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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Pou4f1_Pou6f1

Z-value: 0.94

Motif logo

Transcription factors associated with Pou4f1_Pou6f1

Gene Symbol Gene ID Gene Info
ENSRNOG00000060662 POU class 4 homeobox 1
ENSRNOG00000004595 POU class 6 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou4f1rn6_v1_chr15_-_88622413_886224130.371.3e-11Click!
Pou6f1rn6_v1_chr7_-_142210738_1422107380.256.0e-06Click!

Activity profile of Pou4f1_Pou6f1 motif

Sorted Z-values of Pou4f1_Pou6f1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_133400485 47.56 ENSRNOT00000006219
contactin 1
chr3_-_26056818 37.22 ENSRNOT00000044209
LDL receptor related protein 1B
chr14_+_60764409 33.95 ENSRNOT00000005168
leucine-rich repeat LGI family, member 2
chr1_-_93949187 33.12 ENSRNOT00000018956
zinc finger protein 536
chr6_+_64789940 32.40 ENSRNOT00000085979
ENSRNOT00000059739
ENSRNOT00000051908
ENSRNOT00000082793
ENSRNOT00000078583
ENSRNOT00000091677
ENSRNOT00000093241
neuronal cell adhesion molecule
chr13_+_57243877 31.18 ENSRNOT00000083693
potassium sodium-activated channel subfamily T member 2
chrX_-_142164220 29.54 ENSRNOT00000064780
fibroblast growth factor 13
chr5_+_57947716 29.28 ENSRNOT00000067657
dynein, axonemal, intermediate chain 1
chr6_-_23291568 28.95 ENSRNOT00000085708
CAP-GLY domain containing linker protein family, member 4
chr2_-_196402106 28.36 ENSRNOT00000028664
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11
chr17_-_43675934 25.52 ENSRNOT00000081345
histone cluster 1 H1 family member t
chr14_+_39964588 25.36 ENSRNOT00000003240
gamma-aminobutyric acid type A receptor gamma 1 subunit
chr10_-_93675991 25.33 ENSRNOT00000090662
membrane associated ring-CH-type finger 10
chr7_-_50278842 24.06 ENSRNOT00000088950
synaptotagmin 1
chr16_-_81880502 23.58 ENSRNOT00000079096
MCF.2 cell line derived transforming sequence-like
chr1_-_280015358 23.03 ENSRNOT00000024548
heat shock protein family A (Hsp70) member 12A
chr10_+_86303727 21.62 ENSRNOT00000037752
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr16_+_39827749 21.59 ENSRNOT00000074885
WD repeat domain 17
chr11_+_66316606 20.78 ENSRNOT00000041715
syntaxin binding protein 5-like
chr10_-_27366665 20.60 ENSRNOT00000004725
gamma-aminobutyric acid type A receptor alpha1 subunit
chr1_-_25839198 20.33 ENSRNOT00000090388
ENSRNOT00000092757
ENSRNOT00000042072
triadin
chr2_-_35104963 20.10 ENSRNOT00000018058
regulator of G-protein signaling 7-binding protein
chr3_+_53563194 20.04 ENSRNOT00000048300
xin actin-binding repeat containing 2
chrX_+_53053609 19.65 ENSRNOT00000058357
dystrophin
chr15_-_76789298 19.61 ENSRNOT00000077853

chr2_-_104461863 19.20 ENSRNOT00000016953
corticotropin releasing hormone
chr8_-_80631873 18.67 ENSRNOT00000091661
ENSRNOT00000080662
unc-13 homolog C
chr7_+_44009069 18.25 ENSRNOT00000005523
MGAT4 family, member C
chr7_-_124929025 17.79 ENSRNOT00000015447
EF-hand calcium binding domain 6
chr10_-_47725172 17.71 ENSRNOT00000003228
ring finger protein 112
chr16_-_18643309 17.45 ENSRNOT00000031680
DPY30 domain containing 2
chr3_+_177188044 17.30 ENSRNOT00000022073
transcription elongation factor A2
chr4_+_22859622 17.18 ENSRNOT00000073501
ENSRNOT00000068410
ADAM metallopeptidase domain 22
chr15_+_1054937 17.05 ENSRNOT00000008154

chr9_+_73334618 16.98 ENSRNOT00000092717
microtubule-associated protein 2
chr5_-_57947183 16.86 ENSRNOT00000060642
family with sequence similarity 219, member A
chr9_-_66845403 16.50 ENSRNOT00000041546
islet cell autoantigen 1-like
chr2_+_127625683 15.95 ENSRNOT00000015474
heat shock protein 4-like
chr3_+_94848823 15.81 ENSRNOT00000041362
coiled-coil domain containing 73
chr2_-_247446882 14.65 ENSRNOT00000021963
bone morphogenetic protein receptor type 1B
chr2_+_242882306 14.59 ENSRNOT00000013661
DNA-damage-inducible transcript 4-like
chr12_-_35979193 14.52 ENSRNOT00000071104
transmembrane protein 132B
chr16_+_7292096 14.49 ENSRNOT00000025606
troponin C1, slow skeletal and cardiac type
chr19_+_20607507 14.43 ENSRNOT00000000011
cerebellin 1 precursor
chr20_-_25826658 14.02 ENSRNOT00000057950
ENSRNOT00000084660
catenin alpha 3
chr11_+_76147205 13.95 ENSRNOT00000071586
fibroblast growth factor 12
chr11_+_82194657 13.75 ENSRNOT00000002445
ets variant 5
chr6_-_23542928 13.65 ENSRNOT00000083858
speedy/RINGO cell cycle regulator family member A
chr2_+_69415057 13.55 ENSRNOT00000013152
cadherin 10
chr14_+_114152472 13.38 ENSRNOT00000042965
reticulon 4
chr15_-_104168564 13.30 ENSRNOT00000093385
ENSRNOT00000038596
DAZ interacting zinc finger protein 1
chr11_+_36851038 13.08 ENSRNOT00000002221
ENSRNOT00000061047
Purkinje cell protein 4
chr3_-_66885085 13.02 ENSRNOT00000084299
ENSRNOT00000090547
phosphodiesterase 1A
chr2_-_19808937 12.81 ENSRNOT00000044237
ATPase H+ transporting accessory protein 1 like
chr1_-_173764246 12.29 ENSRNOT00000019690
ENSRNOT00000086944
LIM domain only 1
chr1_+_137799185 11.97 ENSRNOT00000083590
ENSRNOT00000092778
ATP/GTP binding protein-like 1
chr6_+_7900972 11.68 ENSRNOT00000006953
ENSRNOT00000068030
dynein cytoplasmic 2 light intermediate chain 1
chr14_-_55081551 11.64 ENSRNOT00000049245
protocadherin 7
chr1_-_246010594 11.62 ENSRNOT00000023762
regulatory factor X3
chrX_-_56765893 11.54 ENSRNOT00000076283
interleukin 1 receptor accessory protein-like 1
chr6_+_27328406 11.35 ENSRNOT00000091159
ENSRNOT00000044278
otoferlin
chr3_-_150064438 11.33 ENSRNOT00000086933
E2F transcription factor 1
chr18_+_30581530 11.28 ENSRNOT00000048166
protocadherin beta 20
chr15_+_87886783 11.21 ENSRNOT00000065710
SLAIN motif family, member 1
chr8_-_8524643 11.06 ENSRNOT00000009418
contactin 5
chr14_-_43143973 10.97 ENSRNOT00000003248
ubiquitin C-terminal hydrolase L1
chr14_-_62595854 10.87 ENSRNOT00000003024
Yip1 domain family, member 7
chr9_-_105376935 10.76 ENSRNOT00000043386
solute carrier organic anion transporter family, member 6d1
chr16_-_54628458 10.75 ENSRNOT00000042587
ADAM metallopeptidase domain 24
chr5_+_103479767 10.56 ENSRNOT00000008999
SH3 domain-containing GRB2-like 2
chr9_+_24095751 10.40 ENSRNOT00000018177
phosphoglycerate kinase 2
chr13_+_42220251 10.31 ENSRNOT00000078185

chr10_-_21265026 10.30 ENSRNOT00000011922
teneurin transmembrane protein 2
chr7_+_141346398 10.27 ENSRNOT00000077175
acid sensing ion channel subunit 1
chrX_+_159158194 10.15 ENSRNOT00000043820
ENSRNOT00000001169
ENSRNOT00000083502
four and a half LIM domains 1
chr3_-_158328881 10.11 ENSRNOT00000044466
protein tyrosine phosphatase, receptor type, T
chr2_+_260039651 10.10 ENSRNOT00000073873
ankyrin repeat and SOCS box-containing 17
chr14_-_41786084 9.97 ENSRNOT00000059439
glutaredoxin and cysteine rich domain containing 1
chr1_+_211582077 9.97 ENSRNOT00000023619
PWWP domain containing 2B
chr18_+_54108493 9.82 ENSRNOT00000029239
similar to DD1
chr12_+_38368693 9.80 ENSRNOT00000083261
CAP-GLY domain containing linker protein 1
chr3_+_161121697 9.77 ENSRNOT00000036020
WAP four-disulfide core domain 10A
chr15_-_90175802 9.72 ENSRNOT00000013342
sprouty RTK signaling antagonist 2
chr14_-_28967980 9.67 ENSRNOT00000048175
adhesion G protein-coupled receptor L3
chr2_-_84531192 9.64 ENSRNOT00000065312
ENSRNOT00000090540
rhophilin associated tail protein 1-like
chr18_+_30562178 9.53 ENSRNOT00000040998
protocadherin beta-16-like
chr8_-_96547568 9.35 ENSRNOT00000078343
similar to RIKEN cDNA 4930579C12 gene
chr8_+_122076759 9.29 ENSRNOT00000012545
cytoplasmic linker associated protein 2
chr2_+_92574038 9.15 ENSRNOT00000089422
GTPase activating protein testicular GAP1
chr3_+_148510779 9.11 ENSRNOT00000012156
XK related 7
chr3_-_147188929 9.01 ENSRNOT00000055455
RAD21 cohesin complex component like 1
chr5_+_27326762 8.99 ENSRNOT00000066191
RUNX1 translocation partner 1
chr1_-_16203838 8.98 ENSRNOT00000018556
ENSRNOT00000078586
phosphodiesterase 7B
chr10_+_53778662 8.97 ENSRNOT00000045718
myosin heavy chain 2
chr17_+_60287203 8.96 ENSRNOT00000025585
armadillo repeat containing 4
chr14_+_7171613 8.93 ENSRNOT00000081600
kelch-like family member 8
chr8_+_100260049 8.76 ENSRNOT00000011090

chr7_+_11582984 8.63 ENSRNOT00000026893
G protein subunit gamma 7
chr9_-_114282799 8.60 ENSRNOT00000090539
uncharacterized LOC102555328
chr2_-_137153551 8.54 ENSRNOT00000083443

chr11_+_32440237 8.44 ENSRNOT00000040844
potassium voltage-gated channel subfamily E regulatory subunit 2
chr15_-_80713153 8.44 ENSRNOT00000063800
kelch-like family member 1
chr4_-_135069970 8.36 ENSRNOT00000008221
contactin 3
chr12_+_41486076 8.07 ENSRNOT00000057242
RBPJ interacting and tubulin associated 1
chr7_+_123043503 7.98 ENSRNOT00000026258
ENSRNOT00000086355
TEF, PAR bZIP transcription factor
chr2_-_219262901 7.96 ENSRNOT00000037068
G-protein coupled receptor 88
chr6_-_95934296 7.93 ENSRNOT00000034338
SIX homeobox 1
chr5_-_156689415 7.81 ENSRNOT00000083474
PTEN induced putative kinase 1
chr7_+_15785410 7.77 ENSRNOT00000082664
ENSRNOT00000073235
zinc finger protein 955A
chr16_+_29674793 7.76 ENSRNOT00000059724
annexin A10
chr2_-_59181863 7.71 ENSRNOT00000079636
sperm flagellar 2
chr3_-_160922341 7.63 ENSRNOT00000029206
TP53 target 5
chr9_-_104870382 7.56 ENSRNOT00000084398
solute carrier organic anion transporter family, member 6d1
chr6_-_25507073 7.53 ENSRNOT00000061176
phospholipase B1
chr4_-_41212072 7.46 ENSRNOT00000085596
protein phosphatase 1, regulatory subunit 3A
chr14_-_108372068 7.46 ENSRNOT00000088116
ENSRNOT00000091143
ENSRNOT00000085886
similar to KIAA1841 protein
chr1_-_145931583 7.45 ENSRNOT00000016433
cilia and flagella associated protein 161
chr9_+_77320726 7.41 ENSRNOT00000068450
sperm associated antigen 16
chr19_-_41349681 7.25 ENSRNOT00000080694
ENSRNOT00000059147
Hydin, axonemal central pair apparatus protein
chr6_+_101603319 7.25 ENSRNOT00000030470
gephyrin
chr14_+_71533063 7.24 ENSRNOT00000004231
prominin 1
chr1_-_227392054 7.12 ENSRNOT00000054806
membrane-spanning 4-domains, subfamily A, member 13, pseudogene 1
chr14_+_84231639 7.06 ENSRNOT00000066362
galactose-3-O-sulfotransferase 1
chr9_+_47281961 7.02 ENSRNOT00000065234
solute carrier family 9 member A4
chr19_+_25143428 6.82 ENSRNOT00000007535
paralemmin 3
chr8_+_55504359 6.79 ENSRNOT00000059086
BTG anti-proliferation factor 4
chr2_-_186232292 6.73 ENSRNOT00000087088
doublecortin-like kinase 2
chr1_+_101603222 6.71 ENSRNOT00000033278
izumo sperm-egg fusion 1
chr1_+_172752416 6.63 ENSRNOT00000087448
olfactory receptor 268
chr3_+_154395187 6.59 ENSRNOT00000050810
V-set and transmembrane domain containing 2 like
chr10_+_46722109 6.55 ENSRNOT00000032685
dynein regulatory complex subunit 3
chr1_-_227486976 6.51 ENSRNOT00000035812
membrane spanning 4-domains A14
chr7_-_68549763 6.39 ENSRNOT00000078014
solute carrier family 16 member 7
chr19_-_22194740 6.35 ENSRNOT00000086187
phosphorylase kinase regulatory subunit beta
chr14_-_92077088 6.32 ENSRNOT00000085175
growth factor receptor bound protein 10
chr10_-_89187474 6.31 ENSRNOT00000064931
up-regulated during skeletal muscle growth 5 homolog (mouse)
chr2_+_113984646 6.27 ENSRNOT00000016799
TRAF2 and NCK interacting kinase
chr7_-_120380200 6.24 ENSRNOT00000014878
similar to RIKEN cDNA 1700088E04
chr8_+_107882219 6.22 ENSRNOT00000019902
DAZ interacting zinc finger protein 1-like
chr10_-_57671080 6.22 ENSRNOT00000082511
hypothetical protein LOC691995
chr1_+_162890475 6.14 ENSRNOT00000034886
glycerophosphodiester phosphodiesterase domain containing 4
chr10_-_36322356 6.06 ENSRNOT00000000248
zinc finger protein 354C
chr3_+_112428395 6.06 ENSRNOT00000079109
ENSRNOT00000048141
StAR-related lipid transfer domain containing 9
chr15_-_2731462 6.03 ENSRNOT00000018023
sterile alpha motif domain containing 8
chr4_-_163095614 5.97 ENSRNOT00000088759
similar to CD69 antigen (p60, early T-cell activation antigen)
chr10_+_53818818 5.92 ENSRNOT00000057260
myosin heavy chain 8
chr9_-_32868371 5.85 ENSRNOT00000038369
similar to chromosome 9 open reading frame 79
chr7_-_106695570 5.78 ENSRNOT00000083517
HERV-H LTR-associating 1
chr5_-_12563429 5.74 ENSRNOT00000059625
suppression of tumorigenicity 18
chr8_+_71216178 5.70 ENSRNOT00000021372
ornithine decarboxylase antizyme 2
chr7_+_25808419 5.69 ENSRNOT00000091571
regulatory factor X4
chr18_+_29987206 5.64 ENSRNOT00000027383
protocadherin alpha 4
chr1_-_205030567 5.45 ENSRNOT00000023404
C-terminal binding protein 2
chr17_+_77176716 5.44 ENSRNOT00000083342
ENSRNOT00000024162
optineurin
chr1_+_5448958 5.41 ENSRNOT00000061930
epilepsy, progressive myoclonus type 2A
chr16_-_20641908 5.26 ENSRNOT00000026846
elongation factor for RNA polymerase II
chr17_-_79085076 5.24 ENSRNOT00000057851
family with sequence similarity 171, member A1
chr18_-_38374 5.23 ENSRNOT00000036914
vomeronasal 2 receptor, 75
chr1_-_100669684 5.22 ENSRNOT00000091760
myosin heavy chain 14
chr5_-_6186329 5.19 ENSRNOT00000012610
sulfatase 1
chr15_+_3938075 5.17 ENSRNOT00000065644
calcium/calmodulin-dependent protein kinase II gamma
chr18_+_30424814 5.14 ENSRNOT00000073425
protocadherin beta 7
chr15_-_35153804 5.12 ENSRNOT00000050660
granzyme N
chr2_-_88763733 5.07 ENSRNOT00000059424
similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr10_+_31508512 5.00 ENSRNOT00000031580
family with sequence similarity 71, member B
chr13_-_74923402 4.95 ENSRNOT00000033324
RAS protein activator like 2
chr14_-_1505085 4.92 ENSRNOT00000090361
uncharacterized LOC102554799
chrX_-_74968405 4.89 ENSRNOT00000035653
similar to KIAA2022 protein
chr2_-_132301073 4.88 ENSRNOT00000058288
similar to GTPase activating protein testicular GAP1
chr9_+_53013413 4.79 ENSRNOT00000005313
ankyrin and armadillo repeat containing
chr3_+_100786862 4.75 ENSRNOT00000080190
brain-derived neurotrophic factor
chr20_-_34684418 4.74 ENSRNOT00000087220
centrosomal protein 85-like
chr7_-_122926336 4.72 ENSRNOT00000000205
chondroadherin-like
chr18_+_30509393 4.65 ENSRNOT00000043846
protocadherin beta 12
chr9_+_101268905 4.65 ENSRNOT00000023270
olfactory receptor 178
chr2_+_92549479 4.59 ENSRNOT00000082912
GTPase activating protein testicular GAP1
chrX_+_63542191 4.56 ENSRNOT00000073955
apolipoprotein O
chr13_-_47916185 4.54 ENSRNOT00000087793
dual specificity tyrosine phosphorylation regulated kinase 3
chr17_+_49417067 4.49 ENSRNOT00000090024
POU domain, class 6, transcription factor 2
chr9_-_60672246 4.46 ENSRNOT00000017761
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr1_-_49844547 4.42 ENSRNOT00000086127
ENSRNOT00000077423
ENSRNOT00000089439
ENSRNOT00000090521

chr19_+_43163129 4.36 ENSRNOT00000073721
C-type lectin domain family 18, member A
chrX_-_122062799 4.29 ENSRNOT00000086852
predicted gene 4907
chr8_+_49077053 4.28 ENSRNOT00000087922
intraflagellar transport 46
chr5_-_153840178 4.27 ENSRNOT00000025075
NIPA-like domain containing 3
chr9_-_88816898 4.27 ENSRNOT00000083667
solute carrier family 19 member 3
chr8_+_99680406 4.21 ENSRNOT00000042834
phospholipid scramblase 1-like
chr20_+_17750744 4.15 ENSRNOT00000000745
similar to RIKEN cDNA 1700049L16
chr20_-_776472 4.10 ENSRNOT00000049250
olfactory receptor 1690
chr9_+_24066303 3.99 ENSRNOT00000018163
cysteine-rich secretory protein 3
chr3_-_160561741 3.93 ENSRNOT00000018364
potassium voltage-gated channel, modifier subfamily S, member 1
chr1_+_1702696 3.92 ENSRNOT00000019181
LDL receptor related protein 11
chr1_-_66321642 3.91 ENSRNOT00000074234

chr10_-_36323055 3.88 ENSRNOT00000081026
zinc finger protein 354C
chr3_+_102456938 3.85 ENSRNOT00000051827
olfactory receptor 748
chr15_+_4850122 3.84 ENSRNOT00000071133
G protein subunit gamma 2
chr6_+_102215603 3.80 ENSRNOT00000014257
pleckstrin homology, MyTH4 and FERM domain containing H1
chr16_+_90325304 3.78 ENSRNOT00000057310
solute carrier family 10 member 2
chr1_-_48797631 3.76 ENSRNOT00000082958
1-acylglycerol-3-phosphate O-acyltransferase 4
chr1_-_47477524 3.72 ENSRNOT00000067916
radial spoke 3 homolog

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou4f1_Pou6f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.8 20.3 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
6.5 19.6 GO:0021629 muscle attachment(GO:0016203) olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
4.8 14.5 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
4.8 19.2 GO:0070093 hormone-mediated apoptotic signaling pathway(GO:0008628) positive regulation of cortisol secretion(GO:0051464) negative regulation of glucagon secretion(GO:0070093)
4.2 29.5 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
3.9 11.6 GO:2000078 glandular epithelial cell maturation(GO:0002071) positive regulation of type B pancreatic cell development(GO:2000078)
3.7 33.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
3.6 32.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
3.3 13.1 GO:1904009 cellular response to monosodium glutamate(GO:1904009)
3.1 21.6 GO:0007621 negative regulation of female receptivity(GO:0007621)
3.1 12.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
2.8 8.4 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
2.8 14.0 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
2.8 13.8 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
2.7 10.7 GO:0060468 prevention of polyspermy(GO:0060468)
2.6 7.9 GO:2000729 response to 3,3',5-triiodo-L-thyronine(GO:1905242) cellular response to 3,3',5-triiodo-L-thyronine(GO:1905243) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
2.5 7.5 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
2.5 7.4 GO:0051012 microtubule sliding(GO:0051012)
2.4 7.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
2.3 11.3 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
2.2 13.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
2.2 28.4 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
2.1 38.2 GO:0036158 outer dynein arm assembly(GO:0036158)
2.1 14.7 GO:0022605 oogenesis stage(GO:0022605)
2.0 12.0 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
2.0 9.8 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
1.9 5.7 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
1.9 18.6 GO:0007412 axon target recognition(GO:0007412)
1.8 7.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
1.8 14.0 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
1.7 17.5 GO:0006348 chromatin silencing at telomere(GO:0006348)
1.7 5.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
1.7 24.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
1.7 18.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
1.7 11.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
1.6 8.2 GO:0098970 establishment of synaptic specificity at neuromuscular junction(GO:0007529) gamma-aminobutyric acid receptor clustering(GO:0097112) receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
1.6 9.7 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
1.6 8.0 GO:0061743 motor learning(GO:0061743)
1.6 7.8 GO:1903384 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) maintenance of protein location in mitochondrion(GO:0072656) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
1.5 20.6 GO:0071420 cellular response to histamine(GO:0071420)
1.5 10.3 GO:0050915 sensory perception of sour taste(GO:0050915)
1.4 11.5 GO:0097105 presynaptic membrane assembly(GO:0097105)
1.4 4.3 GO:0071934 thiamine transmembrane transport(GO:0071934)
1.3 10.6 GO:0016191 synaptic vesicle uncoating(GO:0016191)
1.3 6.4 GO:1901475 pyruvate transmembrane transport(GO:1901475)
1.2 8.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
1.2 14.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.2 3.5 GO:0016476 regulation of embryonic cell shape(GO:0016476)
1.1 5.7 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
1.1 4.5 GO:0035617 stress granule disassembly(GO:0035617)
1.1 3.3 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
1.1 5.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
1.1 3.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
1.0 9.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.0 7.1 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
1.0 13.0 GO:0046069 cGMP catabolic process(GO:0046069)
1.0 5.9 GO:0030049 muscle filament sliding(GO:0030049)
1.0 4.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
1.0 2.9 GO:0090249 cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
0.9 7.5 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.9 10.3 GO:0097264 self proteolysis(GO:0097264)
0.9 25.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.9 2.7 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.9 5.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.9 11.4 GO:0016082 synaptic vesicle priming(GO:0016082)
0.9 32.2 GO:0035036 sperm-egg recognition(GO:0035036)
0.9 47.6 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.8 9.0 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.8 2.4 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.8 4.7 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.8 10.0 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.8 3.1 GO:0070086 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086)
0.8 6.8 GO:0008063 Toll signaling pathway(GO:0008063)
0.7 23.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.7 9.0 GO:0001778 plasma membrane repair(GO:0001778)
0.7 5.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.7 5.4 GO:0046959 habituation(GO:0046959)
0.6 6.0 GO:2000303 regulation of ceramide biosynthetic process(GO:2000303)
0.6 7.7 GO:0007288 sperm axoneme assembly(GO:0007288)
0.6 7.0 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.6 5.2 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.5 17.0 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.5 9.7 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.5 66.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.4 6.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.4 3.1 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.4 8.6 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.4 3.4 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.4 9.6 GO:0048240 sperm capacitation(GO:0048240)
0.4 3.8 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.4 13.3 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.4 1.2 GO:0016107 sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
0.4 10.2 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.4 3.6 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.4 20.8 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.4 12.8 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.4 2.3 GO:0008078 mesodermal cell migration(GO:0008078) establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.4 13.7 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.4 3.6 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.4 3.9 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.3 1.4 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.3 1.0 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.3 4.6 GO:0042407 cristae formation(GO:0042407)
0.3 4.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.3 20.0 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.3 2.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.3 8.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.3 2.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.3 25.6 GO:0008344 adult locomotory behavior(GO:0008344)
0.3 4.5 GO:0021860 pyramidal neuron development(GO:0021860)
0.3 3.2 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.3 1.5 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.2 3.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.2 2.4 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.2 3.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.2 3.6 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.2 3.9 GO:0009414 response to water deprivation(GO:0009414)
0.2 7.6 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.2 1.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.2 1.6 GO:0007097 nuclear migration(GO:0007097)
0.2 5.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.2 2.3 GO:1902358 oxalate transport(GO:0019532) sulfate transmembrane transport(GO:1902358)
0.2 16.0 GO:0006986 response to unfolded protein(GO:0006986)
0.2 10.4 GO:0030317 sperm motility(GO:0030317)
0.2 1.7 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.2 3.3 GO:0048520 positive regulation of behavior(GO:0048520)
0.2 1.5 GO:0007635 chemosensory behavior(GO:0007635)
0.2 3.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 8.0 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 1.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 2.7 GO:0046130 purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.1 4.3 GO:0042073 intraciliary transport(GO:0042073)
0.1 3.6 GO:0071450 cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451)
0.1 5.1 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.1 16.5 GO:0007286 spermatid development(GO:0007286)
0.1 4.2 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 4.9 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.1 0.3 GO:0019046 viral latency(GO:0019042) release from viral latency(GO:0019046)
0.1 2.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 20.4 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 4.9 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.1 0.7 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1 1.1 GO:0046599 regulation of centriole replication(GO:0046599)
0.1 2.5 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 1.4 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 3.9 GO:0046850 regulation of bone remodeling(GO:0046850)
0.1 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.8 GO:0006108 malate metabolic process(GO:0006108)
0.1 8.2 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.1 1.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 2.1 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 2.8 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 3.5 GO:0005977 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 1.3 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 2.3 GO:0060443 mammary gland morphogenesis(GO:0060443)
0.0 0.6 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 2.9 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.5 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.0 1.6 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.8 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.3 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 2.1 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:0009750 response to fructose(GO:0009750)
0.0 3.4 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 0.4 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.7 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 1.2 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.8 20.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
4.9 29.3 GO:0036157 outer dynein arm(GO:0036157)
4.0 24.1 GO:0042584 chromaffin granule membrane(GO:0042584)
3.6 14.5 GO:1990584 cardiac Troponin complex(GO:1990584)
2.9 14.7 GO:1990716 axonemal central apparatus(GO:1990716)
2.3 18.7 GO:0044305 calyx of Held(GO:0044305)
1.9 11.3 GO:0035189 Rb-E2F complex(GO:0035189)
1.9 17.0 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
1.9 7.5 GO:0071914 prominosome(GO:0071914)
1.3 9.3 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
1.3 5.3 GO:0035363 histone locus body(GO:0035363)
1.3 5.2 GO:0097513 myosin II filament(GO:0097513)
1.3 9.0 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
1.2 32.4 GO:0043194 axon initial segment(GO:0043194)
1.2 3.6 GO:1990923 PET complex(GO:1990923)
1.1 11.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
1.1 9.0 GO:0005826 actomyosin contractile ring(GO:0005826)
1.1 12.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
1.1 19.2 GO:0043196 varicosity(GO:0043196)
1.1 3.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
1.0 9.8 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
1.0 4.9 GO:0016035 zeta DNA polymerase complex(GO:0016035)
1.0 17.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.9 20.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.9 7.8 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.8 13.1 GO:0005883 neurofilament(GO:0005883)
0.8 6.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.7 14.0 GO:0005916 fascia adherens(GO:0005916)
0.7 25.4 GO:0034707 chloride channel complex(GO:0034707)
0.7 10.0 GO:0060091 kinocilium(GO:0060091)
0.7 7.7 GO:0002177 manchette(GO:0002177)
0.7 10.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.7 3.5 GO:0005940 septin ring(GO:0005940)
0.7 4.6 GO:0061617 MICOS complex(GO:0061617)
0.6 3.2 GO:0043159 acrosomal matrix(GO:0043159)
0.6 8.0 GO:0097539 ciliary transition fiber(GO:0097539)
0.6 29.5 GO:0014704 intercalated disc(GO:0014704)
0.6 10.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.5 58.7 GO:0031225 anchored component of membrane(GO:0031225)
0.5 5.9 GO:0032982 myosin filament(GO:0032982)
0.5 3.4 GO:0000322 storage vacuole(GO:0000322)
0.5 13.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.5 8.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.5 3.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.5 43.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.4 3.6 GO:0031595 nuclear proteasome complex(GO:0031595)
0.4 11.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.4 5.5 GO:0097470 ribbon synapse(GO:0097470)
0.4 3.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.3 8.2 GO:0060077 inhibitory synapse(GO:0060077)
0.3 3.1 GO:0000813 ESCRT I complex(GO:0000813)
0.3 4.0 GO:0042581 specific granule(GO:0042581)
0.3 9.0 GO:0097546 ciliary base(GO:0097546)
0.3 2.7 GO:0033263 CORVET complex(GO:0033263)
0.3 12.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 4.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.3 11.0 GO:1904115 axon cytoplasm(GO:1904115)
0.3 1.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.3 1.1 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.3 6.7 GO:0002080 acrosomal membrane(GO:0002080)
0.3 25.5 GO:0000786 nucleosome(GO:0000786)
0.3 4.4 GO:0030061 mitochondrial crista(GO:0030061)
0.3 23.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.3 2.3 GO:0031209 SCAR complex(GO:0031209)
0.2 6.3 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.2 5.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 15.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 4.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.2 1.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.2 16.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 15.5 GO:0005814 centriole(GO:0005814)
0.2 0.5 GO:1990423 Dsl1p complex(GO:0070939) RZZ complex(GO:1990423)
0.1 2.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 4.5 GO:0072686 mitotic spindle(GO:0072686)
0.1 13.2 GO:0030018 Z disc(GO:0030018)
0.1 6.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 21.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 6.5 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 2.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 3.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 2.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 5.4 GO:0005844 polysome(GO:0005844)
0.1 1.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 9.6 GO:0031514 motile cilium(GO:0031514)
0.1 8.1 GO:0005923 bicellular tight junction(GO:0005923)
0.1 8.2 GO:0030424 axon(GO:0030424)
0.1 5.3 GO:0031526 brush border membrane(GO:0031526)
0.1 5.4 GO:0005776 autophagosome(GO:0005776)
0.1 2.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 17.1 GO:0016324 apical plasma membrane(GO:0016324)
0.1 3.8 GO:0042641 actomyosin(GO:0042641)
0.1 1.5 GO:0002102 podosome(GO:0002102)
0.0 21.7 GO:0043025 neuronal cell body(GO:0043025)
0.0 3.9 GO:0005795 Golgi stack(GO:0005795)
0.0 17.9 GO:0045202 synapse(GO:0045202)
0.0 2.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.2 GO:0005643 nuclear pore(GO:0005643)
0.0 16.3 GO:0005815 microtubule organizing center(GO:0005815)
0.0 3.7 GO:0005874 microtubule(GO:0005874)
0.0 2.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.5 GO:0043235 receptor complex(GO:0043235)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 21.6 GO:0031752 D5 dopamine receptor binding(GO:0031752)
5.9 53.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
4.8 24.1 GO:0030348 syntaxin-3 binding(GO:0030348)
4.8 19.2 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
4.1 33.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
4.1 20.6 GO:0008503 benzodiazepine receptor activity(GO:0008503) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
3.5 10.4 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
3.4 10.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
3.3 13.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
2.9 11.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
2.7 11.0 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
2.5 7.5 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
2.4 14.5 GO:0031013 troponin I binding(GO:0031013)
2.1 18.7 GO:0019992 diacylglycerol binding(GO:0019992)
2.1 8.2 GO:0008940 nitrate reductase activity(GO:0008940)
2.0 45.9 GO:0002162 dystroglycan binding(GO:0002162)
1.9 5.7 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
1.8 14.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
1.8 5.4 GO:2001070 starch binding(GO:2001070)
1.8 7.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
1.5 25.4 GO:0050811 GABA receptor binding(GO:0050811)
1.4 4.3 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) uptake transmembrane transporter activity(GO:0015563)
1.3 5.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.3 6.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.2 6.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.2 6.0 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
1.1 5.4 GO:0001155 TFIIIA-class transcription factor binding(GO:0001155)
1.1 31.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
1.0 7.8 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
1.0 11.5 GO:0019966 interleukin-1 binding(GO:0019966)
1.0 7.6 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.9 8.4 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.9 43.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.9 11.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.9 12.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.8 10.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.8 21.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.8 6.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.7 7.0 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.7 17.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.6 12.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.6 3.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.6 3.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.6 9.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.6 3.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.6 8.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.6 15.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.5 4.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.5 13.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.5 11.1 GO:0000146 microfilament motor activity(GO:0000146)
0.5 1.4 GO:0019807 aspartoacylase activity(GO:0019807)
0.4 1.2 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
0.4 4.4 GO:0005000 vasopressin receptor activity(GO:0005000)
0.4 2.9 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.4 19.5 GO:0042805 actinin binding(GO:0042805)
0.3 3.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.3 2.4 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.3 1.4 GO:0036004 GAF domain binding(GO:0036004)
0.3 1.0 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.3 3.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.3 9.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.3 1.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.3 4.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.3 1.1 GO:0019002 GMP binding(GO:0019002)
0.3 7.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 3.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 1.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 4.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 2.7 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.2 2.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 25.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 4.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 5.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.2 21.3 GO:0003774 motor activity(GO:0003774)
0.2 6.3 GO:0005158 insulin receptor binding(GO:0005158)
0.2 2.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 23.2 GO:0044325 ion channel binding(GO:0044325)
0.2 2.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 2.8 GO:0016595 glutamate binding(GO:0016595)
0.2 5.5 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 1.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 12.2 GO:0019905 syntaxin binding(GO:0019905)
0.1 13.1 GO:0005516 calmodulin binding(GO:0005516)
0.1 2.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 4.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 3.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 2.9 GO:0070064 proline-rich region binding(GO:0070064)
0.1 10.9 GO:0001948 glycoprotein binding(GO:0001948)
0.1 0.5 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 0.6 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.7 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 5.1 GO:0015297 antiporter activity(GO:0015297)
0.1 1.0 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 2.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.8 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.1 4.7 GO:0005518 collagen binding(GO:0005518)
0.1 1.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 36.8 GO:0005509 calcium ion binding(GO:0005509)
0.1 16.6 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 6.2 GO:0043130 ubiquitin binding(GO:0043130)
0.1 1.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 6.3 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.1 13.8 GO:0005096 GTPase activator activity(GO:0005096)
0.1 3.1 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 3.9 GO:0051219 phosphoprotein binding(GO:0051219)
0.1 3.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 12.5 GO:0045296 cadherin binding(GO:0045296)
0.0 2.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 26.2 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.1 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 2.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 47.6 PID NOTCH PATHWAY Notch signaling pathway
0.6 22.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.6 26.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.5 20.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.4 32.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.3 17.0 PID LKB1 PATHWAY LKB1 signaling events
0.3 9.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.3 6.3 PID IGF1 PATHWAY IGF1 pathway
0.3 14.7 PID BMP PATHWAY BMP receptor signaling
0.3 9.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.3 7.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.3 11.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.3 3.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 3.3 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.2 6.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.2 5.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 5.5 PID TNF PATHWAY TNF receptor signaling pathway
0.2 1.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 31.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 4.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 31.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 5.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 1.5 PID ARF 3PATHWAY Arf1 pathway
0.1 2.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 9.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.6 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 3.6 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
1.7 24.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
1.6 47.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
1.2 20.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
1.1 18.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
1.0 40.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.9 32.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.9 24.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.9 11.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.8 9.7 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.6 10.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.5 12.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.5 6.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.5 14.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.5 13.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.5 3.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.5 13.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.5 6.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.4 6.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.3 2.4 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.3 3.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 3.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 13.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 5.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 16.3 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.2 5.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.2 7.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 9.3 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.2 2.4 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.2 2.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 11.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 11.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 3.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 10.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 3.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 9.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling