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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Rxra

Z-value: 0.99

Motif logo

Transcription factors associated with Rxra

Gene Symbol Gene ID Gene Info
ENSRNOG00000009446 retinoid X receptor alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rxrarn6_v1_chr3_+_6211789_6211789-0.399.4e-13Click!

Activity profile of Rxra motif

Sorted Z-values of Rxra motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_113318563 42.02 ENSRNOT00000089230
creatine kinase, mitochondrial 1
chr9_-_92530938 28.10 ENSRNOT00000064875
solute carrier family 16, member 14
chr2_-_225107283 27.95 ENSRNOT00000055711
solute carrier family 44, member 3
chr17_+_23661429 26.49 ENSRNOT00000046523
phosphatase and actin regulator 1
chr4_-_176294997 24.58 ENSRNOT00000015112
ENSRNOT00000051461
ENSRNOT00000000026
ENSRNOT00000039877
ENSRNOT00000049303
kidney specific organic anion transporter
chr10_-_65692016 24.33 ENSRNOT00000085074
ENSRNOT00000038690
solute carrier family 13 member 2
chr18_-_1946840 23.20 ENSRNOT00000041878
abhydrolase domain containing 3
chr1_-_31122093 23.13 ENSRNOT00000016712
SOGA family member 3
chrX_+_14019961 22.93 ENSRNOT00000004785
synaptotagmin-like 5
chr7_+_139685573 22.92 ENSRNOT00000088376
phosphofructokinase, muscle
chr9_-_71852113 22.90 ENSRNOT00000083263
ENSRNOT00000072983

chr3_-_45210474 22.77 ENSRNOT00000091777
coiled-coil domain containing 148
chr4_+_29978739 21.46 ENSRNOT00000011756
protein phosphatase 1, regulatory subunit 9A
chr13_-_80703615 20.27 ENSRNOT00000004599
flavin containing monooxygenase 4
chr16_-_32868680 20.00 ENSRNOT00000015974
ENSRNOT00000082392
aminoadipate aminotransferase
chr4_-_17594598 19.93 ENSRNOT00000008936
semaphorin 3E
chr3_-_52447622 18.57 ENSRNOT00000083552
sodium voltage-gated channel alpha subunit 1
chr4_+_88832178 17.55 ENSRNOT00000088983
ATP-binding cassette, subfamily G (WHITE), member 2
chr8_-_14880644 17.08 ENSRNOT00000015977
FAT atypical cadherin 3
chr7_-_82687130 16.88 ENSRNOT00000006791
transmembrane protein 74
chr7_-_136853957 16.36 ENSRNOT00000008985
neural EGFL like 2
chr15_+_5306459 15.98 ENSRNOT00000092079
CD99 antigen-like protein 2
chr7_+_140788987 15.59 ENSRNOT00000086611
potassium voltage-gated channel subfamily H member 3
chr9_-_69953182 15.40 ENSRNOT00000015852
NADH dehydrogenase (ubiquinone) Fe-S protein 1
chr9_-_83253458 15.04 ENSRNOT00000041689
Eph receptor A4
chr7_+_11356118 14.86 ENSRNOT00000041325
ATCAY, caytaxin
chr19_-_49510901 14.54 ENSRNOT00000082929
ENSRNOT00000079969
hypothetical protein LOC687399
chr19_+_22450030 13.62 ENSRNOT00000021739
neuropilin and tolloid like 2
chr14_-_10395047 13.48 ENSRNOT00000002936
glycerol-3-phosphate acyltransferase 3
chr18_+_45023932 13.22 ENSRNOT00000039379
family with sequence similarity 170, member A
chr1_+_213676954 13.07 ENSRNOT00000050551
NLR family, pyrin domain containing 6
chrX_+_57866709 13.07 ENSRNOT00000040923
protein phosphatase 4 regulatory subunit 3C
chr10_-_47997796 13.05 ENSRNOT00000078422
solute carrier family 5 member 10
chr15_+_675085 12.99 ENSRNOT00000091318
potassium calcium-activated channel subfamily M alpha 1
chr1_+_15620653 12.46 ENSRNOT00000017401
microtubule-associated protein 7
chrX_+_20351486 12.33 ENSRNOT00000093675
ENSRNOT00000047444
WNK lysine deficient protein kinase 3
chr4_+_5644260 11.92 ENSRNOT00000041876
ARP3 actin related protein 3 homolog B
chr1_+_53531947 11.84 ENSRNOT00000077340
t-complex protein 10b
chr2_-_199971965 11.63 ENSRNOT00000087026
phosphodiesterase 4D interacting protein
chr16_+_74810938 11.59 ENSRNOT00000058091
NIMA-related kinase 5
chr7_+_120140460 11.57 ENSRNOT00000040513
ENSRNOT00000073905
pyridoxal phosphatase
chr15_-_45376476 11.27 ENSRNOT00000065838
deleted in lymphocytic leukemia, 7
chr1_-_169344306 11.13 ENSRNOT00000022852
ubiquilin-like
chr11_+_61531571 10.95 ENSRNOT00000093467
ENSRNOT00000002727
ATPase H+ transporting V1 subunit A
chr1_+_97712177 10.60 ENSRNOT00000027745
similar to RIKEN cDNA 4930433I11 gene
chr3_+_69549673 10.58 ENSRNOT00000043974
zinc finger protein 804A
chrX_-_1704033 10.58 ENSRNOT00000051956
ubiquitin specific peptidase 11
chr1_-_250727079 10.56 ENSRNOT00000079942
ENSRNOT00000087588
sphingomyelin synthase 1
chr4_+_114876770 10.52 ENSRNOT00000068102
ENSRNOT00000078175
dynactin subunit 1
chr16_-_10726648 10.26 ENSRNOT00000080635
ENSRNOT00000087150
synuclein, gamma
chr8_+_123126667 10.20 ENSRNOT00000015643
oxysterol binding protein-like 10
chr19_+_58505811 10.19 ENSRNOT00000031717
microtubule-associated protein 10
chr13_+_71110064 10.12 ENSRNOT00000088329
regulator of G-protein signaling 8
chr5_-_171710312 10.08 ENSRNOT00000076044
ENSRNOT00000071280
ENSRNOT00000072059
ENSRNOT00000077015
PR/SET domain 16
chr12_-_18526250 9.97 ENSRNOT00000001791
acetylserotonin O-methyltransferase
chr9_-_65790347 9.79 ENSRNOT00000028506

chr2_-_192780631 9.70 ENSRNOT00000012371
sperm mitochondria-associated cysteine-rich protein
chrX_-_77295426 9.55 ENSRNOT00000090833
TATA-box binding protein associated factor 9b
chr16_+_49462889 9.51 ENSRNOT00000039909
ankyrin repeat domain 37
chrX_+_15035569 9.26 ENSRNOT00000006491
ENSRNOT00000078392
porcupine homolog (Drosophila)
chr11_+_54137639 9.24 ENSRNOT00000066343
leukocyte surface antigen CD47-like
chr10_-_18443934 9.11 ENSRNOT00000059895
ENSRNOT00000080021
RAN binding protein 17
chr1_-_222178725 9.00 ENSRNOT00000028697
estrogen related receptor, alpha
chr4_+_114854458 9.00 ENSRNOT00000013312
hypothetical gene supported by BC079424
chr1_+_187149453 8.98 ENSRNOT00000082738
xylosyltransferase 1
chr5_+_120250616 8.92 ENSRNOT00000070967
adenylate kinase 4
chr1_-_227392054 8.84 ENSRNOT00000054806
membrane-spanning 4-domains, subfamily A, member 13, pseudogene 1
chr14_+_85871597 8.55 ENSRNOT00000079671
ankyrin repeat domain 36
chr1_-_99985422 8.55 ENSRNOT00000025701
kallikrein 1-related peptidase C2
chr11_+_42858478 8.53 ENSRNOT00000002293
ADP-ribosylation factor like GTPase 6
chr17_+_76306585 8.52 ENSRNOT00000065978
dehydrogenase E1 and transketolase domain containing 1
chr3_-_161272460 8.49 ENSRNOT00000020740
acyl-CoA thioesterase 8
chr3_-_160922341 8.42 ENSRNOT00000029206
TP53 target 5
chrY_+_914045 8.41 ENSRNOT00000088593
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr10_+_28449335 8.38 ENSRNOT00000029118
ATPase phospholipid transporting 10B (putative)
chr15_-_25505691 8.23 ENSRNOT00000074488
homeobox protein OTX2-like
chr10_+_46216884 8.18 ENSRNOT00000004448
5',3'-nucleotidase, mitochondrial
chr1_+_79982639 8.13 ENSRNOT00000071916
dystrophia myotonica, WD repeat containing
chr3_+_56056925 8.10 ENSRNOT00000088351
ENSRNOT00000010508
kelch-like family member 23
chr15_+_42960307 7.86 ENSRNOT00000012528
tripartite motif-containing 35
chrX_+_57866406 7.72 ENSRNOT00000076221
protein phosphatase 4 regulatory subunit 3C
chr11_-_70211701 7.71 ENSRNOT00000076114
mucin 13, cell surface associated
chr9_+_4807717 7.70 ENSRNOT00000092159
sulfotransferase 1C2-like
chr16_-_10296341 7.62 ENSRNOT00000083990
zinc finger protein 488
chr10_+_11146359 7.61 ENSRNOT00000006314
presequence translocase associated motor 16 homolog
chr4_+_146455332 7.59 ENSRNOT00000009775
histamine receptor H 1
chr10_+_55169282 7.45 ENSRNOT00000005423
coiled-coil domain containing 42
chr9_-_13311924 7.43 ENSRNOT00000015584
kinesin family member 6
chr7_-_12519154 7.26 ENSRNOT00000093376
ENSRNOT00000077681
glutathione peroxidase 4
chr2_-_90568486 7.25 ENSRNOT00000059380
uncharacterized LOC100910852
chr14_-_78377825 7.09 ENSRNOT00000068104

chr2_-_89498395 6.98 ENSRNOT00000068507

chr6_+_43001948 6.94 ENSRNOT00000007374
hippocalcin-like 1
chr13_-_85622314 6.91 ENSRNOT00000005719
microsomal glutathione S-transferase 3
chr2_-_111793326 6.82 ENSRNOT00000092660
neuroligin 1
chr16_-_70998575 6.82 ENSRNOT00000019935
potassium calcium-activated channel subfamily U member 1
chr8_-_115274165 6.78 ENSRNOT00000056386
IQ domain-containing protein F5-like
chr8_+_19994668 6.72 ENSRNOT00000050608
olfactory receptor 1160
chr2_+_40554146 6.67 ENSRNOT00000015138
phosphodiesterase 4D
chr5_+_57947716 6.52 ENSRNOT00000067657
dynein, axonemal, intermediate chain 1
chr12_-_6078411 6.30 ENSRNOT00000001197
relaxin/insulin-like family peptide receptor 2
chr4_+_168396775 6.25 ENSRNOT00000008645
BLOC-1 related complex subunit 5
chr9_-_81565416 6.24 ENSRNOT00000083582
angio-associated, migratory cell protein
chr3_+_72990358 6.20 ENSRNOT00000091920
olfactory receptor 444
chr14_+_22597103 6.16 ENSRNOT00000048482
UDP glucuronosyltransferase 2 family, polypeptide A1
chr9_-_14906410 6.14 ENSRNOT00000061674
hypothetical protein LOC680955
chr13_-_90589466 6.11 ENSRNOT00000070812
phosphoprotein enriched in astrocytes 15
chr6_-_76535517 6.11 ENSRNOT00000083857
Ral GTPase activating protein catalytic alpha subunit 1
chr10_-_14299167 6.11 ENSRNOT00000042066
mitogen-activated protein kinase 8 interacting protein 3
chr15_-_9086282 6.04 ENSRNOT00000008989
thyroid hormone receptor beta
chr1_+_190072420 5.98 ENSRNOT00000037026
ATP-binding cassette, subfamily A (ABC1), member 15
chr4_-_100783750 5.82 ENSRNOT00000078956
potassium channel modulatory factor 1
chr6_+_129538982 5.81 ENSRNOT00000083626
ENSRNOT00000082522
adenylate kinase 7
chr5_+_129257429 5.80 ENSRNOT00000072396
tetratricopeptide repeat domain 39A
chr3_-_103745236 5.68 ENSRNOT00000006876
NUT midline carcinoma, family member 1
chr11_-_64968437 5.67 ENSRNOT00000059541
COX17 cytochrome c oxidase copper chaperone
chr3_+_75906945 5.63 ENSRNOT00000047110
olfactory receptor 586
chr16_+_12174370 5.60 ENSRNOT00000072045
ral guanine nucleotide dissociation stimulator-like
chr7_-_139394166 5.58 ENSRNOT00000082429
vitamin D (1,25- dihydroxyvitamin D3) receptor
chr14_-_92495894 5.56 ENSRNOT00000064483
cordon-bleu WH2 repeat protein
chr1_-_204805738 5.55 ENSRNOT00000086830
family with sequence similarity 53, member B
chr14_+_11988671 5.53 ENSRNOT00000003207
RasGEF domain family, member 1B
chr17_+_78817529 5.52 ENSRNOT00000021918
meiosis/spermiogenesis associated 1
chr1_-_227359809 5.32 ENSRNOT00000088080
RIKEN cDNA 1700025F22 gene
chr3_+_138770574 5.31 ENSRNOT00000012510
ENSRNOT00000066986
D-tyrosyl-tRNA deacylase 1
chr6_-_142418779 5.25 ENSRNOT00000072280
ENSRNOT00000065808

chr4_-_140503412 5.21 ENSRNOT00000079266

chr3_+_67870111 5.17 ENSRNOT00000012628
nucleoporin 35
chr3_+_161272385 5.12 ENSRNOT00000021052
zinc finger, SWIM-type containing 3
chr12_-_18303041 5.07 ENSRNOT00000032844
similar to Leukosialin precursor (Leucocyte sialoglycoprotein) (Sialophorin) (CD43) (W3/13 antigen)
chr6_+_44230985 5.03 ENSRNOT00000005858
kinase D-interacting substrate 220
chr1_-_99964824 5.03 ENSRNOT00000046377
kallikrein 1-related peptidase C6
chr16_-_12194118 5.00 ENSRNOT00000071517
similar to hypothetical protein 4930474N05
chrX_-_65335987 5.00 ENSRNOT00000047128

chr5_-_156734541 4.93 ENSRNOT00000021036
cytidine deaminase-like
chr1_-_219144610 4.92 ENSRNOT00000023526
NADH:ubiquinone oxidoreductase core subunit S8
chr11_-_1437732 4.86 ENSRNOT00000037345
casein kinase 2, alpha prime interacting protein
chr4_+_87608301 4.77 ENSRNOT00000058702
vomeronasal 1 receptor 71
chr12_-_31629881 4.69 ENSRNOT00000001238
piwi-like RNA-mediated gene silencing 1
chr1_-_221251329 4.61 ENSRNOT00000031678
tigger transposable element derived 3
chr18_+_59096643 4.60 ENSRNOT00000025325
WD repeat domain 7
chr9_-_43276685 4.56 ENSRNOT00000022779
ARP1 actin-related protein 1 homolog B, centractin beta
chr17_-_32158538 4.52 ENSRNOT00000024141
NAD(P)H quinone dehydrogenase 2
chr13_+_83721300 4.47 ENSRNOT00000082677
adenylate cyclase 10 (soluble)
chr5_-_102743417 4.46 ENSRNOT00000067389
basonuclin 2
chr17_+_5281727 4.44 ENSRNOT00000024781
iron-sulfur cluster assembly 1
chr3_+_70327193 4.43 ENSRNOT00000089165
fibrous sheath-interacting protein 2
chr1_+_229066045 4.40 ENSRNOT00000016454
glycine-N-acyltransferase
chr2_-_80667481 4.37 ENSRNOT00000016784
trio Rho guanine nucleotide exchange factor
chr10_+_3227160 4.34 ENSRNOT00000088075
N-terminal asparagine amidase
chr13_-_47440682 4.23 ENSRNOT00000037679
ENSRNOT00000005729
ENSRNOT00000050354
ENSRNOT00000050859
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr3_+_168345152 4.19 ENSRNOT00000017654
docking protein 5
chr9_+_45901741 4.11 ENSRNOT00000059571
neuronal PAS domain protein 2
chr6_+_8669722 4.06 ENSRNOT00000048550
calmodulin-lysine N-methyltransferase
chr20_+_18833481 4.05 ENSRNOT00000080846
BicC family RNA binding protein 1
chr18_+_68983545 4.04 ENSRNOT00000085317
StAR-related lipid transfer domain containing 6
chr3_+_141068023 4.04 ENSRNOT00000036527
kizuna centrosomal protein
chr8_+_117246376 4.02 ENSRNOT00000074493
coiled-coil domain containing 71
chr8_-_83693472 3.97 ENSRNOT00000015947
family with sequence similarity 83, member B
chr15_+_39945095 3.91 ENSRNOT00000016826
shisa family member 2
chr10_+_91830654 3.84 ENSRNOT00000005176
wingless-type MMTV integration site family, member 3
chr1_+_86914137 3.84 ENSRNOT00000027006
F-box protein 17
chr1_+_171592797 3.74 ENSRNOT00000026607
synaptotagmin 9
chr1_-_169598835 3.74 ENSRNOT00000072996
olfactory receptor 156
chr1_-_215310013 3.73 ENSRNOT00000054858

chr6_+_78567970 3.72 ENSRNOT00000032743
tetratricopeptide repeat domain 6
chr7_-_62162453 3.71 ENSRNOT00000010720
cullin-associated and neddylation-dissociated 1
chr16_-_12538117 3.67 ENSRNOT00000046081

chr7_-_144960527 3.65 ENSRNOT00000086554
zinc finger protein 385A
chr1_+_220243473 3.62 ENSRNOT00000084650
ENSRNOT00000027091
mitochondrial ribosomal protein L11
chr19_+_24456976 3.52 ENSRNOT00000004900
uncoupling protein 1
chr6_-_26051229 3.46 ENSRNOT00000005855
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr3_+_171213936 3.41 ENSRNOT00000031586
phosphoenolpyruvate carboxykinase 1
chr6_-_122239614 3.39 ENSRNOT00000005015
galactosylceramidase
chr5_+_59491096 3.38 ENSRNOT00000019737
ENSRNOT00000036366
ENSRNOT00000083068
clathrin, light chain A
chr8_+_41336340 3.36 ENSRNOT00000072049
olfactory receptor 1225
chr2_+_86914989 3.34 ENSRNOT00000085164
ENSRNOT00000081966
zinc finger protein 457-like
chr4_+_88184956 3.32 ENSRNOT00000077129
vomeronasal 1 receptor 83
chr14_-_21898284 3.25 ENSRNOT00000036314
proline rich 27
chr14_+_85230648 3.19 ENSRNOT00000089866
adaptor-related protein complex 1, beta 1 subunit
chr16_+_13050305 3.11 ENSRNOT00000077388

chr2_+_149899836 3.02 ENSRNOT00000086481
similar to hypothetical protein C130079G13
chr3_-_77883067 3.01 ENSRNOT00000087979
olfactory receptor 677
chrX_+_45637415 2.99 ENSRNOT00000050544
similar to ferritin heavy polypeptide-like 17
chr1_+_221236773 2.97 ENSRNOT00000051979
solute carrier family 25, member 45
chr1_+_226091774 2.89 ENSRNOT00000027693
fatty acid desaturase 3
chr2_+_196304492 2.82 ENSRNOT00000028640
LysM domain containing 1
chr17_+_8558827 2.82 ENSRNOT00000016187
interleukin 9
chr9_+_49647257 2.75 ENSRNOT00000021899
mitochondrial ribosomal protein S9
chr7_-_12346475 2.69 ENSRNOT00000060708
melanoma associated antigen (mutated) 1
chr12_+_6403940 2.66 ENSRNOT00000083484
beta 3-glucosyltransferase
chr1_-_238376841 2.59 ENSRNOT00000076393
transmembrane channel-like 1
chr1_-_8878136 2.58 ENSRNOT00000064836
ENSRNOT00000075850
vesicle trafficking 1
chr1_+_41065716 2.57 ENSRNOT00000035962
coiled-coil domain containing 170
chr12_-_30566032 2.55 ENSRNOT00000093378
glioblastoma amplified sequence
chr8_-_43796224 2.50 ENSRNOT00000084315
olfactory receptor 1330
chr1_+_264741911 2.50 ENSRNOT00000019956
semaphorin 4G
chr3_-_153454160 2.50 ENSRNOT00000010298
growth hormone releasing hormone
chr15_-_28446785 2.42 ENSRNOT00000015439
olfactory receptor 1638
chr11_-_43992598 2.32 ENSRNOT00000002260
claudin domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Rxra

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 20.0 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
6.1 24.6 GO:0051958 methotrexate transport(GO:0051958)
5.9 17.6 GO:0019389 glucuronoside metabolic process(GO:0019389)
5.7 22.9 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
5.0 15.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
5.0 14.9 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
4.5 13.6 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
4.3 13.0 GO:0060082 eye blink reflex(GO:0060082)
4.1 12.3 GO:2000682 positive regulation of rubidium ion transport(GO:2000682) positive regulation of rubidium ion transmembrane transporter activity(GO:2000688)
3.9 11.6 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
3.6 21.5 GO:1900272 negative regulation of long-term synaptic potentiation(GO:1900272)
3.3 10.0 GO:0030186 melatonin metabolic process(GO:0030186)
2.8 8.5 GO:1903445 protein transport from ciliary membrane to plasma membrane(GO:1903445)
2.7 8.2 GO:0046078 dUMP metabolic process(GO:0046078)
2.5 7.6 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
2.2 15.6 GO:0000160 phosphorelay signal transduction system(GO:0000160)
2.2 6.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
2.1 10.5 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
1.9 5.6 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
1.7 6.8 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
1.6 9.4 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
1.5 10.6 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
1.5 10.2 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
1.4 18.6 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
1.4 5.7 GO:1904959 regulation of cytochrome-c oxidase activity(GO:1904959)
1.4 9.7 GO:0007341 penetration of zona pellucida(GO:0007341)
1.3 10.3 GO:0071464 cellular response to hydrostatic pressure(GO:0071464)
1.2 3.7 GO:0010265 SCF complex assembly(GO:0010265)
1.1 10.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
1.1 5.5 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
1.0 12.5 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
1.0 6.0 GO:0008050 female courtship behavior(GO:0008050)
1.0 8.8 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.9 3.7 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.9 3.4 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.8 10.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.8 8.5 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.7 9.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.7 13.1 GO:0070255 regulation of mucus secretion(GO:0070255)
0.7 18.2 GO:0010842 retina layer formation(GO:0010842)
0.7 6.8 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.7 4.7 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.6 4.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.6 3.0 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.6 12.5 GO:0033327 Leydig cell differentiation(GO:0033327)
0.6 8.7 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.6 1.7 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
0.6 3.4 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.6 13.9 GO:0003351 epithelial cilium movement(GO:0003351)
0.6 23.2 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.5 4.2 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.5 19.9 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953) semaphorin-plexin signaling pathway(GO:0071526)
0.5 2.6 GO:0060005 vestibular reflex(GO:0060005)
0.5 4.1 GO:0051775 response to redox state(GO:0051775)
0.5 6.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.5 7.7 GO:0051923 sulfation(GO:0051923)
0.5 8.9 GO:0046033 AMP metabolic process(GO:0046033)
0.5 26.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.5 7.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.5 1.9 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.4 2.2 GO:1903181 myoblast fate commitment(GO:0048625) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.4 42.0 GO:0032091 negative regulation of protein binding(GO:0032091)
0.4 2.6 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.4 2.5 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.4 2.1 GO:2000327 positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.4 7.9 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.4 6.1 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.4 6.0 GO:0042737 drug catabolic process(GO:0042737)
0.4 5.0 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.4 3.9 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.4 3.5 GO:0002024 diet induced thermogenesis(GO:0002024)
0.3 4.2 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.3 2.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.3 10.9 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.3 7.6 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.3 8.4 GO:0045332 phospholipid translocation(GO:0045332)
0.3 2.1 GO:0035338 fatty acid elongation, monounsaturated fatty acid(GO:0034625) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.3 8.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.3 4.9 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.3 5.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.3 5.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607) nuclear pore organization(GO:0006999)
0.3 26.5 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.3 9.0 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.3 16.2 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.3 4.5 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.3 9.5 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.3 2.8 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.2 3.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 6.3 GO:0001556 oocyte maturation(GO:0001556)
0.2 5.3 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 8.2 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.2 6.7 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.2 4.5 GO:0043586 tongue development(GO:0043586)
0.2 4.4 GO:0006544 glycine metabolic process(GO:0006544)
0.2 11.6 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)
0.2 6.1 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.2 7.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.2 18.7 GO:0016579 protein deubiquitination(GO:0016579)
0.1 1.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 3.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 1.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 27.7 GO:0006814 sodium ion transport(GO:0006814)
0.1 9.3 GO:0006497 protein lipidation(GO:0006497)
0.1 1.9 GO:0034453 microtubule anchoring(GO:0034453)
0.1 6.2 GO:0072384 organelle transport along microtubule(GO:0072384)
0.1 7.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 0.2 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 15.8 GO:0016236 macroautophagy(GO:0016236)
0.1 6.2 GO:0014909 smooth muscle cell migration(GO:0014909)
0.1 0.9 GO:1901673 regulation of mitotic spindle assembly(GO:1901673) negative regulation of cilium assembly(GO:1902018)
0.1 0.7 GO:0001845 phagolysosome assembly(GO:0001845) equilibrioception(GO:0050957)
0.1 14.1 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.1 3.5 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.1 12.6 GO:0007286 spermatid development(GO:0007286)
0.1 1.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.8 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 8.4 GO:0006413 translational initiation(GO:0006413)
0.1 6.8 GO:0050821 protein stabilization(GO:0050821)
0.1 1.9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 4.1 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1 1.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.3 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 3.8 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.7 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 4.0 GO:0007051 spindle organization(GO:0007051)
0.0 2.0 GO:1990748 cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 5.5 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 23.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.7 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.0 3.3 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 22.9 GO:0005945 6-phosphofructokinase complex(GO:0005945)
5.4 21.5 GO:1990761 growth cone lamellipodium(GO:1990761)
1.9 7.6 GO:0001405 presequence translocase-associated import motor(GO:0001405)
1.9 15.1 GO:0005869 dynactin complex(GO:0005869)
1.7 8.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
1.6 6.2 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
1.3 13.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
1.2 10.6 GO:0000138 Golgi trans cisterna(GO:0000138)
1.1 6.5 GO:0036157 outer dynein arm(GO:0036157)
1.1 8.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.9 18.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.9 11.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.9 10.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.8 5.6 GO:0001651 dense fibrillar component(GO:0001651)
0.8 5.6 GO:1990357 terminal web(GO:1990357)
0.7 9.5 GO:0000124 SAGA complex(GO:0000124)
0.7 13.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.7 3.5 GO:0070552 BRISC complex(GO:0070552)
0.7 10.2 GO:0097431 mitotic spindle pole(GO:0097431) mitotic spindle midzone(GO:1990023)
0.6 1.7 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.5 4.7 GO:0097433 dense body(GO:0097433)
0.5 5.2 GO:0044615 nuclear pore central transport channel(GO:0044613) nuclear pore nuclear basket(GO:0044615)
0.4 8.5 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.4 2.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.4 6.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.4 20.3 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.4 3.4 GO:0071439 clathrin complex(GO:0071439)
0.4 15.0 GO:0044295 axonal growth cone(GO:0044295)
0.3 7.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.3 15.2 GO:0045171 intercellular bridge(GO:0045171)
0.3 9.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 57.0 GO:0043204 perikaryon(GO:0043204)
0.3 0.8 GO:0031308 intrinsic component of nuclear outer membrane(GO:0031308) integral component of nuclear outer membrane(GO:0031309)
0.3 3.7 GO:0031045 dense core granule(GO:0031045)
0.3 3.2 GO:0061702 inflammasome complex(GO:0061702)
0.2 0.7 GO:1990879 CST complex(GO:1990879)
0.2 6.1 GO:0030673 axolemma(GO:0030673)
0.2 10.1 GO:0016235 aggresome(GO:0016235)
0.2 2.6 GO:0032426 stereocilium tip(GO:0032426)
0.2 6.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 9.1 GO:0005643 nuclear pore(GO:0005643)
0.1 13.6 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 29.1 GO:0070382 exocytic vesicle(GO:0070382)
0.1 3.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.7 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 8.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 5.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 5.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 10.3 GO:0043679 axon terminus(GO:0043679)
0.1 5.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 11.0 GO:0005923 bicellular tight junction(GO:0005923)
0.1 22.9 GO:0016324 apical plasma membrane(GO:0016324)
0.1 1.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 36.7 GO:0030425 dendrite(GO:0030425)
0.1 7.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 3.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 3.6 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.1 17.0 GO:0045202 synapse(GO:0045202)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 5.0 GO:0005770 late endosome(GO:0005770)
0.0 0.9 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 9.0 GO:0005929 cilium(GO:0005929)
0.0 13.3 GO:0005813 centrosome(GO:0005813)
0.0 43.3 GO:0005739 mitochondrion(GO:0005739)
0.0 6.0 GO:0000790 nuclear chromatin(GO:0000790)
0.0 6.3 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 4.1 GO:0000139 Golgi membrane(GO:0000139)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 24.6 GO:0015350 methotrexate transporter activity(GO:0015350)
6.0 42.0 GO:0004111 creatine kinase activity(GO:0004111)
5.7 22.9 GO:0003872 6-phosphofructokinase activity(GO:0003872)
5.0 20.0 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
5.0 19.8 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
3.9 23.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
3.9 11.6 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
3.0 15.0 GO:0042731 PH domain binding(GO:0042731)
3.0 9.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
2.8 8.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
2.2 15.6 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
2.1 10.6 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
2.0 17.6 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
1.8 47.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
1.7 20.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
1.5 19.9 GO:0030215 semaphorin receptor binding(GO:0030215)
1.5 7.6 GO:0004969 histamine receptor activity(GO:0004969)
1.5 5.8 GO:0004127 cytidylate kinase activity(GO:0004127)
1.4 5.6 GO:0038181 bile acid receptor activity(GO:0038181) vitamin D response element binding(GO:0070644)
1.3 13.0 GO:0005412 glucose:sodium symporter activity(GO:0005412)
1.3 7.8 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
1.2 9.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
1.2 13.1 GO:0005000 vasopressin receptor activity(GO:0005000)
1.2 4.7 GO:0034584 piRNA binding(GO:0034584)
1.1 9.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
1.0 12.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
1.0 8.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.9 5.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.9 7.3 GO:0008430 selenium binding(GO:0008430)
0.9 3.5 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.9 6.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.8 2.5 GO:0031770 growth hormone-releasing hormone receptor binding(GO:0031770)
0.8 19.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.7 4.4 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.7 8.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.7 6.0 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.6 4.5 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.6 17.7 GO:0031402 sodium ion binding(GO:0031402)
0.6 5.7 GO:0016531 metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531)
0.6 6.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.5 10.9 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.5 10.0 GO:0008171 O-methyltransferase activity(GO:0008171)
0.5 4.0 GO:0004630 phospholipase D activity(GO:0004630)
0.5 6.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.5 8.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.5 8.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.5 6.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.4 33.2 GO:0030276 clathrin binding(GO:0030276)
0.4 14.9 GO:0050699 WW domain binding(GO:0050699)
0.4 4.2 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.4 10.5 GO:0070840 dynein complex binding(GO:0070840)
0.4 3.0 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.4 1.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.4 5.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.3 6.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.3 11.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.3 7.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.3 2.6 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.3 9.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.3 13.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.3 5.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.3 3.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.3 10.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 16.4 GO:0005080 protein kinase C binding(GO:0005080)
0.2 10.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 2.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 4.9 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 3.8 GO:0048018 receptor agonist activity(GO:0048018)
0.2 2.2 GO:0050897 cobalt ion binding(GO:0050897)
0.2 1.0 GO:0045322 unmethylated CpG binding(GO:0045322)
0.2 5.6 GO:0003785 actin monomer binding(GO:0003785)
0.2 0.7 GO:0004977 melanocortin receptor activity(GO:0004977)
0.2 4.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.2 3.2 GO:0008199 ferric iron binding(GO:0008199)
0.1 4.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 10.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 8.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 10.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 3.7 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 2.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 7.4 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 0.8 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 13.5 GO:0003774 motor activity(GO:0003774)
0.1 3.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 7.3 GO:0005496 steroid binding(GO:0005496)
0.1 0.9 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 1.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 4.4 GO:0031491 nucleosome binding(GO:0031491)
0.1 7.4 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 2.1 GO:0005109 frizzled binding(GO:0005109)
0.1 6.2 GO:0051082 unfolded protein binding(GO:0051082)
0.1 10.6 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.1 1.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 11.5 GO:0008017 microtubule binding(GO:0008017)
0.1 6.9 GO:0030165 PDZ domain binding(GO:0030165)
0.1 3.6 GO:0019843 rRNA binding(GO:0019843)
0.1 7.3 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 2.2 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 16.5 GO:0005549 odorant binding(GO:0005549)
0.0 3.6 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 5.1 GO:0015293 symporter activity(GO:0015293)
0.0 1.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 7.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.5 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 2.8 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 7.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.5 GO:0002039 p53 binding(GO:0002039)
0.0 2.8 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 5.5 GO:0005525 GTP binding(GO:0005525)
0.0 6.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.5 GO:0042162 telomeric DNA binding(GO:0042162)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 19.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.4 15.0 PID EPHA FWDPATHWAY EPHA forward signaling
0.3 10.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 6.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.2 4.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 17.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 4.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 7.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 5.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.2 4.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 3.4 PID ARF 3PATHWAY Arf1 pathway
0.1 13.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 6.1 PID P73PATHWAY p73 transcription factor network
0.1 16.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 3.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 8.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.8 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.8 PID SHP2 PATHWAY SHP2 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 21.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
2.2 20.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
1.7 24.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
1.1 27.9 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.9 8.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.7 27.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.7 11.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.6 8.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.5 7.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.4 10.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.4 3.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.4 3.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.3 10.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.3 6.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 15.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.3 13.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.3 6.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 6.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 16.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 5.0 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.2 6.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 4.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 7.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 15.1 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.2 15.0 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.2 5.2 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.2 4.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 8.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 2.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 4.4 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 4.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 2.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 2.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 1.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 4.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.9 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 3.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.9 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex