Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Pax5

Z-value: 1.36

Motif logo

Transcription factors associated with Pax5

Gene Symbol Gene ID Gene Info
ENSRNOG00000024729 paired box 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pax5rn6_v1_chr5_-_60191941_601919410.339.9e-10Click!

Activity profile of Pax5 motif

Sorted Z-values of Pax5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_119441487 54.85 ENSRNOT00000067635
parvalbumin
chr10_-_56167426 41.77 ENSRNOT00000013955
ephrin B3
chr10_+_65586993 32.73 ENSRNOT00000086036
aldolase, fructose-bisphosphate C
chr10_-_15928169 32.21 ENSRNOT00000028069
neuron specific gene family member 2
chr13_-_90676629 28.98 ENSRNOT00000058143
ATPase Na+/K+ transporting subunit alpha 2
chr1_-_93949187 28.66 ENSRNOT00000018956
zinc finger protein 536
chr3_-_72602548 28.36 ENSRNOT00000031745
leucine rich repeat containing 55
chr5_+_147323240 28.31 ENSRNOT00000047152
fibronectin type III domain containing 5
chr20_-_4823475 26.95 ENSRNOT00000082536
ENSRNOT00000001114
ATPase H+ transporting V1 subunit G2
chr8_-_98738446 26.25 ENSRNOT00000019860
Zic family member 1
chr16_-_18974729 24.32 ENSRNOT00000086424
ENSRNOT00000064060
transmembrane protein 38a
chr1_-_265560386 24.13 ENSRNOT00000048592
Kv channel-interacting protein 2-like
chr1_+_262905570 23.95 ENSRNOT00000090765
potassium voltage-gated channel interacting protein 2
chr11_-_83905889 22.87 ENSRNOT00000075606
family with sequence similarity 131, member A
chr11_-_82884660 22.84 ENSRNOT00000073526
protein FAM131A-like
chr2_+_210977938 22.43 ENSRNOT00000074725
adhesion molecule with Ig like domain 1
chr15_-_33775109 22.13 ENSRNOT00000033722
junctophilin 4
chr8_+_39305128 21.43 ENSRNOT00000008285
fasciculation and elongation protein zeta 1
chr15_+_33600102 21.06 ENSRNOT00000022664
CKLF-like MARVEL transmembrane domain containing 5
chr14_-_55081551 20.86 ENSRNOT00000049245
protocadherin 7
chr8_+_29453643 20.76 ENSRNOT00000090643
opioid binding protein/cell adhesion molecule-like
chr2_+_220298245 20.72 ENSRNOT00000022625
phospholipid phosphatase related 4
chrX_+_70563570 20.43 ENSRNOT00000003772
glycerophosphodiester phosphodiesterase domain containing 2
chr10_-_90999506 20.38 ENSRNOT00000034401
glial fibrillary acidic protein
chr5_-_144779212 20.37 ENSRNOT00000016230
neurochondrin
chr4_-_169999873 19.93 ENSRNOT00000011697
glutamate ionotropic receptor NMDA type subunit 2B
chr11_+_80358211 19.91 ENSRNOT00000002519
somatostatin
chr9_-_21338582 18.77 ENSRNOT00000016940
patched domain containing 4
chr10_+_65586504 18.76 ENSRNOT00000015535
ENSRNOT00000046388
aldolase, fructose-bisphosphate C
chr15_+_33600337 18.65 ENSRNOT00000075965
CKLF-like MARVEL transmembrane domain containing 5
chr9_-_85243001 18.63 ENSRNOT00000020219
secretogranin II
chr2_+_188844073 18.60 ENSRNOT00000028117
potassium calcium-activated channel subfamily N member 3
chr6_-_137084739 18.42 ENSRNOT00000060943
transmembrane protein 179
chrX_+_105239840 18.11 ENSRNOT00000039864
dystrophin related protein 2
chr10_-_74679858 18.02 ENSRNOT00000003859
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr13_-_49313940 17.93 ENSRNOT00000012190
contactin 2
chrX_-_157028434 17.93 ENSRNOT00000080088
plexin B3
chr4_+_110700403 17.88 ENSRNOT00000092379
leucine rich repeat transmembrane neuronal 4
chrX_-_15707436 17.54 ENSRNOT00000085907
synaptophysin
chr17_-_10818835 17.51 ENSRNOT00000091046
complexin 2
chr1_-_5165859 17.04 ENSRNOT00000044325
ENSRNOT00000019319
glutamate metabotropic receptor 1
chr20_+_7279820 16.50 ENSRNOT00000090820
protein kinase C and casein kinase substrate in neurons 1
chr2_+_41157823 16.43 ENSRNOT00000066384
phosphodiesterase 4D
chr4_-_157381105 16.42 ENSRNOT00000021670
G protein-coupled receptor 162
chr14_+_2194933 16.42 ENSRNOT00000061720
complexin 1
chr6_+_41917132 16.16 ENSRNOT00000071387
neurotensin receptor 2
chr14_+_37116492 16.14 ENSRNOT00000002921
sarcoglycan, beta
chr4_-_52350624 15.96 ENSRNOT00000060476
transmembrane protein 229A
chr8_+_118333706 15.70 ENSRNOT00000028278
chondroitin sulfate proteoglycan 5
chr3_+_47995959 15.40 ENSRNOT00000082775
solute carrier family 4 member 10
chrX_+_23081125 15.27 ENSRNOT00000071639

chr7_+_141346398 15.18 ENSRNOT00000077175
acid sensing ion channel subunit 1
chr7_-_121029754 14.99 ENSRNOT00000004703
neuronal pentraxin receptor
chr4_+_35279063 14.91 ENSRNOT00000011833
neurexophilin 1
chr4_-_157078130 14.86 ENSRNOT00000015570
calsyntenin 3
chr16_-_64806050 14.53 ENSRNOT00000015725
dual specificity phosphatase 26
chr14_+_115275894 14.38 ENSRNOT00000033437
G protein-coupled receptor 75
chr11_+_75905443 14.33 ENSRNOT00000002650
fibroblast growth factor 12
chr6_-_142585188 14.10 ENSRNOT00000067437

chr13_-_111581018 14.09 ENSRNOT00000083072
ENSRNOT00000077981
SERTA domain containing 4
chr7_+_145117951 14.03 ENSRNOT00000055272
phosphodiesterase 1B
chr12_-_5773036 13.99 ENSRNOT00000041365
FRY microtubule binding protein
chr18_-_73873280 13.82 ENSRNOT00000075580
ring finger protein 165
chr1_+_199449973 13.61 ENSRNOT00000029994
tripartite motif containing 72
chr3_+_11629556 13.60 ENSRNOT00000074401
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr10_+_89089646 13.52 ENSRNOT00000027505
contactin associated protein 1
chr6_+_110624856 13.42 ENSRNOT00000014017
vasohibin 1
chr14_+_25589762 13.41 ENSRNOT00000043938
ENSRNOT00000067439
ENSRNOT00000002793
EPH receptor A5
chr13_+_89622632 13.09 ENSRNOT00000004713
ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr7_+_70364813 12.93 ENSRNOT00000084012
ENSRNOT00000031230
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr15_-_44860604 12.73 ENSRNOT00000018637
neurofilament medium
chr4_+_64088900 12.62 ENSRNOT00000075341
cholinergic receptor, muscarinic 2
chr15_-_95514259 12.62 ENSRNOT00000038433
SLIT and NTRK-like family, member 6
chr19_+_55669626 12.22 ENSRNOT00000033352
cadherin 15
chr13_-_49487892 12.10 ENSRNOT00000044972
neurofascin
chr8_+_27777179 11.88 ENSRNOT00000009825
beta-1,3-glucuronyltransferase 1
chr12_+_39554171 11.77 ENSRNOT00000024347
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
chr1_+_97632473 11.62 ENSRNOT00000023671
V-set and transmembrane domain containing 2B
chr6_-_141488290 11.56 ENSRNOT00000067336

chr11_+_66713888 11.40 ENSRNOT00000003340
F-box protein 40
chr13_-_51992693 11.37 ENSRNOT00000008282
G protein-coupled receptor 37-like 1
chr7_-_98709344 11.29 ENSRNOT00000064122
transmembrane protein 65
chr3_-_160301552 11.28 ENSRNOT00000014498
regulating synaptic membrane exocytosis 4
chr14_+_8182383 10.87 ENSRNOT00000092719
mitogen activated protein kinase 10
chr1_-_170404056 10.84 ENSRNOT00000024402
amyloid beta precursor protein binding family B member 1
chr8_-_115167486 10.79 ENSRNOT00000033018
G protein-coupled receptor 62
chr13_+_92569785 10.77 ENSRNOT00000082700
formin 2
chr6_-_141291347 10.76 ENSRNOT00000008333

chr10_+_83636518 10.73 ENSRNOT00000007352
phosphoethanolamine/phosphocholine phosphatase 1
chr12_+_28212333 10.73 ENSRNOT00000001182
autism susceptibility candidate 2
chr7_+_60099120 10.70 ENSRNOT00000007338
leucine-rich repeat-containing protein 10-like
chr17_-_23923792 10.56 ENSRNOT00000018739
glucose-fructose oxidoreductase domain containing 1
chr12_-_23954431 10.38 ENSRNOT00000001958
malate dehydrogenase 2
chr4_+_180291389 10.29 ENSRNOT00000002465
sarcospan
chr12_+_2534212 10.24 ENSRNOT00000001399
cortexin 1
chr4_-_103369224 10.14 ENSRNOT00000075709

chr8_+_65611570 10.12 ENSRNOT00000017147
La ribonucleoprotein domain family, member 6
chr5_+_76092287 10.06 ENSRNOT00000020207
zinc finger protein 483
chr5_+_148661070 9.99 ENSRNOT00000056229
Sodium/potassium transporting ATPase interacting 1
chr9_-_55673704 9.95 ENSRNOT00000066231
ENSRNOT00000081677
transmembrane protein with EGF-like and two follistatin-like domains 2
chr10_+_45258887 9.95 ENSRNOT00000048642
butyrophilin like 10
chr7_+_2752680 9.93 ENSRNOT00000033726
citrate synthase
chr20_+_5008508 9.87 ENSRNOT00000001153
von Willebrand factor A domain containing 7
chr7_-_119996824 9.76 ENSRNOT00000011079
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chrX_-_1714061 9.63 ENSRNOT00000011592
cyclin-dependent kinase 16
chr3_+_19495628 9.58 ENSRNOT00000077990
immunoglobulin kappa variable 4-57
chr5_-_168734296 9.57 ENSRNOT00000066120
calmodulin binding transcription activator 1
chr3_+_18970574 9.57 ENSRNOT00000088394

chrX_+_105239620 9.50 ENSRNOT00000085693
dystrophin related protein 2
chr8_-_117237229 9.46 ENSRNOT00000071381
kelch domain containing 8B
chr16_-_81945127 9.43 ENSRNOT00000023352
MCF.2 cell line derived transforming sequence-like
chr13_-_51183269 9.37 ENSRNOT00000039540
PTPRF interacting protein alpha 4
chr12_-_30728655 9.21 ENSRNOT00000035881
matrix metallopeptidase 17
chr18_+_30574627 9.20 ENSRNOT00000060484
protocadherin beta 19
chr1_+_221801524 9.20 ENSRNOT00000031227
neurexin 2
chr6_-_142676432 9.17 ENSRNOT00000074947

chr1_+_77994203 9.13 ENSRNOT00000002044
NSF attachment protein alpha
chr11_+_85430400 9.05 ENSRNOT00000083198

chr4_-_103646906 9.02 ENSRNOT00000047620

chr5_-_65073012 8.96 ENSRNOT00000007957
glutamate ionotropic receptor NMDA type subunit 3A
chrX_+_105500173 8.94 ENSRNOT00000040476
armadillo repeat containing, X-linked 4
chr11_+_85532526 8.83 ENSRNOT00000036565

chr15_+_4850122 8.82 ENSRNOT00000071133
G protein subunit gamma 2
chr20_-_2191640 8.82 ENSRNOT00000001016
tripartite motif-containing 10
chr5_+_159967839 8.81 ENSRNOT00000051317
heat shock protein family B (small) member 7
chr13_+_71107465 8.80 ENSRNOT00000003239
regulator of G-protein signaling 8
chr11_-_27971359 8.79 ENSRNOT00000085629
ENSRNOT00000051060
ENSRNOT00000042581
ENSRNOT00000050073
ENSRNOT00000081066
glutamate ionotropic receptor kainate type subunit 1
chr6_-_142635763 8.77 ENSRNOT00000048908

chr1_-_57815038 8.74 ENSRNOT00000075401
repulsive guidance molecule family member B
chr10_-_108691367 8.74 ENSRNOT00000005067
neuronal pentraxin 1
chr20_+_3558827 8.72 ENSRNOT00000088130
discoidin domain receptor tyrosine kinase 1
chr11_+_85508300 8.57 ENSRNOT00000038646

chr10_+_16635989 8.52 ENSRNOT00000028155
NK2 homeobox 5
chr6_-_99870024 8.49 ENSRNOT00000010043
RAB15, member RAS oncogene family
chr7_+_60087429 8.48 ENSRNOT00000073117
leucine-rich repeat-containing 10
chr18_+_4325875 8.43 ENSRNOT00000073771
impact RWD domain protein
chr1_-_261051498 8.31 ENSRNOT00000071417
Rho GTPase activating protein 19
chr10_-_15155412 8.26 ENSRNOT00000026536
hydroxyacylglutathione hydrolase-like
chr2_+_184230459 8.25 ENSRNOT00000074187

chr6_-_143065639 8.12 ENSRNOT00000070923

chr4_+_132137793 8.12 ENSRNOT00000014455
G protein-coupled receptor 27
chr2_+_34186091 8.11 ENSRNOT00000016129
small glutamine rich tetratricopeptide repeat containing beta
chr10_-_64657089 8.02 ENSRNOT00000080703
active BCR-related
chr1_-_59347472 8.01 ENSRNOT00000017718
leucyl and cystinyl aminopeptidase
chr17_-_31813716 7.95 ENSRNOT00000074147

chr11_+_85618714 7.92 ENSRNOT00000074614

chr15_-_33752665 7.90 ENSRNOT00000034102
zinc finger homeobox 2
chr19_-_37427989 7.89 ENSRNOT00000022863
tubulin polymerization-promoting protein family member 3
chr8_+_118066988 7.87 ENSRNOT00000056161
microtubule-associated protein 4
chr1_-_215846911 7.86 ENSRNOT00000089171
insulin-like growth factor 2
chr17_+_54181419 7.71 ENSRNOT00000023861
kinesin family member 5B
chr15_-_108898703 7.64 ENSRNOT00000067577
Zic family member 5
chr7_-_116255167 7.60 ENSRNOT00000038109
ENSRNOT00000041774
cytochrome P450, family 11, subfamily b, polypeptide 2
chr1_-_43638161 7.53 ENSRNOT00000024460
interaction protein for cytohesin exchange factors 1
chrX_-_2657155 7.52 ENSRNOT00000005630
carbohydrate sulfotransferase 7
chr2_+_187737770 7.48 ENSRNOT00000036143
ENSRNOT00000092611
ENSRNOT00000092620
progestin and adipoQ receptor family member 6
chr10_+_90348299 7.48 ENSRNOT00000089616
RUN domain containing 3A
chr11_+_85992696 7.42 ENSRNOT00000084433

chr1_+_79989019 7.42 ENSRNOT00000020428
dystrophia myotonica-protein kinase
chr5_+_127404450 7.40 ENSRNOT00000017575
LDL receptor related protein 8
chr6_+_137997335 7.39 ENSRNOT00000006872
transmembrane protein 121
chr17_+_31441630 7.32 ENSRNOT00000083705
ENSRNOT00000023582
tubulin, beta 2B class IIb
chr1_-_140860882 7.32 ENSRNOT00000067889
ENSRNOT00000024253
ENSRNOT00000079100
milk fat globule-EGF factor 8 protein
chr5_-_85123829 7.30 ENSRNOT00000007578
BMP/retinoic acid inducible neural specific 1
chr15_+_32386816 7.08 ENSRNOT00000060322

chr6_-_140407307 7.07 ENSRNOT00000079087

chr6_-_142880382 7.07 ENSRNOT00000074706
ENSRNOT00000072861

chr8_+_45797315 7.06 ENSRNOT00000059997

chrX_-_63961527 7.04 ENSRNOT00000071762
G1 to S phase transition 2
chr2_+_187988925 7.00 ENSRNOT00000093033
ENSRNOT00000093016
Rho/Rac guanine nucleotide exchange factor 2
chr3_+_19174027 6.99 ENSRNOT00000074445

chr1_-_14412807 6.94 ENSRNOT00000074583
TNF alpha induced protein 3
chr2_+_184243976 6.88 ENSRNOT00000042146
dual endothelin 1, angiotensin II receptor
chr6_+_139523337 6.86 ENSRNOT00000090711

chr6_-_143537030 6.82 ENSRNOT00000071876
rCG64220-like
chr16_+_23668595 6.81 ENSRNOT00000067886
pleckstrin and Sec7 domain containing 3
chr4_-_103761881 6.81 ENSRNOT00000084103

chr15_+_52241801 6.75 ENSRNOT00000082639
HR, lysine demethylase and nuclear receptor corepressor
chr20_-_29738506 6.72 ENSRNOT00000000697
carbohydrate sulfotransferase 3
chr2_+_182796728 6.70 ENSRNOT00000032351
protocadherin-16-like
chr11_-_1983513 6.64 ENSRNOT00000000907
5-hydroxytryptamine receptor 1F
chr5_+_142875773 6.57 ENSRNOT00000082120
ENSRNOT00000056496
EPH receptor A10
chr12_-_21760292 6.56 ENSRNOT00000059592
TSC22 domain family protein 4-like
chr10_-_94557764 6.52 ENSRNOT00000016841
sodium voltage-gated channel alpha subunit 4
chrX_+_135470915 6.51 ENSRNOT00000009637
solute carrier family 25 member 14
chr13_-_51784639 6.45 ENSRNOT00000089068
protein phosphatase 1, regulatory subunit 12B
chr6_+_139523495 6.41 ENSRNOT00000075467

chr20_+_22060224 6.37 ENSRNOT00000057992
zinc finger protein 365
chr2_+_207930796 6.37 ENSRNOT00000047827
potassium voltage-gated channel subfamily D member 3
chr10_+_70262361 6.35 ENSRNOT00000064625
ENSRNOT00000076973
unc-45 myosin chaperone B
chr2_-_211831551 6.34 ENSRNOT00000039225
ENSRNOT00000090561
family with sequence similarity 102, member B
chr1_-_72335855 6.30 ENSRNOT00000021613
coiled-coil domain containing 106
chr5_+_164808323 6.27 ENSRNOT00000011005
natriuretic peptide A
chr1_+_165237847 6.23 ENSRNOT00000022963
phosphoglucomutase 2-like 1
chr4_+_102403451 6.20 ENSRNOT00000071605

chr3_-_79018487 6.13 ENSRNOT00000080981
olfactory receptor 736
chr14_+_83724933 6.13 ENSRNOT00000029848
phospholipase A2, group III
chrX_+_14498119 6.12 ENSRNOT00000051135
X-linked Kx blood group
chr1_-_252550394 6.09 ENSRNOT00000083468
actin, alpha 2, smooth muscle, aorta
chr6_-_11494459 6.09 ENSRNOT00000021570
potassium two pore domain channel subfamily K member 12

Network of associatons between targets according to the STRING database.

First level regulatory network of Pax5

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
14.0 41.9 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
7.2 29.0 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
5.8 17.5 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
5.5 16.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
5.4 16.3 GO:0032470 positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470)
4.8 14.5 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
4.7 23.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
4.2 12.7 GO:0033693 neurofilament bundle assembly(GO:0033693)
4.2 41.8 GO:0016198 axon choice point recognition(GO:0016198)
4.0 19.9 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
3.7 51.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
3.6 10.8 GO:0070649 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
3.6 17.9 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
3.6 10.7 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
3.5 14.0 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
3.4 20.4 GO:0010625 positive regulation of Schwann cell proliferation(GO:0010625) regulation of chaperone-mediated autophagy(GO:1904714)
3.4 13.4 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
3.2 25.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
3.2 28.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
3.1 28.3 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
2.9 20.4 GO:0090527 actin filament reorganization(GO:0090527)
2.8 8.5 GO:0003285 atrioventricular node development(GO:0003162) right ventricular cardiac muscle tissue morphogenesis(GO:0003221) septum secundum development(GO:0003285) His-Purkinje system cell differentiation(GO:0060932)
2.8 17.0 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
2.8 8.4 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
2.8 11.0 GO:0031133 regulation of axon diameter(GO:0031133)
2.7 13.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
2.7 8.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
2.7 8.0 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
2.7 8.0 GO:0010813 neuropeptide catabolic process(GO:0010813)
2.6 7.9 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
2.6 7.9 GO:0051012 microtubule sliding(GO:0051012)
2.6 13.1 GO:0044691 tooth eruption(GO:0044691)
2.5 10.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
2.5 12.6 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
2.5 12.6 GO:0060005 vestibular reflex(GO:0060005)
2.5 14.9 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
2.4 16.9 GO:0050915 sensory perception of sour taste(GO:0050915)
2.3 6.9 GO:0034146 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
2.3 9.1 GO:0035494 SNARE complex disassembly(GO:0035494)
2.1 6.4 GO:0033566 gamma-tubulin complex localization(GO:0033566)
2.1 25.3 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
2.1 6.3 GO:1902304 positive regulation of potassium ion export(GO:1902304)
1.9 5.8 GO:0061744 motor behavior(GO:0061744)
1.9 3.9 GO:0070560 protein secretion by platelet(GO:0070560)
1.9 5.7 GO:1902276 pancreatic amylase secretion(GO:0036395) regulation of pancreatic amylase secretion(GO:1902276)
1.8 7.3 GO:0021767 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373)
1.8 9.1 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
1.8 16.1 GO:0097084 vascular smooth muscle cell development(GO:0097084)
1.8 7.0 GO:0002184 cytoplasmic translational termination(GO:0002184)
1.8 17.5 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
1.7 7.0 GO:0071802 negative regulation of podosome assembly(GO:0071802)
1.7 9.9 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
1.7 8.3 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
1.7 14.9 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
1.6 17.9 GO:0097113 AMPA glutamate receptor clustering(GO:0097113)
1.6 7.9 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.5 6.1 GO:0072144 glomerular mesangial cell development(GO:0072144)
1.5 6.0 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
1.5 6.0 GO:0097681 double-strand break repair via alternative nonhomologous end joining(GO:0097681)
1.5 7.4 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
1.4 23.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
1.4 6.9 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
1.4 39.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
1.3 10.7 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
1.3 4.0 GO:1990166 protein localization to site of double-strand break(GO:1990166)
1.3 2.6 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
1.3 7.9 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
1.3 26.1 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.3 5.2 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
1.3 11.4 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
1.3 3.8 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
1.3 5.0 GO:0010157 response to chlorate(GO:0010157)
1.2 18.6 GO:0048245 eosinophil chemotaxis(GO:0048245)
1.2 13.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
1.2 3.7 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
1.2 18.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
1.2 14.0 GO:0036005 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
1.2 20.8 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
1.1 3.4 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
1.1 3.2 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
1.1 9.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
1.0 7.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
1.0 15.4 GO:0035641 locomotory exploration behavior(GO:0035641)
1.0 10.9 GO:0007258 JUN phosphorylation(GO:0007258)
1.0 3.0 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
1.0 4.8 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.9 6.4 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.9 3.6 GO:0033122 negative regulation of purine nucleotide catabolic process(GO:0033122) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.9 8.8 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.9 4.4 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.9 10.4 GO:0006108 malate metabolic process(GO:0006108)
0.9 6.0 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.8 2.5 GO:1990091 sodium-dependent self proteolysis(GO:1990091)
0.8 3.4 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.8 22.4 GO:0007413 axonal fasciculation(GO:0007413)
0.8 6.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.8 6.5 GO:0015871 choline transport(GO:0015871)
0.8 4.0 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.8 4.0 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.8 8.7 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.8 9.4 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.8 8.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.8 2.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.8 2.3 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.8 6.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.8 3.8 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751) negative regulation of p38MAPK cascade(GO:1903753)
0.8 17.3 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.7 16.5 GO:0097320 membrane tubulation(GO:0097320)
0.7 3.7 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.7 5.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.7 5.7 GO:0002118 aggressive behavior(GO:0002118)
0.7 9.0 GO:0060134 prepulse inhibition(GO:0060134)
0.7 2.6 GO:0003419 growth plate cartilage chondrocyte proliferation(GO:0003419) sequestering of BMP in extracellular matrix(GO:0035582)
0.7 9.2 GO:0042756 drinking behavior(GO:0042756)
0.7 6.6 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.6 3.2 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.6 1.3 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.6 4.3 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.6 3.7 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.6 4.3 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.6 3.6 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.6 1.8 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.6 13.8 GO:0060384 innervation(GO:0060384)
0.6 20.7 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.6 26.3 GO:0007628 adult walking behavior(GO:0007628)
0.6 4.6 GO:0071233 cellular response to leucine(GO:0071233)
0.6 5.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.6 2.3 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
0.6 7.3 GO:0007614 short-term memory(GO:0007614) maternal behavior(GO:0042711)
0.6 3.9 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.6 2.2 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.5 2.7 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.5 2.7 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.5 3.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.5 5.9 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.5 8.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.5 3.3 GO:1901374 acetate ester transport(GO:1901374)
0.5 11.8 GO:0030252 growth hormone secretion(GO:0030252)
0.5 6.0 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.4 1.8 GO:1990859 response to endothelin(GO:1990839) cellular response to endothelin(GO:1990859)
0.4 4.9 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.4 1.3 GO:0060661 submandibular salivary gland formation(GO:0060661) positive regulation of hair follicle cell proliferation(GO:0071338)
0.4 6.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.4 3.9 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.4 8.8 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.4 12.9 GO:1904894 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.4 9.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.4 1.6 GO:1903999 defecation(GO:0030421) negative regulation of eating behavior(GO:1903999) regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.4 1.2 GO:0010796 regulation of multivesicular body size(GO:0010796) multivesicular body assembly(GO:0036258)
0.4 9.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.4 2.0 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.4 25.6 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.4 52.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.4 3.8 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.4 5.1 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.4 2.9 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.4 2.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.4 1.8 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.3 1.4 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.3 2.0 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.3 2.0 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.3 14.8 GO:0031103 axon regeneration(GO:0031103)
0.3 8.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.3 21.2 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.3 1.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.3 3.5 GO:0032341 aldosterone metabolic process(GO:0032341) aldosterone biosynthetic process(GO:0032342)
0.3 6.1 GO:0048266 behavioral response to pain(GO:0048266)
0.3 5.9 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.3 4.3 GO:0042118 endothelial cell activation(GO:0042118)
0.3 6.8 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.3 2.1 GO:0033131 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.3 0.9 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.3 3.3 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.3 3.5 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.3 39.5 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.3 3.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.3 18.3 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.3 2.5 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.3 2.7 GO:0030953 astral microtubule organization(GO:0030953)
0.3 0.8 GO:0070084 protein initiator methionine removal(GO:0070084)
0.3 1.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.2 3.2 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.2 3.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.2 5.8 GO:0017004 cytochrome complex assembly(GO:0017004)
0.2 4.1 GO:0031424 keratinization(GO:0031424)
0.2 1.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.2 2.9 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.2 0.7 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.2 24.2 GO:0009408 response to heat(GO:0009408)
0.2 5.6 GO:0031572 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.2 10.6 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.2 3.2 GO:0044804 nucleophagy(GO:0044804)
0.2 0.4 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.2 0.7 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.2 6.6 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.2 23.3 GO:0050808 synapse organization(GO:0050808)
0.2 3.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.2 1.5 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.2 1.1 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.2 4.0 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.2 5.2 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.2 2.8 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.2 4.8 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.2 0.8 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.2 0.7 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 1.0 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.2 4.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.2 2.6 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.2 0.7 GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.2 1.3 GO:0034214 protein hexamerization(GO:0034214)
0.2 1.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.2 0.3 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.1 1.8 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.1 1.3 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 6.4 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 4.2 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.4 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1 1.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.3 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.1 1.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 2.0 GO:0009629 response to gravity(GO:0009629)
0.1 4.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1 1.9 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 1.1 GO:0007097 nuclear migration(GO:0007097)
0.1 7.2 GO:0055013 cardiac muscle cell development(GO:0055013)
0.1 0.7 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 3.4 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.1 2.7 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.1 1.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 4.8 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 0.9 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 3.2 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 1.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 8.1 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 4.1 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1 0.3 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 4.1 GO:0046785 microtubule polymerization(GO:0046785)
0.1 2.8 GO:0006040 amino sugar metabolic process(GO:0006040)
0.1 1.8 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 0.2 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.1 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 0.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 3.8 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.1 0.3 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.4 GO:2001204 regulation of osteoclast development(GO:2001204)
0.1 20.2 GO:0007409 axonogenesis(GO:0007409)
0.1 0.6 GO:0046512 sphingosine biosynthetic process(GO:0046512)
0.1 1.8 GO:0008344 adult locomotory behavior(GO:0008344)
0.1 0.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 1.2 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0 0.7 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 2.4 GO:0051701 interaction with host(GO:0051701)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0002432 granuloma formation(GO:0002432)
0.0 0.8 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 1.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 2.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.5 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.2 GO:0033574 response to testosterone(GO:0033574)
0.0 0.2 GO:0097499 protein localization to nonmotile primary cilium(GO:0097499)
0.0 0.0 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.8 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.0 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.1 GO:0001302 replicative cell aging(GO:0001302)
0.0 1.0 GO:0006334 nucleosome assembly(GO:0006334)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
8.8 17.5 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
5.1 20.4 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
4.6 9.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
4.3 17.0 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
3.9 11.8 GO:0090534 longitudinal sarcoplasmic reticulum(GO:0014801) calcium ion-transporting ATPase complex(GO:0090534)
3.3 16.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
2.7 10.8 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
2.7 16.1 GO:0016012 sarcoglycan complex(GO:0016012)
2.6 15.4 GO:0097441 basilar dendrite(GO:0097441)
2.5 22.1 GO:0030314 junctional membrane complex(GO:0030314)
2.4 12.1 GO:0097454 Schwann cell microvillus(GO:0097454)
2.4 29.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
2.1 10.7 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
2.1 12.6 GO:0032280 symmetric synapse(GO:0032280)
1.9 44.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.8 7.0 GO:0018444 translation release factor complex(GO:0018444)
1.7 28.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
1.5 37.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
1.5 8.8 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
1.3 4.0 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
1.3 18.6 GO:0031045 dense core granule(GO:0031045)
1.2 6.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
1.2 12.7 GO:0097418 neurofibrillary tangle(GO:0097418)
1.1 17.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
1.0 9.1 GO:0071821 FANCM-MHF complex(GO:0071821)
1.0 11.9 GO:0005796 Golgi lumen(GO:0005796)
1.0 3.8 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.9 1.9 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.9 90.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.9 12.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.9 12.8 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
0.9 7.1 GO:0005869 dynactin complex(GO:0005869)
0.8 4.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.8 10.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.6 5.7 GO:0097470 ribbon synapse(GO:0097470)
0.6 3.5 GO:1990696 USH2 complex(GO:1990696)
0.6 4.6 GO:0031931 TORC1 complex(GO:0031931)
0.6 17.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.6 7.7 GO:0035253 ciliary rootlet(GO:0035253)
0.5 25.2 GO:0048786 presynaptic active zone(GO:0048786)
0.5 46.2 GO:0043195 terminal bouton(GO:0043195)
0.5 34.5 GO:0031594 neuromuscular junction(GO:0031594)
0.5 10.4 GO:0019013 viral nucleocapsid(GO:0019013)
0.4 7.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.4 69.2 GO:0043204 perikaryon(GO:0043204)
0.4 3.7 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.4 2.0 GO:0072534 perineuronal net(GO:0072534)
0.4 15.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.4 9.6 GO:0042629 mast cell granule(GO:0042629)
0.4 6.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.3 4.0 GO:0042405 nuclear inclusion body(GO:0042405)
0.3 6.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.3 2.3 GO:0071203 WASH complex(GO:0071203)
0.3 3.0 GO:0008385 IkappaB kinase complex(GO:0008385)
0.3 28.2 GO:0031225 anchored component of membrane(GO:0031225)
0.3 19.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.3 1.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 5.2 GO:0010369 chromocenter(GO:0010369)
0.2 4.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.2 2.8 GO:0005652 nuclear lamina(GO:0005652)
0.2 9.6 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.2 1.3 GO:0000322 storage vacuole(GO:0000322)
0.2 29.5 GO:0098793 presynapse(GO:0098793)
0.2 3.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 15.2 GO:0005884 actin filament(GO:0005884)
0.2 3.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 1.9 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 16.8 GO:0030427 site of polarized growth(GO:0030427)
0.2 4.4 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.2 7.3 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.2 23.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 7.6 GO:0002102 podosome(GO:0002102)
0.2 1.3 GO:0036449 microtubule minus-end(GO:0036449)
0.2 1.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 15.2 GO:0042383 sarcolemma(GO:0042383)
0.2 7.3 GO:0031672 A band(GO:0031672)
0.2 4.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 3.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 21.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.2 3.2 GO:0001891 phagocytic cup(GO:0001891)
0.2 72.9 GO:0030424 axon(GO:0030424)
0.2 5.2 GO:0014704 intercalated disc(GO:0014704)
0.2 0.8 GO:0005827 polar microtubule(GO:0005827)
0.2 4.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.2 3.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 30.4 GO:0043235 receptor complex(GO:0043235)
0.1 7.2 GO:0072686 mitotic spindle(GO:0072686)
0.1 2.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 2.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 3.0 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.1 2.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 3.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 3.7 GO:0016235 aggresome(GO:0016235)
0.1 0.7 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 1.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 5.7 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.1 0.7 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 15.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 3.8 GO:0031519 PcG protein complex(GO:0031519)
0.1 2.7 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 6.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 7.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 3.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 2.2 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 3.5 GO:0005902 microvillus(GO:0005902)
0.1 1.9 GO:0030686 90S preribosome(GO:0030686)
0.1 24.8 GO:0031966 mitochondrial membrane(GO:0031966)
0.1 10.0 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.9 GO:0016592 mediator complex(GO:0016592)
0.0 3.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 1.3 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.8 GO:0031902 late endosome membrane(GO:0031902)
0.0 4.5 GO:0045202 synapse(GO:0045202)
0.0 1.8 GO:0016605 PML body(GO:0016605)
0.0 8.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.8 GO:0005844 polysome(GO:0005844)
0.0 1.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0022624 proteasome accessory complex(GO:0022624)
0.0 0.2 GO:0005719 nuclear euchromatin(GO:0005719)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.4 51.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
6.1 30.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
5.1 15.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
5.0 15.0 GO:0001847 opsonin receptor activity(GO:0001847)
5.0 19.9 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
4.8 14.5 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
4.2 12.6 GO:1990763 arrestin family protein binding(GO:1990763)
4.0 16.2 GO:0016492 G-protein coupled neurotensin receptor activity(GO:0016492)
4.0 11.9 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
3.5 14.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
3.4 34.1 GO:1990239 steroid hormone binding(GO:1990239)
3.1 22.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
3.0 9.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
3.0 27.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
2.9 23.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
2.7 13.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
2.7 15.9 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
2.6 10.4 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
2.5 7.6 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
2.4 14.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) chondroitin sulfotransferase activity(GO:0034481)
2.1 19.2 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
2.1 14.9 GO:0001595 angiotensin receptor activity(GO:0001595)
2.0 9.9 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
1.9 7.7 GO:0099609 microtubule lateral binding(GO:0099609)
1.9 17.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
1.9 20.7 GO:0042577 lipid phosphatase activity(GO:0042577)
1.8 16.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
1.7 17.0 GO:0098988 G-protein coupled glutamate receptor activity(GO:0098988)
1.7 8.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
1.6 55.3 GO:0017075 syntaxin-1 binding(GO:0017075)
1.5 9.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
1.5 6.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
1.5 8.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
1.5 5.8 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
1.3 13.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
1.3 7.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
1.3 6.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
1.3 9.2 GO:0097109 neuroligin family protein binding(GO:0097109)
1.2 8.7 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.2 6.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
1.1 4.6 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
1.1 3.3 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
1.1 24.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
1.1 8.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
1.1 10.9 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.0 3.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
1.0 5.0 GO:0043559 insulin binding(GO:0043559)
1.0 9.0 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.9 3.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.9 5.4 GO:0017040 ceramidase activity(GO:0017040)
0.9 16.1 GO:0015643 toxic substance binding(GO:0015643)
0.9 2.6 GO:0016015 morphogen activity(GO:0016015)
0.9 5.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.9 20.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.9 3.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.8 43.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.8 12.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.8 30.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.8 3.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.8 4.5 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.7 7.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.7 13.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.7 4.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.7 10.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.7 18.6 GO:0042056 chemoattractant activity(GO:0042056)
0.7 8.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.6 3.2 GO:0005042 netrin receptor activity(GO:0005042)
0.6 6.8 GO:0042809 vitamin D receptor binding(GO:0042809)
0.6 21.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.6 4.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.6 7.0 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.6 11.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.6 13.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.5 5.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.5 6.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.5 11.4 GO:0031489 myosin V binding(GO:0031489)
0.5 1.4 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.5 3.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.5 1.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.5 6.6 GO:0051378 serotonin binding(GO:0051378)
0.5 8.8 GO:0031005 filamin binding(GO:0031005)
0.5 12.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.4 4.0 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.4 2.7 GO:0050815 phosphoserine binding(GO:0050815)
0.4 4.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.4 5.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.4 4.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.4 8.5 GO:0015026 coreceptor activity(GO:0015026)
0.4 4.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.4 3.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.4 53.7 GO:0005179 hormone activity(GO:0005179)
0.4 10.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.4 14.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.4 4.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.4 7.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.3 7.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.3 8.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 2.2 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.3 2.5 GO:0031432 titin binding(GO:0031432)
0.3 6.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.3 7.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 28.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.3 1.7 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.3 3.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 10.3 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.3 2.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 5.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.3 3.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.3 1.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.3 1.3 GO:0001155 TFIIIA-class transcription factor binding(GO:0001155)
0.3 1.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.3 5.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 1.8 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.3 6.0 GO:0070840 dynein complex binding(GO:0070840)
0.2 8.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 2.7 GO:0004887 thyroid hormone receptor activity(GO:0004887) thyroid hormone binding(GO:0070324)
0.2 15.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 4.0 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.2 3.2 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 8.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.2 2.9 GO:0005283 sodium:amino acid symporter activity(GO:0005283) glycine transmembrane transporter activity(GO:0015187)
0.2 21.6 GO:0044325 ion channel binding(GO:0044325)
0.2 1.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 0.4 GO:0070012 oligopeptidase activity(GO:0070012)
0.2 14.3 GO:0043621 protein self-association(GO:0043621)
0.2 1.9 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 2.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 18.9 GO:0031072 heat shock protein binding(GO:0031072)
0.2 1.5 GO:0016004 phospholipase activator activity(GO:0016004)
0.2 2.0 GO:0019966 interleukin-1 binding(GO:0019966)
0.2 8.0 GO:0030295 protein kinase activator activity(GO:0030295)
0.2 3.2 GO:0005123 death receptor binding(GO:0005123)
0.2 18.0 GO:0017124 SH3 domain binding(GO:0017124)
0.2 106.5 GO:0005509 calcium ion binding(GO:0005509)
0.2 1.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 4.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 3.1 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 1.6 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 8.4 GO:0043022 ribosome binding(GO:0043022)
0.1 3.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.9 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 1.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 2.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 11.3 GO:0002020 protease binding(GO:0002020)
0.1 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.1 1.0 GO:0070700 BMP receptor binding(GO:0070700)
0.1 1.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 2.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 5.8 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 1.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 1.9 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 1.9 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 4.4 GO:0005507 copper ion binding(GO:0005507)
0.1 1.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 3.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 14.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 1.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.7 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 1.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 5.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 8.8 GO:0015631 tubulin binding(GO:0015631)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.7 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.9 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 1.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.0 GO:0030515 snoRNA binding(GO:0030515)
0.0 5.9 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.1 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 1.0 GO:0019843 rRNA binding(GO:0019843)
0.0 0.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.0 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 1.0 GO:0005267 potassium channel activity(GO:0005267)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 30.3 PID REELIN PATHWAY Reelin signaling pathway
0.9 21.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.8 18.0 PID ARF 3PATHWAY Arf1 pathway
0.8 44.9 PID EPHB FWD PATHWAY EPHB forward signaling
0.7 8.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.6 4.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.6 7.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.5 13.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.5 7.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.5 16.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.4 11.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.4 11.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.4 13.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.4 13.9 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.4 8.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.3 6.3 PID AP1 PATHWAY AP-1 transcription factor network
0.3 4.0 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.3 3.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.3 8.3 PID RAS PATHWAY Regulation of Ras family activation
0.3 13.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.3 6.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.3 2.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 4.8 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.2 1.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.2 4.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 7.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 7.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 5.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 4.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 2.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 2.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 0.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 2.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 3.4 PID RHOA PATHWAY RhoA signaling pathway
0.1 0.4 PID INSULIN PATHWAY Insulin Pathway
0.1 0.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 0.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 9.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.4 PID ATR PATHWAY ATR signaling pathway
0.1 1.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 2.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 12.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.7 PID P73PATHWAY p73 transcription factor network
0.0 1.1 PID PDGFRB PATHWAY PDGFR-beta signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
1.7 33.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
1.3 51.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
1.1 20.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
1.1 19.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
1.0 18.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.9 20.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.8 11.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.8 15.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.8 7.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.8 17.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.7 10.9 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.7 8.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.7 29.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.7 14.0 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.7 9.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.6 24.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.6 14.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.6 7.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.5 14.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.5 12.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.5 6.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.5 7.9 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.4 7.6 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.4 7.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.4 6.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.4 9.7 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.4 5.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.3 13.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.3 8.1 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.3 31.4 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.3 13.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.3 3.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.3 2.7 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.3 5.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.3 8.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 6.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 20.0 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.2 4.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.2 3.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.2 1.8 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.2 2.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.2 1.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 5.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 7.0 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.1 5.8 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 6.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 2.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 16.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 3.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 3.1 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.1 4.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 6.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.0 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.3 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.1 6.4 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 1.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.3 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import