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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Nkx3-1

Z-value: 0.64

Motif logo

Transcription factors associated with Nkx3-1

Gene Symbol Gene ID Gene Info
ENSRNOG00000015477 NK3 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx3-1rn6_v1_chr15_+_51065316_510653160.106.5e-02Click!

Activity profile of Nkx3-1 motif

Sorted Z-values of Nkx3-1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_120446455 21.10 ENSRNOT00000085161
ENSRNOT00000042854
ENSRNOT00000037199
cAMP regulated phosphoprotein 21
chr11_+_54619129 13.20 ENSRNOT00000059924
T cell receptor associated transmembrane adaptor 1
chr15_+_31642169 13.15 ENSRNOT00000072362

chr4_+_70572942 13.11 ENSRNOT00000051964

chr15_+_31417147 12.31 ENSRNOT00000092182

chr15_-_29761117 12.17 ENSRNOT00000075194

chr19_-_10681145 11.68 ENSRNOT00000022167
C-C motif chemokine ligand 22
chr15_+_31097291 11.65 ENSRNOT00000075456

chr1_-_104202591 11.31 ENSRNOT00000035512
E2F transcription factor 8
chr15_+_30570483 11.22 ENSRNOT00000071740

chr10_-_31419235 9.89 ENSRNOT00000059496
cytoplasmic FMR1 interacting protein 2
chr15_+_31010891 9.50 ENSRNOT00000088134

chr2_-_203413124 9.48 ENSRNOT00000077898
ENSRNOT00000056140
CD101 molecule
chr2_-_132551235 9.41 ENSRNOT00000058250
rCG65904-like
chr9_+_60900213 8.95 ENSRNOT00000017859
coiled-coil domain containing 150
chr2_+_127625683 8.77 ENSRNOT00000015474
heat shock protein 4-like
chr15_-_30019055 8.65 ENSRNOT00000073984

chr4_-_128266082 8.29 ENSRNOT00000039549
nucleoporin 50
chrX_+_70461718 8.26 ENSRNOT00000078233
ENSRNOT00000003789
kinesin family member 4A
chr15_-_29246222 7.85 ENSRNOT00000081806

chr8_-_13906355 7.70 ENSRNOT00000029634
centrosomal protein 295
chr13_-_95348913 7.70 ENSRNOT00000057879
AKT serine/threonine kinase 3
chr15_-_30323833 7.66 ENSRNOT00000071631

chr1_+_253221812 7.13 ENSRNOT00000085880
ENSRNOT00000054753
kinesin family member 20B
chr15_-_45524582 6.98 ENSRNOT00000081912
guanylate cyclase 1 soluble subunit beta 2
chr4_-_69163881 6.86 ENSRNOT00000048779
trypsin X5
chr4_+_52199416 6.85 ENSRNOT00000009537
sperm adhesion molecule 1
chr1_-_205630073 6.62 ENSRNOT00000037064
testis expressed 36
chr3_+_80468154 6.22 ENSRNOT00000021837
cytoskeleton associated protein 5
chr3_+_148790979 6.16 ENSRNOT00000085757
kinesin family member 3B
chr1_-_205669760 6.09 ENSRNOT00000086703
testis expressed 36
chr15_-_88670349 5.90 ENSRNOT00000012881
ring finger protein 219
chr2_-_165591110 5.85 ENSRNOT00000091140
intraflagellar transport 80
chr3_+_15379109 5.83 ENSRNOT00000036495
MORN repeat containing 5
chr6_-_25507073 5.81 ENSRNOT00000061176
phospholipase B1
chr14_-_3446611 5.73 ENSRNOT00000080901
bromodomain testis associated
chr1_+_81579736 5.67 ENSRNOT00000071339
CD177 antigen-like
chr12_+_37878653 5.65 ENSRNOT00000091084
phosphatidylinositol transfer protein, membrane-associated 2
chr3_+_150055749 5.53 ENSRNOT00000055335
actin-like 10
chr1_+_156552328 5.50 ENSRNOT00000055401
discs large MAGUK scaffold protein 2
chr5_+_16845631 5.40 ENSRNOT00000047889
coiled-coil-helix-coiled-coil-helix domain containing 7
chr4_-_176596591 5.36 ENSRNOT00000086365
RecQ like helicase
chr15_+_32012543 5.34 ENSRNOT00000078174

chr14_+_81858737 5.33 ENSRNOT00000029784
ENSRNOT00000058068
ENSRNOT00000058067
DNA polymerase nu
chrX_-_40086870 5.27 ENSRNOT00000010027
small muscle protein, X-linked
chr7_+_40217991 5.26 ENSRNOT00000085684
centrosomal protein 290
chr19_-_37819789 5.22 ENSRNOT00000036702
centromere protein T
chrX_+_29504349 5.08 ENSRNOT00000005981
transcription elongation factor A N-terminal and central domain containing
chr1_+_106405002 5.08 ENSRNOT00000074027
probable isocitrate dehydrogenase [NAD] gamma 2, mitochondrial
chr19_+_56220755 5.06 ENSRNOT00000023452
tubulin, beta 3 class III
chr1_+_82816984 5.05 ENSRNOT00000074588
CD177 antigen-like
chr4_-_6046477 5.00 ENSRNOT00000073925
chaperonin containing TCP1, subunit 8 (theta)-like 1
chr18_-_74478341 4.99 ENSRNOT00000074572
solute carrier family 14 member 1
chr15_-_33285779 4.99 ENSRNOT00000036150
cadherin 24
chr19_+_38162515 4.98 ENSRNOT00000027117
solute carrier family 7 member 6
chr10_-_17721233 4.95 ENSRNOT00000031337
small integral membrane protein 23
chr1_+_82934134 4.94 ENSRNOT00000072914
CD177 antigen-like
chr15_+_47455690 4.90 ENSRNOT00000075276
serine protease 55-like
chr11_+_42936028 4.86 ENSRNOT00000074653

chr4_+_22898527 4.79 ENSRNOT00000072455
ENSRNOT00000076123
DBF4 zinc finger
chr1_+_252497452 4.74 ENSRNOT00000075598
STAM binding protein-like 1
chr1_-_189199376 4.72 ENSRNOT00000021027
uromodulin
chr10_+_109950988 4.68 ENSRNOT00000071293
similar to Lung carbonyl reductase [NADPH] (NADPH-dependent carbonyl reductase) (LCR) (Adipocyte P27 protein) (AP27)
chr15_-_55209342 4.57 ENSRNOT00000021752
RB transcriptional corepressor 1
chr4_+_160020472 4.52 ENSRNOT00000078802
poly (ADP-ribose) polymerase family, member 11
chr7_+_27620458 4.47 ENSRNOT00000059532
similar to FLJ25323 protein
chr10_+_72147816 4.47 ENSRNOT00000090085
SUMO-conjugating enzyme UBC9-like
chr14_+_3204390 4.46 ENSRNOT00000088078
glomulin, FKBP associated protein
chr2_+_202200797 4.41 ENSRNOT00000042263
ENSRNOT00000071938
sperm associated antigen 17
chr4_-_6062641 4.38 ENSRNOT00000074846
chaperonin containing TCP1, subunit 8 (theta)-like 1
chr16_+_34795971 4.27 ENSRNOT00000043510
myeloid-associated differentiation marker-like
chr8_-_78397123 4.21 ENSRNOT00000087270
ENSRNOT00000084925
transcription factor 12
chr11_+_53081025 4.21 ENSRNOT00000002700
BBX, HMG-box containing
chr3_-_112371664 4.19 ENSRNOT00000079606
ENSRNOT00000012636
leucine-rich repeat-containing protein 57-like
chr6_-_27460038 4.14 ENSRNOT00000036815
dynein regulatory complex subunit 1
chr9_-_27761365 4.14 ENSRNOT00000018552
potassium voltage-gated channel subfamily Q member 5
chr1_+_101410019 4.09 ENSRNOT00000042039
luteinizing hormone beta polypeptide
chr1_-_277867630 3.93 ENSRNOT00000054679
ENSRNOT00000091038
ENSRNOT00000079869
actin-binding LIM protein 1
chr7_-_58149061 3.84 ENSRNOT00000005157
tryptophan hydroxylase 2
chr2_+_143895982 3.81 ENSRNOT00000080026
SPT20 homolog, SAGA complex component
chr2_-_54963448 3.78 ENSRNOT00000017886
prostaglandin E receptor 4
chr16_+_56247659 3.73 ENSRNOT00000017452
tumor suppressor candidate 3
chr8_+_5606592 3.71 ENSRNOT00000011727
matrix metallopeptidase 12
chr1_-_277939039 3.71 ENSRNOT00000079579
ENSRNOT00000086726
actin-binding LIM protein 1
chr13_-_109770199 3.69 ENSRNOT00000043672
family with sequence similarity 71, member A
chr14_+_100135271 3.67 ENSRNOT00000032965
F-box protein 48
chr10_+_90985653 3.63 ENSRNOT00000093364
coiled-coil domain containing 103
chr2_+_123791335 3.63 ENSRNOT00000077096
adenosine deaminase domain containing 1
chr20_-_27578244 3.62 ENSRNOT00000000708
family with sequence similarity 26, member D
chr15_+_31895223 3.60 ENSRNOT00000092202

chr7_+_127964752 3.60 ENSRNOT00000038168
hypothetical gene supported by NM_053561; AF062594
chr3_+_54734015 3.56 ENSRNOT00000034341
similar to protein expressed in prostate, ovary, testis, and placenta 8 isoform 2
chr10_+_11879418 3.54 ENSRNOT00000068577
RGD1561796
chr9_-_27761733 3.51 ENSRNOT00000040034
potassium voltage-gated channel subfamily Q member 5
chr4_+_159403501 3.48 ENSRNOT00000086525
A-kinase anchoring protein 3
chr9_-_15700235 3.42 ENSRNOT00000088713
ENSRNOT00000035907
transcriptional regulating factor 1
chr3_-_161294125 3.41 ENSRNOT00000021143
spermatogenesis associated 25
chr13_+_90723092 3.41 ENSRNOT00000010146
ATP-sensitive inward rectifier potassium channel 10
chr13_-_82295123 3.39 ENSRNOT00000090120
similar to hypothetical protein FLJ10706
chr20_-_399933 3.37 ENSRNOT00000000953
olfactory receptor 1671
chrX_-_158261717 3.36 ENSRNOT00000086804
similar to RIKEN cDNA 1700001F22
chr10_-_7029136 3.35 ENSRNOT00000091942

chr17_-_57526461 3.35 ENSRNOT00000072723
ankyrin repeat domain-containing protein 26-like
chr9_-_81772851 3.34 ENSRNOT00000032719
ubiquitin specific peptidase 37
chr1_+_101249522 3.25 ENSRNOT00000033882
solute carrier family 6, member 16
chr2_-_137331140 3.17 ENSRNOT00000048546
similar to T-cell activation Rho GTPase-activating protein isoform b
chr8_-_50603591 3.13 ENSRNOT00000077748
similar to RIKEN cDNA 4931429L15
chr14_+_7630482 3.10 ENSRNOT00000091581
similar to hypothetical protein MGC26744
chr1_-_82901917 3.05 ENSRNOT00000035648
CD177 antigen-like
chr2_+_43271092 3.04 ENSRNOT00000017571
mesoderm induction early response 1, family member 3
chr10_-_70181708 3.00 ENSRNOT00000076598
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr3_+_146695344 2.99 ENSRNOT00000010955
GINS complex subunit 1
chr3_-_112385528 2.99 ENSRNOT00000049756
leucine rich repeat containing 57
chr18_+_70996044 2.96 ENSRNOT00000024950
ENSRNOT00000066336
dymeclin
chr5_+_147714163 2.95 ENSRNOT00000012663
MARCKS-like 1
chr17_+_85500113 2.90 ENSRNOT00000091937

chr6_+_27887797 2.89 ENSRNOT00000015827
additional sex combs like 2, transcriptional regulator
chr2_-_39007976 2.86 ENSRNOT00000064292
zinc finger, SWIM-type containing 6
chr19_-_14945302 2.78 ENSRNOT00000079391

chr5_+_135413275 2.71 ENSRNOT00000012263
GC-rich promoter binding protein 1-like 1
chrX_-_124162058 2.67 ENSRNOT00000071436
similar to B-cell translocation gene 1
chr10_+_65161152 2.65 ENSRNOT00000011608
crystallin, beta A1
chrX_-_38468360 2.54 ENSRNOT00000045285
MAP7 domain containing 2
chr6_-_55698757 2.54 ENSRNOT00000085146
leucine rich repeat containing 72
chr1_-_20962526 2.54 ENSRNOT00000061332
ENSRNOT00000017322
ENSRNOT00000017412
ENSRNOT00000079688
ENSRNOT00000017417
erythrocyte membrane protein band 4.1-like 2
chr9_+_24066303 2.53 ENSRNOT00000018163
cysteine-rich secretory protein 3
chr5_-_133067245 2.51 ENSRNOT00000033163
selection and upkeep of intraepithelial T cells 10
chr1_-_7480825 2.50 ENSRNOT00000048754
phosphatase and actin regulator 2
chr11_-_66759402 2.49 ENSRNOT00000003326
hematopoietic cell specific Lyn substrate 1
chr8_+_117600749 2.49 ENSRNOT00000047482
NCK interacting protein with SH3 domain
chrX_-_82699487 2.49 ENSRNOT00000081625
ribosomal protein S6 kinase A6
chr13_-_105684374 2.47 ENSRNOT00000073142
spermatogenesis associated 17
chr1_-_81559685 2.43 ENSRNOT00000075282
CD177 antigen-like
chr12_+_12859661 2.42 ENSRNOT00000001404
ubiquitin specific peptidase 42
chr13_-_15395617 2.40 ENSRNOT00000046060
similar to contactin associated protein-like 5 isoform 1
chr6_+_102477036 2.38 ENSRNOT00000087132
RAD51 paralog B
chr1_-_99632845 2.37 ENSRNOT00000049123
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 pseudogene
chr14_+_48726045 2.34 ENSRNOT00000086646
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr20_-_1818800 2.33 ENSRNOT00000000990
RT1 class Ib, locus M3, gene 1
chr12_+_19303387 2.32 ENSRNOT00000001820
COP9 signalosome subunit 6
chr13_+_89524329 2.32 ENSRNOT00000004279
myelin protein zero
chr4_-_117531480 2.29 ENSRNOT00000021120
N-acetyltransferase 8 (GCN5-related) family member 5
chr2_+_86914989 2.29 ENSRNOT00000085164
ENSRNOT00000081966
zinc finger protein 457-like
chr9_+_71230108 2.27 ENSRNOT00000018326
cAMP responsive element binding protein 1
chr15_-_70399924 2.22 ENSRNOT00000087940
diaphanous-related formin 3
chr6_+_26390689 2.21 ENSRNOT00000079762
ENSRNOT00000091528
intraflagellar transport 172
chr7_-_116504853 2.20 ENSRNOT00000056557
similar to Ly6-C antigen gene
chr18_-_36513317 2.18 ENSRNOT00000025453
PLAC8-like 1
chr17_-_10439691 2.15 ENSRNOT00000024151
cadherin-related family member 2
chr2_-_198942732 2.10 ENSRNOT00000000109
ENSRNOT00000073913
CD160 molecule
chr15_+_2526368 2.08 ENSRNOT00000048713
ENSRNOT00000074803
dual specificity phosphatase 13
dual specificity phosphatase 13
chr3_-_21609853 2.04 ENSRNOT00000012160
phosducin-like
chr1_+_255564409 2.04 ENSRNOT00000081786
B-TFIID TATA-box binding protein associated factor 1
chr2_-_49170025 2.04 ENSRNOT00000060595
poly (ADP-ribose) polymerase family, member 8
chr1_+_30863217 1.97 ENSRNOT00000015421
ring finger protein 146
chr1_+_81372650 1.91 ENSRNOT00000088829
zinc finger protein 428
chr7_+_74350479 1.90 ENSRNOT00000089034

chr3_+_101899068 1.90 ENSRNOT00000079600
ENSRNOT00000006256
mucin 15, cell surface associated
chr19_-_56799445 1.89 ENSRNOT00000024491
similar to TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr8_-_39201588 1.88 ENSRNOT00000011226
STT3A, catalytic subunit of the oligosaccharyltransferase complex
chr7_-_139542461 1.86 ENSRNOT00000089425
SUMO1/sentrin specific peptidase 1
chr3_-_114728410 1.82 ENSRNOT00000000181
glycine amidinotransferase
chr4_-_129430251 1.81 ENSRNOT00000067881
family with sequence similarity 19 member A4, C-C motif chemokine like
chr12_+_4546287 1.81 ENSRNOT00000001416
HIG1 hypoxia inducible domain family, member 2A-like 1
chr15_+_31051414 1.80 ENSRNOT00000090250

chr1_+_13595295 1.80 ENSRNOT00000079250
NHS-like 1
chr20_+_34895059 1.79 ENSRNOT00000084420
anti-silencing function 1A histone chaperone
chr12_-_47438931 1.78 ENSRNOT00000050782
similar to RIKEN cDNA 2210016L21 gene
chr7_-_68549763 1.78 ENSRNOT00000078014
solute carrier family 16 member 7
chr9_-_65957101 1.77 ENSRNOT00000014094
membrane palmitoylated protein 4
chr18_+_87415531 1.76 ENSRNOT00000072475

chr5_+_137546860 1.76 ENSRNOT00000074431
olfactory receptor 858
chr11_+_87224421 1.75 ENSRNOT00000000308
DiGeorge syndrome critical region gene 14
chr14_-_6284145 1.74 ENSRNOT00000044065
zinc finger protein 951
chr14_-_6358720 1.74 ENSRNOT00000048419
zinc finger protein 951
chr7_+_2645196 1.74 ENSRNOT00000083899
timeless circadian clock
chr1_-_165891627 1.73 ENSRNOT00000038408
RELT tumor necrosis factor receptor
chr13_+_71110064 1.64 ENSRNOT00000088329
regulator of G-protein signaling 8
chr5_+_8876044 1.60 ENSRNOT00000008877
COP9 signalosome subunit 5
chr10_+_34414854 1.59 ENSRNOT00000074980
similar to olfactory receptor 1394
chrX_-_21945305 1.58 ENSRNOT00000065084
spermatogenesis associated multipass transmembrane protein 2
chr8_-_48727154 1.56 ENSRNOT00000088471
trafficking protein particle complex 4
chr9_-_82336806 1.50 ENSRNOT00000024667
solute carrier family 23, member 3
chr18_+_15738809 1.50 ENSRNOT00000075444
microtubule-associated protein, RP/EB family, member 2
chr8_-_48726963 1.44 ENSRNOT00000016145
trafficking protein particle complex 4
chr9_+_100885051 1.43 ENSRNOT00000082987

chr1_-_67065797 1.42 ENSRNOT00000048152
vomeronasal 1 receptor 46
chr18_+_3163214 1.39 ENSRNOT00000017291
RB binding protein 8, endonuclease
chr1_-_66639205 1.36 ENSRNOT00000082190
eukaryotic translation initiation factor 3 subunit E-like
chr4_-_118487633 1.36 ENSRNOT00000068093
germ cell-less, spermatogenesis associated 1
chr12_-_30304036 1.35 ENSRNOT00000001218
nuclear protein 2, transcriptional regulator
chr3_-_111266542 1.33 ENSRNOT00000031672
INO80 complex subunit
chr2_-_231877307 1.31 ENSRNOT00000073860
La ribonucleoprotein domain family, member 7
chr6_+_125876109 1.26 ENSRNOT00000091300
cleavage and polyadenylation specific factor 2
chr2_-_144808245 1.24 ENSRNOT00000087849
uncharacterized LOC102552324
chr17_-_42226377 1.22 ENSRNOT00000024536
similar to mKIAA0319 protein
chr6_+_83083740 1.18 ENSRNOT00000007600
leucine rich repeat and fibronectin type III domain containing 5
chr8_+_17928358 1.16 ENSRNOT00000029911
methyl-CpG binding domain protein 3-like 2
chr5_+_139783951 1.15 ENSRNOT00000081333
regulating synaptic membrane exocytosis 3
chr2_+_189714754 1.15 ENSRNOT00000086285
GATA zinc finger domain containing 2B

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx3-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.1 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
1.9 5.7 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
1.9 11.3 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
1.6 13.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
1.5 4.6 GO:1903943 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
1.3 3.8 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
1.2 9.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.2 4.7 GO:0072218 ascending thin limb development(GO:0072021) metanephric ascending thin limb development(GO:0072218)
1.2 8.3 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
1.1 3.4 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
1.1 4.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
1.0 6.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.9 3.7 GO:1902741 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.8 5.0 GO:0071918 urea transmembrane transport(GO:0071918)
0.8 2.3 GO:0002477 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
0.8 2.3 GO:0032916 positive regulation of transforming growth factor beta3 production(GO:0032916)
0.6 5.8 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.6 3.8 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.6 3.8 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.6 2.5 GO:0042531 regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.6 5.8 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.6 1.7 GO:1904976 cellular response to bleomycin(GO:1904976)
0.5 6.8 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.5 2.0 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.5 3.0 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.5 5.5 GO:0046710 GDP metabolic process(GO:0046710)
0.5 2.9 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.5 1.8 GO:1990402 embryonic liver development(GO:1990402)
0.4 5.4 GO:0000733 DNA strand renaturation(GO:0000733)
0.4 5.2 GO:0051382 kinetochore assembly(GO:0051382)
0.4 2.1 GO:1904970 brush border assembly(GO:1904970)
0.4 5.3 GO:0019985 translesion synthesis(GO:0019985)
0.4 2.7 GO:2000210 positive regulation of anoikis(GO:2000210)
0.4 3.6 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.4 3.9 GO:0000338 protein deneddylation(GO:0000338)
0.4 1.1 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.3 4.5 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.3 5.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.3 0.9 GO:0046671 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) negative regulation of retinal cell programmed cell death(GO:0046671) cellular response to fluoride(GO:1902618)
0.3 21.1 GO:0034605 cellular response to heat(GO:0034605)
0.3 2.5 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.3 7.7 GO:0045793 positive regulation of cell size(GO:0045793)
0.3 3.4 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.3 3.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.3 3.0 GO:1902969 mitotic DNA replication(GO:1902969)
0.3 2.0 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.3 1.1 GO:0071651 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877) positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.3 1.9 GO:0043686 co-translational protein modification(GO:0043686)
0.3 2.7 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.3 3.7 GO:0015693 magnesium ion transport(GO:0015693) magnesium ion transmembrane transport(GO:1903830)
0.3 1.9 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.3 9.5 GO:0006458 'de novo' protein folding(GO:0006458)
0.2 11.7 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.2 0.5 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.2 1.4 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.2 1.3 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 1.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2 1.0 GO:0019563 glycerol catabolic process(GO:0019563)
0.2 4.1 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.2 0.6 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
0.2 2.6 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.2 2.2 GO:0061525 hindgut development(GO:0061525)
0.2 0.5 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.2 0.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 5.1 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.2 0.5 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2 1.6 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.2 9.5 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.1 11.1 GO:0046068 cGMP metabolic process(GO:0046068)
0.1 6.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 4.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.7 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 5.5 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 0.8 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 5.0 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.1 0.6 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725)
0.1 2.1 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.1 8.8 GO:0006986 response to unfolded protein(GO:0006986)
0.1 0.4 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 1.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 8.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 4.5 GO:0016925 protein sumoylation(GO:0016925)
0.1 1.0 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 7.6 GO:0051028 mRNA transport(GO:0051028)
0.1 2.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 1.0 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.1 1.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 1.4 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.1 4.9 GO:1902117 positive regulation of organelle assembly(GO:1902117)
0.1 3.2 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 2.3 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.1 1.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.3 GO:1904430 mitotic telomere maintenance via semi-conservative replication(GO:1902990) negative regulation of t-circle formation(GO:1904430)
0.1 0.3 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.7 GO:0097240 telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.2 GO:0060988 lipid tube assembly(GO:0060988)
0.1 0.8 GO:2000650 negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 2.0 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.9 GO:0031297 replication fork processing(GO:0031297)
0.1 0.5 GO:0002118 aggressive behavior(GO:0002118)
0.0 2.3 GO:0051931 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.5 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 2.1 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 2.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.2 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.5 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.4 GO:0008343 adult feeding behavior(GO:0008343)
0.0 5.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.6 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 2.0 GO:0090263 protein autoubiquitination(GO:0051865) positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.6 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.0 1.7 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.5 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.1 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 1.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 4.0 GO:0006941 striated muscle contraction(GO:0006941)
0.0 6.1 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.6 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.0 2.4 GO:0016358 dendrite development(GO:0016358)
0.0 0.2 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.1 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 2.4 GO:0016579 protein deubiquitination(GO:0016579)
0.0 1.2 GO:0035418 protein localization to synapse(GO:0035418)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.4 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.6 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.3 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.2 GO:0009642 response to light intensity(GO:0009642)
0.0 0.5 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 1.8 GO:0007601 visual perception(GO:0007601) sensory perception of light stimulus(GO:0050953)
0.0 1.4 GO:0007030 Golgi organization(GO:0007030)
0.0 0.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 1.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 4.7 GO:0045666 positive regulation of neuron differentiation(GO:0045666)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.2 GO:0016939 kinesin II complex(GO:0016939)
1.1 2.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
1.1 5.3 GO:0005927 muscle tendon junction(GO:0005927)
1.0 3.0 GO:0000811 GINS complex(GO:0000811)
0.9 4.4 GO:1990716 axonemal central apparatus(GO:1990716)
0.8 2.3 GO:0032398 MHC class Ib protein complex(GO:0032398)
0.8 4.6 GO:0035189 Rb-E2F complex(GO:0035189)
0.8 2.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.8 3.0 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.7 13.2 GO:0042101 T cell receptor complex(GO:0042101)
0.7 9.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.6 11.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.5 2.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.5 7.1 GO:1990023 mitotic spindle pole(GO:0097431) mitotic spindle midzone(GO:1990023)
0.4 4.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.4 2.2 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.3 5.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.3 5.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.3 3.8 GO:0000124 SAGA complex(GO:0000124)
0.3 7.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3 2.2 GO:0030891 VCB complex(GO:0030891)
0.2 3.0 GO:0030008 TRAPP complex(GO:0030008)
0.2 5.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.2 8.9 GO:0008180 COP9 signalosome(GO:0008180)
0.2 3.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 1.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 5.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 3.4 GO:0097449 astrocyte projection(GO:0097449)
0.2 1.4 GO:0033290 eukaryotic 43S preinitiation complex(GO:0016282) eukaryotic 48S preinitiation complex(GO:0033290)
0.2 1.0 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.2 8.3 GO:0045171 intercellular bridge(GO:0045171)
0.1 2.5 GO:0042581 specific granule(GO:0042581)
0.1 13.1 GO:0031225 anchored component of membrane(GO:0031225)
0.1 8.3 GO:0005643 nuclear pore(GO:0005643)
0.1 2.0 GO:0000242 pericentriolar material(GO:0000242)
0.1 0.7 GO:0030870 Mre11 complex(GO:0030870)
0.1 5.9 GO:0030118 clathrin coat(GO:0030118)
0.1 0.9 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.7 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 0.8 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 7.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.3 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 6.6 GO:0031526 brush border membrane(GO:0031526)
0.1 7.7 GO:0005814 centriole(GO:0005814)
0.1 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.1 4.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.5 GO:1990752 microtubule end(GO:1990752)
0.0 4.1 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 1.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 4.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 7.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 6.4 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 2.5 GO:0001650 fibrillar center(GO:0001650)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.6 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.5 GO:0031201 SNARE complex(GO:0031201)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
1.5 4.5 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
1.3 5.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
1.2 5.0 GO:0015265 urea channel activity(GO:0015265)
1.0 15.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.9 4.6 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.9 5.4 GO:0009378 four-way junction helicase activity(GO:0009378)
0.9 3.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.8 2.3 GO:1990763 arrestin family protein binding(GO:1990763)
0.7 6.8 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.5 5.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.5 3.8 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.5 3.8 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.5 2.5 GO:0042731 PH domain binding(GO:0042731)
0.5 5.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.4 5.6 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.4 4.7 GO:0019864 IgG binding(GO:0019864)
0.4 5.0 GO:0070097 alpha-catenin binding(GO:0045294) delta-catenin binding(GO:0070097)
0.4 1.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.4 1.9 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.4 4.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.3 1.0 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.3 5.3 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.3 3.0 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.3 4.2 GO:0035497 cAMP response element binding(GO:0035497)
0.3 9.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.3 11.7 GO:0008009 chemokine activity(GO:0008009) CCR chemokine receptor binding(GO:0048020)
0.3 2.0 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.3 7.0 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 4.5 GO:0019789 SUMO transferase activity(GO:0019789)
0.2 8.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 5.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 2.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.2 4.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 0.5 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 0.9 GO:0051434 BH3 domain binding(GO:0051434)
0.1 2.4 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.6 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 0.6 GO:0033149 FFAT motif binding(GO:0033149)
0.1 2.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 2.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 3.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 0.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 5.2 GO:0005080 protein kinase C binding(GO:0005080)
0.1 7.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 6.2 GO:0003777 microtubule motor activity(GO:0003777)
0.1 2.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.7 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.5 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 5.0 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.1 7.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 1.8 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 3.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 9.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 2.3 GO:0042605 peptide antigen binding(GO:0042605)
0.1 1.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 2.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.8 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 6.8 GO:0042393 histone binding(GO:0042393)
0.0 3.0 GO:0002039 p53 binding(GO:0002039)
0.0 1.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 1.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 2.3 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 1.0 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 1.9 GO:0005518 collagen binding(GO:0005518)
0.0 0.8 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 4.8 GO:0003924 GTPase activity(GO:0003924)
0.0 1.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.7 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 10.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 8.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 2.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 1.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 0.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 3.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 2.3 PID ARF6 PATHWAY Arf6 signaling events
0.1 6.0 PID E2F PATHWAY E2F transcription factor network
0.0 1.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 3.0 PID TNF PATHWAY TNF receptor signaling pathway
0.0 2.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 12.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 2.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.0 PID ATM PATHWAY ATM pathway
0.0 2.2 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 7.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.5 3.8 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.5 13.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.5 14.4 REACTOME KINESINS Genes involved in Kinesins
0.4 4.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 7.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.3 8.3 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.3 5.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.3 3.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.3 3.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.3 4.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.2 4.8 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.2 11.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 13.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 1.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 5.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 5.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 4.8 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 7.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 5.0 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.3 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1 1.0 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 0.4 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 3.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 5.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.9 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 2.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.1 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 2.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives