GO:0001562 response to protozoan(GO:0001562)
0.8 3.1 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.8 6.9 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.8 3.1 GO:0044691 tooth eruption(GO:0044691)
0.8 2.3 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.8 27.4 GO:0071346 cellular response to interferon-gamma(GO:0071346)
0.8 6.8 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.8 2.3 GO:0036297 interstrand cross-link repair(GO:0036297)
0.8 21.2 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.8 12.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.8 1.5 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.8 4.5 GO:0042420 dopamine catabolic process(GO:0042420)
0.7 13.4 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.7 7.5 GO:0008206 bile acid metabolic process(GO:0008206)
0.7 2.2 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
0.7 4.4 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.7 2.9 GO:0060178 regulation of exocyst localization(GO:0060178)
0.7 3.6 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.7 1.5 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.7 2.9 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.7 0.7 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.7 9.4 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.7 7.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.7 20.0 GO:0030199 collagen fibril organization(GO:0030199)
0.7 21.4 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.7 5.6 GO:2000194 regulation of female gonad development(GO:2000194)
0.7 8.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.7 4.9 GO:2001028 positive regulation of endothelial cell chemotaxis(GO:2001028)
0.7 3.4 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.7 10.3 GO:0000303 response to superoxide(GO:0000303)
0.7 2.0 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.7 0.7 GO:0048696 regulation of collateral sprouting in absence of injury(GO:0048696)
0.7 1.4 GO:0070375 ERK5 cascade(GO:0070375)
0.7 8.0 GO:0015816 glycine transport(GO:0015816)
0.7 2.7 GO:0051660 establishment of centrosome localization(GO:0051660)
0.7 3.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.7 2.6 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.7 4.0 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.7 3.3 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.7 3.3 GO:0071316 cellular response to nicotine(GO:0071316)
0.7 9.2 GO:0001556 oocyte maturation(GO:0001556)
0.7 6.6 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498) S-adenosylmethionine metabolic process(GO:0046500)
0.7 3.3 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.7 16.3 GO:0032527 protein exit from endoplasmic reticulum(GO:0032527)
0.6 1.3 GO:0034239 regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.6 2.6 GO:0032919 spermine acetylation(GO:0032919)
0.6 1.3 GO:0035106 operant conditioning(GO:0035106)
0.6 5.0 GO:2000811 negative regulation of anoikis(GO:2000811)
0.6 2.5 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.6 1.9 GO:0046223 toxin catabolic process(GO:0009407) mycotoxin metabolic process(GO:0043385) mycotoxin catabolic process(GO:0043387) aflatoxin metabolic process(GO:0046222) aflatoxin catabolic process(GO:0046223) secondary metabolite catabolic process(GO:0090487) organic heteropentacyclic compound metabolic process(GO:1901376) organic heteropentacyclic compound catabolic process(GO:1901377)
0.6 3.1 GO:0061085 regulation of histone H3-K27 methylation(GO:0061085) positive regulation of histone H3-K27 methylation(GO:0061087)
0.6 4.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.6 17.3 GO:0035036 sperm-egg recognition(GO:0035036)
0.6 4.9 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.6 4.9 GO:0018377 protein myristoylation(GO:0018377)
0.6 11.5 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.6 5.4 GO:0001782 B cell homeostasis(GO:0001782)
0.6 2.4 GO:0045792 negative regulation of cell size(GO:0045792)
0.6 6.6 GO:0001945 lymph vessel development(GO:0001945)
0.6 2.4 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.6 0.6 GO:0042346 positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.6 1.8 GO:0060155 platelet dense granule organization(GO:0060155)
0.6 2.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.6 1.2 GO:0080144 amino acid homeostasis(GO:0080144)
0.6 5.3 GO:0072520 seminiferous tubule development(GO:0072520)
0.6 1.8 GO:0030920 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.6 2.9 GO:0019405 alditol catabolic process(GO:0019405)
0.6 4.0 GO:0009650 UV protection(GO:0009650)
0.6 2.8 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.6 1.7 GO:2001212 regulation of vasculogenesis(GO:2001212)
0.6 2.3 GO:0072014 proximal tubule development(GO:0072014)
0.6 4.0 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.6 5.1 GO:1990403 embryonic brain development(GO:1990403)
0.6 3.9 GO:0043686 co-translational protein modification(GO:0043686)
0.6 24.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.6 3.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.5 1.6 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.5 9.2 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.5 3.8 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.5 5.9 GO:0034063 stress granule assembly(GO:0034063)
0.5 2.7 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.5 8.1 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.5 4.3 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.5 3.2 GO:0014022 neural plate morphogenesis(GO:0001839) neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) convergent extension involved in organogenesis(GO:0060029)
0.5 5.8 GO:0002283 neutrophil activation involved in immune response(GO:0002283)
0.5 1.0 GO:0060440 trachea formation(GO:0060440) regulation of Golgi inheritance(GO:0090170)
0.5 3.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.5 13.7 GO:0032570 response to progesterone(GO:0032570)
0.5 2.5 GO:0006311 meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
0.5 1.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.5 2.5 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.5 2.0 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.5 5.4 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.5 2.4 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.5 5.8 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.5 1.0 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.5 3.3 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904) ether lipid metabolic process(GO:0046485)
0.5 1.0 GO:2000124 endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.5 2.4 GO:0035811 negative regulation of urine volume(GO:0035811)
0.5 5.6 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.5 3.7 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.5 41.1 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.5 0.9 GO:1901318 negative regulation of sperm motility(GO:1901318)
0.5 3.3 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.5 1.8 GO:0080154 regulation of fertilization(GO:0080154)
0.5 2.7 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.5 0.9 GO:0035425 autocrine signaling(GO:0035425)
0.4 32.3 GO:0042742 defense response to bacterium(GO:0042742)
0.4 4.0 GO:0001659 temperature homeostasis(GO:0001659)
0.4 4.9 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.4 5.3 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.4 2.6 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.4 4.8 GO:0035855 megakaryocyte development(GO:0035855)
0.4 4.8 GO:0060039 pericardium development(GO:0060039)
0.4 3.1 GO:0000726 non-recombinational repair(GO:0000726)
0.4 3.0 GO:0000012 single strand break repair(GO:0000012)
0.4 0.8 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.4 1.7 GO:0034227 tRNA thio-modification(GO:0034227)
0.4 3.8 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.4 1.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.4 1.7 GO:1902606 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.4 1.2 GO:0006188 IMP biosynthetic process(GO:0006188) 'de novo' IMP biosynthetic process(GO:0006189)
0.4 3.3 GO:0002517 T cell tolerance induction(GO:0002517)
0.4 1.6 GO:0060005 vestibular reflex(GO:0060005)
0.4 0.8 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.4 2.8 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.4 1.6 GO:0044546 NLRP3 inflammasome complex assembly(GO:0044546) regulation of NLRP3 inflammasome complex assembly(GO:1900225)
0.4 0.8 GO:0040009 regulation of growth rate(GO:0040009)
0.4 1.6 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.4 0.8 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.4 3.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.4 3.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.4 2.7 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.4 0.8 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.4 5.4 GO:0033753 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.4 1.9 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.4 1.2 GO:0060023 soft palate development(GO:0060023)
0.4 5.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.4 1.1 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.4 10.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.4 4.9 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.4 1.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.4 14.2 GO:0050851 antigen receptor-mediated signaling pathway(GO:0050851)
0.4 1.1 GO:1901536 protection of DNA demethylation of female pronucleus(GO:0044726) regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.4 4.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.4 0.4 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.4 0.4 GO:0072104 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.4 1.8 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.4 1.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.4 7.2 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.4 1.4 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.4 1.1 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.3 4.2 GO:0006517 protein deglycosylation(GO:0006517)
0.3 1.7 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.3 1.7 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.3 1.0 GO:0019217 regulation of fatty acid metabolic process(GO:0019217)
0.3 1.0 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.3 1.3 GO:2000352 negative regulation of endothelial cell apoptotic process(GO:2000352)
0.3 11.8 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.3 2.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.3 0.6 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.3 3.8 GO:0046697 decidualization(GO:0046697)
0.3 3.8 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.3 2.8 GO:0034340 response to type I interferon(GO:0034340)
0.3 2.8 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.3 2.5 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.3 6.3 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.3 1.2 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.3 1.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.3 1.5 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.3 0.6 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.3 2.4 GO:0032986 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.3 1.5 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.3 1.8 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.3 2.1 GO:0034389 lipid particle organization(GO:0034389)
0.3 1.8 GO:0050915 sensory perception of sour taste(GO:0050915)
0.3 3.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.3 1.1 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.3 0.9 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.3 0.3 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.3 0.8 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.3 6.1 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.3 0.5 GO:0033578 protein glycosylation in Golgi(GO:0033578) regulation of protein glycosylation in Golgi(GO:0090283)
0.3 1.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.3 1.1 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.3 1.8 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.3 1.8 GO:0042559 pteridine-containing compound biosynthetic process(GO:0042559)
0.3 8.7 GO:0002088 lens development in camera-type eye(GO:0002088)
0.3 3.7 GO:0042130 negative regulation of T cell proliferation(GO:0042130)
0.3 1.0 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.2 2.0 GO:0046931 pore complex assembly(GO:0046931)
0.2 22.8 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
0.2 4.6 GO:0048536 spleen development(GO:0048536)
0.2 4.1 GO:0002067 glandular epithelial cell differentiation(GO:0002067)
0.2 3.1 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.2 0.7 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.2 0.2 GO:0070268 cornification(GO:0070268)
0.2 0.5 GO:0035815 positive regulation of renal sodium excretion(GO:0035815)
0.2 0.7 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.2 1.7 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 4.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.2 2.8 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.2 0.6 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.2 0.9 GO:0030035 microspike assembly(GO:0030035)
0.2 1.3 GO:0046519 sphingoid metabolic process(GO:0046519)
0.2 0.8 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.2 1.7 GO:0046549 retinal cone cell development(GO:0046549)
0.2 3.5 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.2 2.7 GO:0010165 response to X-ray(GO:0010165)
0.2 2.1 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.2 0.4 GO:1904948 midbrain dopaminergic neuron differentiation(GO:1904948)
0.2 2.0 GO:2000772 regulation of cellular senescence(GO:2000772)
0.2 1.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 2.3 GO:0042407 cristae formation(GO:0042407)
0.2 4.4 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.2 0.8 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.2 0.9 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.2 1.5 GO:1901889 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.2 1.8 GO:0032042 mitochondrial DNA metabolic process(GO:0032042)
0.2 1.4 GO:0002070 epithelial cell maturation(GO:0002070)
0.2 1.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.2 0.9 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.2 2.1 GO:0030261 chromosome condensation(GO:0030261)
0.2 1.4 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.2 2.1 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.2 0.5 GO:0044597 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.2 0.9 GO:0031297 replication fork processing(GO:0031297)
0.2 4.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2 0.7 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.2 1.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.2 0.3 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.2 1.3 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.2 2.1 GO:0006298 mismatch repair(GO:0006298)
0.2 1.0 GO:0009446 putrescine metabolic process(GO:0009445) putrescine biosynthetic process(GO:0009446) putrescine biosynthetic process from ornithine(GO:0033387)
0.2 0.6 GO:0034349 glial cell apoptotic process(GO:0034349)
0.2 1.2 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 0.4 GO:0010575 positive regulation of vascular endothelial growth factor production(GO:0010575)
0.1 0.4 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.1 1.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 5.1 GO:0009267 cellular response to starvation(GO:0009267)
0.1 2.0 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 0.4 GO:0030576 Cajal body organization(GO:0030576)
0.1 1.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 1.3 GO:0033622 integrin activation(GO:0033622)
0.1 0.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.9 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.1 GO:1904851 positive regulation of establishment of protein localization to telomere(GO:1904851)
0.1 1.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 2.5 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.5 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.1 1.0 GO:0002716 negative regulation of natural killer cell mediated immunity(GO:0002716)
0.1 0.7 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.8 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.5 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.9 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.1 0.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 3.0 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 1.7 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.1 3.1 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 1.3 GO:0048821 erythrocyte development(GO:0048821)
0.1 1.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.8 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.1 0.6 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.1 5.0 GO:0006401 RNA catabolic process(GO:0006401)
0.1 0.1 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.1 0.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 1.1 GO:0051567 histone H3-K9 methylation(GO:0051567)
0.1 0.4 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 0.5 GO:0010224 response to UV-B(GO:0010224)
0.1 0.2 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.7 GO:0036010 protein localization to endosome(GO:0036010)
0.1 0.2 GO:0006012 galactose metabolic process(GO:0006012)
0.1 1.2 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.2 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.7 GO:0032801 receptor catabolic process(GO:0032801)
0.1 2.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.4 GO:0032060 bleb assembly(GO:0032060)
0.1 0.3 GO:0072366 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.1 0.3 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.5 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 1.0 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.6 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.1 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.5 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.4 GO:0051307 meiotic chromosome separation(GO:0051307)
0.0 0.1 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.5 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.0 0.2 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.0 0.5 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.6 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.4 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 1.3 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.2 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 1.0 GO:0032006 regulation of TOR signaling(GO:0032006)
0.0 0.5 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 0.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.2 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.1 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.1 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
27.6 110.2 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
15.3 45.8 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
15.3 61.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
13.2 66.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
13.0 78.1 GO:0005579 membrane attack complex(GO:0005579)
11.9 167.0 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
10.4 41.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
10.1 1147.9 GO:0072562 blood microparticle(GO:0072562)
10.0 29.9 GO:0034362 low-density lipoprotein particle(GO:0034362)
9.2 46.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
7.8 23.4 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
7.3 29.4 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
6.4 19.3 GO:0046691 intracellular canaliculus(GO:0046691)
6.4 197.9 GO:0042588 zymogen granule(GO:0042588)
5.9 23.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
5.8 5.8 GO:0097169 AIM2 inflammasome complex(GO:0097169)
5.7 45.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
5.2 15.5 GO:0071149 TEAD-2-YAP complex(GO:0071149)
4.7 9.4 GO:0072557 IPAF inflammasome complex(GO:0072557)
4.6 27.9 GO:1990111 spermatoproteasome complex(GO:1990111)
4.4 8.9 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
4.4 43.9 GO:0045179 apical cortex(GO:0045179)
4.2 4.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
4.1 12.2 GO:0036488 CHOP-C/EBP complex(GO:0036488)
4.0 28.3 GO:0005833 hemoglobin complex(GO:0005833)
4.0 15.9 GO:0019814 immunoglobulin complex(GO:0019814)
3.6 10.8 GO:0032398 MHC class Ib protein complex(GO:0032398)
3.6 14.3 GO:0034774 secretory granule lumen(GO:0034774)
3.5 56.4 GO:0042613 MHC class II protein complex(GO:0042613)
3.5 13.8 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
3.4 3.4 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
3.4 6.9 GO:0031933 telomeric heterochromatin(GO:0031933)
3.4 44.3 GO:0046581 intercellular canaliculus(GO:0046581)
3.3 6.5 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
3.2 252.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
3.0 21.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
3.0 9.0 GO:0008537 proteasome activator complex(GO:0008537)
2.9 109.7 GO:0001772 immunological synapse(GO:0001772)
2.9 8.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
2.8 14.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
2.8 31.1 GO:0034364 plasma lipoprotein particle(GO:0034358) high-density lipoprotein particle(GO:0034364) lipoprotein particle(GO:1990777)
2.8 8.5 GO:0070557 PCNA-p21 complex(GO:0070557)
2.8 19.8 GO:0045293 mRNA editing complex(GO:0045293)
2.8 60.8 GO:0031528 microvillus membrane(GO:0031528)
2.6 7.9 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
2.6 13.1 GO:0097413 Lewy body(GO:0097413)
2.6 13.0 GO:0033093 Weibel-Palade body(GO:0033093)
2.6 7.7 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
2.5 7.6 GO:0070421 DNA ligase III-XRCC1 complex(GO:0070421)
2.4 4.9 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
2.4 12.1 GO:0070195 growth hormone receptor complex(GO:0070195)
2.3 14.1 GO:0042825 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
2.3 4.7 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
2.3 41.6 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
2.3 50.5 GO:0030057 desmosome(GO:0030057)
2.3 18.2 GO:0000796 condensin complex(GO:0000796)
2.3 11.3 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
2.1 14.9 GO:0031264 death-inducing signaling complex(GO:0031264)
2.1 8.4 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
2.1 6.3 GO:0043159 acrosomal matrix(GO:0043159)
2.1 28.9 GO:0044216 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
2.1 12.3 GO:0005796 Golgi lumen(GO:0005796)
2.0 146.5 GO:0045095 keratin filament(GO:0045095)
2.0 4.1 GO:0036398 TCR signalosome(GO:0036398)
2.0 15.8 GO:0000138 Golgi trans cisterna(GO:0000138)
1.9 27.2 GO:0030127 COPII vesicle coat(GO:0030127)
1.9 7.7 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
1.9 7.6 GO:0060053 neurofilament cytoskeleton(GO:0060053)
1.9 7.4 GO:0036156 inner dynein arm(GO:0036156)
1.8 40.6 GO:0042629 mast cell granule(GO:0042629)
1.8 5.5 GO:0005760 gamma DNA polymerase complex(GO:0005760)
1.8 31.0 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
1.8 5.4 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
1.8 7.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
1.8 7.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
1.7 20.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
1.7 15.2 GO:0043020 NADPH oxidase complex(GO:0043020)
1.7 16.7 GO:0005771 multivesicular body(GO:0005771)
1.6 8.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
1.6 6.6 GO:0000444 MIS12/MIND type complex(GO:0000444)
1.6 14.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
1.6 6.4 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
1.5 10.7 GO:0097524 sperm plasma membrane(GO:0097524)
1.5 12.2 GO:0070578 RISC-loading complex(GO:0070578)
1.5 13.4 GO:0005915 zonula adherens(GO:0005915)
1.5 4.5 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
1.5 5.9 GO:0035339 SPOTS complex(GO:0035339)
1.5 10.3 GO:0031415 NatA complex(GO:0031415)
1.5 5.9 GO:0043564 Ku70:Ku80 complex(GO:0043564)
1.4 5.7 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
1.4 2.9 GO:0043511 inhibin complex(GO:0043511)
1.4 2.7 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
1.3 16.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
1.3 9.0 GO:0030061 mitochondrial crista(GO:0030061)
1.3 5.1 GO:0005588 collagen type V trimer(GO:0005588)
1.3 6.3 GO:1903767 sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
1.3 7.6 GO:0030289 protein phosphatase 4 complex(GO:0030289)
1.3 16.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.2 6.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
1.2 4.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.2 9.5 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
1.2 10.7 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
1.2 4.7 GO:0097149 centralspindlin complex(GO:0097149)
1.2 3.5 GO:0044299 C-fiber(GO:0044299)
1.1 5.7 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
1.1 4.6 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
1.1 9.0 GO:0005614 interstitial matrix(GO:0005614)
1.1 5.6 GO:0045098 type III intermediate filament(GO:0045098)
1.1 7.8 GO:0001739 sex chromatin(GO:0001739)
1.1 12.1 GO:0031091 platelet alpha granule(GO:0031091)
1.1 7.6 GO:0044194 cytolytic granule(GO:0044194)
1.1 5.3 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
1.1 24.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
1.1 7.4 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
1.0 36.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
1.0 3.1 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
1.0 5.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
1.0 4.0 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
1.0 128.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
1.0 6.7 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.9 713.1 GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network(GO:0042175)
0.9 2.7 GO:0031085 BLOC-3 complex(GO:0031085)
0.9 3.6 GO:0061689 tricellular tight junction(GO:0061689)
0.9 14.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.9 2.7 GO:0005899 insulin receptor complex(GO:0005899)
0.9 2.7 GO:0044611 nuclear pore inner ring(GO:0044611)
0.9 5.3 GO:0036128 CatSper complex(GO:0036128)
0.9 16.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.9 11.4 GO:0097542 ciliary tip(GO:0097542)
0.9 45.2 GO:0005811 lipid particle(GO:0005811)
0.9 2.6 GO:0070765 gamma-secretase complex(GO:0070765)
0.8 8.5 GO:0044754 autolysosome(GO:0044754)
0.8 2.5 GO:0005960 glycine cleavage complex(GO:0005960)
0.8 2.5 GO:0042101 T cell receptor complex(GO:0042101)
0.8 7.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.8 3.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.8 81.9 GO:0016363 nuclear matrix(GO:0016363)
0.8 6.9 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.8 51.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.8 986.8 GO:0005615 extracellular space(GO:0005615)
0.8 3.0 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.7 17.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.7 8.0 GO:0008385 IkappaB kinase complex(GO:0008385)
0.7 33.3 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.7 2.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.7 147.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.7 2.8 GO:0071203 WASH complex(GO:0071203)
0.7 11.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.7 2.8 GO:1990909 Wnt signalosome(GO:1990909)
0.7 2.8 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.7 23.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.7 7.5 GO:0042611 MHC protein complex(GO:0042611)
0.7 11.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.7 5.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.6 6.4 GO:0031527 filopodium membrane(GO:0031527)
0.6 3.2 GO:0035061 interchromatin granule(GO:0035061)
0.6 13.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.6 26.6 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.6 1.8 GO:0002081 outer acrosomal membrane(GO:0002081)
0.6 22.0 GO:0060170 ciliary membrane(GO:0060170)
0.6 55.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.6 5.9 GO:0030663 COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.6 2.9 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.6 2.9 GO:0061617 MICOS complex(GO:0061617)
0.5 1.6 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
0.5 3.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.5 5.9 GO:0030914 STAGA complex(GO:0030914)
0.5 6.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.5 3.3 GO:0032300 mismatch repair complex(GO:0032300)
0.5 9.8 GO:0005685 U1 snRNP(GO:0005685)
0.4 2.2 GO:0034455 t-UTP complex(GO:0034455)
0.4 24.6 GO:0005840 ribosome(GO:0005840)
0.4 1.7 GO:0035363 histone locus body(GO:0035363)
0.4 6.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.4 2.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.4 38.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 4.9 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.4 3.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.4 3.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.4 6.6 GO:0033391 chromatoid body(GO:0033391)
0.4 2.3 GO:0070449 elongin complex(GO:0070449)
0.4 3.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.4 4.5 GO:0005845 mRNA cap binding complex(GO:0005845)
0.4 2.2 GO:0044613 nuclear pore central transport channel(GO:0044613) nuclear pore nuclear basket(GO:0044615)
0.4 1.4 GO:0072487 MSL complex(GO:0072487)
0.3 4.4 GO:0043196 varicosity(GO:0043196)
0.3 3.6 GO:0071564 npBAF complex(GO:0071564)
0.3 1.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.3 1.9 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.3 1.7 GO:0016461 unconventional myosin complex(GO:0016461)
0.3 1.7 GO:0005663 DNA replication factor C complex(GO:0005663)
0.3 1.1 GO:0030891 VCB complex(GO:0030891)
0.3 0.3 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.3 0.8 GO:0055087 Ski complex(GO:0055087)
0.3 1.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.3 3.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 1.1 GO:0005675 holo TFIIH complex(GO:0005675)
0.3 1.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.3 10.0 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.3 0.8 GO:0043203 axon hillock(GO:0043203)
0.3 59.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.3 1.5 GO:0000800 lateral element(GO:0000800)
0.2 2.5 GO:0071011 precatalytic spliceosome(GO:0071011)
0.2 8.0 GO:0016235 aggresome(GO:0016235)
0.2 3.0 GO:0005861 troponin complex(GO:0005861)
0.2 3.9 GO:0010369 chromocenter(GO:0010369)
0.2 4.2 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 0.9 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.2 2.1 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.2 0.8 GO:0071817 MMXD complex(GO:0071817)
0.2 1.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.2 0.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 1.1 GO:0016600 flotillin complex(GO:0016600)
0.2 1.9 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 2.0 GO:0031083 BLOC-1 complex(GO:0031083)
0.2 0.7 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 1.8 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 1.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 0.8 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.2 0.5 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.1 3.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.4 GO:0071004 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.1 5.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 2.1 GO:0030056 hemidesmosome(GO:0030056)
0.1 38.6 GO:0005667 transcription factor complex(GO:0005667)
0.1 0.3 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 7.5 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 1.9 GO:0000346 transcription export complex(GO:0000346)
0.1 0.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.6 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.8 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 2.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.7 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.1 GO:0030686 90S preribosome(GO:0030686)
0.1 1.6 GO:0000795 synaptonemal complex(GO:0000795)
0.1 1.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 1.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.2 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 9.4 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.0 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
32.4 97.1 GO:0031714 C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
25.2 75.6 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
23.5 70.4 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
21.0 63.1 GO:0004556 alpha-amylase activity(GO:0004556)
20.8 145.4 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
15.3 45.9 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
15.0 45.0 GO:0004911 interleukin-2 receptor activity(GO:0004911)
14.5 43.5 GO:0002060 purine nucleobase binding(GO:0002060)
13.9 41.6 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
13.5 67.3 GO:0019862 IgA binding(GO:0019862)
12.1 48.4 GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294)
11.6 57.9 GO:0005550 pheromone binding(GO:0005550)
11.5 46.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
10.8 32.3 GO:0031720 haptoglobin binding(GO:0031720)
10.4 83.5 GO:0070053 thrombospondin receptor activity(GO:0070053)
10.1 30.3 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
10.1 412.6 GO:0070330 aromatase activity(GO:0070330)
9.6 38.3 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
9.4 18.8 GO:0034186 apolipoprotein A-I binding(GO:0034186)
9.1 63.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
9.1 90.5 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
9.0 27.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
8.9 134.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
8.6 68.9 GO:0003996 acyl-CoA ligase activity(GO:0003996)
8.5 42.5 GO:0005499 vitamin D binding(GO:0005499)
8.5 34.0 GO:0008265 Mo-molybdopterin cofactor sulfurase activity(GO:0008265)
8.4 25.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
8.4 210.7 GO:0042288 MHC class I protein binding(GO:0042288)
8.2 40.8 GO:0043120 tumor necrosis factor binding(GO:0043120)
7.9 31.6 GO:0019960 C-X3-C chemokine binding(GO:0019960)
7.9 134.3 GO:0004806 triglyceride lipase activity(GO:0004806)
7.9 78.5 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
7.8 31.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
7.8 54.6 GO:0032052 bile acid binding(GO:0032052)
7.8 101.3 GO:1990405 protein antigen binding(GO:1990405)
7.7 161.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
7.6 30.6 GO:0047619 acylcarnitine hydrolase activity(GO:0047619)
7.6 37.9 GO:0019770 IgG receptor activity(GO:0019770)
7.6 37.8 GO:0001849 complement component C1q binding(GO:0001849)
7.4 111.3 GO:0017127 cholesterol transporter activity(GO:0017127)
7.4 89.0 GO:0001848 complement binding(GO:0001848)
7.3 51.2 GO:0035375 zymogen binding(GO:0035375)
7.2 36.1 GO:0016726 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
7.2 28.7 GO:0030492 hemoglobin binding(GO:0030492)
7.1 78.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
7.1 35.5 GO:0016841 ammonia-lyase activity(GO:0016841)
7.0 42.2 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
6.8 34.2 GO:0004103 choline kinase activity(GO:0004103)
6.7 208.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
6.7 33.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
6.7 33.3 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
6.6 19.7 GO:0004359 glutaminase activity(GO:0004359)
6.5 39.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
6.5 19.6 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
6.5 32.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
6.4 6.4 GO:0031686 A1 adenosine receptor binding(GO:0031686)
6.3 19.0 GO:0031893 vasopressin receptor binding(GO:0031893)
6.3 31.5 GO:0004301 epoxide hydrolase activity(GO:0004301)
6.3 37.8 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
6.2 242.2 GO:0004364 glutathione transferase activity(GO:0004364)
6.1 30.4 GO:0005534 galactose binding(GO:0005534)
6.1 24.3 GO:0034618 arginine binding(GO:0034618)
6.0 53.9 GO:0015232 heme transporter activity(GO:0015232)
5.9 29.6 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
5.9 23.6 GO:0004949 cannabinoid receptor activity(GO:0004949)
5.8 28.9 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
5.7 17.0 GO:0004522 ribonuclease A activity(GO:0004522)
5.7 22.7 GO:0048408 epidermal growth factor binding(GO:0048408)
5.6 16.9 GO:0008458 carnitine O-octanoyltransferase activity(GO:0008458) O-octanoyltransferase activity(GO:0016414)
5.5 631.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
5.5 16.5 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
5.5 38.3 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
5.4 5.4 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
5.3 42.6 GO:0008430 selenium binding(GO:0008430)
5.3 26.5 GO:0019763 immunoglobulin receptor activity(GO:0019763)
5.2 10.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
5.0 110.0 GO:0019825 oxygen binding(GO:0019825)
4.9 14.8 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
4.8 43.5 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
4.8 14.4 GO:0004040 amidase activity(GO:0004040)
4.7 14.2 GO:0070573 metallodipeptidase activity(GO:0070573)
4.7 9.3 GO:0055100 adiponectin binding(GO:0055100)
4.6 13.9 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
4.5 40.8 GO:0004859 phospholipase inhibitor activity(GO:0004859)
4.5 9.0 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
4.4 8.8 GO:0002114 interleukin-33 receptor activity(GO:0002114)
4.2 12.6 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
4.2 16.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
4.0 28.2 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
4.0 35.8 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
3.9 15.7 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
3.9 19.5 GO:0001155 TFIIIA-class transcription factor binding(GO:0001155)
3.9 15.6 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
3.8 11.5 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
3.8 72.6 GO:0008199 ferric iron binding(GO:0008199)
3.8 33.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
3.7 11.2 GO:0042296 ISG15 transferase activity(GO:0042296)
3.7 40.6 GO:0015245 fatty acid transporter activity(GO:0015245)
3.7 11.1 GO:0004793 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
3.7 51.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
3.6 35.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
3.6 14.3 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
3.6 7.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
3.5 14.2 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
3.5 10.5 GO:0019961 interferon binding(GO:0019961)
3.5 10.5 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
3.5 34.8 GO:0019957 C-C chemokine binding(GO:0019957)
3.5 10.4 GO:0070698 type I activin receptor binding(GO:0070698)
3.4 10.3 GO:0002054 nucleobase binding(GO:0002054)
3.4 10.3 GO:0004167 dopachrome isomerase activity(GO:0004167)
3.4 10.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
3.4 6.7 GO:0038100 nodal binding(GO:0038100)
3.4 10.1 GO:0070012 oligopeptidase activity(GO:0070012)
3.3 10.0 GO:0009384 N-acylmannosamine kinase activity(GO:0009384)
3.3 53.0 GO:0001972 retinoic acid binding(GO:0001972)
3.3 26.5 GO:0008172 S-methyltransferase activity(GO:0008172)
3.3 19.8 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
3.3 6.6 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
3.3 156.7 GO:0038024 cargo receptor activity(GO:0038024)
3.3 16.3 GO:0071723 lipopeptide binding(GO:0071723)
3.2 9.7 GO:0070404 NADH binding(GO:0070404)
3.2 19.3 GO:0050692 DBD domain binding(GO:0050692)
3.1 9.4 GO:0048030 disaccharide binding(GO:0048030)
3.1 37.3 GO:0004955 prostaglandin receptor activity(GO:0004955)
3.1 6.2 GO:0016803 ether hydrolase activity(GO:0016803)
3.1 12.3 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
3.0 27.4 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
3.0 27.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
3.0 9.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
3.0 3.0 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
3.0 30.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
3.0 57.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
3.0 11.8 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
3.0 17.7 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
2.9 11.6 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
2.9 23.1 GO:0051525 NFAT protein binding(GO:0051525)
2.9 37.2 GO:0035497 cAMP response element binding(GO:0035497)
2.8 17.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
2.8 17.0 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
2.8 5.6 GO:0050051 leukotriene-B4 20-monooxygenase activity(GO:0050051) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
2.8 8.3 GO:0019959 interleukin-8 binding(GO:0019959)
2.7 10.8 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
2.7 16.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
2.7 10.7 GO:0005136 interleukin-4 receptor binding(GO:0005136)
2.7 10.7 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
2.7 8.0 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
2.7 5.3 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
2.7 10.6 GO:0016833 oxo-acid-lyase activity(GO:0016833)
2.6 562.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
2.6 10.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
2.6 13.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
2.6 18.2 GO:0042608 T cell receptor binding(GO:0042608)
2.6 5.2 GO:0005131 growth hormone receptor binding(GO:0005131)
2.6 23.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
2.5 12.7 GO:0015252 hydrogen ion channel activity(GO:0015252)
2.5 20.3 GO:0042301 phosphate ion binding(GO:0042301)
2.5 12.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
2.5 2.5 GO:0016453 C-acetyltransferase activity(GO:0016453)
2.5 67.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
2.5 2.5 GO:0004954 prostanoid receptor activity(GO:0004954)
2.5 7.5 GO:0047522 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
2.5 7.4 GO:0035877 death effector domain binding(GO:0035877)
2.5 7.4 GO:0030151 molybdenum ion binding(GO:0030151)
2.5 9.8 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
2.5 9.8 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
2.4 7.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
2.4 7.3 GO:0050543 icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544)
2.4 16.9 GO:0001758 retinal dehydrogenase activity(GO:0001758)
2.4 7.2 GO:0042806 fucose binding(GO:0042806)
2.4 28.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
2.4 9.5 GO:0004903 growth hormone receptor activity(GO:0004903)
2.3 7.0 GO:0008506 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
2.3 14.0 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
2.3 9.3 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
2.3 7.0 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
2.3 4.7 GO:0032767 copper-dependent protein binding(GO:0032767)
2.3 11.6 GO:0046790 virion binding(GO:0046790)
2.3 13.8 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
2.3 6.8 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
2.3 9.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
2.3 34.2 GO:0045295 gamma-catenin binding(GO:0045295)
2.2 6.7 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
2.2 8.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
2.2 12.9 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
2.1 6.4 GO:0004925 prolactin receptor activity(GO:0004925)
2.1 8.6 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
2.1 12.8 GO:0016832 aldehyde-lyase activity(GO:0016832)
2.1 196.4 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
2.1 6.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
2.0 10.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
2.0 6.1 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
2.0 34.1 GO:0015238 drug transmembrane transporter activity(GO:0015238)
2.0 9.9 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
2.0 5.9 GO:0097677 STAT family protein binding(GO:0097677)
1.9 7.7 GO:0061665 SUMO ligase activity(GO:0061665)
1.9 7.6 GO:0004920 interleukin-10 receptor activity(GO:0004920)
1.9 13.3 GO:0051920 peroxiredoxin activity(GO:0051920)
1.9 17.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
1.9 254.8 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
1.9 46.9 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
1.9 13.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
1.9 7.5 GO:0019166 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
1.8 5.5 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
1.8 9.2 GO:0070324 thyroid hormone binding(GO:0070324)
1.8 5.4 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
1.8 14.5 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
1.8 26.9 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
1.8 21.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
1.8 89.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
1.8 5.3 GO:0016748 succinyltransferase activity(GO:0016748)
1.7 22.4 GO:0003796 lysozyme activity(GO:0003796)
1.7 31.0 GO:0023026 MHC class II protein complex binding(GO:0023026)
1.7 6.8 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
1.7 6.7 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
1.7 10.0 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
1.6 6.5 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
1.6 16.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
1.6 6.5 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
1.6 3.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
1.6 24.1 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
1.6 11.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
1.6 6.4 GO:0070051 fibrinogen binding(GO:0070051)
1.6 3.2 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
1.6 14.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
1.6 4.7 GO:0004046 aminoacylase activity(GO:0004046)
1.6 12.6 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
1.6 32.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
1.6 6.2 GO:0030172 troponin C binding(GO:0030172)
1.5 10.8 GO:0003896 DNA primase activity(GO:0003896)
1.5 17.0 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
1.5 6.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.5 7.5 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
1.5 27.0 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
1.5 5.9 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
1.5 24.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
1.5 32.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
1.5 5.8 GO:0004967 glucagon receptor activity(GO:0004967)
1.4 4.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
1.4 11.5 GO:0004630 phospholipase D activity(GO:0004630)
1.4 27.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
1.4 7.2 GO:0042289 MHC class II protein binding(GO:0042289)
1.4 14.3 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
1.4 4.3 GO:0031685 adenosine receptor binding(GO:0031685)
1.4 11.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
1.4 2.8 GO:0055102 lipase inhibitor activity(GO:0055102)
1.4 7.0 GO:0044547 DNA topoisomerase binding(GO:0044547)
1.4 11.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
1.4 40.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
1.4 5.4 GO:0002046 opsin binding(GO:0002046)
1.4 4.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
1.4 2.7 GO:0032190 acrosin binding(GO:0032190)
1.3 14.7 GO:0070402 NADPH binding(GO:0070402)
1.3 9.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
1.3 13.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
1.3 2.6 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
1.3 5.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
1.3 3.8 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
1.3 2.5 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
1.2 3.7 GO:0046979 TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
1.2 2.5 GO:0043559 insulin binding(GO:0043559)
1.2 6.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
1.2 2.4 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
1.2 4.8 GO:0019237 centromeric DNA binding(GO:0019237)
1.2 15.5 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
1.2 7.2 GO:0070728 leucine binding(GO:0070728)
1.2 5.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.2 9.4 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
1.2 9.3 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
1.2 10.5 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
1.2 29.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.2 5.8 GO:0010181 FMN binding(GO:0010181)
1.1 14.9 GO:0004601 peroxidase activity(GO:0004601)
1.1 4.5 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) palmitoyl-CoA 9-desaturase activity(GO:0032896)
1.1 3.4 GO:0004924 oncostatin-M receptor activity(GO:0004924)
1.1 8.9 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
1.1 4.4 GO:0070883 pre-miRNA binding(GO:0070883)
1.1 28.5 GO:0004016 adenylate cyclase activity(GO:0004016)
1.1 9.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.1 1.1 GO:0034584 piRNA binding(GO:0034584)
1.1 1.1 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634)
1.1 8.5 GO:0016004 phospholipase activator activity(GO:0016004)
1.1 3.2 GO:0030626 U12 snRNA binding(GO:0030626)
1.1 2.1 GO:0030984 kininogen binding(GO:0030984)
1.1 6.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
1.1 3.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
1.0 4.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
1.0 5.2 GO:1901612 cardiolipin binding(GO:1901612)
1.0 19.8 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
1.0 2.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
1.0 6.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
1.0 13.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.0 9.2 GO:0016208 AMP binding(GO:0016208)
1.0 9.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
1.0 12.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
1.0 32.7 GO:0005158 insulin receptor binding(GO:0005158)
1.0 4.0 GO:0035614 snRNA stem-loop binding(GO:0035614)
1.0 2.9 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
1.0 20.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
1.0 232.9 GO:0030246 carbohydrate binding(GO:0030246)
0.9 19.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.9 1.9 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.9 2.8 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.9 6.5 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.9 12.1 GO:0070628 proteasome binding(GO:0070628)
0.9 5.6 GO:0098821 BMP receptor activity(GO:0098821)
0.9 3.7 GO:0070568 guanylyltransferase activity(GO:0070568)
0.9 4.6 GO:0035184 histone threonine kinase activity(GO:0035184)
0.9 3.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.9 1.8 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.9 3.5 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.9 3.5 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.9 19.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.9 1.7 GO:0031763 galanin receptor binding(GO:0031763) type 2 galanin receptor binding(GO:0031765) type 3 galanin receptor binding(GO:0031766)
0.9 9.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.9 6.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.9 4.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.9 2.6 GO:0019809 spermidine binding(GO:0019809)
0.8 66.4 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.8 5.9 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.8 4.2 GO:1990254 keratin filament binding(GO:1990254)
0.8 27.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.8 2.5 GO:0016015 morphogen activity(GO:0016015)
0.8 11.6 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.8 6.5 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.8 4.0 GO:0070697 activin receptor binding(GO:0070697)
0.8 15.4 GO:0050661 NADP binding(GO:0050661)
0.8 4.0 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.8 8.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.8 4.7 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.8 6.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.8 31.8 GO:0005507 copper ion binding(GO:0005507)
0.8 3.0 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.8 3.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.7 1.5 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.7 18.4 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.7 2.2 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.7 5.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.7 0.7 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.7 3.6 GO:0097016 L27 domain binding(GO:0097016)
0.7 3.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.7 3.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.7 5.6 GO:0019864 IgG binding(GO:0019864)
0.7 1.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.7 11.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.7 4.1 GO:0008494 translation activator activity(GO:0008494)
0.7 13.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.7 2.0 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.7 12.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.7 4.7 GO:0050700 CARD domain binding(GO:0050700)
0.7 1.3 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.6 4.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.6 3.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.6 2.6 GO:0043404 corticotrophin-releasing factor receptor activity(GO:0015056) corticotropin-releasing hormone receptor activity(GO:0043404)
0.6 27.9 GO:0020037 heme binding(GO:0020037)
0.6 4.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.6 3.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.6 11.2 GO:0017166 vinculin binding(GO:0017166)
0.6 8.7 GO:0015250 water channel activity(GO:0015250)
0.6 8.0 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.6 2.4 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.6 1.8 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.6 1.2 GO:0050785 advanced glycation end-product receptor activity(GO:0050785)
0.6 1.2 GO:0015248 sterol transporter activity(GO:0015248)
0.6 2.9 GO:0042379 chemokine receptor binding(GO:0042379)
0.6 1.8 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.6 1.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.6 6.7 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.5 2.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.5 1.6 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.5 6.6 GO:0016505 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) peptidase activator activity involved in apoptotic process(GO:0016505)
0.5 10.3 GO:0042169 SH2 domain binding(GO:0042169)
0.5 2.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.5 2.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.5 2.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.5 4.6 GO:0016783 sulfurtransferase activity(GO:0016783)
0.5 2.0 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.5 133.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.5 10.7 GO:0005112 Notch binding(GO:0005112)
0.5 1.5 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.5 2.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.5 1.5 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.5 2.0 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.5 2.4 GO:0031433 telethonin binding(GO:0031433)
0.5 18.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.5 1.4 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.5 4.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.5 4.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.5 2.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.5 2.3 GO:0070566 adenylyltransferase activity(GO:0070566)
0.5 2.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.4 10.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4 1.3 GO:0000991 transcription factor activity, core RNA polymerase II binding(GO:0000991)
0.4 1.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.4 0.4 GO:0051425 PTB domain binding(GO:0051425)
0.4 2.5 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.4 1.3 GO:0004995 tachykinin receptor activity(GO:0004995)
0.4 1.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.4 16.7 GO:0070888 E-box binding(GO:0070888)
0.4 5.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.4 11.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.4 4.7 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.4 12.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.4 4.3 GO:0008483 transaminase activity(GO:0008483)
0.4 1.5 GO:0035514 DNA demethylase activity(GO:0035514)
0.4 4.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.4 14.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.4 131.0 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.4 7.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.3 1.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.3 2.0 GO:0036374 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.3 4.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.3 1.0 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.3 1.3 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.3 2.8 GO:0019789 SUMO transferase activity(GO:0019789)
0.3 3.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.3 0.9 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.3 16.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.3 1.1 GO:0050733 RS domain binding(GO:0050733)
0.3 2.3 GO:0046965 retinoid X receptor binding(GO:0046965)
0.3 5.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.3 6.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.3 2.2 GO:0052834 inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.3 3.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.3 1.9 GO:0034452 dynactin binding(GO:0034452)
0.3 0.8 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.3 1.3 GO:0032357 oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.3 1.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.3 5.5 GO:0043531 ADP binding(GO:0043531)
0.3 19.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.3 15.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.2 4.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 0.7 GO:0051434 BH3 domain binding(GO:0051434)
0.2 8.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2 3.8 GO:0033613 activating transcription factor binding(GO:0033613)
0.2 5.6 GO:0070001 aspartic-type peptidase activity(GO:0070001)
0.2 0.7 GO:0004058 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.2 0.4 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.2 1.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 0.6 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.2 2.3 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.2 1.7 GO:0004966 galanin receptor activity(GO:0004966)
0.2 0.6 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.2 0.6 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.2 1.0 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.2 0.4 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.2 3.8 GO:0031369 translation initiation factor binding(GO:0031369)
0.2 0.4 GO:0019865 immunoglobulin binding(GO:0019865)
0.2 0.7 GO:0004948 calcitonin receptor activity(GO:0004948)
0.2 6.5 GO:0070063 RNA polymerase binding(GO:0070063)
0.2 1.7 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 2.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 0.7 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 4.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 5.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 2.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 0.2 GO:0001635 calcitonin gene-related peptide receptor activity(GO:0001635)
0.1 3.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 10.5 GO:0004540 ribonuclease activity(GO:0004540)
0.1 0.7 GO:0097617 annealing activity(GO:0097617)
0.1 2.1 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.1 5.0 GO:0003823 antigen binding(GO:0003823)
0.1 0.4 GO:0000150 recombinase activity(GO:0000150)
0.1 0.2 GO:0004335 galactokinase activity(GO:0004335)
0.1 0.5 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 1.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 2.8 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.1 1.1 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.1 1.2 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.4 GO:0071253 connexin binding(GO:0071253)
0.1 0.3 GO:0031404 chloride ion binding(GO:0031404)
0.1 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.5 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.4 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 1.0 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 1.4 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.1 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 2.4 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.4 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.2 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 1.0 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.3 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.3 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 7.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
8.2 253.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
6.4 19.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
6.3 69.1 ST JAK STAT PATHWAY Jak-STAT Pathway
4.4 241.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
3.5 147.0 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
3.4 57.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
2.9 667.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
2.3 87.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
2.2 31.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
2.1 46.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
2.1 59.5 PID IL1 PATHWAY IL1-mediated signaling events
1.9 30.7 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
1.9 51.5 PID EPO PATHWAY EPO signaling pathway
1.9 38.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
1.6 55.9 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
1.4 33.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
1.4 31.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
1.4 15.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
1.4 8.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
1.4 15.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
1.3 37.3 PID BCR 5PATHWAY BCR signaling pathway
1.3 36.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
1.2 11.1 PID IGF1 PATHWAY IGF1 pathway
1.2 7.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
1.2 5.8 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
1.2 18.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
1.1 8.0 PID ALK2 PATHWAY ALK2 signaling events
1.1 47.3 PID AURORA B PATHWAY Aurora B signaling
1.1 6.4 PID IL2 1PATHWAY IL2-mediated signaling events
1.1 76.3 PID CMYB PATHWAY C-MYB transcription factor network
1.0 10.4 PID GMCSF PATHWAY GMCSF-mediated signaling events
1.0 42.0 PID HNF3A PATHWAY FOXA1 transcription factor network
1.0 40.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
1.0 2.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.9 2.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.9 12.8 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.8 13.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.8 17.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.7 1.5 PID MYC PATHWAY C-MYC pathway
0.7 34.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.7 56.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.7 28.1 PID BMP PATHWAY BMP receptor signaling
0.7 16.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.7 8.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.6 7.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.6 10.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.6 19.9 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.6 8.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.5 2.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.5 29.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.5 81.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.5 7.9 PID ALK1 PATHWAY ALK1 signaling events
0.5 16.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.5 4.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.5 16.3 PID P73PATHWAY p73 transcription factor network
0.5 13.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.5 3.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.5 7.2 PID IL23 PATHWAY IL23-mediated signaling events
0.4 12.5 PID BARD1 PATHWAY BARD1 signaling events
0.4 2.7 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.4 16.0 PID E2F PATHWAY E2F transcription factor network
0.4 20.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.4 13.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.4 7.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.4 8.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.4 5.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.4 1.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.4 7.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.3 2.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.3 8.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.3 0.9 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.3 3.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 11.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.2 1.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 2.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.2 5.7 PID P53 REGULATION PATHWAY p53 pathway
0.2 2.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 2.5 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 2.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 0.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 0.6 PID CD40 PATHWAY CD40/CD40L signaling
0.0 8.0 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.7 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
13.8 13.8 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
13.7 136.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
13.3 265.2 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
12.0 36.0 REACTOME XENOBIOTICS Genes involved in Xenobiotics
11.5 160.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
10.5 63.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
9.6 172.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
9.2 175.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
7.0 69.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
7.0 222.4 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
6.7 113.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
6.3 94.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
5.9 70.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
5.4 80.3 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
5.1 131.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
5.0 5.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
4.8 43.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
4.6 22.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
3.9 31.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
3.9 54.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
3.8 46.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
3.6 7.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
3.6 49.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
3.5 14.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
3.5 27.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
3.5 100.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
3.4 6.7 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
3.3 43.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
3.3 26.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
3.3 36.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
3.2 45.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
3.0 14.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
2.9 44.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
2.8 22.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
2.8 142.5 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
2.7 21.9 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
2.7 18.9 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
2.5 42.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
2.4 48.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
2.4 97.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
2.3 27.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
2.1 22.8 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
2.1 32.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
2.0 26.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
2.0 4.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
2.0 25.7 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
1.9 115.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
1.9 84.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
1.8 58.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
1.7 8.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
1.7 18.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
1.7 20.0 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
1.6 64.0 REACTOME AMYLOIDS Genes involved in Amyloids
1.6 27.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
1.6 17.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
1.5 7.5 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
1.5 28.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
1.5 15.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
1.5 17.7 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
1.4 47.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
1.4 209.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
1.4 15.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
1.4 23.8 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
1.4 8.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
1.3 18.9 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.3 17.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
1.3 5.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
1.3 144.8 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
1.2 21.2 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
1.2 22.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
1.2 9.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
1.1 10.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
1.1 7.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
1.1 26.3 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
1.1 16.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.1 50.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
1.0 2.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
1.0 3.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
1.0 18.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.9 9.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.9 13.1 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.9 4.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.9 6.6 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.9 21.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.9 15.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.9 2.7 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.9 6.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.9 2.6 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.9 12.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.9 4.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.8 91.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.8 10.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.8 3.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.8 6.3 REACTOME SIGNALING BY ILS Genes involved in Signaling by Interleukins
0.8 9.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.8 10.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.7 17.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.7 8.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.7 9.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.7 8.0 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.7 11.8 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.7 5.9 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.6 7.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.6 1.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.6 1.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.6 23.9 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.6 10.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.6 8.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.6 10.6 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.6 11.1 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.6 26.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.6 9.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.6 9.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.6 5.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.6 5.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.5 1.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.5 3.3 REACTOME SIGNALLING TO RAS Genes involved in Signalling to RAS
0.5 18.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.5 14.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.5 9.4 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.5 11.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.5 26.5 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.5 10.8 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.5 10.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.4 3.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.4 16.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.4 6.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.4 1.6 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.4 4.0 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.4 2.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.4 2.2 REACTOME RNA POL II TRANSCRIPTION Genes involved in RNA Polymerase II Transcription
0.3 10.3 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.3 3.7 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.3 4.4 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.3 6.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.3 6.0 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.3 3.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.3 5.2 REACTOME BASE EXCISION REPAIR Genes involved in Base Excision Repair
0.3 1.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.3 3.0 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.3 4.7 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.3 10.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.3 4.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.3 0.8 REACTOME DEFENSINS Genes involved in Defensins
0.3 4.8 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.2 1.1 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.2 7.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 5.6 REACTOME CHROMOSOME MAINTENANCE Genes involved in Chromosome Maintenance
0.2 3.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.2 2.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 3.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.2 10.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 3.5 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.2 0.7 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.2 3.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 2.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 2.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 3.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 2.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.3 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.1 1.2 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 2.6 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 0.9 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 1.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 0.8 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 4.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation