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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Rarb

Z-value: 0.43

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Transcription factors associated with Rarb

Gene Symbol Gene ID Gene Info
Rarb
ENSRNOG00000024061 retinoic acid receptor, beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rarbrn6_v1_chr15_+_10120206_101202060.491.7e-20Click!

Activity profile of Rarb motif

Sorted Z-values of Rarb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_48360131 25.03 ENSRNOT00000051927
ENSRNOT00000023116
Slc22a2
solute carrier family 22 member 2
chr14_+_22375955 17.97 ENSRNOT00000063915
ENSRNOT00000034784
Ugt2b37
UDP-glucuronosyltransferase 2 family, member 37
chr6_+_33176778 13.26 ENSRNOT00000046811
ENSRNOT00000007371
Apob
apolipoprotein B
chr4_-_82203154 12.43 ENSRNOT00000086210
LOC100912608
homeobox protein Hox-A10-like
chr16_-_20460959 10.88 ENSRNOT00000026457
Pde4c
phosphodiesterase 4C
chr1_+_264741911 10.20 ENSRNOT00000019956
Sema4g
semaphorin 4G
chr18_+_61261418 8.64 ENSRNOT00000064250
Zfp532
zinc finger protein 532
chr14_+_22806132 7.90 ENSRNOT00000002728
Ugt2b10
UDP glucuronosyltransferase 2 family, polypeptide B10
chr17_-_78499881 4.37 ENSRNOT00000079260
Fam107b
family with sequence similarity 107, member B
chr9_+_30419001 4.28 ENSRNOT00000018116
Col9a1
collagen type IX alpha 1 chain
chr14_+_22597103 3.53 ENSRNOT00000048482
Ugt2a1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr10_+_70627401 1.78 ENSRNOT00000076897
Rasl10b
RAS-like, family 10, member B
chr9_+_97355924 1.68 ENSRNOT00000026558
Ackr3
atypical chemokine receptor 3
chr19_-_55389256 1.15 ENSRNOT00000064180
Aprt
adenine phosphoribosyl transferase
chr2_-_250923744 0.94 ENSRNOT00000084996
Clca1
chloride channel accessory 1
chr1_-_22570303 0.73 ENSRNOT00000035539
Taar3
trace amine-associated receptor 3
chr18_+_30885789 0.62 ENSRNOT00000044434
Pcdhga9
protocadherin gamma subfamily A, 9
chr8_+_40488792 0.30 ENSRNOT00000076868
Olr1204
olfactory receptor 1204
chr1_-_245817809 0.27 ENSRNOT00000080607
AABR07006672.1

chr10_+_55555089 0.19 ENSRNOT00000006597
Slc25a35
solute carrier family 25, member 35
chr13_+_110511668 0.16 ENSRNOT00000006235
Nek2
NIMA-related kinase 2
chr1_+_247110216 0.12 ENSRNOT00000016000
Cdc37l1
cell division cycle 37-like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Rarb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 25.0 GO:0015871 choline transport(GO:0015871)
1.9 13.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.6 1.8 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.4 10.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.4 1.1 GO:0044209 AMP salvage(GO:0044209)
0.3 3.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.2 4.3 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 1.7 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.2 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 4.4 GO:0007605 sensory perception of sound(GO:0007605)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 13.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
1.4 4.3 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 25.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.9 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 1.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 18.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 10.9 GO:0005929 cilium(GO:0005929)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.3 25.0 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
2.2 13.3 GO:0035473 lipase binding(GO:0035473)
0.9 29.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.6 10.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.4 1.1 GO:0002060 purine nucleobase binding(GO:0002060)
0.2 1.7 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.7 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 12.4 GO:0043565 sequence-specific DNA binding(GO:0043565)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 13.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 4.3 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 10.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 25.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.8 13.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.6 11.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.4 10.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 4.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage