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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Rora

Z-value: 0.56

Motif logo

Transcription factors associated with Rora

Gene Symbol Gene ID Gene Info
ENSRNOG00000027145 RAR-related orphan receptor A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rorarn6_v1_chr8_+_75516904_755169040.141.3e-02Click!

Activity profile of Rora motif

Sorted Z-values of Rora motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_101687855 19.87 ENSRNOT00000028546
ENSRNOT00000091597
D-box binding PAR bZIP transcription factor
chr19_-_10653800 12.48 ENSRNOT00000022128
C-X3-C motif chemokine ligand 1
chr3_-_113525864 10.53 ENSRNOT00000046659
FERM domain containing 5
chr8_-_82533689 10.16 ENSRNOT00000014124
tropomodulin 2
chr3_+_113319456 10.09 ENSRNOT00000051354
creatine kinase, mitochondrial 1
chr7_-_81592206 9.97 ENSRNOT00000007979
angiopoietin 1
chr10_-_86688730 9.25 ENSRNOT00000055333
nuclear receptor subfamily 1, group D, member 1
chr6_-_136145837 8.76 ENSRNOT00000015122
creatine kinase B
chr18_-_1946840 8.48 ENSRNOT00000041878
abhydrolase domain containing 3
chr13_-_86451002 7.91 ENSRNOT00000043004
ENSRNOT00000027996
PBX homeobox 1
chr12_+_47024442 7.77 ENSRNOT00000001545
cytochrome c oxidase subunit 6A1
chr14_-_114583122 7.69 ENSRNOT00000084595
spectrin, beta, non-erythrocytic 1
chr5_-_147412705 7.50 ENSRNOT00000010688
similar to mKIAA1522 protein
chr8_-_47404010 7.38 ENSRNOT00000038647
transmembrane protein 136
chr13_+_34610684 7.08 ENSRNOT00000093019
ENSRNOT00000003280
transcription factor CP2-like 1
chr9_+_61692154 7.04 ENSRNOT00000082300
heat shock protein family E member 1
chr3_+_8534440 6.91 ENSRNOT00000045827
ENSRNOT00000082672
spectrin, alpha, non-erythrocytic 1
chr1_+_199555722 6.64 ENSRNOT00000054983
integrin subunit alpha X
chr18_+_2416871 6.52 ENSRNOT00000081399
GATA binding protein 6
chr2_-_210282352 6.44 ENSRNOT00000075653
solute carrier family 6 member 17
chr3_+_151126591 6.35 ENSRNOT00000025859
myosin heavy chain 7B
chr18_+_2416552 6.30 ENSRNOT00000030726
GATA binding protein 6
chr19_+_568287 6.18 ENSRNOT00000016419
cadherin 16
chr9_-_61690956 6.13 ENSRNOT00000066589
heat shock protein family D member 1
chr10_+_55712043 6.12 ENSRNOT00000010141
arachidonate lipoxygenase 3
chr1_+_197659187 6.10 ENSRNOT00000082228
serine/threonine-protein kinase SBK1
chr5_-_157268903 6.09 ENSRNOT00000022716
phospholipase A2, group V
chr7_+_53630621 5.99 ENSRNOT00000067011
ENSRNOT00000080598
cysteine and glycine-rich protein 2
chr8_+_71167305 5.69 ENSRNOT00000021337
RNA binding protein with multiple splicing 2
chr1_+_72882806 5.52 ENSRNOT00000024640
troponin I3, cardiac type
chr3_-_146396299 5.39 ENSRNOT00000040188
ENSRNOT00000008931
adipocyte plasma membrane associated protein
chr6_+_106496992 5.38 ENSRNOT00000086136
ENSRNOT00000058181
regulator of G-protein signaling 6
chr12_+_40018937 5.32 ENSRNOT00000001697
cut-like homeobox 2
chr1_-_170404056 5.04 ENSRNOT00000024402
amyloid beta precursor protein binding family B member 1
chrX_-_135342996 4.97 ENSRNOT00000084848
ENSRNOT00000008503
apoptosis inducing factor, mitochondria associated 1
chr2_-_56679955 4.90 ENSRNOT00000016722
EGF-like, fibronectin type III and laminin G domains
chr12_+_47698947 4.86 ENSRNOT00000001586
transient receptor potential cation channel, subfamily V, member 4
chr5_+_147069616 4.77 ENSRNOT00000072908
tripartite motif-containing 62
chr9_+_2202511 4.62 ENSRNOT00000017556
SATB homeobox 1
chr1_-_124803363 4.53 ENSRNOT00000066380
Kruppel-like factor 13
chr20_-_14545772 4.44 ENSRNOT00000001766
BCR, RhoGEF and GTPase activating protein
chr8_+_33239139 4.20 ENSRNOT00000011589
Rho GTPase activating protein 32
chr3_-_81304181 4.16 ENSRNOT00000079746
mitogen-activated protein kinase 8 interacting protein 1
chr7_+_143810892 4.15 ENSRNOT00000016240
zinc finger protein 740
chr1_-_265542276 4.13 ENSRNOT00000065172
meningioma expressed antigen 5 (hyaluronidase)
chr6_-_36819821 4.08 ENSRNOT00000006499
potassium voltage-gated channel, modifier subfamily S, member 3
chr18_-_3555711 3.92 ENSRNOT00000029274
transmembrane protein 241
chr2_+_239415046 3.89 ENSRNOT00000072196
CXXC finger protein 4
chrX_+_68774699 3.78 ENSRNOT00000081662
StAR-related lipid transfer domain containing 8
chr1_+_198682230 3.62 ENSRNOT00000023995
zinc finger protein 48
chr11_+_61531571 3.47 ENSRNOT00000093467
ENSRNOT00000002727
ATPase H+ transporting V1 subunit A
chr5_+_150754021 3.44 ENSRNOT00000017687
platelet-activating factor receptor
chr10_+_29165577 3.31 ENSRNOT00000078415
cyclin J-like
chr7_+_121311024 3.29 ENSRNOT00000092260
ENSRNOT00000023066
ENSRNOT00000081377
synaptogyrin 1
chr4_+_157836912 3.29 ENSRNOT00000067271
sodium channel epithelial 1 alpha subunit
chr14_-_106393670 3.24 ENSRNOT00000011429
malate dehydrogenase 1
chr8_+_48443767 3.20 ENSRNOT00000010127
C1q and tumor necrosis factor related protein 5
chr14_+_88549947 3.16 ENSRNOT00000086177
heterogeneous nuclear ribonucleoprotein C
chr9_+_10471742 3.15 ENSRNOT00000072276
scaffold attachment factor B2
chr4_-_77706994 3.15 ENSRNOT00000038517
zinc finger protein 777
chr7_+_123102493 3.15 ENSRNOT00000038612
aconitase 2
chrX_+_54734385 3.11 ENSRNOT00000005023
nuclear receptor subfamily 0, group B, member 1
chr3_+_154905141 3.10 ENSRNOT00000088748
ENSRNOT00000020556
Ral GTPase activating protein non-catalytic beta subunit
chr6_-_3355339 3.07 ENSRNOT00000084602
mitogen-activated protein kinase kinase kinase kinase 3
chr18_+_30856847 3.03 ENSRNOT00000027019

chr7_-_12424367 2.97 ENSRNOT00000060698
midnolin
chr5_+_74766636 2.94 ENSRNOT00000030913

chr19_-_42920344 2.92 ENSRNOT00000019408
ENSRNOT00000068594
zinc finger homeobox 3
chr3_-_150156839 2.88 ENSRNOT00000036217
elongation factor 1-alpha 1 pseudogene
chr8_+_39878955 2.85 ENSRNOT00000060300
roundabout homolog 4-like
chr10_-_90240509 2.82 ENSRNOT00000028407
ataxin 7-like 3
chr3_+_125320680 2.79 ENSRNOT00000028891
hypothetical protein LOC681292
chr3_+_156727642 2.72 ENSRNOT00000078909
phospholipase C, gamma 1
chr14_+_81362618 2.71 ENSRNOT00000017386
major facilitator superfamily domain containing 10
chr3_+_123731539 2.61 ENSRNOT00000051064
cell division cycle 25B
chr1_-_53087474 2.59 ENSRNOT00000017302
C-C motif chemokine receptor 6
chr20_+_3351303 2.59 ENSRNOT00000080419
ENSRNOT00000001065
ENSRNOT00000086503
alpha tubulin acetyltransferase 1
chr4_+_145413230 2.58 ENSRNOT00000056508
interleukin 17 receptor E
chr1_-_70003582 2.57 ENSRNOT00000055721
ubiquitin specific peptidase 29
chr5_-_164348713 2.57 ENSRNOT00000087044
similar to casein kinase 1, gamma 3 isoform 2
chr17_-_15094805 2.57 ENSRNOT00000044073
F-box and WD-40 domain protein 17
chr3_+_155297566 2.51 ENSRNOT00000021435
ENSRNOT00000084866
DEAH-box helicase 35
chr7_-_70480724 2.46 ENSRNOT00000090057
deltex E3 ubiquitin ligase 3
chr1_-_187779675 2.44 ENSRNOT00000024648
ADP-ribosylation factor like GTPase 6 interacting protein 1
chr10_-_88356538 2.43 ENSRNOT00000022430
5'-nucleotidase, cytosolic IIIB
chr6_+_12362813 2.40 ENSRNOT00000022370
stonin 1
chr11_+_61531416 2.35 ENSRNOT00000093263
ATPase H+ transporting V1 subunit A
chr16_-_69242028 2.35 ENSRNOT00000019002
zinc finger protein 703
chr10_-_59888198 2.35 ENSRNOT00000093482
ENSRNOT00000049311
ENSRNOT00000093230
aspartoacylase
chr3_-_93789617 2.32 ENSRNOT00000078616
cell cycle associated protein 1
chr1_-_221041401 2.31 ENSRNOT00000064136
pecanex homolog 3 (Drosophila)
chr10_-_896938 2.31 ENSRNOT00000086392
nudE neurodevelopment protein 1
chrX_-_74847379 2.31 ENSRNOT00000067009
ring finger protein, LIM domain interacting
chr6_-_76552559 2.25 ENSRNOT00000065230
Ral GTPase activating protein catalytic alpha subunit 1
chr16_-_32753278 2.24 ENSRNOT00000015759
microfibrillar-associated protein 3-like
chr20_-_4817146 2.23 ENSRNOT00000080174
DExD-box helicase 39B
chr1_-_134870255 2.20 ENSRNOT00000055829
chromodomain helicase DNA binding protein 2
chr3_-_133894569 2.20 ENSRNOT00000084221

chr2_+_28460068 2.19 ENSRNOT00000066819
forkhead box D1
chr8_+_36125999 2.17 ENSRNOT00000013036
ENSRNOT00000088046
kin of IRRE like 3 (Drosophila)
chr2_-_111793326 2.17 ENSRNOT00000092660
neuroligin 1
chr1_+_221773254 2.11 ENSRNOT00000028646
RAS guanyl releasing protein 2
chr1_-_73732118 2.10 ENSRNOT00000077964
leukocyte receptor cluster member 8
chr7_+_120755516 2.08 ENSRNOT00000056169
KDEL endoplasmic reticulum protein retention receptor 3
chr1_+_85460888 2.08 ENSRNOT00000093384
SPT5 homolog, DSIF elongation factor subunit
chr8_+_39305128 2.06 ENSRNOT00000008285
fasciculation and elongation protein zeta 1
chr3_+_147609095 2.03 ENSRNOT00000041456
sulfiredoxin 1
chr20_-_13657943 2.03 ENSRNOT00000032290
pre-B lymphocyte 3
chr5_-_101138427 2.00 ENSRNOT00000058615
Fras1 related extracellular matrix 1
chr16_-_81243757 1.99 ENSRNOT00000024677
growth arrest specific 6
chr2_-_113345577 1.99 ENSRNOT00000034096
fibronectin type III domain containing 3B
chr8_+_48094673 1.98 ENSRNOT00000008614
nectin cell adhesion molecule 1
chr3_-_60765645 1.97 ENSRNOT00000050513
activating transcription factor 2
chr2_-_238803024 1.97 ENSRNOT00000046775
tet methylcytosine dioxygenase 2
chr10_-_5260608 1.92 ENSRNOT00000003572
class II, major histocompatibility complex, transactivator
chr3_+_113257688 1.91 ENSRNOT00000019320
microtubule-associated protein 1A
chr20_-_5618254 1.87 ENSRNOT00000092326
ENSRNOT00000000576
BCL2-antagonist/killer 1
chr10_-_82963919 1.86 ENSRNOT00000005807
distal-less homeobox 4
chr8_-_116965396 1.86 ENSRNOT00000042528
bassoon (presynaptic cytomatrix protein)
chr13_-_78521911 1.85 ENSRNOT00000087506
RAB GTPase activating protein 1-like
chr9_-_93404883 1.78 ENSRNOT00000025024
neuromedin U receptor 1
chr1_+_80954858 1.76 ENSRNOT00000030440
zinc finger protein 112
chr1_-_91588609 1.72 ENSRNOT00000050931
small nuclear ribonucleoprotein polypeptide G
chr10_-_88357025 1.69 ENSRNOT00000080006
5'-nucleotidase, cytosolic IIIB
chr3_+_14304591 1.68 ENSRNOT00000007776
centriolin
chr15_-_37030240 1.62 ENSRNOT00000028219
ENSRNOT00000088037
paraspeckle component 1
chr15_-_86142672 1.61 ENSRNOT00000057830
COMM domain containing 6
chr20_+_29831314 1.54 ENSRNOT00000000696
prosaposin
chr2_+_38230757 1.50 ENSRNOT00000048598
similar to 60S ribosomal protein L23a
chr1_-_213973163 1.50 ENSRNOT00000024867
cell cycle exit and neuronal differentiation protein 1-like
chr7_+_73273985 1.43 ENSRNOT00000077730
POP1 homolog, ribonuclease P/MRP subunit
chr14_+_76732650 1.42 ENSRNOT00000088197
cytokine-dependent hematopoietic cell linker
chr5_+_138300107 1.40 ENSRNOT00000047151
claudin 19
chr4_+_152449270 1.39 ENSRNOT00000076733
RAD52 homolog, DNA repair protein
chr14_-_44375804 1.36 ENSRNOT00000042825
ribosomal protein P2-like
chr10_+_61685241 1.35 ENSRNOT00000092606
MAX network transcriptional repressor
chr8_+_114867062 1.30 ENSRNOT00000074771
WD repeat domain 82
chr8_+_29453643 1.30 ENSRNOT00000090643
opioid binding protein/cell adhesion molecule-like
chr17_+_86066833 1.24 ENSRNOT00000022661
methionine sulfoxide reductase B2
chr1_+_87066289 1.23 ENSRNOT00000027645
calpain 12
chr1_-_78968329 1.22 ENSRNOT00000023078
protein phosphatase 5, catalytic subunit
chr5_+_144701949 1.20 ENSRNOT00000015618
proteasome subunit beta 2
chr1_+_61374379 1.19 ENSRNOT00000015343
zinc finger protein 53
chr8_-_133128290 1.19 ENSRNOT00000008783
chemokine (C-C motif) receptor 1-like 1
chr12_-_30566032 1.17 ENSRNOT00000093378
glioblastoma amplified sequence
chr10_+_59000397 1.14 ENSRNOT00000021134
MYB binding protein 1a
chr20_+_28572242 1.09 ENSRNOT00000072485
SH3 domain containing ring finger 3
chr18_-_31430973 1.08 ENSRNOT00000026065
protocadherin 12
chr1_+_224882439 1.00 ENSRNOT00000024785
cholinergic receptor, muscarinic 1
chr1_-_64175099 1.00 ENSRNOT00000091288
NADH:ubiquinone oxidoreductase subunit A3
chr10_-_104748003 0.98 ENSRNOT00000042372
ENSRNOT00000046754
acyl-CoA oxidase 1
chr4_-_145487426 0.94 ENSRNOT00000013488
ER membrane protein complex subunit 3
chr3_-_153952108 0.94 ENSRNOT00000050465
adipogenin
chr10_-_15155412 0.91 ENSRNOT00000026536
hydroxyacylglutathione hydrolase-like
chr10_+_82032656 0.87 ENSRNOT00000067751
ankyrin repeat domain 40
chr17_-_90315492 0.86 ENSRNOT00000070807
G protein subunit gamma 4
chr18_+_70733872 0.85 ENSRNOT00000067018
acetyl-CoA acyltransferase 2
chr6_-_143195143 0.85 ENSRNOT00000081337

chr17_+_45247776 0.83 ENSRNOT00000081063
ENSRNOT00000080655
zinc finger with KRAB and SCAN domains 3
chr10_-_14247886 0.75 ENSRNOT00000020504
nucleotide binding protein 2
chr13_-_71282802 0.75 ENSRNOT00000025544
regulator of G-protein signaling like 2 homolog (mouse)
chr10_+_110893232 0.74 ENSRNOT00000072190
meteorin-like, glial cell differentiation regulator
chr6_-_135049728 0.74 ENSRNOT00000009556
heat shock protein 90 alpha family class A member 1
chr12_-_46718355 0.72 ENSRNOT00000030031
RAB35, member RAS oncogene family
chr20_+_9586075 0.70 ENSRNOT00000001527
ENSRNOT00000079509
glucagon-like peptide 1 receptor
chr8_+_104106740 0.66 ENSRNOT00000015015
transcription factor Dp-2
chr6_-_107678156 0.62 ENSRNOT00000014158
ELM2 and Myb/SANT domain containing 1
chr10_-_85517683 0.61 ENSRNOT00000016070
SRC kinase signaling inhibitor 1
chr3_+_117853999 0.59 ENSRNOT00000042949
40S ribosomal protein S14-like
chr1_-_219853329 0.58 ENSRNOT00000026169
leucine rich repeat and fibronectin type III domain containing 4
chr4_+_82637411 0.57 ENSRNOT00000048225
LRRGT00062
chr13_-_85622314 0.57 ENSRNOT00000005719
microsomal glutathione S-transferase 3
chr7_+_98432024 0.53 ENSRNOT00000091077
fer-1-like family member 6
chr12_+_30441055 0.53 ENSRNOT00000081099

chr4_+_170958196 0.52 ENSRNOT00000007905
phosphodiesterase 6H
chrX_-_78911601 0.52 ENSRNOT00000003188
similar to RIKEN cDNA 2610002M06
chr1_-_62191818 0.50 ENSRNOT00000033187

chr3_+_73366155 0.49 ENSRNOT00000044979
olfactory receptor 473
chr8_-_48449311 0.42 ENSRNOT00000010134
ring finger protein 26
chr8_+_59164572 0.41 ENSRNOT00000015102
isocitrate dehydrogenase 3 (NAD+) alpha
chr1_-_170927957 0.38 ENSRNOT00000049686
olfactory receptor 218
chr1_-_126211439 0.36 ENSRNOT00000014988
tight junction protein 1
chr6_-_143195445 0.35 ENSRNOT00000078672

chr18_-_63185510 0.34 ENSRNOT00000024632
AFG3 like matrix AAA peptidase subunit 2
chr14_-_105069565 0.34 ENSRNOT00000067365

chr10_+_29123273 0.30 ENSRNOT00000005171
cyclin J-like
chr3_+_94549180 0.27 ENSRNOT00000016318
cleavage stimulation factor subunit 3
chr5_-_59149625 0.23 ENSRNOT00000040641
ENSRNOT00000084216
sperm associated antigen 8
chr7_-_114590119 0.21 ENSRNOT00000079599
protein tyrosine kinase 2
chr2_+_252305874 0.17 ENSRNOT00000020972
chitobiase
chr18_+_29587901 0.12 ENSRNOT00000085470
WD repeat domain 55
chr19_+_25095089 0.11 ENSRNOT00000041717
protein kinase cAMP-activated catalytic subunit alpha
chrX_-_113474164 0.08 ENSRNOT00000046804
guanylate cyclase 2F
chr3_-_60813869 0.08 ENSRNOT00000058234
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr16_+_1979191 0.06 ENSRNOT00000014382
peptidylprolyl isomerase F
chr8_-_40122450 0.04 ENSRNOT00000039729
transforming growth factor beta regulator 1
chr3_+_21313227 0.01 ENSRNOT00000036335
similar to olfactory receptor Olr1374

Network of associatons between targets according to the STRING database.

First level regulatory network of Rora

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 12.8 GO:0007493 endodermal cell fate determination(GO:0007493) negative regulation of transforming growth factor beta2 production(GO:0032912)
3.3 10.0 GO:0048014 Tie signaling pathway(GO:0048014)
3.1 9.2 GO:0060086 circadian temperature homeostasis(GO:0060086)
2.1 6.4 GO:0015820 leucine transport(GO:0015820)
2.1 12.5 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
2.0 6.1 GO:0002840 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) protein import into mitochondrial intermembrane space(GO:0045041)
2.0 6.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
1.6 4.9 GO:0072566 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) regulation of macrophage inflammatory protein 1 alpha production(GO:0071640) chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
1.5 4.4 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
1.3 10.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
1.2 6.1 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
1.1 3.4 GO:0043313 response to symbiotic bacterium(GO:0009609) regulation of neutrophil degranulation(GO:0043313)
1.0 4.1 GO:0060051 negative regulation of protein glycosylation(GO:0060051)
1.0 9.0 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
1.0 5.0 GO:1904045 cellular response to aldosterone(GO:1904045)
0.9 2.6 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.8 2.4 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.8 3.9 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.8 3.1 GO:0060178 regulation of exocyst localization(GO:0060178)
0.8 2.3 GO:1900095 random inactivation of X chromosome(GO:0060816) regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.7 2.8 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.7 7.7 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.7 2.7 GO:0042891 antibiotic transport(GO:0042891)
0.7 2.0 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.6 2.6 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.6 4.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.6 7.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.6 3.0 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.6 3.6 GO:0006102 isocitrate metabolic process(GO:0006102)
0.6 7.1 GO:0007028 cytoplasm organization(GO:0007028)
0.5 2.2 GO:0072076 nephrogenic mesenchyme development(GO:0072076) pattern specification involved in metanephros development(GO:0072268)
0.5 2.2 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.5 2.2 GO:0099545 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.5 3.2 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.5 2.0 GO:0097018 cellular response to vitamin K(GO:0071307) renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) negative regulation of dendritic cell apoptotic process(GO:2000669)
0.5 2.3 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.5 2.7 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.4 5.7 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.4 7.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.4 7.0 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.4 5.3 GO:0007614 short-term memory(GO:0007614)
0.4 4.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.4 7.9 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.4 2.6 GO:0007144 female meiosis I(GO:0007144)
0.4 1.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.3 5.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.3 2.0 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.3 4.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.3 1.0 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.3 4.5 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.3 1.9 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.3 2.2 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.3 1.9 GO:0002339 B cell selection(GO:0002339) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.3 1.9 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.3 2.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.3 2.0 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.3 3.2 GO:0006108 malate metabolic process(GO:0006108)
0.3 1.5 GO:0046836 glycolipid transport(GO:0046836)
0.2 0.7 GO:0061741 vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741)
0.2 1.4 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.2 2.1 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.2 2.0 GO:1902414 protein localization to cell junction(GO:1902414)
0.2 2.4 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.2 3.1 GO:0030238 male sex determination(GO:0030238)
0.2 8.5 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.2 1.0 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.2 4.8 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.2 0.9 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 6.9 GO:0051693 actin filament capping(GO:0051693)
0.2 3.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 5.9 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.2 2.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.2 0.9 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.2 1.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 1.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 2.8 GO:0016578 histone deubiquitination(GO:0016578)
0.1 6.6 GO:0050798 activated T cell proliferation(GO:0050798)
0.1 0.7 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 2.2 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 3.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 2.4 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 5.0 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.1 1.4 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 2.0 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 3.2 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.1 9.7 GO:0032091 negative regulation of protein binding(GO:0032091)
0.1 0.7 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 0.7 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.1 0.4 GO:0071000 response to magnetism(GO:0071000)
0.1 19.9 GO:0001889 liver development(GO:0001889)
0.1 0.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 2.3 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 3.3 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.1 1.3 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 0.8 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.1 1.2 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.1 1.8 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.1 1.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 1.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 1.9 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 4.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.5 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.0 6.2 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.6 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 1.7 GO:0060976 coronary vasculature development(GO:0060976)
0.0 3.9 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 2.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.7 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 2.3 GO:0045445 myoblast differentiation(GO:0045445)
0.0 0.5 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 9.6 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 1.4 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 1.3 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 1.3 GO:0070206 protein trimerization(GO:0070206)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 2.4 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 1.5 GO:0021549 cerebellum development(GO:0021549)
0.0 0.0 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 14.6 GO:0008091 spectrin(GO:0008091) cuticular plate(GO:0032437)
1.4 4.2 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
1.4 5.5 GO:1990584 cardiac Troponin complex(GO:1990584)
1.3 5.0 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
1.2 6.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
1.1 6.3 GO:0097512 cardiac myofibril(GO:0097512)
1.1 3.2 GO:1990826 nucleoplasmic periphery of the nuclear pore complex(GO:1990826)
0.6 2.6 GO:0097427 microtubule bundle(GO:0097427)
0.6 1.9 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.5 2.1 GO:0032044 DSIF complex(GO:0032044)
0.5 2.4 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.5 5.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.5 3.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.5 1.4 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.4 6.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.3 4.0 GO:0005687 U4 snRNP(GO:0005687)
0.3 3.1 GO:0042788 polysomal ribosome(GO:0042788)
0.3 1.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.2 2.0 GO:0032584 growth cone membrane(GO:0032584)
0.2 4.9 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.6 GO:0042382 paraspeckles(GO:0042382)
0.2 3.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 2.8 GO:0000124 SAGA complex(GO:0000124)
0.2 6.6 GO:0008305 integrin complex(GO:0008305)
0.2 6.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.4 GO:0045242 mitochondrial isocitrate dehydrogenase complex (NAD+)(GO:0005962) isocitrate dehydrogenase complex (NAD+)(GO:0045242)
0.1 3.3 GO:0034706 sodium channel complex(GO:0034706)
0.1 2.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.2 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.3 GO:0005745 m-AAA complex(GO:0005745)
0.1 1.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 9.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 10.0 GO:0005902 microvillus(GO:0005902)
0.1 21.2 GO:0043209 myelin sheath(GO:0043209)
0.1 0.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 4.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 2.7 GO:0008180 COP9 signalosome(GO:0008180)
0.1 11.1 GO:0001650 fibrillar center(GO:0001650)
0.1 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 2.0 GO:0035861 site of double-strand break(GO:0035861)
0.1 1.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 6.5 GO:0016605 PML body(GO:0016605)
0.1 3.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.1 4.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 1.0 GO:0032279 asymmetric synapse(GO:0032279)
0.1 2.2 GO:0043198 dendritic shaft(GO:0043198)
0.1 2.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 9.6 GO:0043197 dendritic spine(GO:0043197)
0.0 1.2 GO:0005839 proteasome core complex(GO:0005839)
0.0 18.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.7 GO:0031526 brush border membrane(GO:0031526)
0.0 2.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 8.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 2.5 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 2.6 GO:0000922 spindle pole(GO:0000922)
0.0 2.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.9 GO:0030426 growth cone(GO:0030426)
0.0 0.7 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 8.1 GO:0098794 postsynapse(GO:0098794)
0.0 2.0 GO:0005604 basement membrane(GO:0005604)
0.0 3.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 4.4 GO:0005925 focal adhesion(GO:0005925)
0.0 0.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 18.8 GO:0004111 creatine kinase activity(GO:0004111)
1.7 3.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
1.4 8.5 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
1.4 5.5 GO:0030172 troponin C binding(GO:0030172)
1.2 6.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
1.0 3.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.9 2.7 GO:0042895 antibiotic transporter activity(GO:0042895)
0.8 4.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.8 3.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.8 2.4 GO:0019807 aspartoacylase activity(GO:0019807)
0.8 3.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.8 5.4 GO:0004064 arylesterase activity(GO:0004064)
0.7 6.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.7 10.2 GO:0005523 tropomyosin binding(GO:0005523)
0.7 3.9 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.6 11.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.6 5.0 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.5 4.9 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.5 3.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.5 3.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.5 2.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.5 1.4 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.4 2.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.4 3.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.4 12.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.4 2.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.4 2.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.4 3.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.3 12.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.3 2.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 2.7 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.3 2.2 GO:0017070 U6 snRNA binding(GO:0017070) U4 snRNA binding(GO:0030621)
0.3 5.8 GO:0048156 tau protein binding(GO:0048156)
0.2 4.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 6.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.2 6.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 2.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 6.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 1.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 1.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.2 1.0 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.2 1.5 GO:0004565 beta-galactosidase activity(GO:0004565)
0.2 1.7 GO:1990446 U1 snRNP binding(GO:1990446)
0.2 4.0 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.2 0.9 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 0.7 GO:0004967 glucagon receptor activity(GO:0004967)
0.2 11.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.2 2.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 14.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 6.9 GO:0030507 spectrin binding(GO:0030507)
0.1 0.9 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.1 1.9 GO:0051400 BH domain binding(GO:0051400)
0.1 0.4 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 33.4 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 2.4 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 21.2 GO:0005096 GTPase activator activity(GO:0005096)
0.1 2.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 6.4 GO:0051087 chaperone binding(GO:0051087)
0.1 14.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 5.1 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.1 2.8 GO:0001047 core promoter binding(GO:0001047)
0.1 1.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 1.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 2.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.4 GO:0071253 connexin binding(GO:0071253)
0.0 1.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.9 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 2.5 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 1.8 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.5 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0 1.9 GO:0005518 collagen binding(GO:0005518)
0.0 2.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 2.8 GO:0003774 motor activity(GO:0003774)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.5 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 2.5 GO:0008017 microtubule binding(GO:0008017)
0.0 2.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.3 2.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3 6.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 6.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.2 2.7 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 3.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 6.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.2 12.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.2 10.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.2 5.0 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 4.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 10.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 6.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 7.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 7.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 3.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 3.1 PID TNF PATHWAY TNF receptor signaling pathway
0.1 11.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 3.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 4.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 2.1 PID RAS PATHWAY Regulation of Ras family activation
0.1 3.2 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 2.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 5.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 29.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.6 2.6 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.6 10.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.6 16.8 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.4 8.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.4 6.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.2 11.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 5.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.2 3.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 2.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 1.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 5.6 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1 2.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 12.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 2.1 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1 4.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 1.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 6.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 6.6 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 3.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 0.7 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 1.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 10.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 2.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.0 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 5.4 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 2.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 3.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 2.6 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 2.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import