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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Osr2_Osr1

Z-value: 0.59

Motif logo

Transcription factors associated with Osr2_Osr1

Gene Symbol Gene ID Gene Info
ENSRNOG00000011136 odd-skipped related transciption factor 2
ENSRNOG00000004210 odd-skipped related transciption factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Osr1rn6_v1_chr6_+_35314444_35314444-0.196.2e-04Click!
Osr2rn6_v1_chr7_+_74047814_74047814-0.165.4e-03Click!

Activity profile of Osr2_Osr1 motif

Sorted Z-values of Osr2_Osr1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_181486090 37.27 ENSRNOT00000075453

chr4_-_50200328 21.48 ENSRNOT00000060530
aminoadipate-semialdehyde synthase
chr6_+_8284878 14.08 ENSRNOT00000009581
solute carrier family 3 member 1
chr4_+_68849033 10.15 ENSRNOT00000016912
maltase-glucoamylase
chr14_+_2050483 9.20 ENSRNOT00000000047
solute carrier family 26 member 1
chr9_+_9721105 9.00 ENSRNOT00000073042
ENSRNOT00000075494
complement C3
chr1_+_154131926 8.28 ENSRNOT00000035257
ferritin light chain 1-like
chr17_-_9762813 8.19 ENSRNOT00000033749
solute carrier family 34 member 1
chr2_+_235264219 7.97 ENSRNOT00000086245
complement factor I
chr2_-_5577369 7.48 ENSRNOT00000093420
nuclear receptor subfamily 2, group F, member 1
chr10_+_3411380 6.92 ENSRNOT00000004346
similar to RIKEN cDNA 2900011O08
chr2_-_192671059 6.88 ENSRNOT00000012174
small proline-rich protein 1A
chr7_-_145154131 6.57 ENSRNOT00000055271
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr17_+_76306585 6.51 ENSRNOT00000065978
dehydrogenase E1 and transketolase domain containing 1
chr8_+_117117430 6.09 ENSRNOT00000073247
glutathione peroxidase 1
chr15_+_18451144 6.06 ENSRNOT00000010260
acyl-CoA oxidase 2
chr3_+_119805941 5.92 ENSRNOT00000018584
adrenoceptor alpha 2B
chr13_+_89805962 5.81 ENSRNOT00000074035
thiosulfate sulfurtransferase like domain containing 1
chr1_+_48320802 5.71 ENSRNOT00000082903

chr20_-_31736212 5.55 ENSRNOT00000000662
similar to RIKEN cDNA 2010107G23
chr5_-_134526089 5.44 ENSRNOT00000013321
cytochrome P450, family 4, subfamily b, polypeptide 1
chr18_+_59748444 5.41 ENSRNOT00000024752
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr17_+_69634890 5.19 ENSRNOT00000029049
aldo-keto reductase family 1, member C13
chr4_-_123557501 5.18 ENSRNOT00000075042
ENSRNOT00000085966
aldehyde dehydrogenase 1 family, member L1
chr1_+_70222964 5.15 ENSRNOT00000050180
paternally expressed 3
chr1_+_248132090 5.08 ENSRNOT00000022056
interleukin 33
chr5_-_135025084 5.04 ENSRNOT00000018766
tetraspanin 1
chr3_-_151724654 5.02 ENSRNOT00000026964
RNA binding motif protein 39
chr13_+_89643881 4.92 ENSRNOT00000004735
beta-1,4-galactosyltransferase 3
chr1_+_166564664 4.82 ENSRNOT00000090959
phosphodiesterase 2A
chr3_-_152259156 4.68 ENSRNOT00000065729
RNA-binding protein 39-like
chr10_-_59892960 4.65 ENSRNOT00000084432
aspartoacylase
chr1_+_91363492 4.63 ENSRNOT00000014517
CCAAT/enhancer binding protein alpha
chr18_-_48384645 4.61 ENSRNOT00000023485
peptidylprolyl isomerase C
chr8_+_48571323 4.55 ENSRNOT00000059776
coiled-coil domain containing 153
chr18_+_32273770 4.53 ENSRNOT00000087408
fibroblast growth factor 1
chr2_-_35104963 4.38 ENSRNOT00000018058
regulator of G-protein signaling 7-binding protein
chr6_-_42473738 4.32 ENSRNOT00000033327
potassium voltage-gated channel modifier subfamily F member 1
chr6_+_10348308 4.28 ENSRNOT00000034991
endothelial PAS domain protein 1
chrX_+_32232142 4.26 ENSRNOT00000047354
carbonic anhydrase 5B
chr18_+_16616937 4.24 ENSRNOT00000093641
molybdenum cofactor sulfurase
chr3_-_150108898 4.24 ENSRNOT00000022914
peroxisomal membrane protein 4
chr15_-_18675431 4.18 ENSRNOT00000080794
abhydrolase domain containing 6
chrX_-_75566481 4.12 ENSRNOT00000003714
zinc finger, DHHC-type containing 15
chr5_+_152708775 4.10 ENSRNOT00000022713
progestin and adipoQ receptor family member 7
chr10_+_68173369 4.01 ENSRNOT00000037072
transmembrane protein 98
chr10_+_58342393 3.83 ENSRNOT00000010358
WSC domain containing 1
chr19_-_40925660 3.74 ENSRNOT00000023645
MTSS1L, I-BAR domain containing
chr2_+_58724855 3.68 ENSRNOT00000089609
calcyphosine-like
chr8_-_117366096 3.68 ENSRNOT00000027411
WD repeat domain 6
chr2_+_247299433 3.65 ENSRNOT00000050330
unc-5 netrin receptor C
chr1_-_173682226 3.57 ENSRNOT00000020137
RIC3 acetylcholine receptor chaperone
chr7_-_102298522 3.56 ENSRNOT00000006273
alpha-1-B glycoprotein
chr14_+_71533460 3.56 ENSRNOT00000084274
prominin 1
chr11_-_82810014 3.56 ENSRNOT00000083539
mitogen-activated protein kinase kinase kinase 13
chr1_+_266380973 3.54 ENSRNOT00000080509
WW domain binding protein 1-like
chr1_+_162817611 3.53 ENSRNOT00000091952
p21 (RAC1) activated kinase 1
chr4_-_171591882 3.51 ENSRNOT00000009328
epidermal growth factor receptor pathway substrate 8
chrX_+_68782872 3.48 ENSRNOT00000075995
StAR-related lipid transfer domain containing 8
chr14_+_89253373 3.45 ENSRNOT00000035922
hypothetical protein LOC688553
chr4_+_180123905 3.43 ENSRNOT00000083173
Ras association domain family member 8
chr18_-_58423196 3.31 ENSRNOT00000025556
piezo-type mechanosensitive ion channel component 2
chrX_+_35599258 3.30 ENSRNOT00000072627
ENSRNOT00000005061
cyclin-dependent kinase-like 5
chr11_+_69484293 3.30 ENSRNOT00000049292
kalirin, RhoGEF kinase
chr1_+_31545631 3.27 ENSRNOT00000018336
succinate dehydrogenase complex flavoprotein subunit A
chr18_+_31444472 3.23 ENSRNOT00000075159
ring finger protein 14
chr1_-_87468288 3.19 ENSRNOT00000042207
signal-induced proliferation-associated 1 like 3
chr1_+_256101903 3.18 ENSRNOT00000022384
hematopoietically expressed homeobox
chr2_+_45104305 3.18 ENSRNOT00000014559
endothelial cell-specific molecule 1
chr13_+_35554964 3.16 ENSRNOT00000072632
transmembrane protein 185B
chr9_+_90857308 3.07 ENSRNOT00000073993
collagen alpha-3(IV) chain-like
chr10_-_70788309 3.07 ENSRNOT00000029184
chemokine (C-C motif) ligand 9
chr15_+_93634820 2.99 ENSRNOT00000093318
ceroid-lipofuscinosis, neuronal 5
chr1_+_141832774 2.98 ENSRNOT00000073302
fucose mutarotase
chrX_+_156355376 2.95 ENSRNOT00000078304
L antigen family, member 3
chr9_-_11080155 2.94 ENSRNOT00000072830
fibronectin type III and SPRY domain containing 1
chr5_+_154310453 2.92 ENSRNOT00000013322
UDP-galactose-4-epimerase
chr11_-_31892531 2.91 ENSRNOT00000033745
crystallin zeta like 1
chr11_+_71222600 2.79 ENSRNOT00000002418
mucin 20, cell surface associated
chr10_+_58860940 2.69 ENSRNOT00000056551
ENSRNOT00000074523
XIAP associated factor-1
chr1_+_61522298 2.64 ENSRNOT00000029111
zinc finger protein 51
chr2_+_125752130 2.60 ENSRNOT00000038703
FAT atypical cadherin 4
chr13_-_89242443 2.59 ENSRNOT00000029202
activating transcription factor 6
chr10_+_95242986 2.57 ENSRNOT00000065589
ENSRNOT00000080460
similar to hypothetical protein LOC284018 isoform b
chr10_-_59049482 2.56 ENSRNOT00000078272
spinster homolog 2
chr2_-_26011429 2.55 ENSRNOT00000065143
Rho guanine nucleotide exchange factor 28
chr8_-_21523540 2.50 ENSRNOT00000085060
zinc finger protein 266
chr7_+_101069104 2.47 ENSRNOT00000056894

chr9_-_89193821 2.44 ENSRNOT00000090881
SPHK1 interactor, AKAP domain containing
chr12_+_42097626 2.42 ENSRNOT00000001893
T-box 5
chr3_+_138597638 2.36 ENSRNOT00000031623
zinc finger protein 133
chr6_+_137953545 2.34 ENSRNOT00000006804
cysteine-rich protein 2
chr10_+_37724915 2.29 ENSRNOT00000008477
voltage-dependent anion channel 1
chr20_+_13836030 2.19 ENSRNOT00000093157
ENSRNOT00000001659
calcineurin binding protein 1
chr10_+_47282208 2.18 ENSRNOT00000057953
potassium voltage-gated channel subfamily J member 12
chr1_-_234749447 2.17 ENSRNOT00000016930
nicotinamide riboside kinase 1
chr11_-_74315248 2.16 ENSRNOT00000002346
hes family bHLH transcription factor 1
chr10_+_47281786 2.16 ENSRNOT00000089123
potassium voltage-gated channel subfamily J member 12
chr20_-_11815647 2.15 ENSRNOT00000001639
integrin subunit beta 2
chr1_-_240601744 2.13 ENSRNOT00000024093
aldehyde dehydrogenase family 1, subfamily A7
chr15_-_51400606 2.12 ENSRNOT00000023318
charged multivesicular body protein 7
chr2_-_119007835 2.08 ENSRNOT00000087803
G protein subunit beta 4
chr1_+_252894663 2.07 ENSRNOT00000054757
interferon-induced protein with tetratricopeptide repeats 2
chr18_-_4294136 2.05 ENSRNOT00000091909
oxysterol binding protein-like 1A
chr2_+_76923591 2.04 ENSRNOT00000042759
signal-regulatory protein alpha-like
chr6_+_127333590 2.04 ENSRNOT00000063970
interferon, alpha-inducible protein 27
chr8_-_102149912 2.02 ENSRNOT00000011263
similar to Ab2-095
chr19_-_955626 1.98 ENSRNOT00000017774
brain expressed, associated with NEDD4, 1
chr19_-_43528851 1.98 ENSRNOT00000036972
mixed lineage kinase domain like pseudokinase
chr10_-_56276764 1.97 ENSRNOT00000049048
eukaryotic translation initiation factor 4A1
chr9_-_61418679 1.96 ENSRNOT00000078800
ankyrin repeat domain 44
chr1_-_73682247 1.96 ENSRNOT00000079498
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr3_+_92640752 1.96 ENSRNOT00000007604
solute carrier family 1 member 2
chr2_-_44379438 1.95 ENSRNOT00000073469
interleukin 31 receptor A
chr7_+_11356118 1.91 ENSRNOT00000041325
ATCAY, caytaxin
chr5_+_18901039 1.89 ENSRNOT00000012066
family with sequence similarity 110, member B
chr17_+_76532611 1.87 ENSRNOT00000024099
calcium/calmodulin-dependent protein kinase ID
chr5_+_147661618 1.87 ENSRNOT00000011054
BSD domain containing 1
chr2_+_4942775 1.85 ENSRNOT00000093548
ENSRNOT00000093741
family with sequence similarity 172, member A
chr7_-_15073052 1.85 ENSRNOT00000037708
zinc finger protein 799
chr6_+_113898420 1.83 ENSRNOT00000064872
neurexin 3
chr20_+_48881194 1.82 ENSRNOT00000000304
reticulon 4 interacting protein 1
chr1_+_53874860 1.76 ENSRNOT00000090486
t-complex-associated testis expressed 2
chr8_+_4440876 1.74 ENSRNOT00000049325
ENSRNOT00000076529
ENSRNOT00000076748
platelet derived growth factor D
chr2_+_159138758 1.71 ENSRNOT00000087942

chrX_+_40258493 1.71 ENSRNOT00000033010
membrane-bound transcription factor peptidase, site 2
chr1_+_64928503 1.68 ENSRNOT00000086274
vomeronasal 2 receptor, 80
chrX_-_159891326 1.68 ENSRNOT00000001154
RNA binding motif protein, X-linked
chr11_+_38727048 1.67 ENSRNOT00000081537
zinc finger protein 260-like
chr17_-_14687408 1.64 ENSRNOT00000088542

chr17_+_81798756 1.64 ENSRNOT00000066826
calcium voltage-gated channel auxiliary subunit beta 2
chr8_+_107875991 1.64 ENSRNOT00000090299
DAZ interacting zinc finger protein 1-like
chr7_-_57816621 1.62 ENSRNOT00000090748

chr1_-_250626844 1.58 ENSRNOT00000077135
N-acylsphingosine amidohydrolase 2
chr4_+_88271061 1.56 ENSRNOT00000087374
vomeronasal 1 receptor 86
chr1_-_60407295 1.55 ENSRNOT00000078350
vomeronasal 1 receptor 12
chr1_+_64849657 1.54 ENSRNOT00000081724
ENSRNOT00000086867
vomeronasal 2 receptor, 12
chr1_-_199341302 1.53 ENSRNOT00000073596
vitamin K epoxide reductase complex, subunit 1
chr8_-_109576353 1.53 ENSRNOT00000010320
protein phosphatase 2, regulatory subunit B'', alpha
chr3_+_72134731 1.51 ENSRNOT00000083592
yippee-like 4
chr1_+_170578889 1.49 ENSRNOT00000025906
integrin-linked kinase
chr2_-_80408672 1.47 ENSRNOT00000067638
family with sequence similarity 105, member A
chr15_+_105640097 1.46 ENSRNOT00000014300
muscleblind-like splicing regulator 2
chr1_-_216971183 1.46 ENSRNOT00000077911
MAS related GPR family member E
chr2_-_45077219 1.45 ENSRNOT00000014319
granzyme K
chr7_+_37101391 1.44 ENSRNOT00000029764
early endosome antigen 1
chrX_-_83151511 1.44 ENSRNOT00000057378
highly divergent homeobox
chr8_-_107952530 1.41 ENSRNOT00000052043
claudin 18
chr5_-_4972124 1.40 ENSRNOT00000081661
XK related 9
chr11_+_34316295 1.39 ENSRNOT00000081834
single-minded family bHLH transcription factor 2
chr1_-_31545559 1.39 ENSRNOT00000017779
coiled-coil domain containing 127
chr18_+_62805410 1.39 ENSRNOT00000086679
G protein subunit alpha L
chr1_-_212568224 1.38 ENSRNOT00000024976
fucose mutarotase-like
chr5_+_64053946 1.37 ENSRNOT00000011622
inversin
chr12_+_19512591 1.35 ENSRNOT00000060024
similar to family with sequence similarity 55, member C
chr1_-_142183884 1.33 ENSRNOT00000016032
FES proto-oncogene, tyrosine kinase
chr12_-_19439977 1.33 ENSRNOT00000060035
neurexophilin and PC-esterase domain family, member 5
chr5_-_2803855 1.32 ENSRNOT00000009490
ribosomal protein S8-like
chrX_+_123350346 1.32 ENSRNOT00000017026
solute carrier family 25, member 43
chr12_-_30770791 1.31 ENSRNOT00000093734
splicing factor SWAP homolog
chr12_-_19440501 1.29 ENSRNOT00000060048
neurexophilin and PC-esterase domain family, member 5
chr2_+_206342066 1.29 ENSRNOT00000026556
protein tyrosine phosphatase, non-receptor type 22
chr7_+_118502676 1.29 ENSRNOT00000005925
COMM domain containing 5
chr10_-_56850085 1.28 ENSRNOT00000025767
ribonuclease K
chr8_+_50200069 1.28 ENSRNOT00000023677
proprotein convertase subtilisin/kexin type 7
chr10_+_59529785 1.27 ENSRNOT00000064840
ENSRNOT00000065181
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr5_+_116420690 1.23 ENSRNOT00000087089
nuclear factor I/A
chr5_+_74649765 1.23 ENSRNOT00000075952
paralemmin 2
chrX_-_20807216 1.21 ENSRNOT00000075757
family with sequence similarity 156, member B
chr2_+_196608496 1.20 ENSRNOT00000091681
aryl hydrocarbon receptor nuclear translocator
chr2_-_188553289 1.19 ENSRNOT00000088822
tripartite motif-containing 46
chr14_-_114047527 1.19 ENSRNOT00000083199

chr1_+_202770775 1.19 ENSRNOT00000027704
WD repeat domain 11
chr2_-_149325913 1.19 ENSRNOT00000036690
G protein-coupled receptor 171
chr12_+_19513100 1.18 ENSRNOT00000030161
similar to family with sequence similarity 55, member C
chr10_-_56849255 1.13 ENSRNOT00000025491
similar to RIKEN cDNA 1110020A23
chr13_+_92146586 1.12 ENSRNOT00000004659
olfactory receptor 1588
chr4_+_7258176 1.11 ENSRNOT00000061992
transmembrane and ubiquitin-like domain containing 1
chr1_-_74638587 1.11 ENSRNOT00000046047
vomeronasal 2 receptor, 30
chr8_-_112807598 1.11 ENSRNOT00000015344
DnaJ heat shock protein family (Hsp40) member C13
chr3_-_77525518 1.10 ENSRNOT00000049513
olfactory receptor 663
chr6_-_146470456 1.10 ENSRNOT00000018479
similar to KIAA0825 protein
chr9_+_17122284 1.10 ENSRNOT00000077749
RNA polymerase I subunit C
chr5_-_2037038 1.09 ENSRNOT00000008680
transmembrane protein 70
chr15_+_35504845 1.09 ENSRNOT00000075687
olfactory receptor 1297
chr4_-_163445302 1.02 ENSRNOT00000087106
killer cell lectin-like receptor subfamily C, member 3
chr9_-_24451435 1.00 ENSRNOT00000060805
defensin beta 49
chr10_+_15696824 0.99 ENSRNOT00000079290
interleukin 9 receptor
chr4_-_163445136 0.98 ENSRNOT00000080299
killer cell lectin-like receptor subfamily C, member 3
chr4_+_1566448 0.98 ENSRNOT00000088227
olfactory receptor 1243
chr10_+_7041510 0.97 ENSRNOT00000003514
calcium regulated heat stable protein 1
chr2_+_225645568 0.93 ENSRNOT00000017878
ATP binding cassette subfamily A member 4
chr8_-_43796224 0.90 ENSRNOT00000084315
olfactory receptor 1330
chr9_+_98113346 0.88 ENSRNOT00000026912
prolactin releasing hormone
chr7_-_130408187 0.88 ENSRNOT00000015374
choline kinase beta
chr4_-_163423628 0.87 ENSRNOT00000079526
killer cell lectin-like receptor subfamily C, member 3
chr6_+_128738388 0.83 ENSRNOT00000050204
ribosomal protein L6, pseudogene 1
chr13_-_101697684 0.82 ENSRNOT00000078834
BRO1 domain and CAAX motif containing
chr17_+_44522140 0.79 ENSRNOT00000080490
histone H4 variant H4-v.1
chr1_-_73733788 0.77 ENSRNOT00000025338
leukocyte receptor cluster member 8

Network of associatons between targets according to the STRING database.

First level regulatory network of Osr2_Osr1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 21.5 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
3.0 9.0 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
2.7 8.2 GO:2000118 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
2.0 6.1 GO:0009609 response to symbiotic bacterium(GO:0009609)
2.0 6.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
1.8 5.4 GO:1990743 protein sialylation(GO:1990743)
1.7 5.2 GO:0009397 folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
1.7 6.9 GO:1903976 negative regulation of glial cell migration(GO:1903976)
1.5 5.9 GO:0035625 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
1.3 5.1 GO:0051025 microglial cell activation involved in immune response(GO:0002282) negative regulation of immunoglobulin secretion(GO:0051025) macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518)
1.2 3.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
1.1 3.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
1.1 3.2 GO:0061010 gall bladder development(GO:0061010)
1.1 3.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
1.0 4.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.9 4.5 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.9 3.6 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.9 3.5 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.9 2.6 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.9 4.3 GO:0048625 myoblast fate commitment(GO:0048625)
0.8 5.4 GO:0018879 biphenyl metabolic process(GO:0018879)
0.7 3.0 GO:0006004 fucose metabolic process(GO:0006004)
0.7 2.2 GO:0045608 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974) negative regulation of forebrain neuron differentiation(GO:2000978)
0.7 4.8 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.7 3.4 GO:0034334 adherens junction maintenance(GO:0034334)
0.7 3.3 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.6 1.9 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.6 3.7 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.6 1.7 GO:2000437 regulation of monocyte extravasation(GO:2000437)
0.6 7.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.6 1.7 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.5 1.6 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.5 9.2 GO:1902358 oxalate transport(GO:0019532) sulfate transmembrane transport(GO:1902358)
0.5 4.6 GO:0000050 urea cycle(GO:0000050)
0.5 1.5 GO:0090247 cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
0.5 3.0 GO:1904426 positive regulation of GTP binding(GO:1904426)
0.5 2.4 GO:0051891 positive regulation of cardioblast differentiation(GO:0051891)
0.5 1.4 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.4 1.3 GO:0071613 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165) negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.4 2.1 GO:0035106 operant conditioning(GO:0035106)
0.4 2.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.4 4.2 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.4 1.5 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.4 1.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.4 2.9 GO:0019388 galactose catabolic process(GO:0019388)
0.3 1.4 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.3 6.9 GO:0031424 keratinization(GO:0031424)
0.3 4.1 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.3 1.9 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.3 0.9 GO:0006649 phospholipid transfer to membrane(GO:0006649)
0.3 6.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.3 4.6 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.3 8.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.3 0.8 GO:0002148 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
0.3 2.5 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 0.7 GO:0019541 propionate metabolic process(GO:0019541)
0.2 2.6 GO:0048069 eye pigmentation(GO:0048069)
0.2 0.9 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.2 0.6 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.2 2.6 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.2 2.8 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.2 2.6 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.2 1.3 GO:0072014 proximal tubule development(GO:0072014)
0.2 2.0 GO:0035743 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
0.2 1.4 GO:0009405 pathogenesis(GO:0009405)
0.2 2.1 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.2 0.8 GO:0071104 response to interleukin-9(GO:0071104)
0.2 1.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 2.3 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.2 2.1 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 0.7 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 2.2 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 4.3 GO:0010107 potassium ion import(GO:0010107)
0.1 0.4 GO:0002677 peripheral T cell tolerance induction(GO:0002458) peripheral tolerance induction(GO:0002465) negative regulation of chronic inflammatory response(GO:0002677) negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.1 4.3 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 1.2 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.1 0.3 GO:0072752 cellular response to rapamycin(GO:0072752)
0.1 0.5 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 3.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 1.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 3.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 1.2 GO:0072189 ureter development(GO:0072189)
0.1 1.8 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 3.2 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.1 4.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 3.7 GO:0097178 ruffle assembly(GO:0097178)
0.1 1.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 1.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.9 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 3.7 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.1 3.0 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.1 1.1 GO:2000641 regulation of early endosome to late endosome transport(GO:2000641)
0.1 3.6 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 4.8 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.1 1.2 GO:0099612 protein localization to axon(GO:0099612)
0.1 2.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 2.0 GO:0070266 necroptotic process(GO:0070266)
0.1 1.4 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1 3.3 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.1 2.0 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.1 4.6 GO:0005977 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.1 0.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.6 GO:0035865 cellular response to potassium ion(GO:0035865)
0.1 3.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 2.1 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 2.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 1.3 GO:0009303 rRNA transcription(GO:0009303)
0.0 2.0 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 1.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 5.0 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 1.1 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 1.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:1902211 regulation of prolactin signaling pathway(GO:1902211)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.6 GO:0032620 interleukin-17 production(GO:0032620)
0.0 0.1 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 1.4 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.3 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 3.3 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 3.6 GO:0006865 amino acid transport(GO:0006865)
0.0 0.4 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 6.9 GO:0006397 mRNA processing(GO:0006397)
0.0 1.0 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 1.8 GO:0050773 regulation of dendrite development(GO:0050773)
0.0 3.3 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 1.1 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 1.6 GO:0006665 sphingolipid metabolic process(GO:0006665)
0.0 2.5 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 1.2 GO:0008360 regulation of cell shape(GO:0008360)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
1.5 4.6 GO:0036488 CHOP-C/EBP complex(GO:0036488)
1.3 6.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
1.2 6.1 GO:0097413 Lewy body(GO:0097413)
1.1 3.3 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
0.9 3.6 GO:0071914 prominosome(GO:0071914)
0.6 3.2 GO:0061689 tricellular tight junction(GO:0061689)
0.5 1.4 GO:0097543 ciliary inversin compartment(GO:0097543)
0.3 1.7 GO:0044530 supraspliceosomal complex(GO:0044530)
0.3 3.3 GO:0044294 dendritic growth cone(GO:0044294)
0.3 2.1 GO:0000815 ESCRT III complex(GO:0000815)
0.3 3.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 1.4 GO:0044308 axonal spine(GO:0044308)
0.2 1.2 GO:1990769 proximal neuron projection(GO:1990769)
0.2 6.4 GO:0001533 cornified envelope(GO:0001533)
0.2 3.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 17.6 GO:0031526 brush border membrane(GO:0031526)
0.2 3.5 GO:0071437 invadopodium(GO:0071437)
0.2 1.1 GO:0071203 WASH complex(GO:0071203)
0.2 2.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 3.3 GO:0005775 vacuolar lumen(GO:0005775)
0.1 1.1 GO:0016589 NURF complex(GO:0016589)
0.1 6.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.4 GO:0044609 DBIRD complex(GO:0044609)
0.1 4.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.7 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 12.6 GO:0072562 blood microparticle(GO:0072562)
0.1 1.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 4.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.0 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 2.2 GO:0008305 integrin complex(GO:0008305)
0.1 2.3 GO:0046930 pore complex(GO:0046930)
0.1 2.8 GO:0009925 basal plasma membrane(GO:0009925)
0.1 4.2 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 2.0 GO:0030673 axolemma(GO:0030673)
0.1 4.3 GO:0030315 T-tubule(GO:0030315)
0.1 3.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 5.1 GO:0005776 autophagosome(GO:0005776)
0.1 2.2 GO:0016235 aggresome(GO:0016235)
0.1 0.8 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 10.9 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 9.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 4.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 4.1 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 3.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 10.5 GO:0016607 nuclear speck(GO:0016607)
0.0 7.9 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 2.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 2.6 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 52.0 GO:0070062 extracellular exosome(GO:0070062)
0.0 2.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.9 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.1 GO:0055037 recycling endosome(GO:0055037)
0.0 6.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 15.5 GO:0005739 mitochondrion(GO:0005739)
0.0 1.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.0 GO:0031714 C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
2.5 10.1 GO:0016160 amylase activity(GO:0016160)
2.2 6.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
2.0 5.9 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
1.8 5.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
1.6 4.9 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
1.6 8.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
1.5 4.6 GO:0019807 aspartoacylase activity(GO:0019807)
1.3 26.7 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
1.2 6.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
1.2 4.8 GO:0036004 GAF domain binding(GO:0036004)
1.1 3.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
1.1 4.2 GO:0008265 Mo-molybdopterin cofactor sulfurase activity(GO:0008265)
1.1 3.2 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.9 7.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.8 6.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.7 3.0 GO:0042806 fucose binding(GO:0042806)
0.7 3.7 GO:0005042 netrin receptor activity(GO:0005042)
0.7 2.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.7 4.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.6 9.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.5 4.6 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.5 1.5 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.4 2.6 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.4 1.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.4 2.0 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.4 2.3 GO:0017040 ceramidase activity(GO:0017040)
0.4 3.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.3 4.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 4.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 5.4 GO:0015643 toxic substance binding(GO:0015643)
0.3 1.6 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 7.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.3 3.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.3 2.9 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.3 6.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.3 3.7 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.3 4.5 GO:0044548 S100 protein binding(GO:0044548)
0.2 11.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 2.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.2 3.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 0.6 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.2 2.2 GO:0008432 JUN kinase binding(GO:0008432)
0.2 4.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.2 3.6 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 0.9 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.2 0.9 GO:0004103 choline kinase activity(GO:0004103)
0.2 2.6 GO:0035497 cAMP response element binding(GO:0035497)
0.2 3.0 GO:0005537 mannose binding(GO:0005537)
0.1 8.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.9 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 4.1 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 4.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 1.1 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 1.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 2.3 GO:0015288 porin activity(GO:0015288)
0.1 1.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 3.2 GO:0050681 androgen receptor binding(GO:0050681)
0.1 3.1 GO:0008009 chemokine activity(GO:0008009) CCR chemokine receptor binding(GO:0048020)
0.1 1.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.2 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.1 3.6 GO:0042805 actinin binding(GO:0042805)
0.1 6.2 GO:0005496 steroid binding(GO:0005496)
0.1 3.8 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 1.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.9 GO:0050699 WW domain binding(GO:0050699)
0.1 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 3.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 1.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.7 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 1.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 2.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 3.3 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.2 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
0.0 2.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.8 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.1 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 3.2 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 4.4 GO:0005125 cytokine activity(GO:0005125)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 2.0 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.2 GO:0008312 7S RNA binding(GO:0008312)
0.0 1.3 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 14.1 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.7 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 1.4 GO:0048029 monosaccharide binding(GO:0048029)
0.0 2.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 2.1 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.2 GO:0019955 cytokine binding(GO:0019955)
0.0 2.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 4.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 6.9 GO:0016491 oxidoreductase activity(GO:0016491)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 7.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 3.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 5.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 0.7 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 3.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 0.7 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 3.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 1.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 4.5 PID FGF PATHWAY FGF signaling pathway
0.1 4.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.6 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 1.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 3.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 2.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.0 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 2.8 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 2.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 1.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 2.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 6.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 1.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.8 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 10.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
1.2 17.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.6 6.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.6 10.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.4 1.6 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.4 6.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.3 4.5 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.3 4.3 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.3 11.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 2.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.3 19.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 1.4 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 4.9 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.2 4.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 4.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 5.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 3.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 1.2 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.2 1.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 5.9 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.2 4.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 6.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 21.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 2.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 2.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 6.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 4.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 4.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 3.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 3.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 2.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 0.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 2.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.7 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 2.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 2.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.7 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 1.7 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 2.1 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates