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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Runx3

Z-value: 0.42

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Transcription factors associated with Runx3

Gene Symbol Gene ID Gene Info
Runx3
ENSRNOG00000054217 runt-related transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Runx3rn6_v1_chr5_+_153507093_1535070930.164.8e-03Click!

Activity profile of Runx3 motif

Sorted Z-values of Runx3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_62948720 7.79 ENSRNOT00000075476
Islr
immunoglobulin superfamily containing leucine-rich repeat
chr7_-_126913585 6.95 ENSRNOT00000036025
Celsr1
cadherin, EGF LAG seven-pass G-type receptor 1
chr4_-_170763916 6.77 ENSRNOT00000071512
Hist1h4m
histone cluster 1, H4m
chr1_+_198528635 6.67 ENSRNOT00000022765
LOC308990
hypothetical protein LOC308990
chr4_-_170092848 6.44 ENSRNOT00000072147
Hist2h4
histone cluster 2, H4
chr2_+_225827504 6.41 ENSRNOT00000018343
Gclm
glutamate cysteine ligase, modifier subunit
chr12_-_22417980 6.07 ENSRNOT00000072208
Ephb4
EPH receptor B4
chr4_-_170117325 5.14 ENSRNOT00000074198
LOC100912564
histone H4-like
chr4_-_170145262 5.02 ENSRNOT00000074526
Hist1h4b
histone cluster 1, H4b
chr17_-_44815995 4.90 ENSRNOT00000091201
RGD1562378
histone H4 variant H4-v.1
chr17_+_43673294 4.55 ENSRNOT00000074109
Hist2h4a
histone cluster 2, H4
chrX_+_68891227 4.45 ENSRNOT00000009635
Efnb1
ephrin B1
chr5_+_105230580 4.40 ENSRNOT00000010056
Acer2
alkaline ceramidase 2
chr5_+_149077412 4.38 ENSRNOT00000014666
Matn1
matrilin 1, cartilage matrix protein
chr9_-_61418679 4.13 ENSRNOT00000078800
Ankrd44
ankyrin repeat domain 44
chr4_+_22898527 3.95 ENSRNOT00000072455
ENSRNOT00000076123
Dbf4
DBF4 zinc finger
chr4_+_119680112 3.93 ENSRNOT00000013282
Gp9
glycoprotein IX (platelet)
chr1_+_224800252 3.91 ENSRNOT00000024488
Slc22a8
solute carrier family 22 member 8
chr17_-_27665266 3.69 ENSRNOT00000060218
Rreb1
ras responsive element binding protein 1
chr10_-_88144468 3.66 ENSRNOT00000084619
Ka11
type I keratin KA11
chr13_+_89386023 3.65 ENSRNOT00000086223
Fcgr3a
Fc fragment of IgG receptor IIIa
chr1_+_214203861 3.31 ENSRNOT00000023219
Rassf7
Ras association domain family member 7
chr19_+_43251539 3.29 ENSRNOT00000024793
Ddx19a
DEAD-box helicase 19A
chr4_+_49056010 3.18 ENSRNOT00000038566
Cped1
cadherin-like and PC-esterase domain containing 1
chr7_-_120077612 3.16 ENSRNOT00000011750
Lgals2
galectin 2
chr6_+_107245820 3.06 ENSRNOT00000012757
Papln
papilin, proteoglycan-like sulfated glycoprotein
chr10_-_87928251 2.79 ENSRNOT00000064120
Krtap17-1
keratin associated protein 17-1
chr5_-_161981441 2.78 ENSRNOT00000020316
Pdpn
podoplanin
chr2_-_210934749 2.77 ENSRNOT00000026710
Gnai3
G protein subunit alpha i3
chr3_-_13978224 2.64 ENSRNOT00000025528
Phf19
PHD finger protein 19
chr15_+_47293699 2.52 ENSRNOT00000016503
Sox7
SRY box 7
chr13_+_92249759 2.32 ENSRNOT00000089352
Olr1596
olfactory receptor 1596
chr10_-_88144625 2.21 ENSRNOT00000086209
Ka11
type I keratin KA11
chr1_-_72468738 2.11 ENSRNOT00000029136
Zfp628
zinc finger protein 628
chr10_-_110701137 2.09 ENSRNOT00000074193
Znf750
zinc finger protein 750
chr10_+_59533480 2.04 ENSRNOT00000087723
Atp2a3
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr13_-_92988137 2.01 ENSRNOT00000004803
Grem2
gremlin 2, DAN family BMP antagonist
chr3_+_45683993 1.93 ENSRNOT00000038983
Tanc1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr1_-_142114634 1.85 ENSRNOT00000029471
Rccd1
RCC1 domain containing 1
chrX_+_78259409 1.84 ENSRNOT00000049779
RGD1560455
similar to RIKEN cDNA A630033H20 gene
chr17_+_53956203 1.83 ENSRNOT00000022483
Ggps1
geranylgeranyl diphosphate synthase 1
chr5_+_18963937 1.78 ENSRNOT00000082188
AABR07047089.1

chr2_+_210034095 1.71 ENSRNOT00000024473
Lamtor5
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr20_-_5244386 1.57 ENSRNOT00000070886
RT1-DMa
RT1 class II, locus DMa
chr7_+_132857628 1.39 ENSRNOT00000005438
Lrrk2
leucine-rich repeat kinase 2
chr4_+_147832136 1.33 ENSRNOT00000064603
Rho
rhodopsin
chr14_-_86117578 1.31 ENSRNOT00000019288
Pold2
DNA polymerase delta 2, accessory subunit
chr2_-_181900856 1.28 ENSRNOT00000082156
Lrat
lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
chr8_-_7426611 1.26 ENSRNOT00000031492
Arhgap42
Rho GTPase activating protein 42
chr4_+_100209951 1.25 ENSRNOT00000015807
LOC691113
hypothetical protein LOC691113
chr1_-_221087449 1.18 ENSRNOT00000016987
Fam89b
family with sequence similarity 89, member B
chr6_-_145777767 1.06 ENSRNOT00000046799
Rpl32
ribosomal protein L32
chr4_+_6827429 1.06 ENSRNOT00000071737
Rheb
Ras homolog enriched in brain
chr8_-_116872215 1.02 ENSRNOT00000045410
Apeh
acylaminoacyl-peptide hydrolase
chr2_-_193063357 0.97 ENSRNOT00000072995
AABR07012317.2

chr20_-_3386048 0.96 ENSRNOT00000089550
ENSRNOT00000065025
Dhx16
DEAH-box helicase 16
chr14_+_108412152 0.95 ENSRNOT00000083707
Pus10
pseudouridylate synthase 10
chr2_-_198120041 0.94 ENSRNOT00000079621
ENSRNOT00000028747
Plekho1
pleckstrin homology domain containing O1
chr16_-_69195097 0.90 ENSRNOT00000018973
Erlin2
ER lipid raft associated 2
chr1_+_69789110 0.90 ENSRNOT00000088123
NEWGENE_1305281
hippocampus abundant transcript 1
chr5_-_151898022 0.90 ENSRNOT00000000133
Pigv
phosphatidylinositol glycan anchor biosynthesis, class V
chr5_-_2882668 0.88 ENSRNOT00000049741
Terf1
telomeric repeat binding factor 1
chr10_+_63677396 0.87 ENSRNOT00000005100
Slc43a2
solute carrier family 43 member 2
chr4_+_115473811 0.87 ENSRNOT00000042875
Nagk
N-acetylglucosamine kinase
chr9_-_43139870 0.85 ENSRNOT00000021956
Sema4c
semaphorin 4C
chr6_+_108831108 0.83 ENSRNOT00000038594
LOC103692678
U6 snRNA-associated Sm-like protein LSm5 pseudogene
chr2_-_9023104 0.82 ENSRNOT00000039652
Adgrv1
adhesion G protein-coupled receptor V1
chr7_+_14589520 0.80 ENSRNOT00000060210
Cyp4f37
cytochrome P450, family 4, subfamily f, polypeptide 37
chr1_-_77830399 0.69 ENSRNOT00000052231
LOC100360449
ribosomal protein L9-like
chr10_+_11046221 0.67 ENSRNOT00000005109
Nmral1
NmrA like redox sensor 1
chr15_+_30812576 0.65 ENSRNOT00000060420
AABR07017768.1

chr20_+_4966817 0.64 ENSRNOT00000081527
ENSRNOT00000081265
Lsm2
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr2_+_116372519 0.61 ENSRNOT00000031730
Lrrc34
leucine rich repeat containing 34
chr15_-_29976615 0.60 ENSRNOT00000060396
AABR07017676.1

chr10_-_15667955 0.58 ENSRNOT00000085746
ENSRNOT00000027940
Mpg
N-methylpurine-DNA glycosylase
chr14_+_78939903 0.58 ENSRNOT00000078562
ENSRNOT00000088221
Man2b2
Mrfap1
mannosidase, alpha, class 2B, member 2
Morf4 family associated protein 1
chr10_-_61744976 0.58 ENSRNOT00000079926
ENSRNOT00000092314
ENSRNOT00000034298
Sgsm2
small G protein signaling modulator 2
chr20_+_4967194 0.52 ENSRNOT00000070846
Lsm2
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr3_-_10161989 0.51 ENSRNOT00000012312
Exosc2
exosome component 2
chr1_+_69788609 0.45 ENSRNOT00000075340
NEWGENE_1305281
hippocampus abundant transcript 1
chrX_+_157353577 0.42 ENSRNOT00000090596
Haus7
HAUS augmin-like complex, subunit 7
chr10_+_11046024 0.39 ENSRNOT00000084850
Nmral1
NmrA like redox sensor 1
chr13_+_110372164 0.38 ENSRNOT00000049634
RGD1560186
similar to ribosomal protein L37
chr7_+_2504695 0.37 ENSRNOT00000003965
Atp5b
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr7_+_2827247 0.35 ENSRNOT00000090689
Rnf41
ring finger protein 41
chr6_-_115352681 0.34 ENSRNOT00000005873
Gtf2a1
general transcription factor 2A subunit 1
chr5_+_57738321 0.33 ENSRNOT00000063849
Ubap1
ubiquitin-associated protein 1
chr10_+_48240330 0.30 ENSRNOT00000057798
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr5_-_25721072 0.30 ENSRNOT00000021839
Tmem67
transmembrane protein 67
chr2_-_219693629 0.26 ENSRNOT00000020907
Mfsd14a
major facilitator superfamily domain containing 14A
chr9_+_10995198 0.21 ENSRNOT00000089071
Ubxn6
UBX domain protein 6
chr10_-_85435016 0.21 ENSRNOT00000079921
4933428G20Rik
RIKEN cDNA 4933428G20 gene
chr12_+_2228670 0.19 ENSRNOT00000001327
Trappc5
trafficking protein particle complex 5
chr10_-_14373334 0.12 ENSRNOT00000022050
Cramp1
cramped chromatin regulator homolog 1
chrX_+_63343546 0.11 ENSRNOT00000076315
Klhl15
kelch-like family member 15
chr1_-_235813030 0.05 ENSRNOT00000014800
Vps13a
vacuolar protein sorting 13A
chr10_+_48240127 0.03 ENSRNOT00000080682
Specc1
sperm antigen with calponin homology and coiled-coil domains 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Runx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.9 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
1.9 32.8 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
1.6 6.4 GO:0097069 cellular response to thyroxine stimulus(GO:0097069)
1.5 6.1 GO:2000523 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
1.5 4.4 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
1.3 3.9 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.8 3.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.7 2.0 GO:0060300 regulation of cytokine activity(GO:0060300)
0.6 4.4 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.6 1.8 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.5 1.4 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499) regulation of peroxidase activity(GO:2000468)
0.4 1.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.4 1.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.3 2.8 GO:0015884 folic acid transport(GO:0015884)
0.3 2.6 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.3 0.9 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.3 1.6 GO:0002399 MHC class II protein complex assembly(GO:0002399) peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.2 3.6 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094) Fc-epsilon receptor signaling pathway(GO:0038095)
0.2 0.9 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 4.4 GO:0031295 T cell costimulation(GO:0031295)
0.2 0.6 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.2 0.9 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.2 0.5 GO:0071031 nuclear mRNA surveillance of mRNA 3'-end processing(GO:0071031) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription(GO:0071049)
0.2 1.3 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.2 1.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.2 0.9 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 1.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.1 0.8 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.4 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 1.9 GO:0097062 dendritic spine maintenance(GO:0097062)
0.1 2.8 GO:0046039 GTP metabolic process(GO:0046039)
0.1 1.3 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.1 0.9 GO:0051451 myoblast migration(GO:0051451)
0.1 1.7 GO:0061462 protein localization to lysosome(GO:0061462)
0.1 1.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.6 GO:0006013 mannose metabolic process(GO:0006013)
0.0 3.3 GO:0010043 response to zinc ion(GO:0010043)
0.0 2.5 GO:0001706 endoderm formation(GO:0001706)
0.0 0.8 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.3 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 1.0 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.3 GO:0010826 negative regulation of centrosome duplication(GO:0010826) photoreceptor cell outer segment organization(GO:0035845) negative regulation of centrosome cycle(GO:0046606)
0.0 0.9 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.9 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 1.1 GO:0097421 liver regeneration(GO:0097421)
0.0 3.3 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 0.6 GO:0006284 base-excision repair(GO:0006284)
0.0 3.1 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 32.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 1.4 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.3 1.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 1.7 GO:0071986 Ragulator complex(GO:0071986)
0.2 1.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.2 0.9 GO:0031501 mannosyltransferase complex(GO:0031501)
0.2 0.9 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2 2.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.8 GO:0002142 stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696)
0.1 2.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 4.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 2.8 GO:0042588 zymogen granule(GO:0042588)
0.1 1.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.9 GO:0070187 telosome(GO:0070187)
0.1 2.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.4 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 1.3 GO:0005771 multivesicular body(GO:0005771)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 3.1 GO:0005604 basement membrane(GO:0005604)
0.0 3.7 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 4.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 3.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 5.3 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 3.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.0 GO:0005681 spliceosomal complex(GO:0005681)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.4 GO:0017040 ceramidase activity(GO:0017040)
0.7 3.6 GO:0019770 IgG receptor activity(GO:0019770)
0.5 3.9 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.5 1.4 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.4 2.8 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.4 3.2 GO:0016936 galactoside binding(GO:0016936)
0.4 1.8 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.3 2.8 GO:0008517 folic acid transporter activity(GO:0008517)
0.3 6.8 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.3 6.1 GO:0005003 ephrin receptor activity(GO:0005003)
0.3 0.9 GO:0009384 N-acylmannosamine kinase activity(GO:0009384)
0.2 2.0 GO:0036122 BMP binding(GO:0036122)
0.2 34.2 GO:0042393 histone binding(GO:0042393)
0.1 1.3 GO:0009881 photoreceptor activity(GO:0009881)
0.1 0.9 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 4.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.3 GO:0019841 retinol binding(GO:0019841)
0.1 1.0 GO:0008242 omega peptidase activity(GO:0008242)
0.1 2.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.4 GO:0043532 angiostatin binding(GO:0043532)
0.1 1.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 4.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 1.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 3.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 1.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.6 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 0.9 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.6 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 3.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.4 GO:0031996 thioesterase binding(GO:0031996)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.5 GO:0004532 exoribonuclease activity(GO:0004532)
0.0 0.9 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.8 GO:0017022 myosin binding(GO:0017022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.2 3.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 2.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 2.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 3.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 4.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 4.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 10.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.4 3.9 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.3 3.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 6.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 1.3 REACTOME OPSINS Genes involved in Opsins
0.2 2.8 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 4.0 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 4.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 3.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.6 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.3 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation