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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Pou3f2

Z-value: 0.78

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Transcription factors associated with Pou3f2

Gene Symbol Gene ID Gene Info
Pou3f2
ENSRNOG00000006908 POU class 3 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou3f2rn6_v1_chr5_-_36683356_366833560.434.6e-16Click!

Activity profile of Pou3f2 motif

Sorted Z-values of Pou3f2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_106998623 42.84 ENSRNOT00000022383
Slc17a6
solute carrier family 17 member 6
chr9_-_32019205 33.44 ENSRNOT00000016194
Adgrb3
adhesion G protein-coupled receptor B3
chr4_-_159287193 30.81 ENSRNOT00000080139
Kcna6
potassium voltage-gated channel subfamily A member 6
chr4_+_21462779 29.45 ENSRNOT00000089747
Grm3
glutamate metabotropic receptor 3
chr17_+_53231343 26.79 ENSRNOT00000021703
Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr4_+_35279063 25.34 ENSRNOT00000011833
Nxph1
neurexophilin 1
chr6_-_23291568 25.04 ENSRNOT00000085708
Clip4
CAP-GLY domain containing linker protein family, member 4
chr5_-_130085838 24.59 ENSRNOT00000035252
Elavl4
ELAV like RNA binding protein 4
chr4_-_117268178 23.31 ENSRNOT00000043201
ENSRNOT00000084049
Fbxo41
F-box protein 41
chr10_+_1920529 23.27 ENSRNOT00000072296
A630010A05Rik
RIKEN cDNA A630010A05 gene
chr11_-_11213821 19.67 ENSRNOT00000093706
Robo2
roundabout guidance receptor 2
chr4_-_17594598 19.57 ENSRNOT00000008936
Sema3e
semaphorin 3E
chr13_+_24823488 19.26 ENSRNOT00000019907
Cdh20
cadherin 20
chr7_+_64768742 18.90 ENSRNOT00000005545
Grip1
glutamate receptor interacting protein 1
chr17_-_8925503 18.49 ENSRNOT00000015163
Catsper3
cation channel, sperm associated 3
chrX_-_56765893 18.43 ENSRNOT00000076283
Il1rapl1
interleukin 1 receptor accessory protein-like 1
chr11_-_11214141 17.85 ENSRNOT00000065748
Robo2
roundabout guidance receptor 2
chr5_-_172424081 16.41 ENSRNOT00000019096
Plch2
phospholipase C, eta 2
chr3_-_111994337 15.56 ENSRNOT00000030502
Pla2g4e
phospholipase A2, group IVE
chr13_-_47916185 15.20 ENSRNOT00000087793
Dyrk3
dual specificity tyrosine phosphorylation regulated kinase 3
chr17_+_43423111 14.94 ENSRNOT00000022630
Hist1h2ba
histone cluster 1 H2B family member a
chr5_+_146656049 14.23 ENSRNOT00000036029
Csmd2
CUB and Sushi multiple domains 2
chr2_+_3662763 13.93 ENSRNOT00000017828
Mctp1
multiple C2 and transmembrane domain containing 1
chr1_+_162890475 13.54 ENSRNOT00000034886
Gdpd4
glycerophosphodiester phosphodiesterase domain containing 4
chr8_+_28454962 12.66 ENSRNOT00000051573
Spata19
spermatogenesis associated 19
chr14_-_28536260 12.43 ENSRNOT00000059942
Adgrl3
adhesion G protein-coupled receptor L3
chr16_-_32753278 12.21 ENSRNOT00000015759
Mfap3l
microfibrillar-associated protein 3-like
chr15_-_71779033 12.12 ENSRNOT00000017765
Pcdh20
protocadherin 20
chr10_-_93679974 12.09 ENSRNOT00000009316
March10
membrane associated ring-CH-type finger 10
chr17_-_43422846 11.98 ENSRNOT00000050526
Hist1h2aa
histone cluster 1 H2A family member a
chr15_+_40665041 11.34 ENSRNOT00000018300
Amer2
APC membrane recruitment protein 2
chr7_-_132143470 11.20 ENSRNOT00000038946
ENSRNOT00000044092
ENSRNOT00000066528
ENSRNOT00000045553
ENSRNOT00000046744
ENSRNOT00000055742
Kif21a
kinesin family member 21A
chr6_+_126874193 11.05 ENSRNOT00000011775
Unc79
unc-79 homolog (C. elegans)
chr18_+_51492196 10.87 ENSRNOT00000020570
Gramd3
GRAM domain containing 3
chr19_-_56037077 10.63 ENSRNOT00000021968
Spata2L
spermatogenesis associated 2-like
chr12_+_18931477 10.50 ENSRNOT00000077087
Spry3
sprouty RTK signaling antagonist 3
chr15_-_5667328 10.34 ENSRNOT00000061522
AABR07016976.1

chr13_+_93751759 10.28 ENSRNOT00000065706
Wdr64
WD repeat domain 64
chr10_+_69737328 9.92 ENSRNOT00000055999
ENSRNOT00000076773
Tmem132e
transmembrane protein 132E
chr7_+_34402738 9.89 ENSRNOT00000030985
Ccdc38
coiled-coil domain containing 38
chr6_+_78567970 9.86 ENSRNOT00000032743
Ttc6
tetratricopeptide repeat domain 6
chr2_+_27630285 9.54 ENSRNOT00000032960
Ankrd31
ankyrin repeat domain 31
chr10_-_56426012 9.47 ENSRNOT00000092506
ENSRNOT00000084068
LOC497938
similar to RIKEN cDNA 4933402P03
chr16_+_52169450 9.30 ENSRNOT00000019474
Triml1
tripartite motif family-like 1
chr15_+_58016238 8.99 ENSRNOT00000075786
Kctd4
potassium channel tetramerization domain containing 4
chr7_-_27552078 8.91 ENSRNOT00000059538
Stab2
stabilin 2
chr5_-_115387377 8.63 ENSRNOT00000036030
ENSRNOT00000077492
RGD1560146
similar to hypothetical protein MGC34837
chr3_+_138770574 8.53 ENSRNOT00000012510
ENSRNOT00000066986
Dtd1
D-tyrosyl-tRNA deacylase 1
chr9_-_110225486 8.24 ENSRNOT00000045096
Efna5
ephrin A5
chr5_-_73494030 8.09 ENSRNOT00000022291
Actl7b
actin-like 7b
chr1_+_146976975 7.57 ENSRNOT00000071895
LOC100366231
X-linked lymphocyte-regulated 5C-like
chr17_+_59714657 7.50 ENSRNOT00000035675
RGD1560860
similar to ankyrin repeat domain 26
chrX_-_122062799 7.49 ENSRNOT00000086852
Gm4907
predicted gene 4907
chr3_+_54253949 7.29 ENSRNOT00000010018
B3galt1
Beta-1,3-galactosyltransferase 1
chr5_-_76261198 7.28 ENSRNOT00000087380
AABR07048387.1

chr18_-_81682206 7.28 ENSRNOT00000058219
LOC100359752
hypothetical protein LOC100359752
chr9_+_10941613 7.24 ENSRNOT00000070794
Sema6b
semaphorin 6B
chr10_+_17327275 7.10 ENSRNOT00000005486
Ubtd2
ubiquitin domain containing 2
chr13_-_74520634 6.86 ENSRNOT00000077169
Ralgps2
Ral GEF with PH domain and SH3 binding motif 2
chr6_+_9790422 6.80 ENSRNOT00000020959
Prkce
protein kinase C, epsilon
chr3_+_128155069 6.67 ENSRNOT00000051184
ENSRNOT00000006389
Plcb1
phospholipase C beta 1
chr1_-_67094567 6.37 ENSRNOT00000073583
AABR07071871.1

chr2_-_132301073 6.25 ENSRNOT00000058288
RGD1563562
similar to GTPase activating protein testicular GAP1
chr6_-_95796502 6.18 ENSRNOT00000041409
Six6os1
Six6 opposite strand transcript 1
chr4_+_8066907 6.18 ENSRNOT00000080811
Srpk2
SRSF protein kinase 2
chr9_+_119542328 6.16 ENSRNOT00000082005
Lpin2
lipin 2
chr20_+_21316826 5.97 ENSRNOT00000000785
RGD1306739
similar to RIKEN cDNA 1700040L02
chrX_+_122313470 5.80 ENSRNOT00000018322
RGD1566387
similar to hypothetical protein
chr1_+_89149998 5.51 ENSRNOT00000056742
LOC688924
hypothetical protein LOC688924
chr6_+_91532467 5.51 ENSRNOT00000082500
ENSRNOT00000064668
Klhdc1
kelch domain containing 1
chr2_-_216348194 5.51 ENSRNOT00000087839
LOC103689940
pancreatic alpha-amylase-like
chr10_-_52290657 5.44 ENSRNOT00000005293
Map2k4
mitogen activated protein kinase kinase 4
chr10_-_72472675 5.43 ENSRNOT00000081649
Usp32
ubiquitin specific peptidase 32
chr20_+_1197746 5.37 ENSRNOT00000045794
Olr1710
olfactory receptor 1710
chr8_-_114010277 5.34 ENSRNOT00000045087
Atp2c1
ATPase secretory pathway Ca2+ transporting 1
chr13_+_67545430 5.29 ENSRNOT00000003405
Pdc
phosducin
chr5_+_154868534 5.09 ENSRNOT00000091442
Luzp1
leucine zipper protein 1
chr15_+_18941431 5.05 ENSRNOT00000092092
AABR07017236.1

chr2_-_173836854 4.97 ENSRNOT00000074278
Wdr49
WD repeat domain 49
chr7_-_68523364 4.96 ENSRNOT00000077670
Slc16a7
solute carrier family 16 member 7
chr6_+_73553210 4.87 ENSRNOT00000006562
Akap6
A-kinase anchoring protein 6
chr12_+_10063117 4.82 ENSRNOT00000044038
Usp12
ubiquitin specific peptidase 12
chr15_-_83442008 4.72 ENSRNOT00000039400
Mzt1
mitotic spindle organizing protein 1
chr10_-_70181708 4.39 ENSRNOT00000076598
Rffl
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr2_-_232178533 4.25 ENSRNOT00000082173
ENSRNOT00000055607
Ap1ar
adaptor-related protein complex 1 associated regulatory protein
chr10_-_58771908 4.25 ENSRNOT00000018808
RGD1304728
similar to 4933427D14Rik protein
chrX_-_61151601 4.05 ENSRNOT00000004132
Mageb4
melanoma antigen family B, 4
chr2_+_138489364 3.97 ENSRNOT00000042248
LOC103691563
60S ribosomal protein L31 pseudogene
chrX_-_915953 3.92 ENSRNOT00000075264
Spaca5
sperm acrosome associated 5
chr4_+_8066737 3.89 ENSRNOT00000063994
Srpk2
SRSF protein kinase 2
chr7_-_122926336 3.88 ENSRNOT00000000205
Chadl
chondroadherin-like
chr6_-_146470456 3.86 ENSRNOT00000018479
RGD1560883
similar to KIAA0825 protein
chr19_+_43163129 3.86 ENSRNOT00000073721
Clec18a
C-type lectin domain family 18, member A
chr1_+_266844480 3.72 ENSRNOT00000027482
Taf5
TATA-box binding protein associated factor 5
chr2_-_142235066 3.44 ENSRNOT00000018385
Cog6
component of oligomeric golgi complex 6
chr2_-_123851854 3.38 ENSRNOT00000023327
Il2
interleukin 2
chr15_+_83442144 3.33 ENSRNOT00000039344
Bora
bora, aurora kinase A activator
chr7_-_116712387 3.19 ENSRNOT00000088064
Top1mt
topoisomerase (DNA) I, mitochondrial
chr20_+_1172867 3.05 ENSRNOT00000041189
Olr1708
olfactory receptor 1708
chr5_+_60850852 3.00 ENSRNOT00000016720
Trmt10b
tRNA methyltransferase 10B
chr4_+_154215250 2.80 ENSRNOT00000072465
Mug2
murinoglobulin 2
chr4_-_70628470 2.80 ENSRNOT00000029319
Try5
trypsin 5
chr3_+_94549180 2.59 ENSRNOT00000016318
Cstf3
cleavage stimulation factor subunit 3
chr16_+_23475351 2.43 ENSRNOT00000068177
Psd3
pleckstrin and Sec7 domain containing 3
chr4_-_121822781 2.41 ENSRNOT00000072082
Vom1r95
vomeronasal 1 receptor 95
chr3_-_48451650 2.37 ENSRNOT00000007356
Gcg
glucagon
chr8_+_79054237 2.30 ENSRNOT00000077613
Mns1
meiosis-specific nuclear structural 1
chr13_+_80125391 2.26 ENSRNOT00000044190
Mir199a2
microRNA 199a-2
chr4_-_125929002 2.17 ENSRNOT00000083271
Magi1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr16_+_10250404 2.12 ENSRNOT00000087037
ENSRNOT00000081183
Gdf10
growth differentiation factor 10
chr7_-_124020574 2.11 ENSRNOT00000055988
Poldip3
DNA polymerase delta interacting protein 3
chr2_-_5577369 2.04 ENSRNOT00000093420
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr3_+_97723901 2.01 ENSRNOT00000080416
Mpped2
metallophosphoesterase domain containing 2
chr3_+_75936795 1.99 ENSRNOT00000007603
Olr588
olfactory receptor 588
chrX_+_113510621 1.96 ENSRNOT00000025912
Nxt2
nuclear transport factor 2-like export factor 2
chr10_-_87153982 1.60 ENSRNOT00000014414
Krt222
keratin 222
chr1_+_247107397 1.59 ENSRNOT00000082290
Cdc37l1
cell division cycle 37-like 1
chr17_-_27451832 1.55 ENSRNOT00000084417
Riok1
RIO kinase 1
chr4_+_121760773 1.52 ENSRNOT00000087069
Vom1r92
vomeronasal 1 receptor 92
chr11_+_45401403 1.51 ENSRNOT00000002240
Tbc1d23
TBC1 domain family, member 23
chr17_+_8135251 1.51 ENSRNOT00000016982
Trpc7
transient receptor potential cation channel, subfamily C, member 7
chr7_+_143897014 1.46 ENSRNOT00000017314
Espl1
extra spindle pole bodies like 1, separase
chr2_+_193627243 1.45 ENSRNOT00000082934
AABR07012331.1

chr7_+_66624512 1.30 ENSRNOT00000079410
Usp15
ubiquitin specific peptidase 15
chr16_-_79793619 1.27 ENSRNOT00000073971
Arhgef10
Rho guanine nucleotide exchange factor 10
chr1_-_170175350 1.23 ENSRNOT00000023349
Olr201
olfactory receptor 201
chr11_+_67451549 1.15 ENSRNOT00000042777
Stfa2l2
stefin A2-like 2
chr5_+_64053946 1.13 ENSRNOT00000011622
Invs
inversin
chr3_+_94530586 1.08 ENSRNOT00000067860
Cstf3
cleavage stimulation factor subunit 3
chr13_-_73055631 1.04 ENSRNOT00000081892
Xpr1
xenotropic and polytropic retrovirus receptor 1
chrX_-_31759161 0.99 ENSRNOT00000041515
Asb9
ankyrin repeat and SOCS box-containing 9
chr8_-_69164758 0.82 ENSRNOT00000013933
Map2k1
mitogen activated protein kinase kinase 1
chr8_+_87630916 0.82 ENSRNOT00000016428
Myo6
myosin VI
chr13_+_29839867 0.79 ENSRNOT00000090623
AABR07020537.1

chrX_-_159244879 0.78 ENSRNOT00000030445
Map7d3
MAP7 domain containing 3
chr1_+_230056710 0.74 ENSRNOT00000073539
Olr357
olfactory receptor 357
chr2_+_150344307 0.74 ENSRNOT00000072617
Aadacl2
arylacetamide deacetylase-like 2
chr11_+_66932614 0.66 ENSRNOT00000003189
Slc15a2
solute carrier family 15 member 2
chr10_-_86645529 0.64 ENSRNOT00000011947
Med24
mediator complex subunit 24
chr20_+_37876650 0.62 ENSRNOT00000001054
Gja1
gap junction protein, alpha 1
chr18_+_40087823 0.59 ENSRNOT00000041763
AABR07031947.1

chr1_+_229480184 0.58 ENSRNOT00000044115
Olr387
olfactory receptor 387
chrX_-_76925195 0.57 ENSRNOT00000087977
Atrx
ATRX, chromatin remodeler
chr20_+_1124169 0.41 ENSRNOT00000072544
LOC100910894
olfactory receptor 14J1-like
chr7_+_17956631 0.40 ENSRNOT00000064298
Vom1r106
vomeronasal 1 receptor 106
chr1_-_76722965 0.36 ENSRNOT00000052129
LOC100912485
alcohol sulfotransferase-like
chr10_+_71332803 0.35 ENSRNOT00000087428
Synrg
synergin, gamma
chr1_+_64740487 0.25 ENSRNOT00000081213
LOC103691005
zinc finger protein 679-like
chr11_-_45688560 0.19 ENSRNOT00000081508
Olr1536
olfactory receptor 1536
chr11_+_43329700 0.11 ENSRNOT00000060892
Olr1540
olfactory receptor 1540
chr5_-_128333805 0.09 ENSRNOT00000037523
Zfyve9
zinc finger FYVE-type containing 9
chr1_+_189432604 0.09 ENSRNOT00000034610
Acsm4
acyl-CoA synthetase medium-chain family member 4
chr1_-_77750960 0.06 ENSRNOT00000018858
Crx
cone-rod homeobox
chr10_+_83856280 0.05 ENSRNOT00000008964
Snf8
SNF8, ESCRT-II complex subunit
chr1_+_127604197 0.02 ENSRNOT00000018463
Lins1
lines homolog 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou3f2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.5 37.5 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
6.7 33.4 GO:0061743 motor learning(GO:0061743)
4.8 42.8 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
3.0 15.2 GO:0035617 stress granule disassembly(GO:0035617)
2.7 29.4 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
2.5 14.9 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
2.2 6.7 GO:0035723 interleukin-12-mediated signaling pathway(GO:0035722) interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-12(GO:0071349) cellular response to interleukin-15(GO:0071350) regulation of monocyte extravasation(GO:2000437)
2.0 10.1 GO:0035063 nuclear speck organization(GO:0035063)
1.8 18.4 GO:0097105 presynaptic membrane assembly(GO:0097105)
1.8 5.3 GO:0032472 Golgi calcium ion transport(GO:0032472)
1.7 6.9 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
1.7 6.8 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
1.6 4.7 GO:0033566 gamma-tubulin complex localization(GO:0033566)
1.4 5.4 GO:0072709 cellular response to sorbitol(GO:0072709)
1.2 6.2 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
1.2 4.9 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
1.0 5.0 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.8 3.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.8 12.5 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading(GO:1900025)
0.7 4.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.7 18.5 GO:0048240 sperm capacitation(GO:0048240)
0.7 5.3 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.6 12.4 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.6 11.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.6 19.6 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.6 2.4 GO:1903576 response to L-arginine(GO:1903576)
0.5 7.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.5 5.1 GO:0001842 neural fold formation(GO:0001842)
0.4 8.5 GO:0006450 regulation of translational fidelity(GO:0006450)
0.4 15.6 GO:0009395 phospholipid catabolic process(GO:0009395)
0.3 24.6 GO:0042220 response to cocaine(GO:0042220)
0.3 1.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.3 0.6 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.2 1.1 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.2 0.7 GO:0042938 dipeptide transport(GO:0042938)
0.2 31.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 0.8 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.2 6.2 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.2 3.9 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.2 2.0 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 1.6 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.2 2.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 3.3 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 4.3 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 2.3 GO:0070986 left/right axis specification(GO:0070986)
0.1 16.4 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.1 3.0 GO:0030488 tRNA methylation(GO:0030488)
0.1 1.0 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 2.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 21.3 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 10.3 GO:0016579 protein deubiquitination(GO:0016579)
0.1 3.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 7.3 GO:0006342 chromatin silencing(GO:0006342)
0.1 1.5 GO:0006828 manganese ion transport(GO:0006828)
0.1 7.4 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1 1.5 GO:0051307 meiotic chromosome separation(GO:0051307)
0.1 1.3 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.8 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 7.6 GO:0007286 spermatid development(GO:0007286)
0.1 2.1 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 14.5 GO:0016358 dendrite development(GO:0016358)
0.0 11.2 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.4 GO:0006265 DNA topological change(GO:0006265)
0.0 3.3 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 28.3 GO:0016567 protein ubiquitination(GO:0016567)
0.0 10.8 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.8 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.0 GO:0043328 regulation of multivesicular body size(GO:0010796) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 1.6 GO:0050821 protein stabilization(GO:0050821)
0.0 0.1 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 18.5 GO:0036128 CatSper complex(GO:0036128)
2.5 24.6 GO:0042788 polysomal ribosome(GO:0042788)
2.2 33.4 GO:0043083 synaptic cleft(GO:0043083)
1.8 42.8 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.6 4.9 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
1.6 4.7 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) gamma-tubulin small complex(GO:0008275)
1.4 29.4 GO:0097449 astrocyte projection(GO:0097449)
1.1 4.4 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
1.1 37.5 GO:0030673 axolemma(GO:0030673)
0.5 8.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.5 6.2 GO:0000801 central element(GO:0000801)
0.4 1.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.3 15.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.3 30.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.3 3.6 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.2 3.4 GO:0017119 Golgi transport complex(GO:0017119)
0.2 3.3 GO:0072687 meiotic spindle(GO:0072687)
0.2 22.3 GO:0000786 nucleosome(GO:0000786)
0.2 6.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 11.2 GO:0005871 kinesin complex(GO:0005871)
0.1 1.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 4.3 GO:0034451 centriolar satellite(GO:0034451)
0.1 2.1 GO:0000346 transcription export complex(GO:0000346)
0.1 16.9 GO:0055037 recycling endosome(GO:0055037)
0.1 5.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 3.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 3.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 30.5 GO:0030424 axon(GO:0030424)
0.0 1.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 20.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 6.7 GO:0043209 myelin sheath(GO:0043209)
0.0 1.5 GO:0072686 mitotic spindle(GO:0072686)
0.0 2.3 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 11.2 GO:0005813 centrosome(GO:0005813)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
9.8 29.4 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
3.1 37.5 GO:0008046 axon guidance receptor activity(GO:0008046)
2.6 41.1 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
2.3 13.5 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
2.2 26.8 GO:0030215 semaphorin receptor binding(GO:0030215)
1.8 5.5 GO:0004556 alpha-amylase activity(GO:0004556)
1.7 6.8 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
1.5 18.4 GO:0019966 interleukin-1 binding(GO:0019966)
1.5 7.3 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
1.3 30.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
1.0 8.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
1.0 5.0 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.9 18.9 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.9 24.6 GO:0017091 AU-rich element binding(GO:0017091)
0.7 15.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.7 4.3 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.7 8.9 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.7 3.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.7 5.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.6 3.0 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.6 8.5 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.5 4.9 GO:0043495 protein anchor(GO:0043495)
0.5 5.3 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.5 6.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.5 15.6 GO:0004623 phospholipase A2 activity(GO:0004623)
0.4 10.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.4 6.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.3 18.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.3 3.9 GO:0003796 lysozyme activity(GO:0003796)
0.3 1.0 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.3 2.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 7.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2 0.7 GO:0042895 antibiotic transporter activity(GO:0042895)
0.2 39.0 GO:0016874 ligase activity(GO:0016874)
0.2 3.9 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 11.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 11.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 4.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 11.2 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.6 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 2.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 23.1 GO:0005096 GTPase activator activity(GO:0005096)
0.1 4.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 4.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 7.1 GO:0043130 ubiquitin binding(GO:0043130)
0.1 2.2 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 0.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 24.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 3.9 GO:0005518 collagen binding(GO:0005518)
0.0 1.3 GO:0019894 kinesin binding(GO:0019894)
0.0 21.3 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.6 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.8 GO:0003774 motor activity(GO:0003774)
0.0 2.4 GO:0005179 hormone activity(GO:0005179)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.3 6.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.3 15.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 8.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 6.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 21.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.4 PID IL27 PATHWAY IL27-mediated signaling events
0.1 3.3 PID PLK1 PATHWAY PLK1 signaling events
0.1 3.8 PID TNF PATHWAY TNF receptor signaling pathway
0.1 2.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 29.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.1 19.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.7 37.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.7 41.7 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.7 8.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.7 6.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.6 30.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.6 14.9 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.4 6.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.3 8.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 5.1 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.2 3.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.2 2.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 1.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 5.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 3.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 3.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 0.8 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 2.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway