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GSE53960: rat RNA-Seq transcriptomic Bodymap
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Results for Rhox11
Z-value: 0.83
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Transcription factors associated with Rhox11
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Rhox11 | rn6_v1_chrX_+_124228270_124228270 | -0.02 | 7.1e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr10_+_72272248 Show fit | 37.40 |
ENSRNOT00000003908
|
carbonic anhydrase 4 |
|
| chr18_+_70548607 Show fit | 32.45 |
ENSRNOT00000085318
|
myosin Vb |
|
| chr4_+_168832910 Show fit | 25.14 |
ENSRNOT00000011134
|
G protein-coupled receptor, class C, group 5, member A |
|
| chr5_+_119727839 Show fit | 18.17 |
ENSRNOT00000014354
|
cache domain containing 1 |
|
| chr14_+_109533792 Show fit | 16.72 |
ENSRNOT00000067690
|
ankyrin repeat domain-containing protein 29-like |
|
| chr5_-_138462864 Show fit | 16.58 |
ENSRNOT00000011325
|
coiled-coil domain containing 30 |
|
| chr20_+_46044892 Show fit | 15.51 |
ENSRNOT00000057187
|
adenylate kinase 9 |
|
| chr9_-_30321323 Show fit | 15.28 |
ENSRNOT00000018234
|
family with sequence similarity 135, member A |
|
| chr13_+_47454591 Show fit | 14.83 |
ENSRNOT00000005791
|
similar to specifically androgen-regulated protein |
|
| chr6_-_49324450 Show fit | 14.65 |
ENSRNOT00000066904
|
syntrophin, gamma 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Rhox11
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 37.4 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 5.4 | 32.5 | GO:0032439 | endosome localization(GO:0032439) |
| 2.1 | 25.1 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 5.2 | 15.5 | GO:0009216 | purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216) dGDP metabolic process(GO:0046066) |
| 0.6 | 14.5 | GO:0010842 | retina layer formation(GO:0010842) |
| 3.5 | 14.0 | GO:0072086 | specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268) |
| 0.3 | 13.5 | GO:0021522 | spinal cord motor neuron differentiation(GO:0021522) |
| 0.2 | 13.1 | GO:0050775 | positive regulation of dendrite morphogenesis(GO:0050775) |
| 0.0 | 12.7 | GO:0043523 | regulation of neuron apoptotic process(GO:0043523) |
| 0.3 | 12.6 | GO:0017144 | drug metabolic process(GO:0017144) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 37.4 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.0 | 32.7 | GO:0036477 | somatodendritic compartment(GO:0036477) |
| 3.2 | 32.5 | GO:0045179 | apical cortex(GO:0045179) |
| 0.0 | 18.6 | GO:0005730 | nucleolus(GO:0005730) |
| 0.0 | 18.0 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.2 | 13.7 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 1.1 | 13.1 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 2.3 | 11.6 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 0.8 | 11.1 | GO:0032426 | stereocilium tip(GO:0032426) |
| 2.6 | 10.2 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 38.9 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.8 | 35.0 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.0 | 25.5 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.1 | 25.1 | GO:0045296 | cadherin binding(GO:0045296) |
| 5.2 | 15.5 | GO:0050145 | nucleoside phosphate kinase activity(GO:0050145) |
| 0.1 | 15.3 | GO:0052689 | carboxylic ester hydrolase activity(GO:0052689) |
| 2.1 | 14.6 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.5 | 13.1 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 1.1 | 12.6 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.1 | 11.8 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 11.3 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.2 | 10.6 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 10.3 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.1 | 10.2 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.4 | 9.7 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 9.4 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 5.1 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 4.8 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.1 | 4.7 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.1 | 4.6 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 32.5 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.3 | 12.6 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.2 | 10.6 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.1 | 10.3 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 1.1 | 10.2 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.1 | 9.9 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.7 | 9.7 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 8.0 | REACTOME PHASE II CONJUGATION | Genes involved in Phase II conjugation |
| 0.4 | 7.6 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS | Genes involved in Synthesis of bile acids and bile salts |
| 0.4 | 6.8 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |