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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Six6

Z-value: 0.87

Motif logo

Transcription factors associated with Six6

Gene Symbol Gene ID Gene Info
ENSRNOG00000006296 SIX homeobox 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Six6rn6_v1_chr6_+_95816749_95816749-0.165.3e-03Click!

Activity profile of Six6 motif

Sorted Z-values of Six6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_75144903 45.92 ENSRNOT00000002329
HRAS-like suppressor
chr16_+_68633720 40.49 ENSRNOT00000081838
sperm motility kinase-like
chr3_+_70327193 39.14 ENSRNOT00000089165
fibrous sheath-interacting protein 2
chr11_+_52828116 38.57 ENSRNOT00000035340
coiled-coil domain containing 54
chr16_-_54628458 29.22 ENSRNOT00000042587
ADAM metallopeptidase domain 24
chr1_-_201702963 26.95 ENSRNOT00000031258
similar to RIKEN cDNA 1700022C21
chr15_-_5417570 26.58 ENSRNOT00000061525
Spetex-2F protein
chr6_-_86223052 26.18 ENSRNOT00000046828
fibrous sheath CABYR binding protein
chr12_+_24158766 25.84 ENSRNOT00000001963
C-C motif chemokine ligand 26
chr9_+_53440272 25.69 ENSRNOT00000059159
hypothetical protein LOC685203
chr9_-_114327767 25.54 ENSRNOT00000085481

chr9_-_105376935 24.97 ENSRNOT00000043386
solute carrier organic anion transporter family, member 6d1
chr16_+_52169450 24.13 ENSRNOT00000019474
tripartite motif family-like 1
chr10_-_35058870 23.97 ENSRNOT00000079481

chr2_-_124047044 23.08 ENSRNOT00000065384
centrin 4
chr4_+_45567573 20.89 ENSRNOT00000089824
ankyrin repeat domain 7
chr5_+_122508388 20.42 ENSRNOT00000038410
Tctex1 domain containing 1
chr16_+_51730452 20.02 ENSRNOT00000078614
a disintegrin and metalloprotease domain 34-like
chr9_-_104870382 19.96 ENSRNOT00000084398
solute carrier organic anion transporter family, member 6d1
chr2_+_208541361 19.81 ENSRNOT00000021288
transmembrane and immunoglobulin domain containing 3
chrX_+_147493880 19.61 ENSRNOT00000037881
similar to melanoma antigen family A, 5
chr3_-_173944396 19.47 ENSRNOT00000079019
synaptonemal complex protein 2
chr16_-_12194118 19.24 ENSRNOT00000071517
similar to hypothetical protein 4930474N05
chr11_-_1437732 19.10 ENSRNOT00000037345
casein kinase 2, alpha prime interacting protein
chr1_+_106405002 19.10 ENSRNOT00000074027
probable isocitrate dehydrogenase [NAD] gamma 2, mitochondrial
chr18_-_13194952 18.76 ENSRNOT00000092925
coiled-coil domain containing 178
chr5_+_162127810 18.75 ENSRNOT00000038858
PRAME family member 27
chr2_+_92573004 18.48 ENSRNOT00000065774
GTPase activating protein testicular GAP1
chr3_+_161121697 18.03 ENSRNOT00000036020
WAP four-disulfide core domain 10A
chr2_-_137404996 17.91 ENSRNOT00000090907
similar to T-cell activation Rho GTPase-activating protein isoform b
chr9_+_17734345 17.89 ENSRNOT00000067104
calpain 11
chrY_+_380382 17.32 ENSRNOT00000092110
RNA binding motif protein, Y-linked, family 1, member J
chr2_+_127538659 17.27 ENSRNOT00000093483
ENSRNOT00000058476
solute carrier family 25 member 31
chr15_+_47470863 17.23 ENSRNOT00000072438
similar to Plasma kallikrein precursor (Plasma prekallikrein) (Kininogenin) (Fletcher factor)
chr11_-_36533073 17.00 ENSRNOT00000033486
LCA5L, lebercilin like
chr4_-_160803558 16.89 ENSRNOT00000049542
Sumo1/sentrin/SMT3 specific peptidase 18
chrX_+_125314613 16.84 ENSRNOT00000029193
hypothetical protein LOC691215
chr13_-_100189778 16.66 ENSRNOT00000071062
uncharacterized LOC100912759
chr9_-_113246545 16.51 ENSRNOT00000034759
transmembrane protein 232
chr10_-_91581232 16.32 ENSRNOT00000066453
ENSRNOT00000068686

chr18_+_47613854 16.28 ENSRNOT00000025270
zinc finger protein 474
chr10_+_57239993 16.00 ENSRNOT00000067919
hypothetical protein LOC687707
chr3_-_161040511 15.96 ENSRNOT00000037518
WAP four-disulfide core domain 6A
chr9_+_24066303 15.95 ENSRNOT00000018163
cysteine-rich secretory protein 3
chrX_+_43745604 15.91 ENSRNOT00000040825
rCG36365-like
chr9_+_93445002 15.69 ENSRNOT00000025029
similar to hypothetical protein MGC35154
chr4_-_161091010 15.43 ENSRNOT00000043708
Sumo1/sentrin/SMT3 specific peptidase 17
chr17_+_59714657 15.36 ENSRNOT00000035675
similar to ankyrin repeat domain 26
chr20_+_13498926 15.14 ENSRNOT00000070992
ENSRNOT00000045375
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr8_-_96547568 15.06 ENSRNOT00000078343
similar to RIKEN cDNA 4930579C12 gene
chr5_+_69809495 14.98 ENSRNOT00000059828
nipsnap homolog 3A (C. elegans)
chr6_-_55711146 14.94 ENSRNOT00000036996
leucine rich repeat containing 72
chr7_+_129595192 14.91 ENSRNOT00000071151
zinc finger, DHHC-type containing 25
chr14_-_1505085 14.89 ENSRNOT00000090361
uncharacterized LOC102554799
chr5_-_58288125 14.82 ENSRNOT00000068752
family with sequence similarity 205, member A
chr14_+_107785029 14.78 ENSRNOT00000013097
ENSRNOT00000087091
family with sequence similarity 161, member A
chr15_+_33885106 14.73 ENSRNOT00000024483
dehydrogenase/reductase 2
chr17_+_5311274 14.56 ENSRNOT00000067020
spermatogenesis-associated protein 31D1-like
chr11_-_88092756 14.16 ENSRNOT00000002542
YdjC homolog (bacterial)
chr18_-_13183263 13.88 ENSRNOT00000050933
coiled-coil domain containing 178
chr1_+_97712177 13.37 ENSRNOT00000027745
similar to RIKEN cDNA 4930433I11 gene
chrX_+_96667863 13.27 ENSRNOT00000042552
similar to hypothetical protein 4932411N23
chr2_-_148838441 13.14 ENSRNOT00000018294
glutamate-rich 6
chrX_+_78991223 13.06 ENSRNOT00000031200
family with sequence similarity 46, member D
chrX_+_151745455 12.89 ENSRNOT00000041429
similar to RNA polymerase II elongation factor ELL2
chrX_+_74273182 12.88 ENSRNOT00000003922
testis specific X-linked gene
chr3_-_14571640 12.87 ENSRNOT00000060013
glycoprotein, alpha-galactosyltransferase 1-like 1
chr16_+_12174370 12.79 ENSRNOT00000072045
ral guanine nucleotide dissociation stimulator-like
chr1_+_89149998 12.76 ENSRNOT00000056742
hypothetical protein LOC688924
chr2_+_208749996 12.51 ENSRNOT00000086321
chitinase, acidic
chr1_+_101412736 12.49 ENSRNOT00000067468
luteinizing hormone beta polypeptide
chrX_-_38468360 12.43 ENSRNOT00000045285
MAP7 domain containing 2
chr9_-_50820290 12.14 ENSRNOT00000050748
uncharacterized LOC102548013
chr15_+_17834635 11.99 ENSRNOT00000085530
similar to RIKEN cDNA 4933406L09
chr6_-_105160470 11.97 ENSRNOT00000008367
a disintegrin and metalloprotease domain 4
chr5_-_107858104 11.87 ENSRNOT00000092196
cyclin-dependent kinase inhibitor 2B
chr11_+_14005732 11.75 ENSRNOT00000047240
RNA binding motif protein 11
chr14_-_77810147 11.59 ENSRNOT00000035427
cytokine like 1
chr9_+_60883981 11.56 ENSRNOT00000081002
coiled-coil domain containing 150
chr1_+_190914946 11.42 ENSRNOT00000039447
similar to F28B3.5a
chr11_-_61234944 11.41 ENSRNOT00000059680
cilia and flagella associated protein 44
chr14_+_83560541 11.23 ENSRNOT00000057738
ENSRNOT00000085228
phosphoinositide-3-kinase interacting protein 1
chrX_-_97262013 11.22 ENSRNOT00000040168
claudin 34C4
chr10_+_90984227 11.08 ENSRNOT00000003890
ENSRNOT00000093707
coiled-coil domain containing 103
chr15_-_49666888 11.07 ENSRNOT00000041154

chr15_-_104168564 11.06 ENSRNOT00000093385
ENSRNOT00000038596
DAZ interacting zinc finger protein 1
chr7_+_95309928 11.05 ENSRNOT00000005887
MDM2 binding protein
chr2_+_208750356 11.00 ENSRNOT00000041562
chitinase, acidic
chr1_-_87155118 10.95 ENSRNOT00000072441

chr7_-_130350570 10.82 ENSRNOT00000055805
outer dense fiber of sperm tails 3B
chr13_-_47916185 10.82 ENSRNOT00000087793
dual specificity tyrosine phosphorylation regulated kinase 3
chr2_+_189106039 10.80 ENSRNOT00000028210
ubiquitin conjugating enzyme E2 Q1
chr5_+_138245639 10.55 ENSRNOT00000066169
small vasohibin binding protein
chr16_+_12510827 10.54 ENSRNOT00000077763

chrX_-_83788325 10.40 ENSRNOT00000037149
spermidine/spermine N1-acetyl transferase-like 1
chr19_-_28148135 10.24 ENSRNOT00000090797

chr18_-_37776453 10.23 ENSRNOT00000087876
dihydropyrimidinase-like 3
chr3_-_26056818 10.19 ENSRNOT00000044209
LDL receptor related protein 1B
chr1_-_90057923 10.07 ENSRNOT00000028674
programmed cell death 2-like
chr6_+_48452369 10.05 ENSRNOT00000044310
myelin transcription factor 1-like
chr13_-_6712734 9.99 ENSRNOT00000061683

chr9_+_88133884 9.88 ENSRNOT00000077265
rhomboid domain containing 1
chr15_+_5783951 9.72 ENSRNOT00000061040
similar to glutaredoxin 1 (thioltransferase); glutaredoxin
chr11_-_90234286 9.60 ENSRNOT00000071986
EF hand calcium binding domain 1
chr18_+_51523758 9.47 ENSRNOT00000078518
GRAM domain containing 3
chr1_-_178195948 9.37 ENSRNOT00000081767
BTB domain containing 10
chr4_-_80395502 9.26 ENSRNOT00000014437
neuropeptide VF precursor
chr1_-_100530183 9.26 ENSRNOT00000067754
myosin binding protein C, fast-type
chr16_+_13050305 9.25 ENSRNOT00000077388

chr17_-_42740021 9.24 ENSRNOT00000023063
Prolactin family 3, subfamily a, member 1
chr9_-_121725716 9.22 ENSRNOT00000087405
adenylate cyclase activating polypeptide 1
chr7_+_140248852 9.14 ENSRNOT00000087338
hypothetical LOC300207
chr8_-_16486419 9.07 ENSRNOT00000033223
similar to MAP/microtubule affinity-regulating kinase 4 (MAP/microtubule affinity-regulating kinase-like 1)
chr4_+_8066907 8.84 ENSRNOT00000080811
SRSF protein kinase 2
chr14_-_21615488 8.82 ENSRNOT00000002667
variable coding sequence A2
chr18_-_67224566 8.77 ENSRNOT00000064947
DCC netrin 1 receptor
chr1_+_102414625 8.75 ENSRNOT00000089488
potassium voltage-gated channel subfamily C member 1
chr6_-_1942972 8.54 ENSRNOT00000048711
CDC42 effector protein 3
chr1_-_99135977 8.54 ENSRNOT00000056515
vomeronasal 2 receptor, 38
chr18_+_84162467 8.49 ENSRNOT00000047841
similar to melanoma antigen family A, 6
chr19_+_26985450 8.47 ENSRNOT00000087468

chr2_-_137153551 8.42 ENSRNOT00000083443

chr5_+_124442293 8.38 ENSRNOT00000041922
similar to novel protein
chr4_-_181348799 8.24 ENSRNOT00000033743
hypothetical protein LOC690783
chr8_+_96395317 8.10 ENSRNOT00000044521
tripartite motif-containing 43A
chr20_-_13458110 8.08 ENSRNOT00000072183
solute carrier family 5 member 4
chr7_-_120874308 8.05 ENSRNOT00000078320
family with sequence similarity 227, member A
chr18_-_30802242 7.85 ENSRNOT00000064799
RGD1563159
chr8_+_91368111 7.81 ENSRNOT00000083151
Ttk protein kinase
chr11_-_1836897 7.74 ENSRNOT00000050533
zinc finger protein 654
chr8_-_37026142 7.65 ENSRNOT00000060446
rCG22807-like
chr2_-_195279218 7.55 ENSRNOT00000085565
similar to TDPOZ3
chr14_-_78469480 7.55 ENSRNOT00000006771
janus kinase and microtubule interacting protein 1
chr1_+_215610368 7.49 ENSRNOT00000078903
ENSRNOT00000087781
troponin I2, fast skeletal type
chr9_+_23354770 7.45 ENSRNOT00000081459
centromere protein Q
chr13_+_71322759 7.41 ENSRNOT00000071815
transmembrane epididymal protein 1
chr14_+_51959745 7.33 ENSRNOT00000083767

chr1_+_107262659 7.32 ENSRNOT00000022499
growth arrest-specific 2
chr2_+_211159062 7.22 ENSRNOT00000027099
myosin binding protein H-like
chr2_-_195935878 7.18 ENSRNOT00000028440
cingulin
chr8_-_17524839 7.13 ENSRNOT00000081679
N-acetylated alpha-linked acidic dipeptidase 2
chr3_-_118635268 7.12 ENSRNOT00000086357
ATPase phospholipid transporting 8B4 (putative)
chr8_-_111101416 7.09 ENSRNOT00000084413
centrosomal protein 63
chr10_+_53713938 7.01 ENSRNOT00000004236
ENSRNOT00000086599
ENSRNOT00000085582
myosin heavy chain 2
chr1_+_245237736 6.93 ENSRNOT00000035814
very low density lipoprotein receptor
chr8_-_5631014 6.88 ENSRNOT00000011884
matrix metallopeptidase 1b (interstitial collagenase)
chr1_+_211351350 6.77 ENSRNOT00000082751
ENSRNOT00000030461
janus kinase and microtubule interacting protein 3
chr4_+_8066737 6.76 ENSRNOT00000063994
SRSF protein kinase 2
chr14_-_37294472 6.68 ENSRNOT00000081087
defective in cullin neddylation 1 domain containing 4
chr1_-_221087449 6.54 ENSRNOT00000016987
family with sequence similarity 89, member B
chr9_+_41045363 6.54 ENSRNOT00000066284
cripto, FRL-1, cryptic family 1
chr10_+_16259728 6.33 ENSRNOT00000028115
biorientation of chromosomes in cell division 1
chr8_-_5202360 6.26 ENSRNOT00000089124

chr2_-_185303610 6.18 ENSRNOT00000093479
ENSRNOT00000046286
protease, serine 48
chr5_-_74190991 6.14 ENSRNOT00000090366
erythrocyte membrane protein band 4.1 like 4B
chr9_+_95398237 6.10 ENSRNOT00000025879
transient receptor potential cation channel, subfamily M, member 8
chr15_+_18920373 6.06 ENSRNOT00000036754
mCG11429-like
chr7_+_77678968 5.94 ENSRNOT00000006917
ATPase H+ transporting V1 subunit C1
chr9_-_19978013 5.88 ENSRNOT00000038222
phospholipase A2 group VII
chr7_+_30699476 5.88 ENSRNOT00000059269
ankyrin repeat and sterile alpha motif domain containing 1B
chr4_+_152630469 5.80 ENSRNOT00000013721
ninjurin 2
chr20_+_14577166 5.72 ENSRNOT00000085583
rhabdoid tumor deletion region gene 1
chr19_+_15033108 5.67 ENSRNOT00000021812
carboxylesterase 1D
chr10_-_89338739 5.63 ENSRNOT00000073923
prostaglandin E synthase 3 like
chr1_-_81127059 5.55 ENSRNOT00000026252
zinc finger protein 94
chr12_-_17904254 5.54 ENSRNOT00000060192
similar to Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead-related transcription factor 7) (FREAC-7)
chr1_+_23409408 5.50 ENSRNOT00000022362
EYA transcriptional coactivator and phosphatase 4
chr5_+_25391115 5.45 ENSRNOT00000021612
cadherin 17
chr8_+_76426335 5.44 ENSRNOT00000085496
general transcription factor2A subunit 2
chr20_-_795286 5.43 ENSRNOT00000052186
olfactory receptor 1691
chrX_+_145558840 5.37 ENSRNOT00000032522
RIKEN cDNA 4931400O07 gene
chrX_-_77529374 5.34 ENSRNOT00000078213
fibronectin type III domain containing 3C1
chr19_-_49623758 5.29 ENSRNOT00000071130
polycystic kidney disease 1-like 2
chr10_-_16689321 5.26 ENSRNOT00000028173
BCL2/adenovirus E1B interacting protein 1
chr10_-_13107771 5.23 ENSRNOT00000005879
FLYWCH-type zinc finger 1
chr2_+_150106292 5.19 ENSRNOT00000073078
arylacetamide deacetylase-like 2-like
chr10_+_103972888 5.19 ENSRNOT00000067838
potassium channel tetramerization domain containing 2
chr17_+_35677984 5.14 ENSRNOT00000024609
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr1_+_171188133 5.08 ENSRNOT00000026511
olfactory receptor 231
chr5_-_77945016 5.07 ENSRNOT00000076223
zinc finger protein 37
chr17_-_42737000 4.98 ENSRNOT00000077923
Prolactin family 3, subfamily a, member 1
chr19_+_15195565 4.87 ENSRNOT00000090865
ENSRNOT00000078874
carboxylesterase 1D
chr5_-_169301728 4.83 ENSRNOT00000013646
espin
chr8_+_84945444 4.82 ENSRNOT00000008244
kelch-like family member 31
chr3_-_102484517 4.81 ENSRNOT00000006522
olfactory receptor 750
chrX_-_77418525 4.78 ENSRNOT00000092303
fibronectin type III domain containing 3C1
chr4_-_67206426 4.77 ENSRNOT00000013124
makorin ring finger protein 1
chr2_+_5437067 4.63 ENSRNOT00000093516
POU domain class 5, transcription factor 2
chr3_+_56966654 4.48 ENSRNOT00000088097
golgi reassembly stacking protein 2
chr5_-_157059508 4.42 ENSRNOT00000022282
von Willebrand factor A domain containing 5B1
chrX_-_142248369 4.33 ENSRNOT00000091330
fibroblast growth factor 13
chr7_-_117773134 4.24 ENSRNOT00000045135
RecQ like helicase 4
chr10_+_106991935 4.15 ENSRNOT00000004007
phosphatidylglycerophosphate synthase 1
chr1_+_27476375 4.14 ENSRNOT00000047224
ENSRNOT00000075427
sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2-like
chr8_-_71055969 4.12 ENSRNOT00000075734
ankyrin repeat and death domain containing 1A
chr17_+_77195247 4.06 ENSRNOT00000081940
optineurin
chr3_-_94419048 4.06 ENSRNOT00000015775
homeodomain interacting protein kinase 3
chr11_-_61470348 4.05 ENSRNOT00000083841
N-alpha-acetyltransferase 50-like
chr16_-_19544727 4.01 ENSRNOT00000074514
zinc finger protein 617
chr7_-_95310005 3.98 ENSRNOT00000005815
mitochondrial ribosomal protein L13

Network of associatons between targets according to the STRING database.

First level regulatory network of Six6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.3 29.2 GO:0060468 prevention of polyspermy(GO:0060468)
4.7 23.5 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
3.8 45.9 GO:0046485 ether lipid metabolic process(GO:0046485)
3.7 11.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
3.5 10.5 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
3.3 9.9 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
3.1 15.6 GO:0035063 nuclear speck organization(GO:0035063)
2.8 16.9 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
2.6 7.8 GO:0044785 metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
2.5 49.6 GO:0035404 histone-serine phosphorylation(GO:0035404)
2.3 9.2 GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
2.2 8.8 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
2.2 6.5 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
2.2 10.8 GO:0035617 stress granule disassembly(GO:0035617)
2.1 10.4 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
1.9 11.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
1.8 5.4 GO:0002314 germinal center B cell differentiation(GO:0002314)
1.7 6.9 GO:0034436 glycoprotein transport(GO:0034436) reelin-mediated signaling pathway(GO:0038026)
1.6 16.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
1.6 6.5 GO:0060459 left lung development(GO:0060459) left lung morphogenesis(GO:0060460)
1.6 3.1 GO:0048850 hypophysis morphogenesis(GO:0048850)
1.5 5.9 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441) platelet activating factor metabolic process(GO:0046469)
1.5 8.7 GO:0021759 globus pallidus development(GO:0021759)
1.4 25.8 GO:0010818 T cell chemotaxis(GO:0010818)
1.2 6.1 GO:0050955 thermoception(GO:0050955)
1.2 10.8 GO:0070459 prolactin secretion(GO:0070459)
1.2 12.9 GO:0030259 lipid glycosylation(GO:0030259)
1.2 7.0 GO:0031034 myosin filament assembly(GO:0031034)
1.1 11.1 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
1.0 7.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.9 9.3 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.9 10.5 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.9 2.6 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.8 2.4 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.7 4.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.7 4.8 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.7 10.2 GO:0051764 actin crosslink formation(GO:0051764)
0.7 3.4 GO:0090168 Golgi reassembly(GO:0090168)
0.7 3.4 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.7 2.6 GO:0061055 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055)
0.6 17.9 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.6 3.1 GO:0097168 mesenchymal stem cell proliferation(GO:0097168)
0.6 4.3 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.6 6.1 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.6 5.5 GO:0016576 histone dephosphorylation(GO:0016576)
0.6 1.8 GO:0035425 autocrine signaling(GO:0035425)
0.6 3.0 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.6 6.9 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.6 3.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.5 11.4 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.5 4.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.5 1.5 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.5 1.9 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.5 2.8 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.5 11.9 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.4 13.6 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.4 4.1 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.4 1.6 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.4 2.4 GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
0.4 12.1 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.4 13.5 GO:0030823 regulation of cGMP metabolic process(GO:0030823)
0.4 1.5 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.3 2.7 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.3 3.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.3 6.7 GO:0045116 protein neddylation(GO:0045116)
0.3 11.1 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.3 4.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.3 3.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.3 3.4 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.3 3.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 1.0 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.2 5.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.2 3.9 GO:0060134 prepulse inhibition(GO:0060134)
0.2 2.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.2 1.0 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.2 3.3 GO:0006415 translational termination(GO:0006415)
0.2 1.1 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.2 3.6 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.2 0.7 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.2 0.5 GO:0060545 positive regulation of necroptotic process(GO:0060545)
0.2 1.2 GO:0019388 galactose catabolic process(GO:0019388)
0.1 1.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 1.6 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 7.2 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.1 0.9 GO:0048539 bone marrow development(GO:0048539)
0.1 3.5 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 1.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 6.3 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1 3.1 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 1.0 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 3.2 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.5 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429) positive regulation of t-circle formation(GO:1904431)
0.1 1.1 GO:0097264 self proteolysis(GO:0097264)
0.1 5.3 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 2.7 GO:0034629 cellular protein complex localization(GO:0034629)
0.1 0.5 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 5.8 GO:0042246 tissue regeneration(GO:0042246)
0.1 14.9 GO:0044782 cilium organization(GO:0044782)
0.1 4.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 14.1 GO:0009566 fertilization(GO:0009566)
0.1 5.9 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.1 6.2 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 3.6 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.8 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 1.2 GO:0031424 keratinization(GO:0031424)
0.1 0.9 GO:0097499 protein localization to nonmotile primary cilium(GO:0097499)
0.1 0.8 GO:0036010 protein localization to endosome(GO:0036010)
0.1 2.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.9 GO:0019236 response to pheromone(GO:0019236)
0.1 1.0 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.9 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 1.2 GO:0048520 positive regulation of behavior(GO:0048520)
0.1 6.3 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.1 4.5 GO:0007030 Golgi organization(GO:0007030)
0.0 3.8 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.3 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 1.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 1.0 GO:0006379 mRNA cleavage(GO:0006379)
0.0 1.2 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 3.0 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.8 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 10.1 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.0 4.2 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 8.3 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.8 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 3.2 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.0 0.3 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 15.7 GO:0006508 proteolysis(GO:0006508)
0.0 0.8 GO:0002028 regulation of sodium ion transport(GO:0002028)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 45.9 GO:0005641 nuclear envelope lumen(GO:0005641)
2.8 49.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
1.5 26.2 GO:0035686 sperm fibrous sheath(GO:0035686)
1.4 16.5 GO:0005859 muscle myosin complex(GO:0005859)
1.2 9.9 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
1.2 5.9 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
1.1 8.8 GO:0032584 growth cone membrane(GO:0032584)
0.9 15.9 GO:0042581 specific granule(GO:0042581)
0.9 19.5 GO:0000800 lateral element(GO:0000800)
0.9 11.1 GO:0097539 ciliary transition fiber(GO:0097539)
0.8 7.0 GO:0005826 actomyosin contractile ring(GO:0005826)
0.6 7.5 GO:0005861 troponin complex(GO:0005861)
0.5 3.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.5 5.9 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.5 5.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.4 3.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.4 4.5 GO:0005797 Golgi medial cisterna(GO:0005797)
0.4 16.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.4 1.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.4 4.8 GO:0032426 stereocilium tip(GO:0032426)
0.4 17.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 3.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.3 2.7 GO:0061700 GATOR2 complex(GO:0061700)
0.3 2.0 GO:0005655 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.3 47.4 GO:0005923 bicellular tight junction(GO:0005923)
0.3 3.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.3 2.8 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.3 37.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.3 10.2 GO:0031941 filamentous actin(GO:0031941)
0.2 8.4 GO:0001772 immunological synapse(GO:0001772)
0.2 9.8 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2 2.8 GO:0051286 cell tip(GO:0051286)
0.2 28.3 GO:0000776 kinetochore(GO:0000776)
0.2 3.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 11.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 1.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.2 1.4 GO:0044305 calyx of Held(GO:0044305)
0.2 2.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 2.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 2.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 0.5 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.1 10.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 8.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 8.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 10.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 7.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 6.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 0.7 GO:0036449 microtubule minus-end(GO:0036449)
0.1 5.3 GO:0031201 SNARE complex(GO:0031201)
0.1 4.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 5.1 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 8.6 GO:0000922 spindle pole(GO:0000922)
0.1 1.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 15.0 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.1 3.4 GO:0005795 Golgi stack(GO:0005795)
0.1 0.5 GO:0044194 cytolytic granule(GO:0044194)
0.1 2.9 GO:0016592 mediator complex(GO:0016592)
0.0 1.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 2.7 GO:0005901 caveola(GO:0005901)
0.0 0.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 2.6 GO:0016605 PML body(GO:0016605)
0.0 0.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 4.0 GO:0005770 late endosome(GO:0005770)
0.0 4.3 GO:0043204 perikaryon(GO:0043204)
0.0 2.7 GO:0001650 fibrillar center(GO:0001650)
0.0 5.0 GO:0005874 microtubule(GO:0005874)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 3.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 26.6 GO:0005739 mitochondrion(GO:0005739)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.6 25.8 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
4.8 19.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
3.9 23.5 GO:0004568 chitinase activity(GO:0004568)
3.5 10.4 GO:0019809 spermidine binding(GO:0019809)
3.3 49.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
3.2 12.9 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
2.9 14.7 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
2.6 10.5 GO:0004771 sterol esterase activity(GO:0004771)
2.3 6.9 GO:0034437 glycoprotein transporter activity(GO:0034437)
1.8 5.4 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
1.8 8.8 GO:0005042 netrin receptor activity(GO:0005042)
1.4 13.6 GO:0005412 glucose:sodium symporter activity(GO:0005412)
1.3 10.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.3 16.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
1.1 7.5 GO:0031014 troponin T binding(GO:0031014)
1.1 8.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
1.0 25.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
1.0 5.9 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.9 2.6 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.9 7.8 GO:0043515 kinetochore binding(GO:0043515)
0.8 11.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.8 6.5 GO:0070697 activin receptor binding(GO:0070697)
0.8 4.1 GO:0001155 TFIIIA-class transcription factor binding(GO:0001155)
0.8 2.4 GO:0099567 N-terminal myristoylation domain binding(GO:0031997) calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099567)
0.7 17.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.7 4.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.7 11.9 GO:0097602 cullin family protein binding(GO:0097602)
0.7 2.7 GO:0055100 adiponectin binding(GO:0055100)
0.7 5.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.6 5.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.6 7.5 GO:0050811 GABA receptor binding(GO:0050811)
0.6 11.8 GO:0008266 poly(U) RNA binding(GO:0008266)
0.6 2.2 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.5 3.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.5 65.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.5 4.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.5 3.0 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.5 1.5 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.5 13.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.4 21.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.4 8.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.4 8.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.4 13.2 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.4 3.9 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.4 9.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.3 3.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.3 32.1 GO:0004620 phospholipase activity(GO:0004620)
0.3 10.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.3 6.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.3 2.8 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.3 10.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.3 11.2 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.3 3.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 1.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 3.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 5.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 1.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 24.3 GO:0005179 hormone activity(GO:0005179)
0.2 3.3 GO:0008171 O-methyltransferase activity(GO:0008171)
0.2 5.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 4.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 3.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 5.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 2.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 3.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 2.9 GO:0042923 neuropeptide binding(GO:0042923)
0.1 23.6 GO:0008017 microtubule binding(GO:0008017)
0.1 1.8 GO:0001618 virus receptor activity(GO:0001618)
0.1 15.3 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.1 0.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 3.4 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.1 0.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.5 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 3.8 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.1 11.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.8 GO:0032183 SUMO binding(GO:0032183)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103) TBP-class protein binding(GO:0017025)
0.0 8.3 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 23.0 GO:0005198 structural molecule activity(GO:0005198)
0.0 1.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.0 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 5.7 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.0 GO:0030276 clathrin binding(GO:0030276)
0.0 0.6 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 1.8 GO:0008233 peptidase activity(GO:0008233)
0.0 6.8 GO:0005509 calcium ion binding(GO:0005509)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 25.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.3 11.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.3 8.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 7.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 3.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 1.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 7.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 7.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 3.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 2.8 ST GA13 PATHWAY G alpha 13 Pathway
0.1 0.8 PID IL1 PATHWAY IL1-mediated signaling events
0.0 2.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 8.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 12.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.7 9.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.4 16.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.4 5.9 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.4 7.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4 9.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.3 19.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.3 3.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.3 7.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.3 7.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 3.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 2.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 9.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.2 3.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 3.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 8.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 7.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 3.8 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 9.1 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.1 2.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 2.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 5.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.0 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis