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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Olig2_Olig3

Z-value: 0.74

Motif logo

Transcription factors associated with Olig2_Olig3

Gene Symbol Gene ID Gene Info
ENSRNOG00000028658 oligodendrocyte lineage transcription factor 2
ENSRNOG00000012057 oligodendrocyte transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Olig2rn6_v1_chr11_+_31389514_31389514-0.163.8e-03Click!
Olig3rn6_v1_chr1_+_14797766_14797766-0.107.9e-02Click!

Activity profile of Olig2_Olig3 motif

Sorted Z-values of Olig2_Olig3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_139486775 18.15 ENSRNOT00000077771

chr1_-_227175096 16.96 ENSRNOT00000054811

chr20_-_5212624 13.23 ENSRNOT00000074261
antigen peptide transporter 2
chr4_-_103024841 12.95 ENSRNOT00000090283

chr6_+_139486942 12.64 ENSRNOT00000080320

chr10_+_19366793 12.54 ENSRNOT00000050610
family with sequence similarity 196, member B
chr4_-_183417667 12.53 ENSRNOT00000089160
family with sequence similarity 60, member A
chr6_-_44363915 12.38 ENSRNOT00000085925
inhibitor of DNA binding 2, HLH protein
chr8_+_5768811 12.38 ENSRNOT00000013936
matrix metallopeptidase 8
chr3_+_20007192 12.37 ENSRNOT00000075229

chr4_-_155923079 12.12 ENSRNOT00000013308
C-type lectin domain family 4, member A3
chr1_-_198128857 11.43 ENSRNOT00000026496
coronin 1A
chr2_-_41871858 11.19 ENSRNOT00000039720
Grb2-binding adaptor protein, transmembrane
chr2_-_54777729 11.07 ENSRNOT00000082548
complement C7
chr4_-_103258134 10.87 ENSRNOT00000086827

chrX_-_23187341 10.73 ENSRNOT00000000180
5'-aminolevulinate synthase 2
chr5_+_59783890 10.66 ENSRNOT00000066277
maternal embryonic leucine zipper kinase
chr1_-_80744831 10.64 ENSRNOT00000025913
B-cell CLL/lymphoma 3
chr6_-_141291347 10.45 ENSRNOT00000008333

chr9_+_67763897 10.01 ENSRNOT00000071226
inducible T-cell co-stimulator
chrX_+_105147534 9.94 ENSRNOT00000046288
centromere protein I
chr8_+_72743426 9.82 ENSRNOT00000072573
ribosomal protein S27-like
chr7_-_18793289 9.82 ENSRNOT00000036375

chr6_-_51297712 9.75 ENSRNOT00000082985
protein kinase cAMP-dependent type 2 regulatory subunit beta
chrX_-_138435391 9.65 ENSRNOT00000043258
muscleblind-like splicing regulator 3
chr4_-_165192647 9.59 ENSRNOT00000086461
killer cell lectin-like receptor, subfamily A, member 5
chr1_+_219403970 9.51 ENSRNOT00000029607
protein tyrosine phosphatase, receptor type, C-associated protein
chr10_-_19574094 9.50 ENSRNOT00000059810
dedicator of cytokinesis 2
chrX_-_38026774 9.43 ENSRNOT00000074898
SH3 domain-containing kinase-binding protein 1
chr4_+_78378144 9.36 ENSRNOT00000059156
GTPase, IMAP family member 5
chr15_+_32828165 9.23 ENSRNOT00000060253

chr10_-_90312386 9.06 ENSRNOT00000028445
solute carrier family 4 member 1
chr4_+_78378313 9.06 ENSRNOT00000083891
GTPase, IMAP family member 5
chr8_+_132869712 8.92 ENSRNOT00000008294
C-X-C motif chemokine receptor 6
chr9_-_53118613 8.89 ENSRNOT00000065581
ORMDL sphingolipid biosynthesis regulator 1
chr2_+_193866951 8.72 ENSRNOT00000013393
S100 calcium binding protein A11
chr15_+_5772679 8.71 ENSRNOT00000043553

chr1_+_64074231 8.67 ENSRNOT00000077327
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3-like
chr3_-_148057523 8.49 ENSRNOT00000055408
defensin beta 24
chr1_+_63759638 8.32 ENSRNOT00000080799
ENSRNOT00000087669
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3A
chr4_+_96562725 8.32 ENSRNOT00000009094
neuron-derived neurotrophic factor
chr2_+_122368265 8.24 ENSRNOT00000078321
ATPase phospholipid transporting 11B (putative)
chr9_+_12740885 8.14 ENSRNOT00000015210
raftlin lipid raft linker 1
chr4_-_103569159 8.00 ENSRNOT00000084036

chr20_+_3146856 8.00 ENSRNOT00000050159
RT1 class Ib, locus N2
chr10_-_70871066 7.95 ENSRNOT00000015139
C-C motif chemokine ligand 3
chr2_-_105047984 7.73 ENSRNOT00000014970
carboxypeptidase A3
chr1_-_197821936 7.69 ENSRNOT00000055027
CD19 molecule
chr8_-_49280901 7.61 ENSRNOT00000021390
CD3g molecule
chr7_+_3173287 7.58 ENSRNOT00000092037
PYM homolog 1, exon junction complex associated factor
chr19_-_29400355 7.57 ENSRNOT00000072100
mitochondrial brown fat uncoupling protein 1-like
chr17_-_86657473 7.20 ENSRNOT00000078827

chr20_+_6211420 7.17 ENSRNOT00000000624
potassium channel tetramerization domain containing 20
chr15_-_100348760 7.15 ENSRNOT00000085607

chr17_-_43815183 7.03 ENSRNOT00000073188
histone cluster 1, H2ai-like1
chr1_-_61872975 7.02 ENSRNOT00000078809

chrX_+_77143892 6.97 ENSRNOT00000085227
ATPase copper transporting alpha
chr1_+_227592635 6.90 ENSRNOT00000072135
membrane-spanning 4-domains, subfamily A, member 4A
chr11_-_60819249 6.81 ENSRNOT00000043917
ENSRNOT00000042447
CD200 receptor 1-like
chr17_-_44643362 6.66 ENSRNOT00000091041
zinc finger protein 184
chr11_-_73678984 6.64 ENSRNOT00000002355
family with sequence similarity 43, member A
chr4_-_164049599 6.61 ENSRNOT00000078267

chr3_-_91217491 6.53 ENSRNOT00000006115
recombination activating 1
chr5_+_173447784 6.51 ENSRNOT00000027251
TNF receptor superfamily member 4
chr10_-_59112788 6.30 ENSRNOT00000041886
SPNS sphingolipid transporter 3
chr1_-_101123402 6.27 ENSRNOT00000027976

chr8_-_22929294 6.23 ENSRNOT00000015609
RAB3D, member RAS oncogene family
chr6_-_143131118 6.22 ENSRNOT00000074930

chr1_+_88885937 6.08 ENSRNOT00000029719
NFKB inhibitor delta
chr4_+_103524324 6.07 ENSRNOT00000087659

chr14_-_44225713 6.05 ENSRNOT00000049161
similar to ribosomal protein L14
chr3_+_20641664 6.04 ENSRNOT00000044699

chr14_+_86751157 5.96 ENSRNOT00000067997
60S ribosomal protein L13-like
chr7_-_54778848 5.91 ENSRNOT00000005399
GLI pathogenesis-related 1
chr4_-_164536556 5.84 ENSRNOT00000087796
Ly49 inhibitory receptor 2
chr3_+_19772056 5.84 ENSRNOT00000044455

chr9_+_112360419 5.76 ENSRNOT00000086682
mannosidase, alpha, class 2A, member 1
chr1_+_64740487 5.69 ENSRNOT00000081213
zinc finger protein 679-like
chr3_+_20303979 5.67 ENSRNOT00000058331

chr8_-_48634797 5.67 ENSRNOT00000012868
histone H4 transcription factor
chr14_-_18853315 5.65 ENSRNOT00000003794
pro-platelet basic protein
chr16_-_75481115 5.61 ENSRNOT00000035128
defensin alpha 7
chr10_+_73868943 5.57 ENSRNOT00000081012
tubulin, delta 1
chr14_+_81043454 5.51 ENSRNOT00000043609

chr15_+_32809069 5.49 ENSRNOT00000070848

chr1_+_98398660 5.43 ENSRNOT00000047473
CD33 molecule
chr4_+_102290338 5.42 ENSRNOT00000011067

chr13_+_27312498 5.40 ENSRNOT00000003466
serpin family B member 7
chr12_+_19714324 5.37 ENSRNOT00000072303
similar to cell surface receptor FDFACT
chr3_-_145810834 5.36 ENSRNOT00000075429
zinc finger protein 120-like
chr10_-_56530842 5.34 ENSRNOT00000077451

chr1_+_199555722 5.34 ENSRNOT00000054983
integrin subunit alpha X
chr14_-_86117578 5.33 ENSRNOT00000019288
DNA polymerase delta 2, accessory subunit
chr1_-_73619356 5.27 ENSRNOT00000074352
leukocyte immunoglobulin like receptor B3
chrX_-_105390580 5.27 ENSRNOT00000077547
Bruton tyrosine kinase
chr6_-_140572023 5.27 ENSRNOT00000072338

chr15_-_34612432 5.24 ENSRNOT00000090206
mast cell protease 1-like 1
chrX_-_76708878 5.21 ENSRNOT00000045534
ATRX, chromatin remodeler
chr10_-_112565146 5.20 ENSRNOT00000056238
ribosomal protein L5-like 1
chr4_-_81241152 5.19 ENSRNOT00000015325
ENSRNOT00000015152
heterogeneous nuclear ribonucleoprotein A2/B1
chr6_-_140102325 5.18 ENSRNOT00000072238

chr7_+_60316045 5.14 ENSRNOT00000064594
lysozyme C type 2
chr7_+_72599479 5.12 ENSRNOT00000018963

chrX_-_153491837 5.12 ENSRNOT00000089027
eukaryotic translation elongation factor 1 alpha 1-like
chr16_+_90325304 5.12 ENSRNOT00000057310
solute carrier family 10 member 2
chr10_-_70337532 5.09 ENSRNOT00000055963
schlafen family member 13
chr1_+_225163391 5.09 ENSRNOT00000027305
eukaryotic translation elongation factor 1 gamma
chr2_+_38230757 4.96 ENSRNOT00000048598
similar to 60S ribosomal protein L23a
chr20_+_3990820 4.94 ENSRNOT00000000528
proteasome subunit beta 8
chr10_-_4910305 4.91 ENSRNOT00000033122
RecQ mediated genome instability 2
chr16_-_25192675 4.88 ENSRNOT00000032289
membrane associated ring-CH-type finger 1
chr1_-_98493978 4.87 ENSRNOT00000023942
natural killer cell granule protein 7
chrX_+_120901495 4.86 ENSRNOT00000040742
WD repeat domain 44
chr5_+_144927759 4.81 ENSRNOT00000051387

chr9_-_54351339 4.80 ENSRNOT00000080522
signal transducer and activator of transcription 1
chr3_-_112985318 4.79 ENSRNOT00000015556
erythrocyte membrane protein band 4.2
chr12_+_25119355 4.78 ENSRNOT00000034629
linker for activation of T cells family, member 2
chr13_-_79899479 4.78 ENSRNOT00000035815
similar to hypothetical protein
chr1_-_47502952 4.74 ENSRNOT00000025580
T-cell activation RhoGTPase activating protein
chr3_+_19274273 4.74 ENSRNOT00000040102

chrX_+_35869538 4.73 ENSRNOT00000058947
protein phosphatase with EF-hand domain 1
chr1_-_136073483 4.72 ENSRNOT00000043854
ENSRNOT00000082564
ENSRNOT00000076340
solute carrier organic anion transporter family, member 3a1
chr6_+_26566494 4.69 ENSRNOT00000079292
general transcription factor IIIC subunit 2
chr4_+_102876038 4.68 ENSRNOT00000085205

chr18_-_61788859 4.66 ENSRNOT00000034075
ENSRNOT00000034069
collagen and calcium binding EGF domains 1
chr10_+_107469377 4.66 ENSRNOT00000087404
C1q and tumor necrosis factor related protein 1
chr1_+_63964155 4.63 ENSRNOT00000078512

chr3_+_19045214 4.62 ENSRNOT00000070878

chr3_-_171286413 4.60 ENSRNOT00000008365
ENSRNOT00000081036
Z-DNA binding protein 1
chr4_-_102124609 4.58 ENSRNOT00000048263

chr20_+_32717564 4.52 ENSRNOT00000030642
regulatory factor X, 6
chr2_+_143656793 4.51 ENSRNOT00000084527
ENSRNOT00000017453
periostin
chr16_-_71237118 4.46 ENSRNOT00000066974
nuclear receptor binding SET domain protein 3
chrX_-_104814145 4.43 ENSRNOT00000004909
synaptotagmin-like 4
chr2_+_87418517 4.41 ENSRNOT00000048046
tyrosine-protein phosphatase non-receptor type substrate 1-like
chrX_-_154918095 4.38 ENSRNOT00000085224
elongation factor 1-alpha 1-like
chr1_+_265761738 4.37 ENSRNOT00000024898
Hermansky-Pudlak syndrome 6
chr9_-_81586116 4.36 ENSRNOT00000089952
transmembrane BAX inhibitor motif containing 1
chr4_-_78342863 4.32 ENSRNOT00000049038
GTPase, IMAP family member 6
chr14_+_110676090 4.30 ENSRNOT00000029513
Fanconi anemia, complementation group L
chr1_-_221321459 4.22 ENSRNOT00000028406
ENSRNOT00000084800
DNA polymerase alpha 2, accessory subunit
chr10_+_95770154 4.22 ENSRNOT00000030300
helicase with zinc finger
chr4_-_163227242 4.21 ENSRNOT00000091552
ENSRNOT00000077793
C-type lectin domain family 7, member A
chrX_-_115496045 4.19 ENSRNOT00000051134
ribosomal protein S26-like
chr2_+_76923591 4.17 ENSRNOT00000042759
signal-regulatory protein alpha-like
chr8_+_2604962 4.15 ENSRNOT00000009993
caspase 1
chrX_+_15378789 4.15 ENSRNOT00000029272
GATA binding protein 1
chr10_+_17261541 4.14 ENSRNOT00000005478
SH3 and PX domains 2B
chr1_-_63684189 4.13 ENSRNOT00000085651
leukocyte immunoglobulin-like receptor, subfamily C, member 2
chr1_-_266142538 4.12 ENSRNOT00000026792
ARP1 actin-related protein 1 homolog A, centractin alpha
chr9_-_81586469 4.11 ENSRNOT00000019848
transmembrane BAX inhibitor motif containing 1
chr3_+_111826297 4.09 ENSRNOT00000081897
phospholipase A2 group IVB
chr16_-_83438561 4.07 ENSRNOT00000057461
collagen type IV alpha 2 chain
chr2_-_149444548 4.05 ENSRNOT00000018600
purinergic receptor P2Y12
chr2_+_196594303 4.05 ENSRNOT00000064442
ENSRNOT00000044738
aryl hydrocarbon receptor nuclear translocator
chr10_-_19715832 4.03 ENSRNOT00000040278
similar to ribosomal protein S10
chr9_-_84894599 3.98 ENSRNOT00000018423
histone deacetylase 1-like
chr10_+_87759769 3.96 ENSRNOT00000017378
ENSRNOT00000046526
keratin associated protein 9-1
chr4_-_164357619 3.96 ENSRNOT00000078114
Ly49 inhibitory receptor 5
chr18_+_55666027 3.94 ENSRNOT00000045950
similar to CDNA sequence BC023105
chr15_+_42489377 3.94 ENSRNOT00000064306
PDZ binding kinase
chr6_+_139177200 3.94 ENSRNOT00000084131

chr10_+_84182118 3.92 ENSRNOT00000011027
homeo box B3
chr7_-_15852930 3.92 ENSRNOT00000009270
similar to zinc finger protein 101
chr7_+_74350479 3.92 ENSRNOT00000089034

chr1_+_219468675 3.88 ENSRNOT00000025342
cardiotrophin-like cytokine factor 1
chr6_+_34030620 3.88 ENSRNOT00000091651
lysosomal protein transmembrane 4 alpha
chr9_+_61738471 3.87 ENSRNOT00000090305

chr6_+_145546595 3.86 ENSRNOT00000007112
Rap guanine nucleotide exchange factor 5
chr19_-_39267928 3.86 ENSRNOT00000027686
transmembrane p24 trafficking protein 6
chr2_-_252505971 3.85 ENSRNOT00000021984
dnaj-like protein
chr10_-_63952726 3.83 ENSRNOT00000090461
double C2 domain beta
chr4_+_102147211 3.82 ENSRNOT00000083239

chr10_+_104932616 3.81 ENSRNOT00000075706
similar to leukocyte mono-Ig-like receptor2
chr13_+_49005405 3.76 ENSRNOT00000092560
ENSRNOT00000076457
LEM domain containing 1
chr1_+_199495298 3.75 ENSRNOT00000086003
ENSRNOT00000026748
integrin subunit alpha D
chr14_-_25585222 3.73 ENSRNOT00000042106
similar to 60S ribosomal protein L9
chr14_-_21299068 3.71 ENSRNOT00000065778
amelotin
chr1_+_81474553 3.71 ENSRNOT00000083493
pleckstrin homology-like domain, family B, member 3
chr2_+_186685104 3.70 ENSRNOT00000057022
Cd5 molecule-like
chr5_-_59638385 3.70 ENSRNOT00000060203
ENSRNOT00000077367
ring finger protein 38
chr10_+_59725398 3.66 ENSRNOT00000026156
purinergic receptor P2X 5
chr19_+_52664322 3.62 ENSRNOT00000082754
cysteine-rich secretory protein LCCL domain containing 2
chr5_-_138239306 3.61 ENSRNOT00000039305
erythroblast membrane-associated protein
chr4_-_163570803 3.61 ENSRNOT00000082002
ENSRNOT00000078642
killer cell lectin-like receptor family I member 2
chr4_+_7662019 3.60 ENSRNOT00000014023
family with sequence similarity 126, member A
chr14_+_19319299 3.59 ENSRNOT00000086542
ankyrin repeat domain 17
chr7_-_141307233 3.56 ENSRNOT00000071885
Rac GTPase-activating protein 1
chr14_-_82347679 3.56 ENSRNOT00000032972
transforming, acidic coiled-coil containing protein 3
chr16_+_73584521 3.54 ENSRNOT00000024301
GINS complex subunit 4
chr4_-_163423628 3.54 ENSRNOT00000079526
killer cell lectin-like receptor subfamily C, member 3
chr2_-_165591110 3.54 ENSRNOT00000091140
intraflagellar transport 80
chr6_-_138536321 3.53 ENSRNOT00000077743

chr12_-_20276121 3.51 ENSRNOT00000065873
similar to paired immunoglobin-like type 2 receptor beta
chr4_+_93888502 3.49 ENSRNOT00000090783

chr3_+_91191837 3.49 ENSRNOT00000006097
recombination activating 2
chr8_+_103938520 3.49 ENSRNOT00000067835
glycerol kinase 5 (putative)
chrX_-_76924362 3.48 ENSRNOT00000078997
ATRX, chromatin remodeler
chr5_-_161875362 3.48 ENSRNOT00000078237
PR/SET domain 2
chr9_-_92405117 3.48 ENSRNOT00000079452
thyroid hormone receptor interactor 12

Network of associatons between targets according to the STRING database.

First level regulatory network of Olig2_Olig3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.4 GO:0001966 thigmotaxis(GO:0001966)
3.5 10.6 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
3.2 9.5 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
3.1 18.4 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
3.0 8.9 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
2.9 8.7 GO:1901580 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
2.8 8.5 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
2.7 10.7 GO:1901423 response to benzene(GO:1901423)
2.5 10.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
2.4 9.6 GO:0051542 negative regulation of iron ion transmembrane transport(GO:0034760) elastin biosynthetic process(GO:0051542) regulation of cytochrome-c oxidase activity(GO:1904959)
2.4 9.5 GO:0071226 cellular response to molecule of fungal origin(GO:0071226)
2.0 9.8 GO:0097332 response to antipsychotic drug(GO:0097332)
1.9 11.4 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
1.8 9.1 GO:0010037 response to carbon dioxide(GO:0010037)
1.6 9.5 GO:0033227 dsRNA transport(GO:0033227)
1.6 6.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
1.6 4.7 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) positive regulation of lymphangiogenesis(GO:1901492)
1.6 10.9 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
1.5 4.5 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
1.4 4.2 GO:0090579 regulation of primitive erythrocyte differentiation(GO:0010725) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
1.4 5.4 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
1.3 4.0 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
1.3 8.0 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
1.3 13.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
1.2 3.7 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
1.2 7.4 GO:0002051 osteoblast fate commitment(GO:0002051)
1.2 3.6 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
1.2 4.8 GO:0034240 negative regulation of macrophage fusion(GO:0034240)
1.2 3.6 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
1.2 4.7 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
1.1 9.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.1 3.3 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
1.1 3.2 GO:1904760 myofibroblast differentiation(GO:0036446) response to methyl methanesulfonate(GO:0072702) cellular response to methyl methanesulfonate(GO:0072703) regulation of myofibroblast differentiation(GO:1904760)
1.0 5.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
1.0 4.2 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
1.0 14.2 GO:0006968 cellular defense response(GO:0006968)
1.0 3.9 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
1.0 2.9 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
1.0 2.9 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.9 10.3 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.9 3.6 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.9 2.6 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.9 3.5 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.9 6.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.9 2.6 GO:0010847 regulation of chromatin assembly(GO:0010847) positive regulation of chromatin assembly or disassembly(GO:0045799)
0.9 7.7 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.8 3.1 GO:0046061 dATP catabolic process(GO:0046061)
0.8 3.0 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.8 2.3 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.7 2.2 GO:1903373 positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.7 2.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.7 3.5 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.7 3.3 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.7 2.0 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.6 3.2 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.6 11.6 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.6 2.5 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.6 2.5 GO:0032701 negative regulation of interleukin-18 production(GO:0032701)
0.6 2.4 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.6 1.8 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.6 1.2 GO:0045401 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.6 13.6 GO:0030574 collagen catabolic process(GO:0030574)
0.6 10.6 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.5 2.7 GO:0060623 pericentric heterochromatin assembly(GO:0031508) regulation of chromosome condensation(GO:0060623)
0.5 2.2 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.5 2.2 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.5 10.0 GO:0002517 T cell tolerance induction(GO:0002517)
0.5 5.8 GO:0006013 mannose metabolic process(GO:0006013)
0.5 1.5 GO:0097213 protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740) regulation of lysosomal membrane permeability(GO:0097213) positive regulation of lysosomal membrane permeability(GO:0097214) positive regulation of protein folding(GO:1903334)
0.5 4.7 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.5 2.8 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.4 1.8 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.4 6.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.4 4.6 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.4 3.7 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.4 1.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.4 1.6 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.4 3.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.4 2.8 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.4 2.8 GO:0006561 proline biosynthetic process(GO:0006561)
0.4 2.4 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.4 1.6 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.4 3.5 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.4 1.2 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.4 2.7 GO:0070782 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) phosphatidylserine exposure on apoptotic cell surface(GO:0070782) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.4 7.6 GO:1990845 adaptive thermogenesis(GO:1990845)
0.4 2.3 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.4 5.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.4 5.6 GO:0043312 neutrophil degranulation(GO:0043312)
0.4 1.1 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.4 2.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.3 1.4 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.3 9.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.3 4.0 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.3 3.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.3 5.3 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.3 3.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.3 1.7 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.3 1.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.3 11.3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.3 5.4 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.3 3.5 GO:0006228 UTP biosynthetic process(GO:0006228)
0.3 1.5 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.3 0.9 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.3 1.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.3 3.2 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.3 8.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.3 1.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.3 2.8 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.3 4.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.3 3.6 GO:0030953 astral microtubule organization(GO:0030953)
0.3 4.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.3 2.1 GO:0016584 nucleosome positioning(GO:0016584)
0.3 1.8 GO:0002579 positive regulation of antigen processing and presentation(GO:0002579)
0.3 0.8 GO:0002071 glandular epithelial cell maturation(GO:0002071) positive regulation of type B pancreatic cell development(GO:2000078)
0.3 1.6 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.3 2.1 GO:0015884 folic acid transport(GO:0015884)
0.3 1.8 GO:1902570 protein localization to nucleolus(GO:1902570)
0.3 0.5 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.2 10.7 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.2 4.7 GO:0015732 prostaglandin transport(GO:0015732)
0.2 2.3 GO:0070995 NADPH oxidation(GO:0070995)
0.2 1.8 GO:0015808 L-alanine transport(GO:0015808)
0.2 11.5 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.2 2.9 GO:0034063 stress granule assembly(GO:0034063)
0.2 8.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.2 1.6 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.2 3.9 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.2 14.1 GO:0006414 translational elongation(GO:0006414)
0.2 0.9 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 0.9 GO:0030210 heparin biosynthetic process(GO:0030210)
0.2 4.9 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 2.8 GO:0090161 Golgi ribbon formation(GO:0090161)
0.2 5.3 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.2 3.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 5.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 4.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.2 1.0 GO:0034227 tRNA thio-modification(GO:0034227)
0.2 0.6 GO:0030578 PML body organization(GO:0030578) cellular response to anoxia(GO:0071454)
0.2 2.2 GO:2000193 positive regulation of fatty acid transport(GO:2000193)
0.2 2.9 GO:0051451 myoblast migration(GO:0051451)
0.2 8.7 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.2 1.5 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.2 0.9 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 1.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2 1.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 4.5 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.2 2.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342) paranodal junction assembly(GO:0030913)
0.2 1.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.2 0.7 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.2 0.9 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.2 1.4 GO:0035635 exocyst assembly(GO:0001927) entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.2 5.1 GO:0008206 bile acid metabolic process(GO:0008206)
0.2 4.2 GO:0006270 DNA replication initiation(GO:0006270)
0.2 3.9 GO:0030488 tRNA methylation(GO:0030488)
0.2 2.7 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.2 5.1 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.2 0.5 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 1.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.2 3.5 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.2 3.7 GO:0070932 histone H3 deacetylation(GO:0070932)
0.2 1.4 GO:2000210 positive regulation of anoikis(GO:2000210)
0.2 6.1 GO:0060325 face morphogenesis(GO:0060325)
0.1 1.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.9 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 1.3 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 1.0 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 8.0 GO:0070228 regulation of lymphocyte apoptotic process(GO:0070228)
0.1 3.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 9.3 GO:0032418 lysosome localization(GO:0032418)
0.1 1.0 GO:0046851 negative regulation of bone resorption(GO:0045779) negative regulation of bone remodeling(GO:0046851)
0.1 0.3 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.1 1.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 4.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.7 GO:0035822 meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
0.1 1.6 GO:0048853 forebrain morphogenesis(GO:0048853)
0.1 3.9 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.1 1.6 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.1 1.9 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 5.8 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.6 GO:0060346 bone trabecula formation(GO:0060346)
0.1 1.9 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.1 4.5 GO:0019882 antigen processing and presentation(GO:0019882)
0.1 0.7 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.1 3.3 GO:0010165 response to X-ray(GO:0010165)
0.1 1.0 GO:0050957 equilibrioception(GO:0050957)
0.1 1.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.7 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.1 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 10.1 GO:0006334 nucleosome assembly(GO:0006334)
0.1 0.3 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 0.6 GO:0009624 response to nematode(GO:0009624)
0.1 1.8 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 0.7 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1 1.8 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 4.9 GO:0033045 regulation of sister chromatid segregation(GO:0033045)
0.1 1.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.5 GO:0001302 replicative cell aging(GO:0001302)
0.1 0.3 GO:0000393 generation of catalytic spliceosome for second transesterification step(GO:0000350) spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1 5.4 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 3.3 GO:0050798 activated T cell proliferation(GO:0050798)
0.1 0.4 GO:0051306 mitotic sister chromatid separation(GO:0051306)
0.1 2.2 GO:0045124 regulation of bone resorption(GO:0045124)
0.1 1.4 GO:0001967 suckling behavior(GO:0001967)
0.1 0.6 GO:0060723 regulation of spongiotrophoblast cell proliferation(GO:0060721) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.3 GO:0060685 regulation of prostatic bud formation(GO:0060685) negative regulation of prostatic bud formation(GO:0060686)
0.1 0.6 GO:0042045 S-adenosylmethionine cycle(GO:0033353) epithelial fluid transport(GO:0042045)
0.1 3.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 0.3 GO:0072720 response to dithiothreitol(GO:0072720)
0.1 1.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.5 GO:0042474 middle ear morphogenesis(GO:0042474)
0.1 1.9 GO:0007602 phototransduction(GO:0007602)
0.1 0.2 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.4 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.5 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.1 4.6 GO:0006513 protein monoubiquitination(GO:0006513)
0.1 9.6 GO:0008360 regulation of cell shape(GO:0008360)
0.1 0.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 1.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 1.9 GO:0007143 female meiotic division(GO:0007143)
0.1 2.9 GO:0021762 substantia nigra development(GO:0021762)
0.1 1.3 GO:0051983 regulation of chromosome segregation(GO:0051983)
0.1 0.9 GO:0007020 microtubule nucleation(GO:0007020)
0.1 0.3 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.1 0.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.7 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 0.6 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.1 0.8 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 3.0 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 0.8 GO:0019377 glycolipid catabolic process(GO:0019377)
0.1 2.5 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 1.2 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.7 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.6 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.9 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.0 2.2 GO:1990090 cellular response to nerve growth factor stimulus(GO:1990090)
0.0 0.1 GO:0060468 prevention of polyspermy(GO:0060468)
0.0 0.9 GO:0030728 ovulation(GO:0030728)
0.0 1.5 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.1 GO:0042350 GDP-L-fucose biosynthetic process(GO:0042350)
0.0 3.6 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.9 GO:1901099 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 1.5 GO:0032570 response to progesterone(GO:0032570)
0.0 1.5 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.0 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 1.5 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 1.8 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 1.0 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.9 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.8 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.8 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.4 GO:0031424 keratinization(GO:0031424)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.6 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.4 GO:0046037 GMP metabolic process(GO:0046037)
0.0 0.3 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.3 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.2 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.0 3.0 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.0 0.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.4 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.2 GO:0036303 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0 0.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0006298 mismatch repair(GO:0006298)
0.0 0.0 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.7 GO:1990707 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
2.2 8.9 GO:0035339 SPOTS complex(GO:0035339)
1.9 13.2 GO:0042825 TAP complex(GO:0042825)
1.3 3.9 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
1.3 3.9 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
1.2 10.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
1.2 3.5 GO:0000811 GINS complex(GO:0000811)
1.1 9.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
1.1 3.2 GO:0032301 MutSalpha complex(GO:0032301)
1.1 5.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
1.1 6.4 GO:1990111 spermatoproteasome complex(GO:1990111)
1.0 8.0 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
1.0 7.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.9 7.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.9 3.6 GO:0097149 centralspindlin complex(GO:0097149)
0.8 4.2 GO:0072558 IPAF inflammasome complex(GO:0072557) NLRP1 inflammasome complex(GO:0072558) AIM2 inflammasome complex(GO:0097169)
0.8 12.0 GO:0016580 Sin3 complex(GO:0016580)
0.8 6.3 GO:0097452 GAIT complex(GO:0097452)
0.8 2.3 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.7 4.7 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.7 5.3 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282) eukaryotic 48S preinitiation complex(GO:0033290)
0.6 9.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.6 1.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.5 4.1 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.5 5.6 GO:0002177 manchette(GO:0002177)
0.5 1.5 GO:1990836 lysosomal matrix(GO:1990836)
0.5 3.0 GO:0036157 outer dynein arm(GO:0036157) sperm cytoplasmic droplet(GO:0097598)
0.5 2.9 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.5 1.9 GO:0097196 Shu complex(GO:0097196)
0.4 11.4 GO:0001891 phagocytic cup(GO:0001891)
0.4 10.1 GO:0042629 mast cell granule(GO:0042629)
0.3 2.7 GO:0001740 Barr body(GO:0001740)
0.3 9.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.3 8.6 GO:0042588 zymogen granule(GO:0042588)
0.3 7.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.3 2.1 GO:0016589 NURF complex(GO:0016589)
0.3 9.1 GO:0008305 integrin complex(GO:0008305)
0.3 2.6 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.3 1.0 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.2 3.7 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.2 0.9 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.2 1.3 GO:0033010 paranodal junction(GO:0033010)
0.2 3.8 GO:0005682 U5 snRNP(GO:0005682)
0.2 3.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 4.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 16.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 1.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.2 2.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 4.5 GO:0005605 basal lamina(GO:0005605)
0.2 2.6 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.2 1.4 GO:0005688 U6 snRNP(GO:0005688)
0.2 1.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 11.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 3.3 GO:0031082 BLOC complex(GO:0031082)
0.1 6.6 GO:0031201 SNARE complex(GO:0031201)
0.1 44.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 0.8 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 1.0 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.9 GO:0042788 polysomal ribosome(GO:0042788)
0.1 1.2 GO:0061700 GATOR2 complex(GO:0061700)
0.1 21.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 3.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.4 GO:1902560 GMP reductase complex(GO:1902560)
0.1 1.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 5.4 GO:0002102 podosome(GO:0002102)
0.1 1.0 GO:0060091 kinocilium(GO:0060091)
0.1 6.2 GO:0015030 Cajal body(GO:0015030)
0.1 14.9 GO:0000776 kinetochore(GO:0000776)
0.1 5.2 GO:0016235 aggresome(GO:0016235)
0.1 5.1 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.6 GO:0071203 WASH complex(GO:0071203)
0.1 8.6 GO:0000786 nucleosome(GO:0000786)
0.1 1.0 GO:0034709 methylosome(GO:0034709)
0.1 1.1 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.7 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 2.9 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.7 GO:0032437 cuticular plate(GO:0032437)
0.1 1.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 3.2 GO:0016592 mediator complex(GO:0016592)
0.1 0.7 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 4.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.9 GO:0031045 dense core granule(GO:0031045)
0.1 1.4 GO:0000145 exocyst(GO:0000145)
0.1 28.0 GO:0000785 chromatin(GO:0000785)
0.1 1.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.6 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 4.4 GO:0000502 proteasome complex(GO:0000502)
0.1 1.4 GO:1990391 DNA repair complex(GO:1990391)
0.1 0.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 2.5 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 7.1 GO:0030139 endocytic vesicle(GO:0030139)
0.1 3.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 1.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 10.9 GO:0010008 endosome membrane(GO:0010008)
0.1 14.9 GO:0016607 nuclear speck(GO:0016607)
0.0 2.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 6.9 GO:0030018 Z disc(GO:0030018)
0.0 0.4 GO:0005833 hemoglobin complex(GO:0005833)
0.0 2.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 2.1 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 3.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 3.5 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 5.0 GO:0005813 centrosome(GO:0005813)
0.0 0.9 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0032153 actomyosin contractile ring(GO:0005826) cell division site(GO:0032153) cell division site part(GO:0032155)
0.0 0.4 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 4.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.1 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.7 GO:0042383 sarcolemma(GO:0042383)
0.0 2.9 GO:0030133 transport vesicle(GO:0030133)
0.0 0.1 GO:0000800 lateral element(GO:0000800)
0.0 2.5 GO:0005874 microtubule(GO:0005874)
0.0 0.1 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.7 GO:0016748 succinyltransferase activity(GO:0016748)
2.7 8.0 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
2.6 13.2 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
1.9 9.6 GO:0032767 copper-exporting ATPase activity(GO:0004008) copper-dependent protein binding(GO:0032767) copper-transporting ATPase activity(GO:0043682)
1.9 7.6 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
1.7 8.7 GO:0015616 DNA translocase activity(GO:0015616)
1.7 5.2 GO:0001069 regulatory region RNA binding(GO:0001069)
1.4 9.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
1.3 4.0 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
1.3 3.9 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
1.2 3.6 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
1.2 10.8 GO:0008494 translation activator activity(GO:0008494)
1.2 4.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
1.1 3.3 GO:0004566 beta-glucuronidase activity(GO:0004566)
1.1 8.9 GO:0019958 C-X-C chemokine binding(GO:0019958)
1.1 3.3 GO:0008506 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
1.1 3.2 GO:0032142 dinucleotide insertion or deletion binding(GO:0032139) single guanine insertion binding(GO:0032142)
1.0 6.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
1.0 3.1 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
1.0 11.4 GO:0032036 myosin heavy chain binding(GO:0032036)
1.0 2.9 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.9 1.8 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.9 9.5 GO:0042608 T cell receptor binding(GO:0042608)
0.9 5.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.8 6.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.7 2.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.7 2.9 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.7 14.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.6 3.9 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.6 4.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.6 1.3 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.6 1.9 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.6 4.0 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.6 5.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.6 7.3 GO:0003796 lysozyme activity(GO:0003796)
0.5 1.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5 3.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.5 5.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.5 1.5 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.5 2.9 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.5 4.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.5 8.7 GO:0044548 S100 protein binding(GO:0044548)
0.5 2.4 GO:0004974 leukotriene receptor activity(GO:0004974)
0.5 13.8 GO:0042287 MHC protein binding(GO:0042287)
0.5 4.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.5 2.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.4 5.8 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.4 2.2 GO:0001729 ceramide kinase activity(GO:0001729)
0.4 4.8 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.4 2.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.4 9.1 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.4 4.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.4 1.7 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.4 3.7 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.4 8.5 GO:0005123 death receptor binding(GO:0005123)
0.4 2.4 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.4 1.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.4 2.2 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.4 5.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.4 1.8 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.3 2.1 GO:0005499 vitamin D binding(GO:0005499)
0.3 12.3 GO:0042605 peptide antigen binding(GO:0042605)
0.3 2.4 GO:0035375 zymogen binding(GO:0035375)
0.3 9.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.3 1.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.3 1.2 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.3 3.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.3 3.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.3 2.6 GO:0043495 protein anchor(GO:0043495)
0.3 7.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.3 1.4 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.3 15.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3 2.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.3 1.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.2 3.2 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.2 6.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 4.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.2 0.9 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2 3.2 GO:0035497 cAMP response element binding(GO:0035497)
0.2 3.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 2.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 5.1 GO:0031489 myosin V binding(GO:0031489)
0.2 1.2 GO:0019767 IgE receptor activity(GO:0019767)
0.2 0.8 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 2.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 3.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.2 2.4 GO:0004697 protein kinase C activity(GO:0004697)
0.2 0.9 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 2.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 0.5 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 2.9 GO:0050811 GABA receptor binding(GO:0050811)
0.2 32.8 GO:0042393 histone binding(GO:0042393)
0.2 1.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 5.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 3.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 0.6 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 3.1 GO:0004950 chemokine receptor activity(GO:0004950)
0.1 2.2 GO:0043422 protein kinase B binding(GO:0043422)
0.1 1.0 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 11.1 GO:0005518 collagen binding(GO:0005518)
0.1 3.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 1.5 GO:0004383 adenylate cyclase activity(GO:0004016) guanylate cyclase activity(GO:0004383)
0.1 5.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 1.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.4 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 3.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.0 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 2.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 8.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 5.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 32.5 GO:0030246 carbohydrate binding(GO:0030246)
0.1 22.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 5.2 GO:0030145 manganese ion binding(GO:0030145)
0.1 1.6 GO:0070628 proteasome binding(GO:0070628)
0.1 27.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.3 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 1.7 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 0.9 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.9 GO:0008061 chitin binding(GO:0008061)
0.1 1.8 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.1 2.6 GO:0050699 WW domain binding(GO:0050699)
0.1 3.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 11.2 GO:0008201 heparin binding(GO:0008201)
0.1 2.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 6.7 GO:0001948 glycoprotein binding(GO:0001948)
0.1 3.4 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.1 0.7 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 31.0 GO:0005525 GTP binding(GO:0005525)
0.1 1.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 3.1 GO:0000049 tRNA binding(GO:0000049)
0.1 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.5 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.1 0.8 GO:0015925 galactosidase activity(GO:0015925)
0.1 0.9 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 3.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 2.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 2.7 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 3.3 GO:0043022 ribosome binding(GO:0043022)
0.1 1.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.5 GO:0071837 HMG box domain binding(GO:0071837)
0.1 2.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 2.6 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 0.8 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 3.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 7.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 12.5 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 7.2 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 2.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 2.0 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.2 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 1.9 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.8 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 2.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.9 GO:0005507 copper ion binding(GO:0005507)
0.0 1.9 GO:0044325 ion channel binding(GO:0044325)
0.0 1.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 17.7 GO:0003723 RNA binding(GO:0003723)
0.0 0.1 GO:0052813 insulin receptor substrate binding(GO:0043560) phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.2 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.5 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 1.2 GO:0016503 pheromone receptor activity(GO:0016503)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 10.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.5 2.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.3 4.8 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.3 10.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.3 13.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.3 10.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.3 3.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 14.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.2 3.2 PID ALK2 PATHWAY ALK2 signaling events
0.2 7.9 PID BARD1 PATHWAY BARD1 signaling events
0.2 2.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 5.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.2 16.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 6.0 PID AURORA A PATHWAY Aurora A signaling
0.2 2.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 3.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 8.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 2.8 PID ARF 3PATHWAY Arf1 pathway
0.1 6.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 3.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 9.5 PID CMYB PATHWAY C-MYB transcription factor network
0.1 4.7 PID ENDOTHELIN PATHWAY Endothelins
0.1 14.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 2.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 4.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 1.7 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 1.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 1.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 2.4 PID RHOA PATHWAY RhoA signaling pathway
0.1 8.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 2.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.0 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 3.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.9 PID INSULIN PATHWAY Insulin Pathway
0.0 8.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 5.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.6 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 7.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.6 5.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.6 10.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.6 21.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.5 9.6 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.5 11.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.5 13.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.5 5.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.4 22.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.4 9.2 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.4 4.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.4 9.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.3 4.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 2.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.3 9.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.3 3.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.3 14.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.3 4.6 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.3 12.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.3 3.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 5.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.2 5.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2 8.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 2.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 2.4 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.2 9.7 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.2 10.8 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.2 1.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 4.8 REACTOME KINESINS Genes involved in Kinesins
0.1 8.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 2.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.8 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 3.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 8.0 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.1 0.9 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 1.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.0 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 10.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 2.3 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 0.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.3 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 3.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 2.6 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 1.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 5.1 REACTOME TRANSLATION Genes involved in Translation
0.1 0.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 1.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 0.3 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 0.7 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 1.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.8 REACTOME GABA RECEPTOR ACTIVATION Genes involved in GABA receptor activation
0.0 5.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 2.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.6 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 3.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease