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GSE53960: rat RNA-Seq transcriptomic Bodymap
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Results for Pou2f3
Z-value: 1.19
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Transcription factors associated with Pou2f3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Pou2f3 | rn6_v1_chr8_-_47494982_47494982 | 0.16 | 4.3e-03 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr10_-_18574909 Show fit | 37.29 |
ENSRNOT00000083090
|
potassium voltage-gated channel interacting protein 1 |
|
| chr8_+_39305128 Show fit | 37.24 |
ENSRNOT00000008285
|
fasciculation and elongation protein zeta 1 |
|
| chr1_+_27476375 Show fit | 36.80 |
ENSRNOT00000047224
ENSRNOT00000075427 |
sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2-like |
|
| chr11_+_66316606 Show fit | 36.18 |
ENSRNOT00000041715
|
syntaxin binding protein 5-like |
|
| chr11_+_42259761 Show fit | 34.48 |
ENSRNOT00000047310
|
Eph receptor A6 |
|
| chr16_+_78539489 Show fit | 28.42 |
ENSRNOT00000057897
|
CUB and Sushi multiple domains 1 |
|
| chr16_-_39719187 Show fit | 28.19 |
ENSRNOT00000092971
|
glycoprotein m6a |
|
| chr4_-_11610518 Show fit | 27.32 |
ENSRNOT00000066643
|
membrane associated guanylate kinase, WW and PDZ domain containing 2 |
|
| chr11_+_80358211 Show fit | 27.19 |
ENSRNOT00000002519
|
somatostatin |
|
| chr3_-_44086006 Show fit | 22.79 |
ENSRNOT00000034449
ENSRNOT00000082604 |
ermin |
Network of associatons between targets according to the STRING database.
First level regulatory network of Pou2f3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 54.6 | GO:0045760 | positive regulation of action potential(GO:0045760) |
| 0.3 | 42.0 | GO:0007416 | synapse assembly(GO:0007416) |
| 3.1 | 37.2 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.8 | 34.5 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
| 0.4 | 33.9 | GO:0002028 | regulation of sodium ion transport(GO:0002028) |
| 0.6 | 33.0 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
| 0.2 | 30.2 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.7 | 28.4 | GO:0001964 | startle response(GO:0001964) |
| 3.9 | 27.5 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 3.9 | 27.3 | GO:2000809 | positive regulation of synaptic vesicle clustering(GO:2000809) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 57.2 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.5 | 56.6 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.5 | 53.3 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 40.2 | GO:0005874 | microtubule(GO:0005874) |
| 1.5 | 30.6 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.7 | 28.2 | GO:0044295 | axonal growth cone(GO:0044295) |
| 2.7 | 27.3 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 3.8 | 22.8 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.1 | 22.1 | GO:0001726 | ruffle(GO:0001726) |
| 1.0 | 21.9 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 50.2 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.5 | 49.7 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.1 | 40.1 | GO:0005509 | calcium ion binding(GO:0005509) |
| 1.1 | 37.2 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 1.7 | 34.5 | GO:0005003 | ephrin receptor activity(GO:0005003) |
| 6.8 | 27.3 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.1 | 26.0 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.1 | 22.8 | GO:0051015 | actin filament binding(GO:0051015) |
| 4.4 | 21.9 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 0.2 | 21.9 | GO:0051082 | unfolded protein binding(GO:0051082) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 34.5 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 1.3 | 21.0 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.2 | 18.5 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.4 | 17.3 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 1.0 | 15.5 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.7 | 14.1 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 12.4 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 8.7 | PID E2F PATHWAY | E2F transcription factor network |
| 0.3 | 7.4 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.1 | 6.8 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 32.8 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 1.1 | 27.8 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 1.0 | 27.3 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 1.6 | 22.2 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 1.3 | 21.9 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.9 | 21.0 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.7 | 19.9 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 1.2 | 18.6 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 1.3 | 18.1 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.3 | 16.9 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |