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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Pou1f1

Z-value: 2.14

Motif logo

Transcription factors associated with Pou1f1

Gene Symbol Gene ID Gene Info
ENSRNOG00000000715 POU class 1 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou1f1rn6_v1_chr11_+_2645865_2645865-0.487.1e-20Click!

Activity profile of Pou1f1 motif

Sorted Z-values of Pou1f1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_22724399 60.66 ENSRNOT00000002724
UDP glucuronosyltransferase 2 family, polypeptide B10
chr1_-_148119857 56.89 ENSRNOT00000040325
Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chr1_+_147713892 46.49 ENSRNOT00000092985
ENSRNOT00000054742
ENSRNOT00000074103
cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1
chr6_-_127816055 42.70 ENSRNOT00000013175
serine (or cysteine) proteinase inhibitor, clade A, member 3M
chr3_-_63836017 42.12 ENSRNOT00000030978

chr1_-_76722965 41.28 ENSRNOT00000052129
alcohol sulfotransferase-like
chr10_+_53781239 40.07 ENSRNOT00000082871
myosin heavy chain 2
chr1_+_83163079 37.99 ENSRNOT00000077725
ENSRNOT00000034845
cytochrome P450, family 2, subfamily b, polypeptide 3
chr1_-_76614279 37.97 ENSRNOT00000041367
ENSRNOT00000089371
alcohol sulfotransferase-like
chr17_+_32973695 36.31 ENSRNOT00000065674
similar to OTTMUSP00000000621
chr14_+_22806132 35.99 ENSRNOT00000002728
UDP glucuronosyltransferase 2 family, polypeptide B10
chr14_+_22517774 35.91 ENSRNOT00000047655
UDP-glucuronosyltransferase 2 family, member 37
chr2_-_216443518 34.83 ENSRNOT00000022496
amylase, alpha 1A
chr16_+_54153054 33.24 ENSRNOT00000090644
ENSRNOT00000014248
fibrinogen-like 1
chr11_+_7265828 31.62 ENSRNOT00000084765
1,4-alpha-glucan branching enzyme 1
chr4_+_109497962 31.41 ENSRNOT00000057869
regenerating family member 1 alpha
chr4_-_129619142 31.27 ENSRNOT00000047453
leiomodin 3
chr14_-_115052450 29.81 ENSRNOT00000067998
acylphosphatase 2
chr5_-_77408323 29.69 ENSRNOT00000046857
ENSRNOT00000046760
alpha-2u globulin PGCL5
major urinary protein 4
chr1_-_76517134 29.02 ENSRNOT00000064593
ENSRNOT00000085775
alcohol sulfotransferase-like
chr10_+_96639924 28.01 ENSRNOT00000004756
apolipoprotein H
chr14_+_22251499 26.91 ENSRNOT00000087991
ENSRNOT00000002705
UDP glucuronosyltransferase 2 family, polypeptide A1
chr3_-_37803112 26.63 ENSRNOT00000059461
nebulin
chr13_-_56958549 26.06 ENSRNOT00000017293
ENSRNOT00000083912
similar to complement factor H-related protein
chr4_-_41212072 25.77 ENSRNOT00000085596
protein phosphatase 1, regulatory subunit 3A
chr13_-_56693968 24.64 ENSRNOT00000060160

chr4_-_70747226 23.71 ENSRNOT00000044960
anionic trypsin-2-like
chr2_-_216348194 23.47 ENSRNOT00000087839
pancreatic alpha-amylase-like
chr2_-_248484100 23.36 ENSRNOT00000040856
guanylate binding protein 3
chr14_+_22375955 23.21 ENSRNOT00000063915
ENSRNOT00000034784
UDP-glucuronosyltransferase 2 family, member 37
chr5_-_77316764 23.06 ENSRNOT00000071395
ENSRNOT00000076464
major urinary protein 4
chr5_+_90338795 22.85 ENSRNOT00000077864
ENSRNOT00000058882
similar to RIKEN cDNA 2310003M01
chr7_-_138483612 22.65 ENSRNOT00000085620
solute carrier family 38, member 4
chr5_-_77342299 22.59 ENSRNOT00000075994
similar to alpha-2u-globulin
chr7_+_2689501 22.53 ENSRNOT00000041341
apolipoprotein F
chr1_-_258766881 22.41 ENSRNOT00000015801
cytochrome P450, family 2, subfamily c, polypeptide 12
chr1_+_148240504 21.43 ENSRNOT00000085373
Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chr19_+_27404712 21.27 ENSRNOT00000023657
myosin light chain kinase 3
chr4_+_70614524 21.21 ENSRNOT00000041100
protease, serine 3
chr1_+_83744238 21.20 ENSRNOT00000028249
cytochrome P450, family 2, subfamily a, polypeptide 1
chr17_+_33028293 20.46 ENSRNOT00000072764
myosin light chain kinase family, member 4
chr1_-_275882444 20.08 ENSRNOT00000083215
glycerol-3-phosphate acyltransferase, mitochondrial
chr18_+_56193978 19.56 ENSRNOT00000041533
ENSRNOT00000080177
calcium/calmodulin-dependent protein kinase II alpha
chr8_+_52753011 19.44 ENSRNOT00000047264
neurexophilin and PC-esterase domain family, member 1
chr6_+_127946686 19.41 ENSRNOT00000082680
Ab1-233
chr2_-_227207584 19.20 ENSRNOT00000065361
ENSRNOT00000080215
myozenin 2
chrX_-_110232179 19.19 ENSRNOT00000014739
serpin family A member 7
chr1_-_258877045 18.97 ENSRNOT00000071633
cytochrome P450, family 2, subfamily c, polypeptide 13
chr4_-_70628470 18.96 ENSRNOT00000029319
trypsin 5
chr1_+_229030233 18.70 ENSRNOT00000084503
glycine-N-acyltransferase-like 1
chr14_+_26662965 18.67 ENSRNOT00000002621
trans-2,3-enoyl-CoA reductase-like
chr6_-_47890033 18.59 ENSRNOT00000011290
collectin sub-family member 11
chr18_-_15540177 18.47 ENSRNOT00000022113
transthyretin
chr20_+_26999795 18.38 ENSRNOT00000057872
myopalladin
chr5_-_19368431 18.34 ENSRNOT00000012819
cytochrome P450, family 7, subfamily a, polypeptide 1
chr17_+_72160735 18.18 ENSRNOT00000038817
inter-alpha-trypsin inhibitor heavy chain 2
chr2_+_74360622 18.04 ENSRNOT00000014013
cadherin 18
chr1_+_248723397 17.84 ENSRNOT00000072188
mannose-binding protein C-like
chr2_+_88217188 17.77 ENSRNOT00000014267
carbonic anhydrase I
chr4_+_14109864 17.58 ENSRNOT00000076349
similar to fatty acid translocase/CD36
chr6_-_128003418 17.55 ENSRNOT00000013896
serine (or cysteine) proteinase inhibitor, clade A, member 3C
chr6_+_128048099 17.52 ENSRNOT00000084685
ENSRNOT00000087017
Ab1-233
chr2_+_147496229 17.45 ENSRNOT00000022105
transmembrane 4 L six family member 4
chr7_-_14435967 17.24 ENSRNOT00000074801
peptidoglycan recognition protein 2
chr1_+_106896790 17.08 ENSRNOT00000042952
ENSRNOT00000064193
anoctamin 5
chrX_+_110233170 16.76 ENSRNOT00000036019
RIKEN cDNA 4930513O06 gene
chr2_+_227080924 16.72 ENSRNOT00000029871
fatty acid binding protein 2
chr9_-_4327679 16.69 ENSRNOT00000073468
sulfotransferase 1C1-like
chr1_-_76780230 16.66 ENSRNOT00000002046
alcohol sulfotransferase-like
chr20_-_28263037 16.48 ENSRNOT00000030348
ectodysplasin-A receptor
chr4_-_13878126 16.47 ENSRNOT00000007032
G protein subunit alpha transducin 3
chr4_+_70755795 16.38 ENSRNOT00000043527
similar to Anionic trypsin II precursor (Pretrypsinogen II)
chr13_-_56763981 16.23 ENSRNOT00000087916
complement factor H-related protein B
chr15_-_23969011 15.72 ENSRNOT00000014821
GTP cyclohydrolase 1
chr4_+_70689737 15.67 ENSRNOT00000018852
protease, serine, 2
chr6_-_23291568 15.59 ENSRNOT00000085708
CAP-GLY domain containing linker protein family, member 4
chr14_+_22072024 15.57 ENSRNOT00000002680
estrogen sulfotransferase
chr10_+_70262361 15.48 ENSRNOT00000064625
ENSRNOT00000076973
unc-45 myosin chaperone B
chr1_+_137860946 15.39 ENSRNOT00000031334
ATP/GTP binding protein-like 1
chr18_+_35574002 15.38 ENSRNOT00000093442
ENSRNOT00000070817
ENSRNOT00000093356
myotilin
chr3_-_7141522 15.35 ENSRNOT00000014572
carboxyl ester lipase
chr19_-_41686229 15.16 ENSRNOT00000022721
tyrosine aminotransferase
chr5_-_77492013 15.10 ENSRNOT00000012293
alpha-2u globulin PGCL5
chrX_-_13601069 15.07 ENSRNOT00000004686
ornithine carbamoyltransferase
chr14_-_1791636 15.05 ENSRNOT00000072859
vomeronasal 2 receptor, 73
chr9_+_37749059 15.00 ENSRNOT00000071970
myotilin-like
chr1_+_248428099 14.90 ENSRNOT00000050984
mannose binding lectin 2
chr15_-_34550850 14.88 ENSRNOT00000027794
ENSRNOT00000090228
cerebellin 3 precursor
chr4_+_154391647 14.85 ENSRNOT00000081488
ENSRNOT00000079192
murinoglobulin 1
chrM_+_7758 14.85 ENSRNOT00000046201
mitochondrially encoded ATP synthase 8
chr1_-_116919269 14.81 ENSRNOT00000035149

chr1_+_107262659 14.67 ENSRNOT00000022499
growth arrest-specific 2
chr10_+_53713938 14.63 ENSRNOT00000004236
ENSRNOT00000086599
ENSRNOT00000085582
myosin heavy chain 2
chr2_-_173668555 14.60 ENSRNOT00000013452
serpin family I member 2
chr3_+_54253949 14.27 ENSRNOT00000010018
Beta-1,3-galactosyltransferase 1
chr9_-_79530821 14.25 ENSRNOT00000085619
melanoregulin
chr18_-_62476700 14.09 ENSRNOT00000048429
cytochrome c, somatic
chr8_-_111777602 13.97 ENSRNOT00000052317
ENSRNOT00000083855
similar to RIKEN cDNA 1300017J02
chr7_-_29171783 13.96 ENSRNOT00000079235
myosin binding protein C, slow type
chr7_+_38858062 13.90 ENSRNOT00000006234
keratocan
chr1_-_258875572 13.90 ENSRNOT00000093005
cytochrome P450, family 2, subfamily c, polypeptide 13
chr9_+_74124016 13.84 ENSRNOT00000019023
carbamoyl-phosphate synthase 1
chr3_-_74815509 13.82 ENSRNOT00000045173
olfactory receptor 499
chr14_+_22724070 13.79 ENSRNOT00000089471
UDP glucuronosyltransferase 2 family, polypeptide B10
chr8_-_77398156 13.79 ENSRNOT00000091858
ENSRNOT00000085349
ENSRNOT00000082763
lipase C, hepatic type
chr4_+_166833320 13.68 ENSRNOT00000031438
taste receptor, type 2, member 120
chr2_-_211017778 13.66 ENSRNOT00000026883
synaptophysin-like 2
chr17_-_69827112 13.65 ENSRNOT00000023835
aldo-keto reductase family 1, member C14
chr16_+_25773602 13.61 ENSRNOT00000047750
glyceraldehyde-3-phosphate dehydrogenase, pseudogene 2
chr2_+_54466280 13.41 ENSRNOT00000033112
complement C6
chr9_+_119353840 13.37 ENSRNOT00000085362
myomesin 1
chr6_-_138507135 13.31 ENSRNOT00000071078

chr14_-_19132208 13.24 ENSRNOT00000060535
afamin
chr16_+_39909270 13.19 ENSRNOT00000081994
WD repeat domain 17
chr14_-_62595854 13.19 ENSRNOT00000003024
Yip1 domain family, member 7
chr5_+_165465095 13.16 ENSRNOT00000031978
hypothetical protein LOC691354
chr8_+_58431407 13.15 ENSRNOT00000011974
sarcolipin
chr1_+_65576535 13.09 ENSRNOT00000026575
solute carrier family 27 member 5
chr19_+_14835822 12.97 ENSRNOT00000072804
RIKEN cDNA 1700007B14 gene
chr2_+_22950018 12.95 ENSRNOT00000071804
homer scaffolding protein 1
chr15_-_49505553 12.90 ENSRNOT00000028974
ADAM-like, decysin 1
chrM_+_11736 12.84 ENSRNOT00000048767
mitochondrially encoded NADH dehydrogenase 5
chr4_+_154215250 12.68 ENSRNOT00000072465
murinoglobulin 2
chr14_+_84282073 12.57 ENSRNOT00000078271
SEC14-like lipid binding 4
chr13_+_91481461 12.53 ENSRNOT00000012103
olfactory receptor 1576
chr7_-_3805023 12.51 ENSRNOT00000065917
olfactory receptor 881
chr19_+_15294248 12.47 ENSRNOT00000024622
carboxylesterase 1F
chr8_+_52729003 12.42 ENSRNOT00000081738
neurexophilin and PC-esterase domain family, member 4
chr4_-_176231344 12.33 ENSRNOT00000049154
solute carrier organic anion transporter family, member 1a1
chr14_-_1785698 12.29 ENSRNOT00000071182
vomeronasal 2 receptor, 73
chr6_+_128046780 12.19 ENSRNOT00000078064
Ab1-233
chrX_+_51286737 12.16 ENSRNOT00000035692
dystrophin
chr6_-_23316962 12.13 ENSRNOT00000065421
CAP-GLY domain containing linker protein family, member 4
chr11_+_7210209 11.94 ENSRNOT00000076695
1,4-alpha-glucan branching enzyme 1
chr14_-_773281 11.87 ENSRNOT00000045104
ENSRNOT00000050676
ENSRNOT00000049917
vomeronasal 2 receptor, pseudogene 125
chr2_-_19808937 11.86 ENSRNOT00000044237
ATPase H+ transporting accessory protein 1 like
chr4_-_176026133 11.82 ENSRNOT00000043374
ENSRNOT00000046598
solute carrier organic anion transporter family, member 1a4
chr2_+_243502073 11.80 ENSRNOT00000015870
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr8_-_42430928 11.80 ENSRNOT00000072172
olfactory receptor 1257
chr14_+_812382 11.77 ENSRNOT00000041506
ENSRNOT00000039993

chr8_-_38154344 11.72 ENSRNOT00000068043
urinary protein 1-like
chr5_-_22769907 11.72 ENSRNOT00000047805
ENSRNOT00000076167
ENSRNOT00000076507
ENSRNOT00000076113
ENSRNOT00000083779
aspartate-beta-hydroxylase
chr16_-_75518336 11.72 ENSRNOT00000058037
defensin alpha 11
chr16_+_50181316 11.70 ENSRNOT00000077662
coagulation factor XI
chr7_+_11769400 11.63 ENSRNOT00000044417
junctional sarcoplasmic reticulum protein 1
chr4_+_14212925 11.54 ENSRNOT00000076946
platelet glycoprotein 4-like
chr3_-_127500709 11.53 ENSRNOT00000006330
hydroxyacid oxidase 1
chrX_-_104337203 11.52 ENSRNOT00000050903

chr4_+_122244711 11.44 ENSRNOT00000038251
urocanate hydratase 1
chr9_+_8054466 11.40 ENSRNOT00000081513
adhesion G protein-coupled receptor E4
chr3_-_52447622 11.37 ENSRNOT00000083552
sodium voltage-gated channel alpha subunit 1
chr7_+_139685573 11.31 ENSRNOT00000088376
phosphofructokinase, muscle
chr13_-_52834134 11.31 ENSRNOT00000038874
immunoglobulin-like and fibronectin type III domain containing 1
chr4_+_166076156 11.26 ENSRNOT00000007124
proline rich protein 2
chr17_+_15966234 11.16 ENSRNOT00000084304
WNK lysine deficient protein kinase 2
chr2_-_243407608 11.09 ENSRNOT00000014631
microsomal triglyceride transfer protein
chr10_-_46206135 11.08 ENSRNOT00000091471
COP9 signalosome subunit 3
chr4_+_103495993 11.07 ENSRNOT00000072325

chr18_-_64061472 11.01 ENSRNOT00000022519
family with sequence similarity 210, member A
chr3_-_74790822 11.00 ENSRNOT00000045888
olfactory receptor 8K3-like
chr8_+_87211819 11.00 ENSRNOT00000086093
LRRGT00022-like
chr3_+_75936795 10.91 ENSRNOT00000007603
olfactory receptor 588
chr1_+_229722768 10.86 ENSRNOT00000017126
olfactory receptor 339
chr9_+_94286550 10.82 ENSRNOT00000026504
cholinergic receptor nicotinic delta subunit
chr11_+_42259761 10.77 ENSRNOT00000047310
Eph receptor A6
chr9_-_17693200 10.68 ENSRNOT00000026716
mitochondrial ribosomal protein L14
chrX_+_15669191 10.64 ENSRNOT00000013553
MAGI family member, X-linked
chr3_+_69549673 10.53 ENSRNOT00000043974
zinc finger protein 804A
chr9_-_50762082 10.47 ENSRNOT00000015492
methyltransferase like 21C
chr1_+_229889771 10.43 ENSRNOT00000085941
olfactory receptor 348
chr1_+_94718402 10.40 ENSRNOT00000046035
ubiquinol-cytochrome c reductase binding protein
chrX_-_56765893 10.40 ENSRNOT00000076283
interleukin 1 receptor accessory protein-like 1
chr8_-_38549268 10.39 ENSRNOT00000088001
urinary protein 3-like
chr19_-_22194740 10.36 ENSRNOT00000086187
phosphorylase kinase regulatory subunit beta
chr1_+_116869957 10.35 ENSRNOT00000075203
vomeronasal 2 receptor, 25
chr11_-_43617633 10.30 ENSRNOT00000060874
olfactory receptor 1557
chr3_+_112228919 10.23 ENSRNOT00000011761
calpain 3
chr6_-_127656603 10.22 ENSRNOT00000015516
serpin family A member 11
chr2_+_22910236 10.15 ENSRNOT00000078266
homer scaffolding protein 1
chrX_+_145558840 10.14 ENSRNOT00000032522
RIKEN cDNA 4931400O07 gene
chr1_-_49844547 10.14 ENSRNOT00000086127
ENSRNOT00000077423
ENSRNOT00000089439
ENSRNOT00000090521

chr3_+_112228720 10.12 ENSRNOT00000079079
calpain 3
chr3_+_11653529 10.11 ENSRNOT00000091048
adenylate kinase 1
chr11_+_20474483 10.10 ENSRNOT00000082417
ENSRNOT00000002895
neural cell adhesion molecule 2
chr16_-_40025401 10.05 ENSRNOT00000066639
ankyrin repeat and SOCS box-containing 5
chr4_+_101639641 10.03 ENSRNOT00000058282

chr3_-_78016906 10.01 ENSRNOT00000089048
olfactory receptor 687
chrX_-_64726210 9.99 ENSRNOT00000076012
ENSRNOT00000086265
ankyrin repeat and SOCS box-containing 12
chr11_-_81444375 9.87 ENSRNOT00000058479
ENSRNOT00000078131
ENSRNOT00000080949
ENSRNOT00000080562
ENSRNOT00000084867
kininogen 1
chr7_-_70552897 9.87 ENSRNOT00000080594
kinesin family member 5A
chr5_-_77433847 9.86 ENSRNOT00000076906
ENSRNOT00000043056
similar to alpha-2u globulin PGCL2
major urinary protein 4
chrX_-_123867149 9.83 ENSRNOT00000089754
reproductive homeobox on X chromosome 3
chr1_-_173456488 9.83 ENSRNOT00000044753
olfactory receptor 282
chrX_-_65400298 9.79 ENSRNOT00000032121
V-set and immunoglobulin domain containing 4
chr20_-_1109027 9.78 ENSRNOT00000051315
olfactory receptor 1696
chr5_+_132005738 9.77 ENSRNOT00000041421
selection and upkeep of intraepithelial T cells 4
chr4_+_146276862 9.69 ENSRNOT00000009705
solute carrier family 6 member 1
chr1_-_67853552 9.68 ENSRNOT00000080755
ENSRNOT00000003545
vomeronasal 2 receptor, 32
chr16_+_74292438 9.65 ENSRNOT00000026197
voltage-dependent anion channel 3
chr4_+_175814118 9.64 ENSRNOT00000013409
ENSRNOT00000013514
solute carrier organic anion transporter family, member 1B2

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou1f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
10.5 31.4 GO:1990868 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
9.2 248.0 GO:0019373 epoxygenase P450 pathway(GO:0019373)
7.3 58.3 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
7.1 28.3 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
6.8 20.3 GO:1990091 sodium-dependent self proteolysis(GO:1990091)
5.2 15.7 GO:0014916 regulation of lung blood pressure(GO:0014916)
5.0 15.1 GO:0006526 arginine biosynthetic process(GO:0006526)
4.6 13.8 GO:0010034 response to acetate(GO:0010034)
4.5 31.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
4.3 17.2 GO:0002325 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
4.3 21.4 GO:0098953 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
4.3 68.1 GO:0031034 myosin filament assembly(GO:0031034)
4.1 16.3 GO:0002933 lipid hydroxylation(GO:0002933) alkaloid catabolic process(GO:0009822)
4.1 12.2 GO:0016203 muscle attachment(GO:0016203) olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
4.0 19.9 GO:0071400 cellular response to oleic acid(GO:0071400)
3.8 18.9 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
3.6 25.0 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
3.5 14.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
3.4 37.7 GO:0070327 thyroid hormone transport(GO:0070327)
3.4 10.1 GO:0046103 inosine biosynthetic process(GO:0046103)
3.3 13.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
3.3 9.9 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
3.3 13.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
3.1 3.1 GO:1904959 regulation of cytochrome-c oxidase activity(GO:1904959)
3.1 45.8 GO:0034310 primary alcohol catabolic process(GO:0034310)
3.1 9.2 GO:0045959 negative regulation of complement activation, classical pathway(GO:0045959)
2.9 46.0 GO:0035634 response to stilbenoid(GO:0035634)
2.9 11.4 GO:0006548 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
2.8 11.3 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
2.7 16.5 GO:0050917 sensory perception of umami taste(GO:0050917)
2.7 8.1 GO:0021539 subthalamus development(GO:0021539)
2.7 10.7 GO:0001692 histamine metabolic process(GO:0001692)
2.7 8.0 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
2.5 15.2 GO:0006572 tyrosine catabolic process(GO:0006572)
2.4 33.7 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
2.4 7.1 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
2.3 11.7 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
2.3 7.0 GO:0045819 cellular response to water deprivation(GO:0042631) positive regulation of glycogen catabolic process(GO:0045819)
2.3 6.9 GO:0019255 UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255)
2.3 9.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
2.2 20.1 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
2.2 6.7 GO:0009249 protein lipoylation(GO:0009249)
2.2 15.4 GO:0035610 protein side chain deglutamylation(GO:0035610)
2.2 4.3 GO:0031583 phospholipase D-activating G-protein coupled receptor signaling pathway(GO:0031583)
2.2 8.6 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
2.1 8.6 GO:1903413 negative regulation of iron ion transmembrane transport(GO:0034760) cellular response to bile acid(GO:1903413)
2.1 6.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
2.1 14.8 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
2.1 2.1 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
2.1 6.2 GO:0042369 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) vitamin D catabolic process(GO:0042369) response to sodium phosphate(GO:1904383)
2.0 6.1 GO:0043605 cellular amide catabolic process(GO:0043605)
2.0 12.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
2.0 26.1 GO:0052695 cellular glucuronidation(GO:0052695)
2.0 6.0 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) N-acetylneuraminate biosynthetic process(GO:0046380)
2.0 17.6 GO:0061303 cornea development in camera-type eye(GO:0061303)
1.9 5.8 GO:0070946 neutrophil mediated killing of gram-positive bacterium(GO:0070946)
1.9 9.7 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
1.9 5.8 GO:0006552 leucine catabolic process(GO:0006552)
1.9 20.9 GO:0048739 cardiac muscle fiber development(GO:0048739)
1.9 49.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
1.8 27.4 GO:0015671 oxygen transport(GO:0015671)
1.8 5.4 GO:2000359 regulation of binding of sperm to zona pellucida(GO:2000359) negative regulation of binding of sperm to zona pellucida(GO:2000360)
1.8 5.3 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
1.7 2190.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
1.7 3.4 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
1.7 8.3 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
1.7 5.0 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
1.7 26.6 GO:0019236 response to pheromone(GO:0019236)
1.7 1.7 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
1.6 6.6 GO:0009992 cellular water homeostasis(GO:0009992)
1.6 4.9 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
1.6 6.5 GO:0019474 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
1.6 6.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
1.6 8.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.6 9.5 GO:1903352 L-ornithine transmembrane transport(GO:1903352)
1.5 3.1 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
1.5 6.1 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
1.5 9.2 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
1.5 7.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
1.5 6.0 GO:0002434 immune complex clearance(GO:0002434)
1.5 11.8 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
1.4 4.3 GO:0034769 basement membrane disassembly(GO:0034769)
1.4 10.1 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
1.4 5.8 GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
1.4 5.8 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
1.4 5.8 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
1.4 8.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
1.4 5.6 GO:1903576 response to L-arginine(GO:1903576)
1.4 18.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
1.4 5.4 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
1.4 6.8 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
1.3 4.0 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
1.3 4.0 GO:0046687 response to chromate(GO:0046687)
1.3 12.0 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
1.3 21.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
1.3 9.2 GO:0015669 gas transport(GO:0015669)
1.3 10.4 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
1.3 3.8 GO:0033058 directional locomotion(GO:0033058)
1.2 2.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
1.2 6.1 GO:0060327 cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
1.2 4.9 GO:0045423 granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
1.2 27.9 GO:0015721 bile acid and bile salt transport(GO:0015721)
1.2 8.5 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
1.2 2.4 GO:0002314 germinal center B cell differentiation(GO:0002314)
1.1 3.4 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
1.1 13.6 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
1.1 12.4 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
1.1 3.4 GO:0010133 proline catabolic process to glutamate(GO:0010133)
1.1 6.7 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
1.1 3.3 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
1.1 2.2 GO:0014016 neuroblast differentiation(GO:0014016)
1.1 4.4 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
1.0 5.2 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
1.0 3.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
1.0 10.3 GO:0097105 presynaptic membrane assembly(GO:0097105)
1.0 18.5 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
1.0 1.0 GO:0032672 regulation of interleukin-3 production(GO:0032672)
1.0 2.9 GO:0051867 general adaptation syndrome, behavioral process(GO:0051867)
1.0 2.9 GO:0031632 positive regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031632)
0.9 5.7 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.9 13.2 GO:0015693 magnesium ion transport(GO:0015693)
0.9 2.8 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.9 3.7 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.9 2.7 GO:0009644 response to high light intensity(GO:0009644)
0.9 2.7 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.9 2.6 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.9 5.2 GO:0010266 response to vitamin B1(GO:0010266) response to platinum ion(GO:0070541)
0.9 3.4 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.9 5.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.8 16.1 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.8 2.5 GO:0033869 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.8 2.4 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.8 8.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.8 8.0 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.8 8.0 GO:0071373 cellular response to luteinizing hormone stimulus(GO:0071373)
0.8 2.4 GO:0044726 protection of DNA demethylation of female pronucleus(GO:0044726)
0.8 6.3 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.8 8.5 GO:0000338 protein deneddylation(GO:0000338)
0.8 3.9 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.8 13.1 GO:0009750 response to fructose(GO:0009750)
0.8 3.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.8 5.3 GO:0048496 maintenance of organ identity(GO:0048496)
0.8 3.0 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.8 8.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.7 40.3 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.7 2.2 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.7 9.6 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.7 5.9 GO:0030449 regulation of complement activation(GO:0030449)
0.7 5.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.7 2.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.7 3.7 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.7 11.5 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.7 0.7 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.7 8.5 GO:0042407 cristae formation(GO:0042407)
0.7 2.8 GO:0002188 translation reinitiation(GO:0002188)
0.7 8.9 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.7 10.8 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.7 3.4 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.7 11.4 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.7 6.0 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.7 4.0 GO:0070842 aggresome assembly(GO:0070842)
0.6 13.8 GO:0030574 collagen catabolic process(GO:0030574)
0.6 1.9 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.6 32.3 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.6 3.0 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.6 6.0 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.6 1.8 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.6 17.2 GO:0050892 intestinal absorption(GO:0050892)
0.6 1.8 GO:0060764 cell-cell signaling involved in mammary gland development(GO:0060764) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.6 2.9 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.6 9.8 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.6 2.8 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.5 4.9 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.5 3.8 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.5 136.9 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.5 10.3 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.5 2.7 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.5 2.7 GO:0097688 glutamate receptor clustering(GO:0097688)
0.5 4.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.5 2.7 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.5 2.7 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.5 9.4 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.5 2.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.5 3.6 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.5 4.6 GO:0060539 diaphragm development(GO:0060539)
0.5 4.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.5 8.5 GO:0010818 T cell chemotaxis(GO:0010818)
0.5 1.5 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.5 3.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.5 4.7 GO:0045072 regulation of interferon-gamma biosynthetic process(GO:0045072) positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.5 0.5 GO:0071314 cellular response to cocaine(GO:0071314)
0.5 10.6 GO:0045109 intermediate filament organization(GO:0045109)
0.5 1.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.5 7.7 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.5 4.1 GO:0015866 ADP transport(GO:0015866)
0.4 6.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.4 4.4 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.4 11.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.4 4.7 GO:0022904 respiratory electron transport chain(GO:0022904)
0.4 21.2 GO:0050909 sensory perception of taste(GO:0050909)
0.4 4.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.4 0.4 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.4 18.8 GO:0021762 substantia nigra development(GO:0021762)
0.4 1.6 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.4 1.6 GO:0060023 soft palate development(GO:0060023)
0.4 1.6 GO:0097332 response to antipsychotic drug(GO:0097332)
0.4 1.6 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.4 2.3 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.4 4.3 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.4 1.9 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.4 0.8 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.4 5.7 GO:0035641 locomotory exploration behavior(GO:0035641)
0.4 1.1 GO:1901367 response to L-cysteine(GO:1901367)
0.4 1.9 GO:0009624 response to nematode(GO:0009624)
0.4 5.9 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.4 2.2 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.4 5.2 GO:0036315 cellular response to sterol(GO:0036315)
0.4 3.7 GO:1990834 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) response to odorant(GO:1990834)
0.4 0.7 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.4 1.8 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.4 1.1 GO:1901094 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.4 2.5 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.4 2.5 GO:0070054 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
0.4 0.7 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.4 1.4 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.4 1.4 GO:0046222 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.4 10.6 GO:0006073 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.3 1.7 GO:0006311 meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
0.3 6.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.3 1.4 GO:0010157 response to chlorate(GO:0010157)
0.3 1.7 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.3 0.7 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.3 2.0 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.3 25.2 GO:0008203 cholesterol metabolic process(GO:0008203)
0.3 2.3 GO:0003360 brainstem development(GO:0003360)
0.3 3.2 GO:0019321 pentose metabolic process(GO:0019321)
0.3 5.1 GO:0043248 proteasome assembly(GO:0043248)
0.3 1.3 GO:0098963 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.3 3.8 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.3 1.6 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.3 10.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.3 7.8 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.3 5.5 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.3 3.6 GO:0042448 progesterone metabolic process(GO:0042448)
0.3 0.3 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.3 3.9 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.3 1.8 GO:0045792 negative regulation of cell size(GO:0045792)
0.3 3.8 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.3 1.4 GO:0089700 protein kinase D signaling(GO:0089700)
0.3 1.4 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.3 5.1 GO:0007602 phototransduction(GO:0007602)
0.3 3.3 GO:0042711 maternal behavior(GO:0042711)
0.3 1.7 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.3 1.7 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.3 4.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.3 1.4 GO:0060721 regulation of spongiotrophoblast cell proliferation(GO:0060721) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.3 3.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.3 1.9 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
0.3 1.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.3 2.4 GO:0015886 heme transport(GO:0015886)
0.3 1.8 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.3 4.5 GO:0097503 sialylation(GO:0097503)
0.3 3.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.3 1.3 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.3 1.3 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.3 1.8 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.3 2.5 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.2 2.4 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.2 4.3 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.2 1.9 GO:0070417 cellular response to cold(GO:0070417)
0.2 1.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 0.9 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.2 1.1 GO:0019563 glycerol catabolic process(GO:0019563)
0.2 2.0 GO:0030259 lipid glycosylation(GO:0030259)
0.2 2.9 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.2 1.3 GO:0032790 ribosome disassembly(GO:0032790)
0.2 1.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.2 3.8 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.2 2.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.2 0.4 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.2 2.7 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.2 12.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 1.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.2 0.8 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.2 0.6 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.2 7.8 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.2 2.2 GO:0042730 fibrinolysis(GO:0042730)
0.2 2.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 1.1 GO:0015705 iodide transport(GO:0015705)
0.2 1.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.2 2.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.2 0.8 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.2 2.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.2 4.0 GO:0045103 intermediate filament-based process(GO:0045103)
0.2 2.7 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.2 1.6 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.2 1.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.2 0.7 GO:0036371 T-tubule organization(GO:0033292) protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.2 1.4 GO:0061050 regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.2 1.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.2 1.9 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.2 1.0 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 1.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.2 2.0 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.2 2.5 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.2 2.6 GO:0033194 response to hydroperoxide(GO:0033194)
0.2 3.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.2 2.9 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.2 7.0 GO:0051339 regulation of lyase activity(GO:0051339)
0.2 0.3 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.2 1.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 8.7 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.2 2.8 GO:0035584 calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.2 3.0 GO:0048240 sperm capacitation(GO:0048240)
0.2 0.8 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 4.6 GO:0007413 axonal fasciculation(GO:0007413)
0.2 0.8 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.2 1.5 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.2 1.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.6 GO:0033700 phospholipid efflux(GO:0033700)
0.1 3.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 5.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.3 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 1.3 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 4.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 1.1 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 1.8 GO:0042755 eating behavior(GO:0042755)
0.1 0.4 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 2.3 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 1.0 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.8 GO:0032262 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.7 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1 1.4 GO:0007512 adult heart development(GO:0007512)
0.1 2.7 GO:0045116 protein neddylation(GO:0045116)
0.1 1.6 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.8 GO:0050957 equilibrioception(GO:0050957)
0.1 2.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.3 GO:0097327 response to antineoplastic agent(GO:0097327)
0.1 0.3 GO:1903999 regulation of eating behavior(GO:1903998) negative regulation of eating behavior(GO:1903999)
0.1 4.6 GO:0030239 myofibril assembly(GO:0030239)
0.1 1.4 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.1 0.4 GO:0060613 fat pad development(GO:0060613)
0.1 4.1 GO:0032543 mitochondrial translation(GO:0032543)
0.1 5.4 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 1.3 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1 2.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 7.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 0.5 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 1.2 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.8 GO:0019430 removal of superoxide radicals(GO:0019430)
0.1 2.2 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.1 0.5 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.1 0.3 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 1.7 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 1.1 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 0.9 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1 2.0 GO:0009303 rRNA transcription(GO:0009303)
0.1 1.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 1.6 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.4 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 0.9 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.1 0.6 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.1 0.7 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 0.2 GO:0007343 egg activation(GO:0007343)
0.1 0.8 GO:0015677 copper ion import(GO:0015677)
0.1 1.6 GO:0042092 type 2 immune response(GO:0042092)
0.1 2.0 GO:0043039 tRNA aminoacylation for protein translation(GO:0006418) tRNA aminoacylation(GO:0043039)
0.1 0.3 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 1.4 GO:0060479 lung cell differentiation(GO:0060479) lung epithelial cell differentiation(GO:0060487)
0.0 0.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.3 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.6 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.5 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 2.8 GO:0036503 ERAD pathway(GO:0036503)
0.0 0.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.2 GO:0009642 response to light intensity(GO:0009642)
0.0 1.3 GO:0035094 response to nicotine(GO:0035094)
0.0 0.9 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 1.0 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 1.0 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.8 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 2.5 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.1 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.2 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.2 GO:0007339 binding of sperm to zona pellucida(GO:0007339)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 54.7 GO:0005826 actomyosin contractile ring(GO:0005826)
4.9 19.6 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
3.8 11.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
3.1 9.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
2.9 29.5 GO:0045179 apical cortex(GO:0045179)
2.9 14.4 GO:0043159 acrosomal matrix(GO:0043159)
2.6 29.0 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
2.5 27.4 GO:0005833 hemoglobin complex(GO:0005833)
2.3 68.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
2.3 9.2 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
2.2 11.1 GO:0031528 microvillus membrane(GO:0031528)
2.0 8.0 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
1.5 6.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
1.4 4.2 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
1.3 19.8 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
1.3 147.3 GO:0072562 blood microparticle(GO:0072562)
1.3 3.8 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
1.2 63.2 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
1.2 8.4 GO:0061617 MICOS complex(GO:0061617)
1.2 6.0 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.2 14.0 GO:0005859 muscle myosin complex(GO:0005859)
1.1 8.0 GO:0043194 axon initial segment(GO:0043194)
1.1 35.6 GO:0042588 zymogen granule(GO:0042588)
1.1 11.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
1.1 14.7 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
1.0 3.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
1.0 3.1 GO:0034774 secretory granule lumen(GO:0034774)
1.0 9.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.9 4.6 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.9 11.9 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.9 2.7 GO:0098982 glycine-gated chloride channel complex(GO:0016935) GABA-ergic synapse(GO:0098982)
0.9 39.4 GO:0043034 costamere(GO:0043034)
0.9 5.3 GO:0002142 stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696)
0.8 6.8 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.8 9.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.8 0.8 GO:0045275 respiratory chain complex III(GO:0045275)
0.8 4.5 GO:0097441 basilar dendrite(GO:0097441)
0.7 82.8 GO:0030018 Z disc(GO:0030018)
0.7 3.7 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.7 28.3 GO:0031672 A band(GO:0031672)
0.7 2.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.7 19.7 GO:0070469 respiratory chain(GO:0070469)
0.7 13.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.7 7.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.6 3.1 GO:0035061 interchromatin granule(GO:0035061)
0.6 3.1 GO:0072534 perineuronal net(GO:0072534)
0.6 1.2 GO:0005955 calcineurin complex(GO:0005955)
0.6 4.6 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.6 1.7 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.6 2.9 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.6 4.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.6 13.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.6 1.1 GO:0070069 cytochrome complex(GO:0070069)
0.6 1.7 GO:0070939 Dsl1p complex(GO:0070939)
0.5 10.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.5 1.6 GO:0005592 collagen type XI trimer(GO:0005592)
0.5 8.8 GO:0022624 proteasome accessory complex(GO:0022624)
0.5 2.5 GO:0002081 outer acrosomal membrane(GO:0002081)
0.5 1.5 GO:0000802 transverse filament(GO:0000802)
0.5 3.0 GO:0005663 DNA replication factor C complex(GO:0005663)
0.5 12.8 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.5 1.9 GO:0070552 BRISC complex(GO:0070552)
0.5 2.8 GO:0032280 symmetric synapse(GO:0032280)
0.5 8.6 GO:0001520 outer dense fiber(GO:0001520)
0.5 3.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.4 3.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.4 11.6 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.4 4.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.4 25.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.4 22.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.4 8.0 GO:0060170 ciliary membrane(GO:0060170)
0.4 6.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.4 3.9 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.4 1.5 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.4 3.4 GO:0043196 varicosity(GO:0043196)
0.4 61.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.4 1.1 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.4 2.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.4 44.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.3 8.0 GO:0097440 apical dendrite(GO:0097440)
0.3 2.8 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.3 1.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.3 2.1 GO:0051286 cell tip(GO:0051286)
0.3 13.7 GO:0009925 basal plasma membrane(GO:0009925)
0.3 5.7 GO:0097449 astrocyte projection(GO:0097449)
0.3 2.2 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.3 2.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.3 1.6 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.3 7.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3 2.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.3 0.9 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3 2.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.3 5.3 GO:0033270 paranode region of axon(GO:0033270)
0.3 5.0 GO:0033391 chromatoid body(GO:0033391)
0.3 1925.0 GO:0016021 integral component of membrane(GO:0016021)
0.3 0.9 GO:0097433 dense body(GO:0097433)
0.3 1.7 GO:0005921 gap junction(GO:0005921)
0.3 0.8 GO:0045098 type III intermediate filament(GO:0045098)
0.3 1.3 GO:0070695 FHF complex(GO:0070695)
0.3 2.0 GO:0005916 fascia adherens(GO:0005916)
0.2 12.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 0.2 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.2 3.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 26.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.2 249.3 GO:0005615 extracellular space(GO:0005615)
0.2 0.9 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.2 8.6 GO:0030017 sarcomere(GO:0030017)
0.2 1.8 GO:0005869 dynactin complex(GO:0005869)
0.2 2.0 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 5.7 GO:0008180 COP9 signalosome(GO:0008180)
0.2 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 1.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 0.4 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.2 4.9 GO:0005801 cis-Golgi network(GO:0005801)
0.2 3.6 GO:0001673 male germ cell nucleus(GO:0001673)
0.2 2.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 2.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 1.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 2.0 GO:0000801 central element(GO:0000801)
0.2 1.9 GO:0001772 immunological synapse(GO:0001772)
0.2 5.0 GO:0042734 presynaptic membrane(GO:0042734)
0.2 1.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.7 GO:0005675 holo TFIIH complex(GO:0005675)
0.1 0.8 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.9 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 0.7 GO:0070847 core mediator complex(GO:0070847)
0.1 9.4 GO:0031966 mitochondrial membrane(GO:0031966)
0.1 4.1 GO:0016235 aggresome(GO:0016235)
0.1 1.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 2.1 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.4 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 3.4 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.3 GO:1990745 EARP complex(GO:1990745)
0.1 2.0 GO:0043235 receptor complex(GO:0043235)
0.1 0.8 GO:0071564 npBAF complex(GO:0071564)
0.1 0.9 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 0.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.5 GO:0000974 Prp19 complex(GO:0000974)
0.1 1.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 2.7 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 1.7 GO:0000502 proteasome complex(GO:0000502)
0.0 2.7 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 33.9 GO:0005739 mitochondrion(GO:0005739)
0.0 0.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 2.8 GO:0009986 cell surface(GO:0009986)
0.0 0.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0005902 microvillus(GO:0005902)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
19.4 58.3 GO:0004556 alpha-amylase activity(GO:0004556)
17.0 85.2 GO:0005550 pheromone binding(GO:0005550)
14.5 43.6 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
9.3 28.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
8.2 247.3 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
6.4 199.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
5.3 21.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
5.1 15.4 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
5.1 15.2 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
4.6 23.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
4.4 13.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
4.3 17.2 GO:0016019 peptidoglycan receptor activity(GO:0016019)
4.0 15.8 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
3.8 19.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
3.8 19.2 GO:0051373 FATZ binding(GO:0051373)
3.8 22.8 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
3.7 29.8 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
3.4 13.6 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
3.4 10.1 GO:0031721 hemoglobin alpha binding(GO:0031721)
3.3 20.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
3.0 3.0 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
3.0 14.9 GO:0005534 galactose binding(GO:0005534)
3.0 17.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
2.9 41.3 GO:0033038 bitter taste receptor activity(GO:0033038)
2.8 16.7 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
2.4 17.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
2.4 19.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
2.4 11.8 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
2.3 37.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
2.3 7.0 GO:0031893 vasopressin receptor binding(GO:0031893)
2.3 9.2 GO:0019002 GMP binding(GO:0019002)
2.2 15.7 GO:0019238 cyclohydrolase activity(GO:0019238)
2.2 6.7 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
2.2 6.7 GO:0031177 phosphopantetheine binding(GO:0031177)
2.2 8.9 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
2.2 13.1 GO:0015245 fatty acid transporter activity(GO:0015245)
2.2 8.6 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
2.1 6.4 GO:0009384 N-acylmannosamine kinase activity(GO:0009384)
2.1 6.2 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
2.1 831.2 GO:0005549 odorant binding(GO:0005549)
2.0 8.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
2.0 6.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
2.0 13.9 GO:0003996 acyl-CoA ligase activity(GO:0003996)
2.0 27.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
2.0 19.9 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
2.0 7.8 GO:0055100 adiponectin binding(GO:0055100)
1.8 11.0 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
1.8 5.4 GO:0030156 benzodiazepine receptor binding(GO:0030156)
1.7 5.2 GO:0004655 porphobilinogen synthase activity(GO:0004655)
1.7 5.1 GO:0031770 growth hormone-releasing hormone receptor binding(GO:0031770)
1.7 15.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
1.6 11.5 GO:0033592 RNA strand annealing activity(GO:0033592)
1.6 9.9 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
1.6 34.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
1.6 19.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.6 4.9 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
1.6 8.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
1.6 42.9 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.6 18.6 GO:0070324 thyroid hormone binding(GO:0070324)
1.5 4.6 GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding(GO:0071886)
1.5 1350.8 GO:0004984 olfactory receptor activity(GO:0004984)
1.5 5.9 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
1.5 8.9 GO:0005148 prolactin receptor binding(GO:0005148)
1.5 1.5 GO:0032427 GBD domain binding(GO:0032427)
1.5 10.3 GO:0004064 arylesterase activity(GO:0004064)
1.5 5.8 GO:0032190 acrosin binding(GO:0032190)
1.4 17.4 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
1.4 17.4 GO:0005344 oxygen transporter activity(GO:0005344)
1.4 25.9 GO:0005523 tropomyosin binding(GO:0005523)
1.4 16.7 GO:0031432 titin binding(GO:0031432)
1.4 6.9 GO:0032557 pyrimidine ribonucleotide binding(GO:0032557)
1.3 5.4 GO:0050682 AF-2 domain binding(GO:0050682)
1.3 8.0 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
1.3 1.3 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713) alkane 1-monooxygenase activity(GO:0018685)
1.3 5.2 GO:0019166 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
1.3 6.4 GO:0019862 IgA binding(GO:0019862)
1.3 3.8 GO:0047522 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
1.3 6.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
1.3 17.8 GO:0008179 adenylate cyclase binding(GO:0008179)
1.3 3.8 GO:0032810 sterol response element binding(GO:0032810)
1.3 2.5 GO:0004875 complement receptor activity(GO:0004875)
1.3 3.8 GO:0051538 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
1.3 11.3 GO:0070061 fructose binding(GO:0070061)
1.2 6.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
1.2 3.7 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
1.2 8.5 GO:0035375 zymogen binding(GO:0035375)
1.2 4.8 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
1.2 24.9 GO:0034185 apolipoprotein binding(GO:0034185)
1.2 5.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.2 130.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
1.2 5.8 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
1.1 20.4 GO:0001848 complement binding(GO:0001848)
1.1 5.7 GO:0097016 L27 domain binding(GO:0097016)
1.1 3.4 GO:0004657 proline dehydrogenase activity(GO:0004657)
1.1 4.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
1.1 13.4 GO:0004000 adenosine deaminase activity(GO:0004000)
1.1 3.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.0 12.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
1.0 2.9 GO:0000991 transcription factor activity, core RNA polymerase II binding(GO:0000991)
0.9 10.4 GO:0019966 interleukin-1 binding(GO:0019966)
0.9 4.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.9 2.8 GO:0005502 11-cis retinal binding(GO:0005502)
0.9 4.7 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.9 2.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.9 2.7 GO:0022852 glycine-gated chloride ion channel activity(GO:0022852)
0.9 2.7 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.9 4.4 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.9 1.8 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.9 7.0 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.9 3.5 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.9 6.1 GO:0019863 IgE binding(GO:0019863)
0.8 6.8 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.8 2.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.8 16.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.8 8.0 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.8 2.4 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322) oligopeptide transmembrane transporter activity(GO:0035673)
0.8 8.7 GO:0004017 adenylate kinase activity(GO:0004017)
0.8 7.6 GO:0003680 AT DNA binding(GO:0003680)
0.8 0.8 GO:0004985 opioid receptor activity(GO:0004985)
0.8 5.3 GO:0009881 photoreceptor activity(GO:0009881)
0.7 2.2 GO:0047708 biotinidase activity(GO:0047708)
0.7 2.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.7 2.9 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.7 10.8 GO:0042166 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.7 2.9 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829)
0.7 2.9 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.7 5.7 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.7 2.8 GO:0042806 fucose binding(GO:0042806)
0.7 6.0 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.6 4.5 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.6 10.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.6 2.5 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.6 4.9 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.6 9.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.6 16.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.6 7.8 GO:0005243 gap junction channel activity(GO:0005243)
0.6 27.5 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.6 16.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.6 7.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.6 68.1 GO:0005179 hormone activity(GO:0005179)
0.6 11.0 GO:0017166 vinculin binding(GO:0017166)
0.6 4.0 GO:0061133 endopeptidase activator activity(GO:0061133)
0.6 4.6 GO:0008172 S-methyltransferase activity(GO:0008172)
0.6 2.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.6 6.1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.6 5.0 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.5 3.8 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.5 6.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.5 3.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.5 10.8 GO:0005003 ephrin receptor activity(GO:0005003)
0.5 2.7 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.5 2.7 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.5 10.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.5 3.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.5 5.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.5 5.7 GO:0019864 IgG binding(GO:0019864)
0.5 2.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.5 26.0 GO:0009055 electron carrier activity(GO:0009055)
0.5 3.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.5 7.6 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.5 2.0 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.5 3.4 GO:0045499 chemorepellent activity(GO:0045499)
0.5 5.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.5 2.9 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.5 1.9 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.5 1.9 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.5 6.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.5 1.8 GO:0008940 nitrate reductase activity(GO:0008940)
0.5 1.8 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.5 4.1 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.4 4.8 GO:0042301 phosphate ion binding(GO:0042301)
0.4 3.9 GO:0016531 copper chaperone activity(GO:0016531)
0.4 91.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.4 6.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.4 15.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.4 4.9 GO:0016805 dipeptidase activity(GO:0016805)
0.4 4.9 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.4 7.5 GO:0008373 sialyltransferase activity(GO:0008373)
0.4 7.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.4 1.5 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.4 1.9 GO:0004103 choline kinase activity(GO:0004103)
0.4 3.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.4 1.9 GO:0070051 fibrinogen binding(GO:0070051)
0.4 3.4 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.4 1.1 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.4 23.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.4 7.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.4 1.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3 2.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.3 2.0 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.3 2.2 GO:0008430 selenium binding(GO:0008430)
0.3 7.4 GO:0005112 Notch binding(GO:0005112)
0.3 0.9 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.3 3.0 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3 26.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.3 6.7 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.3 1.7 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.3 2.4 GO:0015232 heme transporter activity(GO:0015232)
0.3 5.0 GO:0031402 sodium ion binding(GO:0031402)
0.3 4.2 GO:0016595 glutamate binding(GO:0016595)
0.3 1.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.3 2.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 2.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.2 6.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 6.0 GO:0022829 wide pore channel activity(GO:0022829)
0.2 2.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 3.1 GO:0005542 folic acid binding(GO:0005542)
0.2 6.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 9.9 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.2 10.9 GO:0019842 vitamin binding(GO:0019842)
0.2 0.4 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 0.9 GO:0008312 7S RNA binding(GO:0008312)
0.2 4.1 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.2 1.7 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.2 1.9 GO:0042056 chemoattractant activity(GO:0042056)
0.2 5.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 0.6 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.2 2.9 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.2 12.3 GO:0005080 protein kinase C binding(GO:0005080)
0.2 0.6 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.2 3.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 1.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 4.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 2.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 1.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 0.8 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
0.2 3.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.2 0.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.2 2.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 0.7 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 2.3 GO:0008097 5S rRNA binding(GO:0008097)
0.2 1.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 4.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 1.5 GO:0005167 neurotrophin TRK receptor binding(GO:0005167) neurotrophin TRKA receptor binding(GO:0005168)
0.2 2.5 GO:0008143 poly(A) binding(GO:0008143)
0.2 22.0 GO:0008083 growth factor activity(GO:0008083)
0.2 2.4 GO:0017171 serine hydrolase activity(GO:0017171)
0.2 4.0 GO:0042923 neuropeptide binding(GO:0042923)
0.2 3.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 2.9 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.9 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.1 2.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 3.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 1.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.2 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 4.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.6 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.9 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 1.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 8.5 GO:0020037 heme binding(GO:0020037) tetrapyrrole binding(GO:0046906)
0.1 1.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.4 GO:0004697 protein kinase C activity(GO:0004697)
0.1 9.7 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 1.0 GO:0070402 NADPH binding(GO:0070402)
0.1 0.3 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 41.6 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.1 2.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 2.7 GO:0005109 frizzled binding(GO:0005109)
0.1 1.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.6 GO:0010861 thyroid hormone receptor activator activity(GO:0010861)
0.1 0.9 GO:0016854 racemase and epimerase activity(GO:0016854)
0.1 2.7 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 14.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.8 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 4.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.8 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 1.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 1.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0008265 Mo-molybdopterin cofactor sulfurase activity(GO:0008265) molybdenum ion binding(GO:0030151)
0.0 0.5 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 1.2 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 1.4 GO:0043022 ribosome binding(GO:0043022)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.5 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 10.4 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 31.4 ST JAK STAT PATHWAY Jak-STAT Pathway
2.0 2.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
1.4 2.9 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
1.1 53.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.9 23.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.9 27.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.7 37.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.6 36.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.5 4.2 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.4 106.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.4 5.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.4 1.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.3 24.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.3 8.5 PID CD40 PATHWAY CD40/CD40L signaling
0.2 3.2 PID IL5 PATHWAY IL5-mediated signaling events
0.2 6.0 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.2 3.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.2 8.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.2 4.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.2 4.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.2 2.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.2 3.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.2 2.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 3.4 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.6 PID REELIN PATHWAY Reelin signaling pathway
0.1 3.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 0.4 PID EPO PATHWAY EPO signaling pathway
0.1 2.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 1.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 2.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.6 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.9 PID FGF PATHWAY FGF signaling pathway
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.4 PID IL23 PATHWAY IL23-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
8.0 47.9 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
7.6 143.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
2.4 21.9 REACTOME DEFENSINS Genes involved in Defensins
2.3 34.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
1.7 18.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
1.6 32.9 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
1.5 11.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
1.5 24.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
1.4 24.0 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
1.4 19.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
1.4 52.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
1.3 86.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
1.0 8.1 REACTOME OPSINS Genes involved in Opsins
1.0 12.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.9 2.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.9 10.8 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.8 61.1 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.7 10.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.7 19.2 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.7 6.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.7 11.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.6 12.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.6 15.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.6 18.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.6 103.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.5 2.7 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.5 7.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.5 5.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.5 6.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.5 8.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.5 2.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.4 11.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.4 1.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.4 12.5 REACTOME KINESINS Genes involved in Kinesins
0.4 5.6 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.4 2.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.4 10.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 18.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.3 3.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.3 11.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 16.3 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.3 5.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 3.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.3 11.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.3 5.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 4.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.3 4.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.3 3.9 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.3 1.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 2.7 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.2 4.1 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 2.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 5.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 6.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.2 2.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 3.0 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 7.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 2.0 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.2 2.7 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.2 4.4 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.2 1.5 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.2 3.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 2.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.0 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 1.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 0.8 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 2.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 18.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 16.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 0.9 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 1.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.8 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 1.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 8.2 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 0.8 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 3.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 1.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 1.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.5 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters