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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Nr1i3

Z-value: 1.58

Motif logo

Transcription factors associated with Nr1i3

Gene Symbol Gene ID Gene Info
ENSRNOG00000003260 nuclear receptor subfamily 1, group I, member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr1i3rn6_v1_chr13_+_89586283_895863360.307.2e-08Click!

Activity profile of Nr1i3 motif

Sorted Z-values of Nr1i3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_78985990 97.32 ENSRNOT00000009248
alpha-1-microglobulin/bikunin precursor
chr8_+_116857684 74.29 ENSRNOT00000026711
macrophage stimulating 1
chr19_+_52077109 73.64 ENSRNOT00000020225
oxidative stress induced growth inhibitor 1
chr12_-_11733099 64.78 ENSRNOT00000051244
ENSRNOT00000087257
cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1
chr2_-_182038178 63.71 ENSRNOT00000040708
fibrinogen beta chain
chr8_+_50525091 62.54 ENSRNOT00000074357
apolipoprotein A1
chr12_-_22194287 62.44 ENSRNOT00000082895
ENSRNOT00000001905
transferrin receptor 2
chr17_+_22620721 58.62 ENSRNOT00000019478
androgen-dependent TFPI-regulating protein
chr20_-_12820466 58.58 ENSRNOT00000001699
formimidoyltransferase cyclodeaminase
chr14_+_22724399 57.85 ENSRNOT00000002724
UDP glucuronosyltransferase 2 family, polypeptide B10
chr8_-_85645718 57.84 ENSRNOT00000032185
glutathione S-transferase alpha 2
chr7_-_73270308 56.93 ENSRNOT00000007430
reactive intermediate imine deaminase A homolog
chr20_+_28989491 56.73 ENSRNOT00000074524
phospholipase A2, group XIIB
chr16_+_6970342 53.50 ENSRNOT00000061294
ENSRNOT00000048344
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr4_+_99063181 51.96 ENSRNOT00000008840
fatty acid binding protein 1
chr16_-_7007051 51.58 ENSRNOT00000023984
inter-alpha trypsin inhibitor, heavy chain 3
chr4_+_61850348 50.95 ENSRNOT00000013423
aldo-keto reductase family 1, member B7
chr13_+_89597138 50.18 ENSRNOT00000004662
apolipoprotein A2
chr19_+_52077501 48.75 ENSRNOT00000079240
oxidative stress induced growth inhibitor 1
chr1_+_248723397 48.47 ENSRNOT00000072188
mannose-binding protein C-like
chr14_+_22375955 48.36 ENSRNOT00000063915
ENSRNOT00000034784
UDP-glucuronosyltransferase 2 family, member 37
chr17_+_22619891 48.32 ENSRNOT00000060403
androgen-dependent TFPI-regulating protein
chr16_-_7007287 47.24 ENSRNOT00000041216
inter-alpha trypsin inhibitor, heavy chain 3
chr8_+_50537009 47.03 ENSRNOT00000080658
apolipoprotein A4
chr10_+_56662242 47.01 ENSRNOT00000086919
asialoglycoprotein receptor 1
chr5_-_19368431 46.70 ENSRNOT00000012819
cytochrome P450, family 7, subfamily a, polypeptide 1
chr11_+_65022100 46.23 ENSRNOT00000003934
nuclear receptor subfamily 1, group I, member 2
chr7_-_2677199 46.15 ENSRNOT00000043908
apolipoprotein N
chr8_+_50559126 45.87 ENSRNOT00000024918
apolipoprotein A5
chr10_+_56662561 43.29 ENSRNOT00000025254
asialoglycoprotein receptor 1
chr1_-_170431073 42.78 ENSRNOT00000024710
hemopexin
chr7_-_102298522 42.71 ENSRNOT00000006273
alpha-1-B glycoprotein
chr4_-_30338679 42.38 ENSRNOT00000012050
paraoxonase 3
chr8_-_77398156 42.34 ENSRNOT00000091858
ENSRNOT00000085349
ENSRNOT00000082763
lipase C, hepatic type
chr1_+_229030233 42.26 ENSRNOT00000084503
glycine-N-acyltransferase-like 1
chr12_+_38828444 42.18 ENSRNOT00000001809
4-hydroxyphenylpyruvate dioxygenase
chr17_+_69468427 41.77 ENSRNOT00000058413
similar to 20-alpha-hydroxysteroid dehydrogenase
chr9_+_81968332 41.52 ENSRNOT00000023152
cytochrome P450, family 27, subfamily a, polypeptide 1
chr18_+_70733872 41.35 ENSRNOT00000067018
acetyl-CoA acyltransferase 2
chr4_-_176679815 40.59 ENSRNOT00000090122
glycogen synthase 2
chr13_-_56877611 40.50 ENSRNOT00000079040
ENSRNOT00000017195
complement factor H-related 1
chr13_-_56693968 40.44 ENSRNOT00000060160

chr1_-_76780230 40.25 ENSRNOT00000002046
alcohol sulfotransferase-like
chr5_+_134492756 40.24 ENSRNOT00000012888
ENSRNOT00000057095
ENSRNOT00000051385
cytochrome P450, family 4, subfamily a, polypeptide 1
chr12_+_10636275 38.73 ENSRNOT00000001285
cytochrome P450, family 3, subfamily a, polypeptide 18
chr19_+_15294248 38.39 ENSRNOT00000024622
carboxylesterase 1F
chr19_+_50246402 37.92 ENSRNOT00000018795
hydroxysteroid (17-beta) dehydrogenase 2
chr5_+_79179417 37.73 ENSRNOT00000010454
orosomucoid 1
chr8_-_50531423 37.47 ENSRNOT00000090985
ENSRNOT00000074942
apolipoprotein C3
chr5_-_124403195 36.46 ENSRNOT00000067850
complement C8 alpha chain
chr9_+_100281339 36.43 ENSRNOT00000029127
alanine-glyoxylate aminotransferase
chr2_-_243407608 36.04 ENSRNOT00000014631
microsomal triglyceride transfer protein
chr1_+_189241593 35.66 ENSRNOT00000046025
acyl-CoA synthetase medium-chain family member 5
chr12_+_9446940 35.17 ENSRNOT00000074791
ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
chr5_+_124300477 34.98 ENSRNOT00000010100
complement C8 beta chain
chr1_-_224533219 34.84 ENSRNOT00000051289
integral membrane transport protein UST5r
chr16_-_81822716 34.02 ENSRNOT00000026677
coagulation factor X
chr2_+_60337667 33.50 ENSRNOT00000024035
alanine-glyoxylate aminotransferase 2
chr9_-_4945352 33.50 ENSRNOT00000082530
sulfotransferase family 1C member 3
chr10_+_96639924 33.44 ENSRNOT00000004756
apolipoprotein H
chr7_-_123621102 33.35 ENSRNOT00000046024
cytochrome P450, family 2, subfamily d, polypeptide 5
chr10_-_46404642 32.79 ENSRNOT00000083698
phosphatidylethanolamine N-methyltransferase
chr3_-_127500709 32.72 ENSRNOT00000006330
hydroxyacid oxidase 1
chr13_-_47397890 32.55 ENSRNOT00000005505
complement component 4 binding protein, beta
chr5_-_134207847 32.43 ENSRNOT00000083686
ENSRNOT00000088209
ENSRNOT00000051252
cytochrome P450, family 4, subfamily a, polypeptide 2
chr10_+_64952119 32.40 ENSRNOT00000012154
pipecolic acid and sarcosine oxidase
chr10_+_14240219 32.20 ENSRNOT00000020233
insulin-like growth factor binding protein, acid labile subunit
chr2_+_147496229 32.12 ENSRNOT00000022105
transmembrane 4 L six family member 4
chr2_+_20857202 31.95 ENSRNOT00000078919
acyl-CoA thioesterase 12
chr17_+_72160735 31.37 ENSRNOT00000038817
inter-alpha-trypsin inhibitor heavy chain 2
chrX_-_1848904 31.37 ENSRNOT00000010984
regucalcin
chr8_+_112594691 31.26 ENSRNOT00000038383
ENSRNOT00000081281
acyl-CoA dehydrogenase family, member 11
chr1_+_16910069 30.99 ENSRNOT00000020015
aldehyde dehydrogenase 8 family, member A1
chr5_-_126911520 30.97 ENSRNOT00000091521
deiodinase, iodothyronine, type I
chr3_-_2727616 30.65 ENSRNOT00000061904
complement C8 gamma chain
chr16_+_18690649 30.58 ENSRNOT00000015190
methionine adenosyltransferase 1A
chr1_-_258875572 30.35 ENSRNOT00000093005
cytochrome P450, family 2, subfamily c, polypeptide 13
chr13_+_56598957 30.14 ENSRNOT00000016944
ENSRNOT00000080335
ENSRNOT00000089913
coagulation factor XIII B chain
chr16_+_54164431 30.05 ENSRNOT00000090763
fibrinogen-like 1
chr1_+_107344904 29.81 ENSRNOT00000082582
growth arrest-specific 2
chr10_-_62273119 29.77 ENSRNOT00000004322
serpin family F member 2
chr7_-_78847974 29.33 ENSRNOT00000006004
dihydropyrimidinase
chr13_-_56763981 29.29 ENSRNOT00000087916
complement factor H-related protein B
chr1_+_282567674 29.17 ENSRNOT00000090543
carboxylesterase 2I
chr9_+_95274707 28.95 ENSRNOT00000045163
UDP glucuronosyltransferase family 1 member A5
chr6_+_56846789 28.95 ENSRNOT00000032108
alkylglycerol monooxygenase
chr1_-_259287684 28.78 ENSRNOT00000054724
cytochrome P450, family 2, subfamily c, polypeptide 22
chr1_+_213511874 28.50 ENSRNOT00000078080
ENSRNOT00000016883
cytochrome P450, family 2, subfamily e, polypeptide 1
chr1_-_89539210 28.29 ENSRNOT00000077462
ENSRNOT00000028644
hepsin
chr13_+_78805347 28.22 ENSRNOT00000003748
serpin family C member 1
chr2_+_181987217 27.70 ENSRNOT00000034521
fibrinogen gamma chain
chr4_-_50200328 27.68 ENSRNOT00000060530
aminoadipate-semialdehyde synthase
chr8_+_59507990 26.99 ENSRNOT00000018003
hydroxylysine kinase
chr14_+_22724070 26.72 ENSRNOT00000089471
UDP glucuronosyltransferase 2 family, polypeptide B10
chr1_+_83653234 26.62 ENSRNOT00000085008
ENSRNOT00000084230
ENSRNOT00000090071
cytochrome P450, family 2, subfamily a, polypeptide 1
chr9_+_100285804 26.24 ENSRNOT00000079305
alanine-glyoxylate aminotransferase
chr9_+_95256627 26.19 ENSRNOT00000025291
UDP glucuronosyltransferase family 1 member A5
chr17_+_76002275 26.12 ENSRNOT00000092665
ENSRNOT00000086701
enoyl CoA hydratase domain containing 3
chr17_-_43537293 25.94 ENSRNOT00000091749
solute carrier family 17 member 3
chr9_+_16924520 25.84 ENSRNOT00000025094
solute carrier family 22 member 7
chr11_-_87924816 25.80 ENSRNOT00000031819
serpin family D member 1
chr1_+_83933942 25.77 ENSRNOT00000068690
cytochrome P450, family 2, subfamily f, polypeptide 4
chr11_-_81444375 25.71 ENSRNOT00000058479
ENSRNOT00000078131
ENSRNOT00000080949
ENSRNOT00000080562
ENSRNOT00000084867
kininogen 1
chr1_+_282568287 25.68 ENSRNOT00000015997
carboxylesterase 2I
chr8_-_50539331 25.64 ENSRNOT00000088997

chr5_-_134484839 25.51 ENSRNOT00000045571
ENSRNOT00000012681
cytochrome P450, family 4, subfamily a, polypeptide 2
chr17_-_417480 25.23 ENSRNOT00000023685
fructose-bisphosphatase 1
chr16_+_50179458 24.78 ENSRNOT00000041946
coagulation factor XI
chr16_-_81834945 24.30 ENSRNOT00000037806
coagulation factor VII
chr5_-_9429859 24.13 ENSRNOT00000009462
alcohol dehydrogenase, iron containing, 1
chr6_+_127946686 24.06 ENSRNOT00000082680
Ab1-233
chr10_-_50402616 24.06 ENSRNOT00000004546
heparan sulfate-glucosamine 3-sulfotransferase 3B1
chr12_+_19196611 23.92 ENSRNOT00000001801
alpha-2-glycoprotein 1, zinc-binding
chr2_-_23256158 23.89 ENSRNOT00000015336
betaine-homocysteine S-methyltransferase
chr10_+_56710965 23.82 ENSRNOT00000087121
asialoglycoprotein receptor 2
chr4_-_115332052 23.53 ENSRNOT00000017643
C-type lectin domain family 4, member F
chr9_-_19880346 23.06 ENSRNOT00000014051
cytochrome P450, family 39, subfamily a, polypeptide 1
chr15_+_57290849 23.01 ENSRNOT00000014909
carboxypeptidase B2
chr1_-_219312240 22.97 ENSRNOT00000066691
similar to hypothetical protein MGC37914
chr1_-_76614279 22.86 ENSRNOT00000041367
ENSRNOT00000089371
alcohol sulfotransferase-like
chr5_+_160306727 22.86 ENSRNOT00000016648
agmatinase
chr13_-_47377703 22.84 ENSRNOT00000005461
complement component 4 binding protein, alpha
chr18_-_40716686 22.82 ENSRNOT00000000172
cysteine dioxygenase type 1
chr1_-_164143818 22.68 ENSRNOT00000022557
diacylglycerol O-acyltransferase 2
chr2_+_54466280 22.65 ENSRNOT00000033112
complement C6
chr1_-_80617057 22.63 ENSRNOT00000080453
apolipoprotein E
chr8_-_56393233 22.42 ENSRNOT00000016263
ferredoxin 1
chr7_+_71057911 22.42 ENSRNOT00000037218
retinol dehydrogenase 16 (all-trans)
chr4_+_109497962 22.23 ENSRNOT00000057869
regenerating family member 1 alpha
chr3_-_55587946 21.97 ENSRNOT00000075107
ATP binding cassette subfamily B member 11
chr5_+_124476168 21.91 ENSRNOT00000077754
similar to novel protein
chr8_+_85553734 21.76 ENSRNOT00000044944
glutathione S-transferase alpha 5
chr6_-_104631355 21.65 ENSRNOT00000007825
solute carrier family 10 member 1
chr8_+_115151627 21.60 ENSRNOT00000064252
abhydrolase domain containing 14b
chr6_+_80188943 21.49 ENSRNOT00000059335
melanoma inhibitory activity 2
chr7_+_2605719 21.45 ENSRNOT00000018737
glutaminase 2
chr5_-_59165160 21.45 ENSRNOT00000029035
family with sequence similarity 221, member B
chr9_+_4269160 21.44 ENSRNOT00000050420
sulfotransferase family 1C member 2
chr10_-_103848035 21.10 ENSRNOT00000029001
fatty acid desaturase 6
chr17_+_56935451 21.04 ENSRNOT00000058966
similar to hypothetical protein 4930474N05
chr2_-_236480502 20.87 ENSRNOT00000015020
sphingomyelin synthase 2
chr4_+_57855416 20.80 ENSRNOT00000029608
carboxypeptidase A2
chr5_-_160383782 20.53 ENSRNOT00000018349
chymotrypsin-like elastase family, member 2A
chr9_+_27408333 20.49 ENSRNOT00000088416
glutathione S-transferase alpha 3
chr9_-_4327679 20.28 ENSRNOT00000073468
sulfotransferase 1C1-like
chr10_-_57653359 20.17 ENSRNOT00000089638
derlin 2
chr1_-_219311502 20.16 ENSRNOT00000085439
similar to hypothetical protein MGC37914
chr20_-_8202924 20.13 ENSRNOT00000071399
transmembrane protein 217
chr3_-_80012750 20.10 ENSRNOT00000018154
nuclear receptor subfamily 1, group H, member 3
chr4_-_70747226 20.03 ENSRNOT00000044960
anionic trypsin-2-like
chr5_-_78042556 19.86 ENSRNOT00000076005

chr4_+_163162211 19.77 ENSRNOT00000082537
C-type lectin domain family 1, member B
chr4_+_57952982 19.74 ENSRNOT00000014465
carboxypeptidase A1
chr7_-_123655896 19.50 ENSRNOT00000012413
cytochrome P450, family 2, subfamily d, polypeptide 2
chr14_-_19072677 19.39 ENSRNOT00000060548
similar to alpha-fetoprotein
chr9_+_9721105 19.34 ENSRNOT00000073042
ENSRNOT00000075494
complement C3
chr4_+_71621729 19.20 ENSRNOT00000022275
glutathione S-transferase kappa 1
chr6_+_2216623 19.15 ENSRNOT00000008045
regulator of microtubule dynamics 2
chr16_+_74865516 19.05 ENSRNOT00000058072
ATPase copper transporting beta
chr4_+_100465170 19.05 ENSRNOT00000019571
retinol saturase
chr3_+_171213936 19.02 ENSRNOT00000031586
phosphoenolpyruvate carboxykinase 1
chr11_+_74057361 18.91 ENSRNOT00000048746
carboxypeptidase N subunit 2
chr18_+_32964763 18.68 ENSRNOT00000019467
poly(A) binding protein, cytoplasmic 2
chr1_-_84856309 18.66 ENSRNOT00000079567

chr4_-_68349273 18.65 ENSRNOT00000016251
protease, serine, 37
chr19_-_53477420 18.55 ENSRNOT00000071344
hypothetical protein LOC687560
chr13_+_91080341 18.39 ENSRNOT00000000058
C-reactive protein
chr1_+_263554453 18.35 ENSRNOT00000070861
ATP binding cassette subfamily C member 2
chr1_+_48273611 18.26 ENSRNOT00000022254
ENSRNOT00000022068
solute carrier family 22 member 1
chr11_-_72614176 18.21 ENSRNOT00000002366
3-hydroxybutyrate dehydrogenase 1
chr4_-_169036950 18.19 ENSRNOT00000011295
germ cell associated 1
chr8_+_71167305 18.19 ENSRNOT00000021337
RNA binding protein with multiple splicing 2
chr3_+_54253949 18.17 ENSRNOT00000010018
Beta-1,3-galactosyltransferase 1
chr7_+_93975451 18.09 ENSRNOT00000011379
collectin subfamily member 10
chr2_-_196113149 18.06 ENSRNOT00000088465
selenium binding protein 1
chr4_+_174181644 18.04 ENSRNOT00000011555
capping actin protein of muscle Z-line alpha subunit 3
chr9_-_26707571 17.97 ENSRNOT00000080948

chr13_-_57080491 17.96 ENSRNOT00000017749
ENSRNOT00000086572
ENSRNOT00000060111
complement factor H
chr1_+_226234074 17.92 ENSRNOT00000027834
fatty acid desaturase 1
chr1_-_22625204 17.92 ENSRNOT00000021694
vanin 1
chr19_+_15094309 17.83 ENSRNOT00000083500
carboxylesterase 1F
chr4_-_22192474 17.80 ENSRNOT00000043822
ATP binding cassette subfamily B member 1A
chr14_-_89238094 17.64 ENSRNOT00000006818
Sad1 and UNC84 domain containing 3
chr13_-_80819218 17.55 ENSRNOT00000072922
flavin containing monooxygenase 6
chr6_-_7961207 17.27 ENSRNOT00000007174
ATP binding cassette subfamily G member 5
chr1_-_224389389 17.16 ENSRNOT00000077408
ENSRNOT00000050010
integral membrane transport protein UST4r
chr10_-_104564480 17.12 ENSRNOT00000008525
galactokinase 1
chr5_-_75116490 17.06 ENSRNOT00000042788
thioredoxin domain containing 8
chr17_+_76306585 16.95 ENSRNOT00000065978
dehydrogenase E1 and transketolase domain containing 1
chr5_-_134638150 16.92 ENSRNOT00000013480
testis expressed 38
chr1_+_20856187 16.88 ENSRNOT00000071726
small leucine-rich protein 1
chr8_-_111721303 16.86 ENSRNOT00000045628
ENSRNOT00000012725
transferrin
chr5_+_69833225 16.83 ENSRNOT00000013759
nipsnap homolog 3B
chr2_+_58462949 16.79 ENSRNOT00000080618
NAD kinase 2, mitochondrial
chr7_-_117680004 16.73 ENSRNOT00000040422
solute carrier family 39 member 4
chr4_-_77489535 16.67 ENSRNOT00000008728
protein disulfide isomerase family A, member 4
chr13_+_78812394 16.65 ENSRNOT00000076043
serpin family C member 1
chr11_+_61609370 16.60 ENSRNOT00000088880
ENSRNOT00000082533
GRAM domain containing 1C
chr3_-_14229067 16.57 ENSRNOT00000025534
ENSRNOT00000092865
complement C5
chr10_-_29450644 16.55 ENSRNOT00000087937
adrenoceptor alpha 1B

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr1i3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
50.1 150.2 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
45.9 45.9 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
32.1 96.2 GO:0019265 glycine biosynthetic process, by transamination of glyoxylate(GO:0019265)
27.1 108.6 GO:0048252 lauric acid metabolic process(GO:0048252)
24.3 24.3 GO:1904612 response to 2,3,7,8-tetrachlorodibenzodioxine(GO:1904612)
20.8 62.4 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
19.8 79.3 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
19.7 59.0 GO:0051977 lysophospholipid transport(GO:0051977)
19.6 78.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
19.5 58.6 GO:0043606 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) formamide metabolic process(GO:0043606)
18.9 56.7 GO:0010034 response to acetate(GO:0010034)
18.5 55.4 GO:0045959 negative regulation of complement activation, classical pathway(GO:0045959)
18.4 18.4 GO:0050787 detoxification of mercury ion(GO:0050787)
15.2 60.6 GO:0019474 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
14.3 28.5 GO:0016098 monoterpenoid metabolic process(GO:0016098)
14.2 42.6 GO:0042412 taurine biosynthetic process(GO:0042412)
14.0 42.0 GO:0001905 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
13.8 41.5 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
12.3 37.0 GO:0002933 lipid hydroxylation(GO:0002933)
12.3 36.8 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
11.4 91.4 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
11.3 45.0 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
11.2 11.2 GO:0009436 glyoxylate catabolic process(GO:0009436)
10.8 10.8 GO:0046487 glyoxylate metabolic process(GO:0046487)
10.5 31.4 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
10.3 93.1 GO:0046618 drug export(GO:0046618)
10.2 102.2 GO:0018298 protein-chromophore linkage(GO:0018298)
10.2 132.1 GO:0042178 xenobiotic catabolic process(GO:0042178)
9.9 29.8 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
9.7 29.2 GO:0015680 intracellular copper ion transport(GO:0015680)
9.4 28.3 GO:0034769 basement membrane disassembly(GO:0034769)
9.2 55.2 GO:0006572 tyrosine catabolic process(GO:0006572)
9.0 45.0 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
8.6 17.3 GO:0006114 glycerol biosynthetic process(GO:0006114)
8.6 25.9 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
8.6 60.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
8.5 42.3 GO:1904729 regulation of intestinal lipid absorption(GO:1904729)
8.3 25.0 GO:0042196 chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
8.2 32.9 GO:0009441 glycolate metabolic process(GO:0009441)
8.0 23.9 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
7.6 106.4 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
7.5 22.5 GO:1904170 phospholipid transfer to membrane(GO:0006649) NAD transport(GO:0043132) regulation of bleb assembly(GO:1904170)
7.4 29.8 GO:0003072 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
7.4 7.4 GO:0042853 L-alanine catabolic process(GO:0042853)
7.4 51.5 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
7.3 29.3 GO:0006212 uracil catabolic process(GO:0006212)
7.3 50.8 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
7.2 65.1 GO:0052697 xenobiotic glucuronidation(GO:0052697)
7.0 21.0 GO:0010133 proline catabolic process to glutamate(GO:0010133)
6.9 20.8 GO:0006543 glutamine catabolic process(GO:0006543)
6.8 20.5 GO:0046223 toxin catabolic process(GO:0009407) mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) secondary metabolite catabolic process(GO:0090487) organic heteropentacyclic compound catabolic process(GO:1901377)
6.7 60.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
6.7 26.6 GO:0009804 coumarin metabolic process(GO:0009804)
6.6 85.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
6.5 64.8 GO:0070989 oxidative demethylation(GO:0070989)
6.4 51.5 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
6.3 56.9 GO:0070314 G1 to G0 transition(GO:0070314)
6.3 25.2 GO:0046351 disaccharide biosynthetic process(GO:0046351)
6.1 30.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
6.1 24.4 GO:0006741 NADP biosynthetic process(GO:0006741)
5.9 17.8 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
5.8 186.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
5.7 17.1 GO:0006059 hexitol metabolic process(GO:0006059)
5.6 16.7 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
5.6 16.7 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
5.5 16.6 GO:0045819 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982) positive regulation of glycogen catabolic process(GO:0045819)
5.5 21.8 GO:0006565 L-serine catabolic process(GO:0006565)
5.4 16.2 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
5.3 10.7 GO:0006710 androgen catabolic process(GO:0006710)
5.3 15.9 GO:1990743 protein sialylation(GO:1990743)
5.3 47.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
5.2 25.9 GO:0008295 spermidine biosynthetic process(GO:0008295)
5.2 10.3 GO:0009751 response to salicylic acid(GO:0009751)
5.1 15.2 GO:0008592 regulation of Toll signaling pathway(GO:0008592) negative regulation of Toll signaling pathway(GO:0045751)
5.0 15.1 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
5.0 35.1 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
4.9 14.8 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
4.9 43.8 GO:0015747 urate transport(GO:0015747)
4.9 48.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
4.8 14.3 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
4.6 4.6 GO:1904054 regulation of cholangiocyte proliferation(GO:1904054) positive regulation of cholangiocyte proliferation(GO:1904056)
4.5 22.7 GO:0071400 cellular response to oleic acid(GO:0071400)
4.5 63.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
4.5 17.9 GO:0035565 regulation of pronephros size(GO:0035565)
4.4 22.0 GO:0006558 L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221)
4.4 13.1 GO:0060166 olfactory pit development(GO:0060166)
4.4 13.1 GO:0010796 regulation of multivesicular body size(GO:0010796)
4.2 21.2 GO:0015793 glycerol transport(GO:0015793)
4.2 12.6 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
4.1 57.6 GO:0035634 response to stilbenoid(GO:0035634)
4.1 8.2 GO:0016487 sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
4.1 32.5 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
4.0 12.1 GO:0042414 epinephrine metabolic process(GO:0042414)
4.0 40.0 GO:0070995 NADPH oxidation(GO:0070995)
4.0 12.0 GO:1902267 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
4.0 71.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
3.9 27.6 GO:0006477 protein sulfation(GO:0006477)
3.9 15.8 GO:0009992 cellular water homeostasis(GO:0009992)
3.9 7.8 GO:0043605 cellular amide catabolic process(GO:0043605)
3.9 27.4 GO:0006569 tryptophan catabolic process(GO:0006569) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
3.9 89.5 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
3.8 7.6 GO:0030638 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
3.8 11.3 GO:0042732 D-xylose metabolic process(GO:0042732)
3.8 3.8 GO:0097212 lysosomal membrane organization(GO:0097212)
3.7 22.5 GO:0050917 sensory perception of umami taste(GO:0050917)
3.7 22.3 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
3.7 18.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
3.6 14.5 GO:0097052 L-kynurenine metabolic process(GO:0097052)
3.5 24.8 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
3.5 21.1 GO:0038161 prolactin signaling pathway(GO:0038161)
3.5 10.5 GO:1905204 septum secundum development(GO:0003285) embryonic heart tube anterior/posterior pattern specification(GO:0035054) negative regulation of connective tissue replacement(GO:1905204)
3.5 13.8 GO:1902861 copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
3.4 10.3 GO:0044375 regulation of peroxisome size(GO:0044375)
3.4 10.3 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
3.4 10.2 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
3.4 6.7 GO:2000426 negative regulation of apoptotic cell clearance(GO:2000426)
3.3 13.2 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
3.3 9.9 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
3.3 16.5 GO:0006642 triglyceride mobilization(GO:0006642)
3.2 9.7 GO:0015744 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
3.1 12.5 GO:0001582 detection of chemical stimulus involved in sensory perception of sweet taste(GO:0001582)
3.1 18.4 GO:0031999 negative regulation of fatty acid beta-oxidation(GO:0031999)
3.1 3.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
3.0 9.1 GO:0019303 D-ribose catabolic process(GO:0019303)
3.0 8.9 GO:0044209 purine deoxyribonucleotide biosynthetic process(GO:0009153) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216) AMP salvage(GO:0044209) adenosine biosynthetic process(GO:0046086)
2.9 11.7 GO:1990375 baculum development(GO:1990375)
2.9 8.7 GO:0006574 valine catabolic process(GO:0006574)
2.9 77.1 GO:0019835 cytolysis(GO:0019835)
2.8 14.2 GO:0018158 protein oxidation(GO:0018158)
2.8 14.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
2.8 19.6 GO:0000255 allantoin metabolic process(GO:0000255)
2.8 11.2 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
2.8 2.8 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
2.8 11.0 GO:1903334 positive regulation of protein folding(GO:1903334)
2.8 11.0 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
2.8 5.5 GO:0042369 vitamin D catabolic process(GO:0042369)
2.8 35.8 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
2.7 13.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
2.7 5.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
2.7 10.7 GO:0015879 carnitine transport(GO:0015879)
2.7 2.7 GO:0030647 aminoglycoside antibiotic metabolic process(GO:0030647)
2.7 8.0 GO:0048861 oncostatin-M-mediated signaling pathway(GO:0038165) leukemia inhibitory factor signaling pathway(GO:0048861)
2.7 18.6 GO:0007262 STAT protein import into nucleus(GO:0007262)
2.6 26.4 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
2.6 13.2 GO:1901475 pyruvate transmembrane transport(GO:1901475)
2.6 29.0 GO:0034310 primary alcohol catabolic process(GO:0034310)
2.6 10.5 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
2.5 10.2 GO:1902896 terminal web assembly(GO:1902896)
2.5 12.3 GO:0070541 response to platinum ion(GO:0070541)
2.5 14.7 GO:0016191 synaptic vesicle uncoating(GO:0016191)
2.4 44.0 GO:0001675 acrosome assembly(GO:0001675)
2.4 12.0 GO:0061113 pancreas morphogenesis(GO:0061113)
2.4 16.8 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
2.4 7.2 GO:0009249 protein lipoylation(GO:0009249)
2.4 14.3 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
2.4 4.8 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
2.4 2.4 GO:0060523 prostate epithelial cord elongation(GO:0060523)
2.4 7.1 GO:0060468 prevention of polyspermy(GO:0060468)
2.3 7.0 GO:0002462 tolerance induction to nonself antigen(GO:0002462)
2.3 7.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
2.3 13.9 GO:0015697 quaternary ammonium group transport(GO:0015697)
2.3 9.2 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
2.2 18.0 GO:0030449 regulation of complement activation(GO:0030449)
2.2 6.7 GO:0018094 protein polyglycylation(GO:0018094)
2.2 11.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
2.2 6.6 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
2.2 6.6 GO:0032258 CVT pathway(GO:0032258)
2.2 2.2 GO:0071217 cellular response to external biotic stimulus(GO:0071217)
2.2 19.4 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
2.1 12.8 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
2.0 2.0 GO:0030221 basophil differentiation(GO:0030221)
2.0 6.1 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
2.0 18.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
2.0 24.1 GO:0046485 ether lipid metabolic process(GO:0046485)
2.0 3.9 GO:0072181 mesonephric duct formation(GO:0072181)
2.0 7.8 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.9 3.9 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
1.9 5.8 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
1.9 9.7 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
1.9 9.6 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
1.9 17.0 GO:0051132 NK T cell activation(GO:0051132)
1.9 32.1 GO:0034587 piRNA metabolic process(GO:0034587)
1.9 31.8 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
1.9 7.5 GO:0018992 germ-line sex determination(GO:0018992)
1.8 24.0 GO:0001887 selenium compound metabolic process(GO:0001887)
1.8 20.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
1.8 5.5 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
1.8 5.5 GO:0010041 response to iron(III) ion(GO:0010041)
1.8 7.3 GO:1903874 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
1.8 1.8 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
1.8 7.2 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
1.8 39.4 GO:0008206 bile acid metabolic process(GO:0008206)
1.8 12.5 GO:0046060 dATP metabolic process(GO:0046060)
1.8 8.9 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
1.8 5.3 GO:0061741 vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741)
1.8 49.5 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
1.7 10.5 GO:2000667 positive regulation of interleukin-13 secretion(GO:2000667)
1.7 5.2 GO:0048749 compound eye development(GO:0048749)
1.7 20.6 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
1.7 10.3 GO:0034756 regulation of iron ion transport(GO:0034756) negative regulation of iron ion transport(GO:0034757)
1.7 8.6 GO:0075525 viral translational termination-reinitiation(GO:0075525)
1.7 6.8 GO:1904158 axonemal central apparatus assembly(GO:1904158)
1.7 15.1 GO:0006105 succinate metabolic process(GO:0006105)
1.7 6.7 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
1.7 6.7 GO:0060279 positive regulation of ovulation(GO:0060279)
1.7 14.9 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
1.7 29.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
1.6 6.5 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
1.6 1.6 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
1.6 9.7 GO:0015677 copper ion import(GO:0015677)
1.6 8.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
1.6 24.0 GO:0060046 regulation of acrosome reaction(GO:0060046)
1.6 12.6 GO:0006107 oxaloacetate metabolic process(GO:0006107)
1.6 7.8 GO:0089700 protein kinase D signaling(GO:0089700)
1.5 3.1 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
1.5 7.7 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
1.5 9.2 GO:0090298 negative regulation of mitochondrial DNA replication(GO:0090298)
1.5 7.7 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
1.5 3.1 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
1.5 18.2 GO:0050892 intestinal absorption(GO:0050892)
1.5 1.5 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
1.5 16.5 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
1.5 6.0 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
1.5 11.8 GO:0045821 positive regulation of glycolytic process(GO:0045821)
1.5 13.2 GO:0051026 chiasma assembly(GO:0051026)
1.5 2.9 GO:0060112 generation of ovulation cycle rhythm(GO:0060112)
1.4 5.8 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
1.4 4.3 GO:1901367 response to L-cysteine(GO:1901367)
1.4 4.2 GO:1902996 regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949) neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996) positive regulation of neurofibrillary tangle assembly(GO:1902998)
1.4 7.1 GO:0060005 vestibular reflex(GO:0060005)
1.4 2.8 GO:0002930 trabecular meshwork development(GO:0002930)
1.4 12.6 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
1.4 5.5 GO:0002084 protein depalmitoylation(GO:0002084)
1.4 6.9 GO:0071918 urea transmembrane transport(GO:0071918)
1.4 35.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
1.4 6.8 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
1.4 4.1 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
1.4 49.0 GO:0006635 fatty acid beta-oxidation(GO:0006635)
1.4 20.4 GO:0006695 cholesterol biosynthetic process(GO:0006695)
1.4 10.8 GO:0001920 negative regulation of receptor recycling(GO:0001920)
1.3 2.7 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
1.3 4.0 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.3 4.0 GO:1901094 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
1.3 6.6 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
1.3 31.8 GO:0019369 arachidonic acid metabolic process(GO:0019369)
1.3 3.9 GO:0021539 subthalamus development(GO:0021539)
1.3 9.1 GO:0042737 drug catabolic process(GO:0042737)
1.3 30.0 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
1.3 2.6 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
1.3 16.9 GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
1.3 1.3 GO:0072318 clathrin coat disassembly(GO:0072318)
1.3 3.9 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) N-acetylneuraminate biosynthetic process(GO:0046380) glucosamine-containing compound biosynthetic process(GO:1901073)
1.3 6.3 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
1.3 5.0 GO:0071724 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
1.3 7.5 GO:0021563 glossopharyngeal nerve development(GO:0021563)
1.2 2.5 GO:0036023 embryonic skeletal limb joint morphogenesis(GO:0036023)
1.2 2.5 GO:0002191 cap-dependent translational initiation(GO:0002191)
1.2 4.9 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
1.2 13.5 GO:0006544 glycine metabolic process(GO:0006544)
1.2 25.8 GO:0061436 establishment of skin barrier(GO:0061436)
1.2 4.9 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
1.2 7.3 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
1.2 4.8 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
1.2 21.7 GO:0036158 outer dynein arm assembly(GO:0036158)
1.2 4.8 GO:0002184 cytoplasmic translational termination(GO:0002184)
1.2 3.6 GO:0080154 regulation of fertilization(GO:0080154)
1.2 5.9 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
1.2 33.8 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
1.2 4.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
1.2 2.3 GO:1902219 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
1.2 10.4 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
1.1 2.3 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861) negative regulation of complement-dependent cytotoxicity(GO:1903660)
1.1 5.7 GO:0070202 regulation of establishment of protein localization to chromosome(GO:0070202)
1.1 3.4 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
1.1 17.0 GO:0006264 mitochondrial DNA replication(GO:0006264)
1.1 7.8 GO:0006706 steroid catabolic process(GO:0006706)
1.1 3.3 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
1.1 2.2 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
1.1 6.6 GO:0090367 negative regulation of mRNA modification(GO:0090367)
1.1 4.4 GO:0070873 regulation of polysaccharide metabolic process(GO:0032881) regulation of glycogen metabolic process(GO:0070873)
1.1 5.5 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
1.1 8.8 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
1.1 24.1 GO:0033014 tetrapyrrole biosynthetic process(GO:0033014)
1.1 4.3 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
1.1 6.5 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
1.1 3.2 GO:1904956 regulation of endodermal cell fate specification(GO:0042663) regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
1.1 8.6 GO:0010815 bradykinin catabolic process(GO:0010815)
1.1 18.0 GO:0035404 histone-serine phosphorylation(GO:0035404)
1.0 1.0 GO:1903223 positive regulation of oxidative stress-induced neuron death(GO:1903223)
1.0 5.2 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
1.0 2.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
1.0 5.1 GO:0015801 aromatic amino acid transport(GO:0015801)
1.0 4.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
1.0 8.1 GO:0071318 cellular response to ATP(GO:0071318)
1.0 2.0 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
1.0 3.0 GO:0002396 MHC protein complex assembly(GO:0002396) MHC class II protein complex assembly(GO:0002399) peptide antigen assembly with MHC protein complex(GO:0002501) peptide antigen assembly with MHC class II protein complex(GO:0002503)
1.0 11.0 GO:0044247 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
1.0 13.8 GO:0070633 transepithelial transport(GO:0070633)
1.0 3.9 GO:1904717 regulation of AMPA glutamate receptor clustering(GO:1904717)
1.0 7.8 GO:1990034 calcium ion export from cell(GO:1990034)
1.0 3.9 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
1.0 2.9 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
1.0 6.7 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
1.0 8.6 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
1.0 3.8 GO:0009642 response to light intensity(GO:0009642)
1.0 13.3 GO:0045056 transcytosis(GO:0045056)
1.0 3.8 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.9 14.0 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.9 2.8 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.9 2.8 GO:0046051 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051) guanosine-containing compound biosynthetic process(GO:1901070)
0.9 4.6 GO:0019520 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.9 1.8 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
0.9 3.6 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.9 2.7 GO:0072053 renal inner medulla development(GO:0072053)
0.9 6.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.9 2.7 GO:0046333 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.9 4.4 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.9 3.5 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.9 4.3 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.9 1.7 GO:0019321 pentose metabolic process(GO:0019321)
0.8 3.4 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.8 19.3 GO:0042311 vasodilation(GO:0042311)
0.8 8.4 GO:0006958 complement activation, classical pathway(GO:0006958)
0.8 3.3 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.8 2.5 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.8 2.5 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.8 25.6 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.8 10.7 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.8 2.5 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
0.8 0.8 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.8 1.6 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.8 3.3 GO:1902534 single-organism membrane invagination(GO:1902534)
0.8 2.4 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.8 3.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.8 2.4 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.8 4.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.8 1.6 GO:0002488 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
0.8 4.0 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.8 8.0 GO:0006855 drug transmembrane transport(GO:0006855)
0.8 6.3 GO:0022417 protein maturation by protein folding(GO:0022417)
0.8 70.3 GO:0007586 digestion(GO:0007586)
0.8 7.1 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.8 13.3 GO:0033327 Leydig cell differentiation(GO:0033327)
0.8 3.8 GO:0044704 mating plug formation(GO:0042628) single-organism reproductive behavior(GO:0044704) post-mating behavior(GO:0045297)
0.8 2.3 GO:0032978 protein insertion into membrane from inner side(GO:0032978)
0.8 2.3 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.8 2.3 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.7 2.2 GO:0032532 regulation of microvillus length(GO:0032532)
0.7 4.5 GO:0055091 phospholipid homeostasis(GO:0055091)
0.7 2.2 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.7 5.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.7 7.4 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.7 3.7 GO:0001757 somite specification(GO:0001757)
0.7 2.2 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.7 0.7 GO:0036446 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.7 18.2 GO:0060416 response to growth hormone(GO:0060416)
0.7 4.3 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.7 2.2 GO:1990790 response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
0.7 7.9 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.7 1.4 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.7 2.1 GO:0036159 inner dynein arm assembly(GO:0036159)
0.7 1.4 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.7 7.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.7 2.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.7 17.4 GO:0006739 NADP metabolic process(GO:0006739)
0.7 2.8 GO:0009624 response to nematode(GO:0009624)
0.7 1.4 GO:0042253 granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.7 2.1 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.7 2.1 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.7 2.1 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.7 2.7 GO:0051958 methotrexate transport(GO:0051958)
0.7 7.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.7 5.4 GO:0050667 homocysteine metabolic process(GO:0050667)
0.7 1.4 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.7 0.7 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.7 3.4 GO:0002001 renin secretion into blood stream(GO:0002001)
0.7 7.4 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.7 5.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.7 12.6 GO:0042572 retinol metabolic process(GO:0042572)
0.7 4.0 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.7 4.0 GO:0015886 heme transport(GO:0015886)
0.6 1.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.6 1.3 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.6 3.8 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.6 4.5 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.6 1.3 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.6 15.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.6 1.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.6 3.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.6 5.6 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.6 3.7 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.6 9.1 GO:0046337 phosphatidylethanolamine metabolic process(GO:0046337)
0.6 1.8 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.6 2.4 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.6 1.8 GO:1904640 response to methionine(GO:1904640)
0.6 2.4 GO:0046098 guanine metabolic process(GO:0046098)
0.6 1.8 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.6 4.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.6 13.4 GO:0030220 platelet formation(GO:0030220)
0.6 1.7 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.6 2.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.6 1.7 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.6 2.3 GO:0032275 luteinizing hormone secretion(GO:0032275)
0.6 2.3 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.6 7.4 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.6 1.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.6 5.0 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.6 5.6 GO:0046415 urate metabolic process(GO:0046415)
0.6 5.6 GO:0001845 phagolysosome assembly(GO:0001845)
0.6 1.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.6 3.9 GO:0042448 progesterone metabolic process(GO:0042448)
0.5 1.1 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.5 6.0 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.5 3.3 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.5 4.4 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.5 7.1 GO:0034063 stress granule assembly(GO:0034063)
0.5 3.3 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.5 0.5 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.5 15.7 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.5 1.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.5 3.2 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.5 5.3 GO:0006089 lactate metabolic process(GO:0006089)
0.5 5.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.5 6.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.5 6.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.5 1.6 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.5 7.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.5 1.5 GO:0030091 protein repair(GO:0030091)
0.5 6.1 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.5 2.5 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.5 2.0 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.5 5.6 GO:0007028 cytoplasm organization(GO:0007028)
0.5 8.6 GO:0043486 histone exchange(GO:0043486)
0.5 1.5 GO:0061144 alveolar secondary septum development(GO:0061144)
0.5 4.4 GO:0009062 fatty acid catabolic process(GO:0009062)
0.5 3.4 GO:0051177 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
0.5 2.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.5 1.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.5 1.4 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.5 14.1 GO:0016125 sterol metabolic process(GO:0016125)
0.5 13.6 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.5 5.1 GO:0030259 lipid glycosylation(GO:0030259)
0.5 4.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.5 3.7 GO:0009650 UV protection(GO:0009650)
0.5 4.6 GO:0006541 glutamine metabolic process(GO:0006541)
0.5 4.1 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.5 3.6 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.5 0.9 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.4 239.6 GO:0055114 oxidation-reduction process(GO:0055114)
0.4 4.0 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.4 3.1 GO:0046689 response to mercury ion(GO:0046689)
0.4 1.8 GO:0006004 fucose metabolic process(GO:0006004)
0.4 0.9 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.4 1.3 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.4 7.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.4 1.8 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.4 4.8 GO:0033194 response to hydroperoxide(GO:0033194)
0.4 8.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.4 0.9 GO:0097187 dentinogenesis(GO:0097187)
0.4 8.2 GO:0006458 'de novo' protein folding(GO:0006458)
0.4 3.8 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.4 7.6 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.4 1.2 GO:0071105 response to interleukin-11(GO:0071105)
0.4 0.8 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.4 5.3 GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901028)
0.4 2.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.4 0.4 GO:0040009 regulation of growth rate(GO:0040009)
0.4 2.7 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.4 8.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.4 4.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.4 1.9 GO:0051182 coenzyme transport(GO:0051182)
0.4 1.5 GO:0048539 bone marrow development(GO:0048539)
0.4 1.5 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.4 1.5 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.4 4.5 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.4 6.2 GO:0003351 epithelial cilium movement(GO:0003351)
0.4 6.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.4 4.0 GO:1900120 regulation of receptor binding(GO:1900120)
0.4 6.8 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.4 1.4 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.4 2.5 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.3 2.1 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.3 4.5 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.3 4.8 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.3 5.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.3 1.0 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.3 1.3 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.3 1.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 1.0 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.3 38.5 GO:0007286 spermatid development(GO:0007286)
0.3 1.2 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.3 3.3 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.3 0.6 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.3 3.6 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.3 1.5 GO:0032366 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.3 7.7 GO:0032527 protein exit from endoplasmic reticulum(GO:0032527)
0.3 0.6 GO:2000424 regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.3 2.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.3 3.8 GO:0048535 lymph node development(GO:0048535)
0.3 3.7 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.3 2.5 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.3 2.0 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.3 1.4 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.3 1.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.3 3.5 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.3 8.2 GO:0055088 lipid homeostasis(GO:0055088)
0.3 3.4 GO:0051013 microtubule severing(GO:0051013)
0.3 1.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.3 6.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.3 1.0 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.3 9.9 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.3 4.0 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.2 0.7 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.2 1.2 GO:0045617 negative regulation of epidermal cell differentiation(GO:0045605) negative regulation of keratinocyte differentiation(GO:0045617)
0.2 0.7 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.2 1.4 GO:0035878 nail development(GO:0035878)
0.2 0.2 GO:0010888 negative regulation of lipid storage(GO:0010888)
0.2 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 0.5 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.2 1.6 GO:0007379 segment specification(GO:0007379)
0.2 0.9 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.2 6.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.2 1.3 GO:0048496 maintenance of organ identity(GO:0048496)
0.2 1.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.2 3.3 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.2 2.0 GO:0048617 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.2 3.4 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.2 0.2 GO:0090365 regulation of mRNA modification(GO:0090365)
0.2 2.5 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.2 0.8 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.2 4.0 GO:0045116 protein neddylation(GO:0045116)
0.2 1.0 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.2 2.6 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.2 0.4 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.2 0.8 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.2 1.6 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.2 8.1 GO:0032543 mitochondrial translation(GO:0032543)
0.2 2.1 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.2 2.1 GO:0090382 phagosome maturation(GO:0090382)
0.2 0.4 GO:0007529 establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.2 0.7 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.2 1.6 GO:0019363 nicotinamide nucleotide biosynthetic process(GO:0019359) pyridine nucleotide biosynthetic process(GO:0019363)
0.2 3.4 GO:0044458 motile cilium assembly(GO:0044458)
0.2 2.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.2 2.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 0.9 GO:2000392 regulation of lamellipodium morphogenesis(GO:2000392) positive regulation of lamellipodium morphogenesis(GO:2000394)
0.2 5.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.2 0.5 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 1.0 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 4.8 GO:0009311 oligosaccharide metabolic process(GO:0009311)
0.1 0.7 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 0.3 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.1 5.4 GO:0006400 tRNA modification(GO:0006400)
0.1 0.5 GO:0002921 negative regulation of humoral immune response(GO:0002921)
0.1 0.3 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.1 1.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 160.0 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.5 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 1.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.1 2.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.7 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133)
0.1 0.3 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.1 1.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 3.7 GO:0046605 regulation of centrosome cycle(GO:0046605)
0.1 1.4 GO:2000191 regulation of fatty acid transport(GO:2000191)
0.1 0.4 GO:0006691 leukotriene metabolic process(GO:0006691)
0.1 0.3 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.1 0.2 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
0.1 1.3 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 0.7 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 1.9 GO:2000352 negative regulation of endothelial cell apoptotic process(GO:2000352)
0.1 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.3 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.4 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.1 0.2 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 0.5 GO:1904117 cellular response to vasopressin(GO:1904117)
0.1 2.0 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 0.3 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 1.3 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.3 GO:0045006 DNA deamination(GO:0045006)
0.1 0.2 GO:0060816 random inactivation of X chromosome(GO:0060816) regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 1.4 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1 2.8 GO:0034502 protein localization to chromosome(GO:0034502)
0.1 1.0 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.1 1.7 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.4 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.1 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 1.0 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.2 GO:0043321 regulation of natural killer cell degranulation(GO:0043321)
0.1 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.5 GO:0043312 neutrophil degranulation(GO:0043312)
0.0 0.7 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.7 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.1 GO:0021571 rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571)
0.0 0.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.6 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.0 0.5 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.2 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.4 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.0 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.4 GO:0021591 ventricular system development(GO:0021591)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.1 GO:0051923 sulfation(GO:0051923)
0.0 0.3 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.3 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.3 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.0 GO:0042256 mature ribosome assembly(GO:0042256)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
23.6 306.2 GO:0042627 chylomicron(GO:0042627)
15.3 107.4 GO:0005579 membrane attack complex(GO:0005579)
15.1 121.2 GO:0005577 fibrinogen complex(GO:0005577)
13.2 79.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
11.7 58.6 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
8.2 82.4 GO:0045179 apical cortex(GO:0045179)
8.0 24.0 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
6.9 34.4 GO:0043159 acrosomal matrix(GO:0043159)
5.8 75.4 GO:0046581 intercellular canaliculus(GO:0046581)
5.8 17.4 GO:0045203 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
5.4 32.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
4.6 13.8 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
4.5 85.6 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
4.4 506.4 GO:0072562 blood microparticle(GO:0072562)
4.4 17.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
4.4 13.1 GO:0000802 transverse filament(GO:0000802)
4.2 20.8 GO:0097413 Lewy body(GO:0097413)
3.9 19.6 GO:0070195 growth hormone receptor complex(GO:0070195)
3.9 11.6 GO:0031308 intrinsic component of nuclear outer membrane(GO:0031308) integral component of nuclear outer membrane(GO:0031309)
3.6 10.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
3.4 20.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
3.2 9.6 GO:0005760 gamma DNA polymerase complex(GO:0005760)
3.1 12.2 GO:1990005 granular vesicle(GO:1990005)
3.0 20.8 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
3.0 26.7 GO:0071546 pi-body(GO:0071546)
2.9 11.4 GO:0030478 actin cap(GO:0030478)
2.7 10.9 GO:0005956 protein kinase CK2 complex(GO:0005956)
2.7 8.1 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
2.7 40.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
2.6 51.3 GO:0005640 nuclear outer membrane(GO:0005640)
2.5 22.5 GO:0032059 bleb(GO:0032059)
2.5 35.0 GO:0042612 MHC class I protein complex(GO:0042612)
2.5 12.5 GO:1903768 sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
2.4 7.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
2.4 7.1 GO:0036117 hyaluranon cable(GO:0036117)
2.2 6.7 GO:0043511 inhibin complex(GO:0043511)
2.2 6.6 GO:1990826 nucleoplasmic periphery of the nuclear pore complex(GO:1990826)
2.2 6.6 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
2.2 13.0 GO:1990357 terminal web(GO:1990357)
2.0 18.2 GO:0098576 lumenal side of membrane(GO:0098576)
1.9 21.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
1.9 5.6 GO:0032807 DNA ligase IV complex(GO:0032807)
1.7 262.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
1.7 15.5 GO:0000138 Golgi trans cisterna(GO:0000138)
1.7 236.7 GO:0001669 acrosomal vesicle(GO:0001669)
1.6 19.8 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
1.6 8.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
1.6 6.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.6 25.5 GO:0030061 mitochondrial crista(GO:0030061)
1.5 15.0 GO:0097550 transcriptional preinitiation complex(GO:0097550)
1.5 43.8 GO:0042588 zymogen granule(GO:0042588)
1.5 7.3 GO:0044316 cone cell pedicle(GO:0044316)
1.4 26.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
1.4 6.8 GO:1990716 axonemal central apparatus(GO:1990716)
1.4 4.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
1.3 32.2 GO:0031528 microvillus membrane(GO:0031528)
1.3 7.9 GO:0001674 female germ cell nucleus(GO:0001674)
1.3 6.4 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
1.2 68.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
1.2 4.8 GO:0018444 translation release factor complex(GO:0018444)
1.2 3.6 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
1.2 11.8 GO:0042587 glycogen granule(GO:0042587)
1.2 19.9 GO:0044215 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
1.1 19.4 GO:0001520 outer dense fiber(GO:0001520)
1.1 840.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
1.1 7.8 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
1.1 19.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
1.1 24.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
1.1 4.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
1.1 3.2 GO:0070421 DNA ligase III-XRCC1 complex(GO:0070421)
1.1 50.2 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
1.0 11.3 GO:0008385 IkappaB kinase complex(GO:0008385)
1.0 3.0 GO:0070557 PCNA-p21 complex(GO:0070557)
1.0 5.9 GO:0030289 protein phosphatase 4 complex(GO:0030289)
1.0 3.9 GO:0001405 presequence translocase-associated import motor(GO:0001405)
1.0 6.7 GO:0002139 stereocilia coupling link(GO:0002139)
0.9 233.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.8 2.5 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.8 25.1 GO:0005581 collagen trimer(GO:0005581)
0.8 19.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.8 11.4 GO:0045180 basal cortex(GO:0045180)
0.7 3.7 GO:0005796 Golgi lumen(GO:0005796)
0.7 8.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.7 4.1 GO:0005879 axonemal microtubule(GO:0005879)
0.7 3.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.7 5.9 GO:0042788 polysomal ribosome(GO:0042788)
0.7 9.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.6 1.9 GO:0005745 m-AAA complex(GO:0005745)
0.6 3.8 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.6 2.5 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.6 1.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.6 2.4 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.6 7.3 GO:0000812 Swr1 complex(GO:0000812)
0.6 3.0 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.6 3.6 GO:0070847 core mediator complex(GO:0070847)
0.6 1.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.6 4.1 GO:0097452 GAIT complex(GO:0097452)
0.6 7.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.5 4.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.5 2.1 GO:0036156 inner dynein arm(GO:0036156)
0.5 27.1 GO:0005811 lipid particle(GO:0005811)
0.5 5.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.5 4.6 GO:0071821 FANCM-MHF complex(GO:0071821)
0.5 2.0 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.5 2.4 GO:1990130 Iml1 complex(GO:1990130)
0.5 13.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.5 5.8 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.5 1.9 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.4 2.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.4 1.3 GO:0060187 cell pole(GO:0060187)
0.4 8.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.4 2.1 GO:0045009 melanosome membrane(GO:0033162) ER-mitochondrion membrane contact site(GO:0044233) chitosome(GO:0045009)
0.4 2.4 GO:1990635 proximal dendrite(GO:1990635)
0.4 6.0 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.4 3.4 GO:0002177 manchette(GO:0002177)
0.4 3.4 GO:0000813 ESCRT I complex(GO:0000813)
0.4 3.5 GO:0031983 vesicle lumen(GO:0031983)
0.4 2.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 1.4 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.3 6.6 GO:0001673 male germ cell nucleus(GO:0001673)
0.3 2.4 GO:0036449 zonula adherens(GO:0005915) microtubule minus-end(GO:0036449)
0.3 2.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.3 2.0 GO:1990246 uniplex complex(GO:1990246)
0.3 2.6 GO:0043202 lysosomal lumen(GO:0043202)
0.3 6.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.3 23.6 GO:0031526 brush border membrane(GO:0031526)
0.3 4.0 GO:0017119 Golgi transport complex(GO:0017119)
0.3 21.6 GO:0045095 keratin filament(GO:0045095)
0.3 5.1 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.3 23.4 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.3 0.8 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.3 8.1 GO:0000795 synaptonemal complex(GO:0000795)
0.3 4.4 GO:0045120 pronucleus(GO:0045120)
0.3 1.6 GO:0036157 outer dynein arm(GO:0036157)
0.3 1.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.3 2.3 GO:0070187 telosome(GO:0070187)
0.3 4.1 GO:0032039 integrator complex(GO:0032039)
0.3 3.3 GO:0000124 SAGA complex(GO:0000124)
0.3 4.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.3 0.8 GO:0044307 dendritic branch(GO:0044307)
0.3 2.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 3.2 GO:0016580 Sin3 complex(GO:0016580)
0.2 1.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 0.9 GO:0000322 storage vacuole(GO:0000322)
0.2 7.4 GO:0000791 euchromatin(GO:0000791)
0.2 3.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 1.0 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.2 1.9 GO:0070652 HAUS complex(GO:0070652)
0.2 1.2 GO:0097422 tubular endosome(GO:0097422)
0.2 1.2 GO:0043203 axon hillock(GO:0043203)
0.2 0.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.2 0.8 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 63.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.2 197.0 GO:0005739 mitochondrion(GO:0005739)
0.2 1.6 GO:0030891 VCB complex(GO:0030891)
0.2 3.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 2.0 GO:0032426 stereocilium tip(GO:0032426)
0.2 3.8 GO:0097546 ciliary base(GO:0097546)
0.2 2.0 GO:0035253 ciliary rootlet(GO:0035253)
0.2 2.9 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.6 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.9 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 4.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.2 GO:0005775 vacuolar lumen(GO:0005775)
0.1 2.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 1.0 GO:0032009 early phagosome(GO:0032009)
0.1 2.8 GO:0005902 microvillus(GO:0005902)
0.1 5.7 GO:0005903 brush border(GO:0005903)
0.1 0.5 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 1.4 GO:0036038 MKS complex(GO:0036038)
0.1 0.5 GO:0031597 nuclear proteasome complex(GO:0031595) cytosolic proteasome complex(GO:0031597)
0.1 0.5 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.8 GO:0042555 MCM complex(GO:0042555)
0.1 0.3 GO:0035363 histone locus body(GO:0035363)
0.1 62.1 GO:0005615 extracellular space(GO:0005615)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.3 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
50.1 150.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
26.4 79.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
24.5 98.2 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
19.5 97.3 GO:0019862 IgA binding(GO:0019862)
19.2 96.2 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
17.4 69.7 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
16.1 80.4 GO:0016841 ammonia-lyase activity(GO:0016841)
14.1 42.4 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
12.7 38.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
12.0 35.9 GO:0031714 C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
11.4 68.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
11.4 319.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
10.6 74.2 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
10.2 30.6 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
9.7 58.3 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
9.6 38.5 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
9.4 37.5 GO:0047619 acylcarnitine hydrolase activity(GO:0047619)
8.9 26.8 GO:0015203 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
8.9 35.4 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
8.8 35.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
8.8 26.4 GO:0032810 sterol response element binding(GO:0032810)
8.4 33.5 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
8.3 24.9 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
8.2 32.7 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973)
8.1 40.7 GO:0005534 galactose binding(GO:0005534)
8.0 32.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
7.8 62.3 GO:0008430 selenium binding(GO:0008430)
7.7 23.0 GO:0004925 prolactin receptor activity(GO:0004925)
7.3 29.3 GO:0002058 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061)
7.2 36.1 GO:0070404 NADH binding(GO:0070404)
7.2 136.1 GO:0001848 complement binding(GO:0001848)
7.2 21.5 GO:0004359 glutaminase activity(GO:0004359)
7.0 21.0 GO:0004657 proline dehydrogenase activity(GO:0004657)
6.9 20.6 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
6.7 66.9 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
6.7 13.4 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
6.5 52.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
6.5 58.5 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
6.5 25.9 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
6.3 38.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
6.3 69.6 GO:0039706 co-receptor binding(GO:0039706)
6.3 125.5 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
6.3 194.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
6.0 24.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
6.0 24.1 GO:0004771 sterol esterase activity(GO:0004771)
5.8 29.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
5.8 40.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
5.8 51.9 GO:0015232 heme transporter activity(GO:0015232)
5.7 34.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
5.7 17.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
5.6 33.8 GO:0042954 lipoprotein transporter activity(GO:0042954)
5.6 28.1 GO:0005550 pheromone binding(GO:0005550)
5.5 44.3 GO:0003996 acyl-CoA ligase activity(GO:0003996)
5.5 21.8 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
5.4 37.9 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
5.2 51.8 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
4.9 19.6 GO:0004903 growth hormone receptor activity(GO:0004903)
4.8 14.3 GO:0030156 benzodiazepine receptor binding(GO:0030156)
4.6 13.8 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
4.6 36.7 GO:0008172 S-methyltransferase activity(GO:0008172)
4.5 18.2 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
4.5 27.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
4.4 97.0 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
4.4 22.0 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
4.3 13.0 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
4.3 13.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
4.3 168.0 GO:0004364 glutathione transferase activity(GO:0004364)
4.2 38.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
4.2 16.7 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
4.1 12.3 GO:0004655 porphobilinogen synthase activity(GO:0004655)
4.1 20.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
4.0 40.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
4.0 24.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
4.0 12.0 GO:0004167 dopachrome isomerase activity(GO:0004167)
3.9 19.6 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
3.9 27.1 GO:0032052 bile acid binding(GO:0032052)
3.8 15.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
3.7 14.8 GO:0008265 Mo-molybdopterin cofactor sulfurase activity(GO:0008265)
3.7 11.0 GO:2001070 starch binding(GO:2001070)
3.6 14.5 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
3.6 10.8 GO:0051990 (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
3.5 10.5 GO:0015254 glycerol channel activity(GO:0015254)
3.5 41.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
3.5 20.8 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
3.4 10.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
3.3 40.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
3.3 9.9 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
3.3 22.9 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
3.2 9.7 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
3.2 25.9 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
3.2 25.6 GO:0070053 thrombospondin receptor activity(GO:0070053)
3.1 12.6 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
3.1 12.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
3.1 12.5 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
3.0 18.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
3.0 24.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
3.0 342.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
3.0 11.8 GO:0045134 uridine-diphosphatase activity(GO:0045134)
2.9 8.7 GO:0035800 deubiquitinase activator activity(GO:0035800)
2.8 16.5 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
2.7 22.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
2.7 5.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
2.7 8.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
2.6 5.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
2.6 13.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
2.6 7.8 GO:0004736 pyruvate carboxylase activity(GO:0004736)
2.6 33.6 GO:0016208 AMP binding(GO:0016208)
2.6 20.5 GO:0047134 protein-disulfide reductase activity(GO:0047134)
2.6 33.2 GO:0017127 cholesterol transporter activity(GO:0017127)
2.5 15.2 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
2.5 94.9 GO:0016831 carboxy-lyase activity(GO:0016831)
2.5 59.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
2.5 7.4 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
2.5 7.4 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
2.4 12.1 GO:0001155 TFIIIA-class transcription factor binding(GO:0001155)
2.4 21.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
2.3 44.5 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
2.3 11.7 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
2.3 9.1 GO:0034584 piRNA binding(GO:0034584)
2.3 9.0 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
2.2 6.7 GO:0070735 protein-glycine ligase activity(GO:0070735)
2.2 22.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
2.2 66.8 GO:0004623 phospholipase A2 activity(GO:0004623)
2.2 13.3 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
2.2 8.8 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
2.2 8.6 GO:0050682 AF-2 domain binding(GO:0050682)
2.1 14.6 GO:0035375 zymogen binding(GO:0035375)
2.0 22.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
2.0 11.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
1.9 13.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
1.8 27.4 GO:0034185 apolipoprotein binding(GO:0034185)
1.8 7.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
1.8 14.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
1.8 372.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
1.7 8.7 GO:0031849 olfactory receptor binding(GO:0031849)
1.7 5.2 GO:0030977 taurine binding(GO:0030977)
1.7 5.2 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
1.7 6.7 GO:0005136 interleukin-4 receptor binding(GO:0005136)
1.6 40.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
1.6 9.7 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
1.6 6.3 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
1.6 6.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
1.6 20.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
1.6 3.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
1.6 15.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
1.5 7.7 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
1.5 9.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
1.5 12.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
1.5 4.6 GO:0042903 tubulin deacetylase activity(GO:0042903)
1.4 4.3 GO:0003922 GMP synthase activity(GO:0003921) GMP synthase (glutamine-hydrolyzing) activity(GO:0003922)
1.4 5.7 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
1.4 8.6 GO:0030881 beta-2-microglobulin binding(GO:0030881)
1.4 8.6 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
1.4 7.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.4 19.9 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
1.4 7.1 GO:0005148 prolactin receptor binding(GO:0005148)
1.4 8.5 GO:0031404 chloride ion binding(GO:0031404)
1.4 7.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
1.4 5.6 GO:0042731 PH domain binding(GO:0042731)
1.4 4.2 GO:0047708 biotinidase activity(GO:0047708)
1.4 11.0 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
1.4 6.9 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.4 8.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
1.4 6.9 GO:0015204 urea transmembrane transporter activity(GO:0015204)
1.4 4.1 GO:0004827 proline-tRNA ligase activity(GO:0004827)
1.4 67.9 GO:0038024 cargo receptor activity(GO:0038024)
1.4 4.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
1.3 4.0 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
1.3 34.4 GO:0004016 adenylate cyclase activity(GO:0004016)
1.3 10.5 GO:0051525 NFAT protein binding(GO:0051525)
1.3 14.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
1.3 9.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
1.3 3.9 GO:0009384 N-acylmannosamine kinase activity(GO:0009384)
1.3 5.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
1.3 6.3 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
1.3 5.0 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
1.3 7.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
1.3 21.3 GO:0005537 mannose binding(GO:0005537)
1.2 5.0 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
1.2 8.7 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
1.2 8.6 GO:0034711 inhibin binding(GO:0034711)
1.2 10.8 GO:0060229 lipase activator activity(GO:0060229)
1.2 4.8 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829)
1.2 3.6 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
1.2 4.7 GO:0070568 guanylyltransferase activity(GO:0070568)
1.1 11.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
1.1 7.7 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
1.1 14.0 GO:0004806 triglyceride lipase activity(GO:0004806)
1.1 6.4 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
1.1 28.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
1.1 5.3 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
1.1 8.5 GO:0016885 CoA carboxylase activity(GO:0016421) ligase activity, forming carbon-carbon bonds(GO:0016885)
1.1 5.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.0 5.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
1.0 4.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
1.0 3.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
1.0 5.0 GO:0071723 lipopeptide binding(GO:0071723)
1.0 4.0 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
1.0 3.0 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
1.0 3.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
1.0 14.8 GO:0016854 racemase and epimerase activity(GO:0016854)
1.0 102.0 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.9 3.8 GO:0032557 pyrimidine ribonucleotide binding(GO:0032557)
0.9 3.8 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.9 2.8 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.9 2.7 GO:0015350 methotrexate transporter activity(GO:0015350)
0.9 2.7 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.9 2.7 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.9 3.5 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.9 3.5 GO:0048019 receptor antagonist activity(GO:0048019)
0.9 4.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.9 3.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.8 67.4 GO:0051087 chaperone binding(GO:0051087)
0.8 6.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.8 11.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.8 3.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.8 2.4 GO:0017042 glycosylceramidase activity(GO:0017042)
0.8 13.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.8 2.3 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.8 9.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.8 6.9 GO:0008494 translation activator activity(GO:0008494)
0.8 16.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.7 8.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.7 2.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.7 2.1 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.7 2.7 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.7 9.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.7 7.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.7 51.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.7 2.0 GO:0031765 galanin receptor binding(GO:0031763) type 2 galanin receptor binding(GO:0031765) type 3 galanin receptor binding(GO:0031766)
0.7 16.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.7 6.7 GO:0008242 omega peptidase activity(GO:0008242)
0.7 3.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.7 2.0 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.6 5.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.6 8.4 GO:0003796 lysozyme activity(GO:0003796)
0.6 5.8 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.6 5.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.6 3.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.6 98.7 GO:0008083 growth factor activity(GO:0008083)
0.6 11.2 GO:0008199 ferric iron binding(GO:0008199)
0.6 5.6 GO:0070402 NADPH binding(GO:0070402)
0.6 6.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.6 3.0 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.6 3.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.6 1.2 GO:0042806 fucose binding(GO:0042806)
0.6 9.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.6 4.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.6 15.7 GO:0042165 neurotransmitter binding(GO:0042165)
0.6 2.3 GO:0043295 glutathione binding(GO:0043295)
0.6 5.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.6 5.0 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.5 2.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.5 4.9 GO:0009881 photoreceptor activity(GO:0009881)
0.5 2.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.5 2.2 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.5 12.9 GO:0008527 taste receptor activity(GO:0008527)
0.5 2.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.5 7.8 GO:0004697 protein kinase C activity(GO:0004697)
0.5 1.5 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.5 1.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.5 2.5 GO:0045340 mercury ion binding(GO:0045340)
0.5 4.9 GO:0051787 misfolded protein binding(GO:0051787)
0.5 2.3 GO:0031419 cobalamin binding(GO:0031419)
0.5 1.4 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.5 5.9 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.4 4.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.4 1.3 GO:0019807 aspartoacylase activity(GO:0019807)
0.4 3.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.4 1.3 GO:0004774 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.4 6.5 GO:0035497 cAMP response element binding(GO:0035497)
0.4 4.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.4 11.1 GO:0070001 aspartic-type peptidase activity(GO:0070001)
0.4 4.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.4 1.7 GO:0008940 nitrate reductase activity(GO:0008940)
0.4 4.6 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.4 1.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.4 6.9 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.4 4.0 GO:0015926 glucosidase activity(GO:0015926)
0.4 2.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.4 3.9 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.4 1.5 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.4 3.4 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.4 1.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704) IkappaB kinase activity(GO:0008384)
0.4 2.5 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.4 4.3 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.4 3.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.4 5.4 GO:0008143 poly(A) binding(GO:0008143)
0.4 5.7 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.4 2.8 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.3 2.1 GO:0030911 TPR domain binding(GO:0030911)
0.3 4.0 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.3 3.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.3 1.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.3 1.3 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.3 1.9 GO:0031013 troponin I binding(GO:0031013)
0.3 3.7 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.3 12.1 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.3 0.9 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846) diacylglycerol O-acyltransferase activity(GO:0004144)
0.3 2.7 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.3 3.0 GO:0051766 inositol trisphosphate kinase activity(GO:0051766)
0.3 2.3 GO:0030957 Tat protein binding(GO:0030957)
0.3 1.1 GO:0016492 G-protein coupled neurotensin receptor activity(GO:0016492)
0.3 1.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.3 1.4 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.3 1.4 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.3 1.4 GO:0001601 peptide YY receptor activity(GO:0001601)
0.3 2.4 GO:0019808 polyamine binding(GO:0019808)
0.3 2.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3 1.6 GO:0009378 four-way junction helicase activity(GO:0009378)
0.3 3.6 GO:0005243 gap junction channel activity(GO:0005243)
0.2 5.0 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.2 2.4 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 1.9 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.2 1.4 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.2 26.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 2.0 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.2 3.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2 4.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.2 4.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 11.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 5.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 7.4 GO:0042605 peptide antigen binding(GO:0042605)
0.2 5.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 2.1 GO:0001972 retinoic acid binding(GO:0001972)
0.2 1.2 GO:0050693 LBD domain binding(GO:0050693)
0.2 1.0 GO:0050785 advanced glycation end-product receptor activity(GO:0050785)
0.2 1.2 GO:0034452 dynactin binding(GO:0034452)
0.2 4.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 1.0 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 1.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 2.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 1.3 GO:0003896 DNA primase activity(GO:0003896)
0.2 0.9 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 1.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 1.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 2.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.2 0.7 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.2 1.0 GO:0046915 transition metal ion transmembrane transporter activity(GO:0046915)
0.2 69.7 GO:0005549 odorant binding(GO:0005549)
0.2 3.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 0.9 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.2 0.5 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 0.6 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 2.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 1.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.8 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 5.0 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 0.8 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.3 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.3 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 2.6 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.1 0.4 GO:0005047 signal recognition particle binding(GO:0005047) endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.2 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 1.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 78.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.8 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.2 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.7 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.9 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 2.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 1.4 GO:0051213 dioxygenase activity(GO:0051213)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0015923 alpha-mannosidase activity(GO:0004559) mannosidase activity(GO:0015923)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 1.5 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.1 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 2.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.5 GO:0008146 sulfotransferase activity(GO:0008146)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 137.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
2.5 593.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
2.3 122.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
1.8 20.2 ST JAK STAT PATHWAY Jak-STAT Pathway
1.3 48.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.9 39.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.8 14.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.7 2.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.6 10.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.6 0.6 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.6 11.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.6 20.0 PID CD40 PATHWAY CD40/CD40L signaling
0.5 14.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.5 2.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.5 16.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.5 9.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.5 2.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.5 20.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.4 12.9 PID IL1 PATHWAY IL1-mediated signaling events
0.4 15.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.4 16.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.4 5.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.4 5.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.4 9.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.4 14.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.3 13.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.3 1.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.3 6.8 PID IL23 PATHWAY IL23-mediated signaling events
0.3 7.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.3 11.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 12.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.2 2.0 PID IL3 PATHWAY IL3-mediated signaling events
0.2 2.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.2 1.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 7.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 1.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 13.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 0.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 3.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
17.5 296.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
12.5 200.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
9.5 28.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
8.5 127.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
8.5 110.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
8.2 156.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
8.1 169.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
7.7 23.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
5.1 45.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
4.9 39.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
4.7 61.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
4.7 28.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
4.4 127.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
4.2 38.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
3.7 98.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
3.6 29.0 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
3.0 27.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
2.9 52.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
2.9 34.7 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
2.8 16.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
2.6 37.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
2.2 367.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
2.2 64.0 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
2.1 45.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
2.0 12.2 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
2.0 48.7 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
1.8 29.9 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
1.8 35.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.6 38.9 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
1.5 25.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
1.5 41.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
1.4 15.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
1.3 22.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
1.3 18.0 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
1.1 13.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
1.1 46.0 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
1.1 8.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
1.1 22.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
1.1 80.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
1.1 20.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
1.0 14.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
1.0 33.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
1.0 5.0 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
1.0 10.9 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.9 15.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.9 8.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.9 19.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.8 17.2 REACTOME BIOLOGICAL OXIDATIONS Genes involved in Biological oxidations
0.8 23.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.8 15.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.8 9.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.8 26.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.7 1.5 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.7 17.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.7 83.3 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.7 7.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.7 15.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.6 4.9 REACTOME OPSINS Genes involved in Opsins
0.6 6.4 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.6 7.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.5 19.5 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.5 1.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.5 6.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.5 5.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.5 8.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.5 8.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.5 6.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.5 2.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.4 24.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.4 1.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.4 5.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.4 6.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.4 2.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.4 2.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.4 2.5 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.3 2.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.3 6.1 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.3 3.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.3 6.0 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.3 1.8 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.2 15.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 3.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 6.1 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.2 5.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 4.6 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.2 4.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2 3.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 4.5 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.1 5.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 3.2 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.1 0.8 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 3.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 2.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.5 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 1.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 1.2 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.1 0.6 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling