Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Plagl1

Z-value: 0.61

Motif logo

logo of

Transcription factors associated with Plagl1

Gene Symbol Gene ID Gene Info
Plagl1
ENSRNOG00000025587 PLAG1 like zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Plagl1rn6_v1_chr1_+_7252349_72523490.283.3e-07Click!

Activity profile of Plagl1 motif

Sorted Z-values of Plagl1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_104095179 23.19 ENSRNOT00000093487
Cldn10
claudin 10
chr12_-_29743705 14.66 ENSRNOT00000001185
Caln1
calneuron 1
chr10_-_31359699 14.13 ENSRNOT00000081280
Cyfip2
cytoplasmic FMR1 interacting protein 2
chr18_-_12640716 12.59 ENSRNOT00000020697
Klhl14
kelch-like family member 14
chr6_-_24985716 11.74 ENSRNOT00000010613
Galnt14
polypeptide N-acetylgalactosaminyltransferase 14
chr10_-_88266210 11.74 ENSRNOT00000090702
ENSRNOT00000020603
Hap1
huntingtin-associated protein 1
chr1_+_219964429 10.79 ENSRNOT00000088288
Sptbn2
spectrin, beta, non-erythrocytic 2
chr8_-_57255263 9.90 ENSRNOT00000028972
LOC100125362
hypothetical protein LOC100125362
chrX_-_11164915 9.34 ENSRNOT00000005138
Atp6ap2
ATPase H+ transporting accessory protein 2
chr5_+_133221139 9.17 ENSRNOT00000047522
Trabd2b
TraB domain containing 2B
chr19_+_56220755 9.09 ENSRNOT00000023452
Tubb3
tubulin, beta 3 class III
chr1_-_82409639 8.68 ENSRNOT00000031326
Erich4
glutamate-rich 4
chr12_-_23661009 8.66 ENSRNOT00000059451
Upk3bl
uroplakin 3B-like
chr12_-_36555694 8.58 ENSRNOT00000001292
Aacs
acetoacetyl-CoA synthetase
chr12_+_22026075 7.59 ENSRNOT00000029041
LOC100910838
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1-like
chr19_+_52086325 7.45 ENSRNOT00000020341
Necab2
N-terminal EF-hand calcium binding protein 2
chr16_+_21050243 6.73 ENSRNOT00000064308
Ncan
neurocan
chr1_-_227175096 6.67 ENSRNOT00000054811
AABR07006259.1

chr4_-_72143748 6.60 ENSRNOT00000024428
Tcaf1
TRPM8 channel-associated factor 1
chr14_-_83062302 6.36 ENSRNOT00000086769
ENSRNOT00000085735
Ywhah
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr3_-_160301552 6.24 ENSRNOT00000014498
Rims4
regulating synaptic membrane exocytosis 4
chr6_+_30038777 6.18 ENSRNOT00000072340
Fam228b
family with sequence similarity 228, member B
chr10_-_55783489 6.05 ENSRNOT00000010415
Alox15b
arachidonate 15-lipoxygenase, type B
chr11_+_47188495 5.92 ENSRNOT00000002188
Nxpe3
neurexophilin and PC-esterase domain family, member 3
chr10_+_59533480 5.86 ENSRNOT00000087723
Atp2a3
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr10_+_59529785 5.75 ENSRNOT00000064840
ENSRNOT00000065181
Atp2a3
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr12_+_23151180 5.71 ENSRNOT00000059486
Cux1
cut-like homeobox 1
chr12_+_23463157 5.63 ENSRNOT00000044841
Cux1
cut-like homeobox 1
chr16_+_80729959 5.58 ENSRNOT00000082049
Tdrp
testis development related protein
chr7_+_144078496 5.49 ENSRNOT00000055302
Pcbp2
poly(rC) binding protein 2
chr2_+_228544418 5.43 ENSRNOT00000013030
Tram1l1
translocation associated membrane protein 1-like 1
chr10_-_66020682 5.36 ENSRNOT00000011019
Fam58b
family with sequence similarity 58, member B
chr10_+_11100917 5.29 ENSRNOT00000006067
Coro7
coronin 7
chr1_-_141451075 5.22 ENSRNOT00000033491
Kif7
kinesin family member 7
chr13_+_90184569 5.19 ENSRNOT00000082393
Slamf1
signaling lymphocytic activation molecule family member 1
chr5_+_154522119 5.19 ENSRNOT00000072618
E2f2
E2F transcription factor 2
chr7_-_12598183 5.11 ENSRNOT00000089009
Arid3a
AT-rich interaction domain 3A
chr1_+_7252349 4.95 ENSRNOT00000030329
Plagl1
PLAG1 like zinc finger 1
chr17_+_9596957 4.95 ENSRNOT00000017349
Fam193b
family with sequence similarity 193, member B
chr1_-_222189604 4.86 ENSRNOT00000028704
Kcnk4
potassium two pore domain channel subfamily K member 4
chr5_-_170679315 4.79 ENSRNOT00000071459
Ajap1
adherens junctions associated protein 1
chr10_-_105368242 4.70 ENSRNOT00000075293
ENSRNOT00000072230
Rnf157
ring finger protein 157
chr7_+_11095468 4.62 ENSRNOT00000061219
Celf5
CUGBP, Elav-like family member 5
chr4_+_57034675 4.53 ENSRNOT00000080223
Smo
smoothened, frizzled class receptor
chr20_+_11114164 4.52 ENSRNOT00000001602
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr20_-_18060661 4.38 ENSRNOT00000070925
AABR07044711.1

chr4_-_144416116 4.28 ENSRNOT00000007724
Oxtr
oxytocin receptor
chr13_-_85443976 4.16 ENSRNOT00000005213
Uck2
uridine-cytidine kinase 2
chrX_-_157312028 4.12 ENSRNOT00000077979
Atp2b3
ATPase plasma membrane Ca2+ transporting 3
chr2_+_165486910 3.97 ENSRNOT00000012982
LOC100362176
hypothetical protein LOC100362176
chr10_-_103816287 3.79 ENSRNOT00000004477
Grin2c
glutamate ionotropic receptor NMDA type subunit 2C
chr8_+_129201669 3.73 ENSRNOT00000025663
Entpd3
ectonucleoside triphosphate diphosphohydrolase 3
chr4_-_145147397 3.63 ENSRNOT00000010347
Lhfpl4
lipoma HMGIC fusion partner-like 4
chr12_-_9990284 3.50 ENSRNOT00000001264
Rasl11a
RAS-like family 11 member A
chr5_+_140870140 3.31 ENSRNOT00000074347
Hpcal4
hippocalcin-like 4
chr1_+_175445088 3.26 ENSRNOT00000036718
Adm
adrenomedullin
chr7_-_144936803 3.12 ENSRNOT00000055279
Gpr84
G protein-coupled receptor 84
chr12_+_49626871 3.06 ENSRNOT00000082593
Grk3
G protein-coupled receptor kinase 3
chr8_+_71514281 3.02 ENSRNOT00000022256
Ns5atp9
NS5A (hepatitis C virus) transactivated protein 9
chr8_+_107882219 3.01 ENSRNOT00000019902
Dzip1l
DAZ interacting zinc finger protein 1-like
chr7_-_12598370 2.98 ENSRNOT00000026708
Arid3a
AT-rich interaction domain 3A
chr4_-_85192834 2.79 ENSRNOT00000043752
Ggct
gamma-glutamyl cyclotransferase
chr13_-_52256196 2.73 ENSRNOT00000011105
Ipo9
importin 9
chr5_+_137546860 2.61 ENSRNOT00000074431
Olr858
olfactory receptor 858
chr1_-_101236065 2.58 ENSRNOT00000066834
Cd37
CD37 molecule
chr10_-_45534570 2.52 ENSRNOT00000058362
Gjc2
gap junction protein, gamma 2
chrX_+_68774699 2.44 ENSRNOT00000081662
Stard8
StAR-related lipid transfer domain containing 8
chr10_-_5253336 2.42 ENSRNOT00000085310
Ciita
class II, major histocompatibility complex, transactivator
chr20_+_6288267 2.40 ENSRNOT00000000627
Srsf3
serine and arginine rich splicing factor 3
chr4_+_121899292 2.37 ENSRNOT00000077949
Vom1r97
vomeronasal 1 receptor 97
chr2_+_120266933 2.37 ENSRNOT00000015192
Ttc14
tetratricopeptide repeat domain 14
chr1_+_170212817 2.34 ENSRNOT00000040672
RGD1561034
similar to hypothetical protein MGC34805
chrX_+_122938009 2.30 ENSRNOT00000089266
ENSRNOT00000017550
Lonrf3
LON peptidase N-terminal domain and ring finger 3
chr3_+_160852164 2.29 ENSRNOT00000019127
Rbpjl
recombination signal binding protein for immunoglobulin kappa J region-like
chr10_+_106785077 2.28 ENSRNOT00000075047
Tmc8
transmembrane channel-like 8
chr9_+_113699170 2.23 ENSRNOT00000017915
Twsg1
twisted gastrulation BMP signaling modulator 1
chr7_-_116920507 2.12 ENSRNOT00000048363
Mroh6
maestro heat-like repeat family member 6
chr7_+_15422479 2.10 ENSRNOT00000066520
Zfp563
zinc finger protein 563
chr1_-_88826302 2.07 ENSRNOT00000028275
Lrfn3
leucine rich repeat and fibronectin type III domain containing 3
chr8_-_132027006 2.03 ENSRNOT00000050963
LOC367195
similar to 60S RIBOSOMAL PROTEIN L7
chr1_-_213987053 1.88 ENSRNOT00000072774
LOC100911519
p53-induced protein with a death domain-like
chr15_+_30550202 1.87 ENSRNOT00000087199
AABR07017745.3

chr15_+_47455690 1.80 ENSRNOT00000075276
LOC100910401
serine protease 55-like
chr8_-_96088364 1.76 ENSRNOT00000086161
ENSRNOT00000056818
Snx14
sorting nexin 14
chr20_+_14578605 1.75 ENSRNOT00000041165
Rtdr1
rhabdoid tumor deletion region gene 1
chr10_+_15108072 1.73 ENSRNOT00000060286
Mslnl
mesothelin-like
chr12_-_21760292 1.71 ENSRNOT00000059592
LOC102550456
TSC22 domain family protein 4-like
chr20_+_11436267 1.69 ENSRNOT00000001631
Trpm2
transient receptor potential cation channel, subfamily M, member 2
chr9_+_92618550 1.68 ENSRNOT00000078987
Sp140
SP140 nuclear body protein
chr16_+_41079444 1.56 ENSRNOT00000015623
Neil3
nei-like DNA glycosylase 3
chr5_+_14415606 1.53 ENSRNOT00000089273
Rgs20
regulator of G-protein signaling 20
chr7_-_12918173 1.35 ENSRNOT00000011010
Tpgs1
tubulin polyglutamylase complex subunit 1
chr15_-_56970365 1.29 ENSRNOT00000047192
Lrch1
leucine rich repeats and calponin homology domain containing 1
chr7_+_130326600 1.26 ENSRNOT00000084776
ENSRNOT00000055808
Ncaph2
non-SMC condensin II complex, subunit H2
chr18_+_29191731 1.22 ENSRNOT00000068085
ENSRNOT00000025495
Cystm1
cysteine-rich transmembrane module containing 1
chr15_-_33766438 1.22 ENSRNOT00000033977
Ap1g2
adaptor-related protein complex 1, gamma 2 subunit
chr13_-_50509916 1.21 ENSRNOT00000076747
Ren
renin
chr15_+_34167945 1.18 ENSRNOT00000032252
Carmil3
capping protein regulator and myosin 1 linker 3
chr2_-_219558675 1.16 ENSRNOT00000020149
Rtcd1
RNA terminal phosphate cyclase domain 1
chr10_-_64862268 1.14 ENSRNOT00000056234
Phf12
PHD finger protein 12
chr1_-_205630073 1.12 ENSRNOT00000037064
Tex36
testis expressed 36
chr7_-_11018160 1.11 ENSRNOT00000092061
Aes
amino-terminal enhancer of split
chr4_+_21862313 1.11 ENSRNOT00000007948
Dmtf1
cyclin D binding myb-like transcription factor 1
chr10_+_86657285 1.08 ENSRNOT00000087346
Thra
thyroid hormone receptor alpha
chr12_+_18996591 1.02 ENSRNOT00000011065
Vamp7
vesicle-associated membrane protein 7
chr13_+_48745860 0.95 ENSRNOT00000010242
Slc45a3
solute carrier family 45, member 3
chr9_-_15306465 0.95 ENSRNOT00000019404
Frs3
fibroblast growth factor receptor substrate 3
chr3_+_103866144 0.94 ENSRNOT00000007688
NEWGENE_1582771
katanin regulatory subunit B1 like 1
chr2_+_252090669 0.92 ENSRNOT00000020656
Lpar3
lysophosphatidic acid receptor 3
chr3_+_172154754 0.86 ENSRNOT00000088286
Stx16
syntaxin 16
chr4_+_78240385 0.86 ENSRNOT00000011041
Zfp775
zinc finger protein 775
chr10_+_47065850 0.74 ENSRNOT00000077868
ENSRNOT00000066250
Dhrs7b
dehydrogenase/reductase 7B
chr9_+_82571269 0.70 ENSRNOT00000026941
Speg
SPEG complex locus
chr15_+_49010492 0.67 ENSRNOT00000024527
Nuggc
nuclear GTPase, germinal center associated
chr1_+_212578450 0.63 ENSRNOT00000064501
Paox
polyamine oxidase
chr15_+_33755478 0.62 ENSRNOT00000034073
Thtpa
thiamine triphosphatase
chr1_+_31700953 0.55 ENSRNOT00000020251
Exoc3
exocyst complex component 3
chr6_-_138068648 0.53 ENSRNOT00000081908
Ighm
immunoglobulin heavy constant mu
chr9_-_9702306 0.46 ENSRNOT00000082341
Trip10
thyroid hormone receptor interactor 10
chr8_-_21523540 0.43 ENSRNOT00000085060
Zfp266
zinc finger protein 266
chr3_-_10694649 0.42 ENSRNOT00000037742
Gpr107
G protein-coupled receptor 107
chr3_+_122285243 0.34 ENSRNOT00000040366
Rpl22l2
ribosomal protein L22-like 2
chr18_+_32594958 0.32 ENSRNOT00000018511
Spry4
sprouty RTK signaling antagonist 4
chr1_+_220806473 0.26 ENSRNOT00000027869
Bles03
basophilic leukemia expressed protein BLES03
chr5_+_14415841 0.26 ENSRNOT00000010682
Rgs20
regulator of G-protein signaling 20
chr13_+_88644520 0.23 ENSRNOT00000003979
Spata46
spermatogenesis associated 46
chr20_+_41083317 0.21 ENSRNOT00000000660
Tspyl1
TSPY-like 1
chr10_+_56187020 0.15 ENSRNOT00000046490
Tp53
tumor protein p53
chr4_-_157230647 0.12 ENSRNOT00000017334
Emg1
EMG1 N1-specific pseudouridine methyltransferase
chr14_-_86796378 0.08 ENSRNOT00000092021
Myo1g
myosin IG
chr4_-_100483168 0.01 ENSRNOT00000019713
Tgoln2
trans-golgi network protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Plagl1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.7 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
2.1 6.4 GO:0006713 glucocorticoid catabolic process(GO:0006713)
2.1 10.5 GO:0002003 angiotensin maturation(GO:0002003)
1.8 14.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.7 5.2 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
1.6 4.9 GO:0071469 cellular response to alkaline pH(GO:0071469)
1.3 3.8 GO:0033058 directional locomotion(GO:0033058)
1.2 6.1 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
1.1 4.5 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
1.0 4.2 GO:0044211 CTP salvage(GO:0044211)
1.0 3.1 GO:0042441 eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) rhodopsin metabolic process(GO:0046154)
0.9 6.6 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.9 9.2 GO:0018158 protein oxidation(GO:0018158)
0.9 10.8 GO:0016081 synaptic vesicle docking(GO:0016081)
0.9 5.2 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.9 8.6 GO:0034201 response to oleic acid(GO:0034201)
0.9 4.3 GO:0034059 positive regulation of norepinephrine secretion(GO:0010701) response to anoxia(GO:0034059)
0.6 2.6 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.6 5.5 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.5 11.3 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.5 4.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.4 6.7 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.4 5.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.4 1.7 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.4 3.7 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.4 2.2 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.4 1.1 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.3 2.4 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.3 1.0 GO:1903778 positive regulation of histamine secretion by mast cell(GO:1903595) protein localization to vacuolar membrane(GO:1903778)
0.3 3.3 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.3 0.9 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.3 5.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.3 1.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 0.6 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.2 1.7 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 6.2 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.2 5.2 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 3.5 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 1.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 2.3 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
0.1 2.1 GO:0019236 response to pheromone(GO:0019236)
0.1 0.6 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 1.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.7 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.9 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 1.8 GO:0097352 autophagosome maturation(GO:0097352)
0.1 5.0 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 0.7 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 11.7 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 2.9 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.0 7.4 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.6 GO:0051601 exocyst localization(GO:0051601)
0.0 0.5 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0 4.0 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 1.6 GO:0006284 base-excision repair(GO:0006284)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 2.4 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.1 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 4.0 GO:0007411 axon guidance(GO:0007411)
0.0 0.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.9 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 6.9 GO:0048812 neuron projection morphogenesis(GO:0048812)
0.0 8.7 GO:0016567 protein ubiquitination(GO:0016567)
0.0 0.7 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 4.9 GO:0007283 spermatogenesis(GO:0007283)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 10.8 GO:0008091 spectrin(GO:0008091)
0.5 14.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.4 4.5 GO:0044294 dendritic growth cone(GO:0044294)
0.3 1.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.3 3.1 GO:0044292 dendrite terminus(GO:0044292)
0.3 11.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.3 12.6 GO:0016235 aggresome(GO:0016235)
0.2 11.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 11.7 GO:1904115 axon cytoplasm(GO:1904115)
0.2 3.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 23.2 GO:0005923 bicellular tight junction(GO:0005923)
0.2 1.3 GO:0000796 condensin complex(GO:0000796)
0.1 2.5 GO:0005922 connexon complex(GO:0005922)
0.1 6.2 GO:0048786 presynaptic active zone(GO:0048786)
0.1 5.2 GO:0005871 kinesin complex(GO:0005871)
0.1 1.1 GO:0016580 Sin3 complex(GO:0016580)
0.1 2.6 GO:0001772 immunological synapse(GO:0001772)
0.1 1.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 3.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 8.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 4.9 GO:0034705 potassium channel complex(GO:0034705)
0.0 4.4 GO:0005902 microvillus(GO:0005902)
0.0 9.2 GO:0031301 integral component of organelle membrane(GO:0031301)
0.0 2.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 3.0 GO:0005814 centriole(GO:0005814)
0.0 0.6 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 9.9 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 7.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 9.8 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 9.0 GO:0005874 microtubule(GO:0005874)
0.0 4.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.6 GO:0016605 PML body(GO:0016605)
0.0 6.1 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 1.7 GO:0043204 perikaryon(GO:0043204)
0.0 1.8 GO:0005770 late endosome(GO:0005770)
0.0 0.4 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 9.1 GO:0045202 synapse(GO:0045202)
0.0 3.7 GO:0005925 focal adhesion(GO:0005925)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.7 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
1.6 4.9 GO:0097603 temperature-gated ion channel activity(GO:0097603)
1.1 5.5 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
1.0 8.6 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.8 4.2 GO:0004849 uridine kinase activity(GO:0004849)
0.7 15.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.7 2.8 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.5 3.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.5 4.5 GO:0005113 patched binding(GO:0005113)
0.4 3.1 GO:0004966 galanin receptor activity(GO:0004966)
0.4 4.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.4 3.8 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.3 5.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3 0.9 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.3 4.5 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.3 1.4 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.3 11.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 6.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 2.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 6.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.2 3.7 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.2 0.9 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 1.6 GO:0000405 bubble DNA binding(GO:0000405)
0.2 1.7 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.2 0.6 GO:0046592 polyamine oxidase activity(GO:0046592)
0.2 19.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 2.5 GO:0005243 gap junction channel activity(GO:0005243)
0.1 3.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 1.2 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.1 6.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 3.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 2.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 2.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 1.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 12.8 GO:0044325 ion channel binding(GO:0044325)
0.1 1.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 1.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 1.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 5.2 GO:0001047 core promoter binding(GO:0001047)
0.0 11.7 GO:0016757 transferase activity, transferring glycosyl groups(GO:0016757)
0.0 23.1 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 2.3 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 3.3 GO:0005179 hormone activity(GO:0005179)
0.0 2.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 7.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 8.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.3 5.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3 14.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 6.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 6.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 4.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.8 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 3.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 4.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.9 PID SHP2 PATHWAY SHP2 signaling
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.9 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 23.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.6 15.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.5 9.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.5 6.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.4 11.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.4 4.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 10.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 5.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.2 11.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.2 3.8 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.2 4.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.2 5.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 4.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 2.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 2.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 7.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.4 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 1.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 2.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.9 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 5.2 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.9 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 2.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors