Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Nr2f6

Z-value: 0.75

Motif logo

Transcription factors associated with Nr2f6

Gene Symbol Gene ID Gene Info
ENSRNOG00000016892 nuclear receptor subfamily 2, group F, member 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr2f6rn6_v1_chr16_-_19777414_19777414-0.108.1e-02Click!

Activity profile of Nr2f6 motif

Sorted Z-values of Nr2f6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_219144205 24.96 ENSRNOT00000083942
unc-93 homolog B1 (C. elegans)
chr1_+_215628785 21.13 ENSRNOT00000054864
lymphocyte-specific protein 1
chr1_+_100224401 21.07 ENSRNOT00000025846
Friend virus susceptibility 1
chrX_+_45420596 18.70 ENSRNOT00000051897
steroid sulfatase (microsomal), isozyme S
chr2_-_225107283 18.42 ENSRNOT00000055711
solute carrier family 44, member 3
chr10_-_55965216 17.60 ENSRNOT00000057058
chromodomain helicase DNA binding protein 3
chr1_-_7480825 17.59 ENSRNOT00000048754
phosphatase and actin regulator 2
chr20_+_3351303 15.95 ENSRNOT00000080419
ENSRNOT00000001065
ENSRNOT00000086503
alpha tubulin acetyltransferase 1
chr7_+_11077411 15.87 ENSRNOT00000007117
sphingosine-1-phosphate receptor 4
chr1_+_226091774 15.71 ENSRNOT00000027693
fatty acid desaturase 3
chr5_+_137257287 15.24 ENSRNOT00000037160
ELOVL fatty acid elongase 1
chr18_-_16542165 14.88 ENSRNOT00000079381
solute carrier family 39 member 6
chr6_+_43001948 14.79 ENSRNOT00000007374
hippocalcin-like 1
chr1_+_85162452 14.36 ENSRNOT00000093347
p21 (RAC1) activated kinase 4
chr1_-_262014066 13.61 ENSRNOT00000087083
HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
chr1_-_101651668 12.61 ENSRNOT00000028519
fucosyltransferase 2
chr3_+_62648447 12.51 ENSRNOT00000002111
alkylglycerone phosphate synthase
chr3_+_176494768 12.43 ENSRNOT00000040270
collagen type XX alpha 1 chain
chr20_-_3374344 12.34 ENSRNOT00000082999
protein phosphatase 1, regulatory subunit 18
chr4_+_162437089 12.12 ENSRNOT00000038801
C-type lectin domain family 2 member D2
chr19_+_49637016 12.10 ENSRNOT00000016880
beta-carotene oxygenase 1
chr6_+_106496992 11.82 ENSRNOT00000086136
ENSRNOT00000058181
regulator of G-protein signaling 6
chr1_-_100231460 11.73 ENSRNOT00000032200
acid phosphatase, testicular
chr4_+_157659147 11.70 ENSRNOT00000048379
intermediate filament family orphan 1
chr7_+_12471824 11.31 ENSRNOT00000068197
strawberry notch homolog 2
chrX_+_156873849 11.24 ENSRNOT00000085410
Rho GTPase activating protein 4
chr9_+_81783349 11.17 ENSRNOT00000021548
CCR4-NOT transcription complex subunit 9
chr8_+_55603968 10.67 ENSRNOT00000066848
POU class 2 associating factor 1
chr7_-_124620703 10.36 ENSRNOT00000017727
signal peptide, CUB domain and EGF like domain containing 1
chr8_+_127171537 10.28 ENSRNOT00000078625
ENSRNOT00000051290
ENSRNOT00000087753
golgin A4
chr3_-_161322289 9.97 ENSRNOT00000022594
phospholipid transfer protein
chr1_-_206282575 9.95 ENSRNOT00000024974
ADAM metallopeptidase domain 12
chr17_+_23661429 9.86 ENSRNOT00000046523
phosphatase and actin regulator 1
chr6_-_26051229 9.28 ENSRNOT00000005855
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr18_+_59096643 9.18 ENSRNOT00000025325
WD repeat domain 7
chr17_+_32516679 9.04 ENSRNOT00000032707
serine (or cysteine) peptidase inhibitor, clade B, member 9d
chr3_+_155297566 8.79 ENSRNOT00000021435
ENSRNOT00000084866
DEAH-box helicase 35
chr7_-_117605141 8.74 ENSRNOT00000035199
F-box and leucine-rich repeat protein 6
chrX_+_15610230 8.74 ENSRNOT00000012880
coiled-coil domain containing 120
chr13_+_89774764 8.67 ENSRNOT00000005619
Rho GTPase activating protein 30
chr4_+_150199627 8.55 ENSRNOT00000052259

chr5_+_137257637 8.36 ENSRNOT00000093001
ELOVL fatty acid elongase 1
chr5_-_102743417 8.26 ENSRNOT00000067389
basonuclin 2
chr2_+_86914989 8.18 ENSRNOT00000085164
ENSRNOT00000081966
zinc finger protein 457-like
chr5_+_173640780 8.03 ENSRNOT00000027476
PPARGC1 and ESRR induced regulator, muscle 1
chr14_+_85230648 7.88 ENSRNOT00000089866
adaptor-related protein complex 1, beta 1 subunit
chr8_+_99880073 7.88 ENSRNOT00000010765
phospholipid scramblase 4
chr12_-_24537313 7.81 ENSRNOT00000001975
bromodomain adjacent to zinc finger domain, 1B
chr6_-_128690741 7.80 ENSRNOT00000035826
spectrin repeat containing, nuclear envelope family member 3
chr5_-_137238354 7.79 ENSRNOT00000039235
seizure threshold 2 homolog (mouse)
chr1_-_144601327 7.66 ENSRNOT00000029244
ENSRNOT00000078144
stabilizer of axonemal microtubules 2
chr1_+_85192174 7.64 ENSRNOT00000026966
p21 (RAC1) activated kinase 4
chr6_+_44230985 7.57 ENSRNOT00000005858
kinase D-interacting substrate 220
chr1_-_163814364 7.53 ENSRNOT00000067026
similar to ribosomal protein L27
chr18_-_68983619 7.51 ENSRNOT00000014670
similar to chromosome 18 open reading frame 54
chr6_+_10348308 7.48 ENSRNOT00000034991
endothelial PAS domain protein 1
chr4_+_162292305 7.44 ENSRNOT00000010098
C-type lectin domain family 2, member D
chr12_-_18526250 7.43 ENSRNOT00000001791
acetylserotonin O-methyltransferase
chr4_+_14109864 7.37 ENSRNOT00000076349
similar to fatty acid translocase/CD36
chr17_+_42302540 7.36 ENSRNOT00000025389
geminin, DNA replication inhibitor
chr14_+_46001849 7.31 ENSRNOT00000076611
RELT-like 1
chr3_+_161272385 7.23 ENSRNOT00000021052
zinc finger, SWIM-type containing 3
chr17_+_9595761 7.20 ENSRNOT00000089990
family with sequence similarity 193, member B
chr17_+_55065621 7.05 ENSRNOT00000086342
zinc finger protein 438
chr7_-_127081704 7.04 ENSRNOT00000055893
uncharacterized LOC108351584
chr1_-_262013619 6.83 ENSRNOT00000021278
HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
chr7_+_35070284 6.51 ENSRNOT00000009578
nuclear receptor subfamily 2, group C, member 1
chr5_-_171710312 6.41 ENSRNOT00000076044
ENSRNOT00000071280
ENSRNOT00000072059
ENSRNOT00000077015
PR/SET domain 16
chr14_+_1463359 6.38 ENSRNOT00000070834
colony stimulating factor 2 receptor alpha subunit
chr15_-_14510828 6.16 ENSRNOT00000039347
sentan, cilia apical structure protein
chr6_+_123361864 6.08 ENSRNOT00000057577

chr4_+_117215064 6.07 ENSRNOT00000020909
SMYD family member 5
chr2_+_40554146 5.88 ENSRNOT00000015138
phosphodiesterase 4D
chr2_+_3662763 5.86 ENSRNOT00000017828
multiple C2 and transmembrane domain containing 1
chr1_+_89491654 5.78 ENSRNOT00000028632
leucine-rich repeat LGI family, member 4
chr7_-_62162453 5.76 ENSRNOT00000010720
cullin-associated and neddylation-dissociated 1
chr10_-_90312386 5.73 ENSRNOT00000028445
solute carrier family 4 member 1
chr7_-_34485034 5.69 ENSRNOT00000007351
small nuclear ribonucleoprotein polypeptide F
chr11_-_70211701 5.58 ENSRNOT00000076114
mucin 13, cell surface associated
chr8_+_61671513 5.55 ENSRNOT00000091128
protein tyrosine phosphatase, non-receptor type 9
chr20_-_29738506 5.54 ENSRNOT00000000697
carbohydrate sulfotransferase 3
chr1_+_226573105 5.51 ENSRNOT00000028074
cleavage and polyadenylation specific factor 7
chr5_+_129257429 5.49 ENSRNOT00000072396
tetratricopeptide repeat domain 39A
chr13_-_90589466 5.35 ENSRNOT00000070812
phosphoprotein enriched in astrocytes 15
chr1_+_144601410 5.34 ENSRNOT00000047408
elongation factor like GTPase 1
chr20_+_4530342 5.30 ENSRNOT00000076352
ENSRNOT00000000478
ENSRNOT00000075925
negative elongation factor complex member E
chr7_+_118490345 5.28 ENSRNOT00000046227
zinc finger protein 7-like
chr14_+_84465515 5.25 ENSRNOT00000035591
oncostatin M
chr14_+_1462358 5.23 ENSRNOT00000077243
colony stimulating factor 2 receptor alpha subunit
chr20_-_12938891 5.20 ENSRNOT00000017141
similar to Protein C21orf58
chr17_-_87826421 5.16 ENSRNOT00000068156
Rho GTPase activating protein 21
chr15_-_45947030 5.14 ENSRNOT00000035888
integrator complex subunit 6
chr1_+_79982639 5.03 ENSRNOT00000071916
dystrophia myotonica, WD repeat containing
chr7_-_12777901 4.93 ENSRNOT00000017245
transmembrane protein 259
chr7_+_127081978 4.90 ENSRNOT00000022945
TBC1 domain family, member 22a
chr1_-_80864846 4.80 ENSRNOT00000074412
immunoglobulin superfamily, member 23
chr10_+_43538160 4.76 ENSRNOT00000089217
CCR4-NOT transcription complex, subunit 8
chr1_+_225129097 4.74 ENSRNOT00000026938
echinoderm microtubule associated protein like 3
chr6_+_26537707 4.72 ENSRNOT00000050102
zinc finger protein 513
chr6_+_123034304 4.50 ENSRNOT00000078938
candidate plasticity gene 1
chr1_-_80630038 4.49 ENSRNOT00000025281
translocase of outer mitochondrial membrane 40
chr7_+_35069814 4.47 ENSRNOT00000089228
nuclear receptor subfamily 2, group C, member 1
chr13_-_48284408 4.45 ENSRNOT00000085967
SLIT-ROBO Rho GTPase activating protein 2
chr2_-_196304169 4.43 ENSRNOT00000028639
sodium channel modifier 1
chr1_-_8878136 4.41 ENSRNOT00000064836
ENSRNOT00000075850
vesicle trafficking 1
chr3_-_3691972 4.38 ENSRNOT00000061735
quiescin sulfhydryl oxidase 2
chr9_-_83253458 4.36 ENSRNOT00000041689
Eph receptor A4
chr15_-_43733182 4.31 ENSRNOT00000015318
protein phosphatase 2, regulatory subunit B, alpha
chr18_-_410098 4.26 ENSRNOT00000084138
cx9C motif-containing protein 4-like
chr19_-_37675077 4.23 ENSRNOT00000031033
enkurin domain containing 1
chr1_-_224986291 4.06 ENSRNOT00000026284
TATA-box binding protein associated factor 6 like
chr20_-_5533600 3.98 ENSRNOT00000072319
cutA divalent cation tolerance homolog
chr12_+_6403940 3.82 ENSRNOT00000083484
beta 3-glucosyltransferase
chr12_+_51937175 3.65 ENSRNOT00000056780
pseudouridylate synthase 1
chr9_+_42620006 3.63 ENSRNOT00000019966
heparan sulfate 6-O-sulfotransferase 1
chr2_-_80293181 3.52 ENSRNOT00000016111
OTU deubiquitinase with linear linkage specificity
chr2_+_196304492 3.52 ENSRNOT00000028640
LysM domain containing 1
chr3_+_154507035 3.45 ENSRNOT00000017265
regulation of nuclear pre-mRNA domain containing 1B
chr1_+_265904566 3.42 ENSRNOT00000086041
ENSRNOT00000036156
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr7_-_117688187 3.34 ENSRNOT00000019707
VPS28, ESCRT-I subunit
chr1_-_22269831 3.18 ENSRNOT00000081804
syntaxin 7
chr10_+_3227160 3.18 ENSRNOT00000088075
N-terminal asparagine amidase
chr13_-_44345735 3.13 ENSRNOT00000005006
transmembrane protein 163
chr9_+_69953440 3.09 ENSRNOT00000034740
eukaryotic translation elongation factor 1 beta 2
chr20_+_11168298 2.99 ENSRNOT00000032240
trafficking protein particle complex 10
chr2_+_44096061 2.93 ENSRNOT00000018438
ankyrin repeat domain 55
chr5_-_159577134 2.85 ENSRNOT00000011114
ciliary rootlet coiled-coil, rootletin
chr18_+_68983545 2.84 ENSRNOT00000085317
StAR-related lipid transfer domain containing 6
chr2_+_189582991 2.78 ENSRNOT00000022627
RAB13, member RAS oncogene family
chr7_-_14054639 2.72 ENSRNOT00000039852
ilvB acetolactate synthase like
chr9_+_79659251 2.69 ENSRNOT00000021656
X-ray repair cross complementing 5
chr20_-_5533448 2.69 ENSRNOT00000000568
cutA divalent cation tolerance homolog
chr13_-_89745835 2.61 ENSRNOT00000005352
kelch domain containing 9
chr3_+_151691515 2.60 ENSRNOT00000052236

chr4_-_6449949 2.44 ENSRNOT00000062026
polypeptide N-acetylgalactosaminyltransferase-like 5
chr5_-_24320786 2.37 ENSRNOT00000061569
NADH:ubiquinone oxidoreductase complex assembly factor 6
chr13_+_110511668 2.34 ENSRNOT00000006235
NIMA-related kinase 2
chr3_+_141068023 2.32 ENSRNOT00000036527
kizuna centrosomal protein
chr1_+_47942800 2.30 ENSRNOT00000079312
Wilms tumor 1 associated protein
chr10_+_89352835 2.24 ENSRNOT00000028060
ribosomal protein L27
chr8_+_117246376 2.18 ENSRNOT00000074493
coiled-coil domain containing 71
chr3_+_140024043 2.13 ENSRNOT00000086409
Ras and Rab interactor 2
chr13_-_73622211 2.07 ENSRNOT00000005235
centrosomal protein 350
chr6_-_52401853 2.06 ENSRNOT00000075513
cadherin-related family member 3
chr2_+_239415046 1.93 ENSRNOT00000072196
CXXC finger protein 4
chr1_-_226049929 1.90 ENSRNOT00000007320
bestrophin 1
chr10_-_12916784 1.83 ENSRNOT00000004589
zinc finger protein 13
chr4_-_113988246 1.76 ENSRNOT00000013128
WD repeat-containing protein 54
chr1_-_154170409 1.70 ENSRNOT00000089014
Hikeshi, heat shock protein nuclear import factor
chr12_-_6078411 1.64 ENSRNOT00000001197
relaxin/insulin-like family peptide receptor 2
chr19_-_55434252 1.64 ENSRNOT00000045052
poly(A)binding protein nuclear 1-like
chr1_+_185210922 1.62 ENSRNOT00000055120
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
chr17_-_49990982 1.60 ENSRNOT00000018458
ENSRNOT00000080628
M-phase specific PLK1 interacting protein
chr1_-_37957400 1.57 ENSRNOT00000085560
ENSRNOT00000079626
ENSRNOT00000071889
zinc finger protein 91-like
chr16_+_74810938 1.53 ENSRNOT00000058091
NIMA-related kinase 5
chr1_+_47942500 1.35 ENSRNOT00000025936
Wilms tumor 1 associated protein
chr7_-_123101851 1.32 ENSRNOT00000090984
ENSRNOT00000005837
PHD finger protein 5A
chr2_+_218834034 1.31 ENSRNOT00000018367
diphthamide biosynthesis 5
chr3_-_111037425 1.26 ENSRNOT00000085628
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr1_+_255185629 1.23 ENSRNOT00000083002
HECT domain E3 ubiquitin protein ligase 2
chr7_+_117951154 1.19 ENSRNOT00000060181
zinc finger protein 7
chr1_+_221612584 1.18 ENSRNOT00000090100
autophagy related 2A
chr12_-_37699616 1.08 ENSRNOT00000077803
similar to hypothetical protein FLJ38663
chr12_+_22026075 1.03 ENSRNOT00000029041
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1-like
chr3_-_160922341 0.91 ENSRNOT00000029206
TP53 target 5
chr1_-_89488223 0.85 ENSRNOT00000028624
FXYD domain-containing ion transport regulator 1
chr15_+_30525754 0.81 ENSRNOT00000086842

chr15_-_33218456 0.80 ENSRNOT00000017753
ajuba LIM protein
chr3_-_111037166 0.80 ENSRNOT00000017070
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr18_+_61261418 0.65 ENSRNOT00000064250
zinc finger protein 532
chr18_-_52017734 0.60 ENSRNOT00000081020
membrane associated ring-CH-type finger 3
chrX_-_128268285 0.58 ENSRNOT00000009755
ENSRNOT00000081880
THO complex 2
chr2_-_187706300 0.43 ENSRNOT00000092349
ENSRNOT00000026414
transmembrane protein 79
chr4_+_146455332 0.25 ENSRNOT00000009775
histamine receptor H 1
chr9_-_27511176 0.13 ENSRNOT00000036813
similar to Glutathione S-transferase A1 (GTH1) (HA subunit 1) (GST-epsilon) (GSTA1-1) (GST class-alpha)
chr10_-_65692016 0.13 ENSRNOT00000085074
ENSRNOT00000038690
solute carrier family 13 member 2
chr13_+_99005142 0.12 ENSRNOT00000004293
acyl-CoA binding domain containing 3
chr10_+_89635675 0.10 ENSRNOT00000028179
similar to SAP18
chr10_+_34975708 0.08 ENSRNOT00000064984
NHP2 ribonucleoprotein
chr11_+_74014983 0.08 ENSRNOT00000040884
glycoprotein V platelet
chr10_-_60942351 0.03 ENSRNOT00000026926
olfactory receptor 1509
chr1_-_189666440 0.00 ENSRNOT00000019167
defective in cullin neddylation 1 domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr2f6

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 15.9 GO:0071929 alpha-tubulin acetylation(GO:0071929)
3.8 11.3 GO:0071348 cellular response to interleukin-11(GO:0071348)
3.6 25.0 GO:2001184 toll-like receptor 7 signaling pathway(GO:0034154) positive regulation of interleukin-12 secretion(GO:2001184)
3.4 23.6 GO:0035338 fatty acid elongation, monounsaturated fatty acid(GO:0034625) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
3.3 10.0 GO:0042360 vitamin E metabolic process(GO:0042360)
2.9 11.6 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
2.6 20.4 GO:1903232 melanosome assembly(GO:1903232)
2.5 7.4 GO:0030186 melatonin metabolic process(GO:0030186)
2.5 7.4 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
2.2 11.2 GO:2000327 positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
2.1 12.5 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
2.0 5.9 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
1.9 5.8 GO:0010265 SCF complex assembly(GO:0010265)
1.8 11.0 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
1.5 7.5 GO:0048625 myoblast fate commitment(GO:0048625)
1.5 4.4 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
1.5 4.4 GO:2001106 fasciculation of motor neuron axon(GO:0097156) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
1.4 14.9 GO:0071578 zinc II ion transmembrane import(GO:0071578)
1.3 5.2 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
1.3 7.8 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
1.3 5.2 GO:0051684 maintenance of Golgi location(GO:0051684)
1.2 11.2 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
1.2 3.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
1.2 3.5 GO:1990108 protein linear deubiquitination(GO:1990108)
1.2 2.3 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
1.1 3.4 GO:0035964 COPI-coated vesicle budding(GO:0035964)
1.1 15.9 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
1.0 7.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
1.0 7.8 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.9 2.8 GO:1903566 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.9 2.8 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.9 6.4 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.9 3.7 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.9 12.6 GO:0036065 fucosylation(GO:0036065)
0.8 3.3 GO:0070086 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086)
0.8 1.6 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.8 3.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.8 5.3 GO:0042256 mature ribosome assembly(GO:0042256)
0.7 12.1 GO:0042574 retinal metabolic process(GO:0042574)
0.7 3.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.7 2.7 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.6 5.3 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.5 8.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.5 7.6 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.5 5.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.4 4.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.4 7.9 GO:0017121 phospholipid scrambling(GO:0017121)
0.4 3.7 GO:0080009 mRNA methylation(GO:0080009)
0.4 5.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.4 7.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.4 1.8 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.4 4.9 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.3 18.7 GO:0009268 response to pH(GO:0009268)
0.3 10.4 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.3 2.6 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.3 0.9 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.3 8.3 GO:0003416 endochondral bone growth(GO:0003416)
0.3 3.0 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 5.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.3 1.3 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.3 5.1 GO:0016180 snRNA processing(GO:0016180)
0.3 4.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 2.2 GO:1904044 response to aldosterone(GO:1904044)
0.2 1.9 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 5.8 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.2 5.7 GO:0015701 bicarbonate transport(GO:0015701)
0.2 5.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.2 9.3 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.1 0.4 GO:0042335 cuticle development(GO:0042335) cornification(GO:0070268)
0.1 0.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 17.6 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.1 2.1 GO:0034453 microtubule anchoring(GO:0034453)
0.1 13.6 GO:0060996 dendritic spine development(GO:0060996)
0.1 9.9 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1 0.3 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.1 1.2 GO:0044804 nucleophagy(GO:0044804)
0.1 11.7 GO:0042476 odontogenesis(GO:0042476)
0.1 1.6 GO:0001556 oocyte maturation(GO:0001556)
0.1 4.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 4.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 0.6 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.1 1.1 GO:0006415 translational termination(GO:0006415)
0.0 5.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 6.0 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 3.1 GO:0006414 translational elongation(GO:0006414)
0.0 18.2 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 2.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 4.9 GO:0051262 protein tetramerization(GO:0051262)
0.0 9.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.7 GO:0034605 cellular response to heat(GO:0034605)
0.0 3.3 GO:0016579 protein deubiquitination(GO:0016579)
0.0 1.5 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)
0.0 4.7 GO:0060041 retina development in camera-type eye(GO:0060041)
0.0 1.9 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 2.3 GO:0007051 spindle organization(GO:0007051)
0.0 2.4 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 20.4 GO:0031085 BLOC-3 complex(GO:0031085)
4.0 15.9 GO:0097427 microtubule bundle(GO:0097427)
2.3 25.0 GO:0032009 early phagosome(GO:0032009)
2.2 11.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
1.5 7.5 GO:0070552 BRISC complex(GO:0070552)
1.3 5.3 GO:0032021 NELF complex(GO:0032021)
1.1 7.8 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.0 3.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.9 5.7 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.8 14.9 GO:0031258 lamellipodium membrane(GO:0031258)
0.8 17.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.7 3.5 GO:0071797 LUBAC complex(GO:0071797)
0.7 2.7 GO:0043564 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) Ku70:Ku80 complex(GO:0043564)
0.6 3.7 GO:0036396 MIS complex(GO:0036396)
0.5 4.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.4 3.2 GO:0070820 tertiary granule(GO:0070820)
0.4 3.3 GO:0000813 ESCRT I complex(GO:0000813)
0.4 4.4 GO:0044327 dendritic spine head(GO:0044327)
0.3 4.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.3 4.1 GO:0030914 STAGA complex(GO:0030914)
0.3 5.1 GO:0032039 integrator complex(GO:0032039)
0.3 11.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 5.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.2 3.0 GO:0030008 TRAPP complex(GO:0030008)
0.2 7.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 7.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.2 2.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 2.8 GO:0035253 ciliary rootlet(GO:0035253)
0.2 12.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 22.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 4.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 5.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 3.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 5.7 GO:0016235 aggresome(GO:0016235)
0.1 11.0 GO:0016605 PML body(GO:0016605)
0.1 4.4 GO:0044295 axonal growth cone(GO:0044295)
0.1 4.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 9.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 5.7 GO:0014704 intercalated disc(GO:0014704)
0.1 3.4 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.1 10.1 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 10.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 1.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 3.4 GO:0005801 cis-Golgi network(GO:0005801)
0.1 4.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 11.2 GO:0030426 growth cone(GO:0030426)
0.1 0.6 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 3.6 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 9.2 GO:0008021 synaptic vesicle(GO:0008021)
0.1 2.8 GO:0034707 chloride channel complex(GO:0034707)
0.0 7.6 GO:0005770 late endosome(GO:0005770)
0.0 3.9 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 5.4 GO:0005882 intermediate filament(GO:0005882)
0.0 13.2 GO:0000139 Golgi membrane(GO:0000139)
0.0 2.3 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 12.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 2.0 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 4.1 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.6 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
3.9 11.6 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
2.4 23.6 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
2.3 15.9 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.8 25.0 GO:0035325 Toll-like receptor binding(GO:0035325)
1.6 15.9 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
1.5 4.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
1.3 18.7 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
1.0 22.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
1.0 29.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.9 5.5 GO:0034481 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) chondroitin sulfotransferase activity(GO:0034481)
0.9 4.4 GO:0042731 PH domain binding(GO:0042731)
0.6 7.5 GO:0050897 cobalt ion binding(GO:0050897)
0.6 14.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.6 7.9 GO:0042609 CD4 receptor binding(GO:0042609)
0.5 5.9 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.5 4.5 GO:0015266 protein channel activity(GO:0015266)
0.5 2.7 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.4 12.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.4 2.7 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.4 7.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.3 7.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.3 3.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.3 4.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.3 5.7 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.2 3.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 3.6 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.2 4.6 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 24.2 GO:0070035 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.2 5.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 9.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 1.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2 4.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 5.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 3.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 10.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 3.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 3.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 39.1 GO:0005096 GTPase activator activity(GO:0005096)
0.1 3.6 GO:0071949 FAD binding(GO:0071949)
0.1 18.3 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 0.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 2.8 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 20.4 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 7.9 GO:0030276 clathrin binding(GO:0030276)
0.1 6.7 GO:0005507 copper ion binding(GO:0005507)
0.1 6.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 4.3 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 1.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 9.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 9.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 13.9 GO:0019902 phosphatase binding(GO:0019902)
0.1 9.5 GO:0030165 PDZ domain binding(GO:0030165)
0.1 2.8 GO:0019894 kinesin binding(GO:0019894)
0.1 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 7.8 GO:0051015 actin filament binding(GO:0051015)
0.0 11.9 GO:0008017 microtubule binding(GO:0008017)
0.0 5.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 3.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 2.2 GO:0043022 ribosome binding(GO:0043022)
0.0 2.8 GO:0005254 chloride channel activity(GO:0005254)
0.0 5.2 GO:0008083 growth factor activity(GO:0008083)
0.0 6.2 GO:0051020 GTPase binding(GO:0051020)
0.0 8.2 GO:0030246 carbohydrate binding(GO:0030246)
0.0 6.3 GO:0016757 transferase activity, transferring glycosyl groups(GO:0016757)
0.0 6.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 9.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.6 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 1.3 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 15.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.8 21.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.7 21.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.5 33.2 SIG CHEMOTAXIS Genes related to chemotaxis
0.3 25.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.2 12.1 NABA COLLAGENS Genes encoding collagen proteins
0.2 4.4 PID IL3 PATHWAY IL3-mediated signaling events
0.2 3.4 PID ARF 3PATHWAY Arf1 pathway
0.2 7.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 4.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 13.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 4.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 5.3 PID P73PATHWAY p73 transcription factor network
0.1 1.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 1.6 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 2.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 10.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 3.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 25.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
1.9 18.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
1.3 23.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
1.0 22.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
1.0 7.9 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.8 14.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.7 18.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.6 3.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.5 5.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.4 7.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.4 7.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.4 5.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 7.6 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.3 5.5 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.3 10.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.3 4.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.3 2.7 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.2 5.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.2 11.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.2 4.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 5.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 3.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 4.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 27.7 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 3.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 9.9 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.1 2.3 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1 1.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 8.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 3.4 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.1 2.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 6.5 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 3.1 REACTOME TRANSLATION Genes involved in Translation
0.0 5.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.3 REACTOME MRNA SPLICING Genes involved in mRNA Splicing