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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Pax7

Z-value: 0.48

Motif logo

Transcription factors associated with Pax7

Gene Symbol Gene ID Gene Info
ENSRNOG00000018739 paired box 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pax7rn6_v1_chr5_-_158313426_158313426-0.203.5e-04Click!

Activity profile of Pax7 motif

Sorted Z-values of Pax7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_5709236 18.28 ENSRNOT00000061201
ENSRNOT00000070887
dopamine beta-hydroxylase
chr17_+_43423111 18.24 ENSRNOT00000022630
histone cluster 1 H2B family member a
chr10_-_103826448 16.85 ENSRNOT00000085636
ferredoxin reductase
chr1_-_227457629 14.61 ENSRNOT00000035910
ENSRNOT00000073770
membrane spanning 4-domains A5
chr9_+_53013413 14.35 ENSRNOT00000005313
ankyrin and armadillo repeat containing
chr7_-_28711761 8.65 ENSRNOT00000006249
PARP1 binding protein
chr3_+_70327193 7.94 ENSRNOT00000089165
fibrous sheath-interacting protein 2
chr1_+_201337416 7.15 ENSRNOT00000067742
BTB domain containing 16
chr2_+_104020955 6.95 ENSRNOT00000045586
mitochondrial fission regulator 1
chr10_-_74679858 6.81 ENSRNOT00000003859
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr5_+_28485619 6.50 ENSRNOT00000093341
ENSRNOT00000093129
uncharacterized LOC100912373
chr8_-_6305033 6.22 ENSRNOT00000029887
centrosomal protein 126
chr11_-_61234944 6.00 ENSRNOT00000059680
cilia and flagella associated protein 44
chr18_+_45023932 5.98 ENSRNOT00000039379
family with sequence similarity 170, member A
chr14_+_23405717 5.80 ENSRNOT00000029805
transmembrane protease, serine 11C
chr11_-_43022565 5.62 ENSRNOT00000002285
ribosomal oxygenase 2
chr20_+_32717564 5.46 ENSRNOT00000030642
regulatory factor X, 6
chr16_+_9023387 5.07 ENSRNOT00000067761
similar to novel protein
chr18_-_13183263 4.95 ENSRNOT00000050933
coiled-coil domain containing 178
chr2_+_202200797 4.87 ENSRNOT00000042263
ENSRNOT00000071938
sperm associated antigen 17
chr1_+_128637049 4.83 ENSRNOT00000018639
tetratricopeptide repeat domain 23
chr3_-_8659102 4.80 ENSRNOT00000050908
zinc finger, DHHC-type containing 12
chrX_+_14019961 4.72 ENSRNOT00000004785
synaptotagmin-like 5
chr7_+_78558701 4.54 ENSRNOT00000006393
regulating synaptic membrane exocytosis 2
chr4_-_183424449 4.49 ENSRNOT00000071930
family with sequence similarity 60, member A
chr6_+_76349362 4.47 ENSRNOT00000043224
aldolase 1 A retrogene 2
chr18_+_79773608 4.39 ENSRNOT00000088484
zinc finger protein 516
chr4_-_80395502 4.32 ENSRNOT00000014437
neuropeptide VF precursor
chr10_-_65502936 4.29 ENSRNOT00000089615
SPT6 homolog, histone chaperone
chr1_+_101603222 4.25 ENSRNOT00000033278
izumo sperm-egg fusion 1
chr1_+_15834779 4.15 ENSRNOT00000079069
ENSRNOT00000083012
BCL2-associated transcription factor 1
chr6_-_108660063 4.13 ENSRNOT00000006240
apoptosis resistant E3 ubiquitin protein ligase 1
chr3_-_165700489 3.82 ENSRNOT00000017008
zinc finger protein 93
chr9_+_8052210 3.77 ENSRNOT00000073659
adhesion G protein-coupled receptor E4
chr2_-_33025271 3.62 ENSRNOT00000074941
microtubule associated serine/threonine kinase family member 4
chr1_+_224998172 3.61 ENSRNOT00000026321
zinc finger and BTB domain containing 3
chr15_+_31950986 3.57 ENSRNOT00000080233

chr9_+_60039297 3.48 ENSRNOT00000016262
solute carrier family 39 member 10
chr13_-_76049363 3.44 ENSRNOT00000075865
ENSRNOT00000007455
BMP/retinoic acid inducible neural specific 2
chr16_-_29936307 3.35 ENSRNOT00000088707
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr9_+_71915421 3.34 ENSRNOT00000020447
phosphoinositide kinase, FYVE-type zinc finger containing
chrX_+_131381134 3.31 ENSRNOT00000007474

chr2_+_80269661 3.22 ENSRNOT00000015975

chr1_-_261179790 3.15 ENSRNOT00000074420
ENSRNOT00000072073
exosome component 1
chr17_-_30661690 3.09 ENSRNOT00000048146
similar to RIKEN cDNA 4933417A18
chr3_+_75906945 3.05 ENSRNOT00000047110
olfactory receptor 586
chr8_+_104106740 2.94 ENSRNOT00000015015
transcription factor Dp-2
chr9_-_78607307 2.71 ENSRNOT00000057672
ATP binding cassette subfamily A member 12
chr18_+_28594892 2.60 ENSRNOT00000067702
ubiquitin-conjugating enzyme E2D 2
chrX_+_105147534 2.56 ENSRNOT00000046288
centromere protein I
chr2_+_66940057 2.54 ENSRNOT00000043050
cadherin 9
chr1_+_101554642 2.54 ENSRNOT00000028474
branched chain amino acid transaminase 2
chr3_-_90751055 2.49 ENSRNOT00000040741
LRRGT00091
chr7_+_2459141 2.27 ENSRNOT00000075681
nascent polypeptide-associated complex alpha subunit
chrX_+_105147153 2.10 ENSRNOT00000088172
centromere protein I
chr4_+_147832136 2.01 ENSRNOT00000064603
rhodopsin
chr2_+_198417619 1.99 ENSRNOT00000085945
histone cluster 2, H3c2
chr2_-_122646445 1.97 ENSRNOT00000080100
defective in cullin neddylation 1 domain containing 1
chr5_-_162751128 1.97 ENSRNOT00000068281
similar to novel protein similar to esterases
chr7_-_69982592 1.82 ENSRNOT00000040010
similar to developmental pluripotency associated 5
chr3_+_3389612 1.74 ENSRNOT00000041984
ribosomal protein L8
chr10_+_29289203 1.61 ENSRNOT00000067013
PWWP domain containing 2A
chr7_-_64887448 1.50 ENSRNOT00000038147
DNA helicase B
chr12_-_45801842 1.49 ENSRNOT00000078837

chr2_-_170301348 1.48 ENSRNOT00000088131
sucrase-isomaltase
chr7_-_121000272 1.43 ENSRNOT00000020941
dynein, axonemal, light chain 4
chr10_-_57837602 1.41 ENSRNOT00000075185
NLR family, pyrin domain containing 1B
chr3_+_138398011 1.41 ENSRNOT00000038865
mitochondrial genome maintenance exonuclease 1
chr7_+_2752680 1.40 ENSRNOT00000033726
citrate synthase
chr3_+_73327828 1.31 ENSRNOT00000071299
similar to olfactory receptor Olr470
chr10_-_88670430 1.28 ENSRNOT00000025547
hypocretin neuropeptide precursor
chrX_-_40086870 1.08 ENSRNOT00000010027
small muscle protein, X-linked
chr17_-_78735324 0.93 ENSRNOT00000036299
cerebral dopamine neurotrophic factor
chr16_+_48513432 0.84 ENSRNOT00000044934
similar to NADH-ubiquinone oxidoreductase B9 subunit (Complex I-B9) (CI-B9)
chr4_+_156253079 0.75 ENSRNOT00000013536
C-type lectin domain family 4, member D
chr4_+_82637411 0.68 ENSRNOT00000048225
LRRGT00062
chr6_+_145546595 0.65 ENSRNOT00000007112
Rap guanine nucleotide exchange factor 5
chr8_+_43781921 0.63 ENSRNOT00000078003
olfactory receptor 1329
chr18_-_15688284 0.61 ENSRNOT00000091816
desmoglein 3
chr2_-_58534211 0.59 ENSRNOT00000089178
S-phase kinase associated protein 2
chrM_+_7006 0.56 ENSRNOT00000043693
mitochondrially encoded cytochrome c oxidase II
chr10_-_67401836 0.51 ENSRNOT00000073071
cytokine receptor-like factor 3
chr2_+_127525285 0.51 ENSRNOT00000093247
inturned planar cell polarity protein
chr4_-_165832323 0.48 ENSRNOT00000007497
taste receptor, type 2, member 114
chr10_-_87521514 0.43 ENSRNOT00000084668
ENSRNOT00000071705
keratin associated protein 2-4-like
chr10_+_61640015 0.41 ENSRNOT00000092714
methyltransferase like 16
chr8_+_5790034 0.39 ENSRNOT00000061887
matrix metallopeptidase 27
chr14_-_16903242 0.28 ENSRNOT00000003001
shroom family member 3
chr3_+_73366155 0.28 ENSRNOT00000044979
olfactory receptor 473
chr17_+_78735598 0.28 ENSRNOT00000020854
heat shock protein family A, member 14
chr12_+_47590154 0.23 ENSRNOT00000045946
GIT ArfGAP 2
chr9_+_23596964 0.23 ENSRNOT00000064279
exocrine gland-secreted peptide 1-like
chr4_-_88684415 0.05 ENSRNOT00000009001
similar to 40S ribosomal protein S7 (S8)

Network of associatons between targets according to the STRING database.

First level regulatory network of Pax7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 18.3 GO:0046333 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
3.0 18.2 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
1.7 16.9 GO:0070995 NADPH oxidation(GO:0070995)
1.2 4.9 GO:1904158 axonemal central apparatus assembly(GO:1904158)
1.0 10.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.8 2.5 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.8 2.3 GO:1901227 negative regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901227)
0.7 4.3 GO:0070827 chromatin maintenance(GO:0070827)
0.6 5.6 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.5 5.5 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.5 2.7 GO:0035627 ceramide transport(GO:0035627)
0.5 5.8 GO:0097264 self proteolysis(GO:0097264)
0.5 4.7 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.5 6.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.4 4.3 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.4 3.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.3 4.5 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.3 4.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.3 6.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.3 6.0 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.2 2.0 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 1.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 8.3 GO:0009060 aerobic respiration(GO:0009060)
0.1 3.3 GO:0032288 myelin assembly(GO:0032288)
0.1 1.4 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 4.2 GO:0018345 protein palmitoylation(GO:0018345)
0.1 4.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 5.6 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 2.0 GO:0045116 protein neddylation(GO:0045116)
0.1 4.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.6 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 1.5 GO:0009750 response to fructose(GO:0009750)
0.1 2.0 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 4.5 GO:0006096 glycolytic process(GO:0006096)
0.1 1.4 GO:0050718 positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0 2.6 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 3.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 4.2 GO:2001022 positive regulation of response to DNA damage stimulus(GO:2001022)
0.0 0.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 2.5 GO:0006334 nucleosome assembly(GO:0006334)
0.0 4.1 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 1.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.9 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 3.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.5 GO:1904894 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0 0.7 GO:0002292 T cell differentiation involved in immune response(GO:0002292)
0.0 0.5 GO:0050912 detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.0 0.6 GO:0009409 response to cold(GO:0009409)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 18.3 GO:0034774 secretory granule lumen(GO:0034774)
1.0 4.9 GO:1990716 axonemal central apparatus(GO:1990716)
0.5 2.7 GO:0097209 epidermal lamellar body(GO:0097209)
0.3 4.5 GO:0016580 Sin3 complex(GO:0016580)
0.3 3.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.3 3.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 4.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 1.1 GO:0005927 muscle tendon junction(GO:0005927)
0.2 20.2 GO:0000786 nucleosome(GO:0000786)
0.2 1.4 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.2 6.2 GO:0097546 ciliary base(GO:0097546)
0.2 1.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 4.2 GO:0002080 acrosomal membrane(GO:0002080)
0.1 2.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 2.7 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 18.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 12.3 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 4.7 GO:0000776 kinetochore(GO:0000776)
0.0 1.4 GO:0030286 dynein complex(GO:0030286)
0.0 8.3 GO:0000785 chromatin(GO:0000785)
0.0 8.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 4.7 GO:0070382 exocytic vesicle(GO:0070382)
0.0 1.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 12.3 GO:0005730 nucleolus(GO:0005730)
0.0 2.6 GO:0043204 perikaryon(GO:0043204)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 18.3 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
1.4 4.3 GO:0000991 transcription factor activity, core RNA polymerase II binding(GO:0000991)
1.1 5.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.9 16.9 GO:0070402 NADPH binding(GO:0070402)
0.8 2.5 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.6 4.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.5 6.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.5 1.5 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.5 4.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.5 2.7 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.4 3.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.3 1.7 GO:1990932 5.8S rRNA binding(GO:1990932)
0.3 1.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 1.5 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2 2.0 GO:0009881 photoreceptor activity(GO:0009881)
0.2 1.4 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1 4.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 3.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.0 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.4 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1 3.2 GO:0004532 exoribonuclease activity(GO:0004532)
0.1 2.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 4.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 2.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 4.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 24.8 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 5.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0008527 taste receptor activity(GO:0008527)
0.0 5.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 18.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.3 16.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 2.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 3.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 2.9 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 16.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.7 18.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.3 3.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.3 2.0 REACTOME OPSINS Genes involved in Opsins
0.2 1.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 3.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2 4.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 3.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 2.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 2.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase