ISMARA results: Ptf1a

Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation

Downloads

Results for Ptf1a

Z-value: 0.89

Motif logo

Transcription factors associated with Ptf1a

Gene Symbol	Gene ID	Gene Info
Ptf1a NCBI RGD Ensembl	ENSRNOG00000016902	pancreas specific transcription factor, 1a

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Ptf1a	rn6_v1_chr17_+_86199623_86199623	0.49	6.8e-21	Click!

Activity profile of Ptf1a motif

Sorted Z-values of Ptf1a motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr19_-_43911057 Show fit	59.92	ENSRNOT00000026017	Ctrb1 NCBI RGD Ensembl Show fit	chymotrypsinogen B1
chr4_+_70755795 Show fit	46.48	ENSRNOT00000043527	LOC683849 NCBI RGD Ensembl Show fit	similar to Anionic trypsin II precursor (Pretrypsinogen II)
chr4_+_70689737 Show fit	44.54	ENSRNOT00000018852	Prss2 NCBI RGD Ensembl Show fit	protease, serine, 2
chr4_+_70614524 Show fit	36.92	ENSRNOT00000041100	Prss3 NCBI RGD Ensembl Show fit	protease, serine 3
chr7_+_70807867 Show fit	33.90	ENSRNOT00000010639	Stac3 NCBI RGD Ensembl Show fit	SH3 and cysteine rich domain 3
chr1_-_255376833 Show fit	31.06	ENSRNOT00000024941	Ppp1r3c NCBI RGD Ensembl Show fit	protein phosphatase 1, regulatory subunit 3C
chr10_-_95934345 Show fit	30.16	ENSRNOT00000004349	Cacng1 NCBI RGD Ensembl Show fit	calcium voltage-gated channel auxiliary subunit gamma 1
chr4_-_70747226 Show fit	29.38	ENSRNOT00000044960	LOC102554637 NCBI RGD Ensembl Show fit	anionic trypsin-2-like
chr2_-_173668555 Show fit	29.26	ENSRNOT00000013452	Serpini2 NCBI RGD Ensembl Show fit	serpin family I member 2
chr4_-_70628470 Show fit	26.15	ENSRNOT00000029319	Try5 NCBI RGD Ensembl Show fit	trypsin 5

Showing 1 to 10 of 154 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Ptf1a

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	187.9	GO:0007586	digestion(GO:0007586)
0.8	33.9	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
2.6	31.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.8	30.2	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
2.0	25.7	GO:0001778	plasma membrane repair(GO:0001778)
0.0	22.9	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
2.9	17.3	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
5.0	14.9	GO:0060988	lipid tube assembly(GO:0060988)
0.2	14.8	GO:0061077	chaperone-mediated protein folding(GO:0061077)
1.6	13.1	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)

Showing 1 to 10 of 69 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	236.8	GO:0005615	extracellular space(GO:0005615)
3.1	31.1	GO:0042587	glycogen granule(GO:0042587)
0.7	30.2	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.3	25.7	GO:0030315	T-tubule(GO:0030315)
1.3	18.1	GO:0097208	alveolar lamellar body(GO:0097208)
1.5	14.9	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.1	12.0	GO:0042383	sarcolemma(GO:0042383)
2.1	10.6	GO:0044316	cone cell pedicle(GO:0044316)
0.2	9.4	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	9.0	GO:0009897	external side of plasma membrane(GO:0009897)

Showing 1 to 10 of 38 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	180.6	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.4	31.1	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.5	30.2	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.3	29.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.4	25.7	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	22.9	GO:0004984	olfactory receptor activity(GO:0004984)
0.6	22.6	GO:0030552	cAMP binding(GO:0030552)
0.1	18.5	GO:0004857	enzyme inhibitor activity(GO:0004857)
5.8	17.3	GO:0102007	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.7	14.9	GO:0048156	tau protein binding(GO:0048156)

Showing 1 to 10 of 60 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	100.8	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	18.9	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3	14.9	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.3	13.4	NABA COLLAGENS	Genes encoding collagen proteins
0.3	13.1	PID ILK PATHWAY	Integrin-linked kinase signaling
0.3	10.0	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.2	7.6	PID IL23 PATHWAY	IL23-mediated signaling events
0.2	5.5	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.2	5.0	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.2	4.7	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods

Showing 1 to 10 of 22 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
4.9	44.5	REACTOME DEFENSINS	Genes involved in Defensins
1.4	38.6	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.3	18.3	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.6	10.6	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.2	8.6	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2	7.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.3	6.7	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.5	6.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.3	6.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.1	5.3	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation

Showing 1 to 10 of 22 entries

Results for Ptf1a

Z-value: 0.89

Motif logo

Transcription factors associated with Ptf1a

Activity-expression correlation:

Activity profile of Ptf1a motif

Sorted Z-values of Ptf1a motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Ptf1a

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: