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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Pparg_Rxrg

Z-value: 3.01

Motif logo

Transcription factors associated with Pparg_Rxrg

Gene Symbol Gene ID Gene Info
ENSRNOG00000008839 peroxisome proliferator-activated receptor gamma
ENSRNOG00000004537 retinoid X receptor gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rxrgrn6_v1_chr13_+_85818427_858184730.326.5e-09Click!
Ppargrn6_v1_chr4_+_147275334_147275334-0.227.9e-05Click!

Activity profile of Pparg_Rxrg motif

Sorted Z-values of Pparg_Rxrg motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_123638702 245.22 ENSRNOT00000082473
ENSRNOT00000044470
ENSRNOT00000092017
cytochrome P450, family 2, subfamily d, polypeptide 1
chr7_+_11490852 183.16 ENSRNOT00000044484
cAMP responsive element binding protein 3-like 3
chr2_-_243407608 180.65 ENSRNOT00000014631
microsomal triglyceride transfer protein
chr4_+_99063181 172.98 ENSRNOT00000008840
fatty acid binding protein 1
chr2_+_20857202 164.85 ENSRNOT00000078919
acyl-CoA thioesterase 12
chr8_-_50531423 164.14 ENSRNOT00000090985
ENSRNOT00000074942
apolipoprotein C3
chr7_-_123621102 154.80 ENSRNOT00000046024
cytochrome P450, family 2, subfamily d, polypeptide 5
chr14_+_22142364 154.74 ENSRNOT00000002699
sulfotransferase family 1B member 1
chr9_+_16924520 152.52 ENSRNOT00000025094
solute carrier family 22 member 7
chr11_+_65022100 145.77 ENSRNOT00000003934
nuclear receptor subfamily 1, group I, member 2
chr10_+_56662242 144.53 ENSRNOT00000086919
asialoglycoprotein receptor 1
chr7_-_123655896 140.64 ENSRNOT00000012413
cytochrome P450, family 2, subfamily d, polypeptide 2
chr1_-_259287684 135.82 ENSRNOT00000054724
cytochrome P450, family 2, subfamily c, polypeptide 22
chr12_+_52452273 134.22 ENSRNOT00000056680
ENSRNOT00000088381
peroxisomal membrane protein 2
chr7_-_123630045 133.21 ENSRNOT00000050002
cytochrome P450, family 2, subfamily d, polypeptide 1
chr10_+_56662561 131.50 ENSRNOT00000025254
asialoglycoprotein receptor 1
chr7_-_30105132 128.02 ENSRNOT00000091227
nuclear receptor subfamily 1, group H, member 4
chr10_-_56624526 124.93 ENSRNOT00000024973
acyl-CoA dehydrogenase, very long chain
chr2_-_178389608 122.52 ENSRNOT00000013262
electron transfer flavoprotein dehydrogenase
chr1_-_258766881 122.17 ENSRNOT00000015801
cytochrome P450, family 2, subfamily c, polypeptide 12
chr16_-_81822716 117.70 ENSRNOT00000026677
coagulation factor X
chr1_+_100470722 112.39 ENSRNOT00000086917
aspartate dehydrogenase domain containing
chr1_-_89543967 111.82 ENSRNOT00000079631
hepsin
chr1_+_20856187 107.52 ENSRNOT00000071726
small leucine-rich protein 1
chr2_+_188449210 104.91 ENSRNOT00000027700
pyruvate kinase, liver and RBC
chr18_+_70733872 104.87 ENSRNOT00000067018
acetyl-CoA acyltransferase 2
chr16_-_81834945 103.86 ENSRNOT00000037806
coagulation factor VII
chr2_+_200452624 103.62 ENSRNOT00000026121
3-hydroxy-3-methylglutaryl-CoA synthase 2
chr3_+_171213936 100.45 ENSRNOT00000031586
phosphoenolpyruvate carboxykinase 1
chr1_+_88955440 95.98 ENSRNOT00000091101
proline dehydrogenase 2
chr1_+_219329574 95.14 ENSRNOT00000071109
calcium binding protein 2
chr1_+_88955135 94.24 ENSRNOT00000083550
proline dehydrogenase 2
chrX_-_13601069 94.11 ENSRNOT00000004686
ornithine carbamoyltransferase
chr2_+_60337667 92.84 ENSRNOT00000024035
alanine-glyoxylate aminotransferase 2
chr20_-_12820466 91.15 ENSRNOT00000001699
formimidoyltransferase cyclodeaminase
chrX_+_45420596 87.04 ENSRNOT00000051897
steroid sulfatase (microsomal), isozyme S
chr10_+_64952119 86.42 ENSRNOT00000012154
pipecolic acid and sarcosine oxidase
chr1_+_219833299 86.40 ENSRNOT00000087432
pyruvate carboxylase
chr4_+_153876149 86.11 ENSRNOT00000018083
solute carrier family 6 member 13
chr7_+_2689501 84.64 ENSRNOT00000041341
apolipoprotein F
chr1_+_83163079 84.35 ENSRNOT00000077725
ENSRNOT00000034845
cytochrome P450, family 2, subfamily b, polypeptide 3
chrX_-_23139694 83.79 ENSRNOT00000033656
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr13_-_102721218 83.61 ENSRNOT00000005459
mitochondrial amidoxime reducing component 1
chr1_-_98486976 83.49 ENSRNOT00000024083
electron transfer flavoprotein beta subunit
chr7_+_28412198 82.54 ENSRNOT00000081822
ENSRNOT00000038780
ENSRNOT00000005995
insulin-like growth factor 1
chr2_-_23256158 81.40 ENSRNOT00000015336
betaine-homocysteine S-methyltransferase
chr17_+_22620721 80.34 ENSRNOT00000019478
androgen-dependent TFPI-regulating protein
chr17_+_9736577 79.67 ENSRNOT00000066586
coagulation factor XII
chr7_-_3386522 79.05 ENSRNOT00000010760
methyltransferase like 7B
chr4_+_65110746 78.38 ENSRNOT00000017675
aldo-keto reductase family 1, member D1
chr1_+_282567674 76.90 ENSRNOT00000090543
carboxylesterase 2I
chr14_+_77079402 75.88 ENSRNOT00000042200
solute carrier family 2 member 9
chr13_+_56598957 75.23 ENSRNOT00000016944
ENSRNOT00000080335
ENSRNOT00000089913
coagulation factor XIII B chain
chr7_-_70661891 74.23 ENSRNOT00000010240
inhibin beta C subunit
chr13_+_89597138 73.54 ENSRNOT00000004662
apolipoprotein A2
chr17_+_9736786 73.34 ENSRNOT00000081920
coagulation factor XII
chr8_-_60086403 72.62 ENSRNOT00000020544
electron transfer flavoprotein alpha subunit
chr4_-_176679815 71.64 ENSRNOT00000090122
glycogen synthase 2
chr13_+_85580828 71.05 ENSRNOT00000005611
aldehyde dehydrogenase 9 family, member A1
chr10_-_38774449 70.94 ENSRNOT00000049820
liver-expressed antimicrobial peptide 2
chr18_-_24929091 70.63 ENSRNOT00000019596
protein C
chr3_+_8832740 69.85 ENSRNOT00000022552
phytanoyl-CoA dioxygenase domain containing 1
chr3_-_14112851 69.72 ENSRNOT00000092736
complement C5
chr11_-_81660395 69.62 ENSRNOT00000048739
fetuin B
chr8_-_130550388 67.98 ENSRNOT00000026355
cytochrome P450, family 8, subfamily b, polypeptide 1
chr10_-_103848035 67.65 ENSRNOT00000029001
fatty acid desaturase 6
chr12_-_48238887 66.34 ENSRNOT00000078868
acetyl-CoA carboxylase beta
chr20_+_28989491 63.82 ENSRNOT00000074524
phospholipase A2, group XIIB
chr11_-_81639872 62.63 ENSRNOT00000047595
ENSRNOT00000090031
ENSRNOT00000081864
histidine-rich glycoprotein
chr5_+_165415136 62.24 ENSRNOT00000016317
ENSRNOT00000079407
mannan-binding lectin serine peptidase 2
chr8_-_119265157 61.69 ENSRNOT00000056100
receptor (chemosensory) transporter protein 3
chr5_+_120250616 61.52 ENSRNOT00000070967
adenylate kinase 4
chr1_-_198486157 61.36 ENSRNOT00000022758
zymogen granule protein 16
chr20_-_4561062 60.15 ENSRNOT00000065044
ENSRNOT00000092698
ENSRNOT00000060607
complement factor B
complement C2
chr8_-_111777602 59.93 ENSRNOT00000052317
ENSRNOT00000083855
similar to RIKEN cDNA 1300017J02
chr2_+_114413410 58.62 ENSRNOT00000015866
solute carrier family 2 member 2
chr1_+_213511874 58.60 ENSRNOT00000078080
ENSRNOT00000016883
cytochrome P450, family 2, subfamily e, polypeptide 1
chr2_-_53313884 58.55 ENSRNOT00000046951
growth hormone receptor
chr1_-_224533219 57.42 ENSRNOT00000051289
integral membrane transport protein UST5r
chr1_+_266482858 56.76 ENSRNOT00000027223
arsenite methyltransferase
chr2_-_260148589 56.18 ENSRNOT00000013238
acyl-CoA dehydrogenase, C-4 to C-12 straight chain
chr9_-_61690956 55.93 ENSRNOT00000066589
heat shock protein family D member 1
chr18_-_35071619 55.33 ENSRNOT00000075695
serine protease inhibitor Kazal-type 3-like
chr18_-_38185812 54.93 ENSRNOT00000017969
serine peptidase inhibitor, Kazal type 1-like
chr12_+_47254484 54.73 ENSRNOT00000001556
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chrX_+_21696772 54.31 ENSRNOT00000043559
hydroxysteroid (17-beta) dehydrogenase 10
chr7_+_3216497 54.16 ENSRNOT00000008909
matrix metallopeptidase 19
chr4_+_100218661 53.34 ENSRNOT00000079415
transmembrane protein 150A
chr1_-_146736261 53.17 ENSRNOT00000068167
fumarylacetoacetate hydrolase
chr1_-_89369960 52.93 ENSRNOT00000028545
hepcidin antimicrobial peptide
chr1_+_100471066 52.55 ENSRNOT00000067562
aspartate dehydrogenase domain containing
chr1_-_170431073 52.42 ENSRNOT00000024710
hemopexin
chr10_+_96639924 51.86 ENSRNOT00000004756
apolipoprotein H
chr18_-_36285444 51.59 ENSRNOT00000087852
PRELI domain containing 2
chr1_-_148119857 51.55 ENSRNOT00000040325
Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chr16_+_54153054 51.50 ENSRNOT00000090644
ENSRNOT00000014248
fibrinogen-like 1
chr10_+_109708755 51.44 ENSRNOT00000083601
glucagon receptor
chr9_-_4978892 50.61 ENSRNOT00000015189
sulfotransferase family 1C member 3
chr2_+_84645084 50.47 ENSRNOT00000015448
carboxymethylenebutenolidase homolog
chr3_-_51054378 48.90 ENSRNOT00000089243
growth factor receptor bound protein 14
chr12_-_48218955 48.09 ENSRNOT00000067975
ENSRNOT00000080557
ENSRNOT00000000821
acetyl-CoA carboxylase beta
chr3_+_114355798 47.88 ENSRNOT00000024658
ENSRNOT00000036435
solute carrier family 28 member 2
chr7_-_143793774 47.73 ENSRNOT00000079678
cysteine sulfinic acid decarboxylase
chr10_+_86399827 47.60 ENSRNOT00000009299
growth factor receptor bound protein 7
chr5_+_117698764 47.23 ENSRNOT00000011486
angiopoietin-like 3
chr7_-_143793970 46.29 ENSRNOT00000016205
cysteine sulfinic acid decarboxylase
chr1_+_193424812 46.18 ENSRNOT00000019939
aquaporin 8
chr2_+_243701962 46.14 ENSRNOT00000016891
alcohol dehydrogenase 4 (class II), pi polypeptide
chr16_+_18736154 46.10 ENSRNOT00000015723
mannose-binding lectin (protein A) 1
chr4_-_176381477 45.45 ENSRNOT00000048367
solute carrier organic anion transporter family, member 1a6
chr7_-_14435967 44.62 ENSRNOT00000074801
peptidoglycan recognition protein 2
chr4_-_176294997 44.59 ENSRNOT00000015112
ENSRNOT00000051461
ENSRNOT00000000026
ENSRNOT00000039877
ENSRNOT00000049303
kidney specific organic anion transporter
chr1_+_264741911 44.56 ENSRNOT00000019956
semaphorin 4G
chr14_-_84334066 44.50 ENSRNOT00000006160
mitochondrial fission process 1
chr13_-_85622314 44.36 ENSRNOT00000005719
microsomal glutathione S-transferase 3
chr3_+_154786215 43.72 ENSRNOT00000019787
lipopolysaccharide binding protein
chr13_+_82496022 43.65 ENSRNOT00000080759
coagulation factor V
chr2_+_219563783 43.63 ENSRNOT00000020267
dihydrolipoamide branched chain transacylase E2
chr10_-_109909646 43.62 ENSRNOT00000074362
ENSRNOT00000088907
dicarbonyl and L-xylulose reductase
chr1_+_189514553 43.58 ENSRNOT00000020039
acyl-CoA synthetase medium-chain family member 3
chr1_+_282694906 43.46 ENSRNOT00000074303
carboxylesterase 2C
chr6_+_107460668 41.74 ENSRNOT00000013515
acyl-CoA thioesterase 2
chr2_+_60949256 41.73 ENSRNOT00000025323
ENSRNOT00000040701
alpha-methylacyl-CoA racemase
chr2_+_221823687 41.72 ENSRNOT00000072735
dihydropyrimidine dehydrogenase
chr2_+_243502073 41.58 ENSRNOT00000015870
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr3_-_150108898 41.41 ENSRNOT00000022914
peroxisomal membrane protein 4
chr19_+_487723 40.87 ENSRNOT00000061734
carboxylesterase 2J
chr8_+_117455262 40.26 ENSRNOT00000027520
solute carrier family 25 member 20
chr17_+_69468427 40.18 ENSRNOT00000058413
similar to 20-alpha-hydroxysteroid dehydrogenase
chr20_+_13827132 39.92 ENSRNOT00000001664
D-dopachrome tautomerase
chr7_-_117187367 39.24 ENSRNOT00000014191
similar to dystonin isoform 1
chr20_+_14101659 39.16 ENSRNOT00000072696
guanylyl cyclase domain containing 1
chr9_+_95295701 38.25 ENSRNOT00000025045
UDP glucuronosyltransferase family 1 member A5
chr17_-_43543172 37.89 ENSRNOT00000080684
ENSRNOT00000029626
ENSRNOT00000082719
solute carrier family 17 member 3
chr7_+_71057911 37.66 ENSRNOT00000037218
retinol dehydrogenase 16 (all-trans)
chr10_+_103396155 37.57 ENSRNOT00000086924
G protein-coupled receptor, class C, group 5, member C
chr8_-_77398156 37.49 ENSRNOT00000091858
ENSRNOT00000085349
ENSRNOT00000082763
lipase C, hepatic type
chr3_-_5481144 37.09 ENSRNOT00000078429
surfeit 4
chr3_-_7141522 37.08 ENSRNOT00000014572
carboxyl ester lipase
chr10_-_70802782 36.60 ENSRNOT00000045867
chemokine (C-C motif) ligand 6
chr2_+_243656579 36.31 ENSRNOT00000036993
alcohol dehydrogenase 1 (class I)
chr10_+_90085559 36.21 ENSRNOT00000028332
N-acetylglutamate synthase
chr12_-_41627741 36.18 ENSRNOT00000001875
serine dehydratase
chr13_-_50549981 35.95 ENSRNOT00000003918
ENSRNOT00000080486
golgi transport 1A
chr1_+_221236773 35.89 ENSRNOT00000051979
solute carrier family 25, member 45
chr1_-_212579057 35.79 ENSRNOT00000025446
enoyl-CoA hydratase, mitochondrial-like
chr9_+_4807717 35.75 ENSRNOT00000092159
sulfotransferase 1C2-like
chr17_+_22619891 35.66 ENSRNOT00000060403
androgen-dependent TFPI-regulating protein
chr6_-_10899200 35.52 ENSRNOT00000089104
multiple coagulation factor deficiency 2
chr5_+_76812931 35.35 ENSRNOT00000059458
hydroxysteroid dehydrogenase like 2
chr2_+_235738416 35.14 ENSRNOT00000074209
ethanolamine-phosphate phospho-lyase
chr1_-_261853495 34.44 ENSRNOT00000021144
lysyl oxidase-like 4
chr8_+_103342929 34.43 ENSRNOT00000045455
Ab2-060
chr18_+_46148849 34.27 ENSRNOT00000026724
proline rich 16
chr1_-_258875572 34.17 ENSRNOT00000093005
cytochrome P450, family 2, subfamily c, polypeptide 13
chr14_+_17195014 33.83 ENSRNOT00000031667
C-X-C motif chemokine ligand 11
chr14_-_86164341 33.45 ENSRNOT00000086343
ENSRNOT00000080147
glucokinase
chr12_-_48627297 32.84 ENSRNOT00000000890
iron-sulfur cluster assembly enzyme
chr10_-_62254287 32.69 ENSRNOT00000004313
serpin family F member 1
chr9_+_4269160 32.44 ENSRNOT00000050420
sulfotransferase family 1C member 2
chr6_+_26051396 32.23 ENSRNOT00000006452
ribokinase
chr10_+_103395511 32.01 ENSRNOT00000004256
G protein-coupled receptor, class C, group 5, member C
chr9_+_81689802 31.93 ENSRNOT00000021432
villin 1
chr2_+_198965685 31.76 ENSRNOT00000000107
ENSRNOT00000091578
PDZ domain containing 1
chr12_+_30441055 31.75 ENSRNOT00000081099

chr3_-_93412058 31.72 ENSRNOT00000011230
catalase
chr1_-_226049929 31.00 ENSRNOT00000007320
bestrophin 1
chr2_-_148722263 30.78 ENSRNOT00000017868
stress-associated endoplasmic reticulum protein 1
chr20_-_45053640 30.68 ENSRNOT00000072256
similar to Na+ dependent glucose transporter 1
chr6_-_26385761 30.49 ENSRNOT00000073228
glucokinase regulator
chr7_+_143754892 30.46 ENSRNOT00000085896
sterol O-acyltransferase 2
chr1_-_222178725 30.37 ENSRNOT00000028697
estrogen related receptor, alpha
chr7_+_140781799 30.36 ENSRNOT00000087932
DnaJ heat shock protein family (Hsp40) member C22
chr10_+_71202456 30.18 ENSRNOT00000076893
HNF1 homeobox B
chr19_+_15139920 30.04 ENSRNOT00000074479
ENSRNOT00000020775
carboxylesterase 1F
chr20_-_3819200 29.90 ENSRNOT00000000542
ENSRNOT00000081486
hydroxysteroid (17-beta) dehydrogenase 8
chr1_-_198559568 29.86 ENSRNOT00000023080
quinolinate phosphoribosyltransferase
chr4_+_14109864 29.74 ENSRNOT00000076349
similar to fatty acid translocase/CD36
chr5_-_57372239 29.61 ENSRNOT00000012975
aquaporin 7
chr7_+_12314848 29.57 ENSRNOT00000028969
guanidinoacetate N-methyltransferase
chr9_+_11064605 29.42 ENSRNOT00000075121
signal transducing adaptor family member 2
chr4_-_145390447 28.92 ENSRNOT00000091965
ENSRNOT00000012136
cell death-inducing DFFA-like effector c
chr20_+_13827660 28.70 ENSRNOT00000093131
D-dopachrome tautomerase
chr7_-_12246729 28.61 ENSRNOT00000044030
receptor accessory protein 6
chr2_-_210809306 28.51 ENSRNOT00000047139
glutathione S-transferase mu 1
chr18_+_44810388 28.29 ENSRNOT00000021646
ENSRNOT00000089750
hydroxysteroid (17-beta) dehydrogenase 4
chr2_+_227455722 28.27 ENSRNOT00000064809
SEC24 homolog D, COPII coat complex component
chr1_+_213686046 27.95 ENSRNOT00000019808
NACHT, LRR and PYD domains-containing protein 6-like
chr13_-_112005052 27.56 ENSRNOT00000007879
G0/G1switch 2
chr1_-_53038229 27.38 ENSRNOT00000017282
mitochondrial pyruvate carrier 1
chr5_+_78222504 27.24 ENSRNOT00000019544
solute carrier family 31 member 1
chr3_-_46361092 27.04 ENSRNOT00000008987
CD302 molecule
chr13_-_80703615 26.94 ENSRNOT00000004599
flavin containing monooxygenase 4
chr8_+_91464229 26.78 ENSRNOT00000013249
branched chain keto acid dehydrogenase E1 subunit beta
chr1_+_35067490 25.97 ENSRNOT00000022790
ADAM metallopeptidase with thrombospondin type 1 motif, 16
chr2_+_188449718 25.83 ENSRNOT00000065791
pyruvate kinase, liver and RBC
chr14_-_79464770 25.72 ENSRNOT00000008932
GrpE-like 1, mitochondrial
chr11_+_87204175 25.62 ENSRNOT00000000306
solute carrier family 25 member 1
chr2_+_56426367 25.57 ENSRNOT00000016036
leukemia inhibitory factor receptor alpha
chr20_-_4530126 25.28 ENSRNOT00000000481
Ski2 like RNA helicase

Network of associatons between targets according to the STRING database.

First level regulatory network of Pparg_Rxrg

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
79.2 237.7 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
63.4 190.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
57.7 173.0 GO:0051977 lysophospholipid transport(GO:0051977)
55.0 164.9 GO:0006742 NADP catabolic process(GO:0006742)
51.0 153.0 GO:0002254 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353) activation of plasma proteins involved in acute inflammatory response(GO:0002541)
50.7 608.6 GO:0042738 exogenous drug catabolic process(GO:0042738)
46.8 514.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
42.7 128.0 GO:0034971 histone H3-R17 methylation(GO:0034971)
40.7 81.4 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
37.3 111.8 GO:0034769 basement membrane disassembly(GO:0034769)
34.8 104.5 GO:1904612 response to 2,3,7,8-tetrachlorodibenzodioxine(GO:1904612)
31.3 94.0 GO:0042412 taurine biosynthetic process(GO:0042412)
30.9 92.8 GO:0019265 glycine biosynthetic process, by transamination of glyoxylate(GO:0019265)
30.4 91.2 GO:0043606 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) formamide metabolic process(GO:0043606)
29.3 58.6 GO:0016098 monoterpenoid metabolic process(GO:0016098)
29.1 232.5 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
28.6 114.4 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
27.9 83.6 GO:0042126 nitrate metabolic process(GO:0042126)
26.1 130.3 GO:0006526 arginine biosynthetic process(GO:0006526)
25.9 103.6 GO:0034696 response to prostaglandin F(GO:0034696) ketone body biosynthetic process(GO:0046951)
25.1 100.5 GO:0006114 glycerol biosynthetic process(GO:0006114)
23.6 94.3 GO:0019477 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
22.1 154.7 GO:0009812 flavonoid metabolic process(GO:0009812)
21.6 86.4 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
21.0 104.9 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
20.9 62.6 GO:0097037 heme export(GO:0097037)
20.9 166.9 GO:0042866 pyruvate biosynthetic process(GO:0042866)
20.7 124.0 GO:0006069 ethanol oxidation(GO:0006069)
20.6 82.5 GO:0001834 trophectodermal cell proliferation(GO:0001834)
18.6 55.9 GO:0002424 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) protein import into mitochondrial intermembrane space(GO:0045041)
18.4 18.4 GO:0015744 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
18.1 72.5 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
18.0 72.0 GO:0015879 carnitine transport(GO:0015879)
16.6 49.8 GO:0061215 mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
16.2 372.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
14.6 43.7 GO:0015920 lipopolysaccharide transport(GO:0015920)
14.5 43.6 GO:0042732 D-xylose metabolic process(GO:0042732)
14.3 114.3 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
14.2 71.0 GO:0045329 carnitine biosynthetic process(GO:0045329)
13.9 41.7 GO:0006214 thymidine catabolic process(GO:0006214) pyrimidine deoxyribonucleoside catabolic process(GO:0046127)
13.6 204.0 GO:0035634 response to stilbenoid(GO:0035634)
13.5 148.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
13.2 52.9 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
13.1 52.4 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
12.5 75.1 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
12.5 37.5 GO:0010034 response to acetate(GO:0010034)
12.5 25.0 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
12.2 183.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
11.7 23.5 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
11.7 58.6 GO:0009758 carbohydrate utilization(GO:0009758) fructose transport(GO:0015755)
11.1 44.6 GO:0051958 methotrexate transport(GO:0051958)
10.7 32.2 GO:0019303 D-ribose catabolic process(GO:0019303)
10.2 40.9 GO:0032827 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
9.8 88.1 GO:0006600 creatine metabolic process(GO:0006600)
9.8 48.9 GO:0060283 negative regulation of oocyte development(GO:0060283)
9.6 115.5 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
9.6 76.4 GO:1902222 L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
9.5 28.5 GO:0018916 nitrobenzene metabolic process(GO:0018916)
9.1 27.4 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
8.9 44.5 GO:0015793 glycerol transport(GO:0015793)
8.8 309.4 GO:0019369 arachidonic acid metabolic process(GO:0019369)
8.4 33.5 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
8.3 24.9 GO:0090081 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
8.0 47.9 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
7.7 108.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
7.6 197.6 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
7.4 22.3 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
7.3 43.6 GO:0008050 female courtship behavior(GO:0008050)
7.2 35.9 GO:0000066 mitochondrial ornithine transport(GO:0000066)
7.2 43.1 GO:0038161 prolactin signaling pathway(GO:0038161)
7.1 113.8 GO:0046415 urate metabolic process(GO:0046415)
6.8 27.2 GO:1902861 copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
6.7 40.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
6.6 46.2 GO:0015722 canalicular bile acid transport(GO:0015722)
6.4 51.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
6.4 25.6 GO:0015746 citrate transport(GO:0015746)
6.4 25.6 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
6.4 31.9 GO:0060327 cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
6.1 18.4 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
6.0 29.9 GO:0046874 quinolinate metabolic process(GO:0046874)
6.0 41.7 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
5.9 11.9 GO:0000255 allantoin metabolic process(GO:0000255)
5.8 110.3 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
5.8 23.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
5.6 16.8 GO:1902988 regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949) neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996) positive regulation of neurofibrillary tangle assembly(GO:1902998)
5.5 38.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
5.4 26.9 GO:0042737 drug catabolic process(GO:0042737)
5.4 16.1 GO:0021524 visceral motor neuron differentiation(GO:0021524) pulmonary vein morphogenesis(GO:0060577)
5.4 37.7 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
5.3 21.3 GO:0051692 cellular oligosaccharide catabolic process(GO:0051692)
5.1 15.4 GO:1902218 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
5.1 15.3 GO:0003032 age-dependent response to oxidative stress(GO:0001306) detection of oxygen(GO:0003032) age-dependent general metabolic decline(GO:0007571)
5.1 15.3 GO:0032978 protein insertion into membrane from inner side(GO:0032978)
5.1 40.5 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
5.0 25.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
5.0 125.1 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
5.0 24.9 GO:0070541 response to platinum ion(GO:0070541)
4.8 23.9 GO:0060112 positive regulation of luteinizing hormone secretion(GO:0033686) generation of ovulation cycle rhythm(GO:0060112)
4.8 14.3 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
4.7 23.7 GO:0060744 positive regulation of exit from mitosis(GO:0031536) thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
4.7 18.9 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
4.7 14.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
4.7 14.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105) negative regulation of adipose tissue development(GO:1904178)
4.7 9.4 GO:0043465 regulation of fermentation(GO:0043465) regulation of NAD metabolic process(GO:1902688) regulation of glucose catabolic process to lactate via pyruvate(GO:1904023)
4.7 32.7 GO:0071279 cellular response to cobalt ion(GO:0071279)
4.5 13.5 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
4.4 13.3 GO:1901492 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) cardiac vascular smooth muscle cell development(GO:0060948) positive regulation of lymphangiogenesis(GO:1901492)
4.4 13.3 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
4.3 13.0 GO:2000422 regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
4.3 21.5 GO:0001582 detection of chemical stimulus involved in sensory perception of sweet taste(GO:0001582)
4.3 21.4 GO:1903278 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
4.3 38.3 GO:0052697 xenobiotic glucuronidation(GO:0052697)
4.2 12.7 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
4.2 12.7 GO:2000360 regulation of binding of sperm to zona pellucida(GO:2000359) negative regulation of binding of sperm to zona pellucida(GO:2000360)
4.2 20.8 GO:0050917 sensory perception of umami taste(GO:0050917)
4.0 43.7 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
4.0 31.7 GO:0010193 response to ozone(GO:0010193)
3.9 27.6 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
3.9 15.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
3.9 11.6 GO:0030505 inorganic diphosphate transport(GO:0030505)
3.8 7.6 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
3.8 18.8 GO:1904717 regulation of AMPA glutamate receptor clustering(GO:1904717)
3.7 47.6 GO:0034063 stress granule assembly(GO:0034063)
3.6 14.4 GO:0033030 negative regulation of hypersensitivity(GO:0002884) negative regulation of neutrophil apoptotic process(GO:0033030)
3.6 14.3 GO:0035995 detection of muscle stretch(GO:0035995)
3.6 14.3 GO:0016554 cytidine to uridine editing(GO:0016554)
3.5 56.8 GO:0009404 toxin metabolic process(GO:0009404)
3.5 38.8 GO:0001554 luteolysis(GO:0001554)
3.5 17.6 GO:0060018 astrocyte fate commitment(GO:0060018)
3.5 10.4 GO:0030091 protein repair(GO:0030091)
3.5 10.4 GO:1990792 response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
3.4 6.8 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
3.4 3.4 GO:1990108 protein linear deubiquitination(GO:1990108)
3.4 10.1 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
3.3 10.0 GO:0060849 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
3.3 6.6 GO:0030327 prenylated protein catabolic process(GO:0030327)
3.2 41.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
3.2 9.6 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
3.1 59.6 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
3.1 18.7 GO:0006145 purine nucleobase catabolic process(GO:0006145)
3.1 9.3 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
3.1 61.7 GO:0051205 protein insertion into membrane(GO:0051205)
3.1 9.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
3.0 15.2 GO:0015747 urate transport(GO:0015747)
2.9 8.8 GO:0051106 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106) protein localization to site of double-strand break(GO:1990166)
2.9 40.8 GO:0051923 sulfation(GO:0051923)
2.8 19.9 GO:0048539 bone marrow development(GO:0048539)
2.8 39.3 GO:0008210 estrogen metabolic process(GO:0008210)
2.8 25.3 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
2.8 14.0 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
2.8 8.3 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
2.8 85.8 GO:0033344 cholesterol efflux(GO:0033344)
2.8 38.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
2.7 49.3 GO:0042438 melanin biosynthetic process(GO:0042438)
2.7 54.7 GO:0033327 Leydig cell differentiation(GO:0033327)
2.7 24.3 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
2.7 8.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
2.7 2.7 GO:0006117 acetaldehyde metabolic process(GO:0006117)
2.6 13.2 GO:0060903 positive regulation of meiosis I(GO:0060903)
2.6 10.6 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
2.6 10.5 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
2.6 5.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
2.5 37.9 GO:0051450 myoblast proliferation(GO:0051450)
2.5 10.1 GO:0009597 detection of virus(GO:0009597)
2.5 10.0 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
2.5 17.6 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
2.5 12.5 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904) ether lipid metabolic process(GO:0046485)
2.4 26.8 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
2.4 9.7 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
2.4 28.9 GO:0034389 lipid particle organization(GO:0034389)
2.3 9.4 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
2.3 11.6 GO:0071233 cellular response to leucine(GO:0071233)
2.3 20.9 GO:0099562 maintenance of postsynaptic specialization structure(GO:0098880) maintenance of postsynaptic density structure(GO:0099562)
2.3 39.3 GO:0046033 AMP metabolic process(GO:0046033)
2.3 22.7 GO:0070327 thyroid hormone transport(GO:0070327)
2.3 11.3 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
2.3 11.3 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
2.2 8.9 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
2.2 15.5 GO:0048102 autophagic cell death(GO:0048102)
2.2 17.3 GO:1990034 calcium ion export from cell(GO:1990034)
2.2 32.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
2.1 38.5 GO:0006783 heme biosynthetic process(GO:0006783)
2.1 33.8 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
2.1 6.3 GO:0021699 cerebellar cortex maturation(GO:0021699)
2.0 8.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
2.0 12.0 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
2.0 16.0 GO:0019388 galactose catabolic process(GO:0019388)
2.0 5.9 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
2.0 11.9 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
1.9 34.3 GO:0045793 positive regulation of cell size(GO:0045793)
1.8 14.8 GO:0006751 glutathione catabolic process(GO:0006751)
1.8 78.2 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
1.8 5.4 GO:0046351 disaccharide biosynthetic process(GO:0046351)
1.8 9.0 GO:0002159 desmosome assembly(GO:0002159)
1.7 8.7 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
1.7 8.7 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
1.7 49.8 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
1.7 8.6 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
1.7 42.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
1.7 8.4 GO:0071918 urea transmembrane transport(GO:0071918)
1.7 11.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
1.7 9.9 GO:0097039 protein linear polyubiquitination(GO:0097039)
1.6 32.6 GO:0006098 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
1.6 6.5 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) endodermal digestive tract morphogenesis(GO:0061031)
1.6 6.5 GO:0006824 cobalt ion transport(GO:0006824)
1.6 52.7 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
1.6 7.8 GO:0006741 NADP biosynthetic process(GO:0006741)
1.6 18.8 GO:0009750 response to fructose(GO:0009750)
1.6 12.5 GO:0016191 synaptic vesicle uncoating(GO:0016191)
1.5 60.1 GO:0006635 fatty acid beta-oxidation(GO:0006635)
1.5 9.2 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) response to amino acid starvation(GO:1990928)
1.5 3.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
1.5 3.0 GO:2000739 regulation of mesenchymal stem cell differentiation(GO:2000739)
1.5 23.9 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
1.5 8.8 GO:0042148 meiotic DNA recombinase assembly(GO:0000707) strand invasion(GO:0042148)
1.4 21.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
1.4 8.6 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
1.4 7.2 GO:0045218 zonula adherens maintenance(GO:0045218)
1.4 2.9 GO:0071579 regulation of zinc ion transport(GO:0071579)
1.4 10.0 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
1.4 30.0 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
1.4 15.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
1.4 5.6 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
1.4 16.5 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
1.4 4.1 GO:0016559 peroxisome fission(GO:0016559)
1.3 4.0 GO:0042350 GDP-L-fucose biosynthetic process(GO:0042350)
1.3 1.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
1.3 12.1 GO:0006105 succinate metabolic process(GO:0006105)
1.3 8.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
1.3 9.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
1.3 10.6 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
1.3 51.6 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
1.3 36.9 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
1.3 14.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.3 3.9 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.3 2.6 GO:0061724 lipophagy(GO:0061724)
1.3 2.6 GO:0043932 ossification involved in bone remodeling(GO:0043932)
1.3 20.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
1.3 2.5 GO:1903181 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
1.3 25.3 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
1.3 5.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
1.3 3.8 GO:0034499 late endosome to Golgi transport(GO:0034499)
1.2 8.7 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
1.2 9.9 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
1.2 57.8 GO:0009268 response to pH(GO:0009268)
1.2 7.1 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
1.2 46.0 GO:0000266 mitochondrial fission(GO:0000266)
1.2 3.5 GO:0000958 mitochondrial mRNA catabolic process(GO:0000958) positive regulation of mitochondrial RNA catabolic process(GO:0000962) RNA 5'-end processing(GO:0000966) RNA import into mitochondrion(GO:0035927) rRNA import into mitochondrion(GO:0035928) polyadenylation-dependent RNA catabolic process(GO:0043633)
1.2 12.8 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
1.2 22.0 GO:0061436 establishment of skin barrier(GO:0061436)
1.1 2.3 GO:0009992 primary ovarian follicle growth(GO:0001545) cellular water homeostasis(GO:0009992)
1.1 11.4 GO:1902003 regulation of beta-amyloid formation(GO:1902003)
1.1 3.4 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
1.1 4.5 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
1.1 15.4 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
1.1 6.6 GO:0051503 ADP transport(GO:0015866) ATP transport(GO:0015867) adenine nucleotide transport(GO:0051503)
1.1 19.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
1.1 10.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
1.1 3.2 GO:0018343 protein farnesylation(GO:0018343)
1.1 4.2 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
1.1 7.4 GO:0060613 fat pad development(GO:0060613)
1.0 12.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
1.0 30.8 GO:0010259 multicellular organism aging(GO:0010259)
1.0 3.0 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
1.0 13.2 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
1.0 171.0 GO:0007596 blood coagulation(GO:0007596)
1.0 12.9 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
1.0 3.9 GO:0000459 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
1.0 25.3 GO:0000305 response to oxygen radical(GO:0000305)
1.0 7.7 GO:0034982 mitochondrial protein processing(GO:0034982)
0.9 10.4 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.9 36.8 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.9 7.5 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.9 8.5 GO:0019395 fatty acid oxidation(GO:0019395)
0.9 20.5 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.9 3.7 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.9 18.3 GO:0019915 lipid storage(GO:0019915)
0.9 10.0 GO:0006020 inositol metabolic process(GO:0006020)
0.9 2.7 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.9 3.5 GO:0001555 oocyte growth(GO:0001555)
0.9 8.7 GO:0001845 phagolysosome assembly(GO:0001845)
0.9 7.7 GO:0008206 bile acid metabolic process(GO:0008206)
0.9 27.3 GO:0050873 brown fat cell differentiation(GO:0050873)
0.8 20.9 GO:0097006 regulation of plasma lipoprotein particle levels(GO:0097006)
0.8 2.5 GO:0061144 alveolar secondary septum development(GO:0061144)
0.8 15.6 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.8 174.1 GO:0031668 cellular response to extracellular stimulus(GO:0031668)
0.8 15.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.8 51.8 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.8 20.8 GO:0006956 complement activation(GO:0006956)
0.8 4.8 GO:0060290 transdifferentiation(GO:0060290)
0.8 7.9 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.8 5.5 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.8 3.9 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.8 39.8 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.8 8.5 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.8 1.5 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.8 13.5 GO:0090161 Golgi ribbon formation(GO:0090161)
0.7 12.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.7 0.7 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.7 14.1 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.7 23.8 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.7 15.9 GO:0048240 sperm capacitation(GO:0048240)
0.7 7.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.7 14.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.7 11.7 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.7 31.4 GO:0016125 sterol metabolic process(GO:0016125)
0.7 7.5 GO:0006013 mannose metabolic process(GO:0006013)
0.7 5.4 GO:0051775 response to redox state(GO:0051775)
0.7 5.9 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.7 3.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.7 14.4 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.6 2.6 GO:0034227 tRNA thio-modification(GO:0034227)
0.6 11.0 GO:0043277 apoptotic cell clearance(GO:0043277)
0.6 6.3 GO:0016540 protein autoprocessing(GO:0016540)
0.6 26.5 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.6 15.8 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.6 22.0 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.6 8.8 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.6 4.2 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.6 48.5 GO:1903955 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.6 4.5 GO:0044804 nucleophagy(GO:0044804)
0.6 1.1 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.6 14.9 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.5 6.0 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.5 9.0 GO:0032098 regulation of appetite(GO:0032098)
0.5 1.6 GO:0046512 sphingosine biosynthetic process(GO:0046512)
0.5 9.3 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.5 6.7 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.5 1.4 GO:0061043 positive regulation of vascular wound healing(GO:0035470) regulation of vascular wound healing(GO:0061043)
0.5 3.7 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.5 4.5 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.4 18.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.4 21.6 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.4 3.4 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.4 6.2 GO:0060579 ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.4 2.9 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.4 11.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.4 3.6 GO:0007000 nucleolus organization(GO:0007000)
0.4 3.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.4 5.0 GO:0006491 N-glycan processing(GO:0006491)
0.4 5.0 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.4 1.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.3 2.7 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.3 1.0 GO:0018201 peptidyl-glycine modification(GO:0018201)
0.3 1.3 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.3 6.4 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857)
0.3 2.2 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.3 3.2 GO:0009062 fatty acid catabolic process(GO:0009062)
0.3 1.4 GO:0006102 isocitrate metabolic process(GO:0006102)
0.3 2.8 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.3 1.1 GO:1902416 regulation of mRNA binding(GO:1902415) positive regulation of mRNA binding(GO:1902416)
0.3 5.3 GO:0045332 phospholipid translocation(GO:0045332)
0.2 1.0 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2 2.0 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 4.6 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.2 5.8 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.2 10.0 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.2 1.3 GO:0000012 single strand break repair(GO:0000012)
0.2 1.5 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.2 2.8 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.2 2.0 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 7.4 GO:0032543 mitochondrial translation(GO:0032543)
0.2 4.1 GO:0009311 oligosaccharide metabolic process(GO:0009311)
0.2 4.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.2 92.3 GO:0055114 oxidation-reduction process(GO:0055114)
0.2 4.0 GO:0035902 response to immobilization stress(GO:0035902)
0.2 0.6 GO:2000814 positive regulation of barbed-end actin filament capping(GO:2000814)
0.2 0.5 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.1 0.4 GO:1903769 negative regulation of cell proliferation in bone marrow(GO:1903769)
0.1 0.3 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 15.7 GO:0006790 sulfur compound metabolic process(GO:0006790)
0.1 0.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 1.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 1.6 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
0.1 1.2 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 126.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 1.9 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 1.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.2 GO:0035973 aggrephagy(GO:0035973)
0.1 0.7 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 3.0 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.9 GO:0014850 response to muscle activity(GO:0014850)
0.1 1.6 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1 5.6 GO:0048706 embryonic skeletal system development(GO:0048706)
0.1 0.5 GO:2001204 regulation of osteoclast development(GO:2001204)
0.1 5.1 GO:0008033 tRNA processing(GO:0008033)
0.1 3.5 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 1.5 GO:0034605 cellular response to heat(GO:0034605)
0.0 1.5 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 1.9 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 0.5 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.6 GO:0048806 genitalia development(GO:0048806)
0.0 0.4 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.0 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
28.3 254.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
22.6 225.9 GO:0045179 apical cortex(GO:0045179)
18.2 91.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
16.5 82.5 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
15.7 62.6 GO:0061474 phagolysosome membrane(GO:0061474)
15.4 46.2 GO:0046691 intracellular canaliculus(GO:0046691)
11.7 58.6 GO:0070195 growth hormone receptor complex(GO:0070195)
11.2 55.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
10.0 70.2 GO:0060205 cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
10.0 69.7 GO:0005579 membrane attack complex(GO:0005579)
9.6 182.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
9.5 28.6 GO:0044317 rod spherule(GO:0044317)
8.7 174.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
8.4 25.3 GO:0055087 Ski complex(GO:0055087)
8.0 199.0 GO:0031528 microvillus membrane(GO:0031528)
6.1 24.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
6.0 18.0 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
5.4 167.7 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
5.4 26.8 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
4.9 256.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
4.7 32.7 GO:0043203 axon hillock(GO:0043203)
4.6 27.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
4.5 13.5 GO:0034666 integrin alpha2-beta1 complex(GO:0034666) integrin alpha3-beta1 complex(GO:0034667)
4.4 140.1 GO:0005719 nuclear euchromatin(GO:0005719)
4.3 21.5 GO:1903768 sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
4.0 12.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
3.9 1056.1 GO:0005759 mitochondrial matrix(GO:0005759)
3.8 11.3 GO:1990037 Lewy body core(GO:1990037)
3.6 14.3 GO:0035339 SPOTS complex(GO:0035339)
3.5 3.5 GO:0045025 mitochondrial degradosome(GO:0045025)
3.5 51.9 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
3.2 9.7 GO:0036117 hyaluranon cable(GO:0036117)
3.1 9.4 GO:0045203 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
2.8 38.7 GO:0030127 COPII vesicle coat(GO:0030127)
2.7 8.1 GO:0042627 chylomicron(GO:0042627)
2.6 7.9 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
2.5 7.6 GO:0035577 azurophil granule membrane(GO:0035577)
2.5 5.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
2.3 96.1 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
2.3 6.8 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
2.2 6.6 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
2.1 31.9 GO:0032433 filopodium tip(GO:0032433)
2.1 12.7 GO:0097422 tubular endosome(GO:0097422)
2.0 1643.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
2.0 626.3 GO:0005743 mitochondrial inner membrane(GO:0005743)
1.8 38.0 GO:0031091 platelet alpha granule(GO:0031091)
1.8 12.5 GO:0005833 hemoglobin complex(GO:0005833)
1.8 8.8 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
1.6 42.0 GO:0005902 microvillus(GO:0005902)
1.5 160.5 GO:0072562 blood microparticle(GO:0072562)
1.5 124.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
1.5 17.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
1.5 13.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
1.4 8.7 GO:0016461 unconventional myosin complex(GO:0016461)
1.4 73.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
1.4 4.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
1.3 3.9 GO:0060053 neurofilament cytoskeleton(GO:0060053)
1.3 20.9 GO:0005883 neurofilament(GO:0005883)
1.2 19.8 GO:0042589 zymogen granule membrane(GO:0042589)
1.2 11.1 GO:0061702 inflammasome complex(GO:0061702)
1.2 10.5 GO:0043202 lysosomal lumen(GO:0043202)
1.2 6.9 GO:0005879 axonemal microtubule(GO:0005879)
1.1 4.5 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
1.1 57.0 GO:0005811 lipid particle(GO:0005811)
1.1 63.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
1.0 7.2 GO:0036449 microtubule minus-end(GO:0036449)
1.0 50.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
1.0 140.2 GO:0005903 brush border(GO:0005903)
0.9 8.5 GO:0042588 zymogen granule(GO:0042588)
0.9 11.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.9 14.1 GO:0045180 basal cortex(GO:0045180)
0.9 11.1 GO:0005861 troponin complex(GO:0005861)
0.9 9.8 GO:0000791 euchromatin(GO:0000791)
0.9 4.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.8 110.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.8 4.8 GO:0031595 nuclear proteasome complex(GO:0031595)
0.8 2.4 GO:0000813 ESCRT I complex(GO:0000813) ESCRT complex(GO:0036452)
0.7 14.9 GO:0046930 pore complex(GO:0046930)
0.7 6.6 GO:0045178 basal part of cell(GO:0045178)
0.7 8.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.7 3.4 GO:0071797 LUBAC complex(GO:0071797)
0.6 21.3 GO:0060170 ciliary membrane(GO:0060170)
0.6 38.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.6 659.8 GO:0005739 mitochondrion(GO:0005739)
0.6 7.6 GO:0035102 PRC1 complex(GO:0035102)
0.6 8.5 GO:0000421 autophagosome membrane(GO:0000421)
0.6 8.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.6 83.1 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.5 115.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.5 22.2 GO:0045171 intercellular bridge(GO:0045171)
0.5 6.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.5 0.9 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.4 14.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.4 13.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.4 2.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.4 4.9 GO:0030057 desmosome(GO:0030057) messenger ribonucleoprotein complex(GO:1990124)
0.4 24.9 GO:0055037 recycling endosome(GO:0055037)
0.3 8.8 GO:0035861 site of double-strand break(GO:0035861)
0.3 5.1 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.3 372.4 GO:0005615 extracellular space(GO:0005615)
0.3 2.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.3 1.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.3 3.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.3 10.5 GO:0042383 sarcolemma(GO:0042383)
0.2 35.9 GO:0016324 apical plasma membrane(GO:0016324)
0.2 60.6 GO:0061695 transferase complex, transferring phosphorus-containing groups(GO:0061695)
0.2 10.5 GO:0005901 caveola(GO:0005901)
0.2 43.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.2 1.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 2.8 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.2 2.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.2 3.6 GO:0022624 proteasome accessory complex(GO:0022624)
0.2 55.3 GO:0031967 organelle envelope(GO:0031967)
0.2 2.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.2 0.2 GO:0035838 growing cell tip(GO:0035838)
0.2 0.9 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 0.8 GO:0031415 NatA complex(GO:0031415)
0.1 2.2 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 5.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 3.6 GO:0005844 polysome(GO:0005844)
0.1 0.4 GO:0016528 sarcoplasm(GO:0016528)
0.1 1.9 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.6 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 2.5 GO:0005801 cis-Golgi network(GO:0005801)
0.1 2.5 GO:0031012 extracellular matrix(GO:0031012)
0.1 215.3 GO:0005576 extracellular region(GO:0005576)
0.1 0.7 GO:0005682 U5 snRNP(GO:0005682)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
79.2 237.7 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
63.4 190.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
43.9 175.7 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
41.6 124.9 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
33.4 301.0 GO:0032052 bile acid binding(GO:0032052)
32.7 130.7 GO:0004743 pyruvate kinase activity(GO:0004743)
29.3 205.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
28.8 86.4 GO:0004736 pyruvate carboxylase activity(GO:0004736)
28.6 114.4 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
26.1 78.4 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
25.6 128.0 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
25.5 1047.5 GO:0070330 aromatase activity(GO:0070330)
25.5 127.3 GO:0016841 ammonia-lyase activity(GO:0016841)
23.9 143.4 GO:0048039 ubiquinone binding(GO:0048039)
23.5 70.6 GO:0070012 oligopeptidase activity(GO:0070012)
23.2 69.7 GO:0031714 C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
22.9 68.6 GO:0004167 dopachrome isomerase activity(GO:0004167)
21.6 86.4 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
20.9 83.6 GO:0008940 nitrate reductase activity(GO:0008940)
20.7 124.0 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
20.4 163.0 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
18.9 94.7 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
18.4 18.4 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
17.7 53.2 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
17.3 51.9 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
16.5 82.6 GO:0030283 testosterone dehydrogenase [NAD(P)] activity(GO:0030283)
16.3 114.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
15.0 104.9 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
14.6 58.6 GO:0004903 growth hormone receptor activity(GO:0004903)
14.4 43.1 GO:0004925 prolactin receptor activity(GO:0004925)
14.4 86.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
13.9 292.3 GO:0034185 apolipoprotein binding(GO:0034185)
13.9 41.7 GO:0004159 dihydrouracil dehydrogenase (NAD+) activity(GO:0004159) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
13.4 40.3 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
12.9 129.0 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
12.9 51.4 GO:0004967 glucagon receptor activity(GO:0004967)
12.4 37.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
12.3 61.7 GO:0031849 olfactory receptor binding(GO:0031849)
12.0 47.9 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
11.9 190.7 GO:0035497 cAMP response element binding(GO:0035497)
11.1 44.6 GO:0015350 methotrexate transporter activity(GO:0015350)
11.1 155.6 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
10.9 32.7 GO:0016748 succinyltransferase activity(GO:0016748)
10.9 43.5 GO:0047619 acylcarnitine hydrolase activity(GO:0047619)
10.6 53.1 GO:0070404 NADH binding(GO:0070404)
10.6 31.7 GO:0004046 aminoacylase activity(GO:0004046) catalase activity(GO:0004096)
10.2 71.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
10.2 40.9 GO:0016019 peptidoglycan receptor activity(GO:0016019)
10.2 81.4 GO:0008172 S-methyltransferase activity(GO:0008172)
9.9 119.0 GO:0070008 serine-type exopeptidase activity(GO:0070008)
9.9 29.6 GO:0015254 glycerol channel activity(GO:0015254)
9.1 27.4 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
9.1 36.4 GO:0034618 arginine binding(GO:0034618)
8.7 43.7 GO:0070891 lipoteichoic acid binding(GO:0070891)
8.5 110.9 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
8.5 25.6 GO:0004924 oncostatin-M receptor activity(GO:0004924)
8.4 167.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
8.2 115.4 GO:0042301 phosphate ion binding(GO:0042301)
8.0 31.9 GO:0035727 lysophosphatidic acid binding(GO:0035727)
7.7 15.4 GO:0004075 biotin carboxylase activity(GO:0004075)
7.5 29.9 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
7.4 14.9 GO:0015168 polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168)
7.4 22.3 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
7.4 29.7 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
7.3 36.6 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
6.9 34.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
6.8 33.8 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
6.6 52.4 GO:0015232 heme transporter activity(GO:0015232)
6.5 58.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
6.5 155.3 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
6.4 25.6 GO:0015137 citrate transmembrane transporter activity(GO:0015137)
6.1 30.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
6.0 12.0 GO:0034056 estrogen response element binding(GO:0034056)
6.0 83.6 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
5.9 35.2 GO:0070051 fibrinogen binding(GO:0070051)
5.7 62.2 GO:0001846 opsonin binding(GO:0001846)
5.6 33.5 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
5.5 27.7 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
5.4 43.6 GO:0003996 acyl-CoA ligase activity(GO:0003996)
5.4 43.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
5.4 21.5 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
5.3 21.3 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
5.3 16.0 GO:0004040 amidase activity(GO:0004040)
5.2 47.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
4.9 68.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
4.9 77.6 GO:0043176 amine binding(GO:0043176)
4.8 43.6 GO:0004887 thyroid hormone receptor activity(GO:0004887)
4.8 105.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
4.8 14.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
4.6 13.8 GO:0043546 molybdopterin cofactor binding(GO:0043546)
4.6 27.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
4.6 13.8 GO:0017168 5-oxoprolinase (ATP-hydrolyzing) activity(GO:0017168)
4.5 49.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
4.5 18.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
4.5 35.9 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
4.5 13.5 GO:0019960 C-X3-C chemokine binding(GO:0019960)
4.5 13.4 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
4.4 17.7 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
4.4 39.4 GO:0015250 water channel activity(GO:0015250)
4.3 17.1 GO:0016160 amylase activity(GO:0016160)
4.0 271.1 GO:0038024 cargo receptor activity(GO:0038024)
4.0 20.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
3.7 22.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
3.6 28.5 GO:0016151 nickel cation binding(GO:0016151)
3.4 27.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
3.4 57.7 GO:0016854 racemase and epimerase activity(GO:0016854)
3.4 23.7 GO:0008430 selenium binding(GO:0008430)
3.2 12.8 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
3.1 15.4 GO:0019770 IgG receptor activity(GO:0019770)
3.0 39.6 GO:0098919 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
3.0 26.8 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
2.9 17.6 GO:0004126 cytidine deaminase activity(GO:0004126)
2.9 177.3 GO:0009055 electron carrier activity(GO:0009055)
2.9 17.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
2.8 22.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
2.8 11.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
2.8 19.8 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
2.8 67.7 GO:0019865 immunoglobulin binding(GO:0019865)
2.8 14.0 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
2.8 13.9 GO:0051373 FATZ binding(GO:0051373)
2.8 41.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
2.7 8.1 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
2.7 541.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
2.7 10.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
2.7 8.0 GO:0005128 erythropoietin receptor binding(GO:0005128)
2.6 10.4 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
2.6 10.4 GO:0008265 Mo-molybdopterin cofactor sulfurase activity(GO:0008265)
2.6 10.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
2.6 25.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
2.5 20.4 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
2.5 37.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
2.5 14.9 GO:0016803 ether hydrolase activity(GO:0016803)
2.5 22.4 GO:0008494 translation activator activity(GO:0008494)
2.5 14.8 GO:0036374 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
2.4 16.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
2.3 91.2 GO:0016831 carboxy-lyase activity(GO:0016831)
2.3 41.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
2.3 27.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
2.3 9.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
2.2 15.7 GO:1901612 cardiolipin binding(GO:1901612)
2.2 17.8 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
2.2 68.5 GO:0004623 phospholipase A2 activity(GO:0004623)
2.2 33.0 GO:0051787 misfolded protein binding(GO:0051787)
2.1 99.8 GO:0005507 copper ion binding(GO:0005507)
2.0 124.4 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
2.0 62.5 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
1.9 9.7 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.9 9.4 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
1.9 9.4 GO:0070728 leucine binding(GO:0070728)
1.8 14.8 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
1.7 5.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
1.7 32.2 GO:0019200 carbohydrate kinase activity(GO:0019200)
1.7 8.4 GO:0015204 urea transmembrane transporter activity(GO:0015204)
1.6 13.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
1.6 6.5 GO:0032190 acrosin binding(GO:0032190)
1.6 37.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
1.6 11.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
1.6 27.1 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
1.6 11.1 GO:0031014 troponin T binding(GO:0031014)
1.5 4.5 GO:0004911 interleukin-2 receptor activity(GO:0004911)
1.5 8.8 GO:0000150 recombinase activity(GO:0000150)
1.4 33.3 GO:0070001 aspartic-type peptidase activity(GO:0070001)
1.4 4.2 GO:0070698 nodal binding(GO:0038100) type I activin receptor binding(GO:0070698)
1.3 5.3 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
1.3 22.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
1.3 3.9 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
1.3 8.9 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
1.2 18.6 GO:0043522 leucine zipper domain binding(GO:0043522)
1.2 38.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
1.2 22.9 GO:0008199 ferric iron binding(GO:0008199)
1.2 10.4 GO:0071837 HMG box domain binding(GO:0071837)
1.1 122.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
1.1 8.4 GO:0071253 connexin binding(GO:0071253)
1.0 3.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
1.0 11.1 GO:0005000 vasopressin receptor activity(GO:0005000)
1.0 12.9 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
1.0 11.9 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
1.0 7.9 GO:0034046 poly(G) binding(GO:0034046)
1.0 49.2 GO:0008146 sulfotransferase activity(GO:0008146)
1.0 6.7 GO:0097322 7SK snRNA binding(GO:0097322)
1.0 13.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
1.0 20.2 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.9 4.7 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.9 13.1 GO:0015926 glucosidase activity(GO:0015926)
0.9 13.0 GO:0033038 bitter taste receptor activity(GO:0033038)
0.9 17.6 GO:0017081 chloride channel regulator activity(GO:0017081)
0.9 17.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.9 5.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.9 4.5 GO:0046527 glucosyltransferase activity(GO:0046527)
0.9 5.4 GO:0019203 carbohydrate phosphatase activity(GO:0019203)
0.9 2.6 GO:0008169 C-methyltransferase activity(GO:0008169)
0.9 10.4 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.8 11.0 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.8 52.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.8 4.8 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.8 3.2 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.8 147.3 GO:0008168 methyltransferase activity(GO:0008168)
0.8 6.8 GO:0019808 polyamine binding(GO:0019808)
0.8 19.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.7 10.3 GO:0010181 FMN binding(GO:0010181)
0.7 6.6 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.7 7.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.7 1.4 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.7 17.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.7 5.6 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.7 11.9 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.7 9.1 GO:0015643 toxic substance binding(GO:0015643)
0.7 14.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.7 7.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.6 22.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.6 32.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.6 47.4 GO:0051213 dioxygenase activity(GO:0051213)
0.6 3.0 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.6 14.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.6 2.3 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.6 3.4 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.6 11.8 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.6 4.5 GO:0019966 interleukin-1 binding(GO:0019966)
0.5 63.2 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.5 2.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.5 2.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.5 10.2 GO:0017166 vinculin binding(GO:0017166)
0.5 1.5 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.5 55.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.5 8.6 GO:0005501 retinoid binding(GO:0005501)
0.4 2.5 GO:0050897 cobalt ion binding(GO:0050897)
0.4 2.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.4 9.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.4 18.0 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.4 1.6 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.4 7.6 GO:0032183 SUMO binding(GO:0032183)
0.4 14.8 GO:0000049 tRNA binding(GO:0000049)
0.4 2.9 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.4 7.8 GO:0003951 NAD+ kinase activity(GO:0003951)
0.4 2.5 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.4 4.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.4 5.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.3 10.1 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.3 5.6 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.3 11.7 GO:0019213 deacetylase activity(GO:0019213)
0.3 1.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.3 2.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 21.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.3 9.3 GO:0005109 frizzled binding(GO:0005109)
0.3 8.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.3 2.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3 4.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 2.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.3 5.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 5.0 GO:0005504 fatty acid binding(GO:0005504)
0.3 3.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.3 1.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 6.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 1.5 GO:0031419 cobalamin binding(GO:0031419)
0.2 11.1 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.2 2.7 GO:0048018 receptor agonist activity(GO:0048018)
0.2 73.9 GO:0005549 odorant binding(GO:0005549)
0.2 0.5 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 4.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 8.8 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.1 9.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 0.7 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.6 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 1.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.6 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 1.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.3 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322) oligopeptide transmembrane transporter activity(GO:0035673)
0.1 5.7 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 2.7 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 0.6 GO:0035198 miRNA binding(GO:0035198)
0.1 1.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 7.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 2.1 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 1.3 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.1 1.5 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.1 1.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 51.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 1.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 1.9 GO:0051087 chaperone binding(GO:0051087)
0.0 3.3 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
10.6 581.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
5.3 163.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
4.7 121.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
3.1 134.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
2.7 98.9 PID IGF1 PATHWAY IGF1 pathway
2.6 62.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
2.5 599.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
2.4 112.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
2.2 4.5 PID S1P S1P2 PATHWAY S1P2 pathway
2.1 159.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
1.8 55.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
1.8 35.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
1.3 15.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
1.2 43.8 PID IL6 7 PATHWAY IL6-mediated signaling events
1.1 18.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
1.0 49.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.9 30.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.9 20.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.8 8.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.8 28.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.6 11.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.6 9.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.6 9.2 SIG CHEMOTAXIS Genes related to chemotaxis
0.4 25.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.4 16.0 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.3 14.9 PID FOXO PATHWAY FoxO family signaling
0.3 5.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.3 9.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.3 6.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 10.1 PID AP1 PATHWAY AP-1 transcription factor network
0.2 3.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 15.4 PID CMYB PATHWAY C-MYB transcription factor network
0.2 1.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 2.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 12.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 2.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.2 1.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.2 13.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 3.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 7.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 3.1 PID E2F PATHWAY E2F transcription factor network
0.1 1.5 PID IL1 PATHWAY IL1-mediated signaling events
0.1 2.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
29.2 292.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
27.3 463.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
19.5 58.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
19.5 273.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
16.8 101.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
15.7 188.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
14.6 160.8 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
14.4 187.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
11.0 87.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
10.4 134.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
9.9 118.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
8.7 8.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
8.7 87.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
8.5 153.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
8.4 50.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
8.3 149.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
8.1 137.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
7.1 205.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
7.1 141.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
7.1 155.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
7.0 83.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
6.8 109.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
5.9 229.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
5.4 353.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
5.4 32.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
5.4 112.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
5.0 69.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
4.8 100.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
3.9 38.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
3.8 65.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
3.8 101.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
3.2 371.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
3.2 35.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
2.9 17.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
2.6 18.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
2.6 389.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
2.5 152.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
2.3 63.1 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
2.3 38.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
2.2 30.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
2.1 63.9 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
2.0 32.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
1.8 74.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
1.8 58.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
1.7 13.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
1.6 19.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
1.3 2.7 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
1.3 53.6 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
1.3 20.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
1.2 61.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
1.2 23.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
1.2 16.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
1.2 40.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
1.1 17.9 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
1.1 7.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
1.1 20.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
1.0 9.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
1.0 10.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
1.0 12.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
1.0 38.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.9 6.4 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.9 18.0 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.8 31.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.7 8.8 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.6 8.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.6 12.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.6 9.2 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.6 7.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.5 8.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.5 13.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.5 13.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.5 9.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5 11.3 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.4 5.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.4 5.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.4 2.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.3 11.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.3 6.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.2 3.1 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.2 10.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 3.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 4.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 2.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 4.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 1.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 5.3 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.1 2.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.4 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.1 1.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions