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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Prrx1_Isx_Prrxl1

Z-value: 0.81

Motif logo

Transcription factors associated with Prrx1_Isx_Prrxl1

Gene Symbol Gene ID Gene Info
ENSRNOG00000003720 paired related homeobox 1
ENSRNOG00000039808 intestine-specific homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Drgxrn6_v1_chr16_+_8823872_88238720.331.9e-09Click!
Prrx1rn6_v1_chr13_-_81214494_812145460.312.4e-08Click!
Isxrn6_v1_chr19_+_14198899_141988990.036.3e-01Click!

Activity profile of Prrx1_Isx_Prrxl1 motif

Sorted Z-values of Prrx1_Isx_Prrxl1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_198303168 21.79 ENSRNOT00000056262
myotubularin related protein 11
chr5_+_118574801 20.31 ENSRNOT00000035949
ubiquitin-conjugating enzyme E2U (putative)
chr18_-_24057917 20.30 ENSRNOT00000023874
Ras-like without CAAX 2
chr4_-_55011415 19.23 ENSRNOT00000056996
glutamate metabotropic receptor 8
chr4_-_61720956 18.38 ENSRNOT00000012879
aldo-keto reductase family 1 member B
chr20_+_31339787 17.96 ENSRNOT00000082463
apoptosis inducing factor, mitochondria associated 2
chr7_+_59200918 17.63 ENSRNOT00000085073
protein tyrosine phosphatase, receptor type, R
chr8_-_6305033 16.74 ENSRNOT00000029887
centrosomal protein 126
chr4_+_70252366 16.33 ENSRNOT00000073039
cell adhesion molecule L1-like
chr17_+_63635086 16.25 ENSRNOT00000020634
disco-interacting protein 2 homolog C
chr8_+_82038967 16.23 ENSRNOT00000079535
myosin VA
chr17_+_81922329 15.38 ENSRNOT00000031542
calcium voltage-gated channel auxiliary subunit beta 2
chr14_+_69800156 14.93 ENSRNOT00000072746
ligand dependent nuclear receptor corepressor-like
chr6_-_14523961 14.87 ENSRNOT00000071402
neurexin 1
chr6_-_2311781 14.55 ENSRNOT00000084171
cytochrome P450, family 1, subfamily b, polypeptide 1
chr7_-_52404774 13.69 ENSRNOT00000082100
neuron navigator 3
chr7_-_29171783 13.54 ENSRNOT00000079235
myosin binding protein C, slow type
chr11_+_20474483 13.38 ENSRNOT00000082417
ENSRNOT00000002895
neural cell adhesion molecule 2
chr7_-_107768072 13.24 ENSRNOT00000093189
N-myc downstream regulated 1
chr18_+_30398113 13.05 ENSRNOT00000027206
protocadherin beta 5
chr2_+_266315036 12.75 ENSRNOT00000055245
wntless Wnt ligand secretion mediator
chr10_+_56381813 12.71 ENSRNOT00000019687
zinc finger and BTB domain containing 4
chr3_-_21904133 12.70 ENSRNOT00000090576
ENSRNOT00000087611
ENSRNOT00000066377
spermatid perinuclear RNA binding protein
chr2_-_156807305 12.61 ENSRNOT00000080578
uncharacterized protein LOC302022
chr8_+_126975833 12.31 ENSRNOT00000088348

chr8_-_102149912 12.30 ENSRNOT00000011263
similar to Ab2-095
chr2_-_40386669 12.03 ENSRNOT00000014074
ELOVL fatty acid elongase 7
chr3_-_134696654 11.98 ENSRNOT00000006454
fibronectin leucine rich transmembrane protein 3
chr9_+_73378057 11.75 ENSRNOT00000043627
ENSRNOT00000045766
ENSRNOT00000092445
ENSRNOT00000037974
microtubule-associated protein 2
chr3_+_5709236 11.72 ENSRNOT00000061201
ENSRNOT00000070887
dopamine beta-hydroxylase
chr10_-_15928169 11.56 ENSRNOT00000028069
neuron specific gene family member 2
chr5_+_103251986 11.55 ENSRNOT00000008757
centlein
chr3_+_173799833 11.36 ENSRNOT00000081235
phosphatase and actin regulator 3
chr6_+_8284878 11.26 ENSRNOT00000009581
solute carrier family 3 member 1
chr10_+_77537340 11.05 ENSRNOT00000003297
transmembrane protein 100
chr12_-_46493203 10.89 ENSRNOT00000057036
citron rho-interacting serine/threonine kinase
chrX_+_14019961 10.85 ENSRNOT00000004785
synaptotagmin-like 5
chr2_-_88763733 10.85 ENSRNOT00000059424
similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chrX_+_84064427 10.82 ENSRNOT00000046364
zinc finger protein 711
chr3_-_26056818 10.78 ENSRNOT00000044209
LDL receptor related protein 1B
chr14_-_66978499 10.73 ENSRNOT00000081601
slit guidance ligand 2
chr3_+_56056925 10.34 ENSRNOT00000088351
ENSRNOT00000010508
kelch-like family member 23
chr20_+_19325121 10.29 ENSRNOT00000058151
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr4_+_2055615 10.25 ENSRNOT00000007646
ring finger protein 32
chr1_+_234363994 10.22 ENSRNOT00000018137
RAR-related orphan receptor B
chr6_-_127319362 10.10 ENSRNOT00000012256
DEAD-box helicase 24
chr2_-_117454769 10.10 ENSRNOT00000068381
MDS1 and EVI1 complex locus
chr2_-_158156444 10.01 ENSRNOT00000088559
ventricular zone expressed PH domain-containing 1
chrX_+_9956370 10.00 ENSRNOT00000082316
peripheral plasma membrane protein CASK-like
chr13_-_76049363 9.88 ENSRNOT00000075865
ENSRNOT00000007455
BMP/retinoic acid inducible neural specific 2
chr13_+_78979321 9.73 ENSRNOT00000003857
ankyrin repeat domain 45
chr17_-_84247038 9.51 ENSRNOT00000068553
nebulette
chr5_-_57896475 9.44 ENSRNOT00000017903
similar to testes development-related NYD-SP22 isoform 1
chrX_-_40086870 9.39 ENSRNOT00000010027
small muscle protein, X-linked
chr1_+_60884761 9.36 ENSRNOT00000088689
vomeronasal 1 receptor, F4-like
chr4_-_17440506 9.12 ENSRNOT00000080931
semaphorin 3E
chr8_+_117062884 9.03 ENSRNOT00000082452
ENSRNOT00000071540
nicolin 1
chrM_+_9870 9.01 ENSRNOT00000044582
mitochondrially encoded NADH 4L dehydrogenase
chr3_-_64364101 8.93 ENSRNOT00000089065
zinc finger protein 385B
chr2_-_149444548 8.68 ENSRNOT00000018600
purinergic receptor P2Y12
chr15_+_62406873 8.62 ENSRNOT00000047572
olfactomedin 4
chr15_+_43298794 8.44 ENSRNOT00000012736
adrenoceptor alpha 1A
chr6_-_114476723 8.43 ENSRNOT00000005162
deiodinase, iodothyronine, type II
chr2_-_231648122 8.32 ENSRNOT00000014962
ankyrin 2
chr10_+_46722109 8.28 ENSRNOT00000032685
dynein regulatory complex subunit 3
chr7_-_75288365 8.19 ENSRNOT00000036904
ankyrin repeat domain 46
chr2_-_38110567 8.14 ENSRNOT00000072212
importin 11
chrM_+_10160 8.13 ENSRNOT00000042928
mitochondrially encoded NADH dehydrogenase 4
chr1_-_53802658 7.84 ENSRNOT00000032667
afadin, adherens junction formation factor
chr10_-_66848388 7.80 ENSRNOT00000018891
oligodendrocyte-myelin glycoprotein
chr19_-_24614019 7.77 ENSRNOT00000005124
short coiled-coil protein
chr1_-_67134827 7.59 ENSRNOT00000045214
vomeronasal 1 receptor 45
chr8_-_132753145 7.54 ENSRNOT00000007467
ENSRNOT00000008172
similar to Solute carrier family 6 (neurotransmitter transporter), member 20
chr9_+_84203072 7.38 ENSRNOT00000018882
sphingosine-1-phosphate phosphatase 2
chrX_-_77559348 7.36 ENSRNOT00000047823
fibronectin type III domain containing 3C1
chr14_-_3300200 7.21 ENSRNOT00000037931
BTB (POZ) domain containing 8
chr4_+_88328061 7.09 ENSRNOT00000084775
vomeronasal 1 receptor 87
chr1_+_53874860 7.04 ENSRNOT00000090486
t-complex-associated testis expressed 2
chr8_+_64489942 7.04 ENSRNOT00000083666
pyruvate kinase, muscle
chr10_+_97771264 6.99 ENSRNOT00000005257
arylsulfatase G
chr10_-_16731898 6.94 ENSRNOT00000028186
CREB3 regulatory factor
chr12_-_54885 6.70 ENSRNOT00000090447

chrX_-_142164220 6.68 ENSRNOT00000064780
fibroblast growth factor 13
chr17_-_14627937 6.59 ENSRNOT00000020532
osteoglycin
chr16_-_39476384 6.57 ENSRNOT00000092968
glycoprotein m6a
chr4_+_88184956 6.54 ENSRNOT00000077129
vomeronasal 1 receptor 83
chr18_+_30474947 6.48 ENSRNOT00000027188
protocadherin beta 9
chr4_+_88271061 6.47 ENSRNOT00000087374
vomeronasal 1 receptor 86
chr4_-_15859132 6.43 ENSRNOT00000082161
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr13_+_94888078 6.31 ENSRNOT00000077995
ENSRNOT00000005647
ENSRNOT00000077345
serologically defined colon cancer antigen 8
chr18_-_32207749 6.26 ENSRNOT00000090882
ENSRNOT00000018843
Rho GTPase activating protein 26
chr18_+_31444472 6.21 ENSRNOT00000075159
ring finger protein 14
chr6_+_29977797 6.13 ENSRNOT00000071784
FK506 binding protein 1B
chr10_-_91661558 6.13 ENSRNOT00000043156

chr3_+_155160481 6.03 ENSRNOT00000021133
protein phosphatase 1, regulatory subunit 16B
chr8_-_47094352 6.02 ENSRNOT00000048347
glutamate ionotropic receptor kainate type subunit 4
chr18_+_30487264 6.00 ENSRNOT00000040125
protocadherin beta 10
chr1_+_188420461 5.96 ENSRNOT00000037870
centriolar coiled-coil protein 110
chr17_+_16340226 5.93 ENSRNOT00000089140
protein tyrosine phosphatase domain containing 1
chrX_-_63803915 5.86 ENSRNOT00000076938
MAGE family member D1
chr20_+_20378861 5.83 ENSRNOT00000091044
ankyrin 3
chr2_+_242634399 5.77 ENSRNOT00000035700
endomucin
chr7_-_76294663 5.77 ENSRNOT00000064513
neurocalcin delta
chr7_-_143353925 5.74 ENSRNOT00000068533
keratin 71
chrX_+_118197217 5.70 ENSRNOT00000090922
5-hydroxytryptamine receptor 2C
chr3_+_8547349 5.58 ENSRNOT00000079108
ENSRNOT00000091697
spectrin, alpha, non-erythrocytic 1
chr9_+_60039297 5.58 ENSRNOT00000016262
solute carrier family 39 member 10
chr9_+_111597037 5.50 ENSRNOT00000021758
FER tyrosine kinase
chrM_+_9451 5.47 ENSRNOT00000041241
mitochondrially encoded NADH dehydrogenase 3
chr3_-_138683318 5.39 ENSRNOT00000029701
double zinc ribbon and ankyrin repeat domains 1
chr14_+_39663421 5.20 ENSRNOT00000003197
gamma-aminobutyric acid type A receptor alpha2 subunit
chr1_+_66959610 5.19 ENSRNOT00000072122
ENSRNOT00000045994
vomeronasal 1 receptor 48
chr3_+_81134505 5.18 ENSRNOT00000067664
PHD finger protein 21A
chr16_+_78539489 5.17 ENSRNOT00000057897
CUB and Sushi multiple domains 1
chr18_+_63203063 5.16 ENSRNOT00000024144
PRELI domain containing 3A
chr10_+_92289107 5.12 ENSRNOT00000050070
microtubule-associated protein tau
chr8_+_26432514 5.12 ENSRNOT00000081574
septin 7
chr15_+_56666012 5.12 ENSRNOT00000013408
5-hydroxytryptamine receptor 2A
chr1_+_61786900 4.98 ENSRNOT00000090287

chr8_-_83280888 4.97 ENSRNOT00000052341
GDNF family receptor alpha like
chrX_+_92131209 4.90 ENSRNOT00000004462
poly A binding protein, cytoplasmic 5
chr5_-_147412705 4.89 ENSRNOT00000010688
similar to mKIAA1522 protein
chr2_-_57935334 4.89 ENSRNOT00000022319
ENSRNOT00000085599
ENSRNOT00000077790
ENSRNOT00000035821
solute carrier family 1 member 3
chr7_-_70476340 4.86 ENSRNOT00000006800
Rho guanine nucleotide exchange factor 25
chrX_-_121731543 4.80 ENSRNOT00000018788
kelch-like family member 13
chr5_+_6373583 4.79 ENSRNOT00000084749

chr9_+_73418607 4.77 ENSRNOT00000092547
microtubule-associated protein 2
chr2_+_22000106 4.75 ENSRNOT00000061812
ankyrin repeat domain 34B
chr10_-_86645529 4.74 ENSRNOT00000011947
mediator complex subunit 24
chr3_-_25212049 4.74 ENSRNOT00000040023
LDL receptor related protein 1B
chr7_+_380741 4.74 ENSRNOT00000091013
nidogen-2-like
chr13_-_80775230 4.73 ENSRNOT00000091389
ENSRNOT00000004762
flavin containing monooxygenase 2
chr3_-_124724252 4.72 ENSRNOT00000028885
solute carrier family 23 member 2
chr2_-_257546799 4.69 ENSRNOT00000089370
ENSRNOT00000090367
mitoguardin 1
chr12_-_2174131 4.67 ENSRNOT00000001313
Purkinje cell protein 2
chr9_+_62291809 4.55 ENSRNOT00000090621
phospholipase C-like 1
chr4_+_155321553 4.51 ENSRNOT00000089614
microfibrillar associated protein 5
chr12_+_39423596 4.49 ENSRNOT00000066952
intraflagellar transport 81
chr7_+_23403891 4.46 ENSRNOT00000037918
synapsin III
chrX_+_144994139 4.45 ENSRNOT00000071783
pre-mRNA-splicing factor CWC22 homolog
chr11_-_72814850 4.44 ENSRNOT00000091575
UBX domain-containing protein 7-like
chrX_-_83151511 4.44 ENSRNOT00000057378
highly divergent homeobox
chr7_+_27174882 4.43 ENSRNOT00000051181
glycosyltransferase 8 domain containing 2
chr10_-_36323055 4.42 ENSRNOT00000081026
zinc finger protein 354C
chr4_+_88119838 4.39 ENSRNOT00000073173
vomeronasal 1 receptor 82
chrM_-_14061 4.38 ENSRNOT00000051268
mitochondrially encoded NADH dehydrogenase 6
chr11_+_20471764 4.38 ENSRNOT00000078127
neural cell adhesion molecule 2
chr6_+_48708368 4.36 ENSRNOT00000005905
myelin transcription factor 1-like
chr8_-_84835060 4.34 ENSRNOT00000007867
leucine rich repeat containing 1
chr1_-_67065797 4.28 ENSRNOT00000048152
vomeronasal 1 receptor 46
chr17_-_61332391 4.23 ENSRNOT00000034599
SNRPN upstream reading frame protein-like
chr17_-_87826421 4.23 ENSRNOT00000068156
Rho GTPase activating protein 21
chr1_-_84950210 4.20 ENSRNOT00000083050

chr3_+_56862691 4.19 ENSRNOT00000087712
glutamate decarboxylase 1
chr2_+_217963456 4.19 ENSRNOT00000024243
olfactomedin 3
chr8_+_64531594 4.14 ENSRNOT00000036798
GRAM domain containing 2
chr7_+_117456039 4.06 ENSRNOT00000051754
maestro heat-like repeat family member 1
chr18_+_30496318 4.03 ENSRNOT00000027179
protocadherin beta 11
chr5_-_115167986 4.02 ENSRNOT00000079786
cytochrome P450 2J3-like
chrX_-_123092217 4.01 ENSRNOT00000039710
predicted gene 14569
chr3_-_76696107 4.00 ENSRNOT00000044692
olfactory receptor 629
chr3_-_15278645 3.99 ENSRNOT00000032204
tubulin tyrosine ligase like11
chrM_+_14136 3.98 ENSRNOT00000042098
mitochondrially encoded cytochrome b
chr3_+_48082935 3.92 ENSRNOT00000087711
ENSRNOT00000067545
solute carrier family 4 member 10
chr9_-_61810417 3.90 ENSRNOT00000020910
raftlin family member 2
chr8_-_18762922 3.89 ENSRNOT00000008423
olfactory receptor 1122
chr2_+_143656793 3.87 ENSRNOT00000084527
ENSRNOT00000017453
periostin
chr2_+_58448917 3.87 ENSRNOT00000082562
RAN binding protein 3-like
chr10_+_17327275 3.86 ENSRNOT00000005486
ubiquitin domain containing 2
chr7_-_29152442 3.85 ENSRNOT00000079774
myosin binding protein C, slow type
chr5_+_154868534 3.84 ENSRNOT00000091442
leucine zipper protein 1
chr18_+_32336102 3.77 ENSRNOT00000018577
fibroblast growth factor 1
chr8_-_39551700 3.77 ENSRNOT00000091894
ENSRNOT00000076025
PBX/knotted 1 homeobox 2
chr6_+_64649194 3.75 ENSRNOT00000039776

chr2_+_200793571 3.74 ENSRNOT00000091444
hydroxyacid oxidase 2
chrX_-_37003642 3.72 ENSRNOT00000040770
ENSRNOT00000058834
ENSRNOT00000058833
adhesion G protein-coupled receptor G2
chr15_+_4209703 3.72 ENSRNOT00000082236
protein phosphatase 3 catalytic subunit beta
chr13_-_86671515 3.72 ENSRNOT00000082869

chr9_+_10941613 3.71 ENSRNOT00000070794
semaphorin 6B
chr20_+_37876650 3.67 ENSRNOT00000001054
gap junction protein, alpha 1
chr6_+_48452369 3.66 ENSRNOT00000044310
myelin transcription factor 1-like
chr3_+_76468294 3.63 ENSRNOT00000037779
olfactory receptor 619
chr16_+_32457521 3.63 ENSRNOT00000083579
chloride voltage-gated channel 3
chr14_-_28967980 3.60 ENSRNOT00000048175
adhesion G protein-coupled receptor L3
chr2_-_158156150 3.58 ENSRNOT00000016621
ventricular zone expressed PH domain-containing 1
chr16_-_81693000 3.57 ENSRNOT00000092353
lysosomal-associated membrane protein 1
chrX_+_908044 3.56 ENSRNOT00000072087
zinc finger protein 300
chr20_-_10013190 3.54 ENSRNOT00000084726
ENSRNOT00000089112
radial spoke head 1 homolog
chr12_-_52658275 3.54 ENSRNOT00000041981
zinc finger protein 605
chr5_-_167696348 3.50 ENSRNOT00000024581
solute carrier family 45, member 1
chr18_+_30036887 3.48 ENSRNOT00000077824
protocadherin alpha 4
chr16_-_74496731 3.46 ENSRNOT00000015790
mitochondrial ribosomal protein S31
chr14_+_42015347 3.45 ENSRNOT00000044017
ATPase phospholipid transporting 8A1
chr1_-_22281788 3.45 ENSRNOT00000021318
syntaxin 7
chrM_+_7006 3.42 ENSRNOT00000043693
mitochondrially encoded cytochrome c oxidase II
chr3_+_80670140 3.42 ENSRNOT00000085614
autophagy and beclin 1 regulator 1
chr5_-_25721072 3.41 ENSRNOT00000021839
transmembrane protein 67
chr17_-_15566332 3.39 ENSRNOT00000093743
extracellular matrix protein 2
chr8_-_8524643 3.39 ENSRNOT00000009418
contactin 5
chr3_+_47677720 3.38 ENSRNOT00000065340
T-box, brain, 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Prrx1_Isx_Prrxl1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 18.4 GO:0006059 hexitol metabolic process(GO:0006059)
5.1 15.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
4.9 14.6 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
4.4 17.6 GO:0038128 ERBB2 signaling pathway(GO:0038128)
4.2 12.7 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
4.1 16.2 GO:0051643 endoplasmic reticulum localization(GO:0051643)
3.9 11.7 GO:0046333 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
3.8 19.1 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
3.6 10.8 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
3.6 10.7 GO:0021836 chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024)
3.2 9.5 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
2.9 20.3 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
2.9 8.7 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
2.8 8.4 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
2.4 12.0 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
2.3 6.9 GO:1902211 regulation of prolactin signaling pathway(GO:1902211)
2.1 8.3 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
2.0 6.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
2.0 6.0 GO:0032053 ciliary basal body organization(GO:0032053)
1.8 9.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
1.7 19.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
1.7 17.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
1.7 5.1 GO:0016476 regulation of embryonic cell shape(GO:0016476)
1.6 6.4 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
1.6 11.0 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
1.6 4.7 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
1.6 7.8 GO:0034334 adherens junction maintenance(GO:0034334)
1.5 5.8 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.4 8.4 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
1.4 5.5 GO:0038109 Kit signaling pathway(GO:0038109) diapedesis(GO:0050904)
1.3 12.0 GO:0003344 pericardium morphogenesis(GO:0003344)
1.3 3.9 GO:1904209 cellular response to vitamin K(GO:0071307) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
1.3 3.8 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
1.2 3.7 GO:0018924 mandelate metabolic process(GO:0018924)
1.2 3.7 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
1.2 3.7 GO:0010643 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
1.2 13.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
1.2 3.6 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
1.2 4.7 GO:0072592 oxygen metabolic process(GO:0072592)
1.2 8.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
1.2 11.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
1.2 3.5 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
1.1 10.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
1.1 3.3 GO:0045763 regulation of arginine metabolic process(GO:0000821) negative regulation of cellular amino acid metabolic process(GO:0045763)
1.1 1.1 GO:0035926 chemokine (C-C motif) ligand 2 secretion(GO:0035926)
1.1 3.2 GO:1903544 response to butyrate(GO:1903544)
1.0 12.5 GO:0035881 amacrine cell differentiation(GO:0035881)
1.0 6.7 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.9 3.8 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.9 2.8 GO:0046066 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216) dGDP metabolic process(GO:0046066)
0.9 2.8 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.9 3.6 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.9 6.1 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.9 2.6 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.9 3.4 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.9 8.6 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.8 4.2 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.8 2.5 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.8 2.4 GO:0018343 protein farnesylation(GO:0018343)
0.8 2.4 GO:0015692 nickel cation transport(GO:0015675) vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) nickel cation transmembrane transport(GO:0035444)
0.8 7.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.8 4.6 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.8 4.5 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.7 6.4 GO:0032596 protein transport into membrane raft(GO:0032596)
0.7 7.0 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.7 5.6 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.7 4.0 GO:0033590 response to cobalamin(GO:0033590)
0.7 3.3 GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
0.7 23.6 GO:0035640 exploration behavior(GO:0035640)
0.6 4.5 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.6 5.1 GO:1902474 negative regulation of mitochondrial fission(GO:0090258) regulation of cellular response to heat(GO:1900034) regulation of protein localization to synapse(GO:1902473) positive regulation of protein localization to synapse(GO:1902474)
0.6 12.7 GO:0007638 mechanosensory behavior(GO:0007638)
0.6 3.7 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.6 7.4 GO:0006670 sphingosine metabolic process(GO:0006670)
0.6 5.3 GO:0009642 response to light intensity(GO:0009642)
0.6 4.7 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.6 2.9 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.6 1.7 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.6 1.7 GO:0018094 protein polyglycylation(GO:0018094)
0.6 1.7 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.6 3.9 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.6 2.2 GO:1904959 regulation of cytochrome-c oxidase activity(GO:1904959)
0.6 2.2 GO:0061107 seminal vesicle development(GO:0061107)
0.6 17.8 GO:0007413 axonal fasciculation(GO:0007413)
0.5 2.1 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
0.5 5.9 GO:0007258 JUN phosphorylation(GO:0007258)
0.5 4.2 GO:0051683 establishment of Golgi localization(GO:0051683)
0.5 1.5 GO:0072720 response to dithiothreitol(GO:0072720)
0.5 2.5 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.5 10.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.5 2.4 GO:0060014 granulosa cell differentiation(GO:0060014)
0.5 3.4 GO:0001661 conditioned taste aversion(GO:0001661)
0.5 10.9 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.5 2.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.5 5.6 GO:0006108 malate metabolic process(GO:0006108)
0.5 1.8 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.5 1.4 GO:0035425 autocrine signaling(GO:0035425) paracrine signaling(GO:0038001)
0.4 16.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.4 2.7 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.4 20.1 GO:0016574 histone ubiquitination(GO:0016574)
0.4 2.6 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.4 2.1 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.4 3.8 GO:0001842 neural fold formation(GO:0001842)
0.4 2.1 GO:1904923 regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.4 0.8 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.4 1.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.4 2.4 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.4 4.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.4 3.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.4 3.4 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.4 1.1 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.4 1.8 GO:0051036 regulation of endosome size(GO:0051036)
0.3 2.8 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.3 5.2 GO:0001967 suckling behavior(GO:0001967)
0.3 1.7 GO:0035627 ceramide transport(GO:0035627)
0.3 6.9 GO:0001964 startle response(GO:0001964)
0.3 1.0 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.3 3.6 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.3 0.3 GO:0072011 glomerular endothelium development(GO:0072011)
0.3 1.0 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.3 16.7 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.3 12.3 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.3 7.8 GO:0048679 regulation of axon regeneration(GO:0048679)
0.3 2.4 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.3 3.2 GO:0021860 pyramidal neuron development(GO:0021860)
0.3 1.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.3 0.3 GO:0090648 response to environmental enrichment(GO:0090648)
0.3 39.0 GO:0007416 synapse assembly(GO:0007416)
0.3 10.8 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.3 9.1 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.3 12.3 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.3 4.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.3 1.6 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.3 4.7 GO:0008053 mitochondrial fusion(GO:0008053)
0.3 0.8 GO:0000962 mitochondrial mRNA catabolic process(GO:0000958) positive regulation of mitochondrial RNA catabolic process(GO:0000962)
0.2 2.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2 1.0 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.2 6.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 2.1 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.2 2.6 GO:0015825 L-serine transport(GO:0015825)
0.2 0.5 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.2 6.1 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.2 10.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.2 6.0 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.2 1.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 4.5 GO:0097435 fibril organization(GO:0097435)
0.2 3.4 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.2 1.7 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.2 0.4 GO:0009826 unidimensional cell growth(GO:0009826)
0.2 1.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 2.5 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.2 0.8 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.2 20.8 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.2 1.2 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.2 10.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 0.6 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.2 1.2 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.2 2.5 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.2 2.7 GO:0060736 prostate gland growth(GO:0060736)
0.2 6.0 GO:1901099 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.2 4.4 GO:0045109 intermediate filament organization(GO:0045109)
0.2 0.5 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of IRE1-mediated unfolded protein response(GO:1903896) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.2 5.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 2.0 GO:0051639 actin filament network formation(GO:0051639)
0.2 1.8 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.2 2.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.2 1.0 GO:0060723 regulation of spongiotrophoblast cell proliferation(GO:0060721) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.2 8.0 GO:0042220 response to cocaine(GO:0042220)
0.2 0.3 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.2 1.6 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.2 0.8 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 1.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 2.9 GO:0031103 axon regeneration(GO:0031103)
0.1 1.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.6 GO:0046519 sphingoid metabolic process(GO:0046519)
0.1 5.6 GO:0051693 actin filament capping(GO:0051693)
0.1 0.4 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1 0.5 GO:0070127 alanyl-tRNA aminoacylation(GO:0006419) tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 1.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 3.5 GO:0006829 zinc II ion transport(GO:0006829)
0.1 0.4 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.7 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 0.7 GO:0032439 endosome localization(GO:0032439)
0.1 2.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 0.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 1.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 1.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 1.0 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 3.9 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 2.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.1 1.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 1.6 GO:0007567 parturition(GO:0007567)
0.1 1.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 1.7 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.1 0.3 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655)
0.1 1.0 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1 5.9 GO:0031023 microtubule organizing center organization(GO:0031023)
0.1 0.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 2.6 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.1 5.3 GO:0035082 axoneme assembly(GO:0035082)
0.1 5.2 GO:0015914 phospholipid transport(GO:0015914)
0.1 1.1 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.6 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 1.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.7 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 1.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.4 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.6 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 4.8 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 1.4 GO:0006415 translational termination(GO:0006415)
0.1 1.7 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 0.2 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 3.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.3 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
0.1 5.7 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.7 GO:0045176 apical protein localization(GO:0045176)
0.1 1.8 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1 1.6 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 2.3 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1 0.6 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 8.0 GO:0006941 striated muscle contraction(GO:0006941)
0.1 1.0 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.1 1.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 5.2 GO:0006865 amino acid transport(GO:0006865)
0.1 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.1 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 1.6 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 1.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.3 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 10.6 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 2.1 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 1.9 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 3.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.2 GO:0042073 intraciliary transport(GO:0042073)
0.0 2.7 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.8 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 5.3 GO:0030198 extracellular matrix organization(GO:0030198)
0.0 5.9 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 2.2 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 1.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.6 GO:0016180 snRNA processing(GO:0016180)
0.0 0.5 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.5 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.2 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 1.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.7 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.1 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 1.3 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 1.0 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.6 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 1.0 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 4.2 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.0 0.4 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.8 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 0.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.7 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.2 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.8 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.3 GO:0032370 positive regulation of lipid transport(GO:0032370)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 16.2 GO:0042642 actomyosin, myosin complex part(GO:0042642)
5.1 20.3 GO:0033503 HULC complex(GO:0033503)
3.7 18.4 GO:0097454 Schwann cell microvillus(GO:0097454)
2.9 11.7 GO:0034774 secretory granule lumen(GO:0034774)
2.6 23.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
1.9 9.4 GO:0005927 muscle tendon junction(GO:0005927)
1.8 21.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
1.6 4.7 GO:0031230 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
1.4 17.4 GO:0005859 muscle myosin complex(GO:0005859)
1.3 5.1 GO:0045298 tubulin complex(GO:0045298)
1.1 3.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
1.0 5.1 GO:0005940 septin ring(GO:0005940)
1.0 6.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.9 3.6 GO:0061474 phagolysosome membrane(GO:0061474)
0.9 3.4 GO:0070820 tertiary granule(GO:0070820)
0.9 9.4 GO:0002177 manchette(GO:0002177)
0.8 2.5 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.8 2.4 GO:0070826 paraferritin complex(GO:0070826)
0.8 33.4 GO:0044295 axonal growth cone(GO:0044295)
0.8 12.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.7 12.3 GO:0042581 specific granule(GO:0042581)
0.6 5.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.6 3.7 GO:0005955 calcineurin complex(GO:0005955)
0.6 5.6 GO:0032437 cuticular plate(GO:0032437)
0.6 11.0 GO:0031430 M band(GO:0031430)
0.6 1.7 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.5 16.7 GO:0097546 ciliary base(GO:0097546)
0.5 25.4 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.5 14.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.4 2.1 GO:0000322 storage vacuole(GO:0000322)
0.4 2.5 GO:0000125 PCAF complex(GO:0000125)
0.4 4.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.4 2.4 GO:0036449 microtubule minus-end(GO:0036449)
0.4 13.6 GO:0060077 inhibitory synapse(GO:0060077)
0.4 1.4 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.3 5.1 GO:0070852 cell body fiber(GO:0070852)
0.3 1.0 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.3 1.0 GO:0044609 DBIRD complex(GO:0044609)
0.3 1.5 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.3 0.9 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.3 19.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 0.8 GO:0045025 mitochondrial degradosome(GO:0045025)
0.3 20.8 GO:0042734 presynaptic membrane(GO:0042734)
0.3 13.4 GO:0009925 basal plasma membrane(GO:0009925)
0.3 3.5 GO:0072687 meiotic spindle(GO:0072687)
0.2 2.5 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 7.5 GO:0034451 centriolar satellite(GO:0034451)
0.2 3.7 GO:0005916 fascia adherens(GO:0005916)
0.2 2.9 GO:0045275 respiratory chain complex III(GO:0045275)
0.2 12.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 3.4 GO:0036038 MKS complex(GO:0036038)
0.2 18.0 GO:0005811 lipid particle(GO:0005811)
0.2 4.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.2 1.3 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2 2.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.2 2.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2 15.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 11.8 GO:0030315 T-tubule(GO:0030315)
0.2 6.7 GO:0014704 intercalated disc(GO:0014704)
0.2 3.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 3.7 GO:0043034 costamere(GO:0043034)
0.2 19.2 GO:0005814 centriole(GO:0005814)
0.2 6.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 1.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 15.4 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.2 5.5 GO:0070469 respiratory chain(GO:0070469)
0.2 3.4 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.0 GO:0030896 checkpoint clamp complex(GO:0030896)
0.2 6.7 GO:0016235 aggresome(GO:0016235)
0.2 0.5 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.1 13.3 GO:0031985 Golgi cisterna(GO:0031985)
0.1 1.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 4.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 9.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.4 GO:0000814 ESCRT II complex(GO:0000814)
0.1 1.8 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 2.0 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 3.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 8.9 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 7.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.7 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 2.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.6 GO:0030061 mitochondrial crista(GO:0030061)
0.1 4.7 GO:0016592 mediator complex(GO:0016592)
0.1 1.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.7 GO:0031415 NatA complex(GO:0031415)
0.1 10.7 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.0 GO:0017119 Golgi transport complex(GO:0017119)
0.1 4.4 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 11.0 GO:0070382 exocytic vesicle(GO:0070382)
0.1 1.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 6.1 GO:0043204 perikaryon(GO:0043204)
0.1 0.7 GO:0045179 apical cortex(GO:0045179)
0.1 2.6 GO:0005771 multivesicular body(GO:0005771)
0.1 1.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 3.4 GO:0032587 ruffle membrane(GO:0032587)
0.1 18.9 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 0.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 23.3 GO:0005635 nuclear envelope(GO:0005635)
0.1 3.7 GO:0031526 brush border membrane(GO:0031526)
0.1 32.1 GO:0030425 dendrite(GO:0030425)
0.1 9.4 GO:0005938 cell cortex(GO:0005938)
0.1 0.5 GO:0030914 STAGA complex(GO:0030914)
0.1 6.3 GO:0043209 myelin sheath(GO:0043209)
0.1 16.4 GO:0016607 nuclear speck(GO:0016607)
0.1 11.4 GO:0030424 axon(GO:0030424)
0.1 6.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 3.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.2 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 4.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.3 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.8 GO:0031253 cell projection membrane(GO:0031253)
0.0 11.7 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 12.5 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 3.3 GO:0005759 mitochondrial matrix(GO:0005759)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 19.2 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
3.9 11.7 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
3.6 10.8 GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding(GO:0071886)
2.8 8.4 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
2.7 10.7 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
2.6 15.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
2.5 33.1 GO:0030215 semaphorin receptor binding(GO:0030215)
2.5 7.4 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
2.1 6.4 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
2.1 14.9 GO:0097109 neuroligin family protein binding(GO:0097109)
2.0 10.2 GO:0008502 melatonin receptor activity(GO:0008502)
1.8 12.7 GO:0031852 mu-type opioid receptor binding(GO:0031852)
1.8 7.0 GO:0004743 pyruvate kinase activity(GO:0004743)
1.7 5.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
1.6 4.7 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
1.5 18.4 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
1.3 17.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
1.3 5.3 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
1.3 5.1 GO:0099609 microtubule lateral binding(GO:0099609)
1.2 3.7 GO:0052854 very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
1.2 8.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
1.2 3.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
1.2 12.0 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
1.1 12.5 GO:0045499 chemorepellent activity(GO:0045499)
1.1 3.3 GO:0099567 N-terminal myristoylation domain binding(GO:0031997) calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099567)
1.1 28.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.1 4.2 GO:0008940 nitrate reductase activity(GO:0008940)
1.0 5.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
1.0 8.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
1.0 7.0 GO:0004065 arylsulfatase activity(GO:0004065)
1.0 7.8 GO:0030274 LIM domain binding(GO:0030274)
1.0 4.9 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.9 2.8 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.9 3.7 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.9 3.7 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.9 16.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.9 6.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.8 1.7 GO:0032551 UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.8 4.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.8 2.5 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.8 2.4 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) nickel cation transmembrane transporter activity(GO:0015099) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) chromium ion transmembrane transporter activity(GO:0070835)
0.7 3.7 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.7 16.5 GO:0002162 dystroglycan binding(GO:0002162)
0.7 3.4 GO:0070052 collagen V binding(GO:0070052)
0.7 17.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.7 17.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.6 12.9 GO:0031005 filamin binding(GO:0031005)
0.6 3.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.6 1.8 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.6 6.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.6 13.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.6 5.9 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.6 18.0 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.6 1.7 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.6 3.3 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.5 1.6 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.5 52.4 GO:0016503 pheromone receptor activity(GO:0016503)
0.5 2.4 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.5 5.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.4 18.3 GO:0070330 aromatase activity(GO:0070330)
0.4 3.1 GO:1903136 cuprous ion binding(GO:1903136)
0.4 1.7 GO:0017089 glycolipid transporter activity(GO:0017089)
0.4 20.5 GO:0030507 spectrin binding(GO:0030507)
0.4 1.2 GO:0017042 glycosylceramidase activity(GO:0017042)
0.4 6.4 GO:0044548 S100 protein binding(GO:0044548)
0.4 12.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.4 1.6 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.4 2.8 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.4 2.6 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.4 1.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.4 1.4 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.3 4.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.3 3.2 GO:0051378 serotonin binding(GO:0051378)
0.3 1.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.3 7.5 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.3 2.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3 2.7 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.3 1.3 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.3 1.0 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.2 5.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 1.6 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.2 3.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 2.6 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 7.2 GO:0050681 androgen receptor binding(GO:0050681)
0.2 2.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.2 9.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 0.6 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.2 0.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.0 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2 1.5 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.2 0.5 GO:0047522 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.2 0.9 GO:0015616 DNA translocase activity(GO:0015616)
0.2 1.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.2 0.8 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.2 1.0 GO:0009378 four-way junction helicase activity(GO:0009378)
0.2 4.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.2 9.3 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.2 10.9 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.2 3.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 2.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 2.6 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 11.3 GO:0030276 clathrin binding(GO:0030276)
0.1 17.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 10.3 GO:0097110 scaffold protein binding(GO:0097110)
0.1 0.4 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.5 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 3.8 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 5.6 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 13.0 GO:0030674 protein binding, bridging(GO:0030674)
0.1 10.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.8 GO:0005123 death receptor binding(GO:0005123)
0.1 2.7 GO:0008527 taste receptor activity(GO:0008527)
0.1 1.6 GO:0015643 toxic substance binding(GO:0015643)
0.1 3.3 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 4.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 22.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 2.0 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 7.7 GO:0002039 p53 binding(GO:0002039)
0.1 6.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 3.1 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.7 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.1 8.2 GO:0005262 calcium channel activity(GO:0005262)
0.1 2.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.3 GO:0035497 cAMP response element binding(GO:0035497)
0.1 2.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 5.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 1.4 GO:0001618 virus receptor activity(GO:0001618)
0.1 2.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 1.1 GO:0005521 lamin binding(GO:0005521)
0.1 0.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.0 GO:0048156 tau protein binding(GO:0048156)
0.1 3.0 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 1.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.9 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 2.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 7.0 GO:0008565 protein transporter activity(GO:0008565)
0.1 0.7 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 3.2 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 3.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 16.3 GO:0030695 GTPase regulator activity(GO:0030695)
0.1 0.6 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.5 GO:0042923 neuropeptide binding(GO:0042923)
0.1 3.9 GO:0046332 SMAD binding(GO:0046332)
0.1 2.0 GO:0005109 frizzled binding(GO:0005109)
0.1 13.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 0.5 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 3.9 GO:0043130 ubiquitin binding(GO:0043130)
0.1 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 10.5 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 1.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.9 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.4 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 1.3 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 2.8 GO:0051082 unfolded protein binding(GO:0051082)
0.0 10.3 GO:0045296 cadherin binding(GO:0045296)
0.0 1.1 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.4 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 2.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.8 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.6 GO:0044325 ion channel binding(GO:0044325)
0.0 1.0 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 3.0 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.0 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 20.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.5 5.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.3 11.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.3 10.4 PID RHOA PATHWAY RhoA signaling pathway
0.3 17.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.3 16.5 PID LKB1 PATHWAY LKB1 signaling events
0.2 9.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 7.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 15.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 15.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.2 3.7 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.2 2.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 5.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 4.8 PID AURORA B PATHWAY Aurora B signaling
0.1 2.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 3.8 PID FGF PATHWAY FGF signaling pathway
0.1 2.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 3.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 2.1 PID BARD1 PATHWAY BARD1 signaling events
0.1 2.6 NABA COLLAGENS Genes encoding collagen proteins
0.1 0.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.3 PID ATM PATHWAY ATM pathway
0.0 1.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 7.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 ST ADRENERGIC Adrenergic Pathway
0.0 1.0 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 1.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 22.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
1.0 20.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.9 16.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.9 15.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.9 11.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.9 19.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.8 11.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.7 18.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.7 7.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.7 12.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.6 16.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.5 9.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.5 10.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.4 17.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.4 5.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.4 3.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.4 4.5 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.4 12.0 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.4 10.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4 8.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.3 5.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.3 5.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.3 3.8 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.3 4.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.3 3.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.3 9.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 2.9 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.2 3.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 4.8 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 2.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 7.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 2.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 3.1 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.2 2.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 5.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 1.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 1.7 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2 1.3 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 3.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 9.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 3.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 6.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 3.0 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 9.7 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 5.1 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 5.5 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.1 5.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.8 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 1.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 4.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 4.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.8 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 13.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 3.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 5.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.7 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 2.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.6 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 4.6 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.3 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 2.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions