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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Nr3c2

Z-value: 0.75

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Transcription factors associated with Nr3c2

Gene Symbol Gene ID Gene Info
ENSRNOG00000034007 nuclear receptor subfamily 3, group C, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr3c2rn6_v1_chr19_-_34752695_347526950.396.9e-13Click!

Activity profile of Nr3c2 motif

Sorted Z-values of Nr3c2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_147303346 35.06 ENSRNOT00000009153
hippocalcin
chr2_-_198016898 29.53 ENSRNOT00000025523
carbonic anhydrase 14
chr1_+_27476375 29.43 ENSRNOT00000047224
ENSRNOT00000075427
sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2-like
chr9_+_73319710 24.60 ENSRNOT00000092485
microtubule-associated protein 2
chr7_-_138483612 23.62 ENSRNOT00000085620
solute carrier family 38, member 4
chr20_-_53777159 23.14 ENSRNOT00000073994

chr6_-_26624092 23.12 ENSRNOT00000008113
tripartite motif-containing 54
chr14_-_43143973 19.31 ENSRNOT00000003248
ubiquitin C-terminal hydrolase L1
chr8_-_55144087 18.76 ENSRNOT00000039045
DIX domain containing 1
chr1_+_191344979 17.39 ENSRNOT00000023773
heparan sulfate-glucosamine 3-sulfotransferase 2
chrX_+_62366453 13.61 ENSRNOT00000089828
aristaless related homeobox
chr4_-_159079003 13.39 ENSRNOT00000026691
potassium voltage-gated channel subfamily A member 5
chrX_+_72684329 10.57 ENSRNOT00000057644
DMRT-like family C1c1
chr15_+_52220578 10.50 ENSRNOT00000015104
leucine-rich repeat LGI family, member 3
chr14_-_78377825 9.15 ENSRNOT00000068104

chr11_-_57993548 8.93 ENSRNOT00000002957
nectin cell adhesion molecule 3
chr13_+_104816371 8.53 ENSRNOT00000086497

chr3_+_95614562 7.21 ENSRNOT00000079990

chr19_+_24655626 6.66 ENSRNOT00000086690

chr4_-_32392007 6.42 ENSRNOT00000014946
distal-less homeobox 5
chrX_+_153677811 6.41 ENSRNOT00000072808

chr2_+_166475070 6.23 ENSRNOT00000071111

chr1_+_91716383 6.19 ENSRNOT00000016919
solute carrier family 7 member 9
chr2_+_89254154 6.11 ENSRNOT00000073391

chr5_-_79899054 5.23 ENSRNOT00000074379

chr10_-_52483325 5.18 ENSRNOT00000083485

chr19_-_21970103 5.02 ENSRNOT00000074210

chr6_-_143230111 5.00 ENSRNOT00000081569

chr6_+_54438436 4.96 ENSRNOT00000091972

chr11_-_17286846 4.85 ENSRNOT00000080073

chr7_+_143707237 4.78 ENSRNOT00000074212
tensin 2
chr14_+_18231860 4.39 ENSRNOT00000003686
betacellulin
chr13_+_29839867 4.31 ENSRNOT00000090623

chr14_-_43855745 4.24 ENSRNOT00000083155

chr1_-_173393390 4.01 ENSRNOT00000050657
olfactory receptor 285
chr2_+_52152536 3.98 ENSRNOT00000072691

chr3_-_76012929 3.91 ENSRNOT00000085199

chr3_-_2938883 3.89 ENSRNOT00000084196
allergen Fel d 4-like
chr19_+_27603307 3.83 ENSRNOT00000074702

chr15_-_42271443 3.75 ENSRNOT00000085508

chr8_+_132441285 3.38 ENSRNOT00000087488
ENSRNOT00000068233
leucyl-tRNA synthetase 2
chrX_+_82710329 3.31 ENSRNOT00000074962

chr7_+_96195209 3.14 ENSRNOT00000073584

chr3_+_116072294 2.98 ENSRNOT00000071786

chr3_+_3236870 2.97 ENSRNOT00000065658
allergen Fel d 4-like
chr7_+_143754892 2.90 ENSRNOT00000085896
sterol O-acyltransferase 2
chr7_-_123287721 2.81 ENSRNOT00000009152
NHP2 non-histone chromosome protein 2-like 1-like
chr2_-_167607919 2.80 ENSRNOT00000089083

chr16_+_33373615 2.53 ENSRNOT00000079157

chr6_-_86161333 2.51 ENSRNOT00000072471

chr16_+_33373423 2.46 ENSRNOT00000091672

chr2_+_70490155 2.37 ENSRNOT00000078674

chr2_+_256609787 2.36 ENSRNOT00000047564
ENSRNOT00000088437
adhesion G protein-coupled receptor L4
chr20_+_3364814 2.12 ENSRNOT00000001077
hypothetical protein MGC:15854
chr18_-_15284077 2.11 ENSRNOT00000046326
LRRGT00165
chr3_-_2938663 1.65 ENSRNOT00000050294
allergen Fel d 4-like
chr5_-_162688935 1.60 ENSRNOT00000034394
arylacetamide deacetylase-like 4
chr2_+_149899538 1.48 ENSRNOT00000065365
similar to hypothetical protein C130079G13
chr4_-_160605107 1.42 ENSRNOT00000090725
tetraspanin 9
chr1_-_69016426 1.22 ENSRNOT00000093436

chrX_-_77529374 1.07 ENSRNOT00000078213
fibronectin type III domain containing 3C1
chr15_+_34270648 0.85 ENSRNOT00000026333
ring finger protein 31
chr20_-_2757489 0.81 ENSRNOT00000081833
butyrophilin-like 7
chr15_-_49467174 0.57 ENSRNOT00000019209
ADAM metallopeptidase domain 7
chr11_-_38274217 0.27 ENSRNOT00000002206
receptor-interacting serine-threonine kinase 4
chr3_+_75559775 0.25 ENSRNOT00000035844
preferentially expressed antigen in melanoma-like 6

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr3c2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
11.7 35.1 GO:0030824 negative regulation of cGMP metabolic process(GO:0030824)
2.7 18.8 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
2.3 13.6 GO:0021759 globus pallidus development(GO:0021759)
2.2 13.4 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
2.1 19.3 GO:0019896 axonal transport of mitochondrion(GO:0019896)
2.1 6.4 GO:0060166 olfactory pit development(GO:0060166)
1.5 6.2 GO:0015811 L-cystine transport(GO:0015811)
1.2 47.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
1.0 8.9 GO:1902414 protein localization to cell junction(GO:1902414)
0.7 2.1 GO:0032197 transposition, RNA-mediated(GO:0032197)
0.4 2.8 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.3 2.9 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.3 23.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.2 27.4 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.2 4.8 GO:0014850 response to muscle activity(GO:0014850)
0.2 3.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.8 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 4.4 GO:0045840 positive regulation of mitotic nuclear division(GO:0045840)
0.0 10.5 GO:0017157 regulation of exocytosis(GO:0017157)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.4 GO:0046691 intracellular canaliculus(GO:0046691)
2.9 35.1 GO:0044327 dendritic spine head(GO:0044327)
2.7 24.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.4 2.8 GO:0001651 dense fibrillar component(GO:0001651)
0.4 19.3 GO:1904115 axon cytoplasm(GO:1904115)
0.2 1.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 0.8 GO:0071797 LUBAC complex(GO:0071797)
0.2 23.1 GO:0005875 microtubule associated complex(GO:0005875)
0.1 8.9 GO:0044291 cell-cell contact zone(GO:0044291)
0.1 6.2 GO:0031526 brush border membrane(GO:0031526)
0.1 16.6 GO:0043679 axon terminus(GO:0043679)
0.1 10.5 GO:0008021 synaptic vesicle(GO:0008021)
0.0 2.9 GO:0005903 brush border(GO:0005903)
0.0 17.3 GO:0000139 Golgi membrane(GO:0000139)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 19.3 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
3.3 13.4 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
2.9 17.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
2.3 29.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
1.5 6.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
1.1 24.6 GO:0002162 dystroglycan binding(GO:0002162)
1.0 13.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.9 2.8 GO:0034512 box C/D snoRNA binding(GO:0034512)
0.6 18.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.3 6.4 GO:0071837 HMG box domain binding(GO:0071837)
0.2 3.4 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.2 23.6 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 2.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 4.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 23.1 GO:0008017 microtubule binding(GO:0008017)
0.1 32.9 GO:0003779 actin binding(GO:0003779)
0.0 2.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 8.9 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 1.5 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 19.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.4 24.6 PID LKB1 PATHWAY LKB1 signaling events
0.2 4.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 18.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 6.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 10.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 29.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.6 17.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.3 13.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 4.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.2 3.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation