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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Nkx3-2

Z-value: 1.38

Motif logo

Transcription factors associated with Nkx3-2

Gene Symbol Gene ID Gene Info
ENSRNOG00000060782 NK3 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx3-2rn6_v1_chr14_+_73813528_73813528-0.393.7e-13Click!

Activity profile of Nkx3-2 motif

Sorted Z-values of Nkx3-2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_45561390 45.99 ENSRNOT00000047820

chr2_-_200762492 35.94 ENSRNOT00000056172
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr2_-_200762206 35.37 ENSRNOT00000068511
ENSRNOT00000086835
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr5_+_115649046 35.08 ENSRNOT00000041328
glyceraldehyde-3-phosphate dehydrogenase
chr5_-_138222534 34.64 ENSRNOT00000009691
zinc finger protein 691
chr1_-_220136470 33.92 ENSRNOT00000026812
actinin alpha 3
chr17_+_32082937 32.67 ENSRNOT00000074775
myosin light chain kinase family, member 4
chr4_+_62019970 32.20 ENSRNOT00000013133
aldose reductase-related protein 1-like
chr16_+_25773602 31.70 ENSRNOT00000047750
glyceraldehyde-3-phosphate dehydrogenase, pseudogene 2
chr11_-_72109964 29.99 ENSRNOT00000058917

chr5_+_164808323 29.02 ENSRNOT00000011005
natriuretic peptide A
chr3_+_132052612 28.88 ENSRNOT00000030148

chr18_-_63825408 28.40 ENSRNOT00000043709
similar to glyceraldehyde-3-phosphate dehydrogenase
chr13_-_111765944 28.16 ENSRNOT00000073041
synaptotagmin 14
chr16_-_49574314 25.68 ENSRNOT00000017568
ENSRNOT00000085535
ENSRNOT00000017054
PDZ and LIM domain 3
chr12_+_28381982 25.48 ENSRNOT00000076101
Williams-Beuren syndrome chromosome region 17
chr8_+_100260049 25.40 ENSRNOT00000011090

chr2_+_226825635 25.37 ENSRNOT00000042173

chr16_+_16949232 24.45 ENSRNOT00000047499

chr10_-_56558487 24.43 ENSRNOT00000023256
solute carrier family 2 member 4
chr8_-_120446455 24.13 ENSRNOT00000085161
ENSRNOT00000042854
ENSRNOT00000037199
cAMP regulated phosphoprotein 21
chr3_+_55910177 23.51 ENSRNOT00000009969
kelch-like family member 41
chr5_-_17061837 23.39 ENSRNOT00000011892
proenkephalin
chr13_-_103080920 23.17 ENSRNOT00000034990

chr11_+_70687500 22.88 ENSRNOT00000037432

chr5_+_90338795 22.53 ENSRNOT00000077864
ENSRNOT00000058882
similar to RIKEN cDNA 2310003M01
chr18_+_79406381 21.85 ENSRNOT00000022303
ENSRNOT00000058295
ENSRNOT00000058296
ENSRNOT00000022280
myelin basic protein
chr5_-_17061361 21.15 ENSRNOT00000089318
proenkephalin
chr20_+_44060731 19.92 ENSRNOT00000000737
laminin subunit alpha 4
chr2_-_22385676 19.85 ENSRNOT00000065224
thrombospondin 4
chr7_-_119158173 19.78 ENSRNOT00000067483
ENSRNOT00000078528
thioredoxin 2
chr1_-_282251257 19.15 ENSRNOT00000015186
peroxiredoxin 3
chr3_+_57770948 18.83 ENSRNOT00000038429

chr12_-_22472044 18.73 ENSRNOT00000073356
UFM1-specific peptidase 1
chr11_-_75144903 18.48 ENSRNOT00000002329
HRAS-like suppressor
chrX_-_37353156 18.25 ENSRNOT00000086120

chrX_-_66602458 17.91 ENSRNOT00000076510
ENSRNOT00000017429
ectodysplasin A2 receptor
chr2_-_200625434 17.87 ENSRNOT00000079754
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5
chr18_+_31396922 17.70 ENSRNOT00000026273
SEL1 domain containing protein RGD735029
chr8_-_109576353 16.77 ENSRNOT00000010320
protein phosphatase 2, regulatory subunit B'', alpha
chr1_+_199351628 16.67 ENSRNOT00000078578
branched chain ketoacid dehydrogenase kinase
chr3_+_40038336 16.51 ENSRNOT00000048804
polypeptide N-acetylgalactosaminyltransferase 13
chr7_+_116632506 15.41 ENSRNOT00000009811
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chrX_+_25016401 15.36 ENSRNOT00000059270
chloride voltage-gated channel 4
chr10_-_84698886 15.04 ENSRNOT00000067542
nuclear factor, erythroid 2-like 1
chr1_-_189960073 14.91 ENSRNOT00000088482
crystallin, mu
chr9_-_89195273 14.42 ENSRNOT00000022281
SPHK1 interactor, AKAP domain containing
chr5_-_25583834 13.83 ENSRNOT00000067823
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr5_+_70441123 13.67 ENSRNOT00000087517
fibronectin type III and SPRY domain containing 1-like
chr2_+_248398917 13.35 ENSRNOT00000045855
guanylate binding protein 1
chr6_+_27589657 13.22 ENSRNOT00000038649
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
chr4_+_129574264 13.19 ENSRNOT00000010185
ADP-ribosylation factor like GTPase 6 interacting protein 5
chr4_+_115713004 13.17 ENSRNOT00000064536
dysferlin
chr4_+_115712850 12.93 ENSRNOT00000085765
dysferlin
chr10_-_102289837 12.64 ENSRNOT00000044922

chr2_+_166140112 12.30 ENSRNOT00000074564
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr3_-_111469518 12.09 ENSRNOT00000006874
NADH:ubiquinone oxidoreductase complex assembly factor 1
chr4_+_14039977 11.96 ENSRNOT00000091249
ENSRNOT00000075878
CD36 molecule
chr6_-_55647665 11.90 ENSRNOT00000007414
basic leucine zipper and W2 domains 2
chr12_-_13924531 11.82 ENSRNOT00000001477
solute carrier family 29 member 4
chr14_-_37770059 11.82 ENSRNOT00000029721
solute carrier family 10, member 4
chrX_+_109940350 11.75 ENSRNOT00000093543
ENSRNOT00000057049
Nik related kinase
chr2_+_143656793 11.73 ENSRNOT00000084527
ENSRNOT00000017453
periostin
chr16_+_81665540 10.92 ENSRNOT00000026546
ENSRNOT00000092644
ENSRNOT00000073240
growth hormone regulated TBC protein 1
chr12_+_38377034 10.90 ENSRNOT00000088002
CAP-GLY domain containing linker protein 1
chr13_+_90514336 10.42 ENSRNOT00000088996
ENSRNOT00000085377
peroxisomal biogenesis factor 19
chr1_+_80777014 10.22 ENSRNOT00000079758
predicted gene, 19345
chr8_+_44136496 10.21 ENSRNOT00000087022
sodium voltage-gated channel beta subunit 3
chr17_-_90071408 9.89 ENSRNOT00000071978
decaprenyl diphosphate synthase subunit 1
chr5_-_164747083 9.83 ENSRNOT00000010433
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr10_-_29196563 9.64 ENSRNOT00000005205
fatty acid binding protein 6
chr13_+_82355471 9.50 ENSRNOT00000030677
selectin E
chr2_+_266315036 9.47 ENSRNOT00000055245
wntless Wnt ligand secretion mediator
chr8_+_62723788 9.21 ENSRNOT00000010620
semaphorin 7A (John Milton Hagen blood group)
chr13_+_56262190 9.18 ENSRNOT00000032908

chr10_-_69537882 9.18 ENSRNOT00000031360
C-C motif chemokine ligand 1
chr10_-_89918427 9.11 ENSRNOT00000084217
dual specificity phosphatase 3
chr18_+_14756684 9.01 ENSRNOT00000076085
ENSRNOT00000076129
microtubule-associated protein, RP/EB family, member 2
chr1_+_42121636 8.97 ENSRNOT00000025616
myc target 1
chr2_-_171196395 8.45 ENSRNOT00000013279
butyrylcholinesterase
chr2_+_151314818 8.43 ENSRNOT00000019305
purinergic receptor P2Y1
chr10_-_29196252 8.34 ENSRNOT00000083910
fatty acid binding protein 6
chr5_-_166430254 8.26 ENSRNOT00000048914
nicotinamide nucleotide adenylyltransferase 1
chr13_-_78885464 8.15 ENSRNOT00000003828
aspartyl-tRNA synthetase 2 (mitochondrial)
chr8_-_109418872 8.15 ENSRNOT00000021657
propionyl-CoA carboxylase beta subunit
chrX_+_105500173 8.08 ENSRNOT00000040476
armadillo repeat containing, X-linked 4
chr10_+_110138586 8.03 ENSRNOT00000086096
solute carrier family 16 member 3
chr7_-_120672350 7.99 ENSRNOT00000018126
ENSRNOT00000087800
ENSRNOT00000088424
casein kinase 1, epsilon
chr10_-_78690857 7.96 ENSRNOT00000089255
similar to glyceraldehyde-3-phosphate dehydrogenase
chr1_+_89491654 7.93 ENSRNOT00000028632
leucine-rich repeat LGI family, member 4
chr2_+_187512164 7.78 ENSRNOT00000051394
myocyte enhancer factor 2D
chr19_+_57047830 7.76 ENSRNOT00000080860
polypeptide N-acetylgalactosaminyltransferase 2
chr2_+_66940057 7.73 ENSRNOT00000043050
cadherin 9
chr19_-_1074333 7.65 ENSRNOT00000017983
ENSRNOT00000086995
cadherin 5
chr6_+_108167716 7.59 ENSRNOT00000064426
lin-52 DREAM MuvB core complex component
chr13_+_82355886 7.55 ENSRNOT00000076757
selectin E
chr1_-_755645 7.50 ENSRNOT00000073546
vomeronasal 2 receptor, 6
chr8_-_83693472 7.43 ENSRNOT00000015947
family with sequence similarity 83, member B
chr9_+_62291405 7.42 ENSRNOT00000051463
phospholipase C-like 1
chr20_-_4390436 7.42 ENSRNOT00000000497
ENSRNOT00000077655
palmitoyl-protein thioesterase 2
chr10_-_36419926 7.30 ENSRNOT00000004902
zinc finger protein 354B
chr12_-_23624212 7.28 ENSRNOT00000064405
ENSRNOT00000001943
RAS p21 protein activator 4
chr2_-_189903219 7.18 ENSRNOT00000017000
S100 calcium binding protein A1
chr2_-_147693082 7.15 ENSRNOT00000022507
WW domain containing transcription regulator 1
chr17_-_21577631 7.07 ENSRNOT00000066371
transmembrane protein 14C
chr12_+_40018937 7.00 ENSRNOT00000001697
cut-like homeobox 2
chr10_+_88326080 6.96 ENSRNOT00000076475
FK506 binding protein 10
chr8_-_90664554 6.76 ENSRNOT00000039917
ENSRNOT00000074896
ENSRNOT00000072225
high mobility group nucleosomal binding domain 3
chr4_+_109467272 6.75 ENSRNOT00000008212
regenerating family member 3 beta
chrX_-_74968405 6.73 ENSRNOT00000035653
similar to KIAA2022 protein
chr9_+_73528681 6.62 ENSRNOT00000084340
unc-80 homolog, NALCN activator
chr5_+_140870140 6.38 ENSRNOT00000074347
hippocalcin-like 4
chr17_-_84249243 6.12 ENSRNOT00000082549
nebulette
chr1_-_64030175 6.11 ENSRNOT00000089950
tRNA splicing endonuclease subunit 34-like 1
chr1_+_240908483 6.07 ENSRNOT00000019367
Kruppel-like factor 9
chr7_+_38897278 6.07 ENSRNOT00000006450
epiphycan
chr11_-_81717521 6.05 ENSRNOT00000058422
alpha-2-HS-glycoprotein
chr11_-_87081950 6.00 ENSRNOT00000002574
DiGeorge syndrome critical region gene 6
chr3_-_175426395 5.62 ENSRNOT00000082686
proteasome subunit alpha 7
chr16_-_21089508 5.61 ENSRNOT00000072565
hyaluronan and proteoglycan link protein 4
chr10_+_88326337 5.56 ENSRNOT00000022029
ENSRNOT00000076461
FK506 binding protein 10
chr10_+_85646633 5.53 ENSRNOT00000086608
proteasome subunit beta 3
chr1_+_699413 5.44 ENSRNOT00000072360

chr19_+_45938915 5.40 ENSRNOT00000065508
MON1 homolog B, secretory trafficking associated
chr1_-_67065797 5.38 ENSRNOT00000048152
vomeronasal 1 receptor 46
chr1_-_172943853 5.34 ENSRNOT00000047040
olfactory receptor 278
chr10_-_27862868 5.30 ENSRNOT00000004877
gamma-aminobutyric acid type A receptor alpha 6 subunit
chr3_+_114253637 5.30 ENSRNOT00000046843
dual oxidase 1
chr9_+_62291809 5.24 ENSRNOT00000090621
phospholipase C-like 1
chr18_+_30574627 5.13 ENSRNOT00000060484
protocadherin beta 19
chr7_+_123168811 5.09 ENSRNOT00000007091
cold shock domain containing C2
chr14_-_115352562 5.06 ENSRNOT00000050321
endoplasmic reticulum lectin 1
chr10_-_34333305 4.96 ENSRNOT00000071365
olfactory receptor gene Olr1384
chr8_-_107819050 4.93 ENSRNOT00000019536
armadillo repeat containing 8
chr3_+_20993205 4.85 ENSRNOT00000010465
olfactory receptor 419
chr10_-_88533829 4.83 ENSRNOT00000080521
DnaJ heat shock protein family (Hsp40) member C7
chr11_+_75434197 4.82 ENSRNOT00000032569
Mab-21 domain containing 2
chr3_+_147358858 4.82 ENSRNOT00000012951
R-spondin 4
chr3_+_72460889 4.77 ENSRNOT00000012209
tankyrase 1 binding protein 1
chr19_+_56243408 4.74 ENSRNOT00000000281
differentially expressed in FDCP 8 homolog
chr9_-_86103158 4.61 ENSRNOT00000021528
cullin 3
chr8_-_117820413 4.61 ENSRNOT00000075819
translation machinery associated 7 homolog
chr1_-_63457134 4.57 ENSRNOT00000083436

chr15_+_23792931 4.54 ENSRNOT00000092091
sterile alpha motif domain containing 4A
chrX_+_158835811 4.49 ENSRNOT00000071888
ENSRNOT00000080110
integrator complex subunit 6 like
chr1_-_168611670 4.45 ENSRNOT00000021273
olfactory receptor 106
chr9_-_10710648 4.40 ENSRNOT00000089374
lysine demethylase 4B
chr10_-_103816287 4.30 ENSRNOT00000004477
glutamate ionotropic receptor NMDA type subunit 2C
chr14_+_109533792 4.27 ENSRNOT00000067690
ankyrin repeat domain-containing protein 29-like
chr7_+_59326518 4.10 ENSRNOT00000085231
protein tyrosine phosphatase, receptor type, B
chr8_+_21305250 4.10 ENSRNOT00000050206
olfactory receptor 1193
chr12_+_12374790 4.08 ENSRNOT00000001347
tectonin beta-propeller repeat containing 1
chr3_-_105470475 4.03 ENSRNOT00000011078
gap junction protein, delta 2
chr1_-_71135764 4.03 ENSRNOT00000064949
small integral membrane protein 17
chr17_-_33951484 4.00 ENSRNOT00000023957
forkhead box C1
chr3_+_2512492 3.96 ENSRNOT00000074026

chr13_-_89565813 3.92 ENSRNOT00000004347
Purkinje cell protein 4-like 1
chr10_-_1744647 3.86 ENSRNOT00000081886

chrX_-_123662350 3.83 ENSRNOT00000092624
septin 6
chr10_-_74298599 3.81 ENSRNOT00000007379
yippee-like 2
chr3_+_20878701 3.79 ENSRNOT00000046877
olfactory receptor 413
chr1_+_226742795 3.78 ENSRNOT00000084270
VPS37C, ESCRT-I subunit
chr12_-_52396066 3.78 ENSRNOT00000056712
leucine rich colipase-like 1
chr8_-_21341431 3.75 ENSRNOT00000044249
olfactory receptor 1192
chr13_-_72063347 3.73 ENSRNOT00000090544
ENSRNOT00000003869
calcium voltage-gated channel subunit alpha1 E
chr14_+_216098 3.71 ENSRNOT00000033032
vomeronasal 2 receptor, 65
chr8_+_117648745 3.66 ENSRNOT00000027762
solute carrier family 26 member 6
chr20_-_4391402 3.62 ENSRNOT00000090518
ENSRNOT00000083489
palmitoyl-protein thioesterase 2
chr5_+_79367663 3.55 ENSRNOT00000011508
ATPase H+ transporting V1 subunit G1
chr10_-_34361212 3.52 ENSRNOT00000072557
olfactory receptor 1385
chrX_+_73390903 3.48 ENSRNOT00000077002
zinc finger protein 449
chr7_+_98432024 3.48 ENSRNOT00000091077
fer-1-like family member 6
chr1_+_113034227 3.46 ENSRNOT00000081831
ENSRNOT00000077877
ENSRNOT00000077594
gamma-aminobutyric acid type A receptor beta 3 subunit
chr1_+_67025240 3.43 ENSRNOT00000051024
vomeronasal 1 receptor 47
chr2_+_58462949 3.43 ENSRNOT00000080618
NAD kinase 2, mitochondrial
chr7_-_24667301 3.39 ENSRNOT00000009154
transmembrane protein 263
chr16_-_64745207 3.39 ENSRNOT00000032467
TELO2 interacting protein 2
chr10_+_94207336 3.37 ENSRNOT00000010816
potassium voltage-gated channel subfamily H member 6
chr18_+_30509393 3.29 ENSRNOT00000043846
protocadherin beta 12
chr1_-_261446570 3.24 ENSRNOT00000020182
secreted frizzled-related protein 5
chr3_+_16241573 3.20 ENSRNOT00000082831
olfactory receptor 407
chr10_-_88533171 3.13 ENSRNOT00000024321
DnaJ heat shock protein family (Hsp40) member C7
chr6_+_55085313 3.12 ENSRNOT00000005458

chr1_-_67206713 3.10 ENSRNOT00000048195
vomeronasal 1 receptor 43
chr8_-_20173107 3.08 ENSRNOT00000045215
olfactory receptor 1163
chr3_+_79729739 3.07 ENSRNOT00000084833
kelch repeat and BTB domain containing 4
chr1_-_196884302 3.07 ENSRNOT00000089464
NSE1 homolog, SMC5-SMC6 complex component
chr10_+_111770168 3.03 ENSRNOT00000074598
vomeronasal 2 receptor, 65
chr3_-_76289390 3.01 ENSRNOT00000051968
olfactory receptor 609
chr3_+_118317761 2.99 ENSRNOT00000012700
fibroblast growth factor 7
chr10_+_112056994 2.96 ENSRNOT00000073032
vomeronasal 2 receptor, 65
chr15_+_42522108 2.95 ENSRNOT00000021621
coiled-coil domain containing 25
chr8_-_18762922 2.89 ENSRNOT00000008423
olfactory receptor 1122
chr10_-_44471915 2.83 ENSRNOT00000089901
olfactory receptor 1440
chr6_-_67084234 2.83 ENSRNOT00000050372
NOVA alternative splicing regulator 1
chr9_+_23596964 2.79 ENSRNOT00000064279
exocrine gland-secreted peptide 1-like
chr10_-_66020682 2.79 ENSRNOT00000011019
family with sequence similarity 58, member B
chr19_-_55490426 2.79 ENSRNOT00000081800
CBFA2/RUNX1 translocation partner 3
chr19_-_10653800 2.72 ENSRNOT00000022128
C-X3-C motif chemokine ligand 1
chr9_+_70450444 2.71 ENSRNOT00000002872
FAST kinase domains 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx3-2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
14.8 44.5 GO:0051867 general adaptation syndrome, behavioral process(GO:0051867)
11.9 71.3 GO:0034757 negative regulation of iron ion transport(GO:0034757)
11.7 35.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
11.3 33.9 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) positive regulation of purine nucleotide catabolic process(GO:0033123)
11.2 33.6 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
9.7 29.0 GO:1902304 positive regulation of potassium ion export(GO:1902304)
6.1 6.1 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
5.6 16.8 GO:0090247 cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
5.1 15.4 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
4.0 19.8 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
3.8 19.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
3.3 9.8 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
3.2 9.5 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
2.9 8.7 GO:0014016 neuroblast differentiation(GO:0014016)
2.8 8.3 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
2.7 8.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
2.6 13.2 GO:0002036 regulation of L-glutamate transport(GO:0002036)
2.4 12.0 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
2.3 38.3 GO:0006662 glycerol ether metabolic process(GO:0006662)
2.2 13.3 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
2.2 10.9 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
2.0 6.1 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
2.0 26.1 GO:0001778 plasma membrane repair(GO:0001778)
2.0 11.8 GO:0060723 regulation of spongiotrophoblast cell proliferation(GO:0060721) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
1.9 7.8 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
1.8 5.4 GO:0019086 late viral transcription(GO:0019086)
1.8 5.3 GO:0042335 cuticle development(GO:0042335)
1.7 10.2 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
1.7 6.8 GO:1903576 response to L-arginine(GO:1903576)
1.7 8.4 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
1.7 23.5 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
1.6 3.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
1.5 6.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
1.4 4.3 GO:0033058 directional locomotion(GO:0033058)
1.4 11.0 GO:0098734 macromolecule depalmitoylation(GO:0098734)
1.4 14.9 GO:0070327 thyroid hormone transport(GO:0070327)
1.3 6.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
1.3 4.0 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
1.3 10.4 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
1.3 2.6 GO:1903179 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
1.3 7.6 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
1.2 19.9 GO:0042448 progesterone metabolic process(GO:0042448)
1.2 3.7 GO:0046724 oxalic acid secretion(GO:0046724)
1.2 16.7 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
1.2 4.6 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
1.2 9.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
1.0 12.7 GO:1900122 positive regulation of receptor binding(GO:1900122)
1.0 13.4 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.9 24.4 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.9 13.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.9 7.1 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.9 8.0 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.9 8.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.8 2.3 GO:0048749 compound eye development(GO:0048749)
0.8 2.3 GO:0046864 isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.7 2.1 GO:0016598 protein arginylation(GO:0016598)
0.7 3.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.7 2.7 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.7 8.0 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.6 9.9 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.6 7.8 GO:0007512 adult heart development(GO:0007512)
0.6 7.2 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.6 11.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.6 17.0 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.6 2.3 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.6 4.4 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.5 1.6 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.5 9.2 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.5 4.8 GO:0035878 nail development(GO:0035878)
0.5 3.7 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.5 18.0 GO:0008206 bile acid metabolic process(GO:0008206)
0.5 7.0 GO:0007614 short-term memory(GO:0007614)
0.5 3.0 GO:0060665 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.5 5.1 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.5 25.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.5 2.7 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.4 2.8 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.4 9.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.4 24.1 GO:0034605 cellular response to heat(GO:0034605)
0.4 11.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.3 14.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.3 2.5 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.3 15.0 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.3 6.1 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.3 12.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.3 7.1 GO:0006783 heme biosynthetic process(GO:0006783)
0.2 7.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.2 0.9 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.2 1.2 GO:2000504 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.2 17.7 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.2 4.8 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.2 17.9 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.2 3.1 GO:0006301 postreplication repair(GO:0006301)
0.2 15.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.2 7.9 GO:0014009 glial cell proliferation(GO:0014009)
0.2 1.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.2 4.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.2 1.0 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.2 1.0 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.2 1.1 GO:0071000 response to magnetism(GO:0071000)
0.2 1.7 GO:0007097 nuclear migration(GO:0007097)
0.1 1.1 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1 7.3 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.1 0.6 GO:2001171 positive regulation of ATP biosynthetic process(GO:2001171)
0.1 0.5 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.8 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 8.1 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.1 0.3 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.1 0.4 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1 0.6 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 14.8 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 1.1 GO:0005513 detection of calcium ion(GO:0005513)
0.1 5.1 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 3.8 GO:0032094 response to food(GO:0032094)
0.1 4.0 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 0.9 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.1 0.2 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.5 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 81.2 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.1 2.1 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 1.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 13.6 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 10.1 GO:0007015 actin filament organization(GO:0007015)
0.0 0.6 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 1.3 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.0 0.5 GO:0044804 nucleophagy(GO:0044804)
0.0 0.1 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 2.6 GO:0030073 insulin secretion(GO:0030073)
0.0 0.2 GO:0001302 replicative cell aging(GO:0001302)
0.0 3.6 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 3.8 GO:0006006 glucose metabolic process(GO:0006006)
0.0 2.8 GO:0021510 spinal cord development(GO:0021510)
0.0 1.9 GO:0006342 chromatin silencing(GO:0006342)
0.0 2.1 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 0.4 GO:0001709 cell fate determination(GO:0001709)
0.0 0.8 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.2 GO:0080182 histone H3-K4 trimethylation(GO:0080182)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
7.4 44.5 GO:0032280 symmetric synapse(GO:0032280)
4.4 35.1 GO:0097452 GAIT complex(GO:0097452)
3.6 21.8 GO:0033269 internode region of axon(GO:0033269)
3.3 13.3 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
3.3 16.7 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
2.7 26.9 GO:0005641 nuclear envelope lumen(GO:0005641)
1.9 24.4 GO:0032593 insulin-responsive compartment(GO:0032593)
1.8 23.5 GO:0031143 pseudopodium(GO:0031143)
1.5 19.1 GO:0008385 IkappaB kinase complex(GO:0008385)
1.3 6.7 GO:0016035 zeta DNA polymerase complex(GO:0016035)
1.3 3.8 GO:0032173 septin collar(GO:0032173)
1.2 6.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
1.1 10.9 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
1.1 7.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
1.0 29.0 GO:0042629 mast cell granule(GO:0042629)
0.9 15.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.7 4.6 GO:0005827 polar microtubule(GO:0005827)
0.6 17.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.6 5.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.6 97.6 GO:0030018 Z disc(GO:0030018)
0.5 17.1 GO:0005605 basal lamina(GO:0005605)
0.5 19.8 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.5 26.1 GO:0030315 T-tubule(GO:0030315)
0.4 7.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.4 3.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.4 8.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.4 9.0 GO:0035371 microtubule plus-end(GO:0035371)
0.3 9.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.3 1.9 GO:0089701 U2AF(GO:0089701)
0.3 15.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.3 9.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.3 4.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.3 4.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.3 17.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 6.8 GO:0042588 zymogen granule(GO:0042588)
0.2 3.4 GO:0005839 proteasome core complex(GO:0005839)
0.2 3.6 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.2 4.0 GO:0005922 connexon complex(GO:0005922)
0.2 2.3 GO:0097542 ciliary tip(GO:0097542)
0.2 3.7 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.0 GO:0031415 NatA complex(GO:0031415)
0.1 10.4 GO:0031902 late endosome membrane(GO:0031902)
0.1 4.1 GO:0000421 autophagosome membrane(GO:0000421)
0.1 30.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 4.8 GO:0001772 immunological synapse(GO:0001772)
0.1 7.2 GO:0031594 neuromuscular junction(GO:0031594)
0.1 3.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 12.0 GO:0042383 sarcolemma(GO:0042383)
0.1 81.5 GO:0031966 mitochondrial membrane(GO:0031966)
0.1 0.9 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 1.6 GO:0032433 filopodium tip(GO:0032433)
0.1 1.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 3.7 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 4.0 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 1.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.6 GO:0071541 eukaryotic 43S preinitiation complex(GO:0016282) eukaryotic 48S preinitiation complex(GO:0033290) eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 77.8 GO:0005739 mitochondrion(GO:0005739)
0.1 32.1 GO:0000139 Golgi membrane(GO:0000139)
0.1 4.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 5.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.8 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 7.4 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
23.8 71.3 GO:0004769 steroid delta-isomerase activity(GO:0004769)
8.8 35.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
7.4 44.5 GO:0001515 opioid peptide activity(GO:0001515)
4.9 19.8 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
4.8 19.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
4.6 13.8 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
4.5 17.9 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
4.4 13.2 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
3.3 13.3 GO:0019002 GMP binding(GO:0019002)
3.3 9.8 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
2.8 8.5 GO:0003990 acetylcholinesterase activity(GO:0003990)
2.8 8.3 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
2.7 24.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
2.6 15.4 GO:0035473 lipase binding(GO:0035473)
2.5 19.8 GO:0043237 laminin-1 binding(GO:0043237)
2.4 12.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
2.2 24.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
2.1 8.4 GO:0031686 A1 adenosine receptor binding(GO:0031686)
2.0 18.0 GO:0032052 bile acid binding(GO:0032052)
2.0 11.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.6 4.8 GO:0071532 ankyrin repeat binding(GO:0071532)
1.6 11.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
1.5 4.6 GO:0031208 POZ domain binding(GO:0031208)
1.5 6.1 GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294)
1.5 10.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
1.4 29.0 GO:0051428 peptide hormone receptor binding(GO:0051428)
1.4 9.5 GO:0031852 mu-type opioid receptor binding(GO:0031852)
1.3 10.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.2 14.9 GO:0070324 thyroid hormone binding(GO:0070324)
1.2 6.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
1.2 3.7 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
1.2 17.0 GO:0033691 sialic acid binding(GO:0033691)
1.1 8.8 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
1.0 8.1 GO:0016421 CoA carboxylase activity(GO:0016421)
1.0 8.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
1.0 12.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.9 7.4 GO:0004630 phospholipase D activity(GO:0004630)
0.9 12.7 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.8 15.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.7 3.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.7 8.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.7 45.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.7 13.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.6 3.0 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.6 26.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.5 9.1 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.5 1.5 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.5 10.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.5 4.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.4 7.2 GO:0044548 S100 protein binding(GO:0044548)
0.4 17.0 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.4 2.7 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.4 4.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.4 3.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.4 6.1 GO:0005523 tropomyosin binding(GO:0005523)
0.4 15.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.3 9.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3 11.9 GO:0008009 chemokine activity(GO:0008009) CCR chemokine receptor binding(GO:0048020)
0.3 2.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.2 2.3 GO:0019841 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.2 36.8 GO:0044325 ion channel binding(GO:0044325)
0.2 4.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 5.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 2.6 GO:0050897 cobalt ion binding(GO:0050897)
0.2 8.0 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.2 1.0 GO:0019862 IgA binding(GO:0019862)
0.2 1.9 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.2 2.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 1.3 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.2 1.1 GO:0003680 AT DNA binding(GO:0003680)
0.2 0.9 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 1.1 GO:0071253 connexin binding(GO:0071253)
0.2 4.0 GO:0008301 DNA binding, bending(GO:0008301)
0.2 2.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 4.5 GO:0030371 translation repressor activity(GO:0030371)
0.2 8.2 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.2 9.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 3.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.2 12.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 12.9 GO:0004620 phospholipase activity(GO:0004620)
0.1 14.4 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 2.1 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.1 9.9 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 2.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 6.8 GO:0051018 protein kinase A binding(GO:0051018)
0.1 2.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 12.5 GO:0030674 protein binding, bridging(GO:0030674)
0.1 0.8 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 4.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.4 GO:0036004 GAF domain binding(GO:0036004)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 7.8 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 5.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 2.1 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.1 8.9 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.1 1.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.5 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.1 9.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 1.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 65.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 2.1 GO:0030145 manganese ion binding(GO:0030145)
0.0 5.1 GO:0001948 glycoprotein binding(GO:0001948)
0.0 22.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 4.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 2.8 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 4.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.1 GO:0015459 calcium-activated potassium channel activity(GO:0015269) potassium channel regulator activity(GO:0015459)
0.0 6.3 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 14.8 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 1.8 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 1.9 GO:0019843 rRNA binding(GO:0019843)
0.0 3.3 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.6 GO:0003743 translation initiation factor activity(GO:0003743)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 71.1 PID AP1 PATHWAY AP-1 transcription factor network
0.8 24.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.7 7.3 PID RAS PATHWAY Regulation of Ras family activation
0.6 19.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.5 21.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.4 8.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.3 7.6 PID S1P S1P2 PATHWAY S1P2 pathway
0.3 10.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.3 7.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.3 11.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.3 21.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 11.8 PID TNF PATHWAY TNF receptor signaling pathway
0.1 6.1 PID BMP PATHWAY BMP receptor signaling
0.1 2.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 2.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 15.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.6 PID ARF 3PATHWAY Arf1 pathway
0.1 19.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 2.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 2.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 69.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
1.5 21.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.5 18.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
1.4 24.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
1.3 36.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
1.0 21.9 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
1.0 49.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.7 8.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.7 9.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.6 8.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.5 10.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.5 4.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.5 8.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.5 9.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.4 13.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.4 8.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.3 12.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.3 15.8 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.3 10.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 21.0 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.3 7.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.3 4.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.2 13.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.2 4.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 36.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 4.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 3.0 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.2 2.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 2.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 2.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.2 8.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 19.8 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 3.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 5.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 3.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 4.4 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 2.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 4.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis